Caenorhabditis elegans

85 known processes

unc-75 (CELE_C17D12.2)

Protein UNC-75

unc-75 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development GO:0009790 3052 0.277
Worm
locomotion GO:0040011 1634 0.212
Mouse Worm
embryo development ending in birth or egg hatching GO:0009792 2992 0.195
Worm
regulation of developmental process GO:0050793 684 0.188
regulation of multicellular organismal process GO:0051239 726 0.158
regulation of biological quality GO:0065008 741 0.138
Mouse
post embryonic development GO:0009791 2152 0.132
Worm
developmental process involved in reproduction GO:0003006 1165 0.128
Worm
establishment of localization GO:0051234 1171 0.118
positive regulation of developmental process GO:0051094 408 0.114
regulation of metabolic process GO:0019222 478 0.112
receptor mediated endocytosis GO:0006898 715 0.111
cell development GO:0048468 696 0.109
transport GO:0006810 1093 0.108
germ cell development GO:0007281 351 0.107
Worm
nucleic acid metabolic process GO:0090304 299 0.107
regulation of gene expression GO:0010468 366 0.104
behavior GO:0007610 527 0.102
Worm
multicellular organismal reproductive process GO:0048609 815 0.098
Mouse Worm
cell death GO:0008219 547 0.096
Worm
apoptotic process GO:0006915 478 0.095
Worm
sexual reproduction GO:0019953 546 0.095
Mouse Worm
multicellular organism growth GO:0035264 385 0.095
organ development GO:0048513 1102 0.092
growth GO:0040007 562 0.092
cell cycle GO:0007049 526 0.090
vesicle mediated transport GO:0016192 852 0.089
multi organism reproductive process GO:0044703 867 0.089
Mouse Worm
single organism signaling GO:0044700 401 0.088
cytoskeleton organization GO:0007010 339 0.087
single organism reproductive process GO:0044702 1196 0.087
Mouse Worm
death GO:0016265 547 0.084
Worm
positive regulation of multicellular organismal process GO:0051240 417 0.082
macromolecule localization GO:0033036 771 0.080
organelle organization GO:0006996 783 0.079
positive regulation of growth GO:0045927 369 0.075
regulation of multicellular organismal development GO:2000026 317 0.074
aging GO:0007568 812 0.074
Worm
reproductive behavior GO:0019098 387 0.073
Worm
positive regulation of metabolic process GO:0009893 187 0.073
rna metabolic process GO:0016070 228 0.072
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.070
Worm
regulation of developmental growth GO:0048638 389 0.070
multicellular organismal aging GO:0010259 812 0.070
Worm
gene expression GO:0010467 412 0.069
reproductive system development GO:0061458 850 0.069
lipid localization GO:0010876 573 0.068
maintenance of location GO:0051235 580 0.067
female gamete generation GO:0007292 254 0.067
Worm
cellular macromolecule biosynthetic process GO:0034645 247 0.067
multicellular organism reproduction GO:0032504 819 0.066
Mouse Worm
cellular component morphogenesis GO:0032989 318 0.065
oogenesis GO:0048477 229 0.065
Worm
positive regulation of cellular process GO:0048522 332 0.065
protein metabolic process GO:0019538 422 0.064
establishment of localization in cell GO:0051649 318 0.064
determination of adult lifespan GO:0008340 812 0.064
Worm
lipid storage GO:0019915 565 0.064
cellular biosynthetic process GO:0044249 315 0.064
gonad development GO:0008406 840 0.063
oviposition GO:0018991 364 0.063
Worm
multi multicellular organism process GO:0044706 390 0.062
Worm
positive regulation of multicellular organism growth GO:0040018 352 0.061
negative regulation of cellular process GO:0048523 239 0.061
Mouse
development of primary sexual characteristics GO:0045137 840 0.060
developmental growth GO:0048589 412 0.060
reproductive structure development GO:0048608 850 0.060
nucleobase containing compound metabolic process GO:0006139 406 0.060
cellular component movement GO:0006928 388 0.059
Mouse
anatomical structure formation involved in morphogenesis GO:0048646 250 0.059
regulation of growth GO:0040008 409 0.059
generation of neurons GO:0048699 235 0.059
regulation of multicellular organism growth GO:0040014 373 0.058
cell cycle process GO:0022402 482 0.058
single organism organelle organization GO:1902589 501 0.057
multi organism behavior GO:0051705 389 0.056
Worm
hermaphrodite genitalia development GO:0040035 734 0.056
