Caenorhabditis elegans

67 known processes

aak-2 (CELE_T01C8.1)

Protein AAK-2

aak-2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development GO:0009790 3052 0.539
embryo development ending in birth or egg hatching GO:0009792 2992 0.536
negative regulation of biological process GO:0048519 567 0.512
endocytosis GO:0006897 819 0.484
Fly
dauer larval development GO:0040024 92 0.473
post embryonic development GO:0009791 2152 0.400
positive regulation of cellular process GO:0048522 332 0.389
establishment of localization GO:0051234 1171 0.379
Rat Fly
cell death GO:0008219 547 0.376
Mouse Worm
transport GO:0006810 1093 0.336
Rat Fly
positive regulation of macromolecule metabolic process GO:0010604 149 0.335
Human
locomotion GO:0040011 1634 0.299
Fly
response to organic substance GO:0010033 131 0.280
Mouse Rat
cellular localization GO:0051641 360 0.249
multicellular organismal aging GO:0010259 812 0.238
death GO:0016265 547 0.218
Mouse Worm
rna biosynthetic process GO:0032774 169 0.210
positive regulation of metabolic process GO:0009893 187 0.204
Human Mouse Rat
synaptic transmission GO:0007268 106 0.200
response to abiotic stimulus GO:0009628 152 0.194
Mouse Rat Fly
single organism catabolic process GO:0044712 129 0.188
Mouse Rat
developmental process involved in reproduction GO:0003006 1165 0.183
regulation of macromolecule metabolic process GO:0060255 421 0.180
Human Rat
programmed cell death GO:0012501 500 0.176
Mouse Worm
organelle organization GO:0006996 783 0.174
Mouse
single organism localization GO:1902578 518 0.168
Rat Fly
single organism reproductive process GO:0044702 1196 0.165
negative regulation of metabolic process GO:0009892 240 0.162
Mouse
establishment of localization in cell GO:0051649 318 0.162
oxoacid metabolic process GO:0043436 47 0.160
Mouse Rat
determination of adult lifespan GO:0008340 812 0.158
neurogenesis GO:0022008 236 0.156
Worm Fly
single organism signaling GO:0044700 401 0.153
Mouse
catabolic process GO:0009056 318 0.152
Mouse Rat
vesicle mediated transport GO:0016192 852 0.152
Rat Fly
regulation of metabolic process GO:0019222 478 0.150
Human Mouse Rat
phosphorus metabolic process GO:0006793 232 0.147
signaling GO:0023052 401 0.146
Mouse
nervous system development GO:0007399 253 0.144
Worm Fly
response to chemical GO:0042221 356 0.137
Mouse Rat Fly
autophagy GO:0006914 29 0.136
Mouse
organic substance catabolic process GO:1901575 294 0.135
Mouse Rat
single organism transport GO:0044765 447 0.135
Rat Fly
regulation of localization GO:0032879 194 0.130
Rat
regulation of intracellular signal transduction GO:1902531 77 0.129
Mouse
regulation of nitrogen compound metabolic process GO:0051171 222 0.127
cellular component biogenesis GO:0044085 297 0.127
Rat Worm
signal transduction GO:0007165 317 0.120
Mouse
macromolecule localization GO:0033036 771 0.119
Fly
regulation of nematode larval development GO:0061062 260 0.118
regulation of phosphate metabolic process GO:0019220 81 0.118
regulation of cell communication GO:0010646 176 0.111
Mouse
regulation of signaling GO:0023051 172 0.111
Mouse
gene expression GO:0010467 412 0.110
Human
cellular catabolic process GO:0044248 199 0.108
Mouse Rat
carboxylic acid catabolic process GO:0046395 3 0.108
cellular component assembly GO:0022607 293 0.107
Rat Worm
regulation of multicellular organismal process GO:0051239 726 0.106
female gamete generation GO:0007292 254 0.105
organic cyclic compound biosynthetic process GO:1901362 195 0.104
macromolecule biosynthetic process GO:0009059 250 0.100
regulation of protein metabolic process GO:0051246 81 0.099
phosphate containing compound metabolic process GO:0006796 232 0.099
organic substance biosynthetic process GO:1901576 323 0.098
Mouse
positive regulation of rna metabolic process GO:0051254 103 0.098
generation of neurons GO:0048699 235 0.098
Worm Fly
regulation of molecular function GO:0065009 89 0.098
cell development GO:0048468 696 0.095
