Caenorhabditis elegans

108 known processes

dsh-2 (CELE_C27A2.6)

Protein DSH-2

dsh-2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development GO:0009790 3052 0.949
embryo development ending in birth or egg hatching GO:0009792 2992 0.899
sexual reproduction GO:0019953 546 0.898
Fly
mitotic cell cycle process GO:1903047 194 0.781
gamete generation GO:0007276 461 0.763
Fly
multicellular organism reproduction GO:0032504 819 0.760
Worm Fly
meiotic cell cycle process GO:1903046 170 0.719
single organism reproductive process GO:0044702 1196 0.689
meiotic cell cycle GO:0051321 335 0.657
regulation of primary metabolic process GO:0080090 292 0.650
Human Mouse
protein modification process GO:0036211 207 0.630
Human Mouse
germ cell development GO:0007281 351 0.620
Fly
nucleic acid metabolic process GO:0090304 299 0.549
Human
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.546
Fly
regulation of mitotic cell cycle GO:0007346 76 0.535
positive regulation of cellular process GO:0048522 332 0.531
Human Mouse
hermaphrodite genitalia development GO:0040035 734 0.514
meiotic nuclear division GO:0007126 300 0.513
rna metabolic process GO:0016070 228 0.496
Human
cell cycle GO:0007049 526 0.483
cell cycle process GO:0022402 482 0.477
single organism organelle organization GO:1902589 501 0.476
organ development GO:0048513 1102 0.468
cell development GO:0048468 696 0.466
Mouse Fly
mitotic spindle organization GO:0007052 81 0.464
Worm
locomotion GO:0040011 1634 0.459
mitotic nuclear division GO:0007067 89 0.449
regulation of cell cycle process GO:0010564 145 0.441
post embryonic development GO:0009791 2152 0.440
genitalia development GO:0048806 741 0.432
multicellular organismal reproductive process GO:0048609 815 0.426
Worm Fly
chromosome segregation GO:0007059 180 0.423
spindle organization GO:0007051 92 0.417
Worm
regulation of cellular metabolic process GO:0031323 305 0.402
Human Mouse
cell fate commitment GO:0045165 139 0.395
regulation of metabolic process GO:0019222 478 0.394
Human Mouse Worm
gene expression GO:0010467 412 0.371
Human
cellular protein modification process GO:0006464 207 0.364
Human Mouse
sex differentiation GO:0007548 909 0.350
regulation of microtubule cytoskeleton organization GO:0070507 21 0.349
regulation of vulval development GO:0040028 248 0.342
cellular component morphogenesis GO:0032989 318 0.335
Mouse Fly
developmental process involved in reproduction GO:0003006 1165 0.332
regulation of gene expression GO:0010468 366 0.328
Human Worm
nucleobase containing compound metabolic process GO:0006139 406 0.323
Human
regulation of cellular biosynthetic process GO:0031326 189 0.318
Human
organelle organization GO:0006996 783 0.318
macromolecule biosynthetic process GO:0009059 250 0.317
Human
protein localization GO:0008104 205 0.315
nucleic acid templated transcription GO:0097659 169 0.303
Human
reproductive system development GO:0061458 850 0.297
development of primary sexual characteristics GO:0045137 840 0.288
cell division GO:0051301 262 0.286
organic cyclic compound biosynthetic process GO:1901362 195 0.281
Human
regulation of cell cycle GO:0051726 194 0.275
gastrulation GO:0007369 58 0.274
endocytosis GO:0006897 819 0.271
transport GO:0006810 1093 0.263
Mouse
regulation of nucleic acid templated transcription GO:1903506 165 0.254
Human
negative regulation of developmental process GO:0051093 227 0.252
Fly
multi organism reproductive process GO:0044703 867 0.249
Worm Fly
female gamete generation GO:0007292 254 0.247
Fly
cytoskeleton organization GO:0007010 339 0.247
organelle fission GO:0048285 363 0.239
regulation of developmental process GO:0050793 684 0.234
Human Mouse Worm Fly
reproductive structure development GO:0048608 850 0.234
meiotic chromosome segregation GO:0045132 139 0.234
establishment of localization GO:0051234 1171 0.233
cellular protein metabolic process GO:0044267 279 0.228
Human Mouse
cellular component movement GO:0006928 388 0.227
Zebrafish Mouse Worm Fly
negative regulation of biological process GO:0048519 567 0.223
Human Mouse Fly
oogenesis GO:0048477 229 0.212
