Caenorhabditis elegans

33 known processes

sec-16 (CELE_ZK512.5)

Protein SEC-16

sec-16 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of macromolecule metabolic process GO:0060255 421 0.553
embryo development GO:0009790 3052 0.483
regulation of primary metabolic process GO:0080090 292 0.444
nucleic acid metabolic process GO:0090304 299 0.430
cell cycle GO:0007049 526 0.395
nucleobase containing compound metabolic process GO:0006139 406 0.391
regulation of cellular metabolic process GO:0031323 305 0.361
gene expression GO:0010467 412 0.332
developmental process involved in reproduction GO:0003006 1165 0.268
negative regulation of biological process GO:0048519 567 0.237
regulation of metabolic process GO:0019222 478 0.221
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.203
embryo development ending in birth or egg hatching GO:0009792 2992 0.192
regulation of gene expression GO:0010468 366 0.190
determination of adult lifespan GO:0008340 812 0.187
regulation of cellular component organization GO:0051128 248 0.186
meiotic nuclear division GO:0007126 300 0.184
regulation of nitrogen compound metabolic process GO:0051171 222 0.160
aging GO:0007568 812 0.159
post embryonic development GO:0009791 2152 0.155
biosynthetic process GO:0009058 323 0.154
cell development GO:0048468 696 0.149
locomotion GO:0040011 1634 0.147
aromatic compound biosynthetic process GO:0019438 192 0.145
meiotic chromosome segregation GO:0045132 139 0.145
positive regulation of cellular process GO:0048522 332 0.132
body morphogenesis GO:0010171 620 0.131
cell division GO:0051301 262 0.130
rna metabolic process GO:0016070 228 0.128
multicellular organismal aging GO:0010259 812 0.126
regulation of rna biosynthetic process GO:2001141 165 0.120
cell cycle process GO:0022402 482 0.119
macromolecule biosynthetic process GO:0009059 250 0.116
organelle fission GO:0048285 363 0.108
transport GO:0006810 1093 0.108
organ development GO:0048513 1102 0.101
macromolecule modification GO:0043412 218 0.099
positive regulation of metabolic process GO:0009893 187 0.099
organic substance biosynthetic process GO:1901576 323 0.099
germ cell development GO:0007281 351 0.096
negative regulation of metabolic process GO:0009892 240 0.095
negative regulation of cellular process GO:0048523 239 0.094
oogenesis GO:0048477 229 0.093
signal transduction GO:0007165 317 0.093
organic cyclic compound biosynthetic process GO:1901362 195 0.090
gene silencing GO:0016458 143 0.089
growth GO:0040007 562 0.087
chromosome segregation GO:0007059 180 0.086
regulation of rna metabolic process GO:0051252 173 0.086
heterocycle biosynthetic process GO:0018130 187 0.085
regulation of organelle organization GO:0033043 164 0.084
cellular component biogenesis GO:0044085 297 0.084
regulation of multicellular organismal process GO:0051239 726 0.083
single organism transport GO:0044765 447 0.082
single organism reproductive process GO:0044702 1196 0.081
regulation of biological quality GO:0065008 741 0.081
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.081
macromolecule localization GO:0033036 771 0.080
regulation of cell division GO:0051302 142 0.079
mitotic cell cycle process GO:1903047 194 0.078
nucleic acid templated transcription GO:0097659 169 0.077
regulation of growth GO:0040008 409 0.075
meiotic cell cycle process GO:1903046 170 0.075
regulation of biosynthetic process GO:0009889 189 0.075
cellular nitrogen compound biosynthetic process GO:0044271 192 0.074
single organism signaling GO:0044700 401 0.074
meiotic cell cycle GO:0051321 335 0.074
developmental growth GO:0048589 412 0.074
negative regulation of macromolecule metabolic process GO:0010605 229 0.073
gamete generation GO:0007276 461 0.073
death GO:0016265 547 0.071
single organism localization GO:1902578 518 0.070
regulation of signaling GO:0023051 172 0.070
