Caenorhabditis elegans

29 known processes

coh-1 (CELE_K08A8.3)

Protein COH-1

coh-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development GO:0009790 3052 0.183
establishment of localization GO:0051234 1171 0.176
embryo development ending in birth or egg hatching GO:0009792 2992 0.154
locomotion GO:0040011 1634 0.118
post embryonic development GO:0009791 2152 0.100
organelle organization GO:0006996 783 0.099
vesicle mediated transport GO:0016192 852 0.098
receptor mediated endocytosis GO:0006898 715 0.098
determination of adult lifespan GO:0008340 812 0.095
multicellular organismal aging GO:0010259 812 0.095
single organism organelle organization GO:1902589 501 0.093
transport GO:0006810 1093 0.091
endocytosis GO:0006897 819 0.089
macromolecule localization GO:0033036 771 0.089
Human
defense response GO:0006952 296 0.086
cell development GO:0048468 696 0.085
regulation of multicellular organismal process GO:0051239 726 0.079
aging GO:0007568 812 0.079
cellular localization GO:0051641 360 0.077
Human
regulation of biological quality GO:0065008 741 0.075
cell cycle GO:0007049 526 0.075
multi organism reproductive process GO:0044703 867 0.074
cell cycle process GO:0022402 482 0.072
growth GO:0040007 562 0.072
response to external stimulus GO:0009605 289 0.069
single organism localization GO:1902578 518 0.069
single organism transport GO:0044765 447 0.067
multi organism reproductive behavior GO:0044705 387 0.067
regulation of multicellular organismal development GO:2000026 317 0.067
negative regulation of biological process GO:0048519 567 0.067
positive regulation of growth GO:0045927 369 0.067
death GO:0016265 547 0.066
multi multicellular organism process GO:0044706 390 0.066
gonad development GO:0008406 840 0.066
Worm
cellular component biogenesis GO:0044085 297 0.065
single organism reproductive process GO:0044702 1196 0.065
Worm
response to biotic stimulus GO:0009607 101 0.064
organ development GO:0048513 1102 0.063
Worm
cellular component movement GO:0006928 388 0.062
lipid localization GO:0010876 573 0.061
regulation of metabolic process GO:0019222 478 0.061
Human Mouse
maintenance of location GO:0051235 580 0.059
negative regulation of metabolic process GO:0009892 240 0.059
developmental process involved in reproduction GO:0003006 1165 0.058
Worm
regulation of developmental process GO:0050793 684 0.056
lipid storage GO:0019915 565 0.056
cytoskeleton organization GO:0007010 339 0.055
regulation of vulval development GO:0040028 248 0.055
multicellular organismal reproductive process GO:0048609 815 0.055
multicellular organism growth GO:0035264 385 0.053
cell death GO:0008219 547 0.053
nervous system development GO:0007399 253 0.053
negative regulation of macromolecule metabolic process GO:0010605 229 0.052
regulation of gene expression epigenetic GO:0040029 163 0.051
regulation of multicellular organism growth GO:0040014 373 0.051
response to wounding GO:0009611 4 0.051
biosynthetic process GO:0009058 323 0.051
Human Mouse
multi organism behavior GO:0051705 389 0.051
macromolecular complex subunit organization GO:0043933 320 0.050
organelle fission GO:0048285 363 0.049
negative regulation of gene expression GO:0010629 217 0.049
post embryonic organ development GO:0048569 336 0.049
oviposition GO:0018991 364 0.049
cell motility GO:0048870 313 0.049
body morphogenesis GO:0010171 620 0.049
regulation of gene expression GO:0010468 366 0.049
Human Mouse
multicellular organismal reproductive behavior GO:0033057 384 0.048
regulation of macromolecule metabolic process GO:0060255 421 0.048
Human Mouse
regulation of cellular component organization GO:0051128 248 0.048
apoptotic process GO:0006915 478 0.047
response to other organism GO:0051707 101 0.047
gene expression GO:0010467 412 0.046
Human Mouse
regulation of cell cycle GO:0051726 194 0.046
behavior GO:0007610 527 0.046
single organism signaling GO:0044700 401 0.045
signaling GO:0023052 401 0.045
positive regulation of multicellular organism growth GO:0040018 352 0.045
