Caenorhabditis elegans

28 known processes

nhr-8 (CELE_F33D4.1)

Protein NHR-8

nhr-8 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of rna metabolic process GO:0051252 173 0.330
Zebrafish Mouse Rat Worm Fly
embryo development ending in birth or egg hatching GO:0009792 2992 0.325
regulation of nitrogen compound metabolic process GO:0051171 222 0.321
Zebrafish Mouse Rat Worm Fly
signal transduction GO:0007165 317 0.274
Zebrafish Mouse Rat Worm Fly
nucleobase containing compound biosynthetic process GO:0034654 184 0.209
Zebrafish Mouse Rat Worm Fly
signaling GO:0023052 401 0.200
Zebrafish Mouse Rat Worm Fly
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.192
Mouse Rat Worm Fly
regulation of cellular metabolic process GO:0031323 305 0.190
Zebrafish Mouse Rat Worm Fly
determination of adult lifespan GO:0008340 812 0.189
Fly
cellular biosynthetic process GO:0044249 315 0.184
Zebrafish Mouse Rat Worm Fly
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.181
Mouse Rat Worm Fly
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.174
Mouse Rat Worm Fly
cellular nitrogen compound biosynthetic process GO:0044271 192 0.171
Zebrafish Mouse Rat Worm Fly
organ development GO:0048513 1102 0.170
Fly
nucleobase containing compound metabolic process GO:0006139 406 0.164
Zebrafish Mouse Rat Worm Fly
regulation of cellular biosynthetic process GO:0031326 189 0.161
Zebrafish Mouse Rat Worm Fly
single organism signaling GO:0044700 401 0.157
Zebrafish Mouse Rat Worm Fly
post embryonic development GO:0009791 2152 0.155
aromatic compound biosynthetic process GO:0019438 192 0.155
Zebrafish Mouse Rat Worm Fly
regulation of nucleic acid templated transcription GO:1903506 165 0.153
Zebrafish Mouse Rat Worm Fly
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.144
Zebrafish Mouse Rat Worm Fly
heterocycle biosynthetic process GO:0018130 187 0.141
Zebrafish Mouse Rat Worm Fly
regulation of rna biosynthetic process GO:2001141 165 0.139
Zebrafish Mouse Rat Worm Fly
rna biosynthetic process GO:0032774 169 0.138
Zebrafish Mouse Rat Worm Fly
cellular macromolecule biosynthetic process GO:0034645 247 0.134
Zebrafish Mouse Rat Worm Fly
growth GO:0040007 562 0.129
Fly
sex differentiation GO:0007548 909 0.125
regulation of gene expression GO:0010468 366 0.123
Zebrafish Mouse Rat Worm Fly
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.119
Zebrafish Mouse Rat Worm Fly
locomotion GO:0040011 1634 0.114
Fly
positive regulation of nucleic acid templated transcription GO:1903508 102 0.113
Mouse Rat Worm Fly
transcription dna templated GO:0006351 168 0.112
Zebrafish Mouse Rat Worm Fly
cellular response to organic substance GO:0071310 119 0.110
Mouse Rat Fly
multicellular organismal aging GO:0010259 812 0.108
Fly
regulation of primary metabolic process GO:0080090 292 0.108
Zebrafish Mouse Rat Worm Fly
negative regulation of biological process GO:0048519 567 0.106
Mouse Rat Fly
organelle organization GO:0006996 783 0.104
establishment of localization GO:0051234 1171 0.104
Mouse Fly
positive regulation of cellular process GO:0048522 332 0.100
Mouse Rat Worm Fly
regulation of transcription dna templated GO:0006355 164 0.100
Zebrafish Mouse Rat Worm Fly
regulation of cell differentiation GO:0045595 81 0.100
Fly
negative regulation of cellular process GO:0048523 239 0.098
Mouse Fly
cell migration GO:0016477 306 0.097
Fly
embryo development GO:0009790 3052 0.096
nucleic acid metabolic process GO:0090304 299 0.095
Zebrafish Mouse Rat Worm Fly
organic cyclic compound biosynthetic process GO:1901362 195 0.093
Zebrafish Mouse Rat Worm Fly
organonitrogen compound metabolic process GO:1901564 151 0.092
gonad development GO:0008406 840 0.092
macromolecule localization GO:0033036 771 0.091
biosynthetic process GO:0009058 323 0.089
Zebrafish Mouse Rat Worm Fly
