Caenorhabditis elegans

63 known processes

thoc-2 (CELE_C16A3.8)

Protein THOC-2

thoc-2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development GO:0009790 3052 0.906
embryo development ending in birth or egg hatching GO:0009792 2992 0.765
single organism organelle organization GO:1902589 501 0.645
cell cycle GO:0007049 526 0.559
chromosome segregation GO:0007059 180 0.545
dna metabolic process GO:0006259 74 0.528
nucleic acid metabolic process GO:0090304 299 0.517
multicellular organism reproduction GO:0032504 819 0.494
regulation of cell cycle GO:0051726 194 0.476
mitotic cell cycle process GO:1903047 194 0.470
multicellular organismal reproductive process GO:0048609 815 0.400
mitotic nuclear division GO:0007067 89 0.396
meiotic nuclear division GO:0007126 300 0.395
cellular component biogenesis GO:0044085 297 0.388
post embryonic development GO:0009791 2152 0.365
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.351
nucleobase containing compound metabolic process GO:0006139 406 0.349
regulation of macromolecule metabolic process GO:0060255 421 0.344
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.335
sex differentiation GO:0007548 909 0.315
apoptotic process GO:0006915 478 0.313
regulation of cellular component organization GO:0051128 248 0.312
regulation of cell division GO:0051302 142 0.297
sexual reproduction GO:0019953 546 0.291
aromatic compound catabolic process GO:0019439 116 0.285
organic substance catabolic process GO:1901575 294 0.284
organelle organization GO:0006996 783 0.263
cell division GO:0051301 262 0.246
cellular component assembly GO:0022607 293 0.239
positive regulation of cellular process GO:0048522 332 0.238
rna metabolic process GO:0016070 228 0.237
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.237
transcription from rna polymerase ii promoter GO:0006366 149 0.231
organelle fission GO:0048285 363 0.215
germ cell development GO:0007281 351 0.213
regulation of nitrogen compound metabolic process GO:0051171 222 0.204
reproductive structure development GO:0048608 850 0.197
positive regulation of transcription dna templated GO:0045893 102 0.192
meiotic cell cycle GO:0051321 335 0.178
regulation of gene expression GO:0010468 366 0.176
oogenesis GO:0048477 229 0.173
cellular catabolic process GO:0044248 199 0.173
positive regulation of cellular metabolic process GO:0031325 178 0.170
protein complex subunit organization GO:0071822 280 0.168
regulation of organelle organization GO:0033043 164 0.159
aromatic compound biosynthetic process GO:0019438 192 0.159
cell motility GO:0048870 313 0.152
single organism localization GO:1902578 518 0.148
Human
negative regulation of biological process GO:0048519 567 0.147
macromolecular complex subunit organization GO:0043933 320 0.139
organic cyclic compound catabolic process GO:1901361 119 0.135
ribonucleoprotein complex assembly GO:0022618 4 0.135
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.133
regulation of biological quality GO:0065008 741 0.131
regulation of rna biosynthetic process GO:2001141 165 0.130
regulation of transcription dna templated GO:0006355 164 0.125
cellular macromolecular complex assembly GO:0034622 184 0.124
positive regulation of biosynthetic process GO:0009891 109 0.124
heterocycle catabolic process GO:0046700 119 0.119
multi organism reproductive process GO:0044703 867 0.119
body morphogenesis GO:0010171 620 0.119
positive regulation of rna metabolic process GO:0051254 103 0.117
cell cycle process GO:0022402 482 0.117
meiotic cell cycle process GO:1903046 170 0.117
nucleobase containing compound catabolic process GO:0034655 114 0.117
macromolecular complex assembly GO:0065003 193 0.114
signal transduction GO:0007165 317 0.113
chromosome organization GO:0051276 104 0.111
cellular nitrogen compound catabolic process GO:0044270 119 0.111
regulation of meiotic cell cycle GO:0051445 136 0.106
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.104
catabolic process GO:0009056 318 0.103
positive regulation of metabolic process GO:0009893 187 0.103