cellular component morphogenesis GO:0032989 318 0.045
cellular component assembly GO:0022607 293 0.045
regulation of growth GO:0040008 409 0.045
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.044
protein complex subunit organization GO:0071822 280 0.044
regulation of developmental growth GO:0048638 389 0.043
localization of cell GO:0051674 313 0.043
positive regulation of developmental process GO:0051094 408 0.042
regulation of post embryonic development GO:0048580 260 0.042
positive regulation of developmental growth GO:0048639 354 0.042
cellular response to stress GO:0033554 162 0.042
programmed cell death GO:0012501 500 0.042
protein metabolic process GO:0019538 422 0.042
cell migration GO:0016477 306 0.042
response to external biotic stimulus GO:0043207 101 0.041
positive regulation of multicellular organismal process GO:0051240 417 0.041
mitotic cell cycle process GO:1903047 194 0.041
regulation of cellular metabolic process GO:0031323 305 0.040
Human Mouse
neurogenesis GO:0022008 236 0.039
reproductive structure development GO:0048608 850 0.039
Worm
positive regulation of cellular process GO:0048522 332 0.039
Mouse
phosphorus metabolic process GO:0006793 232 0.039
molting cycle GO:0042303 281 0.039
generation of neurons GO:0048699 235 0.039
response to chemical GO:0042221 356 0.038
negative regulation of nematode larval development GO:0061064 208 0.038
phosphate containing compound metabolic process GO:0006796 232 0.037
neuron differentiation GO:0030182 217 0.036
establishment of localization in cell GO:0051649 318 0.036
multicellular organism reproduction GO:0032504 819 0.036
reproductive behavior GO:0019098 387 0.036
organic substance biosynthetic process GO:1901576 323 0.036
Human Mouse
regulation of localization GO:0032879 194 0.035
cellular protein metabolic process GO:0044267 279 0.035
heterocycle catabolic process GO:0046700 119 0.035
response to abiotic stimulus GO:0009628 152 0.035
negative regulation of post embryonic development GO:0048581 208 0.034
response to topologically incorrect protein GO:0035966 82 0.034
protein localization GO:0008104 205 0.034
Human
genitalia development GO:0048806 741 0.034
Worm
signal transduction GO:0007165 317 0.034
skeletal muscle organ development GO:0060538 3 0.032
development of primary sexual characteristics GO:0045137 840 0.032
Worm
regulation of cellular biosynthetic process GO:0031326 189 0.032
Human Mouse
cellular response to topologically incorrect protein GO:0035967 76 0.032
cellular biosynthetic process GO:0044249 315 0.032
Human Mouse
cell projection organization GO:0030030 231 0.032
negative regulation of developmental process GO:0051093 227 0.032
posttranscriptional regulation of gene expression GO:0010608 166 0.032
cellular protein modification process GO:0006464 207 0.032
chromosome segregation GO:0007059 180 0.032
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.031
inductive cell migration GO:0040039 145 0.031
vulval development GO:0040025 333 0.031
negative regulation of multicellular organismal process GO:0051241 236 0.031
nucleobase containing compound metabolic process GO:0006139 406 0.031
Human Mouse
membrane organization GO:0061024 135 0.031
regulation of nematode larval development GO:0061062 260 0.030
cell morphogenesis GO:0000902 163 0.030
posttranscriptional gene silencing GO:0016441 143 0.030
catabolic process GO:0009056 318 0.030
defense response to other organism GO:0098542 100 0.030
regulation of locomotion GO:0040012 161 0.030
microtubule based process GO:0007017 182 0.029
negative regulation of vulval development GO:0040027 206 0.029
protein modification process GO:0036211 207 0.029
muscle tissue development GO:0060537 1 0.029
regulation of primary metabolic process GO:0080090 292 0.029
Human Mouse
regulation of cellular ketone metabolic process GO:0010565 3 0.028
regulation of mitotic cell cycle GO:0007346 76 0.028
actin cytoskeleton organization GO:0030036 184 0.028
neuron projection development GO:0031175 187 0.028
organic substance catabolic process GO:1901575 294 0.028
