Caenorhabditis elegans

20 known processes

hlh-4 (CELE_T05G5.2)

Protein HLH-4

hlh-4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development ending in birth or egg hatching GO:0009792 2992 0.196
transport GO:0006810 1093 0.161
locomotion GO:0040011 1634 0.160
post embryonic development GO:0009791 2152 0.155
embryo development GO:0009790 3052 0.144
organ development GO:0048513 1102 0.138
establishment of localization GO:0051234 1171 0.123
multi organism reproductive process GO:0044703 867 0.118
multicellular organism reproduction GO:0032504 819 0.101
reproductive system development GO:0061458 850 0.092
behavior GO:0007610 527 0.091
developmental process involved in reproduction GO:0003006 1165 0.091
multicellular organismal reproductive process GO:0048609 815 0.087
single organism reproductive process GO:0044702 1196 0.086
multi multicellular organism process GO:0044706 390 0.085
gonad development GO:0008406 840 0.082
receptor mediated endocytosis GO:0006898 715 0.077
multi organism reproductive behavior GO:0044705 387 0.075
development of primary sexual characteristics GO:0045137 840 0.075
multicellular organismal aging GO:0010259 812 0.074
regulation of biological quality GO:0065008 741 0.072
oviposition GO:0018991 364 0.072
multicellular organismal reproductive behavior GO:0033057 384 0.072
sex differentiation GO:0007548 909 0.071
localization of cell GO:0051674 313 0.070
vesicle mediated transport GO:0016192 852 0.070
body morphogenesis GO:0010171 620 0.069
reproductive behavior GO:0019098 387 0.068
determination of adult lifespan GO:0008340 812 0.068
aging GO:0007568 812 0.067
maintenance of location GO:0051235 580 0.066
macromolecule localization GO:0033036 771 0.066
regulation of developmental process GO:0050793 684 0.066
negative regulation of biological process GO:0048519 567 0.065
cell development GO:0048468 696 0.065
reproductive structure development GO:0048608 850 0.064
lipid storage GO:0019915 565 0.063
regulation of multicellular organismal process GO:0051239 726 0.063
signaling GO:0023052 401 0.062
multi organism behavior GO:0051705 389 0.061
lipid localization GO:0010876 573 0.059
single organism signaling GO:0044700 401 0.057
endocytosis GO:0006897 819 0.054
cellular component movement GO:0006928 388 0.054
single organism transport GO:0044765 447 0.053
head development GO:0060322 1 0.051
nucleobase containing compound metabolic process GO:0006139 406 0.051
cellular component morphogenesis GO:0032989 318 0.050
cell migration GO:0016477 306 0.050
growth GO:0040007 562 0.049
genitalia development GO:0048806 741 0.049
organelle organization GO:0006996 783 0.049
post embryonic organ development GO:0048569 336 0.048
positive regulation of developmental process GO:0051094 408 0.048
response to chemical GO:0042221 356 0.045
regulation of macromolecule metabolic process GO:0060255 421 0.045
axon development GO:0061564 163 0.045
single organism localization GO:1902578 518 0.044
regulation of metabolic process GO:0019222 478 0.043
developmental growth GO:0048589 412 0.043
positive regulation of multicellular organismal process GO:0051240 417 0.043
cell motility GO:0048870 313 0.043
anatomical structure formation involved in morphogenesis GO:0048646 250 0.042
regulation of multicellular organismal development GO:2000026 317 0.042
positive regulation of cellular process GO:0048522 332 0.041
protein metabolic process GO:0019538 422 0.041
positive regulation of growth GO:0045927 369 0.040
signal transduction GO:0007165 317 0.040
gene expression GO:0010467 412 0.040
cell cycle process GO:0022402 482 0.040
cell projection organization GO:0030030 231 0.040
neuron differentiation GO:0030182 217 0.040
regulation of gene expression GO:0010468 366 0.039
generation of neurons GO:0048699 235 0.039
negative regulation of multicellular organismal process GO:0051241 236 0.039
vulval development GO:0040025 333 0.039
