Caenorhabditis elegans

141 known processes

cdk-1 (CELE_T05G5.3)

Protein CDK-1

cdk-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development ending in birth or egg hatching GO:0009792 2992 0.531
regulation of biosynthetic process GO:0009889 189 0.527
Yeast
single fertilization GO:0007338 61 0.424
protein metabolic process GO:0019538 422 0.397
embryo development GO:0009790 3052 0.389
regulation of primary metabolic process GO:0080090 292 0.383
positive regulation of metabolic process GO:0009893 187 0.350
positive regulation of macromolecule metabolic process GO:0010604 149 0.313
gonad development GO:0008406 840 0.287
female meiotic division GO:0007143 17 0.285
multicellular organism reproduction GO:0032504 819 0.281
multi organism reproductive process GO:0044703 867 0.273
positive regulation of cellular process GO:0048522 332 0.266
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.254
meiotic nuclear division GO:0007126 300 0.254
regulation of metabolic process GO:0019222 478 0.251
sex differentiation GO:0007548 909 0.248
pronuclear migration GO:0035046 51 0.245
single organism reproductive process GO:0044702 1196 0.239
microtubule based process GO:0007017 182 0.235
Yeast
regulation of cellular metabolic process GO:0031323 305 0.235
sexual reproduction GO:0019953 546 0.226
regulation of gene expression GO:0010468 366 0.225
Yeast Worm
nucleobase containing compound metabolic process GO:0006139 406 0.225
Yeast
genitalia development GO:0048806 741 0.223
programmed cell death GO:0012501 500 0.216
Human
regulation of macromolecule biosynthetic process GO:0010556 189 0.210
Yeast
cell fate commitment GO:0045165 139 0.210
Fly
regulation of transcription dna templated GO:0006355 164 0.206
Yeast
fertilization GO:0009566 63 0.190
oviposition GO:0018991 364 0.187
post embryonic organ development GO:0048569 336 0.187
cell cycle GO:0007049 526 0.187
vesicle mediated transport GO:0016192 852 0.185
Yeast
apoptotic process GO:0006915 478 0.185
Human
organelle organization GO:0006996 783 0.183
organelle localization GO:0051640 127 0.183
post embryonic development GO:0009791 2152 0.179
Worm
single organism localization GO:1902578 518 0.179
cellular biosynthetic process GO:0044249 315 0.175
Yeast
establishment of localization in cell GO:0051649 318 0.165
establishment of localization GO:0051234 1171 0.160
catabolic process GO:0009056 318 0.153
Yeast
cell death GO:0008219 547 0.145
Human
transport GO:0006810 1093 0.144
Yeast
regulation of macromolecule metabolic process GO:0060255 421 0.143
negative regulation of developmental process GO:0051093 227 0.140
cellular component biogenesis GO:0044085 297 0.138
Yeast
multi organism reproductive behavior GO:0044705 387 0.138
negative regulation of biological process GO:0048519 567 0.137
Human Yeast Mouse Worm Fly
chromosome organization GO:0051276 104 0.133
Yeast
developmental process involved in reproduction GO:0003006 1165 0.132
multicellular organismal reproductive behavior GO:0033057 384 0.131
gene expression GO:0010467 412 0.130
Yeast Worm
reproductive behavior GO:0019098 387 0.130
macromolecular complex subunit organization GO:0043933 320 0.129
Yeast
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.127
Yeast
gamete generation GO:0007276 461 0.125
macromolecule localization GO:0033036 771 0.124
Human Yeast Fly
aging GO:0007568 812 0.123
phosphorus metabolic process GO:0006793 232 0.118
multi multicellular organism process GO:0044706 390 0.116
transcription from rna polymerase ii promoter GO:0006366 149 0.116
Yeast
regulation of multicellular organismal process GO:0051239 726 0.114
Worm
development of primary sexual characteristics GO:0045137 840 0.112
macromolecule biosynthetic process GO:0009059 250 0.109
Yeast
regulation of rna biosynthetic process GO:2001141 165 0.109