sensory organ morphogenesis GO:0090596 2 0.028
macromolecule modification GO:0043412 218 0.028
response to organic substance GO:0010033 131 0.028
meiotic cell cycle GO:0051321 335 0.027
negative regulation of cellular process GO:0048523 239 0.027
cell division GO:0051301 262 0.027
cellular component assembly involved in morphogenesis GO:0010927 183 0.027
negative regulation of cellular metabolic process GO:0031324 95 0.027
response to unfolded protein GO:0006986 71 0.027
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.027
organelle assembly GO:0070925 214 0.027
macromolecular complex assembly GO:0065003 193 0.026
er nucleus signaling pathway GO:0006984 66 0.026
organelle localization GO:0051640 127 0.026
macromolecule biosynthetic process GO:0009059 250 0.026
Human Mouse
reproductive system development GO:0061458 850 0.026
Worm
negative regulation of cellular biosynthetic process GO:0031327 65 0.026
actin filament based process GO:0030029 191 0.026
protein complex biogenesis GO:0070271 186 0.026
head development GO:0060322 1 0.026
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.026
cellular catabolic process GO:0044248 199 0.026
rna interference GO:0016246 137 0.025
developmental growth GO:0048589 412 0.025
neuron development GO:0048666 199 0.025
organonitrogen compound metabolic process GO:1901564 151 0.025
meiotic nuclear division GO:0007126 300 0.025
establishment of organelle localization GO:0051656 123 0.025
cellular macromolecular complex assembly GO:0034622 184 0.025
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.025
axon development GO:0061564 163 0.025
gene silencing GO:0016458 143 0.024
regulation of cell cycle process GO:0010564 145 0.024
cellular protein complex assembly GO:0043623 178 0.024
muscle structure development GO:0061061 191 0.024
cellular response to organic substance GO:0071310 119 0.023
posttranscriptional gene silencing by rna GO:0035194 143 0.023
cellular response to unfolded protein GO:0034620 71 0.023
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.023
muscle cell development GO:0055001 158 0.023
regulation of response to stimulus GO:0048583 243 0.023
protein complex assembly GO:0006461 186 0.023
response to endoplasmic reticulum stress GO:0034976 71 0.022
heterocycle biosynthetic process GO:0018130 187 0.022
Human Mouse
neuromuscular junction development GO:0007528 2 0.022
cellular response to chemical stimulus GO:0070887 129 0.022
regulation of biosynthetic process GO:0009889 189 0.022
Human Mouse
organic cyclic compound catabolic process GO:1901361 119 0.022
germ cell development GO:0007281 351 0.022
regulation of macromolecule biosynthetic process GO:0010556 189 0.021
Human Mouse
small molecule metabolic process GO:0044281 186 0.021
aromatic compound catabolic process GO:0019439 116 0.021
negative regulation of cell cycle GO:0045786 53 0.021
immune response GO:0006955 192 0.021
cell recognition GO:0008037 85 0.021
response to temperature stimulus GO:0009266 66 0.021
regulation of organelle organization GO:0033043 164 0.021
hermaphrodite genitalia development GO:0040035 734 0.021
Worm
striated muscle cell differentiation GO:0051146 158 0.020
cytokinesis GO:0000910 80 0.020
macromolecule catabolic process GO:0009057 202 0.020
nucleic acid metabolic process GO:0090304 299 0.020
Human Mouse
nucleobase containing compound catabolic process GO:0034655 114 0.019
sexual reproduction GO:0019953 546 0.019
gene silencing by rna GO:0031047 143 0.019
positive regulation of neuron differentiation GO:0045666 4 0.019
tissue development GO:0009888 112 0.019
positive regulation of neurogenesis GO:0050769 4 0.019
defense response to bacterium GO:0042742 86 0.019
negative regulation of biosynthetic process GO:0009890 65 0.019
oogenesis GO:0048477 229 0.019
gamete generation GO:0007276 461 0.019
cellular nitrogen compound catabolic process GO:0044270 119 0.018
response to bacterium GO:0009617 86 0.018
actomyosin structure organization GO:0031032 154 0.018
positive regulation of neuron projection development GO:0010976 4 0.018
