Caenorhabditis elegans

7 known processes

tnt-4 (CELE_T08B1.2)

Protein TNT-4

tnt-4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
post embryonic development GO:0009791 2152 0.262
Worm
protein metabolic process GO:0019538 422 0.177
Worm
vesicle mediated transport GO:0016192 852 0.148
Worm
growth GO:0040007 562 0.143
embryo development ending in birth or egg hatching GO:0009792 2992 0.132
response to topologically incorrect protein GO:0035966 82 0.131
embryo development GO:0009790 3052 0.129
Worm
receptor mediated endocytosis GO:0006898 715 0.110
Worm
organelle assembly GO:0070925 214 0.105
Zebrafish Mouse Worm Fly
organelle organization GO:0006996 783 0.101
Zebrafish Mouse Worm Fly
endocytosis GO:0006897 819 0.099
Worm
body morphogenesis GO:0010171 620 0.096
cytoskeleton organization GO:0007010 339 0.096
Zebrafish Mouse Worm Fly
regulation of biological quality GO:0065008 741 0.089
Worm Fly
multicellular organismal aging GO:0010259 812 0.086
regulation of growth GO:0040008 409 0.082
determination of adult lifespan GO:0008340 812 0.078
protein complex subunit organization GO:0071822 280 0.076
Worm Fly
multicellular organismal reproductive process GO:0048609 815 0.076
Worm
macromolecular complex assembly GO:0065003 193 0.075
Worm
actin filament based process GO:0030029 191 0.073
Human Zebrafish Mouse Worm Fly
generation of neurons GO:0048699 235 0.067
Worm
lipid storage GO:0019915 565 0.066
Worm
cellular component assembly involved in morphogenesis GO:0010927 183 0.063
Zebrafish Mouse Worm Fly
macromolecule localization GO:0033036 771 0.062
Worm
maintenance of location GO:0051235 580 0.061
Worm
reproductive structure development GO:0048608 850 0.060
positive regulation of cellular process GO:0048522 332 0.058
Human
macromolecular complex subunit organization GO:0043933 320 0.058
Worm Fly
myofibril assembly GO:0030239 154 0.057
Zebrafish Mouse Worm Fly
single organism organelle organization GO:1902589 501 0.057
Zebrafish Mouse Worm Fly
apoptotic process GO:0006915 478 0.056
lipid localization GO:0010876 573 0.056
Worm
anatomical structure homeostasis GO:0060249 11 0.055
Fly
regulation of developmental process GO:0050793 684 0.054
hermaphrodite genitalia development GO:0040035 734 0.053
locomotion GO:0040011 1634 0.052
Zebrafish Worm
protein complex biogenesis GO:0070271 186 0.051
Worm
regulation of response to stimulus GO:0048583 243 0.049
Zebrafish Mouse
positive regulation of biosynthetic process GO:0009891 109 0.049
posttranscriptional regulation of gene expression GO:0010608 166 0.048
muscle cell development GO:0055001 158 0.047
Zebrafish Mouse Worm Fly
organ morphogenesis GO:0009887 67 0.046
Human Zebrafish Mouse Fly
cell surface receptor signaling pathway GO:0007166 149 0.044
meiotic nuclear division GO:0007126 300 0.043
gene expression GO:0010467 412 0.042
striated muscle cell development GO:0055002 157 0.041
Zebrafish Mouse Worm Fly
axon development GO:0061564 163 0.041
Worm
transport GO:0006810 1093 0.040
Worm
regulation of multicellular organismal process GO:0051239 726 0.040
Human Zebrafish Mouse Worm
organ development GO:0048513 1102 0.040
Human Zebrafish Mouse Worm Fly
localization of cell GO:0051674 313 0.039
Zebrafish
cellular protein complex assembly GO:0043623 178 0.039
Worm
cellular response to topologically incorrect protein GO:0035967 76 0.038
death GO:0016265 547 0.038
anatomical structure formation involved in morphogenesis GO:0048646 250 0.037
Zebrafish Mouse Worm Fly
positive regulation of growth GO:0045927 369 0.037
establishment of localization GO:0051234 1171 0.037
Worm
multi organism behavior GO:0051705 389 0.036
cell development GO:0048468 696 0.036
Zebrafish Mouse Worm Fly
actin cytoskeleton organization GO:0030036 184 0.035
Zebrafish Mouse Worm Fly
cellular component assembly GO:0022607 293 0.035
Zebrafish Mouse Worm Fly
developmental growth GO:0048589 412 0.034
multi multicellular organism process GO:0044706 390 0.034
cellular macromolecular complex assembly GO:0034622 184 0.034
Worm
regulation of cellular component organization GO:0051128 248 0.034
programmed cell death GO:0012501 500 0.033
regulation of atp catabolic process GO:1903289 3 0.033
Human
cellular component morphogenesis GO:0032989 318 0.033
Zebrafish Mouse Worm Fly