regulation of cellular component organization GO:0051128 248 0.056
localization of cell GO:0051674 313 0.055
Mouse
post embryonic organ development GO:0048569 336 0.055
sex differentiation GO:0007548 909 0.055
regulation of cellular biosynthetic process GO:0031326 189 0.055
negative regulation of multicellular organismal process GO:0051241 236 0.054
single organism localization GO:1902578 518 0.054
protein complex subunit organization GO:0071822 280 0.053
gamete generation GO:0007276 461 0.053
Mouse Worm
organic substance biosynthetic process GO:1901576 323 0.052
endocytosis GO:0006897 819 0.052
regulation of primary metabolic process GO:0080090 292 0.050
cellular localization GO:0051641 360 0.050
cellular component biogenesis GO:0044085 297 0.050
Mouse
positive regulation of developmental growth GO:0048639 354 0.049
positive regulation of gene expression GO:0010628 112 0.048
cell migration GO:0016477 306 0.047
organelle fission GO:0048285 363 0.047
regulation of cellular metabolic process GO:0031323 305 0.046
actin filament based process GO:0030029 191 0.046
negative regulation of biological process GO:0048519 567 0.046
Mouse
negative regulation of metabolic process GO:0009892 240 0.045
Mouse
regulation of macromolecule metabolic process GO:0060255 421 0.044
response to chemical GO:0042221 356 0.044
macromolecule biosynthetic process GO:0009059 250 0.044
biosynthetic process GO:0009058 323 0.044
negative regulation of developmental process GO:0051093 227 0.044
body morphogenesis GO:0010171 620 0.044
Worm
regulation of rna metabolic process GO:0051252 173 0.043
single organism transport GO:0044765 447 0.043
positive regulation of macromolecule metabolic process GO:0010604 149 0.042
response to wounding GO:0009611 4 0.042
signal transduction GO:0007165 317 0.042
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.041
mitotic cell cycle process GO:1903047 194 0.041
neuron development GO:0048666 199 0.041
multi organism reproductive behavior GO:0044705 387 0.041
Worm
programmed cell death GO:0012501 500 0.041
Worm
signaling GO:0023052 401 0.041
regulation of macromolecule biosynthetic process GO:0010556 189 0.040
positive regulation of biosynthetic process GO:0009891 109 0.040
system process GO:0003008 136 0.040
Worm
negative regulation of gene expression GO:0010629 217 0.040
Mouse
cell division GO:0051301 262 0.040
neuron projection development GO:0031175 187 0.039
cellular protein metabolic process GO:0044267 279 0.039
neurogenesis GO:0022008 236 0.039
regulation of vulval development GO:0040028 248 0.038
cell motility GO:0048870 313 0.037
Mouse
nervous system development GO:0007399 253 0.037
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.036
positive regulation of cellular metabolic process GO:0031325 178 0.036
cellular component assembly GO:0022607 293 0.036
Mouse
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.036
genitalia development GO:0048806 741 0.036
regulation of stem cell differentiation GO:2000736 1 0.036
single organism behavior GO:0044708 83 0.036
regulation of nitrogen compound metabolic process GO:0051171 222 0.035
negative regulation of macromolecule metabolic process GO:0010605 229 0.034
Mouse
multicellular organismal reproductive behavior GO:0033057 384 0.034
Worm
organelle assembly GO:0070925 214 0.034
neuron projection morphogenesis GO:0048812 114 0.033
secretion by cell GO:0032940 138 0.033
head development GO:0060322 1 0.033
macromolecular complex subunit organization GO:0043933 320 0.033
Mouse
regulation of nematode larval development GO:0061062 260 0.032
cell surface receptor signaling pathway GO:0007166 149 0.032
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.032
embryonic morphogenesis GO:0048598 152 0.032
Worm
regulation of cell division GO:0051302 142 0.031
vulval development GO:0040025 333 0.031
actin cytoskeleton organization GO:0030036 184 0.031
positive regulation of cellular biosynthetic process GO:0031328 109 0.031
meiotic cell cycle GO:0051321 335 0.031
cell projection organization GO:0030030 231 0.031
meiotic nuclear division GO:0007126 300 0.031
negative regulation of post embryonic development GO:0048581 208 0.030
memory GO:0007613 3 0.030
cellular macromolecular complex assembly GO:0034622 184 0.030