Fly
cellular component assembly GO:0022607 293 0.211
Fly
receptor mediated endocytosis GO:0006898 715 0.205
vesicle mediated transport GO:0016192 852 0.200
negative regulation of metabolic process GO:0009892 240 0.199
Human Mouse
cell projection morphogenesis GO:0048858 148 0.195
Mouse Fly
aging GO:0007568 812 0.195
digestive tract development GO:0048565 122 0.194
cellular nitrogen compound biosynthetic process GO:0044271 192 0.193
Human
gonad development GO:0008406 840 0.187
cellular catabolic process GO:0044248 199 0.187
Human
response to chemical GO:0042221 356 0.183
Mouse Fly
vulval development GO:0040025 333 0.182
macromolecule localization GO:0033036 771 0.176
post embryonic organ development GO:0048569 336 0.176
Fly
aromatic compound biosynthetic process GO:0019438 192 0.174
Human
neuron projection morphogenesis GO:0048812 114 0.172
Mouse Fly
regulation of cell communication GO:0010646 176 0.172
Human Mouse Fly
cell part morphogenesis GO:0032990 152 0.171
Mouse Fly
organelle assembly GO:0070925 214 0.170
positive regulation of vulval development GO:0040026 52 0.168
epidermis morphogenesis GO:0048730 7 0.166
Worm Fly
cell migration GO:0016477 306 0.162
Zebrafish Worm Fly
negative regulation of cellular process GO:0048523 239 0.161
Human Mouse Fly
positive regulation of cellular metabolic process GO:0031325 178 0.160
Human Mouse
positive regulation of transcription dna templated GO:0045893 102 0.158
Human
positive regulation of developmental process GO:0051094 408 0.157
Mouse Fly
regulation of cytoskeleton organization GO:0051493 41 0.155
rna biosynthetic process GO:0032774 169 0.154
Human
cellular localization GO:0051641 360 0.150
regulation of nematode larval development GO:0061062 260 0.149
regulation of protein metabolic process GO:0051246 81 0.149
Human Mouse
positive regulation of multicellular organismal process GO:0051240 417 0.146
Mouse Fly
determination of adult lifespan GO:0008340 812 0.146
regulation of biosynthetic process GO:0009889 189 0.144
Human
oocyte differentiation GO:0009994 45 0.141
regulation of macromolecule metabolic process GO:0060255 421 0.137
Human Mouse Worm
macromolecular complex assembly GO:0065003 193 0.136
cell cycle phase transition GO:0044770 19 0.135
microtubule based process GO:0007017 182 0.134
cellular macromolecule localization GO:0070727 75 0.133
Human Mouse
regulation of meiotic cell cycle GO:0051445 136 0.133
regulation of post embryonic development GO:0048580 260 0.132
cell motility GO:0048870 313 0.132
Zebrafish Worm Fly
regulation of multicellular organismal process GO:0051239 726 0.131
Human Mouse Worm Fly
protein complex assembly GO:0006461 186 0.129
generation of neurons GO:0048699 235 0.127
Mouse Worm Fly
cellular macromolecule biosynthetic process GO:0034645 247 0.127
Human
cell projection organization GO:0030030 231 0.126
Mouse Fly
regulation of rna metabolic process GO:0051252 173 0.122
Human
oocyte development GO:0048599 44 0.121
anatomical structure formation involved in morphogenesis GO:0048646 250 0.118
regulation of multicellular organismal development GO:2000026 317 0.117
Human Mouse Worm Fly
protein complex subunit organization GO:0071822 280 0.117
Mouse Worm Fly
positive regulation of cell cycle GO:0045787 55 0.115
regulation of mitotic metaphase anaphase transition GO:0030071 5 0.115
positive regulation of metabolic process GO:0009893 187 0.114
Human Mouse
cellular component biogenesis GO:0044085 297 0.114
Fly
tube morphogenesis GO:0035239 79 0.112
growth GO:0040007 562 0.110
Zebrafish Mouse Fly
death GO:0016265 547 0.110
regulation of cell fate commitment GO:0010453 22 0.109
Fly
neurogenesis GO:0022008 236 0.109
Mouse Worm Fly
positive regulation of rna biosynthetic process GO:1902680 102 0.108
Human
cell morphogenesis involved in differentiation GO:0000904 112 0.108
Mouse Fly
dna metabolic process GO:0006259 74 0.107
embryonic morphogenesis GO:0048598 152 0.107
positive regulation of nucleic acid templated transcription GO:1903508 102 0.107
Human
macromolecule catabolic process GO:0009057 202 0.106
Human
