Caenorhabditis elegans

24 known processes

nrde-4 (CELE_F45E4.10)

Protein NRDE-4

nrde-4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development ending in birth or egg hatching GO:0009792 2992 0.697
embryo development GO:0009790 3052 0.687
meiotic nuclear division GO:0007126 300 0.521
multi organism reproductive process GO:0044703 867 0.509
cell cycle process GO:0022402 482 0.393
multicellular organismal reproductive process GO:0048609 815 0.379
multicellular organism reproduction GO:0032504 819 0.305
sexual reproduction GO:0019953 546 0.289
cell cycle GO:0007049 526 0.257
organelle fission GO:0048285 363 0.253
organelle organization GO:0006996 783 0.231
transcription from rna polymerase ii promoter GO:0006366 149 0.218
post embryonic development GO:0009791 2152 0.211
regulation of macromolecule metabolic process GO:0060255 421 0.198
meiotic cell cycle GO:0051321 335 0.169
single organism organelle organization GO:1902589 501 0.163
death GO:0016265 547 0.158
germ cell development GO:0007281 351 0.145
single organism reproductive process GO:0044702 1196 0.136
mitotic cell cycle process GO:1903047 194 0.135
cell division GO:0051301 262 0.135
multi organism reproductive behavior GO:0044705 387 0.111
apoptotic process GO:0006915 478 0.110
response to external biotic stimulus GO:0043207 101 0.104
regulation of gene expression GO:0010468 366 0.102
establishment of localization GO:0051234 1171 0.098
programmed cell death GO:0012501 500 0.097
cell death GO:0008219 547 0.095
regulation of developmental process GO:0050793 684 0.095
oviposition GO:0018991 364 0.094
regulation of cell division GO:0051302 142 0.091
organ development GO:0048513 1102 0.091
regulation of metabolic process GO:0019222 478 0.090
multi multicellular organism process GO:0044706 390 0.089
endocytosis GO:0006897 819 0.087
cell development GO:0048468 696 0.086
macromolecular complex assembly GO:0065003 193 0.086
regulation of cell differentiation GO:0045595 81 0.084
multi organism behavior GO:0051705 389 0.083
rna metabolic process GO:0016070 228 0.080
transport GO:0006810 1093 0.079
meiotic chromosome segregation GO:0045132 139 0.078
gamete generation GO:0007276 461 0.077
multicellular organismal reproductive behavior GO:0033057 384 0.076
macromolecule catabolic process GO:0009057 202 0.074
reproductive behavior GO:0019098 387 0.073
locomotion GO:0040011 1634 0.070
gene expression GO:0010467 412 0.069
vesicle mediated transport GO:0016192 852 0.067
lipid localization GO:0010876 573 0.066
nucleic acid templated transcription GO:0097659 169 0.065
maintenance of location GO:0051235 580 0.062
lipid storage GO:0019915 565 0.059
organic substance biosynthetic process GO:1901576 323 0.058
chromosome segregation GO:0007059 180 0.058
meiotic cell cycle process GO:1903046 170 0.058
macromolecule localization GO:0033036 771 0.058
regulation of multicellular organism growth GO:0040014 373 0.058
protein modification process GO:0036211 207 0.056
gene silencing by rna GO:0031047 143 0.054
catabolic process GO:0009056 318 0.053
head development GO:0060322 1 0.052
developmental growth GO:0048589 412 0.052
regulation of nuclear division GO:0051783 115 0.052
posttranscriptional gene silencing GO:0016441 143 0.052
hermaphrodite genitalia development GO:0040035 734 0.050
protein complex assembly GO:0006461 186 0.050
cellular macromolecular complex assembly GO:0034622 184 0.050
regulation of multicellular organismal process GO:0051239 726 0.049
regulation of biological quality GO:0065008 741 0.049
behavior GO:0007610 527 0.048
reproductive structure development GO:0048608 850 0.048
nucleobase containing compound metabolic process GO:0006139 406 0.047
negative regulation of metabolic process GO:0009892 240 0.047
developmental process involved in reproduction GO:0003006 1165 0.046
regulation of growth GO:0040008 409 0.044
pole plasm assembly GO:0007315 2 0.041
single organism transport GO:0044765 447 0.041
molting cycle GO:0042303 281 0.041
sex differentiation GO:0007548 909 0.040
response to other organism GO:0051707 101 0.040
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.039
response to bacterium GO:0009617 86 0.039
response to external stimulus GO:0009605 289 0.039
aging GO:0007568 812 0.038
multicellular organism growth GO:0035264 385 0.038
positive regulation of developmental process GO:0051094 408 0.037
negative regulation of biological process GO:0048519 567 0.037
anatomical structure formation involved in morphogenesis GO:0048646 250 0.037
response to chemical GO:0042221 356 0.037
cytoskeleton organization GO:0007010 339 0.036
cellular component biogenesis GO:0044085 297 0.036
regulation of cellular metabolic process GO:0031323 305 0.036
post embryonic organ development GO:0048569 336 0.036
positive regulation of multicellular organism growth GO:0040018 352 0.035