biosynthetic process GO:0009058 323 0.100
phosphate containing compound metabolic process GO:0006796 232 0.100
organ development GO:0048513 1102 0.099
meiotic chromosome segregation GO:0045132 139 0.099
female gamete generation GO:0007292 254 0.099
regulation of developmental process GO:0050793 684 0.099
cell morphogenesis GO:0000902 163 0.099
gene expression GO:0010467 412 0.099
Human
cellular localization GO:0051641 360 0.097
Human
cell projection assembly GO:0030031 35 0.097
cytoskeleton organization GO:0007010 339 0.095
positive regulation of gene expression GO:0010628 112 0.092
regulation of rna metabolic process GO:0051252 173 0.092
locomotion GO:0040011 1634 0.090
nucleic acid templated transcription GO:0097659 169 0.088
cellular protein metabolic process GO:0044267 279 0.087
establishment of localization GO:0051234 1171 0.086
Human
regulation of cellular biosynthetic process GO:0031326 189 0.085
receptor mediated endocytosis GO:0006898 715 0.083
positive regulation of cellular biosynthetic process GO:0031328 109 0.082
regulation of meiosis GO:0040020 94 0.081
nervous system development GO:0007399 253 0.079
nucleobase containing compound biosynthetic process GO:0034654 184 0.078
positive regulation of nucleic acid templated transcription GO:1903508 102 0.078
regulation of mitotic cell cycle GO:0007346 76 0.076
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.075
transport GO:0006810 1093 0.073
Human
negative regulation of cellular process GO:0048523 239 0.071
cellular component movement GO:0006928 388 0.071
maintenance of location GO:0051235 580 0.070
regulation of nuclear division GO:0051783 115 0.067
gamete generation GO:0007276 461 0.066
establishment of protein localization to membrane GO:0090150 3 0.066
genitalia development GO:0048806 741 0.066
regulation of macromolecule biosynthetic process GO:0010556 189 0.066
positive regulation of macromolecule metabolic process GO:0010604 149 0.066
lipid storage GO:0019915 565 0.066
lipid localization GO:0010876 573 0.065
regulation of primary metabolic process GO:0080090 292 0.064
macromolecule catabolic process GO:0009057 202 0.064
regulation of growth GO:0040008 409 0.063
gonad development GO:0008406 840 0.063
regulation of cell cycle process GO:0010564 145 0.063
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.062
behavior GO:0007610 527 0.061
cellular macromolecule catabolic process GO:0044265 73 0.061
protein complex biogenesis GO:0070271 186 0.061
response to external stimulus GO:0009605 289 0.060
regulation of cellular metabolic process GO:0031323 305 0.060
mitotic sister chromatid segregation GO:0000070 38 0.060
specification of axis polarity GO:0065001 13 0.059
negative regulation of multicellular organismal process GO:0051241 236 0.058
endocytosis GO:0006897 819 0.058
macromolecule localization GO:0033036 771 0.058
Human
death GO:0016265 547 0.058
nucleic acid phosphodiester bond hydrolysis GO:0090305 28 0.055
transcription dna templated GO:0006351 168 0.055
regulation of nucleic acid templated transcription GO:1903506 165 0.055
reproductive system development GO:0061458 850 0.054
vulval development GO:0040025 333 0.054
regulation of multicellular organismal process GO:0051239 726 0.054
signaling GO:0023052 401 0.054
protein metabolic process GO:0019538 422 0.053
dna templated transcription elongation GO:0006354 1 0.053
nucleotide metabolic process GO:0009117 108 0.052
regulation of metabolic process GO:0019222 478 0.052
rna biosynthetic process GO:0032774 169 0.051
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.051
nucleoside phosphate catabolic process GO:1901292 77 0.050
positive regulation of growth GO:0045927 369 0.050
oviposition GO:0018991 364 0.050
chromosome organization involved in meiosis GO:0070192 25 0.049
organelle assembly GO:0070925 214 0.048
regulation of response to stimulus GO:0048583 243 0.048
cellular component assembly involved in morphogenesis GO:0010927 183 0.048
cell death GO:0008219 547 0.048
regulation of cell morphogenesis GO:0022604 40 0.047
