Caenorhabditis elegans

75 known processes

skr-1 (CELE_F46A9.5)

Protein SKR-1

skr-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
sex differentiation GO:0007548 909 0.679
genitalia development GO:0048806 741 0.574
regulation of macromolecule metabolic process GO:0060255 421 0.531
developmental process involved in reproduction GO:0003006 1165 0.509
embryo development GO:0009790 3052 0.450
cellular protein metabolic process GO:0044267 279 0.407
Human Yeast
multicellular organismal reproductive process GO:0048609 815 0.405
Worm
hermaphrodite genitalia development GO:0040035 734 0.394
reproductive system development GO:0061458 850 0.369
sexual reproduction GO:0019953 546 0.341
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.319
gamete generation GO:0007276 461 0.314
development of primary sexual characteristics GO:0045137 840 0.312
apoptotic process GO:0006915 478 0.305
reproductive structure development GO:0048608 850 0.241
positive regulation of epithelial cell proliferation GO:0050679 1 0.232
single organism signaling GO:0044700 401 0.231
Fly
post embryonic development GO:0009791 2152 0.229
programmed cell death GO:0012501 500 0.211
regulation of primary metabolic process GO:0080090 292 0.211
regulation of cellular protein metabolic process GO:0032268 75 0.194
embryo development ending in birth or egg hatching GO:0009792 2992 0.189
positive regulation of nucleic acid templated transcription GO:1903508 102 0.186
locomotion GO:0040011 1634 0.182
vesicle mediated transport GO:0016192 852 0.170
endocytosis GO:0006897 819 0.163
cellular biosynthetic process GO:0044249 315 0.159
Fly
receptor mediated endocytosis GO:0006898 715 0.156
multicellular organism reproduction GO:0032504 819 0.156
Worm
positive regulation of macromolecule metabolic process GO:0010604 149 0.155
catabolic process GO:0009056 318 0.155
Human Yeast
organic substance catabolic process GO:1901575 294 0.154
Human Yeast
cellular response to stress GO:0033554 162 0.154
Fly
gonad development GO:0008406 840 0.150
cellular macromolecule biosynthetic process GO:0034645 247 0.147
Fly
cell death GO:0008219 547 0.139
multi organism reproductive process GO:0044703 867 0.136
Worm
transport GO:0006810 1093 0.135
regulation of multicellular organismal process GO:0051239 726 0.135
Fly
establishment of localization GO:0051234 1171 0.134
oviposition GO:0018991 364 0.134
Worm
cellular protein modification process GO:0006464 207 0.131
Human Yeast
protein modification by small protein conjugation or removal GO:0070647 40 0.130
Human Yeast
oogenesis GO:0048477 229 0.129
protein metabolic process GO:0019538 422 0.126
Human Yeast
germ cell development GO:0007281 351 0.124
multicellular organismal aging GO:0010259 812 0.124
regulation of response to stimulus GO:0048583 243 0.121
Fly
female gamete generation GO:0007292 254 0.120
ubiquitin dependent protein catabolic process GO:0006511 32 0.116
Human Yeast
protein modification process GO:0036211 207 0.112
Human Yeast
organelle organization GO:0006996 783 0.111
Human Yeast Worm Fly
regulation of cellular metabolic process GO:0031323 305 0.110
Fly
defense response GO:0006952 296 0.108
Worm
regulation of nitrogen compound metabolic process GO:0051171 222 0.107
positive regulation of gene expression GO:0010628 112 0.106
chromosome organization GO:0051276 104 0.102
Human Yeast Fly
signaling GO:0023052 401 0.102
Fly
single organism reproductive process GO:0044702 1196 0.101
single organism organelle organization GO:1902589 501 0.100
Human Yeast Worm Fly
modification dependent protein catabolic process GO:0019941 32 0.097
Human Yeast
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.094
regulation of macromolecule biosynthetic process GO:0010556 189 0.094
organ development GO:0048513 1102 0.094
fertilization GO:0009566 63 0.092
positive regulation of metabolic process GO:0009893 187 0.089
regulation of protein catabolic process GO:0042176 13 0.088
