Caenorhabditis elegans

83 known processes

pmk-3 (CELE_F42G8.4)

Protein PMK-3

pmk-3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
gamete generation GO:0007276 461 0.604
Worm
vesicle mediated transport GO:0016192 852 0.467
embryo development GO:0009790 3052 0.457
Worm
female gamete generation GO:0007292 254 0.429
Worm
embryo development ending in birth or egg hatching GO:0009792 2992 0.416
Worm
sexual reproduction GO:0019953 546 0.412
Yeast Worm
receptor mediated endocytosis GO:0006898 715 0.350
single organism reproductive process GO:0044702 1196 0.349
Yeast Worm
establishment of localization GO:0051234 1171 0.331
Worm
multicellular organismal reproductive process GO:0048609 815 0.330
Worm
aging GO:0007568 812 0.311
Worm
organic cyclic compound biosynthetic process GO:1901362 195 0.311
Yeast Worm
determination of adult lifespan GO:0008340 812 0.308
Worm
stress activated mapk cascade GO:0051403 10 0.305
Worm
positive regulation of transcription from rna polymerase ii promoter involved in defense response to gram negative bacterium GO:1902097 4 0.300
Worm
multicellular organism reproduction GO:0032504 819 0.290
Worm
gene expression GO:0010467 412 0.285
Yeast Worm
regulation of cell differentiation GO:0045595 81 0.274
Yeast
organ development GO:0048513 1102 0.257
Worm
transport GO:0006810 1093 0.256
Worm
endocytosis GO:0006897 819 0.249
multicellular organismal aging GO:0010259 812 0.208
Worm
p38mapk cascade GO:0038066 2 0.208
Worm
nucleobase containing compound biosynthetic process GO:0034654 184 0.196
Yeast Worm
macromolecule localization GO:0033036 771 0.193
Worm
positive regulation of nucleic acid templated transcription GO:1903508 102 0.187
Yeast Worm
cellular biosynthetic process GO:0044249 315 0.186
Yeast Worm
developmental process involved in reproduction GO:0003006 1165 0.185
Yeast Worm
germ cell development GO:0007281 351 0.174
Worm
locomotion GO:0040011 1634 0.163
post embryonic development GO:0009791 2152 0.163
Worm
regulation of developmental process GO:0050793 684 0.163
Yeast
cellular nitrogen compound biosynthetic process GO:0044271 192 0.158
Yeast Worm
reproductive system development GO:0061458 850 0.155
Worm
regulation of gene expression GO:0010468 366 0.154
Yeast Worm
death GO:0016265 547 0.151
biosynthetic process GO:0009058 323 0.150
Yeast Worm
regulation of biological quality GO:0065008 741 0.150
sex differentiation GO:0007548 909 0.149
Worm
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.148
Yeast Worm
regulation of multicellular organismal process GO:0051239 726 0.147
heterocycle biosynthetic process GO:0018130 187 0.146
Yeast Worm
reproductive structure development GO:0048608 850 0.138
Worm
jnk cascade GO:0007254 8 0.133
Worm
cell development GO:0048468 696 0.127
organic substance biosynthetic process GO:1901576 323 0.127
Yeast Worm
positive regulation of cellular metabolic process GO:0031325 178 0.126
Yeast Worm
hyperosmotic response GO:0006972 19 0.126
Yeast Worm
positive regulation of cellular process GO:0048522 332 0.124
Yeast Worm
single organism transport GO:0044765 447 0.121
Worm
regulation of rna metabolic process GO:0051252 173 0.121
Yeast Worm
positive regulation of metabolic process GO:0009893 187 0.119
Yeast Worm
positive regulation of gene expression GO:0010628 112 0.119
Yeast Worm
defense response to other organism GO:0098542 100 0.116
Worm
growth GO:0040007 562 0.115
positive regulation of rna metabolic process GO:0051254 103 0.114
Yeast Worm
tissue development GO:0009888 112 0.114
single organism localization GO:1902578 518 0.109
Worm
signaling GO:0023052 401 0.108
regulation of macromolecule metabolic process GO:0060255 421 0.107
Yeast Worm
protein metabolic process GO:0019538 422 0.102
