Caenorhabditis elegans

101 known processes

pat-2 (CELE_F54F2.1)

Protein PAT-2

pat-2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
hermaphrodite genitalia development GO:0040035 734 0.432
Worm
establishment of localization GO:0051234 1171 0.418
cell motility GO:0048870 313 0.417
organelle assembly GO:0070925 214 0.410
Fly
single organism organelle organization GO:1902589 501 0.386
Fly
organelle organization GO:0006996 783 0.386
Fly
receptor mediated endocytosis GO:0006898 715 0.382
striated muscle contraction involved in embryonic body morphogenesis GO:0061199 13 0.381
multicellular organismal reproductive process GO:0048609 815 0.349
post embryonic development GO:0009791 2152 0.335
muscle cell differentiation GO:0042692 171 0.327
Mouse Fly
locomotion GO:0040011 1634 0.308
regulation of developmental process GO:0050793 684 0.305
Human Fly
muscle structure development GO:0061061 191 0.300
Mouse Fly
cellular component morphogenesis GO:0032989 318 0.300
Human Zebrafish Fly
reproductive structure development GO:0048608 850 0.298
Worm
transport GO:0006810 1093 0.288
actin filament based process GO:0030029 191 0.282
Fly
actomyosin structure organization GO:0031032 154 0.250
Fly
striated muscle cell development GO:0055002 157 0.246
Fly
macromolecular complex subunit organization GO:0043933 320 0.246
Fly
single organism reproductive process GO:0044702 1196 0.244
Worm Fly
cell development GO:0048468 696 0.240
Human Zebrafish Worm Fly
single organism signaling GO:0044700 401 0.237
muscle tissue development GO:0060537 1 0.237
Mouse
myofibril assembly GO:0030239 154 0.229
Fly
determination of adult lifespan GO:0008340 812 0.228
muscle organ morphogenesis GO:0048644 4 0.227
membrane organization GO:0061024 135 0.227
sex differentiation GO:0007548 909 0.217
Worm
anatomical structure formation involved in morphogenesis GO:0048646 250 0.210
Human Zebrafish Worm Fly
muscle system process GO:0003012 43 0.202
cytoskeleton organization GO:0007010 339 0.202
Fly
organ development GO:0048513 1102 0.201
Zebrafish Mouse Worm Fly
death GO:0016265 547 0.199
Human Mouse
chemotaxis GO:0006935 120 0.193
Human Fly
vesicle mediated transport GO:0016192 852 0.191
axon development GO:0061564 163 0.184
Worm Fly
growth GO:0040007 562 0.179
Human
developmental process involved in reproduction GO:0003006 1165 0.175
Worm Fly
body morphogenesis GO:0010171 620 0.175
organic substance biosynthetic process GO:1901576 323 0.175
Human Mouse
embryo development ending in birth or egg hatching GO:0009792 2992 0.174
cellular macromolecular complex assembly GO:0034622 184 0.174
multicellular organismal aging GO:0010259 812 0.167
embryonic morphogenesis GO:0048598 152 0.162
cell surface receptor signaling pathway GO:0007166 149 0.159
Human Mouse
cellular protein complex assembly GO:0043623 178 0.157
development of primary sexual characteristics GO:0045137 840 0.157
Worm
cellular component assembly involved in morphogenesis GO:0010927 183 0.156
Fly
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.153
single organism localization GO:1902578 518 0.150
cellular component assembly GO:0022607 293 0.147
Zebrafish Mouse Fly
oviposition GO:0018991 364 0.145
regulation of multicellular organismal process GO:0051239 726 0.145
cellular response to organic substance GO:0071310 119 0.141
Mouse
muscle cell development GO:0055001 158 0.139
Fly
cell cycle GO:0007049 526 0.138
positive regulation of multicellular organism growth GO:0040018 352 0.135
genitalia development GO:0048806 741 0.134
Worm
