Caenorhabditis elegans

90 known processes

act-2 (CELE_T04C12.5)

Protein ACT-2

act-2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
microvillus organization GO:0032528 1 0.815
Worm
microvillus assembly GO:0030033 1 0.586
Worm
reproductive structure development GO:0048608 850 0.520
gonad development GO:0008406 840 0.486
genitalia development GO:0048806 741 0.426
embryo development ending in birth or egg hatching GO:0009792 2992 0.423
meiotic nuclear division GO:0007126 300 0.422
meiotic cell cycle GO:0051321 335 0.376
development of primary sexual characteristics GO:0045137 840 0.374
tube formation GO:0035148 2 0.366
Worm
cell migration GO:0016477 306 0.355
sex differentiation GO:0007548 909 0.348
inductive cell migration GO:0040039 145 0.327
locomotion GO:0040011 1634 0.303
post embryonic development GO:0009791 2152 0.301
reproductive system development GO:0061458 850 0.295
organelle assembly GO:0070925 214 0.294
programmed cell death GO:0012501 500 0.278
Worm
organ development GO:0048513 1102 0.271
cell motility GO:0048870 313 0.265
localization of cell GO:0051674 313 0.263
cellular component movement GO:0006928 388 0.260
developmental process involved in reproduction GO:0003006 1165 0.254
embryo development GO:0009790 3052 0.231
cell cycle process GO:0022402 482 0.231
vesicle mediated transport GO:0016192 852 0.228
determination of adult lifespan GO:0008340 812 0.221
mitotic cell cycle process GO:1903047 194 0.211
cellular component assembly involved in morphogenesis GO:0010927 183 0.207
cell cycle GO:0007049 526 0.200
endocytosis GO:0006897 819 0.199
cytoskeleton organization GO:0007010 339 0.195
cell development GO:0048468 696 0.191
cell projection organization GO:0030030 231 0.190
Worm
protein complex subunit organization GO:0071822 280 0.189
cellular protein complex assembly GO:0043623 178 0.189
death GO:0016265 547 0.188
Worm
cytokinesis GO:0000910 80 0.187
cell division GO:0051301 262 0.187
macromolecular complex subunit organization GO:0043933 320 0.184
striated muscle cell differentiation GO:0051146 158 0.184
cellular macromolecular complex assembly GO:0034622 184 0.178
actin cytoskeleton organization GO:0030036 184 0.177
striated muscle cell development GO:0055002 157 0.177
muscle structure development GO:0061061 191 0.176
transport GO:0006810 1093 0.170
anatomical structure formation involved in morphogenesis GO:0048646 250 0.165
muscle cell differentiation GO:0042692 171 0.163
cellular component morphogenesis GO:0032989 318 0.163
myofibril assembly GO:0030239 154 0.141
growth GO:0040007 562 0.140
apoptotic process GO:0006915 478 0.137
Worm
organelle fission GO:0048285 363 0.136
cellular component biogenesis GO:0044085 297 0.135
hermaphrodite genitalia development GO:0040035 734 0.131
protein complex assembly GO:0006461 186 0.128
multicellular organismal aging GO:0010259 812 0.123
protein complex biogenesis GO:0070271 186 0.119
actomyosin structure organization GO:0031032 154 0.108
establishment of localization GO:0051234 1171 0.102
striated muscle myosin thick filament assembly GO:0071688 138 0.101
macromolecular complex assembly GO:0065003 193 0.098
actin filament based process GO:0030029 191 0.096
myosin filament assembly GO:0031034 138 0.095
cell death GO:0008219 547 0.094
Worm
tube development GO:0035295 126 0.092
Worm
aging GO:0007568 812 0.091
receptor mediated endocytosis GO:0006898 715 0.091
cellular component assembly GO:0022607 293 0.089
organelle organization GO:0006996 783 0.086
single organism organelle organization GO:1902589 501 0.086
muscle organ development GO:0007517 26 0.079
Worm
macromolecule localization GO:0033036 771 0.074
regulation of biological quality GO:0065008 741 0.071
lipid storage GO:0019915 565 0.068
single organism reproductive process GO:0044702 1196 0.065
maintenance of location GO:0051235 580 0.065
regulation of multicellular organismal process GO:0051239 726 0.062
lipid localization GO:0010876 573 0.062
multicellular organism reproduction GO:0032504 819 0.055
regulation of developmental growth GO:0048638 389 0.052
