Caenorhabditis elegans

39 known processes

lin-45 (CELE_Y73B6A.5)

Protein LIN-45

lin-45 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development GO:0009790 3052 0.872
positive regulation of small gtpase mediated signal transduction GO:0051057 7 0.837
Worm Fly
embryo development ending in birth or egg hatching GO:0009792 2992 0.836
vulval development GO:0040025 333 0.776
regulation of locomotion GO:0040012 161 0.681
Mouse
localization of cell GO:0051674 313 0.624
Mouse Worm Fly
cell motility GO:0048870 313 0.604
Mouse Worm Fly
post embryonic organ development GO:0048569 336 0.588
cell migration GO:0016477 306 0.588
Mouse Worm Fly
positive regulation of locomotion GO:0040017 42 0.583
organic substance catabolic process GO:1901575 294 0.579
Human
negative regulation of multicellular organismal process GO:0051241 236 0.567
single organism reproductive process GO:0044702 1196 0.508
Fly
cellular localization GO:0051641 360 0.506
Mouse
organelle organization GO:0006996 783 0.490
Mouse
signaling GO:0023052 401 0.478
reproductive structure development GO:0048608 850 0.469
aromatic compound biosynthetic process GO:0019438 192 0.463
Fly
gonad development GO:0008406 840 0.445
catabolic process GO:0009056 318 0.443
Human Fly
regulation of cell motility GO:2000145 57 0.434
Mouse
reproductive system development GO:0061458 850 0.427
establishment of localization GO:0051234 1171 0.405
Mouse
sex differentiation GO:0007548 909 0.405
Worm
signal transduction GO:0007165 317 0.390
organ development GO:0048513 1102 0.378
cell cycle GO:0007049 526 0.376
Worm Fly
post embryonic development GO:0009791 2152 0.375
cellular component movement GO:0006928 388 0.374
Mouse Worm Fly
regulation of signal transduction GO:0009966 135 0.372
Human Mouse Rat Worm Fly
cell cycle process GO:0022402 482 0.368
developmental process involved in reproduction GO:0003006 1165 0.364
Worm Fly
regulation of cell migration GO:0030334 55 0.363
Mouse
embryonic pattern specification GO:0009880 21 0.354
Fly
positive regulation of nucleic acid templated transcription GO:1903508 102 0.346
cellular nitrogen compound biosynthetic process GO:0044271 192 0.345
Fly
regulation of macromolecule metabolic process GO:0060255 421 0.343
Human Rat Fly
positive regulation of ras protein signal transduction GO:0046579 7 0.337
Worm Fly
programmed cell death GO:0012501 500 0.337
Human Mouse Fly
nucleobase containing compound metabolic process GO:0006139 406 0.330
Fly
positive regulation of cell migration GO:0030335 3 0.327
protein metabolic process GO:0019538 422 0.322
Human Mouse Rat Worm Fly
cellular macromolecule biosynthetic process GO:0034645 247 0.321
Fly
single organism signaling GO:0044700 401 0.313
organonitrogen compound metabolic process GO:1901564 151 0.311
single organism organelle organization GO:1902589 501 0.309
Mouse
macromolecule catabolic process GO:0009057 202 0.309
Human
regulation of intracellular signal transduction GO:1902531 77 0.303
Human Mouse Rat Worm Fly
regulation of developmental process GO:0050793 684 0.298
Mouse Fly
phosphorus metabolic process GO:0006793 232 0.295
Human Mouse Rat Worm Fly
regulation of cellular component organization GO:0051128 248 0.289
Human Mouse
phosphate containing compound metabolic process GO:0006796 232 0.288
Human Mouse Rat Worm Fly
single organism transport GO:0044765 447 0.285
Mouse
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.280
mitotic cell cycle process GO:1903047 194 0.271
positive regulation of signal transduction GO:0009967 40 0.262
Human Mouse Rat Worm Fly
regulation of vulval development GO:0040028 248 0.251