Fly
nucleobase containing compound biosynthetic process GO:0034654 184 0.094
macromolecular complex assembly GO:0065003 193 0.093
Rat
cellular response to endogenous stimulus GO:0071495 32 0.091
Rat
positive regulation of phosphorus metabolic process GO:0010562 56 0.090
regulation of cellular metabolic process GO:0031323 305 0.090
Mouse Rat
regulation of phosphorus metabolic process GO:0051174 81 0.088
phosphorylation GO:0016310 116 0.088
regulation of nucleic acid templated transcription GO:1903506 165 0.087
regulation of biological quality GO:0065008 741 0.086
Mouse Rat Fly
intracellular signal transduction GO:0035556 96 0.086
Mouse
transcription dna templated GO:0006351 168 0.085
multi organism reproductive process GO:0044703 867 0.084
organic acid metabolic process GO:0006082 47 0.082
Mouse Rat
positive regulation of rna biosynthetic process GO:1902680 102 0.082
regulation of primary metabolic process GO:0080090 292 0.081
Mouse Rat
positive regulation of transcription dna templated GO:0045893 102 0.081
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.079
Fly
negative regulation of cellular biosynthetic process GO:0031327 65 0.079
regulation of transcription dna templated GO:0006355 164 0.079
transcription from rna polymerase ii promoter GO:0006366 149 0.078
positive regulation of multicellular organismal process GO:0051240 417 0.077
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.077
behavior GO:0007610 527 0.076
biosynthetic process GO:0009058 323 0.076
Mouse
organonitrogen compound metabolic process GO:1901564 151 0.075
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.075
positive regulation of catalytic activity GO:0043085 59 0.075
ion transport GO:0006811 113 0.073
maintenance of location GO:0051235 580 0.072
Fly
cellular biosynthetic process GO:0044249 315 0.072
cellular protein modification process GO:0006464 207 0.072
cytoskeleton organization GO:0007010 339 0.070
growth GO:0040007 562 0.069
Fly
oogenesis GO:0048477 229 0.069
multicellular organismal reproductive process GO:0048609 815 0.069
regulation of epithelial cell proliferation GO:0050678 1 0.069
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.069
positive regulation of signaling GO:0023056 66 0.068
cell migration GO:0016477 306 0.068
positive regulation of molecular function GO:0044093 61 0.067
anatomical structure formation involved in morphogenesis GO:0048646 250 0.067
positive regulation of developmental growth GO:0048639 354 0.066
cellular response to transforming growth factor beta stimulus GO:0071560 13 0.065
cation transport GO:0006812 78 0.065
heterocycle biosynthetic process GO:0018130 187 0.064
multicellular organism reproduction GO:0032504 819 0.064
cell fate commitment GO:0045165 139 0.063
Worm
aromatic compound biosynthetic process GO:0019438 192 0.062
response to endogenous stimulus GO:0009719 33 0.062
Mouse Rat
sensory organ morphogenesis GO:0090596 2 0.062
developmental growth GO:0048589 412 0.062
nucleobase containing compound metabolic process GO:0006139 406 0.061
response to wounding GO:0009611 4 0.061
secretion by cell GO:0032940 138 0.061
carbohydrate derivative metabolic process GO:1901135 141 0.061
negative regulation of cell communication GO:0010648 61 0.059
Mouse
cellular macromolecule biosynthetic process GO:0034645 247 0.059
small molecule metabolic process GO:0044281 186 0.059
Mouse Rat
protein metabolic process GO:0019538 422 0.058
regulation of signal transduction GO:0009966 135 0.058
Mouse
lipid storage GO:0019915 565 0.058
Fly
cell projection organization GO:0030030 231 0.057
Fly
cellular response to organic substance GO:0071310 119 0.056
Rat
cellular protein metabolic process GO:0044267 279 0.056
positive regulation of response to stimulus GO:0048584 55 0.056
system process GO:0003008 136 0.056
Fly
homeostatic process GO:0042592 51 0.055
Mouse Rat
memory GO:0007613 3 0.055
positive regulation of cellular biosynthetic process GO:0031328 109 0.055
