Caenorhabditis elegans

58 known processes

spg-7 (CELE_Y47G6A.10)

Protein SPG-7

spg-7 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
gonad development GO:0008406 840 0.272
post embryonic development GO:0009791 2152 0.270
establishment of localization GO:0051234 1171 0.262
embryo development GO:0009790 3052 0.231
embryo development ending in birth or egg hatching GO:0009792 2992 0.225
single organism reproductive process GO:0044702 1196 0.219
organ development GO:0048513 1102 0.215
developmental process involved in reproduction GO:0003006 1165 0.175
regulation of metabolic process GO:0019222 478 0.175
reproductive system development GO:0061458 850 0.164
reproductive structure development GO:0048608 850 0.160
development of primary sexual characteristics GO:0045137 840 0.156
locomotion GO:0040011 1634 0.141
transport GO:0006810 1093 0.138
endocytosis GO:0006897 819 0.138
genitalia development GO:0048806 741 0.124
vesicle mediated transport GO:0016192 852 0.116
hermaphrodite genitalia development GO:0040035 734 0.114
sex differentiation GO:0007548 909 0.110
organelle organization GO:0006996 783 0.108
Mouse
receptor mediated endocytosis GO:0006898 715 0.108
cell cycle GO:0007049 526 0.101
single organism localization GO:1902578 518 0.098
single organism transport GO:0044765 447 0.095
body morphogenesis GO:0010171 620 0.095
negative regulation of biological process GO:0048519 567 0.091
multicellular organismal reproductive process GO:0048609 815 0.085
growth GO:0040007 562 0.084
Mouse
multicellular organism reproduction GO:0032504 819 0.081
multi organism reproductive process GO:0044703 867 0.080
apoptotic process GO:0006915 478 0.077
multicellular organismal aging GO:0010259 812 0.074
cell motility GO:0048870 313 0.068
ribosome biogenesis GO:0042254 4 0.067
macromolecule localization GO:0033036 771 0.066
cell death GO:0008219 547 0.066
cellular component biogenesis GO:0044085 297 0.063
programmed cell death GO:0012501 500 0.062
nucleobase containing compound metabolic process GO:0006139 406 0.062
phosphorus metabolic process GO:0006793 232 0.062
determination of adult lifespan GO:0008340 812 0.062
phosphate containing compound metabolic process GO:0006796 232 0.061
regulation of developmental process GO:0050793 684 0.061
Mouse
protein metabolic process GO:0019538 422 0.060
Mouse
gene expression GO:0010467 412 0.058
Mouse
maintenance of location GO:0051235 580 0.058
negative regulation of metabolic process GO:0009892 240 0.058
sexual reproduction GO:0019953 546 0.058
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.057
lipid localization GO:0010876 573 0.056
regulation of biological quality GO:0065008 741 0.056
Mouse
regulation of cellular metabolic process GO:0031323 305 0.056
lipid storage GO:0019915 565 0.055
cell cycle process GO:0022402 482 0.055
regulation of gene expression GO:0010468 366 0.054
nucleobase containing small molecule metabolic process GO:0055086 115 0.053
developmental growth GO:0048589 412 0.052
Mouse
aging GO:0007568 812 0.052
cell development GO:0048468 696 0.052
Mouse
regulation of macromolecule metabolic process GO:0060255 421 0.052
organic substance catabolic process GO:1901575 294 0.051
cell migration GO:0016477 306 0.051
regulation of multicellular organismal process GO:0051239 726 0.049
Mouse
rrna metabolic process GO:0016072 3 0.047
germ cell development GO:0007281 351 0.047
single organism organelle organization GO:1902589 501 0.047
Mouse
catabolic process GO:0009056 318 0.047
regulation of primary metabolic process GO:0080090 292 0.046
death GO:0016265 547 0.045
Mouse
signal transduction GO:0007165 317 0.045
cellular localization GO:0051641 360 0.044
behavior GO:0007610 527 0.044
positive regulation of multicellular organismal process GO:0051240 417 0.043
localization of cell GO:0051674 313 0.043
vulval development GO:0040025 333 0.043
biosynthetic process GO:0009058 323 0.043
regulation of growth GO:0040008 409 0.042
Mouse
positive regulation of developmental process GO:0051094 408 0.041
organelle fission GO:0048285 363 0.041
rna metabolic process GO:0016070 228 0.040