muscle structure development GO:0061061 191 0.105
digestive tract morphogenesis GO:0048546 76 0.104
cell death GO:0008219 547 0.103
organic substance catabolic process GO:1901575 294 0.103
Human
signaling GO:0023052 401 0.102
neuron projection development GO:0031175 187 0.102
Mouse Fly
negative regulation of post embryonic development GO:0048581 208 0.101
female meiotic division GO:0007143 17 0.101
cytokinesis GO:0000910 80 0.100
biosynthetic process GO:0009058 323 0.099
Human
multicellular organismal aging GO:0010259 812 0.098
programmed cell death GO:0012501 500 0.098
mitotic sister chromatid segregation GO:0000070 38 0.098
neuron development GO:0048666 199 0.096
Mouse Fly
regulation of biological quality GO:0065008 741 0.095
Mouse Fly
regulation of cytokinesis GO:0032465 10 0.093
cellular biosynthetic process GO:0044249 315 0.093
Human
regulation of cell division GO:0051302 142 0.092
negative regulation of multicellular organismal process GO:0051241 236 0.091
Fly
catabolic process GO:0009056 318 0.091
Human
regulation of signaling GO:0023051 172 0.090
Human Mouse Fly
phosphorylation GO:0016310 116 0.089
Human Mouse
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.088
Human
regulation of cellular component organization GO:0051128 248 0.087
nervous system development GO:0007399 253 0.087
Human Zebrafish Mouse Worm Fly
regulation of rna biosynthetic process GO:2001141 165 0.086
Human
nucleobase containing compound biosynthetic process GO:0034654 184 0.086
Human
single organism localization GO:1902578 518 0.086
protein metabolic process GO:0019538 422 0.085
Human Mouse
apoptotic process GO:0006915 478 0.083
cellular macromolecular complex assembly GO:0034622 184 0.082
localization of cell GO:0051674 313 0.082
Zebrafish Worm Fly
positive regulation of nematode larval development GO:0061063 54 0.082
negative regulation of cell cycle GO:0045786 53 0.080
maintenance of location GO:0051235 580 0.080
macromolecular complex subunit organization GO:0043933 320 0.079
Mouse Worm Fly
negative regulation of macromolecule metabolic process GO:0010605 229 0.079
Human Mouse
negative regulation of vulval development GO:0040027 206 0.078
negative regulation of mitotic cell cycle GO:0045930 42 0.078
protein phosphorylation GO:0006468 85 0.078
Human Mouse
cell morphogenesis GO:0000902 163 0.078
Mouse Fly
neuron projection guidance GO:0097485 82 0.077
Mouse Fly
gene silencing GO:0016458 143 0.076
regulation of developmental growth GO:0048638 389 0.075
positive regulation of chromosome organization GO:2001252 2 0.075
nucleobase containing compound catabolic process GO:0034655 114 0.074
tube formation GO:0035148 2 0.073
Mouse
posttranscriptional regulation of gene expression GO:0010608 166 0.073
chromosome organization involved in meiosis GO:0070192 25 0.072
anterior posterior pattern specification GO:0009952 27 0.072
negative regulation of nematode larval development GO:0061064 208 0.072
neuron differentiation GO:0030182 217 0.072
Mouse Fly
macromolecule modification GO:0043412 218 0.071
Human Mouse
histone modification GO:0016570 30 0.070
protein localization to organelle GO:0033365 37 0.070
Human Mouse
chromosome organization GO:0051276 104 0.069
protein complex biogenesis GO:0070271 186 0.069
fertilization GO:0009566 63 0.068
cellular protein catabolic process GO:0044257 37 0.067
Human
regulation of multicellular organism growth GO:0040014 373 0.067
organelle localization GO:0051640 127 0.067
molting cycle GO:0042303 281 0.067
regulation of cell differentiation GO:0045595 81 0.066
Mouse Fly
cellular nitrogen compound catabolic process GO:0044270 119 0.064
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.064
Human
digestive system development GO:0055123 122 0.063
regulation of organelle organization GO:0033043 164 0.062
cellular protein complex assembly GO:0043623 178 0.062
negative regulation of gene expression GO:0010629 217 0.062
positive regulation of gene expression GO:0010628 112 0.062
Human
cell proliferation GO:0008283 116 0.062
regulation of nucleocytoplasmic transport GO:0046822 3 0.061
lipid storage GO:0019915 565 0.060