hermaphrodite genitalia development GO:0040035 734 0.251
positive regulation of gene expression GO:0010628 112 0.249
Human
regulation of localization GO:0032879 194 0.249
Mouse
regulation of cellular component movement GO:0051270 62 0.244
Mouse
negative regulation of vulval development GO:0040027 206 0.241
transport GO:0006810 1093 0.235
Mouse
axis specification GO:0009798 23 0.234
Fly
body morphogenesis GO:0010171 620 0.233
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.233
negative regulation of biological process GO:0048519 567 0.232
Human Mouse Fly
death GO:0016265 547 0.228
Human Mouse Fly
regulation of rna biosynthetic process GO:2001141 165 0.228
Fly
genitalia development GO:0048806 741 0.226
protein complex subunit organization GO:0071822 280 0.223
Human Mouse
regulation of anatomical structure size GO:0090066 46 0.222
development of primary sexual characteristics GO:0045137 840 0.220
multicellular organismal reproductive process GO:0048609 815 0.220
Fly
guanosine containing compound metabolic process GO:1901068 49 0.220
regulation of biological quality GO:0065008 741 0.219
Mouse
purine ribonucleotide catabolic process GO:0009154 75 0.211
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.210
nucleotide metabolic process GO:0009117 108 0.204
regulation of multicellular organismal development GO:2000026 317 0.203
Fly
regulation of multicellular organismal process GO:0051239 726 0.201
Fly
single organism localization GO:1902578 518 0.194
Mouse
nucleobase containing compound biosynthetic process GO:0034654 184 0.191
Fly
regulation of nematode larval development GO:0061062 260 0.191
epithelium development GO:0060429 68 0.190
Fly
organophosphate metabolic process GO:0019637 125 0.189
regulation of response to stimulus GO:0048583 243 0.185
Human Mouse Rat Worm Fly
regulation of metabolic process GO:0019222 478 0.185
Human Mouse Rat Fly
determination of adult lifespan GO:0008340 812 0.183
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.178
cellular catabolic process GO:0044248 199 0.174
Human Fly
biosynthetic process GO:0009058 323 0.173
Fly
regulation of nucleic acid templated transcription GO:1903506 165 0.170
Fly
regulation of phosphorus metabolic process GO:0051174 81 0.170
Human Mouse Rat Fly
establishment of localization in cell GO:0051649 318 0.168
Mouse
regulation of mapk cascade GO:0043408 23 0.168
Human Mouse Rat Fly
regulation of cell communication GO:0010646 176 0.167
Human Mouse Rat Worm Fly
positive regulation of transcription dna templated GO:0045893 102 0.167
purine ribonucleotide metabolic process GO:0009150 95 0.165
single organism cellular localization GO:1902580 72 0.163
positive regulation of signaling GO:0023056 66 0.162
Human Mouse Rat Worm Fly
oocyte construction GO:0007308 2 0.161
establishment of organelle localization GO:0051656 123 0.161
Mouse
anterior posterior pattern specification GO:0009952 27 0.156
Fly
multi organism reproductive process GO:0044703 867 0.151
Fly
nucleoside triphosphate metabolic process GO:0009141 87 0.150
macromolecule localization GO:0033036 771 0.148
positive regulation of cellular biosynthetic process GO:0031328 109 0.148
positive regulation of metabolic process GO:0009893 187 0.148
Human Mouse Rat Fly
macromolecule biosynthetic process GO:0009059 250 0.148
Fly
ras protein signal transduction GO:0007265 31 0.148
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.148
Fly
regulation of rna metabolic process GO:0051252 173 0.143
Fly
purine nucleotide metabolic process GO:0006163 95 0.142
small gtpase mediated signal transduction GO:0007264 32 0.141