Yeast
protein modification process GO:0036211 207 0.107
organ development GO:0048513 1102 0.107
organic substance biosynthetic process GO:1901576 323 0.107
Yeast
mitotic spindle organization GO:0007052 81 0.103
hermaphrodite genitalia development GO:0040035 734 0.103
nervous system development GO:0007399 253 0.101
Fly
cellular protein metabolic process GO:0044267 279 0.099
endocytosis GO:0006897 819 0.097
regulation of developmental process GO:0050793 684 0.097
Worm
female gamete generation GO:0007292 254 0.096
cellular catabolic process GO:0044248 199 0.094
Yeast
phosphate containing compound metabolic process GO:0006796 232 0.093
purine containing compound catabolic process GO:0072523 75 0.093
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.090
Yeast
single organism cellular localization GO:1902580 72 0.089
cellular localization GO:0051641 360 0.089
protein localization GO:0008104 205 0.089
Human Yeast Fly
multi organism behavior GO:0051705 389 0.088
regulation of nematode larval development GO:0061062 260 0.087
negative regulation of nematode larval development GO:0061064 208 0.087
purine nucleoside triphosphate metabolic process GO:0009144 87 0.087
regulation of biological quality GO:0065008 741 0.087
transcription dna templated GO:0006351 168 0.086
Yeast
death GO:0016265 547 0.085
Human
behavior GO:0007610 527 0.085
purine ribonucleotide metabolic process GO:0009150 95 0.084
regulation of vulval development GO:0040028 248 0.083
regulation of multicellular organismal development GO:2000026 317 0.083
body morphogenesis GO:0010171 620 0.082
Worm
positive regulation of cellular metabolic process GO:0031325 178 0.081
macromolecule modification GO:0043412 218 0.080
negative regulation of vulval development GO:0040027 206 0.080
cellular component assembly GO:0022607 293 0.080
Yeast
rna localization GO:0006403 3 0.079
positive regulation of developmental process GO:0051094 408 0.079
Worm
aromatic compound catabolic process GO:0019439 116 0.079
Yeast
regulation of cellular component organization GO:0051128 248 0.078
positive regulation of catalytic activity GO:0043085 59 0.077
positive regulation of catabolic process GO:0009896 38 0.077
Yeast
cellular nitrogen compound biosynthetic process GO:0044271 192 0.074
Yeast
purine nucleoside catabolic process GO:0006152 75 0.074
negative regulation of macromolecule metabolic process GO:0010605 229 0.074
Yeast
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.074
Yeast
nucleoside triphosphate catabolic process GO:0009143 72 0.073
cellular macromolecule biosynthetic process GO:0034645 247 0.073
Yeast
organic cyclic compound biosynthetic process GO:1901362 195 0.072
Yeast
maintenance of location GO:0051235 580 0.072
mitotic sister chromatid segregation GO:0000070 38 0.072
heterocycle biosynthetic process GO:0018130 187 0.072
Yeast
nucleoside catabolic process GO:0009164 78 0.071
glycosyl compound catabolic process GO:1901658 79 0.071
glycosyl compound metabolic process GO:1901657 100 0.071
reproductive system development GO:0061458 850 0.071
positive regulation of multicellular organismal process GO:0051240 417 0.071
Worm
guanosine containing compound metabolic process GO:1901068 49 0.070
growth GO:0040007 562 0.069
Yeast Worm
determination of adult lifespan GO:0008340 812 0.069
multicellular organismal reproductive process GO:0048609 815 0.066
cell development GO:0048468 696 0.065
cellular nitrogen compound catabolic process GO:0044270 119 0.065
Yeast
mitotic cell cycle process GO:1903047 194 0.064
negative regulation of multicellular organismal process GO:0051241 236 0.064
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.064
meiotic chromosome segregation GO:0045132 139 0.064
oogenesis GO:0048477 229 0.063
