Caenorhabditis elegans

99 known processes

unc-112 (CELE_C47E8.7)

Protein UNC-112

unc-112 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
actin filament based process GO:0030029 191 0.587
integrin mediated signaling pathway GO:0007229 1 0.572
Human
establishment of localization GO:0051234 1171 0.570
single organism organelle organization GO:1902589 501 0.563
macromolecule catabolic process GO:0009057 202 0.554
striated muscle cell development GO:0055002 157 0.519
skeletal muscle organ development GO:0060538 3 0.504
embryo development GO:0009790 3052 0.496
positive regulation of locomotion GO:0040017 42 0.486
embryonic body morphogenesis GO:0010172 49 0.400
muscle structure development GO:0061061 191 0.399
muscle tissue development GO:0060537 1 0.391
Zebrafish
phosphorus metabolic process GO:0006793 232 0.389
body morphogenesis GO:0010171 620 0.384
phosphate containing compound metabolic process GO:0006796 232 0.371
muscle organ development GO:0007517 26 0.354
axonal defasciculation GO:0007414 1 0.327
single organism localization GO:1902578 518 0.323
muscle system process GO:0003012 43 0.309
response to anesthetic GO:0072347 1 0.306
macromolecular complex subunit organization GO:0043933 320 0.305
muscle contraction GO:0006936 43 0.296
post embryonic development GO:0009791 2152 0.295
transport GO:0006810 1093 0.290
macromolecule localization GO:0033036 771 0.282
Mouse
actin cytoskeleton organization GO:0030036 184 0.281
cell development GO:0048468 696 0.277
protein metabolic process GO:0019538 422 0.265
actomyosin structure organization GO:0031032 154 0.264
striated muscle contraction involved in embryonic body morphogenesis GO:0061199 13 0.264
cytoskeleton organization GO:0007010 339 0.261
cellular localization GO:0051641 360 0.247
Mouse
multicellular organism reproduction GO:0032504 819 0.246
Worm
organelle organization GO:0006996 783 0.239
meiotic cell cycle GO:0051321 335 0.239
vesicle mediated transport GO:0016192 852 0.236
multicellular organismal reproductive process GO:0048609 815 0.220
Worm
organelle assembly GO:0070925 214 0.218
muscle organ morphogenesis GO:0048644 4 0.213
Zebrafish
cellular component morphogenesis GO:0032989 318 0.201
regulation of biological quality GO:0065008 741 0.198
Mouse
protein catabolic process GO:0030163 162 0.197
striated muscle cell differentiation GO:0051146 158 0.191
chemotaxis GO:0006935 120 0.191
cellular protein modification process GO:0006464 207 0.190
multi organism reproductive behavior GO:0044705 387 0.189
positive regulation of cellular process GO:0048522 332 0.184
response to external stimulus GO:0009605 289 0.184
receptor mediated endocytosis GO:0006898 715 0.184
behavior GO:0007610 527 0.183
cellular protein complex assembly GO:0043623 178 0.181
multi organism reproductive process GO:0044703 867 0.174
Worm
muscle cell development GO:0055001 158 0.168
meiotic nuclear division GO:0007126 300 0.167
epithelial tube morphogenesis GO:0060562 1 0.162
establishment of localization in cell GO:0051649 318 0.162
cell surface receptor signaling pathway GO:0007166 149 0.158
Human
nucleotide sugar metabolic process GO:0009225 6 0.157
regulation of developmental process GO:0050793 684 0.156
taxis GO:0042330 128 0.154
single organism signaling GO:0044700 401 0.154
Human
cellular component assembly GO:0022607 293 0.152
single organism transport GO:0044765 447 0.151
organ development GO:0048513 1102 0.148
macromolecular complex assembly GO:0065003 193 0.147
striated muscle contraction GO:0006941 17 0.146
muscle attachment GO:0016203 3 0.145
oviposition GO:0018991 364 0.145
cellular macromolecular complex assembly GO:0034622 184 0.143
cellular protein metabolic process GO:0044267 279 0.137
membrane organization GO:0061024 135 0.134
embryo development ending in birth or egg hatching GO:0009792 2992 0.132
muscle cell differentiation GO:0042692 171 0.132
anatomical structure formation involved in morphogenesis GO:0048646 250 0.126
secretion GO:0046903 147 0.123
organic substance catabolic process GO:1901575 294 0.123
locomotion GO:0040011 1634 0.119
protein complex assembly GO:0006461 186 0.118
multicellular organismal reproductive behavior GO:0033057 384 0.116
