Caenorhabditis elegans

0 known processes

best-3 (CELE_C01B12.3)

Protein BEST-3

best-3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development GO:0009790 3052 0.616
embryo development ending in birth or egg hatching GO:0009792 2992 0.512
hermaphrodite genitalia development GO:0040035 734 0.298
development of primary sexual characteristics GO:0045137 840 0.295
genitalia development GO:0048806 741 0.293
post embryonic development GO:0009791 2152 0.245
reproductive structure development GO:0048608 850 0.229
organ development GO:0048513 1102 0.211
p38mapk cascade GO:0038066 2 0.200
organelle organization GO:0006996 783 0.185
reproductive system development GO:0061458 850 0.173
gonad development GO:0008406 840 0.170
cell development GO:0048468 696 0.166
cellular localization GO:0051641 360 0.165
determination of adult lifespan GO:0008340 812 0.160
aging GO:0007568 812 0.154
meiotic nuclear division GO:0007126 300 0.154
multicellular organismal reproductive process GO:0048609 815 0.149
vesicle mediated transport GO:0016192 852 0.141
sex differentiation GO:0007548 909 0.140
establishment of localization GO:0051234 1171 0.138
macromolecule localization GO:0033036 771 0.131
developmental process involved in reproduction GO:0003006 1165 0.127
single organism reproductive process GO:0044702 1196 0.127
single organism transport GO:0044765 447 0.124
regulation of biological quality GO:0065008 741 0.122
endocytosis GO:0006897 819 0.117
regulation of developmental process GO:0050793 684 0.115
multicellular organismal aging GO:0010259 812 0.114
locomotion GO:0040011 1634 0.107
small molecule metabolic process GO:0044281 186 0.104
transport GO:0006810 1093 0.104
single organism localization GO:1902578 518 0.104
meiotic cell cycle GO:0051321 335 0.098
growth GO:0040007 562 0.097
receptor mediated endocytosis GO:0006898 715 0.096
regulation of multicellular organismal process GO:0051239 726 0.093
regulation of developmental growth GO:0048638 389 0.092
response to osmotic stress GO:0006970 29 0.087
cellular component biogenesis GO:0044085 297 0.087
multicellular organism growth GO:0035264 385 0.086
body morphogenesis GO:0010171 620 0.084
lipid localization GO:0010876 573 0.083
cell cycle process GO:0022402 482 0.081
regulation of growth GO:0040008 409 0.077
regulation of multicellular organism growth GO:0040014 373 0.072
maintenance of location GO:0051235 580 0.071
response to other organism GO:0051707 101 0.070
lipid storage GO:0019915 565 0.069
regulation of metabolic process GO:0019222 478 0.068
gamete generation GO:0007276 461 0.066
oxoacid metabolic process GO:0043436 47 0.065
nucleic acid metabolic process GO:0090304 299 0.063
defense response to other organism GO:0098542 100 0.060
positive regulation of growth GO:0045927 369 0.060
negative regulation of biological process GO:0048519 567 0.058
organelle assembly GO:0070925 214 0.057
death GO:0016265 547 0.055
developmental growth GO:0048589 412 0.055
protein catabolic process GO:0030163 162 0.053
cytoskeleton organization GO:0007010 339 0.053
response to external stimulus GO:0009605 289 0.052
ion transport GO:0006811 113 0.052
multi organism reproductive process GO:0044703 867 0.050
cellular nitrogen compound biosynthetic process GO:0044271 192 0.050
response to abiotic stimulus GO:0009628 152 0.050
striated muscle cell differentiation GO:0051146 158 0.049
cell death GO:0008219 547 0.049
response to biotic stimulus GO:0009607 101 0.048
defense response to gram negative bacterium GO:0050829 64 0.048
defense response to bacterium GO:0042742 86 0.047
establishment of organelle localization GO:0051656 123 0.047
rna metabolic process GO:0016070 228 0.046
positive regulation of multicellular organism growth GO:0040018 352 0.046
nucleobase containing compound metabolic process GO:0006139 406 0.045
regulation of neurotransmitter levels GO:0001505 36 0.045
oviposition GO:0018991 364 0.045
multicellular organism reproduction GO:0032504 819 0.044
gene expression GO:0010467 412 0.044
regulation of localization GO:0032879 194 0.044
single organism organelle organization GO:1902589 501 0.042
positive regulation of developmental growth GO:0048639 354 0.042
protein localization GO:0008104 205 0.042
neurotransmitter metabolic process GO:0042133 6 0.041