positive regulation of growth GO:0045927 369 0.134
cell death GO:0008219 547 0.131
Human Mouse
organ morphogenesis GO:0009887 67 0.131
Zebrafish Mouse Worm Fly
embryo development GO:0009790 3052 0.128
cellular component biogenesis GO:0044085 297 0.124
Zebrafish Mouse Fly
signaling GO:0023052 401 0.124
sexual reproduction GO:0019953 546 0.118
Fly
striated muscle myosin thick filament assembly GO:0071688 138 0.118
neuron projection development GO:0031175 187 0.112
Worm Fly
protein complex subunit organization GO:0071822 280 0.111
Fly
macromolecule localization GO:0033036 771 0.108
Human Mouse Fly
protein catabolic process GO:0030163 162 0.106
behavior GO:0007610 527 0.106
cellular component movement GO:0006928 388 0.104
myosin filament assembly GO:0031034 138 0.103
neuron development GO:0048666 199 0.103
Worm Fly
regulation of cell communication GO:0010646 176 0.103
Human Mouse
positive regulation of multicellular organismal process GO:0051240 417 0.102
cell cycle process GO:0022402 482 0.101
generation of neurons GO:0048699 235 0.098
Worm Fly
negative regulation of cellular process GO:0048523 239 0.097
Human
regulation of phosphorus metabolic process GO:0051174 81 0.097
Human
cell adhesion GO:0007155 21 0.095
Human Mouse Worm Fly
striated muscle cell differentiation GO:0051146 158 0.094
Fly
actin cytoskeleton organization GO:0030036 184 0.093
Fly
developmental growth GO:0048589 412 0.092
regulation of metabolic process GO:0019222 478 0.090
Human Mouse
multicellular organism growth GO:0035264 385 0.089
tissue morphogenesis GO:0048729 65 0.089
Human Worm
apoptotic process GO:0006915 478 0.089
Human Mouse
post embryonic organ development GO:0048569 336 0.087
Fly
neuron projection guidance GO:0097485 82 0.087
Fly
engulfment of apoptotic cell GO:0043652 94 0.086
apoptotic cell clearance GO:0043277 111 0.086
response to organic substance GO:0010033 131 0.085
Mouse
regulation of multicellular organism growth GO:0040014 373 0.084
neurogenesis GO:0022008 236 0.084
Worm Fly
inductive cell migration GO:0040039 145 0.083
aging GO:0007568 812 0.082
regulation of signal transduction GO:0009966 135 0.082
Human Mouse
lipid storage GO:0019915 565 0.078
Human
gamete generation GO:0007276 461 0.078
Fly
positive regulation of developmental process GO:0051094 408 0.077
positive regulation of locomotion GO:0040017 42 0.075
regulation of phosphate metabolic process GO:0019220 81 0.073
Human
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.073
Fly
endocytosis GO:0006897 819 0.073
regulation of biological quality GO:0065008 741 0.073
Human Zebrafish Fly
muscle organ development GO:0007517 26 0.071
Fly
multicellular organismal reproductive behavior GO:0033057 384 0.070
macromolecular complex assembly GO:0065003 193 0.069
cell projection morphogenesis GO:0048858 148 0.069
Fly
nervous system development GO:0007399 253 0.066
Worm Fly
protein complex biogenesis GO:0070271 186 0.066
neuron differentiation GO:0030182 217 0.066
Worm Fly
tube development GO:0035295 126 0.065
Human Zebrafish Worm
multi multicellular organism process GO:0044706 390 0.064
reproductive behavior GO:0019098 387 0.064
cellular protein modification process GO:0006464 207 0.063
Human
maintenance of location GO:0051235 580 0.063
Human Fly
regulation of growth GO:0040008 409 0.063
female gamete generation GO:0007292 254 0.063
Fly
regulation of multicellular organismal development GO:2000026 317 0.063
gonad development GO:0008406 840 0.062
Worm
multi organism behavior GO:0051705 389 0.062
meiotic nuclear division GO:0007126 300 0.062