innate immune response GO:0045087 190 0.018
single organism catabolic process GO:0044712 129 0.018
regulation of signaling GO:0023051 172 0.018
protein catabolic process GO:0030163 162 0.018
transmembrane transport GO:0055085 110 0.018
mitotic nuclear division GO:0007067 89 0.018
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.017
Human Mouse
myofibril assembly GO:0030239 154 0.017
regulation of apoptotic signaling pathway GO:2001233 1 0.017
female gamete generation GO:0007292 254 0.017
collagen and cuticulin based cuticle development GO:0040002 99 0.017
Worm
rna localization GO:0006403 3 0.017
organic cyclic compound biosynthetic process GO:1901362 195 0.017
Human Mouse
muscle cell differentiation GO:0042692 171 0.017
striated muscle cell development GO:0055002 157 0.016
regulation of phosphorus metabolic process GO:0051174 81 0.016
cell morphogenesis involved in differentiation GO:0000904 112 0.016
regulation of cell differentiation GO:0045595 81 0.016
striated muscle myosin thick filament assembly GO:0071688 138 0.016
ribonucleoprotein complex assembly GO:0022618 4 0.016
regulation of nitrogen compound metabolic process GO:0051171 222 0.016
Human Mouse
response to acid chemical GO:0001101 4 0.016
cell type specific apoptotic process GO:0097285 4 0.016
cellular nitrogen compound biosynthetic process GO:0044271 192 0.016
Human Mouse
defense response to fungus GO:0050832 19 0.016
organic acid metabolic process GO:0006082 47 0.016
cell part morphogenesis GO:0032990 152 0.016
cellular response to abiotic stimulus GO:0071214 4 0.016
regulation of cytoplasmic transport GO:1903649 3 0.016
purine nucleoside metabolic process GO:0042278 92 0.015
cell proliferation GO:0008283 116 0.015
axonogenesis GO:0007409 102 0.015
positive regulation of molecular function GO:0044093 61 0.015
phosphorylation GO:0016310 116 0.015
secretion by cell GO:0032940 138 0.015
regeneration GO:0031099 4 0.015
negative regulation of gene expression epigenetic GO:0045814 2 0.015
g1 s transition of mitotic cell cycle GO:0000082 2 0.015
regulation of cellular amino acid metabolic process GO:0006521 0 0.015
secretion GO:0046903 147 0.015
positive regulation of cell migration GO:0030335 3 0.015
regulation of meiotic cell cycle GO:0051445 136 0.015
sex differentiation GO:0007548 909 0.015
Worm
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.014
positive regulation of macromolecule metabolic process GO:0010604 149 0.014
Mouse
single organism cellular localization GO:1902580 72 0.014
cellular macromolecule biosynthetic process GO:0034645 247 0.014
Human Mouse
meiotic cell cycle process GO:1903046 170 0.014
regulation of rna biosynthetic process GO:2001141 165 0.014
Human Mouse
negative regulation of transcription from rna polymerase ii promoter GO:0000122 45 0.014
cell substrate adhesion GO:0031589 1 0.014
defense response to gram negative bacterium GO:0050829 64 0.014
positive regulation of cell cycle GO:0045787 55 0.014
ribonucleoside triphosphate metabolic process GO:0009199 87 0.014
regulation of cellular amine metabolic process GO:0033238 0 0.014
myosin filament organization GO:0031033 138 0.014
regulation of cell death GO:0010941 65 0.014
dendrite development GO:0016358 42 0.014
muscle fiber development GO:0048747 2 0.013
purine nucleoside triphosphate metabolic process GO:0009144 87 0.013
regulation of molecular function GO:0065009 89 0.013
regulation of lipid metabolic process GO:0019216 4 0.013
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.013
Mouse
positive regulation of post embryonic development GO:0048582 54 0.013
regulation of nucleocytoplasmic transport GO:0046822 3 0.013
positive regulation of intracellular transport GO:0032388 2 0.013
carboxylic acid metabolic process GO:0019752 34 0.013
myosin filament assembly GO:0031034 138 0.013
intracellular receptor signaling pathway GO:0030522 2 0.013
nucleic acid templated transcription GO:0097659 169 0.013
Human Mouse
amine metabolic process GO:0009308 15 0.013