signaling GO:0023052 401 0.066
positive regulation of cellular metabolic process GO:0031325 178 0.065
reproductive structure development GO:0048608 850 0.064
sensory organ morphogenesis GO:0090596 2 0.063
rna biosynthetic process GO:0032774 169 0.062
hermaphrodite genitalia development GO:0040035 734 0.062
single organism organelle organization GO:1902589 501 0.062
regulation of transcription dna templated GO:0006355 164 0.062
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.061
vulval development GO:0040025 333 0.060
maintenance of location GO:0051235 580 0.060
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.059
lipid storage GO:0019915 565 0.059
innate immune response GO:0045087 190 0.058
organic cyclic compound catabolic process GO:1901361 119 0.057
macromolecule catabolic process GO:0009057 202 0.057
sexual reproduction GO:0019953 546 0.057
positive regulation of developmental growth GO:0048639 354 0.056
programmed cell death GO:0012501 500 0.056
cellular response to stress GO:0033554 162 0.055
regulation of gene expression epigenetic GO:0040029 163 0.055
posttranscriptional regulation of gene expression GO:0010608 166 0.054
lipid localization GO:0010876 573 0.054
mitotic nuclear division GO:0007067 89 0.054
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.054
negative regulation of gene expression GO:0010629 217 0.054
regulation of developmental growth GO:0048638 389 0.051
cell death GO:0008219 547 0.050
gene silencing by rna GO:0031047 143 0.050
cell fate commitment GO:0045165 139 0.050
reproductive system development GO:0061458 850 0.050
organelle organization GO:0006996 783 0.049
regulation of multicellular organism growth GO:0040014 373 0.049
cellular response to chemical stimulus GO:0070887 129 0.046
vesicle mediated transport GO:0016192 852 0.046
posttranscriptional gene silencing GO:0016441 143 0.046
multicellular organism reproduction GO:0032504 819 0.046
regulation of meiotic cell cycle GO:0051445 136 0.046
heterocycle catabolic process GO:0046700 119 0.045
regulation of localization GO:0032879 194 0.045
catabolic process GO:0009056 318 0.044
muscle structure development GO:0061061 191 0.044
rna localization GO:0006403 3 0.044
positive regulation of neurogenesis GO:0050769 4 0.044
multicellular organismal reproductive process GO:0048609 815 0.044
cellular component morphogenesis GO:0032989 318 0.043
multi organism behavior GO:0051705 389 0.043
multicellular organism growth GO:0035264 385 0.043
sister chromatid segregation GO:0000819 46 0.042
positive regulation of growth GO:0045927 369 0.042
endocytosis GO:0006897 819 0.042
gonad development GO:0008406 840 0.041
positive regulation of cell morphogenesis involved in differentiation GO:0010770 4 0.041
positive regulation of multicellular organismal process GO:0051240 417 0.041
cellular component assembly GO:0022607 293 0.041
positive regulation of developmental process GO:0051094 408 0.041
positive regulation of gene expression GO:0010628 112 0.040
cellular biosynthetic process GO:0044249 315 0.040
protein complex subunit organization GO:0071822 280 0.040
regulation of multicellular organismal development GO:2000026 317 0.040
posttranscriptional gene silencing by rna GO:0035194 143 0.040
cellular catabolic process GO:0044248 199 0.040
female gamete generation GO:0007292 254 0.040
cellular macromolecule biosynthetic process GO:0034645 247 0.039
secretion GO:0046903 147 0.038
neurogenesis GO:0022008 236 0.038
membrane organization GO:0061024 135 0.037
regulation of cell cycle GO:0051726 194 0.037
organic substance catabolic process GO:1901575 294 0.037
regulation of response to stimulus GO:0048583 243 0.037
protein metabolic process GO:0019538 422 0.036
organophosphate ester transport GO:0015748 5 0.036
regulation of signal transduction GO:0009966 135 0.036
regulation of cell communication GO:0010646 176 0.035