positive regulation of biosynthetic process GO:0009891 109 0.086
regulation of protein metabolic process GO:0051246 81 0.086
aging GO:0007568 812 0.085
cellular protein catabolic process GO:0044257 37 0.084
Human Yeast
macromolecule modification GO:0043412 218 0.084
Human Yeast
positive regulation of cellular biosynthetic process GO:0031328 109 0.083
cell migration GO:0016477 306 0.082
determination of adult lifespan GO:0008340 812 0.080
response to wounding GO:0009611 4 0.077
response to chemical GO:0042221 356 0.076
Fly
cell development GO:0048468 696 0.076
Fly
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.073
post embryonic organ development GO:0048569 336 0.072
gene expression GO:0010467 412 0.069
cell division GO:0051301 262 0.069
Yeast
regulation of nematode larval development GO:0061062 260 0.068
regulation of developmental growth GO:0048638 389 0.067
Fly
negative regulation of vulval development GO:0040027 206 0.067
reproductive behavior GO:0019098 387 0.066
Worm
regulation of meiotic cell cycle GO:0051445 136 0.065
Worm
regulation of cell cycle process GO:0010564 145 0.065
Yeast Fly
negative regulation of nematode larval development GO:0061064 208 0.064
single organism localization GO:1902578 518 0.063
Worm
digestive system development GO:0055123 122 0.062
cellular catabolic process GO:0044248 199 0.061
Human Yeast
cell fate commitment GO:0045165 139 0.061
regulation of multi organism process GO:0043900 69 0.061
vulval development GO:0040025 333 0.061
meiotic cell cycle process GO:1903046 170 0.060
Worm
regulation of biological quality GO:0065008 741 0.060
Yeast Fly
negative regulation of biological process GO:0048519 567 0.059
regulation of vulval development GO:0040028 248 0.059
cell cycle process GO:0022402 482 0.059
Yeast Worm Fly
regulation of rna biosynthetic process GO:2001141 165 0.058
molting cycle GO:0042303 281 0.058
meiotic cell cycle GO:0051321 335 0.058
Worm
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.057
macromolecule localization GO:0033036 771 0.057
body morphogenesis GO:0010171 620 0.057
organonitrogen compound metabolic process GO:1901564 151 0.056
regulation of gene expression GO:0010468 366 0.056
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.055
regulation of signaling GO:0023051 172 0.055
Fly
organelle fission GO:0048285 363 0.055
Yeast Worm Fly
purine ribonucleoside metabolic process GO:0046128 92 0.055
purine nucleoside metabolic process GO:0042278 92 0.053
growth GO:0040007 562 0.053
Fly
positive regulation of cellular metabolic process GO:0031325 178 0.053
lipid storage GO:0019915 565 0.053
regulation of organelle organization GO:0033043 164 0.052
Yeast Fly
establishment of localization in cell GO:0051649 318 0.052
Worm
cell cycle GO:0007049 526 0.051
Yeast Worm Fly
cellular component movement GO:0006928 388 0.051
aromatic compound biosynthetic process GO:0019438 192 0.049
negative regulation of metabolic process GO:0009892 240 0.049
maintenance of location GO:0051235 580 0.048
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.048
rna biosynthetic process GO:0032774 169 0.047
macromolecule biosynthetic process GO:0009059 250 0.047
Fly
rna metabolic process GO:0016070 228 0.046
proteolysis involved in cellular protein catabolic process GO:0051603 32 0.045
Human Yeast
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 20 0.044
Human Yeast
nucleic acid metabolic process GO:0090304 299 0.043
Fly
cell motility GO:0048870 313 0.043
lipid localization GO:0010876 573 0.043
transcription from rna polymerase ii promoter GO:0006366 149 0.043
heterocycle biosynthetic process GO:0018130 187 0.043
proteolysis GO:0006508 61 0.042
Human Yeast
protein localization GO:0008104 205 0.042
multicellular organismal reproductive behavior GO:0033057 384 0.042
Worm
regulation of cellular component organization GO:0051128 248 0.042
Yeast Fly
response to other organism GO:0051707 101 0.042
Worm
