Caenorhabditis elegans

41 known processes

sox-2 (CELE_K08A8.2)

Protein SOX-2

sox-2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cell fate commitment GO:0045165 139 0.362
Mouse
embryo development GO:0009790 3052 0.356
embryo development ending in birth or egg hatching GO:0009792 2992 0.338
locomotion GO:0040011 1634 0.288
positive regulation of rna biosynthetic process GO:1902680 102 0.262
Mouse Fly
developmental process involved in reproduction GO:0003006 1165 0.257
regulation of multicellular organismal development GO:2000026 317 0.256
Mouse
gamete generation GO:0007276 461 0.243
Mouse
regulation of nitrogen compound metabolic process GO:0051171 222 0.234
Zebrafish Mouse Fly
axonogenesis GO:0007409 102 0.222
Fly
regulation of neuron differentiation GO:0045664 40 0.214
Mouse
programmed cell death GO:0012501 500 0.209
hermaphrodite genitalia development GO:0040035 734 0.208
cell projection organization GO:0030030 231 0.203
Fly
regulation of rna biosynthetic process GO:2001141 165 0.200
Zebrafish Mouse Fly
positive regulation of nucleic acid templated transcription GO:1903508 102 0.198
Mouse Fly
rna metabolic process GO:0016070 228 0.196
Zebrafish Mouse Fly
growth GO:0040007 562 0.182
Zebrafish
single organism reproductive process GO:0044702 1196 0.161
organ development GO:0048513 1102 0.158
head development GO:0060322 1 0.152
Mouse
developmental growth GO:0048589 412 0.150
Zebrafish
neuron projection development GO:0031175 187 0.150
Fly
positive regulation of cellular biosynthetic process GO:0031328 109 0.148
Mouse Fly
positive regulation of neuron differentiation GO:0045666 4 0.146
Mouse
death GO:0016265 547 0.145
localization of cell GO:0051674 313 0.143
reproductive system development GO:0061458 850 0.141
cell motility GO:0048870 313 0.140
heterocycle biosynthetic process GO:0018130 187 0.137
Zebrafish Mouse Fly
post embryonic development GO:0009791 2152 0.137
nucleobase containing compound biosynthetic process GO:0034654 184 0.137
Zebrafish Mouse Fly
endocytosis GO:0006897 819 0.137
positive regulation of growth GO:0045927 369 0.136
apoptotic process GO:0006915 478 0.135
reproductive structure development GO:0048608 850 0.135
regulation of nucleic acid templated transcription GO:1903506 165 0.134
Zebrafish Mouse Fly
neuron differentiation GO:0030182 217 0.133
Zebrafish Mouse Fly
organelle organization GO:0006996 783 0.132
cell morphogenesis involved in differentiation GO:0000904 112 0.130
Fly
transport GO:0006810 1093 0.128
regulation of post embryonic development GO:0048580 260 0.126
multicellular organismal reproductive process GO:0048609 815 0.123
aging GO:0007568 812 0.122
neuron development GO:0048666 199 0.121
Zebrafish Fly
transcription from rna polymerase ii promoter GO:0006366 149 0.120
Mouse Fly
multicellular organism reproduction GO:0032504 819 0.119
cell morphogenesis GO:0000902 163 0.119
Fly
regulation of gene expression GO:0010468 366 0.116
Zebrafish Mouse Fly
behavior GO:0007610 527 0.115
cell projection morphogenesis GO:0048858 148 0.114
Fly
positive regulation of macromolecule metabolic process GO:0010604 149 0.110
Mouse Fly
sensory organ morphogenesis GO:0090596 2 0.110
Zebrafish Mouse
body morphogenesis GO:0010171 620 0.109
cell part morphogenesis GO:0032990 152 0.108
Fly
vesicle mediated transport GO:0016192 852 0.108
regulation of multicellular organismal process GO:0051239 726 0.107
Mouse
determination of adult lifespan GO:0008340 812 0.107
multi multicellular organism process GO:0044706 390 0.107
sex differentiation GO:0007548 909 0.104
positive regulation of transcription dna templated GO:0045893 102 0.104
Mouse Fly
regulation of locomotion GO:0040012 161 0.104
positive regulation of cellular process GO:0048522 332 0.102
Mouse Fly
