Caenorhabditis elegans

101 known processes

xbp-1 (CELE_R74.3)

Protein XBP-1

xbp-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development GO:0009790 3052 0.438
embryo development ending in birth or egg hatching GO:0009792 2992 0.416
locomotion GO:0040011 1634 0.241
regulation of primary metabolic process GO:0080090 292 0.219
organ development GO:0048513 1102 0.208
Human Zebrafish Mouse Fly
regulation of cellular metabolic process GO:0031323 305 0.202
post embryonic development GO:0009791 2152 0.190
regulation of macromolecule metabolic process GO:0060255 421 0.186
vesicle mediated transport GO:0016192 852 0.172
catabolic process GO:0009056 318 0.171
Mouse
programmed cell death GO:0012501 500 0.155
Mouse
cellular component movement GO:0006928 388 0.154
positive regulation of developmental process GO:0051094 408 0.152
Human Mouse
macromolecule catabolic process GO:0009057 202 0.151
Mouse
response to chemical GO:0042221 356 0.149
body morphogenesis GO:0010171 620 0.146
nucleobase containing compound metabolic process GO:0006139 406 0.143
regulation of developmental process GO:0050793 684 0.141
Human Mouse
aging GO:0007568 812 0.134
negative regulation of biological process GO:0048519 567 0.133
Mouse
negative regulation of cellular process GO:0048523 239 0.132
Mouse
response to endoplasmic reticulum stress GO:0034976 71 0.128
nucleic acid metabolic process GO:0090304 299 0.119
establishment of localization GO:0051234 1171 0.116
Mouse
determination of adult lifespan GO:0008340 812 0.116
cellular biosynthetic process GO:0044249 315 0.115
endocytosis GO:0006897 819 0.109
death GO:0016265 547 0.107
Mouse
multicellular organism growth GO:0035264 385 0.101
growth GO:0040007 562 0.096
developmental growth GO:0048589 412 0.095
organelle organization GO:0006996 783 0.094
regulation of gene expression GO:0010468 366 0.093
multicellular organismal aging GO:0010259 812 0.091
single organism localization GO:1902578 518 0.091
Mouse
positive regulation of multicellular organismal process GO:0051240 417 0.090
Human Mouse
cell death GO:0008219 547 0.090
Mouse
organic substance catabolic process GO:1901575 294 0.088
Mouse
single organism signaling GO:0044700 401 0.088
regulation of developmental growth GO:0048638 389 0.084
receptor mediated endocytosis GO:0006898 715 0.083
organic substance biosynthetic process GO:1901576 323 0.082
macromolecule localization GO:0033036 771 0.077
Mouse
regulation of cell death GO:0010941 65 0.074
Mouse
er nucleus signaling pathway GO:0006984 66 0.074
lipid storage GO:0019915 565 0.072
protein metabolic process GO:0019538 422 0.071
Mouse
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.070
establishment of localization in cell GO:0051649 318 0.070
Mouse
regulation of multicellular organismal process GO:0051239 726 0.069
Human Mouse
positive regulation of multicellular organism growth GO:0040018 352 0.068
lipid localization GO:0010876 573 0.067
negative regulation of multicellular organismal process GO:0051241 236 0.067
cellular response to stress GO:0033554 162 0.067
innate immune response GO:0045087 190 0.067
defense response GO:0006952 296 0.067
cell morphogenesis GO:0000902 163 0.066
negative regulation of metabolic process GO:0009892 240 0.064
multi organism reproductive process GO:0044703 867 0.063
cellular macromolecule biosynthetic process GO:0034645 247 0.062
protein complex subunit organization GO:0071822 280 0.061
single organism reproductive process GO:0044702 1196 0.060
maintenance of location GO:0051235 580 0.059
regulation of biological quality GO:0065008 741 0.059
Mouse
positive regulation of developmental growth GO:0048639 354 0.059
regulation of growth GO:0040008 409 0.058
transport GO:0006810 1093 0.058
Mouse
protein modification process GO:0036211 207 0.058
developmental process involved in reproduction GO:0003006 1165 0.057
cell cycle process GO:0022402 482 0.057