nucleic acid metabolic process GO:0090304 299 0.035
regulation of nucleocytoplasmic transport GO:0046822 3 0.035
regulation of cytoplasmic transport GO:1903649 3 0.035
organelle assembly GO:0070925 214 0.034
regulation of nucleic acid templated transcription GO:1903506 165 0.034
negative regulation of gene expression GO:0010629 217 0.034
regulation of cell proliferation GO:0042127 105 0.033
cell proliferation GO:0008283 116 0.033
response to biotic stimulus GO:0009607 101 0.033
positive regulation of growth GO:0045927 369 0.032
heterocycle biosynthetic process GO:0018130 187 0.032
positive regulation of metabolic process GO:0009893 187 0.032
rna splicing GO:0008380 8 0.031
rna localization GO:0006403 3 0.031
rna biosynthetic process GO:0032774 169 0.031
negative regulation of developmental process GO:0051093 227 0.030
cellular macromolecule localization GO:0070727 75 0.030
aromatic compound biosynthetic process GO:0019438 192 0.030
positive regulation of multicellular organismal process GO:0051240 417 0.030
regulation of cell cycle process GO:0010564 145 0.030
actomyosin structure organization GO:0031032 154 0.030
striated muscle cell differentiation GO:0051146 158 0.029
positive regulation of developmental growth GO:0048639 354 0.029
positive regulation of intracellular transport GO:0032388 2 0.029
reproductive system development GO:0061458 850 0.029
cellular component assembly involved in morphogenesis GO:0010927 183 0.029
protein complex biogenesis GO:0070271 186 0.028
muscle cell development GO:0055001 158 0.028
cellular catabolic process GO:0044248 199 0.028
striated muscle myosin thick filament assembly GO:0071688 138 0.027
myosin filament organization GO:0031033 138 0.027
protein metabolic process GO:0019538 422 0.027
cellular nitrogen compound biosynthetic process GO:0044271 192 0.026
regulation of cell communication GO:0010646 176 0.026
regulation of primary metabolic process GO:0080090 292 0.026
mrna metabolic process GO:0016071 31 0.026
cellular macromolecule biosynthetic process GO:0034645 247 0.026
protein localization GO:0008104 205 0.026
protein complex subunit organization GO:0071822 280 0.026
determination of adult lifespan GO:0008340 812 0.026
meiotic chromosome separation GO:0051307 5 0.026
cellular component movement GO:0006928 388 0.025
cellular macromolecule catabolic process GO:0044265 73 0.025
chromosome condensation GO:0030261 6 0.025
regulation of organelle organization GO:0033043 164 0.025
organic substance catabolic process GO:1901575 294 0.025
cellular component assembly GO:0022607 293 0.024
transcription dna templated GO:0006351 168 0.024
myosin filament assembly GO:0031034 138 0.024
vulval development GO:0040025 333 0.023
biosynthetic process GO:0009058 323 0.023
striated muscle cell development GO:0055002 157 0.023
neuron differentiation GO:0030182 217 0.023
multicellular organismal aging GO:0010259 812 0.023
regulation of cell cycle GO:0051726 194 0.023
regulation of signaling GO:0023051 172 0.023
cellular response to dna damage stimulus GO:0006974 41 0.022
defense response to bacterium GO:0042742 86 0.022
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.022
regulation of transport GO:0051049 91 0.022
cellular protein metabolic process GO:0044267 279 0.022
regulation of gene expression epigenetic GO:0040029 163 0.022
genitalia development GO:0048806 741 0.022
regulation of meiosis GO:0040020 94 0.022
macromolecular complex subunit organization GO:0043933 320 0.022
negative regulation of nematode larval development GO:0061064 208 0.021
cellular protein localization GO:0034613 75 0.021
myofibril assembly GO:0030239 154 0.021
oogenesis GO:0048477 229 0.021
growth GO:0040007 562 0.021
organonitrogen compound metabolic process GO:1901564 151 0.021
dna metabolic process GO:0006259 74 0.020
muscle structure development GO:0061061 191 0.020
single organism signaling GO:0044700 401 0.020
macromolecule biosynthetic process GO:0009059 250 0.020
actin cytoskeleton organization GO:0030036 184 0.020
organic substance transport GO:0071702 113 0.020
cell motility GO:0048870 313 0.020
regulation of macromolecule biosynthetic process GO:0010556 189 0.020
rna interference GO:0016246 137 0.019
carbohydrate derivative metabolic process GO:1901135 141 0.019
carboxylic acid metabolic process GO:0019752 34 0.019
positive regulation of cellular metabolic process GO:0031325 178 0.019
development of primary sexual characteristics GO:0045137 840 0.019
regulation of cellular amine metabolic process GO:0033238 0 0.019
negative regulation of rna biosynthetic process GO:1902679 53 0.019
posttranscriptional gene silencing by rna GO:0035194 143 0.019
regulation of nitrogen compound metabolic process GO:0051171 222 0.019
nitrogen compound transport GO:0071705 49 0.019