cell fate commitment GO:0045165 139 0.038
response to external stimulus GO:0009605 289 0.038
regulation of growth GO:0040008 409 0.038
neuron development GO:0048666 199 0.037
hermaphrodite genitalia development GO:0040035 734 0.037
multicellular organism growth GO:0035264 385 0.037
regulation of multicellular organism growth GO:0040014 373 0.037
regulation of developmental growth GO:0048638 389 0.036
regulation of cell cycle GO:0051726 194 0.036
cell division GO:0051301 262 0.036
neuron projection development GO:0031175 187 0.036
single organism organelle organization GO:1902589 501 0.035
molting cycle GO:0042303 281 0.035
establishment of localization in cell GO:0051649 318 0.034
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.034
cellular localization GO:0051641 360 0.033
cell death GO:0008219 547 0.033
death GO:0016265 547 0.033
positive regulation of developmental growth GO:0048639 354 0.033
regulation of nematode larval development GO:0061062 260 0.033
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.032
cell part morphogenesis GO:0032990 152 0.032
regulation of vulval development GO:0040028 248 0.032
programmed cell death GO:0012501 500 0.032
regulation of cellular metabolic process GO:0031323 305 0.032
cell cycle GO:0007049 526 0.031
cellular nitrogen compound biosynthetic process GO:0044271 192 0.031
negative regulation of post embryonic development GO:0048581 208 0.031
positive regulation of multicellular organism growth GO:0040018 352 0.030
biosynthetic process GO:0009058 323 0.030
regulation of locomotion GO:0040012 161 0.030
regulation of signaling GO:0023051 172 0.030
organelle fission GO:0048285 363 0.030
regulation of post embryonic development GO:0048580 260 0.029
nervous system development GO:0007399 253 0.029
response to wounding GO:0009611 4 0.029
neurogenesis GO:0022008 236 0.029
gamete generation GO:0007276 461 0.029
dauer larval development GO:0040024 92 0.029
axonogenesis GO:0007409 102 0.028
cytoskeleton organization GO:0007010 339 0.028
macromolecule biosynthetic process GO:0009059 250 0.028
axon guidance GO:0007411 82 0.028
sensory organ morphogenesis GO:0090596 2 0.028
male sex differentiation GO:0046661 86 0.027
organic substance catabolic process GO:1901575 294 0.027
regulation of localization GO:0032879 194 0.027
regulation of nitrogen compound metabolic process GO:0051171 222 0.027
sexual reproduction GO:0019953 546 0.027
rna biosynthetic process GO:0032774 169 0.027
negative regulation of developmental process GO:0051093 227 0.027
apoptotic process GO:0006915 478 0.026
catabolic process GO:0009056 318 0.026
regulation of cellular component organization GO:0051128 248 0.026
regulation of cell communication GO:0010646 176 0.025
inductive cell migration GO:0040039 145 0.025
cellular biosynthetic process GO:0044249 315 0.025
male anatomical structure morphogenesis GO:0090598 78 0.025
skeletal muscle organ development GO:0060538 3 0.025
cell morphogenesis involved in differentiation GO:0000904 112 0.025
regulation of nuclear division GO:0051783 115 0.025
macromolecular complex subunit organization GO:0043933 320 0.024
cell surface receptor signaling pathway GO:0007166 149 0.024
neuron projection extension GO:1990138 37 0.024
negative regulation of nematode larval development GO:0061064 208 0.024
tissue development GO:0009888 112 0.024
taxis GO:0042330 128 0.024
cell projection morphogenesis GO:0048858 148 0.024
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.024
regulation of cell migration GO:0030334 55 0.024
regulation of meiotic cell cycle GO:0051445 136 0.024
negative regulation of metabolic process GO:0009892 240 0.024
intracellular signal transduction GO:0035556 96 0.024
regulation of cell division GO:0051302 142 0.023
cell morphogenesis GO:0000902 163 0.023
meiotic nuclear division GO:0007126 300 0.023
negative regulation of macromolecule metabolic process GO:0010605 229 0.023
rna metabolic process GO:0016070 228 0.023