positive regulation of metabolic process GO:0009893 187 0.056
negative regulation of gene expression GO:0010629 217 0.055
single organism transport GO:0044765 447 0.055
Mouse
regulation of multicellular organism growth GO:0040014 373 0.055
multicellular organismal reproductive process GO:0048609 815 0.055
regulation of programmed cell death GO:0043067 50 0.055
Mouse
regulation of multicellular organismal development GO:2000026 317 0.054
Human Mouse
cellular localization GO:0051641 360 0.053
Mouse
negative regulation of developmental process GO:0051093 227 0.052
cellular component morphogenesis GO:0032989 318 0.050
multi multicellular organism process GO:0044706 390 0.049
response to external stimulus GO:0009605 289 0.048
Human Mouse
aromatic compound biosynthetic process GO:0019438 192 0.048
regulation of response to stimulus GO:0048583 243 0.048
Human
modification dependent protein catabolic process GO:0019941 32 0.048
multi organism behavior GO:0051705 389 0.047
regulation of vulval development GO:0040028 248 0.047
response to topologically incorrect protein GO:0035966 82 0.046
cellular protein metabolic process GO:0044267 279 0.046
Mouse
membrane organization GO:0061024 135 0.046
macromolecular complex assembly GO:0065003 193 0.046
positive regulation of growth GO:0045927 369 0.045
protein complex assembly GO:0006461 186 0.045
cuticle development GO:0042335 100 0.045
regulation of cell cycle GO:0051726 194 0.041
regulation of nematode larval development GO:0061062 260 0.041
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.041
cellular protein complex assembly GO:0043623 178 0.040
regulation of biosynthetic process GO:0009889 189 0.040
regulation of post embryonic development GO:0048580 260 0.040
positive regulation of biosynthetic process GO:0009891 109 0.039
protein complex biogenesis GO:0070271 186 0.039
immune response GO:0006955 192 0.039
Human
cellular response to topologically incorrect protein GO:0035967 76 0.038
gene expression GO:0010467 412 0.038
signaling GO:0023052 401 0.038
regulation of nitrogen compound metabolic process GO:0051171 222 0.038
regulation of cell communication GO:0010646 176 0.038
Human
apoptotic process GO:0006915 478 0.035
Mouse
vulval development GO:0040025 333 0.035
multi organism reproductive behavior GO:0044705 387 0.035
rna biosynthetic process GO:0032774 169 0.035
regulation of metabolic process GO:0019222 478 0.035
cellular macromolecular complex assembly GO:0034622 184 0.035
oviposition GO:0018991 364 0.034
regulation of protein metabolic process GO:0051246 81 0.034
Mouse
protein localization GO:0008104 205 0.034
Mouse
localization of cell GO:0051674 313 0.034
meiotic cell cycle GO:0051321 335 0.033
multicellular organism reproduction GO:0032504 819 0.033
negative regulation of macromolecule metabolic process GO:0010605 229 0.033
cell division GO:0051301 262 0.033
cell migration GO:0016477 306 0.033
male sex differentiation GO:0046661 86 0.032
regulation of cellular component organization GO:0051128 248 0.032
nucleoside metabolic process GO:0009116 99 0.032
nucleobase containing compound biosynthetic process GO:0034654 184 0.032
single organism organelle organization GO:1902589 501 0.031
phosphorus metabolic process GO:0006793 232 0.031
response to wounding GO:0009611 4 0.031
phosphate containing compound metabolic process GO:0006796 232 0.031
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.030
regulation of cell proliferation GO:0042127 105 0.030
Mouse
chemotaxis GO:0006935 120 0.030
neuron development GO:0048666 199 0.030
anatomical structure formation involved in morphogenesis GO:0048646 250 0.030
response to organic substance GO:0010033 131 0.030
reproductive behavior GO:0019098 387 0.029
regulation of cellular component size GO:0032535 40 0.029
regulation of meiotic cell cycle GO:0051445 136 0.029
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.029