regulation of biosynthetic process GO:0009889 189 0.047
protein complex assembly GO:0006461 186 0.046
negative regulation of cellular metabolic process GO:0031324 95 0.046
single organism catabolic process GO:0044712 129 0.046
programmed cell death GO:0012501 500 0.046
single organism reproductive process GO:0044702 1196 0.046
regulation of cell communication GO:0010646 176 0.046
multi organism reproductive behavior GO:0044705 387 0.045
purine nucleoside metabolic process GO:0042278 92 0.044
nucleotide catabolic process GO:0009166 77 0.044
negative regulation of metabolic process GO:0009892 240 0.044
reproductive behavior GO:0019098 387 0.044
organophosphate catabolic process GO:0046434 81 0.043
positive regulation of protein metabolic process GO:0051247 45 0.042
cellular component morphogenesis GO:0032989 318 0.041
heterocycle biosynthetic process GO:0018130 187 0.040
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.040
macromolecule modification GO:0043412 218 0.039
cell development GO:0048468 696 0.039
purine nucleoside triphosphate catabolic process GO:0009146 72 0.038
growth GO:0040007 562 0.037
organic cyclic compound biosynthetic process GO:1901362 195 0.037
regulation of vulval development GO:0040028 248 0.037
ribonucleoside catabolic process GO:0042454 77 0.036
positive regulation of rna biosynthetic process GO:1902680 102 0.036
tube development GO:0035295 126 0.035
purine nucleotide metabolic process GO:0006163 95 0.035
multicellular organism growth GO:0035264 385 0.035
anatomical structure formation involved in morphogenesis GO:0048646 250 0.035
regulation of cell shape GO:0008360 6 0.035
negative regulation of vulval development GO:0040027 206 0.034
developmental growth GO:0048589 412 0.034
chromatin organization GO:0006325 32 0.034
cytokinesis GO:0000910 80 0.034
dna templated transcription initiation GO:0006352 3 0.034
regulation of dna replication GO:0006275 5 0.034
nucleoside catabolic process GO:0009164 78 0.034
vesicle mediated transport GO:0016192 852 0.034
cleavage involved in rrna processing GO:0000469 2 0.033
establishment of localization in cell GO:0051649 318 0.033
Human
cellular macromolecule localization GO:0070727 75 0.033
ribonucleoside triphosphate catabolic process GO:0009203 72 0.033
hermaphrodite genitalia development GO:0040035 734 0.032
purine nucleoside triphosphate metabolic process GO:0009144 87 0.032
cellular macromolecule biosynthetic process GO:0034645 247 0.032
neuron differentiation GO:0030182 217 0.032
regulation of post embryonic development GO:0048580 260 0.031
ribonucleotide metabolic process GO:0009259 99 0.031
multicellular organismal aging GO:0010259 812 0.031
cellular protein localization GO:0034613 75 0.031
regulation of multicellular organism growth GO:0040014 373 0.031
system process GO:0003008 136 0.031
macromolecule biosynthetic process GO:0009059 250 0.031
phosphorus metabolic process GO:0006793 232 0.031
skeletal muscle organ development GO:0060538 3 0.030
neuron projection guidance GO:0097485 82 0.030
multicellular organismal reproductive behavior GO:0033057 384 0.030
intracellular signal transduction GO:0035556 96 0.029
glycosyl compound catabolic process GO:1901658 79 0.029
transcription initiation from rna polymerase ii promoter GO:0006367 2 0.029
sister chromatid segregation GO:0000819 46 0.029
regulation of nematode larval development GO:0061062 260 0.028
single organism signaling GO:0044700 401 0.028
regulation of cellular protein metabolic process GO:0032268 75 0.028
transcription elongation from rna polymerase ii promoter GO:0006368 1 0.027
response to chemical GO:0042221 356 0.027
regulation of behavior GO:0050795 97 0.027
purine containing compound catabolic process GO:0072523 75 0.027
multi multicellular organism process GO:0044706 390 0.027
regulation of protein metabolic process GO:0051246 81 0.027
regulation of multicellular organismal development GO:2000026 317 0.027
positive regulation of developmental growth GO:0048639 354 0.027