regulation of developmental process GO:0050793 684 0.088
Worm Fly
multicellular organismal reproductive behavior GO:0033057 384 0.088
Worm
regulation of multicellular organismal development GO:2000026 317 0.087
Fly
regulation of signaling GO:0023051 172 0.087
development of primary sexual characteristics GO:0045137 840 0.085
organic substance biosynthetic process GO:1901576 323 0.085
Zebrafish Mouse Rat Worm Fly
regulation of biosynthetic process GO:0009889 189 0.082
Zebrafish Mouse Rat Worm Fly
endocytosis GO:0006897 819 0.082
Fly
positive regulation of rna metabolic process GO:0051254 103 0.082
Mouse Rat Worm Fly
cell cycle GO:0007049 526 0.081
nervous system development GO:0007399 253 0.081
Fly
regulation of biological quality GO:0065008 741 0.079
cell projection organization GO:0030030 231 0.078
Fly
regulation of macromolecule biosynthetic process GO:0010556 189 0.077
Zebrafish Mouse Rat Worm Fly
positive regulation of cellular biosynthetic process GO:0031328 109 0.076
Mouse Rat Worm Fly
cellular catabolic process GO:0044248 199 0.075
Fly
behavior GO:0007610 527 0.073
Worm Fly
positive regulation of gene expression GO:0010628 112 0.073
Mouse Rat Worm Fly
response to organic substance GO:0010033 131 0.072
Mouse Rat Fly
reproductive system development GO:0061458 850 0.071
rna metabolic process GO:0016070 228 0.071
Zebrafish Mouse Rat Worm Fly
vesicle mediated transport GO:0016192 852 0.070
Fly
cell development GO:0048468 696 0.069
Fly
reproductive structure development GO:0048608 850 0.069
multi organism reproductive behavior GO:0044705 387 0.069
Worm
aging GO:0007568 812 0.069
Fly
response to chemical GO:0042221 356 0.069
Mouse Rat Fly
developmental process involved in reproduction GO:0003006 1165 0.069
Fly
lipid localization GO:0010876 573 0.068
multi organism reproductive process GO:0044703 867 0.065
Worm Fly
positive regulation of rna biosynthetic process GO:1902680 102 0.065
Mouse Rat Worm Fly
lipid storage GO:0019915 565 0.065
regulation of multicellular organismal process GO:0051239 726 0.065
Mouse Fly
receptor mediated endocytosis GO:0006898 715 0.064
maintenance of location GO:0051235 580 0.064
nucleic acid templated transcription GO:0097659 169 0.064
Zebrafish Mouse Rat Worm Fly
small molecule metabolic process GO:0044281 186 0.063
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.062
Mouse Rat Worm Fly
regulation of macromolecule metabolic process GO:0060255 421 0.062
Zebrafish Mouse Rat Worm Fly
regulation of response to wounding GO:1903034 1 0.061
Mouse
cellular component movement GO:0006928 388 0.060
Fly
generation of neurons GO:0048699 235 0.060
Fly
transport GO:0006810 1093 0.060
Mouse Fly
defense response GO:0006952 296 0.059
Mouse
gamete generation GO:0007276 461 0.059
Fly
single organism organelle organization GO:1902589 501 0.059
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.057
Zebrafish Mouse Rat Worm Fly
positive regulation of developmental process GO:0051094 408 0.056
macromolecule biosynthetic process GO:0009059 250 0.055
Zebrafish Mouse Rat Worm Fly
regulation of response to stimulus GO:0048583 243 0.054
Mouse Worm Fly
oviposition GO:0018991 364 0.054
protein metabolic process GO:0019538 422 0.054
Mouse
cellular response to stress GO:0033554 162 0.053
transcription from rna polymerase ii promoter GO:0006366 149 0.053
Zebrafish Mouse Rat Worm Fly
phosphorus metabolic process GO:0006793 232 0.053
single organism reproductive process GO:0044702 1196 0.053
Fly
positive regulation of signaling GO:0023056 66 0.052
organophosphate metabolic process GO:0019637 125 0.051
multicellular organismal reproductive process GO:0048609 815 0.051
Worm Fly
protein modification process GO:0036211 207 0.050
tube development GO:0035295 126 0.049
Fly
negative regulation of metabolic process GO:0009892 240 0.049
Mouse Rat
