Caenorhabditis elegans

10 known processes

mdt-28 (CELE_W01A8.1)

Protein MDT-28

mdt-28 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
single organism signaling GO:0044700 401 0.572
post embryonic development GO:0009791 2152 0.546
embryo development ending in birth or egg hatching GO:0009792 2992 0.530
cell development GO:0048468 696 0.388
vesicle mediated transport GO:0016192 852 0.381
embryo development GO:0009790 3052 0.378
multicellular organism reproduction GO:0032504 819 0.377
locomotion GO:0040011 1634 0.353
multi organism reproductive process GO:0044703 867 0.306
growth GO:0040007 562 0.299
determination of adult lifespan GO:0008340 812 0.298
sexual reproduction GO:0019953 546 0.294
cellular component movement GO:0006928 388 0.270
response to external stimulus GO:0009605 289 0.265
germ cell development GO:0007281 351 0.259
multicellular organismal reproductive process GO:0048609 815 0.253
aging GO:0007568 812 0.252
developmental process involved in reproduction GO:0003006 1165 0.228
reproductive structure development GO:0048608 850 0.225
localization of cell GO:0051674 313 0.223
response to chemical GO:0042221 356 0.223
signal transduction GO:0007165 317 0.222
signaling GO:0023052 401 0.217
establishment of localization GO:0051234 1171 0.198
hermaphrodite genitalia development GO:0040035 734 0.185
multicellular organism growth GO:0035264 385 0.185
multicellular organismal reproductive behavior GO:0033057 384 0.177
regulation of biological quality GO:0065008 741 0.176
protein metabolic process GO:0019538 422 0.173
cellular localization GO:0051641 360 0.172
development of primary sexual characteristics GO:0045137 840 0.167
reproductive behavior GO:0019098 387 0.166
organic substance catabolic process GO:1901575 294 0.163
developmental growth GO:0048589 412 0.156
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.155
response to organic substance GO:0010033 131 0.154
multicellular organismal aging GO:0010259 812 0.151
macromolecule localization GO:0033036 771 0.148
regulation of developmental growth GO:0048638 389 0.148
regulation of growth GO:0040008 409 0.148
regulation of multicellular organism growth GO:0040014 373 0.147
organ development GO:0048513 1102 0.143
behavior GO:0007610 527 0.143
single organism transport GO:0044765 447 0.139
regulation of primary metabolic process GO:0080090 292 0.138
cellular response to topologically incorrect protein GO:0035967 76 0.135
nervous system development GO:0007399 253 0.134
positive regulation of multicellular organismal process GO:0051240 417 0.126
purine nucleoside triphosphate catabolic process GO:0009146 72 0.124
positive regulation of developmental growth GO:0048639 354 0.124
response to topologically incorrect protein GO:0035966 82 0.123
multi organism reproductive behavior GO:0044705 387 0.122
receptor mediated endocytosis GO:0006898 715 0.121
multi multicellular organism process GO:0044706 390 0.121
cell death GO:0008219 547 0.119
establishment of localization in cell GO:0051649 318 0.118
regulation of rna metabolic process GO:0051252 173 0.115
regulation of cellular metabolic process GO:0031323 305 0.115
sex differentiation GO:0007548 909 0.111
transport GO:0006810 1093 0.108
programmed cell death GO:0012501 500 0.105
regulation of locomotion GO:0040012 161 0.105
neuron projection development GO:0031175 187 0.104
apoptotic process GO:0006915 478 0.103
macromolecular complex subunit organization GO:0043933 320 0.100
lipid localization GO:0010876 573 0.097
negative regulation of biological process GO:0048519 567 0.097
positive regulation of multicellular organism growth GO:0040018 352 0.094
positive regulation of cellular metabolic process GO:0031325 178 0.092
single organism reproductive process GO:0044702 1196 0.092
regulation of developmental process GO:0050793 684 0.091
small molecule metabolic process GO:0044281 186 0.090
lipid storage GO:0019915 565 0.086