cellular macromolecule localization GO:0070727 75 0.013
Human
engulfment of apoptotic cell GO:0043652 94 0.013
membrane invagination GO:0010324 98 0.013
cellular macromolecule catabolic process GO:0044265 73 0.013
rna biosynthetic process GO:0032774 169 0.013
Human Mouse
peptidyl tyrosine phosphorylation GO:0018108 2 0.013
chromatin assembly or disassembly GO:0006333 1 0.013
regulation of cell migration GO:0030334 55 0.013
response to heat GO:0009408 50 0.013
chromosome organization GO:0051276 104 0.013
carbohydrate derivative metabolic process GO:1901135 141 0.013
regulation of protein metabolic process GO:0051246 81 0.013
cellular amine metabolic process GO:0044106 15 0.013
phagocytosis engulfment GO:0006911 98 0.012
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.012
protein oligomerization GO:0051259 4 0.012
regulation of synapse assembly GO:0051963 2 0.012
purine nucleotide metabolic process GO:0006163 95 0.012
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.012
Human Mouse
anatomical structure formation involved in morphogenesis GO:0048646 250 0.012
positive regulation of cell projection organization GO:0031346 4 0.012
apoptotic cell clearance GO:0043277 111 0.012
transcription dna templated GO:0006351 168 0.012
Human Mouse
cell cycle phase transition GO:0044770 19 0.012
phagocytosis GO:0006909 115 0.012
axon extension GO:0048675 37 0.012
cell surface receptor signaling pathway GO:0007166 149 0.012
endoplasmic reticulum unfolded protein response GO:0030968 66 0.012
regulation of cellular component movement GO:0051270 62 0.012
developmental growth involved in morphogenesis GO:0060560 37 0.012
regulation of response to wounding GO:1903034 1 0.012
cellular protein localization GO:0034613 75 0.012
Human
neuron recognition GO:0008038 83 0.012
intracellular signal transduction GO:0035556 96 0.012
cell cycle switching mitotic to meiotic cell cycle GO:0051728 35 0.012
regulation of organ morphogenesis GO:2000027 4 0.012
spindle organization GO:0007051 92 0.012
spindle localization GO:0051653 51 0.012
rna metabolic process GO:0016070 228 0.012
Human Mouse
positive regulation of protein transport GO:0051222 4 0.012
cell cycle g1 s phase transition GO:0044843 2 0.012
system process GO:0003008 136 0.012
ribosome biogenesis GO:0042254 4 0.012
regulation of cell division GO:0051302 142 0.011
cellular amino acid metabolic process GO:0006520 15 0.011
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.011
Mouse
axonal fasciculation GO:0007413 79 0.011
epithelium development GO:0060429 68 0.011
regulation of cell proliferation GO:0042127 105 0.011
cellular ketone metabolic process GO:0042180 14 0.011
organ morphogenesis GO:0009887 67 0.011
positive regulation of vulval development GO:0040026 52 0.011
organophosphate metabolic process GO:0019637 125 0.011
positive regulation of cell communication GO:0010647 69 0.011
regulation of cell projection assembly GO:0060491 3 0.011
regulation of epithelial cell differentiation GO:0030856 4 0.011
chemotaxis GO:0006935 120 0.011
protein phosphorylation GO:0006468 85 0.011
purine nucleoside triphosphate catabolic process GO:0009146 72 0.011
oocyte axis specification GO:0007309 2 0.011
negative regulation of rna metabolic process GO:0051253 53 0.011
aromatic compound biosynthetic process GO:0019438 192 0.011
Human Mouse
establishment or maintenance of cell polarity GO:0007163 63 0.011
regulation of nuclear division GO:0051783 115 0.010
positive regulation of phosphate metabolic process GO:0045937 56 0.010
positive regulation of nematode larval development GO:0061063 54 0.010
muscle organ development GO:0007517 26 0.010
regulation of cellular protein metabolic process GO:0032268 75 0.010
cell fate commitment GO:0045165 139 0.010
negative regulation of transcription dna templated GO:0045892 53 0.010

coh-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.024
nervous system disease DOID:863 0 0.016
cancer DOID:162 0 0.010
disease of cellular proliferation DOID:14566 0 0.010
organ system cancer DOID:0050686 0 0.010