anatomical structure formation involved in morphogenesis GO:0048646 250 0.101
Zebrafish Mouse
aromatic compound biosynthetic process GO:0019438 192 0.100
Zebrafish Mouse Fly
single organism transport GO:0044765 447 0.098
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.098
Zebrafish Mouse Fly
regulation of transcription dna templated GO:0006355 164 0.097
Zebrafish Mouse Fly
generation of neurons GO:0048699 235 0.097
Zebrafish Mouse Fly
nucleic acid metabolic process GO:0090304 299 0.096
Zebrafish Mouse Fly
cell migration GO:0016477 306 0.096
development of primary sexual characteristics GO:0045137 840 0.093
cellular component morphogenesis GO:0032989 318 0.093
Fly
regulation of developmental growth GO:0048638 389 0.091
gonad development GO:0008406 840 0.091
multicellular organismal reproductive behavior GO:0033057 384 0.090
response to chemical GO:0042221 356 0.090
Mouse Fly
negative regulation of biological process GO:0048519 567 0.090
Mouse
positive regulation of epithelial cell proliferation GO:0050679 1 0.090
positive regulation of multicellular organismal process GO:0051240 417 0.089
Mouse
motor neuron axon guidance GO:0008045 13 0.088
post embryonic organ development GO:0048569 336 0.087
cellular component movement GO:0006928 388 0.085
Fly
multi organism reproductive process GO:0044703 867 0.084
regulation of growth GO:0040008 409 0.084
regulation of rna metabolic process GO:0051252 173 0.083
Zebrafish Mouse Fly
cell development GO:0048468 696 0.083
Zebrafish Mouse Fly
rna biosynthetic process GO:0032774 169 0.083
Zebrafish Mouse Fly
regulation of cell development GO:0060284 49 0.082
Mouse
regulation of nematode larval development GO:0061062 260 0.082
protein complex subunit organization GO:0071822 280 0.081
regulation of nervous system development GO:0051960 41 0.081
Mouse
positive regulation of gene expression GO:0010628 112 0.081
Mouse Fly
positive regulation of neurogenesis GO:0050769 4 0.080
Mouse
tube development GO:0035295 126 0.079
Zebrafish Mouse
vulval development GO:0040025 333 0.079
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.079
Mouse
taxis GO:0042330 128 0.077
Fly
positive regulation of developmental growth GO:0048639 354 0.077
germ cell development GO:0007281 351 0.076
regulation of neurogenesis GO:0050767 40 0.074
Mouse
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.074
Mouse
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.074
Mouse Fly
regulation of organ morphogenesis GO:2000027 4 0.073
actin cytoskeleton organization GO:0030036 184 0.070
neurogenesis GO:0022008 236 0.069
Zebrafish Mouse Fly
cell death GO:0008219 547 0.068
axon development GO:0061564 163 0.067
Fly
positive regulation of developmental process GO:0051094 408 0.067
Mouse
regulation of biosynthetic process GO:0009889 189 0.066
Zebrafish Mouse Fly
neural precursor cell proliferation GO:0061351 9 0.066
Mouse
reproductive behavior GO:0019098 387 0.066
nucleobase containing compound metabolic process GO:0006139 406 0.065
Zebrafish Mouse Fly
regionalization GO:0003002 31 0.065
Zebrafish
regulation of biological quality GO:0065008 741 0.064
regulation of primary metabolic process GO:0080090 292 0.064
Zebrafish Mouse Fly
oogenesis GO:0048477 229 0.063
positive regulation of biosynthetic process GO:0009891 109 0.062
Mouse Fly
gastrulation GO:0007369 58 0.062
Zebrafish
multicellular organismal aging GO:0010259 812 0.061
chemotaxis GO:0006935 120 0.061
Fly
digestive system development GO:0055123 122 0.059
Zebrafish
regulation of cellular biosynthetic process GO:0031326 189 0.059
Zebrafish Mouse Fly
macromolecule localization GO:0033036 771 0.058
regulation of vulval development GO:0040028 248 0.057
establishment of localization GO:0051234 1171 0.056
negative regulation of nucleic acid templated transcription GO:1903507 53 0.055
