Caenorhabditis elegans

28 known processes

pam-1 (CELE_F49E8.3)

Protein PAM-1

pam-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development ending in birth or egg hatching GO:0009792 2992 0.552
developmental process involved in reproduction GO:0003006 1165 0.239
multicellular organism reproduction GO:0032504 819 0.235
multicellular organismal reproductive process GO:0048609 815 0.223
cell death GO:0008219 547 0.222
receptor mediated endocytosis GO:0006898 715 0.217
organ development GO:0048513 1102 0.216
post embryonic development GO:0009791 2152 0.205
gamete generation GO:0007276 461 0.199
gonad development GO:0008406 840 0.184
establishment of localization GO:0051234 1171 0.184
Worm
phosphate containing compound metabolic process GO:0006796 232 0.147
macromolecule localization GO:0033036 771 0.144
death GO:0016265 547 0.136
growth GO:0040007 562 0.136
cellular macromolecule biosynthetic process GO:0034645 247 0.135
regulation of biological quality GO:0065008 741 0.127
locomotion GO:0040011 1634 0.125
Worm
apoptotic process GO:0006915 478 0.124
reproductive system development GO:0061458 850 0.123
response to external stimulus GO:0009605 289 0.122
phosphorus metabolic process GO:0006793 232 0.116
single organism reproductive process GO:0044702 1196 0.114
Worm
multi organism reproductive process GO:0044703 867 0.114
Worm
single organism localization GO:1902578 518 0.112
establishment of localization in cell GO:0051649 318 0.112
Worm
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.108
response to organic substance GO:0010033 131 0.106
developmental growth GO:0048589 412 0.104
organic substance biosynthetic process GO:1901576 323 0.102
cell development GO:0048468 696 0.102
regulation of macromolecule biosynthetic process GO:0010556 189 0.101
molting cycle GO:0042303 281 0.100
biosynthetic process GO:0009058 323 0.100
response to chemical GO:0042221 356 0.098
Human
embryo development GO:0009790 3052 0.096
genitalia development GO:0048806 741 0.096
catabolic process GO:0009056 318 0.094
programmed cell death GO:0012501 500 0.092
rna metabolic process GO:0016070 228 0.088
regulation of biosynthetic process GO:0009889 189 0.087
determination of adult lifespan GO:0008340 812 0.087
lipid localization GO:0010876 573 0.085
nucleic acid metabolic process GO:0090304 299 0.083
signaling GO:0023052 401 0.082
transport GO:0006810 1093 0.080
sexual reproduction GO:0019953 546 0.079
Worm
maintenance of location GO:0051235 580 0.079
regulation of localization GO:0032879 194 0.078
aging GO:0007568 812 0.077
reproductive structure development GO:0048608 850 0.076
positive regulation of developmental process GO:0051094 408 0.075
response to wounding GO:0009611 4 0.072
cellular catabolic process GO:0044248 199 0.072
regulation of growth GO:0040008 409 0.071
multicellular organismal aging GO:0010259 812 0.070
regulation of multicellular organismal process GO:0051239 726 0.070
sex differentiation GO:0007548 909 0.069
cellular biosynthetic process GO:0044249 315 0.069
lipid storage GO:0019915 565 0.069
germ cell development GO:0007281 351 0.069
hermaphrodite genitalia development GO:0040035 734 0.067
endocytosis GO:0006897 819 0.067
development of primary sexual characteristics GO:0045137 840 0.066
protein localization to endoplasmic reticulum GO:0070972 2 0.065
organelle organization GO:0006996 783 0.064
cellular response to chemical stimulus GO:0070887 129 0.064
Human
single organism catabolic process GO:0044712 129 0.064
regulation of macromolecule metabolic process GO:0060255 421 0.064
signal transduction GO:0007165 317 0.064
positive regulation of multicellular organismal process GO:0051240 417 0.063
single organism transport GO:0044765 447 0.063
organophosphate metabolic process GO:0019637 125 0.063
positive regulation of growth GO:0045927 369 0.062
regulation of cellular metabolic process GO:0031323 305 0.062
macromolecule biosynthetic process GO:0009059 250 0.061
vesicle mediated transport GO:0016192 852 0.061
regulation of metabolic process GO:0019222 478 0.060
multicellular organismal reproductive behavior GO:0033057 384 0.060
reproductive behavior GO:0019098 387 0.059
cellular component assembly GO:0022607 293 0.058
nucleobase containing compound biosynthetic process GO:0034654 184 0.057
regulation of developmental process GO:0050793 684 0.057
positive regulation of cellular process GO:0048522 332 0.057
cellular response to stress GO:0033554 162 0.057
Human