multi organism reproductive process GO:0044703 867 0.051
multicellular organismal reproductive process GO:0048609 815 0.050
developmental growth GO:0048589 412 0.049
immune response GO:0006955 192 0.048
behavior GO:0007610 527 0.046
single organism transport GO:0044765 447 0.044
positive regulation of multicellular organism growth GO:0040018 352 0.044
multi organism reproductive behavior GO:0044705 387 0.044
regulation of developmental process GO:0050793 684 0.043
protein metabolic process GO:0019538 422 0.043
negative regulation of biological process GO:0048519 567 0.042
multicellular organism growth GO:0035264 385 0.041
positive regulation of developmental process GO:0051094 408 0.041
biosynthetic process GO:0009058 323 0.040
head development GO:0060322 1 0.040
regulation of growth GO:0040008 409 0.039
female gamete generation GO:0007292 254 0.039
muscle cell development GO:0055001 158 0.038
positive regulation of developmental growth GO:0048639 354 0.038
multi organism behavior GO:0051705 389 0.038
sexual reproduction GO:0019953 546 0.038
positive regulation of growth GO:0045927 369 0.038
regulation of multicellular organism growth GO:0040014 373 0.038
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.037
oviposition GO:0018991 364 0.037
gamete generation GO:0007276 461 0.037
negative regulation of macromolecule metabolic process GO:0010605 229 0.036
positive regulation of multicellular organismal process GO:0051240 417 0.035
negative regulation of metabolic process GO:0009892 240 0.035
multicellular organismal reproductive behavior GO:0033057 384 0.035
response to wounding GO:0009611 4 0.035
regulation of metabolic process GO:0019222 478 0.035
molting cycle GO:0042303 281 0.035
cytokinetic cell separation GO:0000920 5 0.034
innate immune response GO:0045087 190 0.034
regulation of macromolecule metabolic process GO:0060255 421 0.032
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.032
single organism localization GO:1902578 518 0.031
small molecule metabolic process GO:0044281 186 0.031
neurogenesis GO:0022008 236 0.030
reproductive behavior GO:0019098 387 0.030
post embryonic organ development GO:0048569 336 0.030
multi multicellular organism process GO:0044706 390 0.030
generation of neurons GO:0048699 235 0.029
oxoacid metabolic process GO:0043436 47 0.029
defense response GO:0006952 296 0.029
germ cell development GO:0007281 351 0.028
organonitrogen compound metabolic process GO:1901564 151 0.027
regulation of post embryonic development GO:0048580 260 0.027
vulval development GO:0040025 333 0.026
regulation of gene expression GO:0010468 366 0.026
meiotic cell cycle process GO:1903046 170 0.026
microtubule based process GO:0007017 182 0.025
oogenesis GO:0048477 229 0.025
gene expression GO:0010467 412 0.025
nervous system development GO:0007399 253 0.025
cellular localization GO:0051641 360 0.025
negative regulation of multicellular organismal process GO:0051241 236 0.025
neuron projection morphogenesis GO:0048812 114 0.025
body morphogenesis GO:0010171 620 0.024
phosphorus metabolic process GO:0006793 232 0.024
carboxylic acid metabolic process GO:0019752 34 0.024
secretion GO:0046903 147 0.024
regulation of nematode larval development GO:0061062 260 0.024
nucleobase containing compound metabolic process GO:0006139 406 0.023
myosin filament organization GO:0031033 138 0.023
neuron differentiation GO:0030182 217 0.022
cellular protein modification process GO:0006464 207 0.022
organic acid metabolic process GO:0006082 47 0.022
neuron projection development GO:0031175 187 0.022
gene silencing GO:0016458 143 0.021
negative regulation of cellular process GO:0048523 239 0.021
regulation of vulval development GO:0040028 248 0.021
cell projection assembly GO:0030031 35 0.021
Worm
gene silencing by rna GO:0031047 143 0.021
cellular protein metabolic process GO:0044267 279 0.021
regulation of primary metabolic process GO:0080090 292 0.021
secretion by cell GO:0032940 138 0.021
response to external stimulus GO:0009605 289 0.021