cellular component biogenesis GO:0044085 297 0.023
organic substance biosynthetic process GO:1901576 323 0.023
regulation of response to stimulus GO:0048583 243 0.023
regulation of rna metabolic process GO:0051252 173 0.023
regulation of primary metabolic process GO:0080090 292 0.023
protein localization GO:0008104 205 0.023
cellular component assembly GO:0022607 293 0.023
positive regulation of cellular metabolic process GO:0031325 178 0.023
digestive tract development GO:0048565 122 0.022
neuron projection guidance GO:0097485 82 0.022
negative regulation of gene expression GO:0010629 217 0.022
negative regulation of neurogenesis GO:0050768 4 0.022
cellular macromolecule biosynthetic process GO:0034645 247 0.022
neuron projection morphogenesis GO:0048812 114 0.021
system process GO:0003008 136 0.021
response to organic substance GO:0010033 131 0.021
nucleic acid metabolic process GO:0090304 299 0.021
epithelial tube morphogenesis GO:0060562 1 0.021
cell type specific apoptotic process GO:0097285 4 0.021
positive regulation of rna metabolic process GO:0051254 103 0.021
negative regulation of vulval development GO:0040027 206 0.021
transcription from rna polymerase ii promoter GO:0006366 149 0.021
protein complex biogenesis GO:0070271 186 0.020
muscle structure development GO:0061061 191 0.020
chemotaxis GO:0006935 120 0.020
phosphorus metabolic process GO:0006793 232 0.020
organelle assembly GO:0070925 214 0.020
nucleobase containing compound biosynthetic process GO:0034654 184 0.020
aromatic compound biosynthetic process GO:0019438 192 0.020
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.020
regulation of molecular function GO:0065009 89 0.020
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.020
embryonic morphogenesis GO:0048598 152 0.020
regulation of behavior GO:0050795 97 0.020
meiotic cell cycle GO:0051321 335 0.020
actin cytoskeleton organization GO:0030036 184 0.019
phosphate containing compound metabolic process GO:0006796 232 0.019
nematode male tail tip morphogenesis GO:0045138 77 0.019
regulation of cell cycle process GO:0010564 145 0.019
macromolecule catabolic process GO:0009057 202 0.019
protein complex assembly GO:0006461 186 0.019
regulation of transcription dna templated GO:0006355 164 0.019
regulation of organelle organization GO:0033043 164 0.019
regulation of cellular component movement GO:0051270 62 0.019
protein complex subunit organization GO:0071822 280 0.019
regulation of cation channel activity GO:2001257 3 0.019
ion transport GO:0006811 113 0.019
transmembrane transport GO:0055085 110 0.019
macromolecular complex assembly GO:0065003 193 0.018
defense response GO:0006952 296 0.018
positive regulation of neuron differentiation GO:0045666 4 0.018
organonitrogen compound metabolic process GO:1901564 151 0.018
digestive system development GO:0055123 122 0.018
heterocycle biosynthetic process GO:0018130 187 0.018
cellular protein complex assembly GO:0043623 178 0.018
positive regulation of neurogenesis GO:0050769 4 0.018
muscle cell development GO:0055001 158 0.018
female gamete generation GO:0007292 254 0.018
cellular macromolecular complex assembly GO:0034622 184 0.018
protein catabolic process GO:0030163 162 0.018
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.018
positive regulation of nucleic acid templated transcription GO:1903508 102 0.017
posttranscriptional gene silencing by rna GO:0035194 143 0.017
cellular component assembly involved in morphogenesis GO:0010927 183 0.017
myofibril assembly GO:0030239 154 0.017
myosin filament assembly GO:0031034 138 0.017
axon extension GO:0048675 37 0.017
striated muscle cell development GO:0055002 157 0.017
neuron recognition GO:0008038 83 0.017
transcription dna templated GO:0006351 168 0.017
regulation of reproductive process GO:2000241 66 0.017
regulation of gene expression epigenetic GO:0040029 163 0.017