protein localization GO:0008104 205 0.056
oviposition GO:0018991 364 0.055
body morphogenesis GO:0010171 620 0.055
Worm
macromolecular complex subunit organization GO:0043933 320 0.055
cellular component biogenesis GO:0044085 297 0.054
macromolecule catabolic process GO:0009057 202 0.054
behavior GO:0007610 527 0.053
positive regulation of multicellular organism growth GO:0040018 352 0.052
regulation of cellular biosynthetic process GO:0031326 189 0.051
organic cyclic compound biosynthetic process GO:1901362 195 0.051
cell motility GO:0048870 313 0.051
multi organism reproductive behavior GO:0044705 387 0.050
female gamete generation GO:0007292 254 0.050
regulation of gene expression GO:0010468 366 0.049
multi organism behavior GO:0051705 389 0.049
macromolecular complex assembly GO:0065003 193 0.049
axon development GO:0061564 163 0.048
heterocycle biosynthetic process GO:0018130 187 0.048
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.047
regulation of developmental growth GO:0048638 389 0.046
organelle fission GO:0048285 363 0.045
oocyte construction GO:0007308 2 0.044
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.043
small molecule metabolic process GO:0044281 186 0.042
cellular response to unfolded protein GO:0034620 71 0.041
nucleoside metabolic process GO:0009116 99 0.041
nucleobase containing compound metabolic process GO:0006139 406 0.041
response to endoplasmic reticulum stress GO:0034976 71 0.039
regulation of primary metabolic process GO:0080090 292 0.038
regulation of multicellular organism growth GO:0040014 373 0.038
regulation of rna metabolic process GO:0051252 173 0.038
positive regulation of developmental growth GO:0048639 354 0.037
anatomical structure formation involved in morphogenesis GO:0048646 250 0.036
microtubule based process GO:0007017 182 0.036
response to other organism GO:0051707 101 0.036
mitotic nuclear division GO:0007067 89 0.035
localization of cell GO:0051674 313 0.035
organic substance catabolic process GO:1901575 294 0.035
cell cycle process GO:0022402 482 0.035
meiotic nuclear division GO:0007126 300 0.035
mitotic spindle organization GO:0007052 81 0.034
regulation of protein localization GO:0032880 50 0.034
carboxylic acid metabolic process GO:0019752 34 0.034
regulation of cellular component organization GO:0051128 248 0.033
neuron development GO:0048666 199 0.032
secretion by cell GO:0032940 138 0.032
ion transport GO:0006811 113 0.032
multicellular organism growth GO:0035264 385 0.031
cellular nitrogen compound biosynthetic process GO:0044271 192 0.031
oxoacid metabolic process GO:0043436 47 0.031
negative regulation of biological process GO:0048519 567 0.031
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.031
cellular localization GO:0051641 360 0.031
Worm
cation transport GO:0006812 78 0.031
regulation of cytoplasmic transport GO:1903649 3 0.030
protein complex subunit organization GO:0071822 280 0.030
transcription dna templated GO:0006351 168 0.029
cell projection organization GO:0030030 231 0.029
rna biosynthetic process GO:0032774 169 0.028
rna localization GO:0006403 3 0.028
aromatic compound biosynthetic process GO:0019438 192 0.028
regulation of multicellular organismal development GO:2000026 317 0.028
immune response GO:0006955 192 0.027
head development GO:0060322 1 0.027
system process GO:0003008 136 0.027
fertilization GO:0009566 63 0.027
Worm
mitotic cell cycle process GO:1903047 194 0.027
neuron projection development GO:0031175 187 0.027
posttranscriptional regulation of gene expression GO:0010608 166 0.027
positive regulation of biosynthetic process GO:0009891 109 0.026
regulation of response to stimulus GO:0048583 243 0.026
regulation of transport GO:0051049 91 0.026
single organism carbohydrate metabolic process GO:0044723 29 0.026
nervous system development GO:0007399 253 0.026
oogenesis GO:0048477 229 0.025
oocyte axis specification GO:0007309 2 0.025
generation of neurons GO:0048699 235 0.024
chromosome segregation GO:0007059 180 0.024
organic acid metabolic process GO:0006082 47 0.024
cellular component movement GO:0006928 388 0.024
cellular response to organic substance GO:0071310 119 0.023
multi multicellular organism process GO:0044706 390 0.023
glycosylation GO:0070085 20 0.023
autophagy GO:0006914 29 0.023
regulation of transcription dna templated GO:0006355 164 0.023
protein catabolic process GO:0030163 162 0.023
cellular protein complex assembly GO:0043623 178 0.023