regulation of cellular protein metabolic process GO:0032268 75 0.035
positive regulation of catalytic activity GO:0043085 59 0.035
oocyte construction GO:0007308 2 0.035
oocyte differentiation GO:0009994 45 0.034
cellular localization GO:0051641 360 0.034
organonitrogen compound metabolic process GO:1901564 151 0.033
development of primary sexual characteristics GO:0045137 840 0.033
regulation of developmental process GO:0050793 684 0.033
nucleobase containing compound catabolic process GO:0034655 114 0.032
nucleoside phosphate metabolic process GO:0006753 108 0.032
small molecule metabolic process GO:0044281 186 0.031
nucleobase containing compound biosynthetic process GO:0034654 184 0.031
cellular protein modification process GO:0006464 207 0.030
mitotic sister chromatid segregation GO:0000070 38 0.030
actin filament based process GO:0030029 191 0.030
regulation of macromolecule biosynthetic process GO:0010556 189 0.030
phosphorus metabolic process GO:0006793 232 0.029
regulation of nuclear division GO:0051783 115 0.029
transcription dna templated GO:0006351 168 0.029
rna interference GO:0016246 137 0.029
rrna metabolic process GO:0016072 3 0.029
genitalia development GO:0048806 741 0.029
cellular nitrogen compound catabolic process GO:0044270 119 0.028
sex differentiation GO:0007548 909 0.028
regulation of phosphate metabolic process GO:0019220 81 0.028
regulation of nematode larval development GO:0061062 260 0.027
multicellular organismal reproductive behavior GO:0033057 384 0.027
multi organism reproductive process GO:0044703 867 0.027
positive regulation of multicellular organism growth GO:0040018 352 0.027
phosphate containing compound metabolic process GO:0006796 232 0.027
asymmetric protein localization GO:0008105 35 0.026
aromatic compound catabolic process GO:0019439 116 0.026
apoptotic process GO:0006915 478 0.026
regulation of nucleic acid templated transcription GO:1903506 165 0.026
establishment of localization GO:0051234 1171 0.025
oocyte axis specification GO:0007309 2 0.025
regulation of cellular ketone metabolic process GO:0010565 3 0.025
regulation of cell differentiation GO:0045595 81 0.025
nervous system development GO:0007399 253 0.025
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.025
negative regulation of multicellular organismal process GO:0051241 236 0.025
carbohydrate derivative metabolic process GO:1901135 141 0.025
regulation of meiosis GO:0040020 94 0.025
positive regulation of macromolecule metabolic process GO:0010604 149 0.025
tissue development GO:0009888 112 0.024
cellular protein metabolic process GO:0044267 279 0.024
establishment of protein localization to membrane GO:0090150 3 0.024
negative regulation of developmental process GO:0051093 227 0.024
protein complex assembly GO:0006461 186 0.024
negative regulation of vulval development GO:0040027 206 0.024
ribosome biogenesis GO:0042254 4 0.024
response to chemical GO:0042221 356 0.023
neuron projection development GO:0031175 187 0.023
embryonic morphogenesis GO:0048598 152 0.023
negative regulation of gene expression epigenetic GO:0045814 2 0.023
cellular protein complex assembly GO:0043623 178 0.022
protein complex biogenesis GO:0070271 186 0.022
cell type specific apoptotic process GO:0097285 4 0.022
response to wounding GO:0009611 4 0.022
phagocytosis GO:0006909 115 0.022
neuron differentiation GO:0030182 217 0.022
macromolecular complex assembly GO:0065003 193 0.022
oocyte development GO:0048599 44 0.022
cellular macromolecule catabolic process GO:0044265 73 0.021
regulation of gastrulation GO:0010470 4 0.020
regulation of post embryonic development GO:0048580 260 0.020
cell projection organization GO:0030030 231 0.020
neuron projection morphogenesis GO:0048812 114 0.020
purine nucleoside metabolic process GO:0042278 92 0.020
oxoacid metabolic process GO:0043436 47 0.020