neuron development GO:0048666 199 0.055
Fly
regulation of catalytic activity GO:0050790 78 0.055
regulation of response to stimulus GO:0048583 243 0.055
Mouse Rat
ion transmembrane transport GO:0034220 91 0.055
cellular response to chemical stimulus GO:0070887 129 0.054
Rat
negative regulation of vulval development GO:0040027 206 0.053
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.053
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.053
regulation of rna biosynthetic process GO:2001141 165 0.053
lipid localization GO:0010876 573 0.053
Fly
protein phosphorylation GO:0006468 85 0.053
development of primary sexual characteristics GO:0045137 840 0.052
positive regulation of growth GO:0045927 369 0.052
negative regulation of gene expression GO:0010629 217 0.052
pole plasm assembly GO:0007315 2 0.052
cell surface receptor signaling pathway GO:0007166 149 0.052
detection of external stimulus GO:0009581 4 0.052
gamete generation GO:0007276 461 0.051
post embryonic organ development GO:0048569 336 0.050
sexual reproduction GO:0019953 546 0.050
aging GO:0007568 812 0.050
reproductive structure development GO:0048608 850 0.050
apoptotic process GO:0006915 478 0.050
Mouse Worm
regulation of cellular biosynthetic process GO:0031326 189 0.050
epithelial cell proliferation GO:0050673 1 0.049
regulation of locomotion GO:0040012 161 0.048
positive regulation of gene expression GO:0010628 112 0.048
Human
regulation of cellular catabolic process GO:0031329 51 0.048
Mouse Rat
positive regulation of developmental process GO:0051094 408 0.047
positive regulation of cellular metabolic process GO:0031325 178 0.047
Mouse Rat
response to nutrient levels GO:0031667 35 0.047
Mouse Fly
muscle cell differentiation GO:0042692 171 0.047
cellular response to stress GO:0033554 162 0.047
Mouse Rat Fly
macromolecular complex subunit organization GO:0043933 320 0.047
Mouse Rat
response to external stimulus GO:0009605 289 0.046
Mouse Fly
organ development GO:0048513 1102 0.045
transmembrane transport GO:0055085 110 0.045
monocarboxylic acid metabolic process GO:0032787 22 0.044
Mouse Rat
regulation of biosynthetic process GO:0009889 189 0.044
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.043
cell cycle GO:0007049 526 0.043
cell motility GO:0048870 313 0.043
negative regulation of nematode larval development GO:0061064 208 0.042
negative regulation of cellular process GO:0048523 239 0.042
lipid metabolic process GO:0006629 77 0.042
Mouse Rat Fly
organonitrogen compound catabolic process GO:1901565 90 0.042
asymmetric protein localization GO:0008105 35 0.042
regulation of lipid biosynthetic process GO:0046890 1 0.041
regulation of cellular protein metabolic process GO:0032268 75 0.041
nitrogen compound transport GO:0071705 49 0.041
rna localization GO:0006403 3 0.039
cellular component movement GO:0006928 388 0.039
Fly
regulation of multicellular organismal development GO:2000026 317 0.039
regulation of cellular ketone metabolic process GO:0010565 3 0.039
positive regulation of jnk cascade GO:0046330 3 0.039
multicellular organismal reproductive behavior GO:0033057 384 0.039
regulation of cellular component organization GO:0051128 248 0.039
Fly
body morphogenesis GO:0010171 620 0.038
cellular ketone metabolic process GO:0042180 14 0.038
positive regulation of protein kinase activity GO:0045860 18 0.038
gonad development GO:0008406 840 0.037
receptor mediated endocytosis GO:0006898 715 0.037
negative regulation of biosynthetic process GO:0009890 65 0.037
protein localization GO:0008104 205 0.037
regulation of developmental process GO:0050793 684 0.037
rna metabolic process GO:0016070 228 0.037
carboxylic acid metabolic process GO:0019752 34 0.037
Mouse Rat
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.037
meiotic cell cycle GO:0051321 335 0.036
protein complex subunit organization GO:0071822 280 0.036
Rat
purine nucleotide catabolic process GO:0006195 75 0.036