establishment of localization in cell GO:0051649 318 0.040
cellular component movement GO:0006928 388 0.040
organophosphate metabolic process GO:0019637 125 0.040
small molecule metabolic process GO:0044281 186 0.039
cell division GO:0051301 262 0.039
gamete generation GO:0007276 461 0.039
response to wounding GO:0009611 4 0.038
regulation of developmental growth GO:0048638 389 0.038
Mouse
organic substance biosynthetic process GO:1901576 323 0.038
reproductive behavior GO:0019098 387 0.037
multicellular organismal reproductive behavior GO:0033057 384 0.037
regulation of cellular component organization GO:0051128 248 0.037
positive regulation of multicellular organism growth GO:0040018 352 0.037
negative regulation of cellular process GO:0048523 239 0.037
multicellular organism growth GO:0035264 385 0.036
Mouse
multi organism reproductive behavior GO:0044705 387 0.036
cellular component assembly GO:0022607 293 0.036
positive regulation of cellular process GO:0048522 332 0.036
female gamete generation GO:0007292 254 0.035
post embryonic organ development GO:0048569 336 0.035
signaling GO:0023052 401 0.035
oogenesis GO:0048477 229 0.034
membrane organization GO:0061024 135 0.034
Mouse
meiotic cell cycle GO:0051321 335 0.034
carbohydrate derivative metabolic process GO:1901135 141 0.034
cellular protein metabolic process GO:0044267 279 0.034
Mouse
regulation of nitrogen compound metabolic process GO:0051171 222 0.034
response to external stimulus GO:0009605 289 0.033
Mouse
multi multicellular organism process GO:0044706 390 0.033
positive regulation of developmental growth GO:0048639 354 0.033
molting cycle GO:0042303 281 0.033
multi organism behavior GO:0051705 389 0.033
regulation of vulval development GO:0040028 248 0.032
positive regulation of growth GO:0045927 369 0.032
macromolecule catabolic process GO:0009057 202 0.032
regulation of nematode larval development GO:0061062 260 0.032
purine nucleoside metabolic process GO:0042278 92 0.032
oviposition GO:0018991 364 0.032
nucleoside metabolic process GO:0009116 99 0.031
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.031
macromolecular complex subunit organization GO:0043933 320 0.030
nervous system development GO:0007399 253 0.030
Mouse
single organism signaling GO:0044700 401 0.030
cellular component morphogenesis GO:0032989 318 0.030
Mouse
nucleic acid metabolic process GO:0090304 299 0.030
posttranscriptional gene silencing GO:0016441 143 0.029
nucleotide metabolic process GO:0009117 108 0.029
cellular protein modification process GO:0006464 207 0.029
negative regulation of macromolecule metabolic process GO:0010605 229 0.029
regulation of multicellular organism growth GO:0040014 373 0.029
Mouse
ribonucleoside triphosphate metabolic process GO:0009199 87 0.028
ribonucleotide metabolic process GO:0009259 99 0.028
organonitrogen compound metabolic process GO:1901564 151 0.028
cellular catabolic process GO:0044248 199 0.028
organic cyclic compound biosynthetic process GO:1901362 195 0.028
nucleobase containing compound biosynthetic process GO:0034654 184 0.028
ribose phosphate metabolic process GO:0019693 99 0.027
regulation of post embryonic development GO:0048580 260 0.027
regulation of multicellular organismal development GO:2000026 317 0.027
purine nucleoside triphosphate metabolic process GO:0009144 87 0.027
nucleoside triphosphate metabolic process GO:0009141 87 0.027
generation of neurons GO:0048699 235 0.027
Mouse
negative regulation of gene expression GO:0010629 217 0.026
regulation of phosphorus metabolic process GO:0051174 81 0.026
purine ribonucleoside metabolic process GO:0046128 92 0.026
protein localization GO:0008104 205 0.026
meiotic nuclear division GO:0007126 300 0.026
regulation of signaling GO:0023051 172 0.026
response to chemical GO:0042221 356 0.026
cytoskeleton organization GO:0007010 339 0.026
cellular macromolecule biosynthetic process GO:0034645 247 0.025
organelle assembly GO:0070925 214 0.025
regulation of cell cycle GO:0051726 194 0.025
protein catabolic process GO:0030163 162 0.025
protein complex subunit organization GO:0071822 280 0.025
regulation of signal transduction GO:0009966 135 0.024