regulation of cell communication GO:0010646 176 0.048
regulation of metabolic process GO:0019222 478 0.047
Zebrafish Mouse Rat Worm Fly
cellular response to chemical stimulus GO:0070887 129 0.047
Mouse Rat Fly
reproductive behavior GO:0019098 387 0.047
Worm
cellular component biogenesis GO:0044085 297 0.046
Mouse
negative regulation of macromolecule metabolic process GO:0010605 229 0.046
Mouse Rat
neuron differentiation GO:0030182 217 0.044
Fly
cell division GO:0051301 262 0.044
multicellular organism reproduction GO:0032504 819 0.043
Worm Fly
multi organism behavior GO:0051705 389 0.042
Worm
positive regulation of biosynthetic process GO:0009891 109 0.042
Mouse Rat Worm Fly
multi multicellular organism process GO:0044706 390 0.042
Worm
regulation of developmental growth GO:0048638 389 0.042
developmental growth GO:0048589 412 0.041
single organism carbohydrate metabolic process GO:0044723 29 0.041
small molecule biosynthetic process GO:0044283 38 0.041
regulation of synaptic transmission GO:0050804 34 0.041
cellular protein metabolic process GO:0044267 279 0.040
Mouse
response to wounding GO:0009611 4 0.039
Mouse
regulation of cellular component organization GO:0051128 248 0.039
Mouse
apoptotic process GO:0006915 478 0.039
Fly
positive regulation of multicellular organism growth GO:0040018 352 0.038
negative regulation of gene expression GO:0010629 217 0.038
Mouse Rat
cellular component assembly GO:0022607 293 0.038
Mouse
regulation of multicellular organism growth GO:0040014 373 0.037
positive regulation of multicellular organismal process GO:0051240 417 0.037
Mouse Fly
cell cycle process GO:0022402 482 0.037
carbohydrate metabolic process GO:0005975 34 0.036
response to acid chemical GO:0001101 4 0.036
organic substance catabolic process GO:1901575 294 0.036
multicellular organism growth GO:0035264 385 0.035
synaptic transmission GO:0007268 106 0.035
regulation of growth GO:0040008 409 0.035
Fly
cell death GO:0008219 547 0.034
Fly
localization of cell GO:0051674 313 0.034
Fly
cellular component morphogenesis GO:0032989 318 0.033
Fly
neuron projection development GO:0031175 187 0.033
Fly
gene expression GO:0010467 412 0.033
Zebrafish Mouse Rat Worm Fly
cell motility GO:0048870 313 0.032
Fly
tube morphogenesis GO:0035239 79 0.032
Fly
er nucleus signaling pathway GO:0006984 66 0.032
embryonic morphogenesis GO:0048598 152 0.031
Fly
neuron development GO:0048666 199 0.031
Fly
catabolic process GO:0009056 318 0.031
Fly
response to topologically incorrect protein GO:0035966 82 0.031
macromolecule modification GO:0043412 218 0.031
membrane fusion GO:0061025 16 0.031
single organism transport GO:0044765 447 0.031
Mouse Fly
regulation of cellular ketone metabolic process GO:0010565 3 0.030
cellular response to topologically incorrect protein GO:0035967 76 0.030
meiotic nuclear division GO:0007126 300 0.029
phagocytosis engulfment GO:0006911 98 0.029
Fly
protein complex subunit organization GO:0071822 280 0.029
positive regulation of growth GO:0045927 369 0.029
neurogenesis GO:0022008 236 0.029
Fly
organelle fission GO:0048285 363 0.029
macromolecular complex subunit organization GO:0043933 320 0.028
Mouse
negative regulation of developmental process GO:0051093 227 0.028
Fly
positive regulation of macromolecule metabolic process GO:0010604 149 0.027
Mouse Rat Worm Fly
regulation of lipid biosynthetic process GO:0046890 1 0.027
gene silencing by rna GO:0031047 143 0.027
cytoskeleton organization GO:0007010 339 0.027
adult behavior GO:0030534 3 0.026
death GO:0016265 547 0.026
Fly
single organism catabolic process GO:0044712 129 0.026
meiotic cell cycle GO:0051321 335 0.026
positive regulation of transcription from rna polymerase ii promoter involved in defense response to gram negative bacterium GO:1902097 4 0.025
regulation of signal transduction GO:0009966 135 0.025