negative regulation of nematode larval development GO:0061064 208 0.139
cell projection morphogenesis GO:0048858 148 0.138
gtp catabolic process GO:0006184 46 0.136
regulation of signaling GO:0023051 172 0.136
Human Mouse Rat Worm Fly
small molecule metabolic process GO:0044281 186 0.131
nucleoside phosphate metabolic process GO:0006753 108 0.130
organelle fission GO:0048285 363 0.129
positive regulation of rna biosynthetic process GO:1902680 102 0.127
positive regulation of response to stimulus GO:0048584 55 0.127
Human Mouse Rat Worm Fly
heterocycle catabolic process GO:0046700 119 0.127
nucleic acid templated transcription GO:0097659 169 0.124
Fly
cell projection organization GO:0030030 231 0.122
vesicle mediated transport GO:0016192 852 0.122
Mouse
apoptotic process GO:0006915 478 0.122
Human Mouse Fly
nucleoside triphosphate catabolic process GO:0009143 72 0.120
ribonucleoside metabolic process GO:0009119 98 0.118
regulation of post embryonic development GO:0048580 260 0.118
oocyte axis specification GO:0007309 2 0.117
cell death GO:0008219 547 0.116
Human Mouse Fly
nucleobase containing compound catabolic process GO:0034655 114 0.116
negative regulation of cellular process GO:0048523 239 0.115
Human Mouse Fly
gamete generation GO:0007276 461 0.114
Fly
cellular protein metabolic process GO:0044267 279 0.112
Human Mouse Rat Worm Fly
neurogenesis GO:0022008 236 0.111
Fly
response to wounding GO:0009611 4 0.109
behavior GO:0007610 527 0.107
Mouse
actin filament based process GO:0030029 191 0.107
Mouse
positive regulation of gtpase activity GO:0043547 28 0.106
sexual reproduction GO:0019953 546 0.106
Fly
regulation of gtp catabolic process GO:0033124 32 0.105
negative regulation of cell cycle GO:0045786 53 0.105
phosphorylation GO:0016310 116 0.104
Human Mouse Rat Worm Fly
nucleoside metabolic process GO:0009116 99 0.104
nucleobase containing small molecule metabolic process GO:0055086 115 0.104
gene expression GO:0010467 412 0.104
Human Fly
purine nucleoside metabolic process GO:0042278 92 0.102
positive regulation of cell communication GO:0010647 69 0.101
Human Mouse Rat Worm Fly
microtubule based process GO:0007017 182 0.101
heterocycle biosynthetic process GO:0018130 187 0.101
Fly
system process GO:0003008 136 0.098
Mouse
single organism biosynthetic process GO:0044711 91 0.097
nucleoside phosphate catabolic process GO:1901292 77 0.096
multicellular organism reproduction GO:0032504 819 0.095
Fly
regulation of primary metabolic process GO:0080090 292 0.095
Human Rat Fly
positive regulation of phosphorus metabolic process GO:0010562 56 0.093
Human Mouse Rat Fly
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.093
Fly
single organism catabolic process GO:0044712 129 0.091
Fly
multicellular organismal aging GO:0010259 812 0.090
regulation of biosynthetic process GO:0009889 189 0.090
Fly
carboxylic acid metabolic process GO:0019752 34 0.090
regulation of cell cycle GO:0051726 194 0.089
Fly
locomotion GO:0040011 1634 0.089
Mouse Worm Fly
regulation of purine nucleotide metabolic process GO:1900542 37 0.089
regionalization GO:0003002 31 0.089
Fly
positive regulation of mapk cascade GO:0043410 14 0.087
Human Mouse Rat Fly
nucleic acid metabolic process GO:0090304 299 0.087
Fly
anterior posterior axis specification GO:0009948 17 0.087
Fly
regulation of catabolic process GO:0009894 57 0.086
Human Fly
oviposition GO:0018991 364 0.085
cellular component assembly GO:0022607 293 0.085
Human Mouse
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.085
cellular lipid metabolic process GO:0044255 40 0.083
microtubule based movement GO:0007018 33 0.083