positive regulation of rna biosynthetic process GO:1902680 102 0.041
multi organism reproductive behavior GO:0044705 387 0.041
Worm
phosphate containing compound metabolic process GO:0006796 232 0.040
Fly
regulation of rna metabolic process GO:0051252 173 0.039
localization of cell GO:0051674 313 0.039
transcription dna templated GO:0006351 168 0.039
phagocytosis GO:0006909 115 0.039
death GO:0016265 547 0.038
multi organism behavior GO:0051705 389 0.038
Worm
regulation of cellular biosynthetic process GO:0031326 189 0.037
negative regulation of cellular metabolic process GO:0031324 95 0.037
Fly
protein catabolic process GO:0030163 162 0.037
Human Yeast
modification dependent macromolecule catabolic process GO:0043632 32 0.037
Human Yeast
nucleobase containing compound biosynthetic process GO:0034654 184 0.036
posttranscriptional regulation of gene expression GO:0010608 166 0.035
macromolecule catabolic process GO:0009057 202 0.035
Human Yeast
regulation of cell death GO:0010941 65 0.035
meiotic nuclear division GO:0007126 300 0.035
Worm
single organism transport GO:0044765 447 0.035
nucleobase containing compound metabolic process GO:0006139 406 0.035
Fly
organic cyclic compound catabolic process GO:1901361 119 0.034
regulation of nucleic acid templated transcription GO:1903506 165 0.034
nucleotide catabolic process GO:0009166 77 0.034
developmental maturation GO:0021700 26 0.034
Fly
negative regulation of gene expression GO:0010629 217 0.033
positive regulation of transcription dna templated GO:0045893 102 0.032
biosynthetic process GO:0009058 323 0.032
Fly
negative regulation of multicellular organismal process GO:0051241 236 0.031
Fly
behavior GO:0007610 527 0.031
Worm
anatomical structure formation involved in morphogenesis GO:0048646 250 0.030
positive regulation of multicellular organismal process GO:0051240 417 0.030
response to external biotic stimulus GO:0043207 101 0.030
Worm
purine nucleoside triphosphate metabolic process GO:0009144 87 0.030
regulation of post embryonic development GO:0048580 260 0.029
negative regulation of macromolecule metabolic process GO:0010605 229 0.029
glycosyl compound metabolic process GO:1901657 100 0.029
cellular localization GO:0051641 360 0.028
Worm
organic cyclic compound biosynthetic process GO:1901362 195 0.028
regulation of metabolic process GO:0019222 478 0.028
regulation of cellular response to stress GO:0080135 19 0.028
Fly
mapk cascade GO:0000165 31 0.027
Fly
response to topologically incorrect protein GO:0035966 82 0.027
secretion by cell GO:0032940 138 0.027
regulation of catalytic activity GO:0050790 78 0.027
regulation of developmental process GO:0050793 684 0.027
Fly
macromolecular complex subunit organization GO:0043933 320 0.027
Human Yeast
organonitrogen compound catabolic process GO:1901565 90 0.027
negative regulation of post embryonic development GO:0048581 208 0.026
positive regulation of developmental growth GO:0048639 354 0.026
response to external stimulus GO:0009605 289 0.026
Worm
er nucleus signaling pathway GO:0006984 66 0.026
nucleic acid templated transcription GO:0097659 169 0.025
negative regulation of cellular process GO:0048523 239 0.025
Worm Fly
monovalent inorganic cation homeostasis GO:0055067 6 0.025
Yeast
regulation of reproductive process GO:2000241 66 0.025
signal transduction GO:0007165 317 0.025
Fly
nucleotide metabolic process GO:0009117 108 0.024
organelle assembly GO:0070925 214 0.024
Yeast
regulation of mitotic cell cycle GO:0007346 76 0.023
Yeast Fly
mitotic cell cycle process GO:1903047 194 0.023
Yeast Worm Fly
mitotic nuclear division GO:0007067 89 0.023
Yeast Fly
digestive tract development GO:0048565 122 0.023
regulation of oviposition GO:0046662 43 0.023
regulation of ph GO:0006885 6 0.023
Yeast
regeneration GO:0031099 4 0.022
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.022
positive regulation of growth GO:0045927 369 0.022
cellular response to chemical stimulus GO:0070887 129 0.022