purine ribonucleoside catabolic process GO:0046130 75 0.063
multicellular organism growth GO:0035264 385 0.062
Worm
regulation of rna metabolic process GO:0051252 173 0.062
Yeast
germ cell development GO:0007281 351 0.062
membrane organization GO:0061024 135 0.061
nucleobase containing compound biosynthetic process GO:0034654 184 0.061
Yeast
ribonucleotide catabolic process GO:0009261 75 0.060
regulation of post embryonic development GO:0048580 260 0.060
lipid localization GO:0010876 573 0.060
protein complex subunit organization GO:0071822 280 0.060
Yeast
nucleoside triphosphate metabolic process GO:0009141 87 0.059
muscle structure development GO:0061061 191 0.059
vulval development GO:0040025 333 0.059
purine nucleotide catabolic process GO:0006195 75 0.059
lipid storage GO:0019915 565 0.058
aromatic compound biosynthetic process GO:0019438 192 0.058
Yeast
guanosine containing compound catabolic process GO:1901069 48 0.058
multicellular organismal aging GO:0010259 812 0.057
oocyte differentiation GO:0009994 45 0.057
negative regulation of metabolic process GO:0009892 240 0.056
Yeast
ribonucleoside triphosphate catabolic process GO:0009203 72 0.056
cellular protein modification process GO:0006464 207 0.056
cellular response to dna damage stimulus GO:0006974 41 0.056
Yeast Mouse Fly
nucleobase containing compound catabolic process GO:0034655 114 0.056
Yeast
organelle fission GO:0048285 363 0.055
epithelium development GO:0060429 68 0.054
Human
biosynthetic process GO:0009058 323 0.054
Yeast
regulation of protein metabolic process GO:0051246 81 0.054
regulation of nitrogen compound metabolic process GO:0051171 222 0.053
Yeast
organic cyclic compound catabolic process GO:1901361 119 0.053
Yeast
digestive system development GO:0055123 122 0.052
negative regulation of cellular process GO:0048523 239 0.052
Human Yeast Mouse Worm Fly
single organism transport GO:0044765 447 0.052
tissue development GO:0009888 112 0.051
Human
ribose phosphate metabolic process GO:0019693 99 0.051
positive regulation of developmental growth GO:0048639 354 0.051
Worm
spindle organization GO:0007051 92 0.051
regulation of catalytic activity GO:0050790 78 0.051
cytoskeleton organization GO:0007010 339 0.051
Yeast
posttranscriptional regulation of gene expression GO:0010608 166 0.050
Worm
gtp catabolic process GO:0006184 46 0.050
organic substance catabolic process GO:1901575 294 0.050
Yeast
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.049
regulation of cellular catabolic process GO:0031329 51 0.049
Yeast
carbohydrate derivative metabolic process GO:1901135 141 0.049
regulation of growth GO:0040008 409 0.049
Yeast Worm
purine nucleoside triphosphate catabolic process GO:0009146 72 0.048
ribonucleoside catabolic process GO:0042454 77 0.048
signaling GO:0023052 401 0.047
cellular response to stress GO:0033554 162 0.046
Yeast Mouse Fly
gtp metabolic process GO:0046039 46 0.046
regulation of catabolic process GO:0009894 57 0.045
Yeast
head development GO:0060322 1 0.045
regulation of multicellular organism growth GO:0040014 373 0.045
Worm
neurogenesis GO:0022008 236 0.045
Fly
meiotic cell cycle process GO:1903046 170 0.045
Yeast
nucleoside phosphate metabolic process GO:0006753 108 0.045
axon development GO:0061564 163 0.044
nucleotide metabolic process GO:0009117 108 0.044
generation of neurons GO:0048699 235 0.044
Fly
positive regulation of phosphorus metabolic process GO:0010562 56 0.044
regulation of cell communication GO:0010646 176 0.043
regulation of molecular function GO:0065009 89 0.043
nucleic acid metabolic process GO:0090304 299 0.043
Yeast
nucleus localization GO:0051647 55 0.043
negative regulation of cellular component organization GO:0051129 33 0.042
Yeast
protein phosphorylation GO:0006468 85 0.042