protein complex biogenesis GO:0070271 186 0.116
catabolic process GO:0009056 318 0.115
neurogenesis GO:0022008 236 0.109
signaling GO:0023052 401 0.109
Human
regulation of muscle system process GO:0090257 20 0.107
digestive tract morphogenesis GO:0048546 76 0.106
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.105
positive regulation of cell migration GO:0030335 3 0.103
response to chemical GO:0042221 356 0.103
Human
striated muscle myosin thick filament assembly GO:0071688 138 0.101
reproductive behavior GO:0019098 387 0.099
response to abiotic stimulus GO:0009628 152 0.099
macromolecule modification GO:0043412 218 0.098
single organism reproductive process GO:0044702 1196 0.096
Worm
myofibril assembly GO:0030239 154 0.096
organ morphogenesis GO:0009887 67 0.095
Zebrafish
cellular protein localization GO:0034613 75 0.092
Mouse
cellular component movement GO:0006928 388 0.092
positive regulation of signaling GO:0023056 66 0.091
maintenance of location GO:0051235 580 0.090
posttranscriptional regulation of gene expression GO:0010608 166 0.090
cell motility GO:0048870 313 0.089
tube morphogenesis GO:0035239 79 0.089
lipid localization GO:0010876 573 0.088
regulation of localization GO:0032879 194 0.088
protein complex subunit organization GO:0071822 280 0.088
regulation of cell migration GO:0030334 55 0.086
regulation of locomotion GO:0040012 161 0.085
cell morphogenesis GO:0000902 163 0.083
Mouse
multi multicellular organism process GO:0044706 390 0.081
protein modification process GO:0036211 207 0.081
organic substance biosynthetic process GO:1901576 323 0.081
death GO:0016265 547 0.080
cell projection morphogenesis GO:0048858 148 0.079
tube development GO:0035295 126 0.078
bmp signaling pathway GO:0030509 3 0.078
regulation of rna biosynthetic process GO:2001141 165 0.078
signal transduction GO:0007165 317 0.078
Human
phosphorylation GO:0016310 116 0.076
lipid storage GO:0019915 565 0.075
regulation of phosphorus metabolic process GO:0051174 81 0.074
cell cycle GO:0007049 526 0.074
cell part morphogenesis GO:0032990 152 0.072
developmental process involved in reproduction GO:0003006 1165 0.072
Worm
myosin filament assembly GO:0031034 138 0.072
cell death GO:0008219 547 0.071
organophosphate metabolic process GO:0019637 125 0.069
biosynthetic process GO:0009058 323 0.069
genitalia development GO:0048806 741 0.068
Worm
regulation of multicellular organismal process GO:0051239 726 0.067
multicellular organismal aging GO:0010259 812 0.067
secretion by cell GO:0032940 138 0.067
cellular component biogenesis GO:0044085 297 0.067
neuron differentiation GO:0030182 217 0.066
peptidyl amino acid modification GO:0018193 58 0.066
generation of neurons GO:0048699 235 0.066
positive regulation of gene expression GO:0010628 112 0.066
tissue morphogenesis GO:0048729 65 0.065
Zebrafish
regulation of signal transduction GO:0009966 135 0.064
small molecule metabolic process GO:0044281 186 0.063
neuron projection guidance GO:0097485 82 0.063
nervous system development GO:0007399 253 0.063
endocytosis GO:0006897 819 0.063
cell substrate adhesion GO:0031589 1 0.063
cellular component assembly involved in morphogenesis GO:0010927 183 0.063
regulation of cellular component movement GO:0051270 62 0.062
protein localization GO:0008104 205 0.062
Mouse
positive regulation of striated muscle contraction GO:0045989 2 0.062
multi organism behavior GO:0051705 389 0.062
intracellular signal transduction GO:0035556 96 0.061
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.060
response to wounding GO:0009611 4 0.060
Mouse
negative regulation of biological process GO:0048519 567 0.059
cellular macromolecule biosynthetic process GO:0034645 247 0.057
development of primary sexual characteristics GO:0045137 840 0.057
Worm
regulation of cellular metabolic process GO:0031323 305 0.056
aging GO:0007568 812 0.056
system process GO:0003008 136 0.056
regulation of metabolic process GO:0019222 478 0.056
sexual reproduction GO:0019953 546 0.055
Worm
gamete generation GO:0007276 461 0.055
Worm
protein phosphorylation GO:0006468 85 0.054
establishment of protein localization to membrane GO:0090150 3 0.054