reproductive system development GO:0061458 850 0.085
endocytosis GO:0006897 819 0.085
cell motility GO:0048870 313 0.085
death GO:0016265 547 0.081
maintenance of location GO:0051235 580 0.079
phosphorus metabolic process GO:0006793 232 0.078
negative regulation of developmental process GO:0051093 227 0.077
negative regulation of multicellular organismal process GO:0051241 236 0.077
catabolic process GO:0009056 318 0.076
protein modification process GO:0036211 207 0.075
response to oxygen containing compound GO:1901700 44 0.075
cellular component morphogenesis GO:0032989 318 0.074
response to unfolded protein GO:0006986 71 0.073
positive regulation of growth GO:0045927 369 0.072
defense response to other organism GO:0098542 100 0.072
positive regulation of cellular process GO:0048522 332 0.072
defense response GO:0006952 296 0.071
regulation of response to stimulus GO:0048583 243 0.071
macromolecular complex assembly GO:0065003 193 0.071
oogenesis GO:0048477 229 0.070
cell surface receptor signaling pathway GO:0007166 149 0.070
cell projection organization GO:0030030 231 0.070
nucleotide metabolic process GO:0009117 108 0.069
generation of neurons GO:0048699 235 0.066
positive regulation of metabolic process GO:0009893 187 0.065
regulation of multicellular organismal process GO:0051239 726 0.065
system process GO:0003008 136 0.064
response to endoplasmic reticulum stress GO:0034976 71 0.064
anatomical structure formation involved in morphogenesis GO:0048646 250 0.063
multi organism behavior GO:0051705 389 0.062
regulation of response to wounding GO:1903034 1 0.062
macromolecule modification GO:0043412 218 0.062
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.061
neuron development GO:0048666 199 0.061
response to biotic stimulus GO:0009607 101 0.061
response to external biotic stimulus GO:0043207 101 0.060
endosomal transport GO:0016197 26 0.060
regulation of metabolic process GO:0019222 478 0.060
cellular response to organic substance GO:0071310 119 0.059
transmembrane transport GO:0055085 110 0.057
single organism intracellular transport GO:1902582 70 0.057
regulation of localization GO:0032879 194 0.056
purine nucleoside metabolic process GO:0042278 92 0.055
cellular response to stress GO:0033554 162 0.055
organonitrogen compound metabolic process GO:1901564 151 0.054
response to wounding GO:0009611 4 0.052
actin cytoskeleton organization GO:0030036 184 0.052
negative regulation of cellular process GO:0048523 239 0.052
cytoskeleton organization GO:0007010 339 0.051
cell division GO:0051301 262 0.051
cellular lipid metabolic process GO:0044255 40 0.051
intracellular transport GO:0046907 77 0.050
cellular protein modification process GO:0006464 207 0.049
gamete generation GO:0007276 461 0.049
positive regulation of developmental process GO:0051094 408 0.048
regulation of cell communication GO:0010646 176 0.048
oviposition GO:0018991 364 0.047
body morphogenesis GO:0010171 620 0.047
organelle organization GO:0006996 783 0.046
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.046
ion transport GO:0006811 113 0.046
muscle structure development GO:0061061 191 0.045
cellular macromolecular complex assembly GO:0034622 184 0.045
regulation of signaling GO:0023051 172 0.045
cellular component assembly GO:0022607 293 0.044
protein complex subunit organization GO:0071822 280 0.044
nucleoside metabolic process GO:0009116 99 0.044
membrane organization GO:0061024 135 0.043
single organism organelle organization GO:1902589 501 0.043
purine containing compound catabolic process GO:0072523 75 0.043
sensory organ morphogenesis GO:0090596 2 0.042
chemical homeostasis GO:0048878 29 0.042
regulation of signal transduction GO:0009966 135 0.041
glycosyl compound metabolic process GO:1901657 100 0.041
establishment of organelle localization GO:0051656 123 0.041
regulation of cell motility GO:2000145 57 0.041