heterocycle catabolic process GO:0046700 119 0.041
Yeast
nucleic acid templated transcription GO:0097659 169 0.040
Yeast
regulation of mitotic cell cycle GO:0007346 76 0.040
Yeast Mouse Worm Fly
ribonucleoside triphosphate metabolic process GO:0009199 87 0.040
macromolecular complex assembly GO:0065003 193 0.039
regulation of response to stimulus GO:0048583 243 0.039
Yeast
protein complex biogenesis GO:0070271 186 0.038
positive regulation of multicellular organism growth GO:0040018 352 0.038
Worm
dna metabolic process GO:0006259 74 0.038
Yeast
rna metabolic process GO:0016070 228 0.037
Yeast
regulation of gene expression epigenetic GO:0040029 163 0.037
localization of cell GO:0051674 313 0.036
regulation of phosphorus metabolic process GO:0051174 81 0.036
receptor mediated endocytosis GO:0006898 715 0.036
cellular macromolecular complex assembly GO:0034622 184 0.036
nucleotide catabolic process GO:0009166 77 0.036
dna conformation change GO:0071103 11 0.036
regulation of cellular biosynthetic process GO:0031326 189 0.036
Yeast
cell cycle process GO:0022402 482 0.036
ion transport GO:0006811 113 0.036
tube development GO:0035295 126 0.036
establishment of organelle localization GO:0051656 123 0.034
establishment of mitotic spindle orientation GO:0000132 28 0.034
neuron projection development GO:0031175 187 0.033
microtubule polymerization or depolymerization GO:0031109 22 0.033
microtubule cytoskeleton organization involved in mitosis GO:1902850 12 0.033
organonitrogen compound catabolic process GO:1901565 90 0.033
ribonucleoside metabolic process GO:0009119 98 0.033
single organism organelle organization GO:1902589 501 0.033
positive regulation of growth GO:0045927 369 0.032
Worm
positive regulation of molecular function GO:0044093 61 0.032
protein complex assembly GO:0006461 186 0.032
positive regulation of phosphate metabolic process GO:0045937 56 0.031
cell projection organization GO:0030030 231 0.031
skeletal muscle organ development GO:0060538 3 0.031
regulation of mitotic spindle organization GO:0060236 3 0.031
single organism catabolic process GO:0044712 129 0.031
Yeast
regulation of nucleic acid templated transcription GO:1903506 165 0.031
Yeast
nucleoside phosphate catabolic process GO:1901292 77 0.031
rna biosynthetic process GO:0032774 169 0.030
Yeast
ribonucleotide metabolic process GO:0009259 99 0.030
nucleus organization GO:0006997 38 0.030
organonitrogen compound metabolic process GO:1901564 151 0.030
nuclear migration GO:0007097 54 0.030
regulation of cell differentiation GO:0045595 81 0.029
purine ribonucleotide catabolic process GO:0009154 75 0.029
positive regulation of protein metabolic process GO:0051247 45 0.029
organophosphate catabolic process GO:0046434 81 0.029
defense response GO:0006952 296 0.029
sister chromatid segregation GO:0000819 46 0.029
protein catabolic process GO:0030163 162 0.029
male gamete generation GO:0048232 41 0.029
Fly
locomotion GO:0040011 1634 0.029
nucleoside metabolic process GO:0009116 99 0.029
single organism signaling GO:0044700 401 0.029
single organism biosynthetic process GO:0044711 91 0.028
Yeast
purine ribonucleoside metabolic process GO:0046128 92 0.027
cell division GO:0051301 262 0.027
gene silencing by rna GO:0031047 143 0.027
negative regulation of gene expression GO:0010629 217 0.027
Yeast
purine nucleotide metabolic process GO:0006163 95 0.027
regulation of cell cycle GO:0051726 194 0.027
establishment of cell polarity GO:0030010 46 0.026
cellular protein complex assembly GO:0043623 178 0.026
signal transduction GO:0007165 317 0.026
endomembrane system organization GO:0010256 22 0.025
cellular macromolecule localization GO:0070727 75 0.025
Human
organelle assembly GO:0070925 214 0.025
developmental growth GO:0048589 412 0.024
Worm