negative regulation of nematode larval development GO:0061064 208 0.020
organic substance biosynthetic process GO:1901576 323 0.020
response to chemical GO:0042221 356 0.020
protein modification process GO:0036211 207 0.020
regulation of biosynthetic process GO:0009889 189 0.020
signaling GO:0023052 401 0.020
response to other organism GO:0051707 101 0.020
macromolecule modification GO:0043412 218 0.019
negative regulation of developmental process GO:0051093 227 0.019
cell projection morphogenesis GO:0048858 148 0.019
regulation of cellular component organization GO:0051128 248 0.019
regulation of signal transduction GO:0009966 135 0.019
rna metabolic process GO:0016070 228 0.019
negative regulation of gene expression GO:0010629 217 0.019
regulation of cellular ketone metabolic process GO:0010565 3 0.019
nucleic acid metabolic process GO:0090304 299 0.018
catabolic process GO:0009056 318 0.018
regulation of behavior GO:0050795 97 0.018
neuron development GO:0048666 199 0.018
posttranscriptional gene silencing GO:0016441 143 0.018
regulation of cellular amine metabolic process GO:0033238 0 0.017
cellular amine metabolic process GO:0044106 15 0.017
posttranscriptional regulation of gene expression GO:0010608 166 0.017
regulation of gene expression epigenetic GO:0040029 163 0.017
signal transduction GO:0007165 317 0.017
adult behavior GO:0030534 3 0.017
nucleobase containing compound biosynthetic process GO:0034654 184 0.017
mitotic spindle organization GO:0007052 81 0.017
regulation of response to stimulus GO:0048583 243 0.017
defense response to other organism GO:0098542 100 0.016
negative regulation of vulval development GO:0040027 206 0.016
establishment of localization in cell GO:0051649 318 0.016
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.016
protein localization GO:0008104 205 0.016
embryonic morphogenesis GO:0048598 152 0.016
ribonucleoprotein complex assembly GO:0022618 4 0.016
meiotic chromosome segregation GO:0045132 139 0.016
response to external biotic stimulus GO:0043207 101 0.016
muscle tissue development GO:0060537 1 0.015
male sex differentiation GO:0046661 86 0.015
cellular biosynthetic process GO:0044249 315 0.015
synaptic transmission GO:0007268 106 0.015
regulation of phosphorus metabolic process GO:0051174 81 0.015
positive regulation of neurogenesis GO:0050769 4 0.015
regulation of localization GO:0032879 194 0.015
organic substance catabolic process GO:1901575 294 0.015
chromosome segregation GO:0007059 180 0.015
response to bacterium GO:0009617 86 0.015
organic cyclic compound catabolic process GO:1901361 119 0.015
rna interference GO:0016246 137 0.015
heterocycle catabolic process GO:0046700 119 0.015
nucleobase containing compound catabolic process GO:0034655 114 0.015
regulation of cellular amino acid metabolic process GO:0006521 0 0.015
neuromuscular junction development GO:0007528 2 0.014
amine metabolic process GO:0009308 15 0.014
protein catabolic process GO:0030163 162 0.014
negative regulation of post embryonic development GO:0048581 208 0.014
regulation of nucleocytoplasmic transport GO:0046822 3 0.014
carbohydrate derivative metabolic process GO:1901135 141 0.014
peptidyl tyrosine phosphorylation GO:0018108 2 0.014
posttranscriptional gene silencing by rna GO:0035194 143 0.014
aromatic compound biosynthetic process GO:0019438 192 0.014
single organism signaling GO:0044700 401 0.014
chemotaxis GO:0006935 120 0.014
cellular amino acid metabolic process GO:0006520 15 0.014
axon development GO:0061564 163 0.014
macromolecule catabolic process GO:0009057 202 0.013
collagen and cuticulin based cuticle development GO:0040002 99 0.013
transcription dna templated GO:0006351 168 0.013
phagocytosis GO:0006909 115 0.013
regulation of cellular metabolic process GO:0031323 305 0.013
memory GO:0007613 3 0.013
regulation of signaling GO:0023051 172 0.013
regulation of macromolecule biosynthetic process GO:0010556 189 0.013
protein oligomerization GO:0051259 4 0.013
negative regulation of gene expression epigenetic GO:0045814 2 0.013