Mouse
actin filament based process GO:0030029 191 0.055
nervous system development GO:0007399 253 0.054
Zebrafish Mouse Fly
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.054
Zebrafish Mouse Fly
maintenance of location GO:0051235 580 0.054
regulation of cell projection organization GO:0031344 38 0.053
regulation of multicellular organism growth GO:0040014 373 0.053
organic substance biosynthetic process GO:1901576 323 0.053
Zebrafish Mouse Fly
regulation of developmental process GO:0050793 684 0.053
Mouse
positive regulation of multicellular organism growth GO:0040018 352 0.053
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.053
Mouse Fly
sexual reproduction GO:0019953 546 0.052
Mouse
neuron projection guidance GO:0097485 82 0.052
Fly
transcription dna templated GO:0006351 168 0.052
Zebrafish Mouse Fly
multi organism behavior GO:0051705 389 0.051
response to external stimulus GO:0009605 289 0.051
Mouse Fly
lipid storage GO:0019915 565 0.050
female gamete generation GO:0007292 254 0.049
oviposition GO:0018991 364 0.049
lipid localization GO:0010876 573 0.049
signaling GO:0023052 401 0.049
Mouse Fly
cell division GO:0051301 262 0.049
multicellular organism growth GO:0035264 385 0.046
negative regulation of nematode larval development GO:0061064 208 0.046
negative regulation of multicellular organismal process GO:0051241 236 0.046
Mouse
positive regulation of rna metabolic process GO:0051254 103 0.045
Mouse Fly
regulation of cell motility GO:2000145 57 0.045
genitalia development GO:0048806 741 0.044
receptor mediated endocytosis GO:0006898 715 0.044
regulation of cell cycle GO:0051726 194 0.044
regulation of cell division GO:0051302 142 0.044
negative regulation of vulval development GO:0040027 206 0.043
cellular component biogenesis GO:0044085 297 0.043
negative regulation of cellular process GO:0048523 239 0.042
Mouse
negative regulation of gene expression GO:0010629 217 0.042
Mouse
regulation of cellular metabolic process GO:0031323 305 0.042
Zebrafish Mouse Fly
regulation of cell migration GO:0030334 55 0.042
axon guidance GO:0007411 82 0.041
Fly
meiotic nuclear division GO:0007126 300 0.041
cytoskeleton organization GO:0007010 339 0.040
tube morphogenesis GO:0035239 79 0.040
Zebrafish Mouse
meiotic cell cycle GO:0051321 335 0.040
protein metabolic process GO:0019538 422 0.039
gene expression GO:0010467 412 0.038
Zebrafish Mouse Fly
phagocytosis GO:0006909 115 0.038
organic cyclic compound biosynthetic process GO:1901362 195 0.038
Zebrafish Mouse Fly
negative regulation of transcription dna templated GO:0045892 53 0.037
Mouse
regulation of macromolecule metabolic process GO:0060255 421 0.037
Zebrafish Mouse Fly
single organism localization GO:1902578 518 0.036
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.036
Mouse Fly
regulation of metabolic process GO:0019222 478 0.036
Zebrafish Mouse Fly
epithelium development GO:0060429 68 0.035
Zebrafish Mouse
multi organism reproductive behavior GO:0044705 387 0.035
molting cycle GO:0042303 281 0.035
negative regulation of metabolic process GO:0009892 240 0.034
Mouse
protein complex biogenesis GO:0070271 186 0.034
establishment of localization in cell GO:0051649 318 0.033
muscle structure development GO:0061061 191 0.033
developmental growth involved in morphogenesis GO:0060560 37 0.033
myofibril assembly GO:0030239 154 0.032
establishment of spindle localization GO:0051293 51 0.032
regulation of localization GO:0032879 194 0.032
cell type specific apoptotic process GO:0097285 4 0.032
regulation of cell differentiation GO:0045595 81 0.031
Mouse
positive regulation of nematode larval development GO:0061063 54 0.031
digestive tract development GO:0048565 122 0.031
Zebrafish