neurogenesis GO:0022008 236 0.024
Mouse
protein modification process GO:0036211 207 0.024
heterocycle catabolic process GO:0046700 119 0.024
ribonucleotide catabolic process GO:0009261 75 0.024
regulation of gene expression epigenetic GO:0040029 163 0.024
regulation of organelle organization GO:0033043 164 0.024
neuron differentiation GO:0030182 217 0.023
Mouse
muscle tissue development GO:0060537 1 0.023
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.023
axon development GO:0061564 163 0.023
Mouse
nucleoside phosphate metabolic process GO:0006753 108 0.023
glycosyl compound metabolic process GO:1901657 100 0.023
ion transport GO:0006811 113 0.023
purine containing compound metabolic process GO:0072521 95 0.022
rna interference GO:0016246 137 0.022
regulation of biosynthetic process GO:0009889 189 0.022
cell projection organization GO:0030030 231 0.022
Mouse
purine nucleoside triphosphate catabolic process GO:0009146 72 0.022
gene silencing by rna GO:0031047 143 0.022
macromolecule modification GO:0043412 218 0.022
regulation of cell communication GO:0010646 176 0.022
inductive cell migration GO:0040039 145 0.022
purine nucleoside catabolic process GO:0006152 75 0.022
macromolecular complex assembly GO:0065003 193 0.022
cellular nitrogen compound catabolic process GO:0044270 119 0.021
regulation of phosphate metabolic process GO:0019220 81 0.021
positive regulation of vulval development GO:0040026 52 0.021
regulation of molecular function GO:0065009 89 0.021
regulation of cell division GO:0051302 142 0.021
neuron development GO:0048666 199 0.021
Mouse
actin filament based process GO:0030029 191 0.021
regulation of localization GO:0032879 194 0.021
head development GO:0060322 1 0.021
gene silencing GO:0016458 143 0.021
carbohydrate derivative catabolic process GO:1901136 82 0.021
regulation of catalytic activity GO:0050790 78 0.021
nucleotide catabolic process GO:0009166 77 0.021
cellular nitrogen compound biosynthetic process GO:0044271 192 0.021
anatomical structure formation involved in morphogenesis GO:0048646 250 0.021
posttranscriptional gene silencing by rna GO:0035194 143 0.020
purine ribonucleoside catabolic process GO:0046130 75 0.020
purine nucleotide metabolic process GO:0006163 95 0.020
mitotic cell cycle process GO:1903047 194 0.020
ribonucleoside metabolic process GO:0009119 98 0.020
organic cyclic compound catabolic process GO:1901361 119 0.020
nucleoside phosphate catabolic process GO:1901292 77 0.019
protein complex biogenesis GO:0070271 186 0.019
negative regulation of post embryonic development GO:0048581 208 0.019
nucleoside triphosphate catabolic process GO:0009143 72 0.019
purine ribonucleotide catabolic process GO:0009154 75 0.019
negative regulation of developmental process GO:0051093 227 0.019
nucleoside catabolic process GO:0009164 78 0.019
posttranscriptional regulation of gene expression GO:0010608 166 0.019
sensory organ morphogenesis GO:0090596 2 0.019
secretion by cell GO:0032940 138 0.019
negative regulation of multicellular organismal process GO:0051241 236 0.019
regulation of nuclear division GO:0051783 115 0.019
skeletal muscle organ development GO:0060538 3 0.019
response to heat GO:0009408 50 0.019
intracellular signal transduction GO:0035556 96 0.019
organelle localization GO:0051640 127 0.018
cellular biosynthetic process GO:0044249 315 0.018
actin cytoskeleton organization GO:0030036 184 0.018
regulation of nucleic acid templated transcription GO:1903506 165 0.018
defense response GO:0006952 296 0.018
negative regulation of vulval development GO:0040027 206 0.018
single organism catabolic process GO:0044712 129 0.018
protein complex assembly GO:0006461 186 0.018
aromatic compound biosynthetic process GO:0019438 192 0.018
neuromuscular junction development GO:0007528 2 0.018
Mouse
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.018
regulation of cell cycle process GO:0010564 145 0.018
positive regulation of cellular metabolic process GO:0031325 178 0.018
regulation of cytoplasmic transport GO:1903649 3 0.018
epithelial tube morphogenesis GO:0060562 1 0.017