muscle cell differentiation GO:0042692 171 0.017
macromolecule modification GO:0043412 218 0.017
muscle organ morphogenesis GO:0048644 4 0.016
secretion GO:0046903 147 0.016
organic cyclic compound biosynthetic process GO:1901362 195 0.016
actin filament based process GO:0030029 191 0.016
germ cell development GO:0007281 351 0.016
oogenesis GO:0048477 229 0.016
regulation of macromolecule biosynthetic process GO:0010556 189 0.016
posttranscriptional gene silencing GO:0016441 143 0.016
positive regulation of metabolic process GO:0009893 187 0.016
neuromuscular junction development GO:0007528 2 0.016
gene silencing GO:0016458 143 0.016
rna interference GO:0016246 137 0.016
nucleic acid templated transcription GO:0097659 169 0.016
cellular response to chemical stimulus GO:0070887 129 0.016
organic substance transport GO:0071702 113 0.016
striated muscle cell differentiation GO:0051146 158 0.015
regulation of cell proliferation GO:0042127 105 0.015
secretion by cell GO:0032940 138 0.015
axonal fasciculation GO:0007413 79 0.015
negative regulation of cellular process GO:0048523 239 0.015
adult behavior GO:0030534 3 0.015
gene silencing by rna GO:0031047 143 0.015
regulation of cellular biosynthetic process GO:0031326 189 0.015
nonmotile primary cilium assembly GO:0035058 18 0.015
regulation of meiosis GO:0040020 94 0.015
regulation of nucleic acid templated transcription GO:1903506 165 0.015
cellular protein metabolic process GO:0044267 279 0.015
response to abiotic stimulus GO:0009628 152 0.015
regulation of oviposition GO:0046662 43 0.015
striated muscle myosin thick filament assembly GO:0071688 138 0.015
positive regulation of cell migration GO:0030335 3 0.015
positive regulation of rna biosynthetic process GO:1902680 102 0.015
response to acid chemical GO:0001101 4 0.015
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.015
muscle tissue development GO:0060537 1 0.015
regulation of cellular amine metabolic process GO:0033238 0 0.014
tube development GO:0035295 126 0.014
cell proliferation GO:0008283 116 0.014
pattern specification process GO:0007389 59 0.014
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.014
posttranscriptional regulation of gene expression GO:0010608 166 0.014
small molecule metabolic process GO:0044281 186 0.014
regulation of biosynthetic process GO:0009889 189 0.014
myosin filament organization GO:0031033 138 0.014
actomyosin structure organization GO:0031032 154 0.014
cellular catabolic process GO:0044248 199 0.014
single organism behavior GO:0044708 83 0.014
regulation of rna biosynthetic process GO:2001141 165 0.014
regulation of cell motility GO:2000145 57 0.014
cell recognition GO:0008037 85 0.014
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.014
adult locomotory behavior GO:0008344 1 0.013
protein modification process GO:0036211 207 0.013
purine ribonucleotide metabolic process GO:0009150 95 0.013
response to other organism GO:0051707 101 0.013
cell cell signaling GO:0007267 118 0.013
ion transmembrane transport GO:0034220 91 0.013
positive regulation of transcription dna templated GO:0045893 102 0.013
regulation of signal transduction GO:0009966 135 0.013
positive regulation of cellular biosynthetic process GO:0031328 109 0.013
regulation of cell projection assembly GO:0060491 3 0.013
calcium mediated signaling GO:0019722 3 0.013
cellular amine metabolic process GO:0044106 15 0.013
regeneration GO:0031099 4 0.013
positive regulation of gene expression GO:0010628 112 0.013
developmental growth involved in morphogenesis GO:0060560 37 0.013
tissue morphogenesis GO:0048729 65 0.013
detection of external stimulus GO:0009581 4 0.013
regulation of multi organism process GO:0043900 69 0.013
cuticle development GO:0042335 100 0.013
regulation of nucleocytoplasmic transport GO:0046822 3 0.013
microtubule based process GO:0007017 182 0.013
mitotic cell cycle process GO:1903047 194 0.013
regulation of organ morphogenesis GO:2000027 4 0.013