hermaphrodite genitalia development GO:0040035 734 0.102
Worm
response to external stimulus GO:0009605 289 0.101
Worm
cell cycle GO:0007049 526 0.100
Yeast Worm
multicellular organism growth GO:0035264 385 0.100
regulation of growth GO:0040008 409 0.100
cellular component assembly GO:0022607 293 0.095
lipid localization GO:0010876 573 0.092
muscle cell development GO:0055001 158 0.089
single organism cellular localization GO:1902580 72 0.088
Worm
genitalia development GO:0048806 741 0.087
Worm
organelle organization GO:0006996 783 0.086
developmental growth GO:0048589 412 0.080
nucleic acid templated transcription GO:0097659 169 0.080
Yeast Worm
cellular component morphogenesis GO:0032989 318 0.079
macromolecule biosynthetic process GO:0009059 250 0.079
Yeast Worm
regulation of biosynthetic process GO:0009889 189 0.077
Yeast Worm
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.076
Yeast Worm
cytoskeleton organization GO:0007010 339 0.076
muscle tissue development GO:0060537 1 0.075
stress activated protein kinase signaling cascade GO:0031098 10 0.075
Worm
acetylcholine metabolic process GO:0008291 4 0.073
nucleic acid metabolic process GO:0090304 299 0.073
Yeast Worm
regulation of developmental growth GO:0048638 389 0.072
positive regulation of multicellular organismal process GO:0051240 417 0.072
regulation of cellular component organization GO:0051128 248 0.072
transcription dna templated GO:0006351 168 0.072
Yeast Worm
cellular macromolecule biosynthetic process GO:0034645 247 0.071
Yeast Worm
negative regulation of organ growth GO:0046621 1 0.071
multi organism reproductive behavior GO:0044705 387 0.070
programmed cell death GO:0012501 500 0.069
positive regulation of growth GO:0045927 369 0.069
macromolecular complex subunit organization GO:0043933 320 0.069
regulation of multicellular organism growth GO:0040014 373 0.068
regulation of metabolic process GO:0019222 478 0.065
Yeast Worm
lipid storage GO:0019915 565 0.065
response to wounding GO:0009611 4 0.064
positive regulation of stress activated mapk cascade GO:0032874 3 0.064
muscle structure development GO:0061061 191 0.063
maintenance of location GO:0051235 580 0.060
small molecule metabolic process GO:0044281 186 0.060
protein complex subunit organization GO:0071822 280 0.059
muscle cell differentiation GO:0042692 171 0.058
regulation of nitrogen compound metabolic process GO:0051171 222 0.058
Yeast Worm
positive regulation of developmental process GO:0051094 408 0.058
positive regulation of developmental growth GO:0048639 354 0.057
regulation of cellular metabolic process GO:0031323 305 0.056
Yeast Worm
posttranscriptional regulation of gene expression GO:0010608 166 0.056
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.055
canonical wnt signaling pathway GO:0060070 3 0.054
positive regulation of biosynthetic process GO:0009891 109 0.052
Yeast Worm
rna biosynthetic process GO:0032774 169 0.051
Yeast Worm
nucleobase containing compound metabolic process GO:0006139 406 0.050
Yeast Worm
organelle localization GO:0051640 127 0.050
Worm
cellular response to inorganic substance GO:0071241 3 0.050
fatty acid metabolic process GO:0006631 16 0.049
aromatic compound biosynthetic process GO:0019438 192 0.049
Yeast Worm
protein phosphorylation GO:0006468 85 0.048
apoptotic process GO:0006915 478 0.048
transcription from rna polymerase ii promoter GO:0006366 149 0.048
Yeast Worm
response to transition metal nanoparticle GO:1990267 18 0.047
Worm
multi multicellular organism process GO:0044706 390 0.047
macromolecule catabolic process GO:0009057 202 0.047
multi organism reproductive process GO:0044703 867 0.047
Yeast Worm
positive regulation of multicellular organism growth GO:0040018 352 0.045