positive regulation of catabolic process GO:0009896 38 0.027
single organism transport GO:0044765 447 0.026
Human
cellular biosynthetic process GO:0044249 315 0.026
cellular protein modification process GO:0006464 207 0.026
covalent chromatin modification GO:0016569 30 0.026
positive regulation of neurogenesis GO:0050769 4 0.026
neurogenesis GO:0022008 236 0.026
localization of cell GO:0051674 313 0.025
positive regulation of developmental process GO:0051094 408 0.025
positive regulation of multicellular organismal process GO:0051240 417 0.025
intracellular transport GO:0046907 77 0.025
Human
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.025
ribonucleoside triphosphate metabolic process GO:0009199 87 0.025
protein modification process GO:0036211 207 0.025
multi organism behavior GO:0051705 389 0.024
cuticle development GO:0042335 100 0.024
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.024
response to wounding GO:0009611 4 0.024
amine metabolic process GO:0009308 15 0.024
centrosomal and pronuclear rotation GO:0035047 6 0.024
negative regulation of macromolecule metabolic process GO:0010605 229 0.024
negative regulation of developmental process GO:0051093 227 0.024
regulation of chromosome organization GO:0033044 20 0.024
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.023
ribonucleotide catabolic process GO:0009261 75 0.023
cell migration GO:0016477 306 0.023
regulation of signaling GO:0023051 172 0.023
muscle structure development GO:0061061 191 0.023
protein phosphorylation GO:0006468 85 0.022
cellular nitrogen compound biosynthetic process GO:0044271 192 0.022
anterior posterior axis specification GO:0009948 17 0.022
nucleoside phosphate metabolic process GO:0006753 108 0.022
positive regulation of multicellular organism growth GO:0040018 352 0.022
immune response GO:0006955 192 0.022
negative regulation of biosynthetic process GO:0009890 65 0.022
determination of adult lifespan GO:0008340 812 0.021
regulation of developmental growth GO:0048638 389 0.021
regulation of anatomical structure morphogenesis GO:0022603 51 0.021
development of primary sexual characteristics GO:0045137 840 0.021
small molecule metabolic process GO:0044281 186 0.021
purine nucleotide catabolic process GO:0006195 75 0.021
purine ribonucleoside monophosphate metabolic process GO:0009167 43 0.021
modification dependent macromolecule catabolic process GO:0043632 32 0.020
positive regulation of cellular component organization GO:0051130 34 0.020
carbohydrate derivative catabolic process GO:1901136 82 0.020
actin filament based process GO:0030029 191 0.020
rna localization GO:0006403 3 0.020
Human
regulation of cell proliferation GO:0042127 105 0.020
negative regulation of nematode larval development GO:0061064 208 0.019
developmental process involved in reproduction GO:0003006 1165 0.019
negative regulation of post embryonic development GO:0048581 208 0.019
tissue development GO:0009888 112 0.019
cell type specific apoptotic process GO:0097285 4 0.018
cellular amine metabolic process GO:0044106 15 0.018
regulation of intracellular signal transduction GO:1902531 77 0.018
cell projection morphogenesis GO:0048858 148 0.018
negative regulation of cellular biosynthetic process GO:0031327 65 0.018
regulation of cell motility GO:2000145 57 0.018
taxis GO:0042330 128 0.018
rna polyadenylation GO:0043631 3 0.018
striated muscle cell differentiation GO:0051146 158 0.018
chromatin modification GO:0016568 32 0.018
ribose phosphate metabolic process GO:0019693 99 0.018
nucleoside triphosphate catabolic process GO:0009143 72 0.017
regulation of cellular amine metabolic process GO:0033238 0 0.017
organic substance biosynthetic process GO:1901576 323 0.017
chemotaxis GO:0006935 120 0.017
cellular response to stress GO:0033554 162 0.017
ribonucleoside monophosphate metabolic process GO:0009161 45 0.017
tissue morphogenesis GO:0048729 65 0.017
regulation of signal transduction GO:0009966 135 0.017
aging GO:0007568 812 0.017
nucleoside metabolic process GO:0009116 99 0.017
cellular response to dna damage stimulus GO:0006974 41 0.017