muscle tissue development GO:0060537 1 0.024
organic substance transport GO:0071702 113 0.024
gene silencing GO:0016458 143 0.024
posttranscriptional gene silencing GO:0016441 143 0.023
regulation of cellular protein metabolic process GO:0032268 75 0.023
establishment of spindle localization GO:0051293 51 0.023
macromolecule catabolic process GO:0009057 202 0.023
Yeast
cellular component movement GO:0006928 388 0.023
oocyte development GO:0048599 44 0.022
digestive tract development GO:0048565 122 0.022
negative regulation of post embryonic development GO:0048581 208 0.022
cytokinesis GO:0000910 80 0.022
secretion by cell GO:0032940 138 0.022
reproductive structure development GO:0048608 850 0.022
mitotic spindle stabilization GO:0043148 2 0.022
positive regulation of cellular catabolic process GO:0031331 35 0.022
Yeast
negative regulation of cell cycle GO:0045786 53 0.022
Yeast Mouse Worm Fly
chromosome condensation GO:0030261 6 0.021
establishment or maintenance of cell polarity GO:0007163 63 0.021
neuron differentiation GO:0030182 217 0.021
peptidyl amino acid modification GO:0018193 58 0.021
Human Yeast
male sex differentiation GO:0046661 86 0.020
tube morphogenesis GO:0035239 79 0.020
negative regulation of biosynthetic process GO:0009890 65 0.020
Yeast
response to chemical GO:0042221 356 0.020
cytoskeleton dependent cytokinesis GO:0061640 35 0.020
muscle cell differentiation GO:0042692 171 0.020
secretion GO:0046903 147 0.020
regulation of developmental growth GO:0048638 389 0.020
Worm
negative regulation of transcription dna templated GO:0045892 53 0.020
Yeast
establishment of mitotic spindle localization GO:0040001 41 0.020
chromosome segregation GO:0007059 180 0.020
Yeast
carbohydrate derivative catabolic process GO:1901136 82 0.019
response to abiotic stimulus GO:0009628 152 0.019
small molecule metabolic process GO:0044281 186 0.019
organophosphate metabolic process GO:0019637 125 0.019
cell migration GO:0016477 306 0.019
negative regulation of gene expression epigenetic GO:0045814 2 0.019
purine nucleoside metabolic process GO:0042278 92 0.019
nucleobase containing small molecule metabolic process GO:0055086 115 0.019
muscle organ development GO:0007517 26 0.018
cellular component morphogenesis GO:0032989 318 0.018
cell recognition GO:0008037 85 0.018
negative regulation of rna metabolic process GO:0051253 53 0.018
Yeast
negative regulation of neurogenesis GO:0050768 4 0.018
purine containing compound metabolic process GO:0072521 95 0.018
regulation of meiotic cell cycle GO:0051445 136 0.018
posttranscriptional gene silencing by rna GO:0035194 143 0.017
rna interference GO:0016246 137 0.017
regulation of cell proliferation GO:0042127 105 0.017
mitotic nuclear division GO:0007067 89 0.017
spindle localization GO:0051653 51 0.017
embryonic morphogenesis GO:0048598 152 0.017
establishment of spindle orientation GO:0051294 34 0.017
response to wounding GO:0009611 4 0.017
neuron development GO:0048666 199 0.017
positive regulation of hydrolase activity GO:0051345 38 0.016
regulation of phosphate metabolic process GO:0019220 81 0.016
regulation of purine nucleotide catabolic process GO:0033121 35 0.016
axonogenesis GO:0007409 102 0.016
positive regulation of chromosome segregation GO:0051984 1 0.016
regulation of apoptotic signaling pathway GO:2001233 1 0.016
spindle assembly involved in mitosis GO:0090307 6 0.015
regulation of cell death GO:0010941 65 0.015
Human
meiosis i GO:0007127 19 0.015
Yeast
cell motility GO:0048870 313 0.015
positive regulation of mitotic sister chromatid separation GO:1901970 1 0.015
meiotic cell cycle GO:0051321 335 0.015
positive regulation of phosphorylation GO:0042327 27 0.015
cellular protein localization GO:0034613 75 0.015
Human
protein oligomerization GO:0051259 4 0.015