organelle fission GO:0048285 363 0.033
signaling GO:0023052 401 0.033
Zebrafish
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.032
striated muscle cell differentiation GO:0051146 158 0.031
Zebrafish Mouse Worm Fly
negative regulation of cellular process GO:0048523 239 0.031
Human
head development GO:0060322 1 0.031
regulation of apoptotic signaling pathway GO:2001233 1 0.030
regulation of developmental growth GO:0048638 389 0.030
positive regulation of macromolecule metabolic process GO:0010604 149 0.029
cell death GO:0008219 547 0.029
negative regulation of biological process GO:0048519 567 0.029
Human
developmental process involved in reproduction GO:0003006 1165 0.028
single organism reproductive process GO:0044702 1196 0.028
Worm
regulation of metabolic process GO:0019222 478 0.027
Human
cell migration GO:0016477 306 0.027
Zebrafish
aging GO:0007568 812 0.026
positive regulation of developmental process GO:0051094 408 0.026
cellular response to stress GO:0033554 162 0.025
response to endoplasmic reticulum stress GO:0034976 71 0.025
positive regulation of metabolic process GO:0009893 187 0.025
Human
development of primary sexual characteristics GO:0045137 840 0.025
cell motility GO:0048870 313 0.025
Zebrafish
muscle organ morphogenesis GO:0048644 4 0.024
Human Zebrafish Mouse Fly
regulation of multicellular organism growth GO:0040014 373 0.024
phosphate containing compound metabolic process GO:0006796 232 0.024
Human
cellular component biogenesis GO:0044085 297 0.024
Zebrafish Mouse Worm Fly
inductive cell migration GO:0040039 145 0.023
regulation of post embryonic development GO:0048580 260 0.023
sensory organ morphogenesis GO:0090596 2 0.023
regulation of nematode larval development GO:0061062 260 0.023
myosin filament organization GO:0031033 138 0.023
Worm
cell cycle GO:0007049 526 0.023
oviposition GO:0018991 364 0.022
multi organism reproductive process GO:0044703 867 0.022
Worm
sexual reproduction GO:0019953 546 0.021
Worm
nucleobase containing compound metabolic process GO:0006139 406 0.021
Human
negative regulation of gene expression GO:0010629 217 0.021
nervous system development GO:0007399 253 0.021
Worm
response to biotic stimulus GO:0009607 101 0.021
molting cycle GO:0042303 281 0.021
cellular biosynthetic process GO:0044249 315 0.021
Zebrafish
positive regulation of developmental growth GO:0048639 354 0.021
organophosphate catabolic process GO:0046434 81 0.021
Human
rna metabolic process GO:0016070 228 0.020
somatic muscle development GO:0007525 1 0.020
Worm
negative regulation of nematode larval development GO:0061064 208 0.020
multicellular organism reproduction GO:0032504 819 0.020
Worm
protein complex assembly GO:0006461 186 0.020
Worm
regulation of macromolecule metabolic process GO:0060255 421 0.020
positive regulation of cell migration GO:0030335 3 0.020
meiotic cell cycle GO:0051321 335 0.020
positive regulation of multicellular organism growth GO:0040018 352 0.020
cell projection organization GO:0030030 231 0.020
Worm
regulation of vulval development GO:0040028 248 0.019
negative regulation of vulval development GO:0040027 206 0.019
embryonic morphogenesis GO:0048598 152 0.019
Worm
response to wounding GO:0009611 4 0.019
catabolic process GO:0009056 318 0.019
Human Worm
muscle structure development GO:0061061 191 0.019
Human Zebrafish Mouse Worm Fly
phagocytosis engulfment GO:0006911 98 0.019
negative regulation of macromolecule metabolic process GO:0010605 229 0.019
nucleic acid metabolic process GO:0090304 299 0.019
reproductive behavior GO:0019098 387 0.018
regulation of gene expression GO:0010468 366 0.018
regulation of multicellular organismal development GO:2000026 317 0.018
actomyosin structure organization GO:0031032 154 0.018
Zebrafish Mouse Worm Fly
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.018
Human
cell division GO:0051301 262 0.018
muscle tissue development GO:0060537 1 0.017
Human Zebrafish Mouse
protein catabolic process GO:0030163 162 0.017
Worm
cell morphogenesis involved in differentiation GO:0000904 112 0.017
regulation of intracellular signal transduction GO:1902531 77 0.017
Zebrafish
gonad development GO:0008406 840 0.017
muscle cell differentiation GO:0042692 171 0.017
Zebrafish Mouse Worm Fly