filopodium assembly GO:0046847 2 0.017
generation of neurons GO:0048699 235 0.016
organ morphogenesis GO:0009887 67 0.016
positive regulation of nematode larval development GO:0061063 54 0.016
protein dna complex subunit organization GO:0071824 7 0.016
regulation of gene expression epigenetic GO:0040029 163 0.016
chromatin assembly or disassembly GO:0006333 1 0.016
regulation of cellular ketone metabolic process GO:0010565 3 0.016
negative regulation of gene expression GO:0010629 217 0.016
glycosyl compound metabolic process GO:1901657 100 0.016
regulation of multi organism process GO:0043900 69 0.016
purine ribonucleotide metabolic process GO:0009150 95 0.016
regulation of filopodium assembly GO:0051489 2 0.016
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.015
muscle cell differentiation GO:0042692 171 0.015
ubiquitin dependent protein catabolic process GO:0006511 32 0.015
rna processing GO:0006396 34 0.015
cell projection organization GO:0030030 231 0.015
nucleoside monophosphate metabolic process GO:0009123 46 0.015
phagocytosis GO:0006909 115 0.015
positive regulation of epithelial cell proliferation GO:0050679 1 0.014
positive regulation of chromosome organization GO:2001252 2 0.014
epithelial tube morphogenesis GO:0060562 1 0.014
organonitrogen compound catabolic process GO:1901565 90 0.014
regulation of cell differentiation GO:0045595 81 0.014
carbohydrate derivative metabolic process GO:1901135 141 0.014
spindle organization GO:0007051 92 0.014
carboxylic acid metabolic process GO:0019752 34 0.014
cell cycle phase transition GO:0044770 19 0.014
purine nucleoside monophosphate catabolic process GO:0009128 28 0.013
head development GO:0060322 1 0.013
organic substance transport GO:0071702 113 0.013
Human
regulation of localization GO:0032879 194 0.013
inductive cell migration GO:0040039 145 0.013
negative regulation of rna biosynthetic process GO:1902679 53 0.013
negative regulation of rna metabolic process GO:0051253 53 0.013
peptidyl amino acid modification GO:0018193 58 0.013
purine ribonucleotide catabolic process GO:0009154 75 0.013
purine nucleoside catabolic process GO:0006152 75 0.013
actin cytoskeleton organization GO:0030036 184 0.013
regulation of cell cycle phase transition GO:1901987 13 0.013
protein localization GO:0008104 205 0.013
apoptotic cell clearance GO:0043277 111 0.013
muscle cell development GO:0055001 158 0.013
protein targeting to membrane GO:0006612 1 0.013
cellular protein complex assembly GO:0043623 178 0.012
regulation of chromosome segregation GO:0051983 20 0.012
atp metabolic process GO:0046034 42 0.012
negative regulation of mitotic cell cycle GO:0045930 42 0.012
sensory organ morphogenesis GO:0090596 2 0.012
myosin filament organization GO:0031033 138 0.012
regulation of cell projection assembly GO:0060491 3 0.012
cellular response to nitrogen compound GO:1901699 24 0.012
negative regulation of signaling GO:0023057 61 0.012
regulation of phosphorus metabolic process GO:0051174 81 0.011
digestive system development GO:0055123 122 0.011
positive regulation of molecular function GO:0044093 61 0.011
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 1 0.011
regulation of cell development GO:0060284 49 0.011
atp catabolic process GO:0006200 27 0.011
striated muscle cell development GO:0055002 157 0.011
ribonucleoside metabolic process GO:0009119 98 0.011
myofibril assembly GO:0030239 154 0.011
plasma membrane organization GO:0007009 9 0.011
actin filament organization GO:0007015 21 0.011
cellular amino acid metabolic process GO:0006520 15 0.011
chromatin assembly GO:0031497 1 0.011
regulation of ras protein signal transduction GO:0046578 41 0.011
regulation of cellular amino acid metabolic process GO:0006521 0 0.011
regulation of cell migration GO:0030334 55 0.010
nucleoside triphosphate metabolic process GO:0009141 87 0.010
epithelial cell proliferation GO:0050673 1 0.010

thoc-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.020
nervous system disease DOID:863 0 0.013