cell part morphogenesis GO:0032990 152 0.028
cellular component assembly GO:0022607 293 0.028
regulation of cell division GO:0051302 142 0.028
cellular component biogenesis GO:0044085 297 0.028
negative regulation of vulval development GO:0040027 206 0.028
macromolecule biosynthetic process GO:0009059 250 0.028
positive regulation of rna biosynthetic process GO:1902680 102 0.028
cellular protein modification process GO:0006464 207 0.027
mapk cascade GO:0000165 31 0.027
organic acid metabolic process GO:0006082 47 0.027
multicellular organismal reproductive behavior GO:0033057 384 0.026
negative regulation of post embryonic development GO:0048581 208 0.026
organic cyclic compound biosynthetic process GO:1901362 195 0.026
establishment of protein localization to membrane GO:0090150 3 0.026
reproductive structure development GO:0048608 850 0.025
transcription dna templated GO:0006351 168 0.025
negative regulation of nematode larval development GO:0061064 208 0.025
positive regulation of macromolecule metabolic process GO:0010604 149 0.025
gamete generation GO:0007276 461 0.025
proteasomal protein catabolic process GO:0010498 20 0.025
Mouse
behavior GO:0007610 527 0.025
axon development GO:0061564 163 0.025
regulation of signal transduction GO:0009966 135 0.024
Human
macromolecular complex subunit organization GO:0043933 320 0.024
cellular catabolic process GO:0044248 199 0.024
Mouse
post embryonic organ development GO:0048569 336 0.024
regulation of organelle organization GO:0033043 164 0.024
actin filament based process GO:0030029 191 0.024
small molecule metabolic process GO:0044281 186 0.024
biosynthetic process GO:0009058 323 0.023
response to other organism GO:0051707 101 0.023
Human Mouse
response to unfolded protein GO:0006986 71 0.023
carbohydrate derivative metabolic process GO:1901135 141 0.023
nucleic acid templated transcription GO:0097659 169 0.022
intracellular transport GO:0046907 77 0.022
regulation of apoptotic process GO:0042981 36 0.022
Mouse
purine nucleoside triphosphate metabolic process GO:0009144 87 0.022
cell development GO:0048468 696 0.022
Mouse
regulation of transcription dna templated GO:0006355 164 0.021
generation of neurons GO:0048699 235 0.021
organic cyclic compound catabolic process GO:1901361 119 0.021
stress activated protein kinase signaling cascade GO:0031098 10 0.021
cell motility GO:0048870 313 0.021
establishment of cell polarity GO:0030010 46 0.021
heterocycle biosynthetic process GO:0018130 187 0.021
positive regulation of epithelial cell proliferation GO:0050679 1 0.021
Mouse
glycosyl compound metabolic process GO:1901657 100 0.021
male anatomical structure morphogenesis GO:0090598 78 0.021
regulation of rna biosynthetic process GO:2001141 165 0.020
ribonucleotide metabolic process GO:0009259 99 0.020
rna metabolic process GO:0016070 228 0.020
sensory organ morphogenesis GO:0090596 2 0.020
regulation of epithelial cell proliferation GO:0050678 1 0.020
Mouse
regulation of apoptotic signaling pathway GO:2001233 1 0.020
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.020
collagen and cuticulin based cuticle development GO:0040002 99 0.020
macromolecule modification GO:0043412 218 0.020
jnk cascade GO:0007254 8 0.019
cellular protein localization GO:0034613 75 0.019
organonitrogen compound metabolic process GO:1901564 151 0.019
female gamete generation GO:0007292 254 0.019
small gtpase mediated signal transduction GO:0007264 32 0.019
single organism catabolic process GO:0044712 129 0.019
ribonucleoside triphosphate metabolic process GO:0009199 87 0.019
organelle assembly GO:0070925 214 0.019
transcription from rna polymerase ii promoter GO:0006366 149 0.019
neuron differentiation GO:0030182 217 0.019
reproductive system development GO:0061458 850 0.019
enzyme linked receptor protein signaling pathway GO:0007167 50 0.019
carboxylic acid metabolic process GO:0019752 34 0.018