digestive system development GO:0055123 122 0.061
Human Zebrafish Worm
response to chemical GO:0042221 356 0.061
Human Mouse Fly
regulation of nitrogen compound metabolic process GO:0051171 222 0.061
Mouse
regulation of cellular component organization GO:0051128 248 0.061
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.060
Fly
head development GO:0060322 1 0.059
cellular protein metabolic process GO:0044267 279 0.059
Human
regulation of cell migration GO:0030334 55 0.059
Mouse
phagocytosis GO:0006909 115 0.059
multi organism reproductive process GO:0044703 867 0.058
axonogenesis GO:0007409 102 0.058
Fly
tissue development GO:0009888 112 0.057
Human Zebrafish Mouse Worm Fly
macromolecule biosynthetic process GO:0009059 250 0.056
Human Mouse
positive regulation of developmental growth GO:0048639 354 0.056
regulation of cellular metabolic process GO:0031323 305 0.056
Human Mouse
cellular response to chemical stimulus GO:0070887 129 0.056
Mouse
skeletal muscle organ development GO:0060538 3 0.054
Fly
single organism transport GO:0044765 447 0.054
negative regulation of developmental process GO:0051093 227 0.054
Human
organelle fission GO:0048285 363 0.054
digestive tract morphogenesis GO:0048546 76 0.054
Human Zebrafish Worm
negative regulation of biological process GO:0048519 567 0.053
Human
reproductive system development GO:0061458 850 0.053
Worm
taxis GO:0042330 128 0.052
Human Fly
lipid localization GO:0010876 573 0.052
Human
meiotic cell cycle GO:0051321 335 0.052
digestive tract development GO:0048565 122 0.051
Human Zebrafish Worm
myosin filament organization GO:0031033 138 0.051
positive regulation of cellular process GO:0048522 332 0.051
biological adhesion GO:0022610 21 0.050
Human Mouse Worm Fly
phosphorus metabolic process GO:0006793 232 0.050
Human Mouse
regulation of nematode larval development GO:0061062 260 0.050
regulation of developmental growth GO:0048638 389 0.049
macromolecule catabolic process GO:0009057 202 0.049
germ cell development GO:0007281 351 0.048
Fly
axon guidance GO:0007411 82 0.047
Fly
cell morphogenesis involved in differentiation GO:0000904 112 0.047
Human Zebrafish Fly
catabolic process GO:0009056 318 0.047
transcription from rna polymerase ii promoter GO:0006366 149 0.047
Mouse
integrin mediated signaling pathway GO:0007229 1 0.046
response to external stimulus GO:0009605 289 0.044
Human Fly
intracellular signal transduction GO:0035556 96 0.042
Mouse
cell migration GO:0016477 306 0.042
striated muscle contraction GO:0006941 17 0.040
regulation of anatomical structure morphogenesis GO:0022603 51 0.039
Fly
protein metabolic process GO:0019538 422 0.039
secretion by cell GO:0032940 138 0.038
regulation of apoptotic signaling pathway GO:2001233 1 0.038
Human
regulation of localization GO:0032879 194 0.038
regulation of vulval development GO:0040028 248 0.038
muscle contraction GO:0006936 43 0.038
regulation of signaling GO:0023051 172 0.037
Human Mouse
cellular biosynthetic process GO:0044249 315 0.037
Mouse
chromosome segregation GO:0007059 180 0.036
regulation of primary metabolic process GO:0080090 292 0.035
Human Mouse
protein complex assembly GO:0006461 186 0.035
programmed cell death GO:0012501 500 0.035
Human Mouse
cell part morphogenesis GO:0032990 152 0.034
Fly
vulval development GO:0040025 333 0.033
response to abiotic stimulus GO:0009628 152 0.033
oogenesis GO:0048477 229 0.033
Fly
nucleic acid metabolic process GO:0090304 299 0.032
Mouse
macromolecule modification GO:0043412 218 0.031
Human
signal transduction GO:0007165 317 0.031