actin filament based process GO:0030029 191 0.060
Fly
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.060
Mouse Fly
canonical wnt signaling pathway GO:0060070 3 0.060
Human Mouse Fly
attachment of spindle microtubules to kinetochore GO:0008608 8 0.060
inductive cell migration GO:0040039 145 0.059
Worm
regulation of cellular protein metabolic process GO:0032268 75 0.059
Human Mouse
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.059
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.058
regulation of response to stimulus GO:0048583 243 0.058
Human Mouse Fly
positive regulation of biosynthetic process GO:0009891 109 0.057
Human
muscle tissue development GO:0060537 1 0.057
positive regulation of chromosome segregation GO:0051984 1 0.056
regulation of cell development GO:0060284 49 0.056
Mouse
positive regulation of growth GO:0045927 369 0.055
system process GO:0003008 136 0.055
Mouse
multi organism reproductive behavior GO:0044705 387 0.055
Worm
lipid localization GO:0010876 573 0.053
cellular protein localization GO:0034613 75 0.051
Human Mouse
head development GO:0060322 1 0.051
Zebrafish
phosphorus metabolic process GO:0006793 232 0.051
Human Mouse
body morphogenesis GO:0010171 620 0.051
multicellular organism growth GO:0035264 385 0.050
microtubule cytoskeleton organization involved in mitosis GO:1902850 12 0.049
ras protein signal transduction GO:0007265 31 0.049
nucleus organization GO:0006997 38 0.049
signal transduction GO:0007165 317 0.048
negative regulation of cellular protein metabolic process GO:0032269 27 0.047
Human Mouse
organ morphogenesis GO:0009887 67 0.047
rna interference GO:0016246 137 0.046
reproductive behavior GO:0019098 387 0.046
Worm
cellular response to chemical stimulus GO:0070887 129 0.046
protein modification by small protein conjugation or removal GO:0070647 40 0.045
regulation of cell fate specification GO:0042659 22 0.045
Fly
axon development GO:0061564 163 0.045
Mouse Fly
positive regulation of multicellular organism growth GO:0040018 352 0.045
chromatin organization GO:0006325 32 0.045
regulation of growth GO:0040008 409 0.044
proteolysis involved in cellular protein catabolic process GO:0051603 32 0.044
Human
regulation of protein import into nucleus GO:0042306 3 0.043
asymmetric cell division GO:0008356 36 0.043
dna recombination GO:0006310 19 0.043
ribonucleoside monophosphate metabolic process GO:0009161 45 0.042
oviposition GO:0018991 364 0.042
Worm
ribonucleoprotein complex assembly GO:0022618 4 0.042
polar body extrusion after meiotic divisions GO:0040038 14 0.042
establishment of organelle localization GO:0051656 123 0.041
maintenance of protein location GO:0045185 15 0.041
regulation of microtubule based process GO:0032886 21 0.041
posttranscriptional gene silencing GO:0016441 143 0.040
positive regulation of protein metabolic process GO:0051247 45 0.040
Human Mouse
maintenance of protein location in cell GO:0032507 12 0.040
positive regulation of catabolic process GO:0009896 38 0.039
Human
negative regulation of mitotic metaphase anaphase transition GO:0045841 4 0.039
small gtpase mediated signal transduction GO:0007264 32 0.039
chromatin modification GO:0016568 32 0.039
regulation of nitrogen compound metabolic process GO:0051171 222 0.038
Human
developmental growth GO:0048589 412 0.038
Zebrafish Mouse Fly
regulation of phosphorus metabolic process GO:0051174 81 0.038
Human Mouse
actomyosin structure organization GO:0031032 154 0.038
regulation of signal transduction GO:0009966 135 0.038
Human Mouse Fly
regulation of cytoplasmic transport GO:1903649 3 0.037
membrane organization GO:0061024 135 0.037
Mouse
establishment of localization in cell GO:0051649 318 0.037
positive regulation of rna metabolic process GO:0051254 103 0.037
Human
cellular response to organic substance GO:0071310 119 0.037
embryonic pattern specification GO:0009880 21 0.037
regulation of nuclear division GO:0051783 115 0.036
meiosis i GO:0007127 19 0.036
transcription dna templated GO:0006351 168 0.036
Human
posttranscriptional gene silencing by rna GO:0035194 143 0.035