negative regulation of post embryonic development GO:0048581 208 0.083
positive regulation of biosynthetic process GO:0009891 109 0.083
carbohydrate derivative metabolic process GO:1901135 141 0.080
organic cyclic compound biosynthetic process GO:1901362 195 0.080
Fly
positive regulation of purine nucleotide metabolic process GO:1900544 28 0.080
cytoskeleton organization GO:0007010 339 0.080
Mouse
regulation of growth GO:0040008 409 0.079
Fly
multicellular organismal reproductive behavior GO:0033057 384 0.078
ribose phosphate metabolic process GO:0019693 99 0.078
organic cyclic compound catabolic process GO:1901361 119 0.077
ribonucleoside catabolic process GO:0042454 77 0.077
nucleoside catabolic process GO:0009164 78 0.076
reproductive behavior GO:0019098 387 0.075
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.075
positive regulation of phosphorylation GO:0042327 27 0.075
Human Mouse Rat Fly
positive regulation of multicellular organismal process GO:0051240 417 0.074
Fly
glycosyl compound catabolic process GO:1901658 79 0.074
positive regulation of nucleoside metabolic process GO:0045979 28 0.073
purine containing compound metabolic process GO:0072521 95 0.072
generation of neurons GO:0048699 235 0.072
Fly
purine nucleoside triphosphate metabolic process GO:0009144 87 0.072
intracellular signal transduction GO:0035556 96 0.069
tissue morphogenesis GO:0048729 65 0.069
Fly
cellular protein modification process GO:0006464 207 0.068
Human Mouse Rat Worm Fly
positive regulation of developmental process GO:0051094 408 0.068
Mouse Fly
ribonucleotide catabolic process GO:0009261 75 0.066
positive regulation of cellular process GO:0048522 332 0.066
Human Mouse Rat Worm Fly
protein catabolic process GO:0030163 162 0.066
Human
purine nucleoside triphosphate catabolic process GO:0009146 72 0.066
tissue development GO:0009888 112 0.066
Fly
aging GO:0007568 812 0.066
mapk cascade GO:0000165 31 0.065
Human Mouse Rat Fly
germ cell development GO:0007281 351 0.063
Fly
oxoacid metabolic process GO:0043436 47 0.061
regulation of transcription dna templated GO:0006355 164 0.061
Fly
regulation of macromolecule biosynthetic process GO:0010556 189 0.061
Fly
organic substance biosynthetic process GO:1901576 323 0.061
Fly
cell proliferation GO:0008283 116 0.060
Human Mouse Fly
maintenance of location GO:0051235 580 0.059
cellular nitrogen compound catabolic process GO:0044270 119 0.059
lipid storage GO:0019915 565 0.058
regulation of multicellular organism growth GO:0040014 373 0.058
Fly
regulation of organelle organization GO:0033043 164 0.057
Mouse
neuron development GO:0048666 199 0.057
ribonucleotide metabolic process GO:0009259 99 0.056
female gamete generation GO:0007292 254 0.055
Fly
growth GO:0040007 562 0.055
Fly
neuron projection development GO:0031175 187 0.055
regulation of purine nucleotide catabolic process GO:0033121 35 0.055
head development GO:0060322 1 0.055
lipid localization GO:0010876 573 0.054
positive regulation of gtp catabolic process GO:0033126 28 0.054
protein complex assembly GO:0006461 186 0.054
Human Mouse
regulation of molecular function GO:0065009 89 0.054
Rat
segmentation GO:0035282 7 0.053
Fly
nucleotide catabolic process GO:0009166 77 0.053
cell development GO:0048468 696 0.052
Mouse Fly
purine nucleoside catabolic process GO:0006152 75 0.052
macromolecular complex assembly GO:0065003 193 0.052
Human Mouse
cellular response to nutrient levels GO:0031669 13 0.052
Fly
multi organism behavior GO:0051705 389 0.052
regulation of nucleotide catabolic process GO:0030811 35 0.052
protein modification process GO:0036211 207 0.051