positive regulation of biosynthetic process GO:0009891 109 0.014
Yeast
regeneration GO:0031099 4 0.014
homeostatic process GO:0042592 51 0.014
cell proliferation GO:0008283 116 0.014
Fly
negative regulation of chromosome segregation GO:0051985 4 0.014
Yeast
positive regulation of gtpase activity GO:0043547 28 0.014
spindle assembly GO:0051225 8 0.014
phagocytosis GO:0006909 115 0.014
cell cell signaling GO:0007267 118 0.014
dna packaging GO:0006323 7 0.014
positive regulation of gtp catabolic process GO:0033126 28 0.013
tissue morphogenesis GO:0048729 65 0.013
digestive tract morphogenesis GO:0048546 76 0.013
response to bacterium GO:0009617 86 0.013
anatomical structure formation involved in morphogenesis GO:0048646 250 0.013
Fly
regulation of protein kinase activity GO:0045859 28 0.013
cell surface receptor signaling pathway GO:0007166 149 0.013
negative regulation of cellular metabolic process GO:0031324 95 0.013
Yeast
ribonucleoside monophosphate metabolic process GO:0009161 45 0.013
establishment of rna localization GO:0051236 3 0.013
regulation of nucleoside metabolic process GO:0009118 37 0.013
regulation of protein catabolic process GO:0042176 13 0.013
amine metabolic process GO:0009308 15 0.012
signal transduction by phosphorylation GO:0023014 31 0.012
regulation of nucleotide catabolic process GO:0030811 35 0.012
regulation of signaling GO:0023051 172 0.012
actomyosin structure organization GO:0031032 154 0.012
intracellular signal transduction GO:0035556 96 0.012
cell projection morphogenesis GO:0048858 148 0.012
actin filament based process GO:0030029 191 0.012
oocyte construction GO:0007308 2 0.012
regulation of signal transduction GO:0009966 135 0.012
maintenance of protein location GO:0045185 15 0.012
positive regulation of nucleotide catabolic process GO:0030813 28 0.012
regulation of protein import into nucleus GO:0042306 3 0.012
regulation of protein targeting GO:1903533 3 0.011
intracellular transport GO:0046907 77 0.011
regulation of hydrolase activity GO:0051336 45 0.011
protein transport GO:0015031 45 0.011
immune response GO:0006955 192 0.011
neuron projection morphogenesis GO:0048812 114 0.011
negative regulation of response to dna damage stimulus GO:2001021 2 0.011
Yeast
engulfment of apoptotic cell GO:0043652 94 0.011
regulation of purine nucleotide metabolic process GO:1900542 37 0.011
rna processing GO:0006396 34 0.011
Yeast
dna replication GO:0006260 15 0.010
Yeast
taxis GO:0042330 128 0.010
negative regulation of rna biosynthetic process GO:1902679 53 0.010
Yeast
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.010
Yeast
chromatin assembly or disassembly GO:0006333 1 0.010
hatching GO:0035188 48 0.010
negative regulation of mitotic cell cycle GO:0045930 42 0.010
Yeast Mouse Worm Fly
pole plasm assembly GO:0007315 2 0.010
establishment of protein localization GO:0045184 50 0.010

cdk-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.015
disease of anatomical entity DOID:7 0 0.013
cancer DOID:162 0 0.012
organ system cancer DOID:0050686 0 0.012
head and neck squamous cell carcinoma DOID:5520 0 0.011
head and neck carcinoma DOID:1542 0 0.011
head and neck cancer DOID:11934 0 0.011
prostate cancer DOID:10283 0 0.010
male reproductive organ cancer DOID:3856 0 0.010
reproductive organ cancer DOID:193 0 0.010
organ system benign neoplasm DOID:0060085 0 0.010
hair follicle neoplasm DOID:5375 0 0.010
benign neoplasm DOID:0060072 0 0.010
skin benign neoplasm DOID:3165 0 0.010
integumentary system benign neoplasm DOID:0060121 0 0.010
gastrointestinal system cancer DOID:3119 0 0.010
disease of mental health DOID:150 0 0.010
developmental disorder of mental health DOID:0060037 0 0.010
specific developmental disorder DOID:0060038 0 0.010
intellectual disability DOID:1059 0 0.010