actin cytoskeleton organization GO:0030036 184 0.040
regulation of nitrogen compound metabolic process GO:0051171 222 0.040
sexual reproduction GO:0019953 546 0.040
multi organism reproductive behavior GO:0044705 387 0.040
cellular component assembly involved in morphogenesis GO:0010927 183 0.039
actomyosin structure organization GO:0031032 154 0.039
transmembrane transport GO:0055085 110 0.038
defense response GO:0006952 296 0.038
reproductive behavior GO:0019098 387 0.038
cellular component assembly GO:0022607 293 0.038
regulation of cellular component organization GO:0051128 248 0.038
positive regulation of multicellular organismal process GO:0051240 417 0.037
positive regulation of developmental process GO:0051094 408 0.037
cellular protein complex assembly GO:0043623 178 0.037
response to chemical GO:0042221 356 0.036
protein complex subunit organization GO:0071822 280 0.036
organic substance transport GO:0071702 113 0.035
phosphorus metabolic process GO:0006793 232 0.034
protein metabolic process GO:0019538 422 0.034
head development GO:0060322 1 0.033
organonitrogen compound metabolic process GO:1901564 151 0.033
organelle fission GO:0048285 363 0.033
positive regulation of cellular process GO:0048522 332 0.032
multi organism behavior GO:0051705 389 0.032
multi multicellular organism process GO:0044706 390 0.032
organic cyclic compound biosynthetic process GO:1901362 195 0.032
nervous system development GO:0007399 253 0.032
striated muscle cell development GO:0055002 157 0.032
organic substance catabolic process GO:1901575 294 0.031
tissue development GO:0009888 112 0.031
germ cell development GO:0007281 351 0.031
nucleotide metabolic process GO:0009117 108 0.031
regulation of gene expression epigenetic GO:0040029 163 0.031
negative regulation of metabolic process GO:0009892 240 0.030
cell cycle GO:0007049 526 0.030
small molecule biosynthetic process GO:0044283 38 0.029
organonitrogen compound biosynthetic process GO:1901566 44 0.029
response to bacterium GO:0009617 86 0.029
single organism cellular localization GO:1902580 72 0.029
aromatic compound biosynthetic process GO:0019438 192 0.029
negative regulation of cellular process GO:0048523 239 0.028
programmed cell death GO:0012501 500 0.028
cellular response to abiotic stimulus GO:0071214 4 0.028
carboxylic acid metabolic process GO:0019752 34 0.028
cellular component movement GO:0006928 388 0.028
establishment of localization in cell GO:0051649 318 0.028
cellular amine metabolic process GO:0044106 15 0.028
cell division GO:0051301 262 0.027
secretion GO:0046903 147 0.027
posttranscriptional gene silencing GO:0016441 143 0.027
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.027
muscle cell differentiation GO:0042692 171 0.027
regulation of primary metabolic process GO:0080090 292 0.027
regulation of ion transport GO:0043269 39 0.026
phosphorylation GO:0016310 116 0.026
hyperosmotic response GO:0006972 19 0.026
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.026
actin filament based process GO:0030029 191 0.026
cellular macromolecular complex assembly GO:0034622 184 0.025
female gamete generation GO:0007292 254 0.025
macromolecular complex subunit organization GO:0043933 320 0.025
cell cell signaling GO:0007267 118 0.025
muscle structure development GO:0061061 191 0.025
response to heat GO:0009408 50 0.025
behavior GO:0007610 527 0.024
regulation of bmp signaling pathway GO:0030510 3 0.024
regulation of macromolecule metabolic process GO:0060255 421 0.024
muscle cell development GO:0055001 158 0.024
cellular catabolic process GO:0044248 199 0.024
immune response GO:0006955 192 0.023
chemosensory behavior GO:0007635 33 0.023
regulation of cell communication GO:0010646 176 0.023
macromolecule catabolic process GO:0009057 202 0.023
striated muscle myosin thick filament assembly GO:0071688 138 0.022
eating behavior GO:0042755 59 0.022
regulation of striated muscle contraction GO:0006942 4 0.022
heterocycle biosynthetic process GO:0018130 187 0.022
myosin filament assembly GO:0031034 138 0.022
cellular response to metal ion GO:0071248 3 0.022
regulation of multi organism process GO:0043900 69 0.022
negative regulation of vulval development GO:0040027 206 0.022
anatomical structure formation involved in morphogenesis GO:0048646 250 0.022