Human Mouse Rat Worm Fly
multicellular organism growth GO:0035264 385 0.051
Fly
ribonucleoside triphosphate catabolic process GO:0009203 72 0.051
purine ribonucleoside catabolic process GO:0046130 75 0.050
organonitrogen compound catabolic process GO:1901565 90 0.049
regulation of small gtpase mediated signal transduction GO:0051056 41 0.049
Worm Fly
positive regulation of macromolecule metabolic process GO:0010604 149 0.049
Human Rat
tube development GO:0035295 126 0.049
Fly
aromatic compound catabolic process GO:0019439 116 0.048
regulation of cellular metabolic process GO:0031323 305 0.048
Human Mouse Rat Fly
meiotic nuclear division GO:0007126 300 0.048
developmental growth GO:0048589 412 0.047
Fly
cellular component morphogenesis GO:0032989 318 0.047
Mouse
protein localization GO:0008104 205 0.047
pattern specification process GO:0007389 59 0.046
Fly
digestive tract development GO:0048565 122 0.046
Fly
nuclear migration GO:0007097 54 0.046
purine nucleotide catabolic process GO:0006195 75 0.046
guanosine containing compound catabolic process GO:1901069 48 0.045
oocyte development GO:0048599 44 0.045
actin cytoskeleton organization GO:0030036 184 0.045
Mouse
regulation of meiotic cell cycle GO:0051445 136 0.045
positive regulation of purine nucleotide catabolic process GO:0033123 28 0.044
multi organism reproductive behavior GO:0044705 387 0.044
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.044
Fly
organelle assembly GO:0070925 214 0.043
cellular response to stress GO:0033554 162 0.043
Fly
cell surface receptor signaling pathway GO:0007166 149 0.042
Mouse Fly
positive regulation of catabolic process GO:0009896 38 0.042
single organism intracellular transport GO:1902582 70 0.042
g protein coupled receptor signaling pathway GO:0007186 46 0.042
homeostatic process GO:0042592 51 0.041
positive regulation of hydrolase activity GO:0051345 38 0.041
oogenesis GO:0048477 229 0.041
Fly
multi multicellular organism process GO:0044706 390 0.041
oocyte differentiation GO:0009994 45 0.041
regulation of phosphate metabolic process GO:0019220 81 0.041
Human Mouse Rat Fly
peptidyl serine phosphorylation GO:0018105 20 0.040
Human
regulation of developmental growth GO:0048638 389 0.040
Fly
negative regulation of macromolecule metabolic process GO:0010605 229 0.040
positive regulation of developmental growth GO:0048639 354 0.040
monocarboxylic acid metabolic process GO:0032787 22 0.040
cellular response to abiotic stimulus GO:0071214 4 0.040
regulation of ras protein signal transduction GO:0046578 41 0.040
Worm Fly
cellular biosynthetic process GO:0044249 315 0.039
Fly
endocytosis GO:0006897 819 0.039
negative regulation of cellular metabolic process GO:0031324 95 0.039
Fly
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.039
Fly
mitotic nuclear division GO:0007067 89 0.038
cellular macromolecule localization GO:0070727 75 0.038
positive regulation of growth GO:0045927 369 0.038
cellular amine metabolic process GO:0044106 15 0.037
tube morphogenesis GO:0035239 79 0.037
Fly
cellular component biogenesis GO:0044085 297 0.036
Human Mouse
signal transduction by phosphorylation GO:0023014 31 0.036
Human Mouse Rat Fly
muscle system process GO:0003012 43 0.036
autophagy GO:0006914 29 0.035
Fly
response to nutrient levels GO:0031667 35 0.035
Fly
cellular protein localization GO:0034613 75 0.033
membrane organization GO:0061024 135 0.033
glycosyl compound metabolic process GO:1901657 100 0.033
macroautophagy GO:0016236 11 0.033
Fly
negative regulation of metabolic process GO:0009892 240 0.033
Fly
blastoderm segmentation GO:0007350 7 0.033
Fly