regulation of meiosis GO:0040020 94 0.017
purine ribonucleotide metabolic process GO:0009150 95 0.017
ribonucleoprotein complex assembly GO:0022618 4 0.017
immune response GO:0006955 192 0.017
regeneration GO:0031099 4 0.017
negative regulation of nematode larval development GO:0061064 208 0.017
macromolecule biosynthetic process GO:0009059 250 0.017
regulation of meiotic cell cycle GO:0051445 136 0.017
regulation of transcription dna templated GO:0006355 164 0.017
cellular protein complex assembly GO:0043623 178 0.017
organic substance transport GO:0071702 113 0.017
regulation of cellular biosynthetic process GO:0031326 189 0.017
cell proliferation GO:0008283 116 0.017
rrna processing GO:0006364 3 0.016
phagocytosis GO:0006909 115 0.016
single organism cellular localization GO:1902580 72 0.016
cellular macromolecular complex assembly GO:0034622 184 0.016
cellular response to stress GO:0033554 162 0.016
regulation of synapse assembly GO:0051963 2 0.016
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.016
single organism biosynthetic process GO:0044711 91 0.016
regulation of locomotion GO:0040012 161 0.016
organophosphate catabolic process GO:0046434 81 0.016
regulation of apoptotic signaling pathway GO:2001233 1 0.016
purine containing compound catabolic process GO:0072523 75 0.016
nucleobase containing compound catabolic process GO:0034655 114 0.016
microtubule based process GO:0007017 182 0.016
ribonucleoside catabolic process GO:0042454 77 0.016
membrane invagination GO:0010324 98 0.015
apoptotic cell clearance GO:0043277 111 0.015
cellular response to abiotic stimulus GO:0071214 4 0.015
neuron projection development GO:0031175 187 0.015
Mouse
nucleic acid templated transcription GO:0097659 169 0.015
rna biosynthetic process GO:0032774 169 0.015
establishment of organelle localization GO:0051656 123 0.015
response to abiotic stimulus GO:0009628 152 0.015
regulation of nucleocytoplasmic transport GO:0046822 3 0.015
establishment or maintenance of cell polarity GO:0007163 63 0.015
regulation of macromolecule biosynthetic process GO:0010556 189 0.015
aromatic compound catabolic process GO:0019439 116 0.015
protein phosphorylation GO:0006468 85 0.015
transcription dna templated GO:0006351 168 0.015
heterocycle biosynthetic process GO:0018130 187 0.015
purine nucleotide catabolic process GO:0006195 75 0.015
secretion GO:0046903 147 0.015
response to organic substance GO:0010033 131 0.015
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.014
phosphorylation GO:0016310 116 0.014
regulation of cell proliferation GO:0042127 105 0.014
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.014
regulation of response to stimulus GO:0048583 243 0.014
innate immune response GO:0045087 190 0.014
ribonucleoside monophosphate metabolic process GO:0009161 45 0.014
positive regulation of neurogenesis GO:0050769 4 0.014
purine nucleoside monophosphate metabolic process GO:0009126 43 0.014
collagen and cuticulin based cuticle development GO:0040002 99 0.014
positive regulation of neuron differentiation GO:0045666 4 0.014
engulfment of apoptotic cell GO:0043652 94 0.014
response to external biotic stimulus GO:0043207 101 0.014
neuron projection morphogenesis GO:0048812 114 0.014
Mouse
positive regulation of intracellular transport GO:0032388 2 0.014
regulation of rna metabolic process GO:0051252 173 0.014
cell type specific apoptotic process GO:0097285 4 0.014
axonogenesis GO:0007409 102 0.014
Mouse
negative regulation of neurogenesis GO:0050768 4 0.014
positive regulation of cell migration GO:0030335 3 0.014
cuticle development GO:0042335 100 0.014
regulation of lipid metabolic process GO:0019216 4 0.013
muscle cell development GO:0055001 158 0.013
Mouse
positive regulation of macromolecule metabolic process GO:0010604 149 0.013
positive regulation of nematode larval development GO:0061063 54 0.013
organonitrogen compound catabolic process GO:1901565 90 0.013
muscle structure development GO:0061061 191 0.013
Mouse
adult behavior GO:0030534 3 0.013
regulation of cellular ketone metabolic process GO:0010565 3 0.013