cellular localization GO:0051641 360 0.031
regulation of organelle organization GO:0033043 164 0.030
Fly
regulation of biosynthetic process GO:0009889 189 0.029
Human Mouse
negative regulation of macromolecule metabolic process GO:0010605 229 0.029
Human
phagocytosis engulfment GO:0006911 98 0.029
system process GO:0003008 136 0.028
phosphate containing compound metabolic process GO:0006796 232 0.028
Human Mouse
cell cell signaling GO:0007267 118 0.028
cell substrate adhesion GO:0031589 1 0.028
Human Mouse
regulation of cell death GO:0010941 65 0.028
Human
multi organism reproductive behavior GO:0044705 387 0.027
regulation of response to stimulus GO:0048583 243 0.027
Human Mouse
sarcomere organization GO:0045214 10 0.027
regulation of programmed cell death GO:0043067 50 0.027
Human
positive regulation of cell migration GO:0030335 3 0.026
Mouse
localization of cell GO:0051674 313 0.026
response to wounding GO:0009611 4 0.025
Human Zebrafish
epithelium development GO:0060429 68 0.025
Human Zebrafish Fly
er nucleus signaling pathway GO:0006984 66 0.025
cell projection organization GO:0030030 231 0.025
Mouse Worm Fly
cell proliferation GO:0008283 116 0.025
Human Zebrafish Mouse
regulation of phagocytosis engulfment GO:0060099 17 0.025
regulation of mapk cascade GO:0043408 23 0.024
regulation of post embryonic development GO:0048580 260 0.024
single organismal cell cell adhesion GO:0016337 10 0.024
Human Mouse Worm
negative regulation of apoptotic process GO:0043066 17 0.024
Human
multicellular organism reproduction GO:0032504 819 0.023
cell recognition GO:0008037 85 0.023
Worm Fly
regulation of apoptotic process GO:0042981 36 0.023
Human
regulation of macromolecule biosynthetic process GO:0010556 189 0.023
Human Mouse
negative regulation of gene expression GO:0010629 217 0.023
regulation of phosphorylation GO:0042325 45 0.023
Human
organic substance catabolic process GO:1901575 294 0.023
cuticle development GO:0042335 100 0.023
response to topologically incorrect protein GO:0035966 82 0.022
regulation of epithelial cell proliferation GO:0050678 1 0.022
regulation of cellular component movement GO:0051270 62 0.022
Mouse
cellular response to stress GO:0033554 162 0.021
tube morphogenesis GO:0035239 79 0.021
Human Zebrafish Worm
membrane invagination GO:0010324 98 0.021
cell junction organization GO:0034330 18 0.021
Mouse
single organism membrane organization GO:0044802 35 0.021
regulation of cell cell adhesion GO:0022407 1 0.020
negative regulation of cell communication GO:0010648 61 0.020
Human
posttranscriptional regulation of gene expression GO:0010608 166 0.019
cell division GO:0051301 262 0.019
molting cycle GO:0042303 281 0.018
protein modification process GO:0036211 207 0.018
Human
regulation of system process GO:0044057 27 0.018
negative regulation of multicellular organismal process GO:0051241 236 0.018
endoplasmic reticulum unfolded protein response GO:0030968 66 0.017
negative regulation of signaling GO:0023057 61 0.017
Human
nucleobase containing compound biosynthetic process GO:0034654 184 0.017
Mouse
negative regulation of metabolic process GO:0009892 240 0.017
Human
actin filament bundle assembly GO:0051017 3 0.017
Fly
cellular amino acid metabolic process GO:0006520 15 0.017
regulation of cell motility GO:2000145 57 0.017
Mouse
epithelial tube morphogenesis GO:0060562 1 0.016
regulation of locomotion GO:0040012 161 0.016
pharyngeal pumping GO:0043050 58 0.016
negative regulation of nematode larval development GO:0061064 208 0.016
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.016