regulation of transport GO:0051049 91 0.019
neuron development GO:0048666 199 0.019
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.019
regulation of cell cycle process GO:0010564 145 0.019
negative regulation of cellular biosynthetic process GO:0031327 65 0.019
carboxylic acid metabolic process GO:0019752 34 0.019
receptor mediated endocytosis GO:0006898 715 0.019
defense response GO:0006952 296 0.019
actin cytoskeleton organization GO:0030036 184 0.019
cell projection morphogenesis GO:0048858 148 0.019
response to organic substance GO:0010033 131 0.019
positive regulation of cellular catabolic process GO:0031331 35 0.018
regulation of cellular biosynthetic process GO:0031326 189 0.018
generation of neurons GO:0048699 235 0.018
positive regulation of neuron differentiation GO:0045666 4 0.018
asymmetric stem cell division GO:0098722 8 0.018
digestive tract development GO:0048565 122 0.018
cell morphogenesis GO:0000902 163 0.018
secondary metabolite biosynthetic process GO:0044550 3 0.018
cellular ketone metabolic process GO:0042180 14 0.018
molting cycle GO:0042303 281 0.017
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.017
multi organism reproductive behavior GO:0044705 387 0.017
single organism biosynthetic process GO:0044711 91 0.017
regulation of locomotion GO:0040012 161 0.017
negative regulation of nematode larval development GO:0061064 208 0.017
regulation of vulval development GO:0040028 248 0.017
digestive system development GO:0055123 122 0.017
transcription from rna polymerase ii promoter GO:0006366 149 0.017
organic acid metabolic process GO:0006082 47 0.017
reproductive behavior GO:0019098 387 0.017
protein localization to plasma membrane GO:0072659 7 0.016
nucleoside metabolic process GO:0009116 99 0.016
golgi vesicle transport GO:0048193 3 0.016
cell proliferation GO:0008283 116 0.016
head development GO:0060322 1 0.016
positive regulation of rna biosynthetic process GO:1902680 102 0.016
protein modification process GO:0036211 207 0.016
pigment biosynthetic process GO:0046148 2 0.016
nucleobase containing small molecule metabolic process GO:0055086 115 0.016
organophosphate metabolic process GO:0019637 125 0.016
rna transport GO:0050658 3 0.015
oviposition GO:0018991 364 0.015
mrna metabolic process GO:0016071 31 0.015
ribose phosphate metabolic process GO:0019693 99 0.015
cuticle development GO:0042335 100 0.015
cell surface receptor signaling pathway GO:0007166 149 0.015
negative regulation of post embryonic development GO:0048581 208 0.015
protein localization GO:0008104 205 0.015
ribonucleotide metabolic process GO:0009259 99 0.015
pattern specification process GO:0007389 59 0.015
positive regulation of rna metabolic process GO:0051254 103 0.015
protein modification by small protein conjugation or removal GO:0070647 40 0.014
negative regulation of rna biosynthetic process GO:1902679 53 0.014
regulation of development heterochronic GO:0040034 18 0.014
cellular response to organic substance GO:0071310 119 0.014
regulation of axonogenesis GO:0050770 24 0.014
regulation of cellular amine metabolic process GO:0033238 0 0.014
neuronal stem cell division GO:0036445 9 0.014
cytoskeleton organization GO:0007010 339 0.014
regulation of vesicle mediated transport GO:0060627 27 0.014
synaptic vesicle localization GO:0097479 22 0.014
regulation of mitotic cell cycle GO:0007346 76 0.014
macromolecular complex subunit organization GO:0043933 320 0.014
nucleic acid transport GO:0050657 3 0.014
regulation of stem cell differentiation GO:2000736 1 0.014
cell morphogenesis involved in differentiation GO:0000904 112 0.014
ribonucleoprotein complex assembly GO:0022618 4 0.014
organonitrogen compound catabolic process GO:1901565 90 0.014
cell maturation GO:0048469 26 0.014
apical junction assembly GO:0043297 1 0.013
protein oligomerization GO:0051259 4 0.013