sex differentiation GO:0007548 909 0.018
head development GO:0060322 1 0.018
cellular protein catabolic process GO:0044257 37 0.018
Mouse
phagocytosis engulfment GO:0006911 98 0.018
actin cytoskeleton organization GO:0030036 184 0.018
organelle fission GO:0048285 363 0.018
cellular response to chemical stimulus GO:0070887 129 0.017
regulation of cellular response to stress GO:0080135 19 0.017
Human
negative regulation of cell death GO:0060548 21 0.017
Mouse
regulation of molecular function GO:0065009 89 0.017
establishment or maintenance of cell polarity GO:0007163 63 0.017
positive regulation of cellular process GO:0048522 332 0.017
muscle cell development GO:0055001 158 0.017
regulation of catalytic activity GO:0050790 78 0.017
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.017
nucleoside phosphate metabolic process GO:0006753 108 0.017
signal transduction GO:0007165 317 0.017
negative regulation of transcription from rna polymerase ii promoter GO:0000122 45 0.016
protein catabolic process GO:0030163 162 0.016
Mouse
negative regulation of response to stimulus GO:0048585 73 0.016
neuromuscular junction development GO:0007528 2 0.016
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.016
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.016
sexual reproduction GO:0019953 546 0.016
positive regulation of cell migration GO:0030335 3 0.016
nervous system development GO:0007399 253 0.016
purine containing compound metabolic process GO:0072521 95 0.016
response to biotic stimulus GO:0009607 101 0.016
Human Mouse
cellular response to unfolded protein GO:0034620 71 0.016
negative regulation of cellular metabolic process GO:0031324 95 0.016
negative regulation of rna metabolic process GO:0051253 53 0.016
posttranscriptional regulation of gene expression GO:0010608 166 0.016
intracellular signal transduction GO:0035556 96 0.016
positive regulation of gene expression GO:0010628 112 0.016
ribose phosphate metabolic process GO:0019693 99 0.016
tube development GO:0035295 126 0.016
cell projection morphogenesis GO:0048858 148 0.015
purine ribonucleoside metabolic process GO:0046128 92 0.015
regulation of rna metabolic process GO:0051252 173 0.015
muscle structure development GO:0061061 191 0.015
cellular nitrogen compound catabolic process GO:0044270 119 0.015
ribonucleoside triphosphate catabolic process GO:0009203 72 0.015
regulation of cellular catabolic process GO:0031329 51 0.015
Mouse
lipid metabolic process GO:0006629 77 0.015
cellular macromolecule localization GO:0070727 75 0.015
purine nucleoside catabolic process GO:0006152 75 0.015
cytokinesis GO:0000910 80 0.015
neuron projection guidance GO:0097485 82 0.014
response to oxygen containing compound GO:1901700 44 0.014
Human Mouse
stress activated mapk cascade GO:0051403 10 0.014
cellular nitrogen compound biosynthetic process GO:0044271 192 0.014
regulation of reproductive process GO:2000241 66 0.014
negative regulation of cellular biosynthetic process GO:0031327 65 0.014
cell cycle GO:0007049 526 0.014
regulation of cell morphogenesis GO:0022604 40 0.014
synaptic growth at neuromuscular junction GO:0051124 1 0.014
canonical wnt signaling pathway GO:0060070 3 0.014
regulation of cellular biosynthetic process GO:0031326 189 0.014
response to external biotic stimulus GO:0043207 101 0.014
Human Mouse
regulation of lipid metabolic process GO:0019216 4 0.014
epithelial cell proliferation GO:0050673 1 0.014
Mouse
regulation of cellular ketone metabolic process GO:0010565 3 0.014
molting cycle GO:0042303 281 0.014
glycosyl compound catabolic process GO:1901658 79 0.014
regulation of response to stress GO:0080134 28 0.014
Human
regulation of nuclear division GO:0051783 115 0.014
cellular response to organic substance GO:0071310 119 0.013
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.013
gene silencing GO:0016458 143 0.013