positive regulation of jnk cascade GO:0046330 3 0.045
cell cycle process GO:0022402 482 0.045
Yeast
phosphate containing compound metabolic process GO:0006796 232 0.045
regulation of cell development GO:0060284 49 0.044
striated muscle cell differentiation GO:0051146 158 0.044
regulation of macromolecule biosynthetic process GO:0010556 189 0.043
Yeast Worm
striated muscle cell development GO:0055002 157 0.042
cellular localization GO:0051641 360 0.042
Worm
establishment of localization in cell GO:0051649 318 0.042
Worm
organic substance catabolic process GO:1901575 294 0.041
posttranscriptional gene silencing GO:0016441 143 0.041
cell death GO:0008219 547 0.040
development of primary sexual characteristics GO:0045137 840 0.040
Worm
gonad development GO:0008406 840 0.039
Worm
synaptic transmission GO:0007268 106 0.038
negative regulation of metabolic process GO:0009892 240 0.038
regulation of multi organism process GO:0043900 69 0.038
rna metabolic process GO:0016070 228 0.038
Yeast Worm
regeneration GO:0031099 4 0.037
phosphorus metabolic process GO:0006793 232 0.037
cellular response to abiotic stimulus GO:0071214 4 0.037
Yeast
defense response to gram negative bacterium GO:0050829 64 0.036
Worm
lipid metabolic process GO:0006629 77 0.036
cellular component biogenesis GO:0044085 297 0.036
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.035
Worm
body morphogenesis GO:0010171 620 0.035
membrane organization GO:0061024 135 0.035
acetate ester metabolic process GO:1900619 4 0.035
positive regulation of rna biosynthetic process GO:1902680 102 0.035
Yeast Worm
regulation of rna biosynthetic process GO:2001141 165 0.034
Yeast Worm
myosin filament assembly GO:0031034 138 0.034
regulation of nucleic acid templated transcription GO:1903506 165 0.034
Yeast Worm
gene silencing GO:0016458 143 0.033
gene silencing by rna GO:0031047 143 0.033
cellular macromolecular complex assembly GO:0034622 184 0.032
rna localization GO:0006403 3 0.032
reproductive behavior GO:0019098 387 0.032
protein localization GO:0008104 205 0.032
Worm
response to inorganic substance GO:0010035 50 0.031
Worm
cellular protein localization GO:0034613 75 0.031
Worm
regulation of reproductive process GO:2000241 66 0.030
vulval development GO:0040025 333 0.030
oviposition GO:0018991 364 0.030
localization of cell GO:0051674 313 0.030
multicellular organismal reproductive behavior GO:0033057 384 0.030
positive regulation of cellular biosynthetic process GO:0031328 109 0.030
Yeast Worm
response to bacterium GO:0009617 86 0.030
Worm
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.030
regulation of cellular biosynthetic process GO:0031326 189 0.030
Yeast Worm
single organism signaling GO:0044700 401 0.029
cytokinesis GO:0000910 80 0.029
response to osmotic stress GO:0006970 29 0.029
cell motility GO:0048870 313 0.029
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.029
Yeast Worm
protein modification process GO:0036211 207 0.029
posttranscriptional gene silencing by rna GO:0035194 143 0.028
skin development GO:0043588 24 0.028
behavior GO:0007610 527 0.028
oogenesis GO:0048477 229 0.028
Worm
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.027
Yeast Worm
establishment of organelle localization GO:0051656 123 0.027
Worm
regulation of primary metabolic process GO:0080090 292 0.027
Yeast Worm
secretion GO:0046903 147 0.027
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.027
intracellular protein transmembrane transport GO:0065002 4 0.027
innate immune response GO:0045087 190 0.027
Worm
protein complex assembly GO:0006461 186 0.027
skeletal muscle organ development GO:0060538 3 0.027
protein import GO:0017038 9 0.026
cell type specific apoptotic process GO:0097285 4 0.026
actomyosin structure organization GO:0031032 154 0.026