mesodermal cell differentiation GO:0048333 15 0.013
rna localization GO:0006403 3 0.013
amine metabolic process GO:0009308 15 0.013
regulation of cytoplasmic transport GO:1903649 3 0.013
carbohydrate derivative metabolic process GO:1901135 141 0.013
cellular protein modification process GO:0006464 207 0.012
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.012
mesodermal cell fate specification GO:0007501 13 0.012
regulation of cellular ketone metabolic process GO:0010565 3 0.012
regulation of response to wounding GO:1903034 1 0.012
gastrulation GO:0007369 58 0.012
acetate ester metabolic process GO:1900619 4 0.012
positive regulation of macromolecule metabolic process GO:0010604 149 0.012
neurological system process GO:0050877 53 0.012
apoptotic cell clearance GO:0043277 111 0.012
protein oligomerization GO:0051259 4 0.012
regulation of epithelial cell differentiation GO:0030856 4 0.012
phosphorylation GO:0016310 116 0.012
negative regulation of transmembrane transport GO:0034763 3 0.012
negative regulation of neuron differentiation GO:0045665 4 0.012
membrane organization GO:0061024 135 0.012
positive regulation of post embryonic development GO:0048582 54 0.012
rho protein signal transduction GO:0007266 2 0.012
small gtpase mediated signal transduction GO:0007264 32 0.012
cell substrate adhesion GO:0031589 1 0.011
cellular response to organic substance GO:0071310 119 0.011
memory GO:0007613 3 0.011
regulation of lipid metabolic process GO:0019216 4 0.011
digestive tract morphogenesis GO:0048546 76 0.011
cellular response to abiotic stimulus GO:0071214 4 0.011
single organism catabolic process GO:0044712 129 0.011
organophosphate metabolic process GO:0019637 125 0.011
regulation of apoptotic signaling pathway GO:2001233 1 0.011
response to bacterium GO:0009617 86 0.011
lipid metabolic process GO:0006629 77 0.011
collagen and cuticulin based cuticle development GO:0040002 99 0.011
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.011
carboxylic acid metabolic process GO:0019752 34 0.011
regulation of synapse assembly GO:0051963 2 0.011
cellular response to stress GO:0033554 162 0.011
organic acid metabolic process GO:0006082 47 0.011
cellular amino acid metabolic process GO:0006520 15 0.011
negative regulation of ion transmembrane transporter activity GO:0032413 3 0.011
phagocytosis engulfment GO:0006911 98 0.011
negative regulation of transporter activity GO:0032410 3 0.011
ribonucleoside triphosphate metabolic process GO:0009199 87 0.011
synaptic growth at neuromuscular junction GO:0051124 1 0.011
cellular nitrogen compound catabolic process GO:0044270 119 0.011
regulation of cellular amino acid metabolic process GO:0006521 0 0.011
immune response GO:0006955 192 0.011
hormone transport GO:0009914 2 0.011
regulation of anatomical structure size GO:0090066 46 0.010
cell fate commitment involved in formation of primary germ layer GO:0060795 33 0.010
heterocycle catabolic process GO:0046700 119 0.010
g protein coupled receptor signaling pathway GO:0007186 46 0.010
single organism biosynthetic process GO:0044711 91 0.010
membrane invagination GO:0010324 98 0.010
positive regulation of cell cycle GO:0045787 55 0.010
intracellular receptor signaling pathway GO:0030522 2 0.010
ribose phosphate metabolic process GO:0019693 99 0.010
regulation of protein import into nucleus GO:0042306 3 0.010
oxoacid metabolic process GO:0043436 47 0.010
pharynx development GO:0060465 51 0.010
organic cyclic compound catabolic process GO:1901361 119 0.010
ribonucleotide metabolic process GO:0009259 99 0.010
phagocytosis GO:0006909 115 0.010
defense response to bacterium GO:0042742 86 0.010
tube morphogenesis GO:0035239 79 0.010

hlh-4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.019
nervous system disease DOID:863 0 0.011
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011
organ system cancer DOID:0050686 0 0.011