Fly
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.022
organic substance transport GO:0071702 113 0.021
purine ribonucleotide catabolic process GO:0009154 75 0.021
innate immune response GO:0045087 190 0.021
Worm
regulation of nuclear division GO:0051783 115 0.021
Yeast
multicellular organism growth GO:0035264 385 0.021
positive regulation of cellular protein catabolic process GO:1903364 3 0.020
cellular response to unfolded protein GO:0034620 71 0.020
regulation of biosynthetic process GO:0009889 189 0.020
regulation of cellular catabolic process GO:0031329 51 0.020
single organism catabolic process GO:0044712 129 0.020
embryonic morphogenesis GO:0048598 152 0.020
response to unfolded protein GO:0006986 71 0.020
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.020
regulation of apoptotic signaling pathway GO:2001233 1 0.020
pattern specification process GO:0007389 59 0.020
negative regulation of transcription dna templated GO:0045892 53 0.020
positive regulation of developmental process GO:0051094 408 0.019
regulation of multicellular organismal development GO:2000026 317 0.019
Fly
regulation of localization GO:0032879 194 0.019
regulation of protein ubiquitination GO:0031396 3 0.019
regulation of behavior GO:0050795 97 0.019
regulation of signal transduction GO:0009966 135 0.018
Fly
multi multicellular organism process GO:0044706 390 0.018
Worm
cellular nitrogen compound biosynthetic process GO:0044271 192 0.018
regulation of programmed cell death GO:0043067 50 0.018
defense response to other organism GO:0098542 100 0.018
Worm
regulation of growth GO:0040008 409 0.018
Fly
negative regulation of rna biosynthetic process GO:1902679 53 0.018
protein complex assembly GO:0006461 186 0.017
Yeast
regulation of cell division GO:0051302 142 0.017
Yeast
positive regulation of multicellular organism growth GO:0040018 352 0.017
epithelial tube morphogenesis GO:0060562 1 0.017
response to biotic stimulus GO:0009607 101 0.017
Worm
cellular macromolecular complex assembly GO:0034622 184 0.017
Yeast
tube development GO:0035295 126 0.017
oocyte axis specification GO:0007309 2 0.017
cellular component assembly GO:0022607 293 0.016
Yeast Fly
ribonucleotide metabolic process GO:0009259 99 0.016
cell recognition GO:0008037 85 0.016
cellular macromolecule catabolic process GO:0044265 73 0.016
Human Yeast
cell type specific apoptotic process GO:0097285 4 0.016
axon development GO:0061564 163 0.016
regulation of cellular ph GO:0030641 4 0.016
Yeast
gene silencing by rna GO:0031047 143 0.016
negative regulation of biosynthetic process GO:0009890 65 0.016
intracellular signal transduction GO:0035556 96 0.016
Fly
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 1 0.016
regulation of anatomical structure size GO:0090066 46 0.015
nervous system development GO:0007399 253 0.015
Fly
chromosome segregation GO:0007059 180 0.015
Worm
purine ribonucleoside catabolic process GO:0046130 75 0.015
purine nucleotide metabolic process GO:0006163 95 0.015
ribose phosphate metabolic process GO:0019693 99 0.015
phosphorylation GO:0016310 116 0.015
Fly
protein complex biogenesis GO:0070271 186 0.015
Yeast
establishment of organelle localization GO:0051656 123 0.015
Worm
negative regulation of developmental process GO:0051093 227 0.015
Fly
muscle structure development GO:0061061 191 0.015
organophosphate catabolic process GO:0046434 81 0.015
single fertilization GO:0007338 61 0.015
inductive cell migration GO:0040039 145 0.015
cytoskeleton organization GO:0007010 339 0.014
Yeast Worm Fly
ribonucleoside catabolic process GO:0042454 77 0.014
protein ubiquitination GO:0016567 25 0.014
Human Yeast
neuromuscular junction development GO:0007528 2 0.014
Fly
ribonucleoprotein complex assembly GO:0022618 4 0.014
secretion GO:0046903 147 0.014
ribonucleoside triphosphate metabolic process GO:0009199 87 0.014
head development GO:0060322 1 0.014