cell maturation GO:0048469 26 0.026
Worm
regulation of bmp signaling pathway GO:0030510 3 0.026
multi organism behavior GO:0051705 389 0.025
meiotic nuclear division GO:0007126 300 0.025
Worm
rna interference GO:0016246 137 0.025
organelle fission GO:0048285 363 0.024
Worm
cellular protein modification process GO:0006464 207 0.024
apoptotic cell clearance GO:0043277 111 0.024
pole plasm assembly GO:0007315 2 0.024
positive regulation of phosphate metabolic process GO:0045937 56 0.024
negative regulation of developmental process GO:0051093 227 0.024
Yeast
negative regulation of cellular process GO:0048523 239 0.024
Yeast
regulation of protein targeting GO:1903533 3 0.024
negative regulation of biological process GO:0048519 567 0.023
Yeast
myofibril assembly GO:0030239 154 0.023
regulation of neurotransmitter levels GO:0001505 36 0.022
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.022
Yeast Worm
engulfment of apoptotic cell GO:0043652 94 0.022
oxoacid metabolic process GO:0043436 47 0.022
regulation of organ morphogenesis GO:2000027 4 0.022
oocyte development GO:0048599 44 0.022
Worm
cell surface receptor signaling pathway GO:0007166 149 0.022
response to external biotic stimulus GO:0043207 101 0.021
Worm
organic acid metabolic process GO:0006082 47 0.021
oocyte axis specification GO:0007309 2 0.021
response to biotic stimulus GO:0009607 101 0.021
Worm
macromolecule modification GO:0043412 218 0.020
digestive tract development GO:0048565 122 0.020
macromolecular complex assembly GO:0065003 193 0.020
response to abiotic stimulus GO:0009628 152 0.020
membrane invagination GO:0010324 98 0.020
anatomical structure formation involved in morphogenesis GO:0048646 250 0.020
regulation of gene expression epigenetic GO:0040029 163 0.020
regulation of multicellular organismal development GO:2000026 317 0.019
cellular protein metabolic process GO:0044267 279 0.019
defense response to bacterium GO:0042742 86 0.019
Worm
epithelial tube morphogenesis GO:0060562 1 0.019
positive regulation of macromolecule metabolic process GO:0010604 149 0.019
Yeast Worm
lipid oxidation GO:0034440 1 0.019
positive regulation of stem cell differentiation GO:2000738 1 0.019
striated muscle myosin thick filament assembly GO:0071688 138 0.018
negative regulation of gene expression GO:0010629 217 0.018
cell cell signaling GO:0007267 118 0.018
cellular component movement GO:0006928 388 0.018
Worm
phagocytosis engulfment GO:0006911 98 0.018
neurological system process GO:0050877 53 0.018
establishment of cell polarity GO:0030010 46 0.018
catabolic process GO:0009056 318 0.018
oocyte construction GO:0007308 2 0.017
sensory organ morphogenesis GO:0090596 2 0.017
epithelium development GO:0060429 68 0.017
cuticle development GO:0042335 100 0.017
establishment of spindle orientation GO:0051294 34 0.017
negative regulation of macromolecule metabolic process GO:0010605 229 0.017
fatty acid oxidation GO:0019395 1 0.017
intracellular protein transmembrane import GO:0044743 3 0.017
enzyme linked receptor protein signaling pathway GO:0007167 50 0.016
regulation of neurogenesis GO:0050767 40 0.016
negative regulation of multicellular organismal process GO:0051241 236 0.016
single organism biosynthetic process GO:0044711 91 0.016
Yeast
response to chemical GO:0042221 356 0.016
Yeast Worm
positive regulation of cell differentiation GO:0045597 8 0.016
synaptic transmission cholinergic GO:0007271 21 0.016
tube development GO:0035295 126 0.016
pattern specification process GO:0007389 59 0.016
carboxylic acid metabolic process GO:0019752 34 0.016
cellular component assembly involved in morphogenesis GO:0010927 183 0.016
cellular lipid metabolic process GO:0044255 40 0.016