multicellular organismal reproductive behavior GO:0033057 384 0.035
Worm
single organism catabolic process GO:0044712 129 0.035
cuticle development GO:0042335 100 0.035
nucleus localization GO:0051647 55 0.035
regulation of macromolecule biosynthetic process GO:0010556 189 0.034
Human
dna conformation change GO:0071103 11 0.034
spindle checkpoint GO:0031577 4 0.034
regulation of programmed cell death GO:0043067 50 0.034
positive regulation of mitotic sister chromatid separation GO:1901970 1 0.033
proteasomal protein catabolic process GO:0010498 20 0.033
Human
spindle assembly involved in mitosis GO:0090307 6 0.033
nucleoside phosphate catabolic process GO:1901292 77 0.033
single organism transport GO:0044765 447 0.033
Mouse
organophosphate metabolic process GO:0019637 125 0.032
tube development GO:0035295 126 0.032
multi organism behavior GO:0051705 389 0.032
Mouse Worm
regulation of cell cycle phase transition GO:1901987 13 0.032
small molecule metabolic process GO:0044281 186 0.032
dna packaging GO:0006323 7 0.032
nucleotide metabolic process GO:0009117 108 0.031
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 20 0.031
Human
mitotic sister chromatid separation GO:0051306 13 0.031
phagocytosis GO:0006909 115 0.030
negative regulation of cell cycle process GO:0010948 12 0.030
sister chromatid segregation GO:0000819 46 0.030
regulation of cell proliferation GO:0042127 105 0.030
Human
modification dependent macromolecule catabolic process GO:0043632 32 0.030
Human
muscle organ development GO:0007517 26 0.030
heterocycle biosynthetic process GO:0018130 187 0.030
Human
positive regulation of cytokinesis GO:0032467 3 0.029
negative regulation of mitotic cell cycle phase transition GO:1901991 5 0.029
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.029
regulation of cellular localization GO:0060341 42 0.029
multi multicellular organism process GO:0044706 390 0.029
Worm
microtubule anchoring GO:0034453 8 0.028
positive regulation of developmental growth GO:0048639 354 0.028
chromatin remodeling GO:0006338 2 0.028
taxis GO:0042330 128 0.028
Mouse Fly
ribose phosphate metabolic process GO:0019693 99 0.028
striated muscle cell differentiation GO:0051146 158 0.027
cellular component assembly involved in morphogenesis GO:0010927 183 0.027
positive regulation of macromolecule metabolic process GO:0010604 149 0.027
Human Mouse
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.027
Human
cellular response to stress GO:0033554 162 0.027
Human Mouse
regionalization GO:0003002 31 0.027
Mouse Fly
pattern specification process GO:0007389 59 0.027
Mouse Worm Fly
metaphase anaphase transition of cell cycle GO:0044784 15 0.026
regulation of mitotic spindle organization GO:0060236 3 0.026
mitotic cell cycle phase transition GO:0044772 13 0.026
skeletal muscle organ development GO:0060538 3 0.026
regulation of localization GO:0032879 194 0.026
heterocycle catabolic process GO:0046700 119 0.026
proximal distal pattern formation GO:0009954 6 0.026
regulation of gene expression epigenetic GO:0040029 163 0.025
regulation of actin filament based process GO:0032970 22 0.025
Fly
purine ribonucleotide catabolic process GO:0009154 75 0.025
regulation of organ morphogenesis GO:2000027 4 0.025
Human Mouse Worm Fly
cell projection assembly GO:0030031 35 0.025
Fly
striated muscle myosin thick filament assembly GO:0071688 138 0.024
cellular macromolecule catabolic process GO:0044265 73 0.024
Human
dna templated transcription elongation GO:0006354 1 0.024
chromatin assembly or disassembly GO:0006333 1 0.024
positive regulation of post embryonic development GO:0048582 54 0.024
establishment of vesicle localization GO:0051650 23 0.024
aromatic compound catabolic process GO:0019439 116 0.024
regulation of meiosis GO:0040020 94 0.024
organic substance transport GO:0071702 113 0.023
positive regulation of neurogenesis GO:0050769 4 0.023
Mouse
regulation of protein localization to nucleus GO:1900180 5 0.023
response to organic cyclic compound GO:0014070 10 0.023
striated muscle cell development GO:0055002 157 0.023