cation transport GO:0006812 78 0.022
cellular component morphogenesis GO:0032989 318 0.022
vulval development GO:0040025 333 0.021
gene silencing GO:0016458 143 0.021
negative regulation of gene expression GO:0010629 217 0.021
phosphate containing compound metabolic process GO:0006796 232 0.021
response to temperature stimulus GO:0009266 66 0.021
mitotic cell cycle process GO:1903047 194 0.021
regulation of transport GO:0051049 91 0.021
regulation of cellular ketone metabolic process GO:0010565 3 0.021
system process GO:0003008 136 0.020
organelle localization GO:0051640 127 0.020
neurogenesis GO:0022008 236 0.020
regulation of cellular metabolic process GO:0031323 305 0.020
regulation of cellular biosynthetic process GO:0031326 189 0.020
actin filament based movement GO:0030048 4 0.020
regulation of oviposition GO:0046662 43 0.020
myofibril assembly GO:0030239 154 0.020
single organism biosynthetic process GO:0044711 91 0.019
posttranscriptional gene silencing by rna GO:0035194 143 0.019
multicellular organismal reproductive behavior GO:0033057 384 0.019
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.019
myosin filament organization GO:0031033 138 0.019
negative regulation of developmental process GO:0051093 227 0.019
regulation of rna biosynthetic process GO:2001141 165 0.019
protein complex biogenesis GO:0070271 186 0.018
establishment of vesicle localization GO:0051650 23 0.018
macromolecule modification GO:0043412 218 0.018
macromolecular complex assembly GO:0065003 193 0.018
pharyngeal pumping GO:0043050 58 0.018
peptide metabolic process GO:0006518 7 0.018
protein phosphorylation GO:0006468 85 0.018
apoptotic process GO:0006915 478 0.018
neuron projection development GO:0031175 187 0.018
localization of cell GO:0051674 313 0.018
cellular protein modification process GO:0006464 207 0.018
cellular protein metabolic process GO:0044267 279 0.018
regulation of nucleic acid templated transcription GO:1903506 165 0.018
generation of neurons GO:0048699 235 0.018
gene silencing by rna GO:0031047 143 0.017
positive regulation of striated muscle contraction GO:0045989 2 0.017
regulation of multicellular organismal development GO:2000026 317 0.017
positive regulation of transcription from rna polymerase ii promoter involved in defense response to gram negative bacterium GO:1902097 4 0.017
defense response to fungus GO:0050832 19 0.017
response to mechanical stimulus GO:0009612 28 0.017
neurotransmitter catabolic process GO:0042135 4 0.017
regulation of organelle organization GO:0033043 164 0.017
rna biosynthetic process GO:0032774 169 0.017
peptidyl serine modification GO:0018209 20 0.016
regulation of cellular amine metabolic process GO:0033238 0 0.016
protein complex assembly GO:0006461 186 0.016
biosynthetic process GO:0009058 323 0.016
regulation of lipid transport GO:0032368 4 0.016
regulation of muscle system process GO:0090257 20 0.016
catabolic process GO:0009056 318 0.016
rna interference GO:0016246 137 0.016
regulation of cytoplasmic transport GO:1903649 3 0.016
organic substance biosynthetic process GO:1901576 323 0.016
secretion by cell GO:0032940 138 0.016
protein modification process GO:0036211 207 0.016
regulation of rna metabolic process GO:0051252 173 0.016
response to external biotic stimulus GO:0043207 101 0.016
glycosyl compound metabolic process GO:1901657 100 0.016
anion transport GO:0006820 30 0.015
organic acid metabolic process GO:0006082 47 0.015
regulation of gene expression GO:0010468 366 0.015
muscle organ morphogenesis GO:0048644 4 0.015
acetylcholine metabolic process GO:0008291 4 0.015
response to nutrient levels GO:0031667 35 0.015
nucleoside phosphate metabolic process GO:0006753 108 0.015
response to wounding GO:0009611 4 0.015
post embryonic organ development GO:0048569 336 0.015
peptidyl serine phosphorylation GO:0018105 20 0.015
cellular macromolecule localization GO:0070727 75 0.015
nucleobase containing small molecule metabolic process GO:0055086 115 0.015
nucleoside catabolic process GO:0009164 78 0.015
cellular biosynthetic process GO:0044249 315 0.015
negative regulation of nematode larval development GO:0061064 208 0.015
regulation of apoptotic signaling pathway GO:2001233 1 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.014
regulation of feeding behavior GO:0060259 38 0.014