Mouse
neuron differentiation GO:0030182 217 0.030
positive regulation of neuron differentiation GO:0045666 4 0.030
cell projection morphogenesis GO:0048858 148 0.029
actomyosin structure organization GO:0031032 154 0.029
regulation of biosynthetic process GO:0009889 189 0.029
cell morphogenesis GO:0000902 163 0.029
negative regulation of vulval development GO:0040027 206 0.029
inductive cell migration GO:0040039 145 0.029
cognition GO:0050890 27 0.028
skeletal muscle organ development GO:0060538 3 0.028
myofibril assembly GO:0030239 154 0.028
positive regulation of neurogenesis GO:0050769 4 0.028
cell part morphogenesis GO:0032990 152 0.028
cellular component assembly involved in morphogenesis GO:0010927 183 0.027
macromolecular complex assembly GO:0065003 193 0.027
Mouse
regulation of organelle organization GO:0033043 164 0.027
regulation of post embryonic development GO:0048580 260 0.026
regulation of cytoplasmic transport GO:1903649 3 0.026
negative regulation of nematode larval development GO:0061064 208 0.026
muscle cell development GO:0055001 158 0.026
regulation of cell cycle process GO:0010564 145 0.026
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.026
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.026
tube development GO:0035295 126 0.026
protein complex assembly GO:0006461 186 0.025
small molecule metabolic process GO:0044281 186 0.025
transcription from rna polymerase ii promoter GO:0006366 149 0.025
cellular nitrogen compound biosynthetic process GO:0044271 192 0.025
regulation of locomotion GO:0040012 161 0.024
striated muscle cell development GO:0055002 157 0.024
regulation of cell differentiation GO:0045595 81 0.024
secretion GO:0046903 147 0.024
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.024
molting cycle GO:0042303 281 0.024
cell cell signaling GO:0007267 118 0.024
nucleobase containing compound biosynthetic process GO:0034654 184 0.024
regulation of cell cycle GO:0051726 194 0.024
intracellular receptor signaling pathway GO:0030522 2 0.023
carboxylic acid biosynthetic process GO:0046394 21 0.023
cuticle development GO:0042335 100 0.023
Worm
tissue development GO:0009888 112 0.023
protein complex biogenesis GO:0070271 186 0.023
cell fate commitment GO:0045165 139 0.023
monocarboxylic acid biosynthetic process GO:0072330 13 0.023
cell morphogenesis involved in differentiation GO:0000904 112 0.022
nucleic acid templated transcription GO:0097659 169 0.022
sensory organ morphogenesis GO:0090596 2 0.022
striated muscle myosin thick filament assembly GO:0071688 138 0.022
protein modification process GO:0036211 207 0.021
regulation of meiotic cell cycle GO:0051445 136 0.021
oxoacid metabolic process GO:0043436 47 0.021
regulation of transcription dna templated GO:0006355 164 0.021
macromolecule catabolic process GO:0009057 202 0.021
transcription dna templated GO:0006351 168 0.021
myosin filament assembly GO:0031034 138 0.021
response to external stimulus GO:0009605 289 0.021
regulation of meiosis GO:0040020 94 0.021
muscle structure development GO:0061061 191 0.021
positive regulation of transcription dna templated GO:0045893 102 0.021
muscle tissue development GO:0060537 1 0.021
striated muscle cell differentiation GO:0051146 158 0.021
macromolecule modification GO:0043412 218 0.020
cell type specific apoptotic process GO:0097285 4 0.020
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.020
microtubule based process GO:0007017 182 0.020
regulation of nucleocytoplasmic transport GO:0046822 3 0.020
organonitrogen compound metabolic process GO:1901564 151 0.020
learning or memory GO:0007611 27 0.019
cellular protein modification process GO:0006464 207 0.019
collagen and cuticulin based cuticle development GO:0040002 99 0.019
Worm
response to mechanical stimulus GO:0009612 28 0.019
organic cyclic compound biosynthetic process GO:1901362 195 0.019
cell proliferation GO:0008283 116 0.019
rna biosynthetic process GO:0032774 169 0.019
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.019
response to abiotic stimulus GO:0009628 152 0.018
cellular response to abiotic stimulus GO:0071214 4 0.018
regulation of gene expression epigenetic GO:0040029 163 0.018