intracellular transport GO:0046907 77 0.032
organelle localization GO:0051640 127 0.032
Mouse
lipid metabolic process GO:0006629 77 0.032
cellular ketone metabolic process GO:0042180 14 0.032
epidermis development GO:0008544 24 0.031
cell cycle switching mitotic to meiotic cell cycle GO:0051728 35 0.031
ion transmembrane transport GO:0034220 91 0.031
meiotic cell cycle GO:0051321 335 0.031
Worm
nervous system development GO:0007399 253 0.031
Fly
protein oligomerization GO:0051259 4 0.030
regulation of nucleotide metabolic process GO:0006140 37 0.030
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.030
rna biosynthetic process GO:0032774 169 0.029
Fly
muscle cell development GO:0055001 158 0.029
positive regulation of cellular catabolic process GO:0031331 35 0.029
cell adhesion GO:0007155 21 0.029
Mouse
establishment of protein localization to membrane GO:0090150 3 0.028
bmp signaling pathway GO:0030509 3 0.028
peptidyl serine modification GO:0018209 20 0.028
Human
response to starvation GO:0042594 26 0.028
Fly
positive regulation of epithelial cell proliferation GO:0050679 1 0.028
skin development GO:0043588 24 0.027
amine metabolic process GO:0009308 15 0.027
regulation of catalytic activity GO:0050790 78 0.027
Rat
establishment or maintenance of cell polarity GO:0007163 63 0.027
Fly
purine containing compound catabolic process GO:0072523 75 0.027
positive regulation of intracellular signal transduction GO:1902533 24 0.027
Human Mouse Rat Worm Fly
purine ribonucleoside metabolic process GO:0046128 92 0.027
muscle cell differentiation GO:0042692 171 0.027
organophosphate catabolic process GO:0046434 81 0.027
lipid biosynthetic process GO:0008610 28 0.027
negative regulation of signal transduction GO:0009968 60 0.027
Mouse Fly
positive regulation of kinase activity GO:0033674 19 0.027
Rat
regulation of response to stress GO:0080134 28 0.027
Fly
negative regulation of mitotic cell cycle GO:0045930 42 0.026
regulation of lipid metabolic process GO:0019216 4 0.026
protein phosphorylation GO:0006468 85 0.026
Human Mouse Rat Worm Fly
peptidyl amino acid modification GO:0018193 58 0.026
Human
neuron projection morphogenesis GO:0048812 114 0.026
positive regulation of multicellular organism growth GO:0040018 352 0.026
regulation of phosphorylation GO:0042325 45 0.026
Human Mouse Rat Fly
embryonic axis specification GO:0000578 9 0.025
Fly
organic substance transport GO:0071702 113 0.025
single organism nuclear import GO:1902593 6 0.025
tripartite regional subdivision GO:0007351 7 0.025
Fly
receptor mediated endocytosis GO:0006898 715 0.025
cellular component assembly involved in morphogenesis GO:0010927 183 0.024
regulation of endocytosis GO:0030100 25 0.024
chromosome segregation GO:0007059 180 0.024
carbohydrate derivative catabolic process GO:1901136 82 0.023
rho protein signal transduction GO:0007266 2 0.023
protein complex biogenesis GO:0070271 186 0.023
Human Mouse
rna localization GO:0006403 3 0.023
positive regulation of rna metabolic process GO:0051254 103 0.023
ribonucleoside triphosphate metabolic process GO:0009199 87 0.023
response to organic substance GO:0010033 131 0.023
Mouse
transcription from rna polymerase ii promoter GO:0006366 149 0.023
Fly
actomyosin structure organization GO:0031032 154 0.023
Mouse
molting cycle GO:0042303 281 0.023
muscle contraction GO:0006936 43 0.023
regulation of cellular biosynthetic process GO:0031326 189 0.023
Fly
striated muscle cell development GO:0055002 157 0.023
myosin filament assembly GO:0031034 138 0.022
regulation of cytoplasmic transport GO:1903649 3 0.022
regulation of hydrolase activity GO:0051336 45 0.022