negative regulation of rna biosynthetic process GO:1902679 53 0.013
fertilization GO:0009566 63 0.013
positive regulation of cellular metabolic process GO:0031325 178 0.013
striated muscle cell differentiation GO:0051146 158 0.013
chromosome segregation GO:0007059 180 0.013
cell type specific apoptotic process GO:0097285 4 0.013
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 20 0.013
organophosphate metabolic process GO:0019637 125 0.013
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.013
regulation of protein ubiquitination GO:0031396 3 0.013
cytoskeleton organization GO:0007010 339 0.013
cell proliferation GO:0008283 116 0.013
Mouse
myosin filament assembly GO:0031034 138 0.013
negative regulation of apoptotic process GO:0043066 17 0.013
Mouse
meiotic nuclear division GO:0007126 300 0.013
regulation of phosphorus metabolic process GO:0051174 81 0.013
single organism cellular localization GO:1902580 72 0.013
cellular component assembly involved in morphogenesis GO:0010927 183 0.013
defense response to bacterium GO:0042742 86 0.013
nucleobase containing small molecule metabolic process GO:0055086 115 0.013
nucleobase containing compound catabolic process GO:0034655 114 0.012
positive regulation of cellular biosynthetic process GO:0031328 109 0.012
regulation of phosphate metabolic process GO:0019220 81 0.012
neuron projection morphogenesis GO:0048812 114 0.012
regulation of intracellular signal transduction GO:1902531 77 0.012
positive regulation of signal transduction GO:0009967 40 0.012
Human
regulation of signaling GO:0023051 172 0.012
Human
chromosome organization GO:0051276 104 0.012
purine ribonucleoside catabolic process GO:0046130 75 0.012
proteolysis GO:0006508 61 0.012
Mouse
endoplasmic reticulum unfolded protein response GO:0030968 66 0.012
myosin filament organization GO:0031033 138 0.012
regulation of cell differentiation GO:0045595 81 0.012
Human
gene silencing by rna GO:0031047 143 0.012
aromatic compound catabolic process GO:0019439 116 0.012
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.012
cellular amino acid metabolic process GO:0006520 15 0.012
negative regulation of nucleic acid templated transcription GO:1903507 53 0.012
regulation of cellular protein metabolic process GO:0032268 75 0.012
Mouse
positive regulation of cell death GO:0010942 38 0.011
cell morphogenesis involved in differentiation GO:0000904 112 0.011
taxis GO:0042330 128 0.011
nematode male tail tip morphogenesis GO:0045138 77 0.011
axonal fasciculation GO:0007413 79 0.011
regulation of cell migration GO:0030334 55 0.011
digestive tract development GO:0048565 122 0.011
negative regulation of biosynthetic process GO:0009890 65 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.011
gonad development GO:0008406 840 0.011
amine metabolic process GO:0009308 15 0.011
genitalia development GO:0048806 741 0.011
single organism intracellular transport GO:1902582 70 0.011
carbohydrate derivative catabolic process GO:1901136 82 0.011
positive regulation of cell cycle GO:0045787 55 0.011
rna interference GO:0016246 137 0.011
cell cycle switching mitotic to meiotic cell cycle GO:0051728 35 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 32 0.011
Mouse
purine nucleoside triphosphate catabolic process GO:0009146 72 0.011
cell cycle g1 s phase transition GO:0044843 2 0.010
organonitrogen compound catabolic process GO:1901565 90 0.010
cell surface receptor signaling pathway GO:0007166 149 0.010
ribonucleoside metabolic process GO:0009119 98 0.010
purine ribonucleotide metabolic process GO:0009150 95 0.010
axon guidance GO:0007411 82 0.010
g1 s transition of mitotic cell cycle GO:0000082 2 0.010

xbp-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.018
disease of cellular proliferation DOID:14566 0 0.015
disease of anatomical entity DOID:7 0 0.015
cancer DOID:162 0 0.012
organ system cancer DOID:0050686 0 0.012