cell cycle GO:0007049 526 0.031
defense response GO:0006952 296 0.031
synaptic transmission GO:0007268 106 0.031
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.031
negative regulation of macromolecule metabolic process GO:0010605 229 0.030
Mouse
catabolic process GO:0009056 318 0.030
single organism organelle organization GO:1902589 501 0.030
establishment or maintenance of cell polarity GO:0007163 63 0.030
establishment of organelle localization GO:0051656 123 0.030
negative regulation of neurogenesis GO:0050768 4 0.029
Mouse
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.029
Mouse Fly
regulation of protein localization GO:0032880 50 0.029
apoptotic cell clearance GO:0043277 111 0.029
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.029
Mouse
regulation of cellular component movement GO:0051270 62 0.029
macromolecular complex subunit organization GO:0043933 320 0.029
cell cycle process GO:0022402 482 0.028
neuron projection extension GO:1990138 37 0.028
spindle localization GO:0051653 51 0.027
negative regulation of transcription from rna polymerase ii promoter GO:0000122 45 0.027
Mouse
negative regulation of biosynthetic process GO:0009890 65 0.026
Mouse
neuron recognition GO:0008038 83 0.026
biosynthetic process GO:0009058 323 0.026
Zebrafish Mouse Fly
positive regulation of cell projection organization GO:0031346 4 0.026
cellular response to stress GO:0033554 162 0.026
striated muscle cell differentiation GO:0051146 158 0.026
regulation of programmed cell death GO:0043067 50 0.025
regulation of cell cycle process GO:0010564 145 0.025
vesicle organization GO:0016050 15 0.025
embryonic morphogenesis GO:0048598 152 0.025
Zebrafish Mouse
cell recognition GO:0008037 85 0.025
negative regulation of signaling GO:0023057 61 0.025
Mouse
neuroblast proliferation GO:0007405 9 0.025
Mouse
nucleic acid templated transcription GO:0097659 169 0.024
Zebrafish Mouse Fly
cellular component assembly GO:0022607 293 0.024
neuron projection morphogenesis GO:0048812 114 0.024
Fly
cellular protein complex assembly GO:0043623 178 0.024
tissue morphogenesis GO:0048729 65 0.024
Zebrafish Mouse
cellular macromolecular complex assembly GO:0034622 184 0.024
regulation of organelle organization GO:0033043 164 0.024
endoderm development GO:0007492 20 0.024
positive regulation of vulval development GO:0040026 52 0.024
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.023
Fly
synaptic growth at neuromuscular junction GO:0051124 1 0.023
establishment of mitotic spindle localization GO:0040001 41 0.023
regulation of filopodium assembly GO:0051489 2 0.023
macromolecule modification GO:0043412 218 0.023
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.023
Mouse
actomyosin structure organization GO:0031032 154 0.023
cellular response to organic substance GO:0071310 119 0.023
canonical wnt signaling pathway GO:0060070 3 0.023
Mouse
digestive tract morphogenesis GO:0048546 76 0.023
Zebrafish
protein catabolic process GO:0030163 162 0.023
proximal distal pattern formation GO:0009954 6 0.022
epithelial cell proliferation GO:0050673 1 0.022
regulation of neuron projection development GO:0010975 31 0.022
cell fate commitment involved in formation of primary germ layer GO:0060795 33 0.022
positive regulation of cell migration GO:0030335 3 0.022
cellular nitrogen compound biosynthetic process GO:0044271 192 0.022
Zebrafish Mouse Fly
regulation of response to wounding GO:1903034 1 0.022
macromolecule biosynthetic process GO:0009059 250 0.021
Zebrafish Mouse Fly
dendrite development GO:0016358 42 0.021
positive regulation of metabolic process GO:0009893 187 0.021
Mouse Fly
negative regulation of developmental process GO:0051093 227 0.021
Mouse
regeneration GO:0031099 4 0.021
Zebrafish
regulation of cell fate commitment GO:0010453 22 0.021