single organism organelle organization GO:1902589 501 0.015
phosphorylation GO:0016310 116 0.015
muscle fiber development GO:0048747 2 0.015
cellular protein complex assembly GO:0043623 178 0.015
response to metal ion GO:0010038 33 0.015
Worm
myosin filament organization GO:0031033 138 0.015
signal transduction GO:0007165 317 0.015
immune response GO:0006955 192 0.015
Worm
post embryonic organ development GO:0048569 336 0.015
establishment of vesicle localization GO:0051650 23 0.015
Worm
regulation of transcription dna templated GO:0006355 164 0.014
Yeast Worm
regulation of transport GO:0051049 91 0.014
cellular macromolecule localization GO:0070727 75 0.014
Worm
phagocytosis GO:0006909 115 0.014
response to organic substance GO:0010033 131 0.014
cell growth GO:0016049 44 0.014
establishment of rna localization GO:0051236 3 0.014
vesicle localization GO:0051648 24 0.014
Worm
protein complex biogenesis GO:0070271 186 0.014
cellular amine metabolic process GO:0044106 15 0.014
nervous system development GO:0007399 253 0.014
establishment of spindle localization GO:0051293 51 0.013
peptidyl serine modification GO:0018209 20 0.013
Worm
response to oxygen containing compound GO:1901700 44 0.013
Worm
positive regulation of cell communication GO:0010647 69 0.013
regulation of protein metabolic process GO:0051246 81 0.013
organonitrogen compound metabolic process GO:1901564 151 0.013
peptidyl serine phosphorylation GO:0018105 20 0.013
Worm
bmp signaling pathway GO:0030509 3 0.013
cell division GO:0051301 262 0.013
peptidyl amino acid modification GO:0018193 58 0.012
Worm
head development GO:0060322 1 0.012
regulation of molecular function GO:0065009 89 0.012
positive regulation of transcription from rna polymerase ii promoter in response to osmotic stress GO:0061393 1 0.012
Yeast
regulation of protein stability GO:0031647 3 0.012
monosaccharide metabolic process GO:0005996 2 0.012
positive regulation of protein metabolic process GO:0051247 45 0.012
collagen and cuticulin based cuticle development GO:0040002 99 0.012
regulation of epithelial cell proliferation GO:0050678 1 0.012
amine metabolic process GO:0009308 15 0.012
regulation of protein import into nucleus GO:0042306 3 0.012
organic substance transport GO:0071702 113 0.012
system process GO:0003008 136 0.012
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 2 0.012
Yeast
positive regulation of transcription dna templated GO:0045893 102 0.012
Yeast Worm
regulation of localization GO:0032879 194 0.012
Worm
epithelial cell differentiation GO:0030855 17 0.012
response to heat GO:0009408 50 0.011
Yeast Worm
positive regulation of neurogenesis GO:0050769 4 0.011
molting cycle GO:0042303 281 0.011
regulation of phosphorylation GO:0042325 45 0.011
neurogenesis GO:0022008 236 0.011
wnt signaling pathway GO:0016055 27 0.011
signal transduction by phosphorylation GO:0023014 31 0.011
regulation of cellular amine metabolic process GO:0033238 0 0.011
cell morphogenesis GO:0000902 163 0.011
regulation of nucleocytoplasmic transport GO:0046822 3 0.011
generation of neurons GO:0048699 235 0.011
nucleic acid transport GO:0050657 3 0.011
carbohydrate derivative metabolic process GO:1901135 141 0.010
intracellular signal transduction GO:0035556 96 0.010
energy taxis GO:0009453 3 0.010
regulation of embryonic development GO:0045995 16 0.010
anterior posterior pattern specification GO:0009952 27 0.010
regulation of cell communication GO:0010646 176 0.010
cellular catabolic process GO:0044248 199 0.010
regulation of signaling GO:0023051 172 0.010
cellular response to stress GO:0033554 162 0.010
Yeast Worm
regulation of cellular protein metabolic process GO:0032268 75 0.010

pmk-3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.011