small molecule catabolic process GO:0044282 9 0.035
anion transport GO:0006820 30 0.035
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.035
positive regulation of stress activated mapk cascade GO:0032874 3 0.035
response to extracellular stimulus GO:0009991 38 0.035
Mouse Fly
regulation of cellular amine metabolic process GO:0033238 0 0.035
muscle structure development GO:0061061 191 0.035
single organism membrane organization GO:0044802 35 0.035
protein oligomerization GO:0051259 4 0.034
Rat
cellular component assembly involved in morphogenesis GO:0010927 183 0.034
cell type specific apoptotic process GO:0097285 4 0.034
calcium mediated signaling GO:0019722 3 0.034
response to temperature stimulus GO:0009266 66 0.034
Rat
aromatic compound catabolic process GO:0019439 116 0.033
cellular component morphogenesis GO:0032989 318 0.033
Fly
macromolecule modification GO:0043412 218 0.033
head development GO:0060322 1 0.033
intraspecies interaction between organisms GO:0051703 3 0.032
regulation of cellular amino acid metabolic process GO:0006521 0 0.032
actin cytoskeleton organization GO:0030036 184 0.032
nucleic acid metabolic process GO:0090304 299 0.032
positive regulation of neuron projection development GO:0010976 4 0.032
regulation of cytoplasmic transport GO:1903649 3 0.032
positive regulation of biosynthetic process GO:0009891 109 0.032
regulation of ion transport GO:0043269 39 0.031
regulation of gene expression GO:0010468 366 0.031
Human
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.031
germ cell development GO:0007281 351 0.031
protein catabolic process GO:0030163 162 0.031
cellular amine metabolic process GO:0044106 15 0.031
localization of cell GO:0051674 313 0.031
negative regulation of nucleic acid templated transcription GO:1903507 53 0.031
positive regulation of cell projection organization GO:0031346 4 0.031
positive regulation of nucleic acid templated transcription GO:1903508 102 0.031
cellular nitrogen compound biosynthetic process GO:0044271 192 0.031
canonical wnt signaling pathway GO:0060070 3 0.030
vulval development GO:0040025 333 0.030
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.030
negative regulation of transcription from rna polymerase ii promoter GO:0000122 45 0.029
regulation of multi organism process GO:0043900 69 0.029
oviposition GO:0018991 364 0.029
oocyte axis specification GO:0007309 2 0.028
amine metabolic process GO:0009308 15 0.028
ras protein signal transduction GO:0007265 31 0.028
negative regulation of response to stimulus GO:0048585 73 0.028
Mouse Rat
organic hydroxy compound metabolic process GO:1901615 25 0.028
stress activated mapk cascade GO:0051403 10 0.027
molting cycle GO:0042303 281 0.027
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.027
regulation of rna metabolic process GO:0051252 173 0.027
secretion GO:0046903 147 0.027
single organism behavior GO:0044708 83 0.026
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.026
inductive cell migration GO:0040039 145 0.026
regulation of growth GO:0040008 409 0.026
Fly
negative regulation of multicellular organismal process GO:0051241 236 0.026
striated muscle cell differentiation GO:0051146 158 0.026
cellular lipid metabolic process GO:0044255 40 0.026
Mouse
negative regulation of cellular metabolic process GO:0031324 95 0.026
reproductive behavior GO:0019098 387 0.026
response to starvation GO:0042594 26 0.025
Mouse Fly
small gtpase mediated signal transduction GO:0007264 32 0.025
response to transforming growth factor beta GO:0071559 13 0.025
regulation of behavior GO:0050795 97 0.025
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.025
regulation of reproductive process GO:2000241 66 0.025
nucleic acid templated transcription GO:0097659 169 0.025
protein modification process GO:0036211 207 0.025
cell cycle process GO:0022402 482 0.025
negative regulation of signaling GO:0023057 61 0.025
Mouse