regulation of macromolecule metabolic process GO:0060255 421 0.041
skeletal muscle organ development GO:0060538 3 0.041
striated muscle cell differentiation GO:0051146 158 0.038
response to heat GO:0009408 50 0.038
gene expression GO:0010467 412 0.038
nucleoside phosphate metabolic process GO:0006753 108 0.038
response to other organism GO:0051707 101 0.037
regulation of nitrogen compound metabolic process GO:0051171 222 0.037
regulation of transport GO:0051049 91 0.037
regulation of cellular component organization GO:0051128 248 0.037
neurogenesis GO:0022008 236 0.036
protein localization GO:0008104 205 0.036
actin filament based process GO:0030029 191 0.036
muscle cell differentiation GO:0042692 171 0.036
regulation of cellular catabolic process GO:0031329 51 0.036
cellular macromolecule localization GO:0070727 75 0.035
cellular protein localization GO:0034613 75 0.034
cell migration GO:0016477 306 0.034
regulation of lipid metabolic process GO:0019216 4 0.034
synaptic vesicle endocytosis GO:0048488 3 0.034
nucleoside triphosphate catabolic process GO:0009143 72 0.034
regulation of cellular biosynthetic process GO:0031326 189 0.033
response to acid chemical GO:0001101 4 0.033
cellular biosynthetic process GO:0044249 315 0.031
regulation of intracellular signal transduction GO:1902531 77 0.031
cell part morphogenesis GO:0032990 152 0.031
nucleobase containing compound metabolic process GO:0006139 406 0.031
cell cycle process GO:0022402 482 0.030
nucleoside phosphate catabolic process GO:1901292 77 0.030
cell proliferation GO:0008283 116 0.030
genitalia development GO:0048806 741 0.029
negative regulation of gene expression GO:0010629 217 0.029
cell cycle GO:0007049 526 0.029
regulation of cell migration GO:0030334 55 0.029
neuron differentiation GO:0030182 217 0.029
tissue development GO:0009888 112 0.028
cellular component biogenesis GO:0044085 297 0.028
regulation of phosphorus metabolic process GO:0051174 81 0.028
single organism localization GO:1902578 518 0.028
regulation of molecular function GO:0065009 89 0.028
embryonic morphogenesis GO:0048598 152 0.028
carboxylic acid metabolic process GO:0019752 34 0.028
organophosphate catabolic process GO:0046434 81 0.028
single organism cellular localization GO:1902580 72 0.028
regulation of phosphate metabolic process GO:0019220 81 0.027
purine nucleoside triphosphate metabolic process GO:0009144 87 0.027
head development GO:0060322 1 0.027
biosynthetic process GO:0009058 323 0.027
negative regulation of ion transmembrane transport GO:0034766 3 0.027
negative regulation of cation channel activity GO:2001258 2 0.026
gonad development GO:0008406 840 0.026
purine nucleoside catabolic process GO:0006152 75 0.026
positive regulation of rna biosynthetic process GO:1902680 102 0.026
macromolecule catabolic process GO:0009057 202 0.026
post embryonic organ development GO:0048569 336 0.025
phosphate containing compound metabolic process GO:0006796 232 0.025
cellular response to unfolded protein GO:0034620 71 0.025
response to anesthetic GO:0072347 1 0.025
cellular nitrogen compound biosynthetic process GO:0044271 192 0.025
organophosphate metabolic process GO:0019637 125 0.025
neuron projection morphogenesis GO:0048812 114 0.025
p38mapk cascade GO:0038066 2 0.024
negative regulation of signal transduction GO:0009968 60 0.024
intercellular transport GO:0010496 1 0.024
protein complex biogenesis GO:0070271 186 0.024
amine metabolic process GO:0009308 15 0.024
purine ribonucleotide metabolic process GO:0009150 95 0.024
cellular response to chemical stimulus GO:0070887 129 0.023
actomyosin structure organization GO:0031032 154 0.023
negative regulation of vulval development GO:0040027 206 0.023
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.023
cell morphogenesis GO:0000902 163 0.023
enzyme linked receptor protein signaling pathway GO:0007167 50 0.022
organonitrogen compound catabolic process GO:1901565 90 0.022