positive regulation of cellular metabolic process GO:0031325 178 0.025
Mouse Rat Worm Fly
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 2 0.025
posttranscriptional regulation of gene expression GO:0010608 166 0.025
head development GO:0060322 1 0.024
Fly
hermaphrodite genitalia development GO:0040035 734 0.024
gene silencing GO:0016458 143 0.023
cellular protein modification process GO:0006464 207 0.023
epithelial tube morphogenesis GO:0060562 1 0.023
Fly
phosphorylation GO:0016310 116 0.023
phosphate containing compound metabolic process GO:0006796 232 0.023
positive regulation of transcription dna templated GO:0045893 102 0.023
Mouse Rat Worm Fly
protein phosphorylation GO:0006468 85 0.023
response to endoplasmic reticulum stress GO:0034976 71 0.023
single organism localization GO:1902578 518 0.022
Mouse Fly
membrane organization GO:0061024 135 0.022
Fly
carbohydrate derivative metabolic process GO:1901135 141 0.022
protein complex assembly GO:0006461 186 0.022
rna interference GO:0016246 137 0.022
cell morphogenesis GO:0000902 163 0.022
Fly
digestive tract development GO:0048565 122 0.022
Fly
macromolecule catabolic process GO:0009057 202 0.021
organic substance transport GO:0071702 113 0.021
Mouse
carboxylic acid metabolic process GO:0019752 34 0.021
regulation of lipid metabolic process GO:0019216 4 0.021
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.021
calcium mediated signaling GO:0019722 3 0.020
posttranscriptional gene silencing GO:0016441 143 0.020
muscle cell development GO:0055001 158 0.020
positive regulation of cell communication GO:0010647 69 0.020
organic acid metabolic process GO:0006082 47 0.020
system process GO:0003008 136 0.020
Mouse Fly
apoptotic cell clearance GO:0043277 111 0.019
posttranscriptional gene silencing by rna GO:0035194 143 0.019
cellular ketone metabolic process GO:0042180 14 0.019
positive regulation of response to stimulus GO:0048584 55 0.019
Fly
single organism biosynthetic process GO:0044711 91 0.019
body morphogenesis GO:0010171 620 0.019
regulation of gene expression epigenetic GO:0040029 163 0.019
cytokinesis GO:0000910 80 0.019
single organism behavior GO:0044708 83 0.019
Fly
myosin filament organization GO:0031033 138 0.019
organonitrogen compound biosynthetic process GO:1901566 44 0.018
positive regulation of developmental growth GO:0048639 354 0.018
molting cycle GO:0042303 281 0.018
Fly
cellular component assembly involved in morphogenesis GO:0010927 183 0.018
cell surface receptor signaling pathway GO:0007166 149 0.018
Rat
development of primary male sexual characteristics GO:0046546 4 0.018
regulation of cell proliferation GO:0042127 105 0.017
Fly
protein complex biogenesis GO:0070271 186 0.017
enzyme linked receptor protein signaling pathway GO:0007167 50 0.017
Rat
microvillus assembly GO:0030033 1 0.017
anatomical structure formation involved in morphogenesis GO:0048646 250 0.017
Fly
myosin filament assembly GO:0031034 138 0.017
cellular amine metabolic process GO:0044106 15 0.017
regulation of cellular amine metabolic process GO:0033238 0 0.017
cellular response to unfolded protein GO:0034620 71 0.017
regulation of neuromuscular synaptic transmission GO:1900073 1 0.017
oogenesis GO:0048477 229 0.017
Fly
aromatic compound catabolic process GO:0019439 116 0.016
regulation of multi organism process GO:0043900 69 0.016
Fly
cell type specific apoptotic process GO:0097285 4 0.016
phagocytosis GO:0006909 115 0.016
Fly
cell proliferation GO:0008283 116 0.015
Fly
neurological system process GO:0050877 53 0.015
Fly
response to extracellular stimulus GO:0009991 38 0.015
regulation of molecular function GO:0065009 89 0.015
negative regulation of post embryonic development GO:0048581 208 0.015
oxoacid metabolic process GO:0043436 47 0.015
positive regulation of neuron differentiation GO:0045666 4 0.015