regulation of phosphorylation GO:0042325 45 0.024
response to inorganic substance GO:0010035 50 0.024
Mouse Rat
negative regulation of post embryonic development GO:0048581 208 0.024
organic acid catabolic process GO:0016054 3 0.024
negative regulation of rna biosynthetic process GO:1902679 53 0.024
glycosyl compound catabolic process GO:1901658 79 0.024
organonitrogen compound biosynthetic process GO:1901566 44 0.023
regulation of catabolic process GO:0009894 57 0.023
Mouse Rat
establishment or maintenance of cell polarity GO:0007163 63 0.023
Fly
amine catabolic process GO:0009310 1 0.023
positive regulation of phosphorylation GO:0042327 27 0.023
developmental maturation GO:0021700 26 0.023
actin filament based process GO:0030029 191 0.023
inorganic ion transmembrane transport GO:0098660 54 0.023
regulation of cell proliferation GO:0042127 105 0.023
Rat Worm
organelle assembly GO:0070925 214 0.023
cellular nitrogen compound catabolic process GO:0044270 119 0.023
nucleotide metabolic process GO:0009117 108 0.023
positive regulation of phosphate metabolic process GO:0045937 56 0.023
reproductive system development GO:0061458 850 0.023
positive regulation of protein metabolic process GO:0051247 45 0.023
positive regulation of neurogenesis GO:0050769 4 0.022
regulation of programmed cell death GO:0043067 50 0.022
Mouse
cell maturation GO:0048469 26 0.022
membrane organization GO:0061024 135 0.022
proteolysis GO:0006508 61 0.022
negative regulation of transcription dna templated GO:0045892 53 0.022
muscle system process GO:0003012 43 0.022
negative regulation of rna metabolic process GO:0051253 53 0.021
regulation of macromolecule biosynthetic process GO:0010556 189 0.021
nucleoside triphosphate metabolic process GO:0009141 87 0.021
regulation of developmental growth GO:0048638 389 0.021
posttranscriptional regulation of gene expression GO:0010608 166 0.021
cellular amino acid metabolic process GO:0006520 15 0.021
translation GO:0006412 37 0.021
axon development GO:0061564 163 0.021
Fly
long term memory GO:0007616 2 0.021
stress activated protein kinase signaling cascade GO:0031098 10 0.021
cellular response to extracellular stimulus GO:0031668 16 0.021
Mouse Fly
organophosphate metabolic process GO:0019637 125 0.021
oocyte construction GO:0007308 2 0.021
regulation of vulval development GO:0040028 248 0.021
regulation of oviposition GO:0046662 43 0.021
regeneration GO:0031099 4 0.021
ribose phosphate metabolic process GO:0019693 99 0.021
regulation of multicellular organism growth GO:0040014 373 0.020
regulation of lipid metabolic process GO:0019216 4 0.020
Mouse Rat
pronuclear migration GO:0035046 51 0.020
positive regulation of multicellular organism growth GO:0040018 352 0.020
peptidyl tyrosine phosphorylation GO:0018108 2 0.020
sex differentiation GO:0007548 909 0.020
regulation of synaptic plasticity GO:0048167 1 0.020
male sex differentiation GO:0046661 86 0.020
actomyosin structure organization GO:0031032 154 0.020
neuromuscular junction development GO:0007528 2 0.019
positive regulation of neuron differentiation GO:0045666 4 0.019
cellular response to external stimulus GO:0071496 16 0.019
Mouse Fly
ribonucleotide metabolic process GO:0009259 99 0.019
carboxylic acid biosynthetic process GO:0046394 21 0.019
signal release GO:0023061 28 0.019
regulation of neurotransmitter levels GO:0001505 36 0.019
epithelium development GO:0060429 68 0.019
protein complex biogenesis GO:0070271 186 0.019
Rat
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 2 0.019
regulation of nucleocytoplasmic transport GO:0046822 3 0.018
response to oxygen containing compound GO:1901700 44 0.018
Mouse Rat
regulation of post embryonic development GO:0048580 260 0.018
cell part morphogenesis GO:0032990 152 0.018
Fly
regulation of calcium ion transport GO:0051924 3 0.018
enzyme linked receptor protein signaling pathway GO:0007167 50 0.018
synapse organization GO:0050808 24 0.018