Mouse
establishment of protein localization to membrane GO:0090150 3 0.016
transcription dna templated GO:0006351 168 0.016
Mouse
neuron projection morphogenesis GO:0048812 114 0.015
Fly
positive regulation of cysteine type endopeptidase activity GO:2001056 3 0.015
collagen and cuticulin based cuticle development GO:0040002 99 0.015
positive regulation of macromolecule metabolic process GO:0010604 149 0.015
Human Mouse
cell morphogenesis GO:0000902 163 0.015
Human Zebrafish Fly
organonitrogen compound metabolic process GO:1901564 151 0.015
meiotic cell cycle process GO:1903046 170 0.015
regulation of rna biosynthetic process GO:2001141 165 0.015
Mouse
epithelial cell proliferation GO:0050673 1 0.014
Zebrafish
rna interference GO:0016246 137 0.014
neuron recognition GO:0008038 83 0.014
Worm Fly
small molecule metabolic process GO:0044281 186 0.014
establishment of localization in cell GO:0051649 318 0.014
embryonic body morphogenesis GO:0010172 49 0.014
positive regulation of hydrolase activity GO:0051345 38 0.014
oxoacid metabolic process GO:0043436 47 0.014
regulation of intracellular signal transduction GO:1902531 77 0.014
cell projection assembly GO:0030031 35 0.014
organic cyclic compound biosynthetic process GO:1901362 195 0.014
Mouse
mitotic cell cycle process GO:1903047 194 0.013
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.013
Mouse
peptidyl lysine trimethylation GO:0018023 2 0.013
cation transport GO:0006812 78 0.013
Human
protein phosphorylation GO:0006468 85 0.013
Human
regulation of cell cycle GO:0051726 194 0.013
cellular protein localization GO:0034613 75 0.013
carbohydrate derivative metabolic process GO:1901135 141 0.013
regulation of macromolecule metabolic process GO:0060255 421 0.012
Human Mouse
cellular macromolecule biosynthetic process GO:0034645 247 0.012
Mouse
defense response GO:0006952 296 0.012
negative regulation of signal transduction GO:0009968 60 0.012
Human
nucleobase containing compound metabolic process GO:0006139 406 0.012
Mouse
phosphorylation GO:0016310 116 0.012
Human Mouse
cytokinesis GO:0000910 80 0.012
regulation of molecular function GO:0065009 89 0.012
response to endogenous stimulus GO:0009719 33 0.012
Mouse
ovulation GO:0030728 33 0.012
protein localization GO:0008104 205 0.011
Mouse Fly
biosynthetic process GO:0009058 323 0.011
Human Mouse
cellular nitrogen compound biosynthetic process GO:0044271 192 0.011
Mouse
regulation of gene expression epigenetic GO:0040029 163 0.011
excretion GO:0007588 49 0.011
cellular response to topologically incorrect protein GO:0035967 76 0.011
negative regulation of response to stimulus GO:0048585 73 0.011
Human
somatic muscle development GO:0007525 1 0.010
regulation of gene silencing by rna GO:0060966 3 0.010
feeding behavior GO:0007631 70 0.010
eating behavior GO:0042755 59 0.010
regulation of anatomical structure size GO:0090066 46 0.010
cell substrate junction assembly GO:0007044 13 0.010
Mouse
signal transduction by phosphorylation GO:0023014 31 0.010
Mouse
axonal fasciculation GO:0007413 79 0.010
Worm
response to unfolded protein GO:0006986 71 0.010
nucleus localization GO:0051647 55 0.010

pat-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
myopathy DOID:423 0 0.031
muscular disease DOID:0080000 0 0.031
heart disease DOID:114 0 0.031
cardiomyopathy DOID:0050700 0 0.031
disease of anatomical entity DOID:7 0 0.031
cardiovascular system disease DOID:1287 0 0.031
musculoskeletal system disease DOID:17 0 0.031
muscle tissue disease DOID:66 0 0.031