response to oxygen containing compound GO:1901700 44 0.022
regulation of cellular protein metabolic process GO:0032268 75 0.022
cytoskeleton organization GO:0007010 339 0.022
transcription from rna polymerase ii promoter GO:0006366 149 0.022
nucleobase containing small molecule metabolic process GO:0055086 115 0.021
spermatogenesis GO:0007283 41 0.021
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.021
cellular response to inorganic substance GO:0071241 3 0.021
regulation of multi organism process GO:0043900 69 0.021
ribonucleoprotein complex assembly GO:0022618 4 0.021
response to biotic stimulus GO:0009607 101 0.021
regulation of response to wounding GO:1903034 1 0.021
cell cycle GO:0007049 526 0.021
defense response GO:0006952 296 0.021
lipid metabolic process GO:0006629 77 0.021
posttranscriptional gene silencing GO:0016441 143 0.021
organic substance transport GO:0071702 113 0.020
cell division GO:0051301 262 0.020
neuron differentiation GO:0030182 217 0.020
regulation of rna biosynthetic process GO:2001141 165 0.020
posttranscriptional gene silencing by rna GO:0035194 143 0.020
glycosyl compound catabolic process GO:1901658 79 0.020
carbohydrate metabolic process GO:0005975 34 0.020
cell morphogenesis involved in differentiation GO:0000904 112 0.020
cellular lipid metabolic process GO:0044255 40 0.020
heterocycle catabolic process GO:0046700 119 0.020
protein complex assembly GO:0006461 186 0.019
positive regulation of cellular biosynthetic process GO:0031328 109 0.019
protein complex biogenesis GO:0070271 186 0.019
protein oligomerization GO:0051259 4 0.019
cell migration GO:0016477 306 0.019
regulation of intracellular signal transduction GO:1902531 77 0.019
protein metabolic process GO:0019538 422 0.019
cellular response to metal ion GO:0071248 3 0.018
sensory organ morphogenesis GO:0090596 2 0.018
carbohydrate derivative biosynthetic process GO:1901137 46 0.018
gene expression GO:0010467 412 0.018
positive regulation of rna metabolic process GO:0051254 103 0.018
amine metabolic process GO:0009308 15 0.018
cell projection morphogenesis GO:0048858 148 0.018
gene silencing by rna GO:0031047 143 0.017
regulation of organelle organization GO:0033043 164 0.017
actomyosin structure organization GO:0031032 154 0.017
regulation of nitrogen compound metabolic process GO:0051171 222 0.017
positive regulation of gene expression GO:0010628 112 0.017
single organism membrane fusion GO:0044801 13 0.017
neuron projection morphogenesis GO:0048812 114 0.017
positive regulation of rna biosynthetic process GO:1902680 102 0.017
macromolecule modification GO:0043412 218 0.017
protein modification process GO:0036211 207 0.017
phagocytosis GO:0006909 115 0.017
proteolysis GO:0006508 61 0.017
single organism signaling GO:0044700 401 0.017
rna interference GO:0016246 137 0.016
male gamete generation GO:0048232 41 0.016
atp metabolic process GO:0046034 42 0.016
meiotic cell cycle GO:0051321 335 0.016
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.016
cellular protein metabolic process GO:0044267 279 0.016
regulation of nucleocytoplasmic transport GO:0046822 3 0.015
membrane organization GO:0061024 135 0.015
regulation of nucleic acid templated transcription GO:1903506 165 0.015
cell type specific apoptotic process GO:0097285 4 0.015
spindle organization GO:0007051 92 0.015
apoptotic cell clearance GO:0043277 111 0.015
ribonucleotide metabolic process GO:0009259 99 0.015
regulation of reproductive process GO:2000241 66 0.015
cellular amine metabolic process GO:0044106 15 0.015
organonitrogen compound metabolic process GO:1901564 151 0.015
axonogenesis GO:0007409 102 0.015
cellular macromolecule catabolic process GO:0044265 73 0.015
single organism biosynthetic process GO:0044711 91 0.015
single organism organelle organization GO:1902589 501 0.015
regulation of apoptotic signaling pathway GO:2001233 1 0.015
response to inorganic substance GO:0010035 50 0.015
purine ribonucleoside monophosphate catabolic process GO:0009169 28 0.014
purine nucleoside metabolic process GO:0042278 92 0.014
regulation of locomotion GO:0040012 161 0.014
cellular protein catabolic process GO:0044257 37 0.014
negative regulation of gene expression GO:0010629 217 0.014
actin filament based process GO:0030029 191 0.014
negative regulation of cellular process GO:0048523 239 0.014
neuromuscular junction development GO:0007528 2 0.014
regulation of vesicle mediated transport GO:0060627 27 0.014