cell proliferation GO:0008283 116 0.018
Rat Worm
positive regulation of transferase activity GO:0051347 21 0.018
regulation of mapk cascade GO:0043408 23 0.018
protein complex assembly GO:0006461 186 0.018
Rat
regulation of organelle organization GO:0033043 164 0.018
response to other organism GO:0051707 101 0.017
multi multicellular organism process GO:0044706 390 0.017
nucleoside phosphate metabolic process GO:0006753 108 0.017
negative regulation of macromolecule metabolic process GO:0010605 229 0.017
lipid oxidation GO:0034440 1 0.017
Mouse
synaptic growth at neuromuscular junction GO:0051124 1 0.017
digestive system development GO:0055123 122 0.017
cellular response to growth factor stimulus GO:0071363 18 0.017
gene silencing by rna GO:0031047 143 0.017
neuromuscular process GO:0050905 1 0.017
response to acid chemical GO:0001101 4 0.017
cellular homeostasis GO:0019725 22 0.017
adult behavior GO:0030534 3 0.016
cell cell signaling GO:0007267 118 0.016
intracellular transport GO:0046907 77 0.016
wnt signaling pathway GO:0016055 27 0.016
nucleus localization GO:0051647 55 0.016
regulation of cell death GO:0010941 65 0.016
Mouse
immune response GO:0006955 192 0.016
social behavior GO:0035176 3 0.016
regulation of hormone secretion GO:0046883 2 0.016
myofibril assembly GO:0030239 154 0.016
positive regulation of cell communication GO:0010647 69 0.016
positive regulation of cell morphogenesis involved in differentiation GO:0010770 4 0.016
chromatin remodeling GO:0006338 2 0.016
pigmentation GO:0043473 2 0.016
cellular response to abiotic stimulus GO:0071214 4 0.016
locomotory behavior GO:0007626 40 0.016
heterocycle catabolic process GO:0046700 119 0.016
organic cyclic compound catabolic process GO:1901361 119 0.015
tissue development GO:0009888 112 0.015
adult locomotory behavior GO:0008344 1 0.015
mapk cascade GO:0000165 31 0.015
neuron differentiation GO:0030182 217 0.015
Fly
peptide hormone secretion GO:0030072 2 0.015
organic substance transport GO:0071702 113 0.015
Rat
posttranscriptional gene silencing by rna GO:0035194 143 0.015
single organism intracellular transport GO:1902582 70 0.015
muscle cell development GO:0055001 158 0.015
genitalia development GO:0048806 741 0.015
cation transmembrane transport GO:0098655 59 0.015
regulation of response to stress GO:0080134 28 0.015
ribonucleoside catabolic process GO:0042454 77 0.015
regulation of response to wounding GO:1903034 1 0.015
regulation of cellular carbohydrate metabolic process GO:0010675 2 0.015
Rat
regulation of meiotic cell cycle GO:0051445 136 0.014
oocyte differentiation GO:0009994 45 0.014
carbohydrate derivative catabolic process GO:1901136 82 0.014
peptidyl amino acid modification GO:0018193 58 0.014
membrane invagination GO:0010324 98 0.014
generation of precursor metabolites and energy GO:0006091 18 0.014
Rat
negative regulation of protein metabolic process GO:0051248 27 0.014
myosin filament assembly GO:0031034 138 0.014
regionalization GO:0003002 31 0.014
neuron projection morphogenesis GO:0048812 114 0.014
Fly
purine ribonucleoside metabolic process GO:0046128 92 0.014
multi organism behavior GO:0051705 389 0.014
gene silencing GO:0016458 143 0.014
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 9 0.014
neurological system process GO:0050877 53 0.014
response to oxygen levels GO:0070482 22 0.014
Rat
neuron projection development GO:0031175 187 0.014
Fly
anterior posterior pattern specification GO:0009952 27 0.014
response to mechanical stimulus GO:0009612 28 0.014
positive regulation of transport GO:0051050 32 0.014
cellular macromolecule localization GO:0070727 75 0.014
regulation of transferase activity GO:0051338 31 0.013
cell division GO:0051301 262 0.013
Worm
asymmetric cell division GO:0008356 36 0.013
hormone metabolic process GO:0042445 3 0.013
cell morphogenesis involved in differentiation GO:0000904 112 0.013
Fly
organelle localization GO:0051640 127 0.013