ion transmembrane transport GO:0034220 91 0.014
positive regulation of transcription from rna polymerase ii promoter in response to osmotic stress GO:0061393 1 0.014
cell migration GO:0016477 306 0.014
dauer larval development GO:0040024 92 0.014
regulation of nematode larval development GO:0061062 260 0.014
lipid biosynthetic process GO:0008610 28 0.014
regulation of reproductive process GO:2000241 66 0.014
peptidyl amino acid modification GO:0018193 58 0.013
regulation of signaling GO:0023051 172 0.013
posttranscriptional regulation of gene expression GO:0010608 166 0.013
regulation of muscle contraction GO:0006937 20 0.013
amine metabolic process GO:0009308 15 0.013
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.013
nucleobase containing compound biosynthetic process GO:0034654 184 0.013
molting cycle GO:0042303 281 0.013
sensory perception of taste GO:0050909 4 0.013
transcription dna templated GO:0006351 168 0.013
nucleobase containing compound catabolic process GO:0034655 114 0.013
oogenesis GO:0048477 229 0.013
synaptic transmission GO:0007268 106 0.013
cell type specific apoptotic process GO:0097285 4 0.013
organophosphate metabolic process GO:0019637 125 0.013
tube development GO:0035295 126 0.012
acetate ester metabolic process GO:1900619 4 0.012
organonitrogen compound catabolic process GO:1901565 90 0.012
apoptotic cell clearance GO:0043277 111 0.012
epithelial tube morphogenesis GO:0060562 1 0.012
regulation of cellular amino acid metabolic process GO:0006521 0 0.012
regulation of biosynthetic process GO:0009889 189 0.012
regulation of lipid biosynthetic process GO:0046890 1 0.012
negative regulation of multicellular organismal process GO:0051241 236 0.012
cellular protein localization GO:0034613 75 0.012
establishment or maintenance of cell polarity GO:0007163 63 0.012
negative regulation of post embryonic development GO:0048581 208 0.012
negative regulation of macromolecule metabolic process GO:0010605 229 0.012
epithelium development GO:0060429 68 0.011
ribonucleoside triphosphate metabolic process GO:0009199 87 0.011
regulation of cell cycle process GO:0010564 145 0.011
cytokinesis GO:0000910 80 0.011
regulation of transcription dna templated GO:0006355 164 0.011
epithelial cell proliferation GO:0050673 1 0.011
positive regulation of protein transport GO:0051222 4 0.011
regulation of vulval development GO:0040028 248 0.011
regulation of protein localization GO:0032880 50 0.011
positive regulation of immune response GO:0050778 7 0.011
purine nucleoside metabolic process GO:0042278 92 0.011
regulation of protein targeting GO:1903533 3 0.011
regulation of lipid metabolic process GO:0019216 4 0.011
cell recognition GO:0008037 85 0.011
single organism catabolic process GO:0044712 129 0.011
regulation of protein stability GO:0031647 3 0.011
cellular response to stress GO:0033554 162 0.011
regulation of system process GO:0044057 27 0.011
cell projection organization GO:0030030 231 0.011
lamellipodium assembly GO:0030032 2 0.011
regulation of macromolecule biosynthetic process GO:0010556 189 0.010
positive regulation of synaptic transmission GO:0050806 24 0.010
cellular amino acid metabolic process GO:0006520 15 0.010
cellular ketone metabolic process GO:0042180 14 0.010
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.010
protein localization to organelle GO:0033365 37 0.010
signaling GO:0023052 401 0.010
rna localization GO:0006403 3 0.010
response to extracellular stimulus GO:0009991 38 0.010
macromolecule biosynthetic process GO:0009059 250 0.010
bmp signaling pathway GO:0030509 3 0.010
cellular nitrogen compound catabolic process GO:0044270 119 0.010
purine nucleoside triphosphate metabolic process GO:0009144 87 0.010
backward locomotion GO:0043057 11 0.010
regulation of locomotion GO:0040012 161 0.010
positive regulation of intracellular transport GO:0032388 2 0.010
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.010
cellular macromolecule biosynthetic process GO:0034645 247 0.010

best-3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.033
heart disease DOID:114 0 0.023
cardiovascular system disease DOID:1287 0 0.023
nervous system disease DOID:863 0 0.015
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011
organ system cancer DOID:0050686 0 0.011