system process GO:0003008 136 0.021
Mouse
cell proliferation GO:0008283 116 0.021
Mouse
single organism signaling GO:0044700 401 0.020
Mouse Fly
negative regulation of cellular metabolic process GO:0031324 95 0.020
Mouse
chromosome segregation GO:0007059 180 0.020
cellular protein modification process GO:0006464 207 0.020
asymmetric cell division GO:0008356 36 0.020
regulation of epithelial cell proliferation GO:0050678 1 0.020
meiotic cell cycle process GO:1903046 170 0.020
regulation of cell death GO:0010941 65 0.020
positive regulation of signaling GO:0023056 66 0.020
Mouse
meiotic chromosome segregation GO:0045132 139 0.019
organelle assembly GO:0070925 214 0.019
regulation of signaling GO:0023051 172 0.019
Mouse Fly
regulation of anatomical structure morphogenesis GO:0022603 51 0.019
regulation of transport GO:0051049 91 0.019
striated muscle cell development GO:0055002 157 0.019
engulfment of apoptotic cell GO:0043652 94 0.019
cellular component assembly involved in morphogenesis GO:0010927 183 0.019
negative regulation of post embryonic development GO:0048581 208 0.019
regulation of macromolecule biosynthetic process GO:0010556 189 0.019
Zebrafish Mouse Fly
regulation of cytoplasmic transport GO:1903649 3 0.019
protein complex assembly GO:0006461 186 0.019
muscle tissue development GO:0060537 1 0.018
negative regulation of wnt signaling pathway GO:0030178 6 0.018
Mouse
positive regulation of post embryonic development GO:0048582 54 0.018
developmental cell growth GO:0048588 39 0.018
negative regulation of programmed cell death GO:0043069 19 0.018
muscle cell development GO:0055001 158 0.018
phosphorylation GO:0016310 116 0.018
positive regulation of cell morphogenesis involved in differentiation GO:0010770 4 0.018
macromolecular complex assembly GO:0065003 193 0.018
response to external biotic stimulus GO:0043207 101 0.018
pattern specification process GO:0007389 59 0.018
Zebrafish
axon extension GO:0048675 37 0.017
negative regulation of cell communication GO:0010648 61 0.017
Mouse
negative regulation of neuron differentiation GO:0045665 4 0.017
Mouse
cellular localization GO:0051641 360 0.017
positive regulation of cell cycle GO:0045787 55 0.017
protein localization GO:0008104 205 0.017
positive regulation of intracellular transport GO:0032388 2 0.017
chemosensory behavior GO:0007635 33 0.017
positive regulation of neuron projection development GO:0010976 4 0.017
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.016
Zebrafish
myosin filament organization GO:0031033 138 0.016
regulation of meiotic cell cycle GO:0051445 136 0.016
single fertilization GO:0007338 61 0.016
positive regulation of locomotion GO:0040017 42 0.016
membrane invagination GO:0010324 98 0.016
filopodium assembly GO:0046847 2 0.016
regulation of anatomical structure size GO:0090066 46 0.016
regulation of cellular component size GO:0032535 40 0.016
regulation of cellular component biogenesis GO:0044087 26 0.016
neuromuscular junction development GO:0007528 2 0.015
muscle cell differentiation GO:0042692 171 0.015
negative regulation of rna biosynthetic process GO:1902679 53 0.015
Mouse
regulation of cell fate specification GO:0042659 22 0.015
protein modification process GO:0036211 207 0.015
small gtpase mediated signal transduction GO:0007264 32 0.015
regulation of mitotic cell cycle GO:0007346 76 0.015
regulation of apoptotic signaling pathway GO:2001233 1 0.015
organelle fission GO:0048285 363 0.015
cellular protein metabolic process GO:0044267 279 0.015
response to biotic stimulus GO:0009607 101 0.015
positive regulation of jnk cascade GO:0046330 3 0.015
negative regulation of rna metabolic process GO:0051253 53 0.015
Mouse
regulation of cytoskeleton organization GO:0051493 41 0.015