muscle cell development GO:0055001 158 0.022
defense response to bacterium GO:0042742 86 0.022
regulation of multicellular organismal development GO:2000026 317 0.022
nucleobase containing small molecule metabolic process GO:0055086 115 0.022
regulation of gene expression GO:0010468 366 0.022
organelle fission GO:0048285 363 0.022
striated muscle cell development GO:0055002 157 0.022
secretion by cell GO:0032940 138 0.021
nucleobase containing compound catabolic process GO:0034655 114 0.021
digestive tract development GO:0048565 122 0.021
ribonucleoside triphosphate metabolic process GO:0009199 87 0.021
heterocycle biosynthetic process GO:0018130 187 0.021
cellular macromolecule biosynthetic process GO:0034645 247 0.021
nucleic acid metabolic process GO:0090304 299 0.021
cellular catabolic process GO:0044248 199 0.021
regulation of cellular protein metabolic process GO:0032268 75 0.020
response to temperature stimulus GO:0009266 66 0.020
negative regulation of metabolic process GO:0009892 240 0.020
organic substance transport GO:0071702 113 0.020
protein complex assembly GO:0006461 186 0.020
meiotic cell cycle GO:0051321 335 0.020
axon development GO:0061564 163 0.020
organic cyclic compound catabolic process GO:1901361 119 0.020
endoplasmic reticulum unfolded protein response GO:0030968 66 0.020
lipid metabolic process GO:0006629 77 0.020
cell type specific apoptotic process GO:0097285 4 0.019
purine ribonucleoside metabolic process GO:0046128 92 0.019
regulation of macromolecule biosynthetic process GO:0010556 189 0.019
regulation of transcription dna templated GO:0006355 164 0.019
protein catabolic process GO:0030163 162 0.019
regulation of vulval development GO:0040028 248 0.019
response to inorganic substance GO:0010035 50 0.019
response to abiotic stimulus GO:0009628 152 0.018
ion transmembrane transport GO:0034220 91 0.018
regulation of cell division GO:0051302 142 0.018
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 34 0.018
single organism catabolic process GO:0044712 129 0.018
negative regulation of growth GO:0045926 12 0.018
negative regulation of signaling GO:0023057 61 0.018
oocyte development GO:0048599 44 0.018
organic substance biosynthetic process GO:1901576 323 0.018
regulation of cytoplasmic transport GO:1903649 3 0.017
regulation of cation channel activity GO:2001257 3 0.017
immune response GO:0006955 192 0.017
cellular protein metabolic process GO:0044267 279 0.017
apoptotic cell clearance GO:0043277 111 0.017
secretion GO:0046903 147 0.017
cellular amine metabolic process GO:0044106 15 0.017
positive regulation of phosphate metabolic process GO:0045937 56 0.017
cell projection morphogenesis GO:0048858 148 0.017
carbohydrate derivative catabolic process GO:1901136 82 0.017
response to bacterium GO:0009617 86 0.016
organic cyclic compound biosynthetic process GO:1901362 195 0.016
ribonucleotide catabolic process GO:0009261 75 0.016
regulation of multi organism process GO:0043900 69 0.016
intracellular receptor signaling pathway GO:0030522 2 0.016
muscle system process GO:0003012 43 0.016
female gamete generation GO:0007292 254 0.016
purine containing compound metabolic process GO:0072521 95 0.016
mitotic cell cycle process GO:1903047 194 0.016
aromatic compound biosynthetic process GO:0019438 192 0.016
ribonucleoside metabolic process GO:0009119 98 0.016
meiotic nuclear division GO:0007126 300 0.016
cellular component assembly involved in morphogenesis GO:0010927 183 0.016
transcription dna templated GO:0006351 168 0.016
synaptic vesicle recycling GO:0036465 3 0.016
rna metabolic process GO:0016070 228 0.015
calcium mediated signaling GO:0019722 3 0.015
anion transport GO:0006820 30 0.015
regulation of exocytosis GO:0017157 1 0.015
myosin filament organization GO:0031033 138 0.015
regulation of meiotic cell cycle GO:0051445 136 0.015
phagocytosis engulfment GO:0006911 98 0.015