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.054
Worm
neuron development GO:0048666 199 0.053
embryonic morphogenesis GO:0048598 152 0.053
regulation of gene expression GO:0010468 366 0.053
cation transport GO:0006812 78 0.052
mesodermal cell migration GO:0008078 9 0.052
organic substance transport GO:0071702 113 0.052
negative regulation of cell communication GO:0010648 61 0.050
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.050
regulation of macromolecule metabolic process GO:0060255 421 0.050
determination of adult lifespan GO:0008340 812 0.050
regulation of vesicle mediated transport GO:0060627 27 0.049
cell cycle process GO:0022402 482 0.049
macromolecule biosynthetic process GO:0009059 250 0.049
establishment of nucleus localization GO:0040023 55 0.049
cellular nitrogen compound biosynthetic process GO:0044271 192 0.048
biological adhesion GO:0022610 21 0.048
cellular biosynthetic process GO:0044249 315 0.048
organelle fission GO:0048285 363 0.047
response to topologically incorrect protein GO:0035966 82 0.047
positive regulation of metabolic process GO:0009893 187 0.046
microtubule based process GO:0007017 182 0.046
apoptotic process GO:0006915 478 0.046
regulation of cellular biosynthetic process GO:0031326 189 0.045
developmental growth GO:0048589 412 0.044
actin filament organization GO:0007015 21 0.044
regulation of actin filament based process GO:0032970 22 0.043
oogenesis GO:0048477 229 0.042
establishment or maintenance of cell polarity GO:0007163 63 0.042
cell matrix adhesion GO:0007160 1 0.042
regulation of cellular component organization GO:0051128 248 0.041
nucleoside phosphate metabolic process GO:0006753 108 0.041
reproductive structure development GO:0048608 850 0.041
Worm
organonitrogen compound metabolic process GO:1901564 151 0.041
cellular amine metabolic process GO:0044106 15 0.041
enzyme linked receptor protein signaling pathway GO:0007167 50 0.041
Human
regulation of signaling GO:0023051 172 0.040
carbohydrate derivative metabolic process GO:1901135 141 0.040
regulation of cell morphogenesis GO:0022604 40 0.039
axonogenesis GO:0007409 102 0.038
epithelium development GO:0060429 68 0.038
cation transmembrane transport GO:0098655 59 0.037
cell junction organization GO:0034330 18 0.037
Mouse
programmed cell death GO:0012501 500 0.036
axon guidance GO:0007411 82 0.036
regulation of cell communication GO:0010646 176 0.035
positive regulation of phosphorus metabolic process GO:0010562 56 0.035
carbohydrate derivative catabolic process GO:1901136 82 0.035
regulation of primary metabolic process GO:0080090 292 0.035
growth GO:0040007 562 0.035
sex differentiation GO:0007548 909 0.034
Worm
regulation of anatomical structure size GO:0090066 46 0.034
multicellular organism growth GO:0035264 385 0.034
positive regulation of nucleic acid templated transcription GO:1903508 102 0.034
dorsal ventral axon guidance GO:0033563 19 0.034
regulation of apoptotic signaling pathway GO:2001233 1 0.033
rna biosynthetic process GO:0032774 169 0.033
regulation of cell motility GO:2000145 57 0.032
ceramide metabolic process GO:0006672 2 0.032
cell adhesion GO:0007155 21 0.032
regulation of developmental growth GO:0048638 389 0.032
sensory organ morphogenesis GO:0090596 2 0.032
engulfment of apoptotic cell GO:0043652 94 0.031
positive regulation of cellular metabolic process GO:0031325 178 0.031
positive regulation of cell communication GO:0010647 69 0.030
regulation of cellular component size GO:0032535 40 0.030
cellular homeostasis GO:0019725 22 0.030
actin filament based movement GO:0030048 4 0.030
regulation of phosphate metabolic process GO:0019220 81 0.029
female meiotic division GO:0007143 17 0.029
reproductive system development GO:0061458 850 0.029
Worm
molting cycle GO:0042303 281 0.029
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.029
positive regulation of growth GO:0045927 369 0.028
ribose phosphate metabolic process GO:0019693 99 0.028
amine metabolic process GO:0009308 15 0.028
hermaphrodite genitalia development GO:0040035 734 0.027
Worm
metal ion transport GO:0030001 49 0.027
positive regulation of response to stimulus GO:0048584 55 0.027