regulation of programmed cell death GO:0043067 50 0.017
purine nucleoside monophosphate catabolic process GO:0009128 28 0.017
Human
epithelium development GO:0060429 68 0.016
Zebrafish
sex differentiation GO:0007548 909 0.016
multicellular organismal reproductive behavior GO:0033057 384 0.016
single organism behavior GO:0044708 83 0.016
multicellular organism growth GO:0035264 385 0.016
neurogenesis GO:0022008 236 0.016
Worm
regulation of signaling GO:0023051 172 0.016
Zebrafish
negative regulation of developmental process GO:0051093 227 0.016
cellular component movement GO:0006928 388 0.015
Human Zebrafish
positive regulation of multicellular organismal process GO:0051240 417 0.015
regulation of organelle organization GO:0033043 164 0.015
multi organism reproductive behavior GO:0044705 387 0.015
negative regulation of post embryonic development GO:0048581 208 0.015
regulation of cell migration GO:0030334 55 0.015
membrane invagination GO:0010324 98 0.015
behavior GO:0007610 527 0.014
regulation of rna metabolic process GO:0051252 173 0.014
axonal fasciculation GO:0007413 79 0.014
Worm
striated muscle myosin thick filament assembly GO:0071688 138 0.014
Worm
cell morphogenesis GO:0000902 163 0.014
skeletal muscle organ development GO:0060538 3 0.014
cell recognition GO:0008037 85 0.014
Worm
regulation of cellular metabolic process GO:0031323 305 0.014
Human
er nucleus signaling pathway GO:0006984 66 0.014
negative regulation of multicellular organismal process GO:0051241 236 0.014
Human
single organism signaling GO:0044700 401 0.013
Zebrafish
defense response to other organism GO:0098542 100 0.013
tissue development GO:0009888 112 0.013
Human Zebrafish Mouse Fly
macromolecule catabolic process GO:0009057 202 0.013
Worm
cellular protein metabolic process GO:0044267 279 0.013
single organism localization GO:1902578 518 0.013
macromolecule biosynthetic process GO:0009059 250 0.013
regulation of atpase activity GO:0043462 3 0.013
Human
positive regulation of cysteine type endopeptidase activity GO:2001056 3 0.013
regulation of purine nucleotide catabolic process GO:0033121 35 0.012
Human
regulation of signal transduction GO:0009966 135 0.012
Zebrafish
organic substance catabolic process GO:1901575 294 0.012
Human Worm
endoplasmic reticulum unfolded protein response GO:0030968 66 0.012
negative regulation of metabolic process GO:0009892 240 0.012
Human
regulation of cellular component movement GO:0051270 62 0.012
gamete generation GO:0007276 461 0.012
Worm
response to external biotic stimulus GO:0043207 101 0.012
ribonucleoside triphosphate catabolic process GO:0009203 72 0.012
Human
cell cycle process GO:0022402 482 0.012
actin filament bundle assembly GO:0051017 3 0.012
cell substrate adhesion GO:0031589 1 0.012
genitalia development GO:0048806 741 0.011
cellular macromolecule biosynthetic process GO:0034645 247 0.011
myosin filament assembly GO:0031034 138 0.011
Worm
response to other organism GO:0051707 101 0.011
signal transduction GO:0007165 317 0.011
Zebrafish
regulation of cell motility GO:2000145 57 0.011
positive regulation of cellular metabolic process GO:0031325 178 0.011
Human
negative regulation of signaling GO:0023057 61 0.011
positive regulation of phosphorus metabolic process GO:0010562 56 0.011
Human
response to external stimulus GO:0009605 289 0.010
response to unfolded protein GO:0006986 71 0.010
adult locomotory behavior GO:0008344 1 0.010
actin filament organization GO:0007015 21 0.010
Fly
reproductive system development GO:0061458 850 0.010
regulation of nucleotide catabolic process GO:0030811 35 0.010
Human
regulation of atp metabolic process GO:1903578 5 0.010
Human
microtubule based process GO:0007017 182 0.010

tnt-4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.048
Human
hypertrophic cardiomyopathy DOID:11984 0 0.024
Human
myopathy DOID:423 0 0.024
Human
muscular disease DOID:0080000 0 0.024
Human
heart disease DOID:114 0 0.024
Human
cardiomyopathy DOID:0050700 0 0.024
Human
intrinsic cardiomyopathy DOID:0060036 0 0.024
Human
cardiovascular system disease DOID:1287 0 0.024
Human
musculoskeletal system disease DOID:17 0 0.024
Human
muscle tissue disease DOID:66 0 0.024
Human
dilated cardiomyopathy DOID:12930 0 0.016
Human
nervous system disease DOID:863 0 0.012