neuromuscular junction development GO:0007528 2 0.022
endomembrane system organization GO:0010256 22 0.022
regulation of cell proliferation GO:0042127 105 0.022
Human Mouse Fly
positive regulation of neurogenesis GO:0050769 4 0.022
Fly
regulation of protein metabolic process GO:0051246 81 0.022
Human Rat
actin cytoskeleton reorganization GO:0031532 4 0.022
gtp metabolic process GO:0046039 46 0.022
negative regulation of neuron differentiation GO:0045665 4 0.022
regulation of cell death GO:0010941 65 0.022
Human Mouse Fly
regulation of cell cycle process GO:0010564 145 0.021
regulation of apoptotic process GO:0042981 36 0.021
Human Mouse Fly
neuron differentiation GO:0030182 217 0.021
Fly
organic acid metabolic process GO:0006082 47 0.021
cellular macromolecule catabolic process GO:0044265 73 0.021
Human
negative regulation of response to stimulus GO:0048585 73 0.021
Mouse Fly
regulation of bmp signaling pathway GO:0030510 3 0.021
cell cycle phase transition GO:0044770 19 0.021
cellular macromolecular complex assembly GO:0034622 184 0.021
regulation of response to wounding GO:1903034 1 0.020
inductive cell migration GO:0040039 145 0.020
negative regulation of developmental process GO:0051093 227 0.020
Mouse
membrane invagination GO:0010324 98 0.020
nucleus localization GO:0051647 55 0.020
regulation of cellular amine metabolic process GO:0033238 0 0.020
positive regulation of protein modification process GO:0031401 29 0.019
Human Rat
peptidyl tyrosine phosphorylation GO:0018108 2 0.019
organ morphogenesis GO:0009887 67 0.019
Fly
striated muscle cell differentiation GO:0051146 158 0.019
cellular response to starvation GO:0009267 13 0.019
Fly
regulation of gene expression GO:0010468 366 0.019
Human Fly
regulation of mitotic cell cycle GO:0007346 76 0.019
regulation of organ morphogenesis GO:2000027 4 0.019
regulation of synapse assembly GO:0051963 2 0.019
negative regulation of signaling GO:0023057 61 0.019
Mouse Fly
ion transport GO:0006811 113 0.019
regulation of nitrogen compound metabolic process GO:0051171 222 0.018
Fly
response to abiotic stimulus GO:0009628 152 0.018
Mouse
regulation of cellular ketone metabolic process GO:0010565 3 0.018
positive regulation of cell cycle GO:0045787 55 0.018
regulation of transferase activity GO:0051338 31 0.018
Rat
meiotic cell cycle process GO:1903046 170 0.018
regulation of kinase activity GO:0043549 29 0.017
Rat
cell cycle g1 s phase transition GO:0044843 2 0.017
negative regulation of neurogenesis GO:0050768 4 0.017
glycosaminoglycan biosynthetic process GO:0006024 5 0.017
regulation of apoptotic signaling pathway GO:2001233 1 0.017
Mouse Fly
regulation of ras gtpase activity GO:0032318 21 0.017
myosin filament organization GO:0031033 138 0.017
phagocytosis GO:0006909 115 0.017
neurological system process GO:0050877 53 0.017
Mouse
transmembrane transport GO:0055085 110 0.017
positive regulation of protein serine threonine kinase activity GO:0071902 12 0.016
Rat
response to external stimulus GO:0009605 289 0.016
Fly
protein localization to nucleus GO:0034504 11 0.016
regulation of epithelial cell proliferation GO:0050678 1 0.016
axon development GO:0061564 163 0.016
regulation of g protein coupled receptor protein signaling pathway GO:0008277 4 0.016
positive regulation of cellular metabolic process GO:0031325 178 0.016
Human Mouse Rat Fly
regulation of cellular amino acid metabolic process GO:0006521 0 0.016
cell maturation GO:0048469 26 0.015
regulation of gtpase activity GO:0043087 30 0.015
regulation of cell size GO:0008361 30 0.015
regulation of cell cell adhesion GO:0022407 1 0.015