ribonucleotide catabolic process GO:0009261 75 0.014
secretion GO:0046903 147 0.014
regulation of apoptotic process GO:0042981 36 0.014
positive regulation of intracellular transport GO:0032388 2 0.014
response to extracellular stimulus GO:0009991 38 0.013
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.013
carbohydrate derivative catabolic process GO:1901136 82 0.013
regulation of protein targeting GO:1903533 3 0.013
defense response to other organism GO:0098542 100 0.013
nucleotide metabolic process GO:0009117 108 0.013
response to external biotic stimulus GO:0043207 101 0.013
cellular nitrogen compound catabolic process GO:0044270 119 0.013
positive regulation of cellular metabolic process GO:0031325 178 0.013
regulation of neurotransmitter levels GO:0001505 36 0.013
positive regulation of metabolic process GO:0009893 187 0.013
nucleoside monophosphate metabolic process GO:0009123 46 0.013
regulation of gene expression epigenetic GO:0040029 163 0.013
sister chromatid segregation GO:0000819 46 0.013
regulation of protein metabolic process GO:0051246 81 0.013
inductive cell migration GO:0040039 145 0.013
cuticle development GO:0042335 100 0.013
endoplasmic reticulum unfolded protein response GO:0030968 66 0.013
phagocytosis engulfment GO:0006911 98 0.013
regulation of protein import into nucleus GO:0042306 3 0.013
establishment of rna localization GO:0051236 3 0.013
carbohydrate biosynthetic process GO:0016051 4 0.013
nucleic acid templated transcription GO:0097659 169 0.013
engulfment of apoptotic cell GO:0043652 94 0.012
nucleobase containing compound catabolic process GO:0034655 114 0.012
membrane invagination GO:0010324 98 0.012
muscle structure development GO:0061061 191 0.012
tissue development GO:0009888 112 0.012
regulation of molecular function GO:0065009 89 0.012
regulation of cellular localization GO:0060341 42 0.012
negative regulation of macromolecule metabolic process GO:0010605 229 0.012
regulation of nuclear division GO:0051783 115 0.012
meiotic cell cycle process GO:1903046 170 0.012
regulation of vulval development GO:0040028 248 0.012
chemotaxis GO:0006935 120 0.012
regulation of oviposition GO:0046662 43 0.012
response to topologically incorrect protein GO:0035966 82 0.012
positive regulation of transcription dna templated GO:0045893 102 0.012
oxidation reduction process GO:0055114 59 0.012
purine ribonucleoside monophosphate metabolic process GO:0009167 43 0.012
positive regulation of nucleic acid templated transcription GO:1903508 102 0.012
organelle disassembly GO:1903008 2 0.012
response to bacterium GO:0009617 86 0.012
dna metabolic process GO:0006259 74 0.011
epithelial tube morphogenesis GO:0060562 1 0.011
lipid biosynthetic process GO:0008610 28 0.011
regeneration GO:0031099 4 0.011
negative regulation of vulval development GO:0040027 206 0.011
cellular amino acid metabolic process GO:0006520 15 0.011
synaptic transmission GO:0007268 106 0.011
establishment of protein localization to membrane GO:0090150 3 0.011
positive regulation of molecular function GO:0044093 61 0.011
cell proliferation GO:0008283 116 0.011
cellular protein modification process GO:0006464 207 0.011
purine containing compound metabolic process GO:0072521 95 0.011
myosin filament organization GO:0031033 138 0.011
purine ribonucleotide catabolic process GO:0009154 75 0.011
intracellular signal transduction GO:0035556 96 0.011
organophosphate catabolic process GO:0046434 81 0.011
regulation of signal transduction GO:0009966 135 0.011
positive regulation of macromolecule metabolic process GO:0010604 149 0.011
establishment of synaptic vesicle localization GO:0097480 21 0.011
nucleoside triphosphate metabolic process GO:0009141 87 0.010
pole plasm assembly GO:0007315 2 0.010
ribonucleoside triphosphate metabolic process GO:0009199 87 0.010
cellular component morphogenesis GO:0032989 318 0.010
positive regulation of innate immune response GO:0045089 4 0.010
regulation of lipid biosynthetic process GO:0046890 1 0.010
ribonucleoside monophosphate metabolic process GO:0009161 45 0.010
positive regulation of protein transport GO:0051222 4 0.010
glutathione metabolic process GO:0006749 2 0.010
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.010
negative regulation of developmental process GO:0051093 227 0.010
regulation of cell death GO:0010941 65 0.010

pam-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.046
nervous system disease DOID:863 0 0.027