signal transduction by phosphorylation GO:0023014 31 0.014
Fly
positive regulation of protein transport GO:0051222 4 0.014
regulation of multicellular organism growth GO:0040014 373 0.014
regulation of protein targeting GO:1903533 3 0.014
regulation of gene expression epigenetic GO:0040029 163 0.014
regulation of epithelial cell proliferation GO:0050678 1 0.013
neurological system process GO:0050877 53 0.013
purine ribonucleotide metabolic process GO:0009150 95 0.013
cellular response to abiotic stimulus GO:0071214 4 0.013
ras protein signal transduction GO:0007265 31 0.013
carbohydrate derivative metabolic process GO:1901135 141 0.013
sex determination GO:0007530 60 0.013
cellular component biogenesis GO:0044085 297 0.013
Yeast Fly
nuclear migration GO:0007097 54 0.013
regulation of response to stress GO:0080134 28 0.013
Fly
pronuclear migration GO:0035046 51 0.013
negative regulation of cellular biosynthetic process GO:0031327 65 0.013
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.012
regulation of nucleocytoplasmic transport GO:0046822 3 0.012
negative regulation of signaling GO:0023057 61 0.012
Fly
neuron differentiation GO:0030182 217 0.012
Fly
positive regulation of intracellular transport GO:0032388 2 0.012
gene silencing GO:0016458 143 0.012
regulation of cellular amine metabolic process GO:0033238 0 0.012
positive regulation of apoptotic process GO:0043065 17 0.012
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 5 0.012
purine containing compound catabolic process GO:0072523 75 0.012
small molecule metabolic process GO:0044281 186 0.012
developmental growth GO:0048589 412 0.012
Fly
negative regulation of response to external stimulus GO:0032102 3 0.012
nucleobase containing small molecule metabolic process GO:0055086 115 0.012
regulation of lipid metabolic process GO:0019216 4 0.012
regulation of anatomical structure morphogenesis GO:0022603 51 0.012
phosphorus metabolic process GO:0006793 232 0.012
Fly
negative regulation of rna metabolic process GO:0051253 53 0.012
phagosome maturation involved in apoptotic cell clearance GO:0090386 13 0.012
actin filament based process GO:0030029 191 0.011
axon guidance GO:0007411 82 0.011
response to organic substance GO:0010033 131 0.011
Fly
ph reduction GO:0045851 2 0.011
Yeast
oocyte differentiation GO:0009994 45 0.011
proteasomal protein catabolic process GO:0010498 20 0.011
Human Yeast
regulation of phosphate metabolic process GO:0019220 81 0.011
Fly
cellular amino acid metabolic process GO:0006520 15 0.011
negative regulation of programmed cell death GO:0043069 19 0.011
Fly
purine nucleotide catabolic process GO:0006195 75 0.011
positive regulation of protein metabolic process GO:0051247 45 0.011
rna localization GO:0006403 3 0.011
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.011
neuron projection guidance GO:0097485 82 0.011
regulation of cell size GO:0008361 30 0.011
cell proliferation GO:0008283 116 0.011
Worm
macromolecular complex assembly GO:0065003 193 0.011
Yeast
negative regulation of cell communication GO:0010648 61 0.011
Fly
canonical wnt signaling pathway GO:0060070 3 0.011
epithelial cell proliferation GO:0050673 1 0.011
endoplasmic reticulum unfolded protein response GO:0030968 66 0.011
cellular component morphogenesis GO:0032989 318 0.011
cellular response to topologically incorrect protein GO:0035967 76 0.011
regulation of cell cycle GO:0051726 194 0.011
Yeast Worm Fly
organophosphate metabolic process GO:0019637 125 0.011
regulation of cell migration GO:0030334 55 0.011
positive regulation of cell migration GO:0030335 3 0.010
purine nucleoside catabolic process GO:0006152 75 0.010
regulation of cellular ketone metabolic process GO:0010565 3 0.010
organelle localization GO:0051640 127 0.010
Worm
regulation of canonical wnt signaling pathway GO:0060828 1 0.010

skr-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.071
disease of cellular proliferation DOID:14566 0 0.011