positive regulation of meiotic cell cycle GO:0051446 47 0.015
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.015
protein localization to organelle GO:0033365 37 0.015
defense response GO:0006952 296 0.015
regulation of cellular response to stress GO:0080135 19 0.015
Fly
striated muscle myosin thick filament assembly GO:0071688 138 0.015
organonitrogen compound biosynthetic process GO:1901566 44 0.015
rna metabolic process GO:0016070 228 0.015
Fly
regulation of cellular component biogenesis GO:0044087 26 0.015
Human Mouse
positive regulation of map kinase activity GO:0043406 9 0.015
Rat
myofibril assembly GO:0030239 154 0.015
regulation of transport GO:0051049 91 0.015
Mouse
cell division GO:0051301 262 0.015
dephosphorylation GO:0016311 17 0.015
g1 s transition of mitotic cell cycle GO:0000082 2 0.014
regulation of lipid biosynthetic process GO:0046890 1 0.014
muscle tissue development GO:0060537 1 0.014
regulation of cellular component size GO:0032535 40 0.014
response to extracellular stimulus GO:0009991 38 0.014
Fly
peptidyl tyrosine modification GO:0018212 3 0.014
protein import GO:0017038 9 0.014
regulation of cellular catabolic process GO:0031329 51 0.014
Human Fly
cell growth GO:0016049 44 0.014
protein transport GO:0015031 45 0.014
cytoskeleton dependent intracellular transport GO:0030705 19 0.014
negative regulation of cell communication GO:0010648 61 0.014
Mouse Fly
regulation of neuron differentiation GO:0045664 40 0.014
Fly
positive regulation of jnk cascade GO:0046330 3 0.014
regulation of protein kinase activity GO:0045859 28 0.014
Rat
pigmentation GO:0043473 2 0.013
response to temperature stimulus GO:0009266 66 0.013
cellular response to metal ion GO:0071248 3 0.013
Human
regulation of protein serine threonine kinase activity GO:0071900 18 0.013
Rat
regulation of nucleoside metabolic process GO:0009118 37 0.013
organophosphate ester transport GO:0015748 5 0.013
skeletal muscle organ development GO:0060538 3 0.013
pigment biosynthetic process GO:0046148 2 0.013
cellular response to external stimulus GO:0071496 16 0.013
Fly
epithelial cell proliferation GO:0050673 1 0.013
response to chemical GO:0042221 356 0.013
Human Mouse
axonogenesis GO:0007409 102 0.013
establishment of nucleus localization GO:0040023 55 0.012
regulation of muscle contraction GO:0006937 20 0.012
digestive system development GO:0055123 122 0.012
Fly
monosaccharide metabolic process GO:0005996 2 0.012
apoptotic cell clearance GO:0043277 111 0.012
inorganic ion transmembrane transport GO:0098660 54 0.012
endosomal transport GO:0016197 26 0.012
negative regulation of cell morphogenesis involved in differentiation GO:0010771 2 0.012
male sex differentiation GO:0046661 86 0.012
Worm
establishment of protein localization to organelle GO:0072594 9 0.012
cellular protein complex assembly GO:0043623 178 0.012
positive regulation of ras gtpase activity GO:0032320 19 0.012
positive regulation of phosphate metabolic process GO:0045937 56 0.012
Human Mouse Rat Fly
regulation of cell differentiation GO:0045595 81 0.011
Mouse Fly
carbohydrate metabolic process GO:0005975 34 0.011
positive regulation of catalytic activity GO:0043085 59 0.011
Rat
actin filament organization GO:0007015 21 0.011
Mouse
sensory organ morphogenesis GO:0090596 2 0.011
establishment of vesicle localization GO:0051650 23 0.011
Mouse
defense response to other organism GO:0098542 100 0.011
positive regulation of stress activated mapk cascade GO:0032874 3 0.011

lin-45 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.026
Human
nervous system disease DOID:863 0 0.020