asymmetric protein localization GO:0008105 35 0.023
behavior GO:0007610 527 0.023
Mouse Worm
male sex differentiation GO:0046661 86 0.023
negative regulation of gene expression epigenetic GO:0045814 2 0.023
tissue morphogenesis GO:0048729 65 0.022
Human Zebrafish Mouse Worm Fly
positive regulation of cell death GO:0010942 38 0.022
stem cell division GO:0017145 18 0.022
regulation of protein targeting GO:1903533 3 0.022
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.022
Human
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.022
Human
regulation of catabolic process GO:0009894 57 0.022
Human
metaphase plate congression GO:0051310 5 0.022
spindle assembly GO:0051225 8 0.022
transcription from rna polymerase ii promoter GO:0006366 149 0.022
Human
axon guidance GO:0007411 82 0.021
Mouse Fly
mitotic metaphase plate congression GO:0007080 5 0.021
modification dependent protein catabolic process GO:0019941 32 0.021
Human
regulation of neurogenesis GO:0050767 40 0.021
Mouse
nucleoside triphosphate metabolic process GO:0009141 87 0.021
single organism intracellular transport GO:1902582 70 0.021
rna localization GO:0006403 3 0.021
cell surface receptor signaling pathway GO:0007166 149 0.020
single fertilization GO:0007338 61 0.020
response to organic substance GO:0010033 131 0.020
epithelial tube morphogenesis GO:0060562 1 0.020
Mouse
developmental induction GO:0031128 1 0.020
Fly
response to wounding GO:0009611 4 0.020
meiotic cytokinesis GO:0033206 15 0.020
cytoskeleton dependent cytokinesis GO:0061640 35 0.020
long term memory GO:0007616 2 0.020
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.020
Human
establishment or maintenance of cell polarity GO:0007163 63 0.020
positive regulation of embryonic development GO:0040019 3 0.020
positive regulation of cellular biosynthetic process GO:0031328 109 0.020
Human
establishment of spindle localization GO:0051293 51 0.019
metaphase anaphase transition of mitotic cell cycle GO:0007091 10 0.019
collagen and cuticulin based cuticle development GO:0040002 99 0.019
apical junction assembly GO:0043297 1 0.019
epithelial cell proliferation GO:0050673 1 0.019
stem cell differentiation GO:0048863 7 0.019
Fly
chromosome localization GO:0050000 10 0.019
organonitrogen compound metabolic process GO:1901564 151 0.019
male gamete generation GO:0048232 41 0.019
regulation of protein catabolic process GO:0042176 13 0.019
Human
response to external stimulus GO:0009605 289 0.018
Mouse Fly
cell cell signaling GO:0007267 118 0.018
Mouse Fly
developmental maturation GO:0021700 26 0.018
response to extracellular stimulus GO:0009991 38 0.018
regulation of sister chromatid segregation GO:0033045 16 0.018
regulation of kinase activity GO:0043549 29 0.018
Human Mouse
regulation of apoptotic signaling pathway GO:2001233 1 0.018
pronuclear migration GO:0035046 51 0.018
regulation of mitotic sister chromatid segregation GO:0033047 16 0.018
response to nutrient levels GO:0031667 35 0.017
negative regulation of neurogenesis GO:0050768 4 0.017
muscle cell development GO:0055001 158 0.017
covalent chromatin modification GO:0016569 30 0.017
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 1 0.017
Human
positive regulation of cellular protein catabolic process GO:1903364 3 0.017
Human
purine ribonucleoside metabolic process GO:0046128 92 0.017
ribonucleoside triphosphate metabolic process GO:0009199 87 0.017
positive regulation of intracellular transport GO:0032388 2 0.017
gene silencing by rna GO:0031047 143 0.017
maintenance of location in cell GO:0051651 12 0.017
g1 s transition of mitotic cell cycle GO:0000082 2 0.017
mitotic chromosome condensation GO:0007076 3 0.017
negative regulation of cellular metabolic process GO:0031324 95 0.017
Human Mouse
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.016
myosin filament organization GO:0031033 138 0.016
regulation of cell death GO:0010941 65 0.016
nucleobase containing small molecule metabolic process GO:0055086 115 0.016
establishment of nucleus localization GO:0040023 55 0.016
regulation of epithelial cell proliferation GO:0050678 1 0.016