glycosyl compound metabolic process GO:1901657 100 0.013
secretion by cell GO:0032940 138 0.013
ribonucleotide catabolic process GO:0009261 75 0.013
tissue morphogenesis GO:0048729 65 0.013
regulation of protein metabolic process GO:0051246 81 0.013
regulation of cellular component movement GO:0051270 62 0.013
myosin filament assembly GO:0031034 138 0.013
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.013
phagocytosis engulfment GO:0006911 98 0.013
pigment metabolic process GO:0042440 2 0.013
nucleoside catabolic process GO:0009164 78 0.013
regulation of phosphorus metabolic process GO:0051174 81 0.013
synaptic growth at neuromuscular junction GO:0051124 1 0.013
regulation of cell proliferation GO:0042127 105 0.013
asymmetric cell division GO:0008356 36 0.013
cleavage involved in rrna processing GO:0000469 2 0.013
actin cytoskeleton reorganization GO:0031532 4 0.013
immune response GO:0006955 192 0.013
tube development GO:0035295 126 0.012
purine nucleotide catabolic process GO:0006195 75 0.012
regulation of multi organism process GO:0043900 69 0.012
positive regulation of catabolic process GO:0009896 38 0.012
cellular amino acid metabolic process GO:0006520 15 0.012
myofibril assembly GO:0030239 154 0.012
regeneration GO:0031099 4 0.012
cellular response to topologically incorrect protein GO:0035967 76 0.012
establishment of rna localization GO:0051236 3 0.012
positive regulation of nucleoside metabolic process GO:0045979 28 0.012
establishment of localization in cell GO:0051649 318 0.012
positive regulation of ras gtpase activity GO:0032320 19 0.012
stem cell division GO:0017145 18 0.012
regulation of cell development GO:0060284 49 0.012
positive regulation of cellular protein catabolic process GO:1903364 3 0.012
nucleotide metabolic process GO:0009117 108 0.011
somatic stem cell division GO:0048103 9 0.011
multi multicellular organism process GO:0044706 390 0.011
regulation of catalytic activity GO:0050790 78 0.011
positive regulation of nucleic acid templated transcription GO:1903508 102 0.011
negative regulation of neurogenesis GO:0050768 4 0.011
regulation of epithelial cell differentiation GO:0030856 4 0.011
regulation of embryonic development GO:0045995 16 0.011
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 1 0.011
positive regulation of neuron projection development GO:0010976 4 0.011
cytokinesis GO:0000910 80 0.011
regulation of molecular function GO:0065009 89 0.011
amine metabolic process GO:0009308 15 0.011
positive regulation of nucleotide catabolic process GO:0030813 28 0.011
positive regulation of transcription dna templated GO:0045893 102 0.011
behavior GO:0007610 527 0.011
myosin filament organization GO:0031033 138 0.011
purine ribonucleoside metabolic process GO:0046128 92 0.011
localization of cell GO:0051674 313 0.011
negative regulation of signal transduction GO:0009968 60 0.011
neuroblast division GO:0055057 9 0.011
protein deubiquitination GO:0016579 2 0.011
adult behavior GO:0030534 3 0.011
positive regulation of gtpase activity GO:0043547 28 0.010
regulation of cell motility GO:2000145 57 0.010
organ morphogenesis GO:0009887 67 0.010
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.010
regulation of cytoskeleton organization GO:0051493 41 0.010
mitotic g2 m transition checkpoint GO:0044818 1 0.010
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.010
muscle tissue development GO:0060537 1 0.010
cell part morphogenesis GO:0032990 152 0.010
purine containing compound catabolic process GO:0072523 75 0.010
regulation of cell morphogenesis involved in differentiation GO:0010769 29 0.010
regulation of neuron differentiation GO:0045664 40 0.010
response to unfolded protein GO:0006986 71 0.010
cell motility GO:0048870 313 0.010

sec-16 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.023
disease of metabolism DOID:0014667 0 0.016