regulation of cell proliferation GO:0042127 105 0.015
myofibril assembly GO:0030239 154 0.015
aromatic compound catabolic process GO:0019439 116 0.015
epithelial cell proliferation GO:0050673 1 0.015
regulation of phosphorylation GO:0042325 45 0.015
regulation of catalytic activity GO:0050790 78 0.015
regulation of nematode larval development GO:0061062 260 0.015
regulation of neuromuscular synaptic transmission GO:1900073 1 0.015
organic acid metabolic process GO:0006082 47 0.015
cellular nitrogen compound catabolic process GO:0044270 119 0.014
positive regulation of macromolecule metabolic process GO:0010604 149 0.014
organelle assembly GO:0070925 214 0.014
protein oligomerization GO:0051259 4 0.014
nucleoside catabolic process GO:0009164 78 0.014
purine nucleotide metabolic process GO:0006163 95 0.014
apoptotic mitochondrial changes GO:0008637 2 0.014
spindle organization GO:0007051 92 0.014
ribose phosphate metabolic process GO:0019693 99 0.014
glycosyl compound catabolic process GO:1901658 79 0.014
negative regulation of transmembrane transport GO:0034763 3 0.014
actin cytoskeleton reorganization GO:0031532 4 0.013
translation GO:0006412 37 0.013
nucleic acid templated transcription GO:0097659 169 0.013
posttranscriptional regulation of gene expression GO:0010608 166 0.013
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.013
purine nucleotide catabolic process GO:0006195 75 0.013
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.013
nucleotide catabolic process GO:0009166 77 0.013
regulation of cell death GO:0010941 65 0.013
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.013
regulation of cell cycle GO:0051726 194 0.013
organelle localization GO:0051640 127 0.012
nematode male tail tip morphogenesis GO:0045138 77 0.012
intracellular signal transduction GO:0035556 96 0.012
myosin filament assembly GO:0031034 138 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.012
organic hydroxy compound metabolic process GO:1901615 25 0.012
lysosomal transport GO:0007041 5 0.012
nucleoside monophosphate metabolic process GO:0009123 46 0.012
protein transport GO:0015031 45 0.012
response to oxidative stress GO:0006979 42 0.012
positive regulation of transcription from rna polymerase ii promoter in response to stress GO:0036003 2 0.012
response to extracellular stimulus GO:0009991 38 0.012
positive regulation of cell migration GO:0030335 3 0.011
protein transmembrane transport GO:0071806 4 0.011
oxoacid metabolic process GO:0043436 47 0.011
positive regulation of protein transport GO:0051222 4 0.011
phosphorylation GO:0016310 116 0.011
regulation of organelle organization GO:0033043 164 0.011
negative regulation of cell communication GO:0010648 61 0.011
positive regulation of signal transduction GO:0009967 40 0.011
macromolecule biosynthetic process GO:0009059 250 0.011
digestive tract morphogenesis GO:0048546 76 0.011
ribonucleoside triphosphate catabolic process GO:0009203 72 0.011
regulation of cellular ketone metabolic process GO:0010565 3 0.011
cell morphogenesis involved in differentiation GO:0000904 112 0.011
purine ribonucleotide catabolic process GO:0009154 75 0.011
striated muscle myosin thick filament assembly GO:0071688 138 0.011
carbohydrate derivative metabolic process GO:1901135 141 0.011
regulation of reproductive process GO:2000241 66 0.011
male sex differentiation GO:0046661 86 0.011
negative regulation of response to stimulus GO:0048585 73 0.011
regulation of anatomical structure morphogenesis GO:0022603 51 0.011
cellular protein complex assembly GO:0043623 178 0.011
feeding behavior GO:0007631 70 0.010
striated muscle contraction GO:0006941 17 0.010
microtubule based process GO:0007017 182 0.010
ribonucleoside catabolic process GO:0042454 77 0.010
negative regulation of macromolecule metabolic process GO:0010605 229 0.010

mdt-28 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.048
nervous system disease DOID:863 0 0.015