mitotic cell cycle process GO:1903047 194 0.015
regulation of cell size GO:0008361 30 0.015
regulation of phosphorus metabolic process GO:0051174 81 0.015
fertilization GO:0009566 63 0.014
spindle organization GO:0007051 92 0.014
response to other organism GO:0051707 101 0.014
detection of external stimulus GO:0009581 4 0.014
Mouse
cuticle development GO:0042335 100 0.014
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.014
Mouse Fly
cellular response to abiotic stimulus GO:0071214 4 0.014
phagocytosis engulfment GO:0006911 98 0.014
inductive cell migration GO:0040039 145 0.014
regulation of cellular component organization GO:0051128 248 0.014
g1 s transition of mitotic cell cycle GO:0000082 2 0.014
striated muscle myosin thick filament assembly GO:0071688 138 0.014
stem cell proliferation GO:0072089 9 0.013
Mouse
positive regulation of cellular metabolic process GO:0031325 178 0.013
Mouse Fly
response to wounding GO:0009611 4 0.013
Zebrafish
organic substance transport GO:0071702 113 0.013
regulation of phosphorylation GO:0042325 45 0.013
organic substance catabolic process GO:1901575 294 0.013
neuron apoptotic process GO:0051402 4 0.013
lamellipodium assembly GO:0030032 2 0.013
cellular response to chemical stimulus GO:0070887 129 0.013
positive regulation of stress activated mapk cascade GO:0032874 3 0.013
olfactory behavior GO:0042048 27 0.013
microtubule based process GO:0007017 182 0.013
regulation of cell projection assembly GO:0060491 3 0.012
anterior posterior pattern specification GO:0009952 27 0.012
regulation of signal transduction GO:0009966 135 0.012
Mouse Fly
protein phosphorylation GO:0006468 85 0.012
regulation of cellular ketone metabolic process GO:0010565 3 0.012
epithelial tube morphogenesis GO:0060562 1 0.012
Mouse
cellular biosynthetic process GO:0044249 315 0.012
Zebrafish Mouse Fly
myosin filament assembly GO:0031034 138 0.012
regulation of mapk cascade GO:0043408 23 0.012
regulation of cellular amino acid metabolic process GO:0006521 0 0.012
cellular macromolecule catabolic process GO:0044265 73 0.012
chemical homeostasis GO:0048878 29 0.012
tube formation GO:0035148 2 0.011
intracellular signal transduction GO:0035556 96 0.011
collagen and cuticulin based cuticle development GO:0040002 99 0.011
regulation of cell communication GO:0010646 176 0.011
Mouse Fly
secretion GO:0046903 147 0.011
organonitrogen compound metabolic process GO:1901564 151 0.011
regulation of cellular amine metabolic process GO:0033238 0 0.011
cellular macromolecule biosynthetic process GO:0034645 247 0.011
Zebrafish Mouse Fly
specification of axis polarity GO:0065001 13 0.011
negative regulation of signal transduction GO:0009968 60 0.011
Mouse
posttranscriptional regulation of gene expression GO:0010608 166 0.011
synapse organization GO:0050808 24 0.011
homeostatic process GO:0042592 51 0.011
cell cell signaling GO:0007267 118 0.010
Mouse
regulation of nucleocytoplasmic transport GO:0046822 3 0.010
negative regulation of cell death GO:0060548 21 0.010
axonal fasciculation GO:0007413 79 0.010
regulation of protein targeting GO:1903533 3 0.010
regulation of protein metabolic process GO:0051246 81 0.010
actin cytoskeleton reorganization GO:0031532 4 0.010
regulation of cell proliferation GO:0042127 105 0.010
Mouse
negative regulation of response to stimulus GO:0048585 73 0.010
Mouse
nucleus localization GO:0051647 55 0.010
regulation of axonogenesis GO:0050770 24 0.010
protein transport GO:0015031 45 0.010
intracellular transport GO:0046907 77 0.010
cellular macromolecule localization GO:0070727 75 0.010
phosphate containing compound metabolic process GO:0006796 232 0.010

sox-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.035
nervous system disease DOID:863 0 0.016