nucleobase containing small molecule metabolic process GO:0055086 115 0.027
digestive system development GO:0055123 122 0.027
regulation of transport GO:0051049 91 0.027
regulation of multicellular organismal development GO:2000026 317 0.027
regulation of biosynthetic process GO:0009889 189 0.026
negative regulation of developmental process GO:0051093 227 0.026
regulation of growth GO:0040008 409 0.026
protein localization to membrane GO:0072657 11 0.026
Mouse
gene expression GO:0010467 412 0.026
regulation of multicellular organism growth GO:0040014 373 0.026
regulation of macromolecule biosynthetic process GO:0010556 189 0.026
regulation of post embryonic development GO:0048580 260 0.025
cell type specific apoptotic process GO:0097285 4 0.025
cell projection organization GO:0030030 231 0.025
positive regulation of phosphate metabolic process GO:0045937 56 0.025
positive regulation of macromolecule metabolic process GO:0010604 149 0.024
neuron projection morphogenesis GO:0048812 114 0.024
calcium mediated signaling GO:0019722 3 0.023
regulation of gene expression epigenetic GO:0040029 163 0.023
single organism membrane organization GO:0044802 35 0.023
Mouse
post embryonic organ development GO:0048569 336 0.023
regulation of anatomical structure morphogenesis GO:0022603 51 0.023
negative regulation of metabolic process GO:0009892 240 0.023
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.022
myosin filament organization GO:0031033 138 0.022
purine nucleotide catabolic process GO:0006195 75 0.022
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.022
axon development GO:0061564 163 0.022
pattern specification process GO:0007389 59 0.022
nucleic acid metabolic process GO:0090304 299 0.022
cell recognition GO:0008037 85 0.022
positive regulation of signal transduction GO:0009967 40 0.021
regulation of endocytosis GO:0030100 25 0.021
nucleobase containing compound biosynthetic process GO:0034654 184 0.021
response to endoplasmic reticulum stress GO:0034976 71 0.021
cellular macromolecule localization GO:0070727 75 0.021
Mouse
positive regulation of cysteine type endopeptidase activity GO:2001056 3 0.021
regulation of molecular function GO:0065009 89 0.021
epithelial cell proliferation GO:0050673 1 0.020
positive regulation of rna metabolic process GO:0051254 103 0.020
negative regulation of cellular process GO:0048523 239 0.020
regulation of nucleic acid templated transcription GO:1903506 165 0.019
actin filament bundle assembly GO:0051017 3 0.019
regulation of nitrogen compound metabolic process GO:0051171 222 0.019
muscle fiber development GO:0048747 2 0.019
regulation of nematode larval development GO:0061062 260 0.019
vulval development GO:0040025 333 0.019
neuron recognition GO:0008038 83 0.019
regulation of cellular amino acid metabolic process GO:0006521 0 0.019
regulation of cellular component biogenesis GO:0044087 26 0.019
protein polymerization GO:0051258 26 0.018
chromosome segregation GO:0007059 180 0.018
nucleic acid templated transcription GO:0097659 169 0.018
cellular ion homeostasis GO:0006873 11 0.018
peptidyl threonine modification GO:0018210 14 0.018
positive regulation of multicellular organismal process GO:0051240 417 0.017
response to organic substance GO:0010033 131 0.017
Human
actin mediated cell contraction GO:0070252 3 0.017
actin cytoskeleton reorganization GO:0031532 4 0.017
regulation of cell cell adhesion GO:0022407 1 0.017
Mouse
rna metabolic process GO:0016070 228 0.017
gene silencing GO:0016458 143 0.017
positive regulation of developmental process GO:0051094 408 0.017
inductive cell migration GO:0040039 145 0.017
regulation of striated muscle contraction GO:0006942 4 0.016
negative regulation of signaling GO:0023057 61 0.016
phagocytosis GO:0006909 115 0.016
positive regulation of cell adhesion GO:0045785 1 0.016
single organismal cell cell adhesion GO:0016337 10 0.016
Mouse
synaptic transmission GO:0007268 106 0.016
cation homeostasis GO:0055080 20 0.016
tissue development GO:0009888 112 0.016
Zebrafish
positive regulation of cell morphogenesis involved in differentiation GO:0010770 4 0.016
ion homeostasis GO:0050801 21 0.016
rna interference GO:0016246 137 0.015