regulation of protein targeting GO:1903533 3 0.019
positive regulation of macromolecule metabolic process GO:0010604 149 0.019
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.019
actin filament based process GO:0030029 191 0.019
defense response to other organism GO:0098542 100 0.018
macromolecule modification GO:0043412 218 0.018
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.018
regulation of response to stimulus GO:0048583 243 0.018
female gamete generation GO:0007292 254 0.018
nucleobase containing compound biosynthetic process GO:0034654 184 0.017
muscle cell differentiation GO:0042692 171 0.017
cellular protein modification process GO:0006464 207 0.017
regulation of rna biosynthetic process GO:2001141 165 0.017
defense response GO:0006952 296 0.017
organ morphogenesis GO:0009887 67 0.017
mitotic g2 m transition checkpoint GO:0044818 1 0.017
gene silencing GO:0016458 143 0.017
receptor mediated endocytosis GO:0006898 715 0.016
protein catabolic process GO:0030163 162 0.016
negative regulation of post embryonic development GO:0048581 208 0.016
localization of cell GO:0051674 313 0.016
positive regulation of cellular process GO:0048522 332 0.016
spindle organization GO:0007051 92 0.016
regulation of localization GO:0032879 194 0.016
regulation of lipid biosynthetic process GO:0046890 1 0.016
nucleobase containing small molecule metabolic process GO:0055086 115 0.016
cellular protein complex assembly GO:0043623 178 0.016
oocyte construction GO:0007308 2 0.016
organic cyclic compound biosynthetic process GO:1901362 195 0.016
cellular nitrogen compound catabolic process GO:0044270 119 0.015
immune response GO:0006955 192 0.015
regulation of protein import into nucleus GO:0042306 3 0.015
cell migration GO:0016477 306 0.015
intracellular receptor signaling pathway GO:0030522 2 0.015
regulation of biosynthetic process GO:0009889 189 0.015
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.015
hermaphrodite germ line sex determination GO:0040021 48 0.015
metaphase anaphase transition of mitotic cell cycle GO:0007091 10 0.015
germ line sex determination GO:0018992 51 0.014
nervous system development GO:0007399 253 0.014
cellular response to organic substance GO:0071310 119 0.014
negative regulation of multicellular organismal process GO:0051241 236 0.014
organic acid metabolic process GO:0006082 47 0.014
oocyte axis specification GO:0007309 2 0.013
cellular response to stress GO:0033554 162 0.013
establishment of localization in cell GO:0051649 318 0.013
negative regulation of transcription from rna polymerase ii promoter GO:0000122 45 0.013
male sex differentiation GO:0046661 86 0.013
cellular component morphogenesis GO:0032989 318 0.013
regulation of cellular ketone metabolic process GO:0010565 3 0.013
regulation of cellular component organization GO:0051128 248 0.013
regulation of developmental growth GO:0048638 389 0.013
lipid metabolic process GO:0006629 77 0.013
regulation of meiotic cell cycle GO:0051445 136 0.012
sex determination GO:0007530 60 0.012
posttranscriptional regulation of gene expression GO:0010608 166 0.012
body morphogenesis GO:0010171 620 0.012
organophosphate metabolic process GO:0019637 125 0.012
tube development GO:0035295 126 0.012
secretion GO:0046903 147 0.012
regulation of mitotic cell cycle GO:0007346 76 0.012
embryonic morphogenesis GO:0048598 152 0.012
mitotic sister chromatid segregation GO:0000070 38 0.011
epithelial tube morphogenesis GO:0060562 1 0.011
negative regulation of macromolecule metabolic process GO:0010605 229 0.011
regulation of post embryonic development GO:0048580 260 0.011
mitotic spindle organization GO:0007052 81 0.011
regulation of cellular amino acid metabolic process GO:0006521 0 0.011
internal peptidyl lysine acetylation GO:0018393 3 0.011
digestive system development GO:0055123 122 0.011
microtubule polymerization or depolymerization GO:0031109 22 0.011
negative regulation of vulval development GO:0040027 206 0.011
regulation of cellular biosynthetic process GO:0031326 189 0.011
regulation of transcription dna templated GO:0006355 164 0.010
regulation of sister chromatid segregation GO:0033045 16 0.010
cellular localization GO:0051641 360 0.010
nuclear transcribed mrna catabolic process nonsense mediated decay GO:0000184 9 0.010
meiosis i GO:0007127 19 0.010
chromosome organization GO:0051276 104 0.010
single organism localization GO:1902578 518 0.010
negative regulation of transcription dna templated GO:0045892 53 0.010
response to organic substance GO:0010033 131 0.010

nrde-4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
spinocerebellar degeneration DOID:2478 0 0.014
central nervous system disease DOID:331 0 0.014
disease of anatomical entity DOID:7 0 0.014
neurodegenerative disease DOID:1289 0 0.014
nervous system disease DOID:863 0 0.014