regulation of apoptotic signaling pathway GO:2001233 1 0.013
regulation of lipid metabolic process GO:0019216 4 0.013
cellular ketone metabolic process GO:0042180 14 0.013
nucleotide metabolic process GO:0009117 108 0.013
negative regulation of signal transduction GO:0009968 60 0.013
response to biotic stimulus GO:0009607 101 0.013
regulation of organelle organization GO:0033043 164 0.013
organic substance transport GO:0071702 113 0.013
ras protein signal transduction GO:0007265 31 0.013
defense response to bacterium GO:0042742 86 0.013
ribosome biogenesis GO:0042254 4 0.012
regulation of nitrogen compound metabolic process GO:0051171 222 0.012
cellular response to stress GO:0033554 162 0.012
heterocycle biosynthetic process GO:0018130 187 0.012
cellular nitrogen compound catabolic process GO:0044270 119 0.012
organic cyclic compound biosynthetic process GO:1901362 195 0.012
transcription from rna polymerase ii promoter GO:0006366 149 0.012
regulation of cellular biosynthetic process GO:0031326 189 0.012
nematode male tail tip morphogenesis GO:0045138 77 0.012
adult locomotory behavior GO:0008344 1 0.012
regulation of multicellular organismal development GO:2000026 317 0.012
single organism biosynthetic process GO:0044711 91 0.012
neuron recognition GO:0008038 83 0.012
cell type specific apoptotic process GO:0097285 4 0.012
regulation of protein metabolic process GO:0051246 81 0.012
cell morphogenesis GO:0000902 163 0.012
regulation of rna biosynthetic process GO:2001141 165 0.012
male anatomical structure morphogenesis GO:0090598 78 0.011
membrane invagination GO:0010324 98 0.011
regulation of molecular function GO:0065009 89 0.011
taxis GO:0042330 128 0.011
neurological system process GO:0050877 53 0.011
cell proliferation GO:0008283 116 0.011
response to acid chemical GO:0001101 4 0.011
internal peptidyl lysine acetylation GO:0018393 3 0.011
phosphate containing compound metabolic process GO:0006796 232 0.011
atp metabolic process GO:0046034 42 0.011
response to temperature stimulus GO:0009266 66 0.011
chromatin assembly or disassembly GO:0006333 1 0.011
macromolecule biosynthetic process GO:0009059 250 0.011
chromosome organization GO:0051276 104 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.011
regulation of transcription dna templated GO:0006355 164 0.011
regulation of cell communication GO:0010646 176 0.011
cell recognition GO:0008037 85 0.011
feeding behavior GO:0007631 70 0.011
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 2 0.011
cell cell signaling GO:0007267 118 0.011
positive regulation of cellular process GO:0048522 332 0.011
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.011
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.011
detection of external stimulus GO:0009581 4 0.011
apoptotic cell clearance GO:0043277 111 0.011
sensory organ morphogenesis GO:0090596 2 0.011
regulation of meiotic cell cycle GO:0051445 136 0.011
negative regulation of neurogenesis GO:0050768 4 0.011
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.011
rna biosynthetic process GO:0032774 169 0.010
axonogenesis GO:0007409 102 0.010
glycosyl compound metabolic process GO:1901657 100 0.010
regulation of response to wounding GO:1903034 1 0.010
canonical wnt signaling pathway GO:0060070 3 0.010
negative regulation of biosynthetic process GO:0009890 65 0.010
regulation of epithelial cell differentiation GO:0030856 4 0.010
intracellular signal transduction GO:0035556 96 0.010
regulation of protein targeting GO:1903533 3 0.010
lipid metabolic process GO:0006629 77 0.010
cellular catabolic process GO:0044248 199 0.010
phosphorylation GO:0016310 116 0.010
cellular nitrogen compound biosynthetic process GO:0044271 192 0.010
oxidation reduction process GO:0055114 59 0.010
regulation of cell cycle GO:0051726 194 0.010
nucleobase containing small molecule metabolic process GO:0055086 115 0.010
regulation of cytoplasmic transport GO:1903649 3 0.010
axonal fasciculation GO:0007413 79 0.010

act-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.032
nervous system disease DOID:863 0 0.016