regulation of phosphorylation GO:0042325 45 0.016
Human Mouse
purine nucleotide catabolic process GO:0006195 75 0.016
single organism cellular localization GO:1902580 72 0.016
cellular response to nutrient levels GO:0031669 13 0.016
nucleoside metabolic process GO:0009116 99 0.015
myofibril assembly GO:0030239 154 0.015
chromosome separation GO:0051304 19 0.015
single organism signaling GO:0044700 401 0.015
protein localization to nucleus GO:0034504 11 0.015
Human
intracellular transport GO:0046907 77 0.015
positive regulation of catalytic activity GO:0043085 59 0.015
Human Mouse
negative regulation of cell cycle phase transition GO:1901988 6 0.015
positive regulation of cellular catabolic process GO:0031331 35 0.015
Human
organic substance biosynthetic process GO:1901576 323 0.015
Human
regulation of anatomical structure morphogenesis GO:0022603 51 0.015
Human Mouse Worm Fly
centrosome cycle GO:0007098 13 0.015
nuclear migration GO:0007097 54 0.015
protein modification by small protein conjugation GO:0032446 31 0.015
nucleotide catabolic process GO:0009166 77 0.015
regulation of cellular ketone metabolic process GO:0010565 3 0.015
regulation of apoptotic process GO:0042981 36 0.015
endodermal cell differentiation GO:0035987 18 0.015
cell type specific apoptotic process GO:0097285 4 0.014
oxoacid metabolic process GO:0043436 47 0.014
negative regulation of response to external stimulus GO:0032102 3 0.014
Mouse
positive regulation of intracellular protein transport GO:0090316 2 0.014
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.014
negative regulation of protein metabolic process GO:0051248 27 0.014
Human Mouse
cell growth GO:0016049 44 0.014
Mouse Fly
regulation of phosphate metabolic process GO:0019220 81 0.014
Human Mouse
single organism membrane organization GO:0044802 35 0.014
Mouse
negative regulation of biosynthetic process GO:0009890 65 0.014
muscle cell differentiation GO:0042692 171 0.014
mitotic g2 m transition checkpoint GO:0044818 1 0.014
protein oligomerization GO:0051259 4 0.014
base excision repair GO:0006284 4 0.014
regulation of cellular component biogenesis GO:0044087 26 0.014
Fly
positive regulation of phosphorus metabolic process GO:0010562 56 0.014
Human Mouse
purine nucleoside triphosphate metabolic process GO:0009144 87 0.014
regulation of protein localization GO:0032880 50 0.014
centrosome organization GO:0051297 14 0.013
synaptic transmission GO:0007268 106 0.013
Mouse
proteolysis GO:0006508 61 0.013
Human
reciprocal meiotic recombination GO:0007131 11 0.013
positive regulation of signaling GO:0023056 66 0.013
Human Mouse
positive regulation of epithelial cell proliferation GO:0050679 1 0.013
purine containing compound catabolic process GO:0072523 75 0.013
anterior posterior axis specification GO:0009948 17 0.013
atp metabolic process GO:0046034 42 0.013
regulation of mitotic cell cycle embryonic GO:0009794 5 0.013
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 5 0.013
Human
cell maturation GO:0048469 26 0.013
internal peptidyl lysine acetylation GO:0018393 3 0.013
mitotic cell cycle checkpoint GO:0007093 5 0.013
spindle localization GO:0051653 51 0.013
positive regulation of protein transport GO:0051222 4 0.013
phosphate containing compound metabolic process GO:0006796 232 0.012
Human Mouse
regulation of protein modification process GO:0031399 46 0.012
Human Mouse
negative regulation of cell communication GO:0010648 61 0.012
Fly
myosin filament assembly GO:0031034 138 0.012
regeneration GO:0031099 4 0.012
negative regulation of signaling GO:0023057 61 0.012
Fly
microtubule based movement GO:0007018 33 0.012
positive regulation of programmed cell death GO:0043068 27 0.012
internal protein amino acid acetylation GO:0006475 3 0.012

dsh-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.037
disease of cellular proliferation DOID:14566 0 0.037
organ system cancer DOID:0050686 0 0.029
large intestine cancer DOID:5672 0 0.015
gastrointestinal system cancer DOID:3119 0 0.015
intestinal cancer DOID:10155 0 0.015
colorectal cancer DOID:9256 0 0.015