multicellular organism growth GO:0035264 385 0.013
regulation of apoptotic process GO:0042981 36 0.013
Mouse
cgmp metabolic process GO:0046068 2 0.013
lipid biosynthetic process GO:0008610 28 0.013
Mouse
cellular macromolecular complex assembly GO:0034622 184 0.013
neurotransmitter transport GO:0006836 32 0.012
positive regulation of calcium ion transport GO:0051928 1 0.012
purine containing compound catabolic process GO:0072523 75 0.012
regulation of ras protein signal transduction GO:0046578 41 0.012
regulation of cellular response to stress GO:0080135 19 0.012
purine nucleotide metabolic process GO:0006163 95 0.012
positive regulation of chromosome organization GO:2001252 2 0.012
cellular response to nitrogen compound GO:1901699 24 0.012
Rat
macroautophagy GO:0016236 11 0.012
negative regulation of cell cycle GO:0045786 53 0.012
pattern specification process GO:0007389 59 0.012
ribonucleoprotein complex assembly GO:0022618 4 0.012
regulation of protein localization GO:0032880 50 0.012
detection of abiotic stimulus GO:0009582 4 0.012
regulation of protein modification process GO:0031399 46 0.012
neuron apoptotic process GO:0051402 4 0.012
establishment of organelle localization GO:0051656 123 0.012
positive regulation of signal transduction GO:0009967 40 0.012
regulation of jun kinase activity GO:0043506 3 0.012
nucleobase containing small molecule metabolic process GO:0055086 115 0.012
regulation of purine nucleotide metabolic process GO:1900542 37 0.012
positive regulation of intracellular transport GO:0032388 2 0.012
regulation of carbohydrate metabolic process GO:0006109 2 0.012
Rat
rna interference GO:0016246 137 0.011
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 16 0.011
small molecule biosynthetic process GO:0044283 38 0.011
cellular protein localization GO:0034613 75 0.011
fatty acid metabolic process GO:0006631 16 0.011
Mouse
cellular protein complex assembly GO:0043623 178 0.011
response to osmotic stress GO:0006970 29 0.011
g protein coupled receptor signaling pathway GO:0007186 46 0.011
immune response regulating signaling pathway GO:0002764 1 0.011
hermaphrodite genitalia development GO:0040035 734 0.011
single organism biosynthetic process GO:0044711 91 0.011
Mouse
negative regulation of signal transduction GO:0009968 60 0.011
Mouse
nucleoside catabolic process GO:0009164 78 0.011
establishment of rna localization GO:0051236 3 0.011
chemical homeostasis GO:0048878 29 0.011
Mouse Rat
striated muscle myosin thick filament assembly GO:0071688 138 0.011
positive regulation of kinase activity GO:0033674 19 0.011
organ morphogenesis GO:0009887 67 0.011
taxis GO:0042330 128 0.011
Fly
organophosphate catabolic process GO:0046434 81 0.011
learning or memory GO:0007611 27 0.011
cytosolic calcium ion homeostasis GO:0051480 2 0.011
cellular ion homeostasis GO:0006873 11 0.011
axis specification GO:0009798 23 0.011
regulation of stem cell differentiation GO:2000736 1 0.011
posttranscriptional gene silencing GO:0016441 143 0.011
cell recognition GO:0008037 85 0.011
carbohydrate biosynthetic process GO:0016051 4 0.011
ion homeostasis GO:0050801 21 0.011
Rat
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.011
regulation of protein serine threonine kinase activity GO:0071900 18 0.011
regulation of transport GO:0051049 91 0.011
Rat
positive regulation of ion transport GO:0043270 10 0.011
regulation of kinase activity GO:0043549 29 0.011
ribonucleoside metabolic process GO:0009119 98 0.010
innate immune response GO:0045087 190 0.010
regulation of immune response GO:0050776 10 0.010
positive regulation of cellular catabolic process GO:0031331 35 0.010
Mouse Rat
apoptotic cell clearance GO:0043277 111 0.010
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.010
purine nucleoside metabolic process GO:0042278 92 0.010

aak-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.106
inherited metabolic disorder DOID:655 0 0.022
disease of anatomical entity DOID:7 0 0.015