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.015
cellular response to chemical stimulus GO:0070887 129 0.015
Human
positive regulation of catalytic activity GO:0043085 59 0.015
transcription from rna polymerase ii promoter GO:0006366 149 0.015
regulation of cell proliferation GO:0042127 105 0.015
regulation of reproductive process GO:2000241 66 0.015
endodermal cell differentiation GO:0035987 18 0.015
backward locomotion GO:0043057 11 0.015
phagocytosis engulfment GO:0006911 98 0.015
er nucleus signaling pathway GO:0006984 66 0.014
cell cell signaling GO:0007267 118 0.014
positive regulation of biosynthetic process GO:0009891 109 0.014
regulation of synapse assembly GO:0051963 2 0.014
regulation of muscle contraction GO:0006937 20 0.014
posttranscriptional gene silencing GO:0016441 143 0.014
innate immune response GO:0045087 190 0.014
regulation of cell cycle GO:0051726 194 0.014
negative regulation of signal transduction GO:0009968 60 0.014
establishment of protein localization GO:0045184 50 0.014
regulation of cellular ketone metabolic process GO:0010565 3 0.013
regulation of organelle organization GO:0033043 164 0.013
cellular response to stress GO:0033554 162 0.013
gene silencing by rna GO:0031047 143 0.013
meiotic cell cycle process GO:1903046 170 0.013
cellular amino acid metabolic process GO:0006520 15 0.013
transforming growth factor beta receptor signaling pathway GO:0007179 13 0.013
Human
regulation of cell differentiation GO:0045595 81 0.013
cell morphogenesis involved in differentiation GO:0000904 112 0.013
Mouse
response to unfolded protein GO:0006986 71 0.013
regulation of cell death GO:0010941 65 0.013
protein localization to organelle GO:0033365 37 0.013
regulation of system process GO:0044057 27 0.013
carbohydrate metabolic process GO:0005975 34 0.012
neuron projection development GO:0031175 187 0.012
transcription dna templated GO:0006351 168 0.012
somatic muscle development GO:0007525 1 0.012
cellular catabolic process GO:0044248 199 0.012
aromatic compound biosynthetic process GO:0019438 192 0.012
regulation of cellular protein metabolic process GO:0032268 75 0.012
organelle localization GO:0051640 127 0.012
heterocycle biosynthetic process GO:0018130 187 0.012
motor neuron axon guidance GO:0008045 13 0.012
negative regulation of macromolecule metabolic process GO:0010605 229 0.012
divalent metal ion transport GO:0070838 17 0.011
positive regulation of molecular function GO:0044093 61 0.011
regulation of epithelial cell proliferation GO:0050678 1 0.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 12 0.011
carboxylic acid metabolic process GO:0019752 34 0.011
positive regulation of rna biosynthetic process GO:1902680 102 0.011
positive regulation of cellular biosynthetic process GO:0031328 109 0.011
regulation of cell shape GO:0008360 6 0.011
regulation of phagocytosis engulfment GO:0060099 17 0.011
head development GO:0060322 1 0.011
nucleobase containing compound metabolic process GO:0006139 406 0.011
histone h3 k9 methylation GO:0051567 3 0.011
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.011
negative regulation of cellular component organization GO:0051129 33 0.011
nuclear migration GO:0007097 54 0.011
aromatic compound catabolic process GO:0019439 116 0.011
protein localization to basolateral plasma membrane GO:1903361 7 0.011
membrane invagination GO:0010324 98 0.011
regulation of gene silencing GO:0060968 3 0.011
ion transport GO:0006811 113 0.011
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.011
cellular response to hydrogen peroxide GO:0070301 2 0.011
regulation of cellular amine metabolic process GO:0033238 0 0.011
nucleobase containing compound catabolic process GO:0034655 114 0.011
nucleotide metabolic process GO:0009117 108 0.011
localization of cell GO:0051674 313 0.010
sphingolipid metabolic process GO:0006665 2 0.010
nucleoside triphosphate metabolic process GO:0009141 87 0.010
neurological system process GO:0050877 53 0.010

unc-112 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.031
nervous system disease DOID:863 0 0.013
heart disease DOID:114 0 0.012
cardiovascular system disease DOID:1287 0 0.012