muscle cell differentiation GO:0042692 171 0.018
chromosome segregation GO:0007059 180 0.018
mrna metabolic process GO:0016071 31 0.018
regulation of response to stimulus GO:0048583 243 0.018
aromatic compound biosynthetic process GO:0019438 192 0.018
taxis GO:0042330 128 0.018
regulation of signal transduction GO:0009966 135 0.018
regulation of mitotic cell cycle GO:0007346 76 0.018
catabolic process GO:0009056 318 0.018
organic acid metabolic process GO:0006082 47 0.018
spindle organization GO:0007051 92 0.018
positive regulation of cell projection organization GO:0031346 4 0.018
regulation of nucleic acid templated transcription GO:1903506 165 0.018
mitotic spindle organization GO:0007052 81 0.018
myosin filament organization GO:0031033 138 0.017
intracellular signal transduction GO:0035556 96 0.017
posttranscriptional gene silencing by rna GO:0035194 143 0.017
muscle organ morphogenesis GO:0048644 4 0.017
phosphorus metabolic process GO:0006793 232 0.017
organic substance catabolic process GO:1901575 294 0.017
posttranscriptional regulation of gene expression GO:0010608 166 0.017
tube morphogenesis GO:0035239 79 0.017
carboxylic acid metabolic process GO:0019752 34 0.017
synaptic transmission GO:0007268 106 0.017
regulation of cell communication GO:0010646 176 0.017
negative regulation of neurogenesis GO:0050768 4 0.017
defense response GO:0006952 296 0.017
cellular protein complex assembly GO:0043623 178 0.017
negative regulation of gene expression epigenetic GO:0045814 2 0.017
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.017
epithelium development GO:0060429 68 0.017
mitotic nuclear division GO:0007067 89 0.017
gene silencing by rna GO:0031047 143 0.016
negative regulation of cellular metabolic process GO:0031324 95 0.016
Mouse
regulation of cellular ketone metabolic process GO:0010565 3 0.016
gene silencing GO:0016458 143 0.016
neurological system process GO:0050877 53 0.016
regulation of apoptotic signaling pathway GO:2001233 1 0.016
protein localization GO:0008104 205 0.016
regeneration GO:0031099 4 0.016
epithelial tube morphogenesis GO:0060562 1 0.015
posttranscriptional gene silencing GO:0016441 143 0.015
heterocycle biosynthetic process GO:0018130 187 0.015
regulation of signaling GO:0023051 172 0.015
single organism biosynthetic process GO:0044711 91 0.015
regulation of nuclear division GO:0051783 115 0.015
regulation of anatomical structure size GO:0090066 46 0.015
rna interference GO:0016246 137 0.015
positive regulation of cellular component organization GO:0051130 34 0.015
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.015
rna localization GO:0006403 3 0.015
regulation of cellular protein metabolic process GO:0032268 75 0.015
regulation of protein metabolic process GO:0051246 81 0.015
cellular catabolic process GO:0044248 199 0.015
positive regulation of vulval development GO:0040026 52 0.015
adult behavior GO:0030534 3 0.014
response to organic substance GO:0010033 131 0.014
establishment or maintenance of cell polarity GO:0007163 63 0.014
regulation of localization GO:0032879 194 0.014
canonical wnt signaling pathway GO:0060070 3 0.014
lipid biosynthetic process GO:0008610 28 0.014
embryonic body morphogenesis GO:0010172 49 0.014
Worm
digestive tract development GO:0048565 122 0.014
digestive system development GO:0055123 122 0.014
positive regulation of rna metabolic process GO:0051254 103 0.014
positive regulation of neuron projection development GO:0010976 4 0.014
regulation of protein import into nucleus GO:0042306 3 0.014
regulation of neuron projection development GO:0010975 31 0.014
regulation of cell morphogenesis GO:0022604 40 0.014
organic acid biosynthetic process GO:0016053 21 0.014
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.014
detection of external stimulus GO:0009581 4 0.014
regulation of response to wounding GO:1903034 1 0.014
regulation of cell death GO:0010941 65 0.014
organic substance transport GO:0071702 113 0.014
regulation of lipid metabolic process GO:0019216 4 0.014
regulation of protein targeting GO:1903533 3 0.013
response to acid chemical GO:0001101 4 0.013
organelle localization GO:0051640 127 0.013
meiotic cell cycle process GO:1903046 170 0.013