negative regulation of cellular metabolic process GO:0031324 95 0.013
mitotic nuclear division GO:0007067 89 0.013
myosin filament organization GO:0031033 138 0.013
cellular response to chemical stimulus GO:0070887 129 0.013
mitotic spindle organization GO:0007052 81 0.013
cellular component assembly involved in morphogenesis GO:0010927 183 0.013
muscle cell differentiation GO:0042692 171 0.013
Mouse
ribonucleoside triphosphate catabolic process GO:0009203 72 0.013
taxis GO:0042330 128 0.013
phagocytosis engulfment GO:0006911 98 0.013
response to temperature stimulus GO:0009266 66 0.013
striated muscle cell development GO:0055002 157 0.013
Mouse
actomyosin structure organization GO:0031032 154 0.013
positive regulation of metabolic process GO:0009893 187 0.013
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.013
Mouse
tissue development GO:0009888 112 0.013
single fertilization GO:0007338 61 0.013
organic acid metabolic process GO:0006082 47 0.013
response to biotic stimulus GO:0009607 101 0.012
myosin filament assembly GO:0031034 138 0.012
myofibril assembly GO:0030239 154 0.012
intracellular transport GO:0046907 77 0.012
single organism intracellular transport GO:1902582 70 0.012
synaptic growth at neuromuscular junction GO:0051124 1 0.012
glycosyl compound catabolic process GO:1901658 79 0.012
regulation of cellular amino acid metabolic process GO:0006521 0 0.012
cellular macromolecule catabolic process GO:0044265 73 0.012
oxoacid metabolic process GO:0043436 47 0.012
spindle organization GO:0007051 92 0.012
cytokinesis GO:0000910 80 0.012
canonical wnt signaling pathway GO:0060070 3 0.012
cellular amine metabolic process GO:0044106 15 0.012
nucleoside monophosphate metabolic process GO:0009123 46 0.012
regulation of cellular amine metabolic process GO:0033238 0 0.012
regulation of organ morphogenesis GO:2000027 4 0.012
chromosome segregation GO:0007059 180 0.012
regulation of response to wounding GO:1903034 1 0.012
cell recognition GO:0008037 85 0.012
positive regulation of post embryonic development GO:0048582 54 0.012
protein oligomerization GO:0051259 4 0.012
dauer larval development GO:0040024 92 0.012
regulation of protein targeting GO:1903533 3 0.012
striated muscle myosin thick filament assembly GO:0071688 138 0.012
amine metabolic process GO:0009308 15 0.012
regulation of protein import into nucleus GO:0042306 3 0.011
epithelial cell proliferation GO:0050673 1 0.011
meiotic cell cycle process GO:1903046 170 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.011
guanosine containing compound metabolic process GO:1901068 49 0.011
rna localization GO:0006403 3 0.011
axonal fasciculation GO:0007413 79 0.011
regulation of intracellular signal transduction GO:1902531 77 0.011
cell part morphogenesis GO:0032990 152 0.011
Mouse
response to other organism GO:0051707 101 0.011
response to acid chemical GO:0001101 4 0.011
neuron recognition GO:0008038 83 0.011
positive regulation of protein transport GO:0051222 4 0.011
regulation of rna biosynthetic process GO:2001141 165 0.011
rho protein signal transduction GO:0007266 2 0.011
gtp catabolic process GO:0006184 46 0.011
meiotic chromosome segregation GO:0045132 139 0.011
carboxylic acid metabolic process GO:0019752 34 0.011
embryonic morphogenesis GO:0048598 152 0.011
adult locomotory behavior GO:0008344 1 0.011
establishment of protein localization to membrane GO:0090150 3 0.011
cell morphogenesis involved in differentiation GO:0000904 112 0.010
Mouse
hatching GO:0035188 48 0.010
positive regulation of rna biosynthetic process GO:1902680 102 0.010
response to inorganic substance GO:0010035 50 0.010
cell cycle g1 s phase transition GO:0044843 2 0.010
cellular amino acid metabolic process GO:0006520 15 0.010
cellular response to organic substance GO:0071310 119 0.010
cell surface receptor signaling pathway GO:0007166 149 0.010
fertilization GO:0009566 63 0.010
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.010

spg-7 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.015
Human
disease of cellular proliferation DOID:14566 0 0.011
cancer DOID:162 0 0.011
nervous system disease DOID:863 0 0.011
Human