neuromuscular junction development GO:0007528 2 0.013
cytokinesis GO:0000910 80 0.013
regulation of cell proliferation GO:0042127 105 0.013
response to temperature stimulus GO:0009266 66 0.013
dendrite development GO:0016358 42 0.013
positive regulation of protein transport GO:0051222 4 0.013
regulation of rna biosynthetic process GO:2001141 165 0.013
phosphate containing compound metabolic process GO:0006796 232 0.013
adult locomotory behavior GO:0008344 1 0.013
positive regulation of rna biosynthetic process GO:1902680 102 0.013
translation GO:0006412 37 0.013
locomotory behavior GO:0007626 40 0.013
rrna metabolic process GO:0016072 3 0.013
positive regulation of cell migration GO:0030335 3 0.012
chemosensory behavior GO:0007635 33 0.012
ribonucleoprotein complex assembly GO:0022618 4 0.012
Mouse
single organism intracellular transport GO:1902582 70 0.012
muscle system process GO:0003012 43 0.012
Worm
negative regulation of neuron differentiation GO:0045665 4 0.012
axon development GO:0061564 163 0.012
meiotic chromosome segregation GO:0045132 139 0.012
positive regulation of stem cell differentiation GO:2000738 1 0.012
regulation of protein localization GO:0032880 50 0.012
small molecule biosynthetic process GO:0044283 38 0.012
axonal fasciculation GO:0007413 79 0.012
cell cycle switching mitotic to meiotic cell cycle GO:0051728 35 0.012
pattern specification process GO:0007389 59 0.012
regulation of intracellular signal transduction GO:1902531 77 0.012
regulation of canonical wnt signaling pathway GO:0060828 1 0.012
mating GO:0007618 34 0.012
phagocytosis GO:0006909 115 0.012
male mating behavior GO:0060179 26 0.012
pronuclear migration GO:0035046 51 0.011
regulation of neurogenesis GO:0050767 40 0.011
regulation of cellular amine metabolic process GO:0033238 0 0.011
single fertilization GO:0007338 61 0.011
nucleus localization GO:0051647 55 0.011
regulation of transport GO:0051049 91 0.011
nematode male tail tip morphogenesis GO:0045138 77 0.011
regulation of oviposition GO:0046662 43 0.011
cellular amino acid metabolic process GO:0006520 15 0.011
lipid metabolic process GO:0006629 77 0.011
carbohydrate derivative metabolic process GO:1901135 141 0.011
neurotransmitter transport GO:0006836 32 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.011
Mouse
regulation of cell development GO:0060284 49 0.011
rrna processing GO:0006364 3 0.011
establishment of organelle localization GO:0051656 123 0.011
negative regulation of response to stimulus GO:0048585 73 0.011
establishment of nucleus localization GO:0040023 55 0.011
regulation of reproductive process GO:2000241 66 0.011
pharynx development GO:0060465 51 0.011
regulation of cellular amino acid metabolic process GO:0006521 0 0.011
single organism cellular localization GO:1902580 72 0.011
g1 s transition of mitotic cell cycle GO:0000082 2 0.011
positive regulation of nucleic acid templated transcription GO:1903508 102 0.011
fertilization GO:0009566 63 0.011
male anatomical structure morphogenesis GO:0090598 78 0.011
apoptotic cell clearance GO:0043277 111 0.011
positive regulation of post embryonic development GO:0048582 54 0.011
regulation of neurotransmitter levels GO:0001505 36 0.011
mating behavior GO:0007617 32 0.010
oocyte axis specification GO:0007309 2 0.010
positive regulation of cell cycle GO:0045787 55 0.010
cellular amine metabolic process GO:0044106 15 0.010
cell cycle g1 s phase transition GO:0044843 2 0.010
regulation of cation channel activity GO:2001257 3 0.010
positive regulation of nematode larval development GO:0061063 54 0.010
protein catabolic process GO:0030163 162 0.010
amine metabolic process GO:0009308 15 0.010
cell substrate adhesion GO:0031589 1 0.010
establishment of spindle localization GO:0051293 51 0.010
cellular response to chemical stimulus GO:0070887 129 0.010
regulation of nervous system development GO:0051960 41 0.010
digestive tract morphogenesis GO:0048546 76 0.010
calcium mediated signaling GO:0019722 3 0.010

unc-75 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.021
cancer DOID:162 0 0.012
disease of cellular proliferation DOID:14566 0 0.012
organ system cancer DOID:0050686 0 0.012
nervous system disease DOID:863 0 0.012