cell projection morphogenesis GO:0048858 148 0.015
Fly
nucleobase containing small molecule metabolic process GO:0055086 115 0.015
regulation of nervous system development GO:0051960 41 0.015
Fly
regulation of cellular amino acid metabolic process GO:0006521 0 0.015
cell part morphogenesis GO:0032990 152 0.015
Fly
axon development GO:0061564 163 0.015
Fly
regulation of cellular localization GO:0060341 42 0.015
Mouse
digestive system development GO:0055123 122 0.014
Fly
negative regulation of cell communication GO:0010648 61 0.014
female gamete generation GO:0007292 254 0.014
Fly
nucleotide metabolic process GO:0009117 108 0.014
innate immune response GO:0045087 190 0.014
negative regulation of response to stimulus GO:0048585 73 0.014
Mouse
establishment of localization in cell GO:0051649 318 0.014
Mouse
response to external biotic stimulus GO:0043207 101 0.014
Mouse
organelle assembly GO:0070925 214 0.014
cellular amino acid metabolic process GO:0006520 15 0.014
dauer larval development GO:0040024 92 0.014
Worm
negative regulation of response to external stimulus GO:0032102 3 0.013
Mouse
purine ribonucleoside metabolic process GO:0046128 92 0.013
defense response to other organism GO:0098542 100 0.013
nucleoside phosphate metabolic process GO:0006753 108 0.013
membrane invagination GO:0010324 98 0.013
Fly
purine containing compound metabolic process GO:0072521 95 0.013
peptidyl tyrosine phosphorylation GO:0018108 2 0.013
germ cell development GO:0007281 351 0.013
Fly
response to unfolded protein GO:0006986 71 0.013
programmed cell death GO:0012501 500 0.013
Fly
learning or memory GO:0007611 27 0.013
Fly
response to osmotic stress GO:0006970 29 0.013
secretion GO:0046903 147 0.013
Mouse
positive regulation of transcription from rna polymerase ii promoter in response to osmotic stress GO:0061393 1 0.013
regulation of protein metabolic process GO:0051246 81 0.013
Mouse
response to external stimulus GO:0009605 289 0.013
Mouse
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.013
engulfment of apoptotic cell GO:0043652 94 0.012
amine metabolic process GO:0009308 15 0.012
response to insulin GO:0032868 14 0.012
Rat
regulation of cell cell adhesion GO:0022407 1 0.012
macromolecular complex assembly GO:0065003 193 0.012
Mouse
negative regulation of cellular metabolic process GO:0031324 95 0.012
Mouse
single organism intracellular transport GO:1902582 70 0.012
negative regulation of multicellular organismal process GO:0051241 236 0.012
Mouse Fly
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 2 0.012
defense response to gram negative bacterium GO:0050829 64 0.012
vulval development GO:0040025 333 0.012
regulation of cellular protein metabolic process GO:0032268 75 0.012
Mouse
ribonucleoside metabolic process GO:0009119 98 0.012
positive regulation of neurogenesis GO:0050769 4 0.012
regulation of cell cycle GO:0051726 194 0.012
cellular protein complex assembly GO:0043623 178 0.011
organism emergence from protective structure GO:0071684 48 0.011
Fly
genitalia development GO:0048806 741 0.011
protein localization GO:0008104 205 0.011
Mouse
positive regulation of epithelial cell proliferation GO:0050679 1 0.011
guanosine containing compound catabolic process GO:1901069 48 0.011
collagen and cuticulin based cuticle development GO:0040002 99 0.011
lipid oxidation GO:0034440 1 0.011
inductive cell migration GO:0040039 145 0.011
adult locomotory behavior GO:0008344 1 0.011
sexual reproduction GO:0019953 546 0.011
Worm Fly
tissue development GO:0009888 112 0.011
Fly
lipid biosynthetic process GO:0008610 28 0.010
purine nucleotide metabolic process GO:0006163 95 0.010
ion transport GO:0006811 113 0.010
nucleoside triphosphate metabolic process GO:0009141 87 0.010
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.010
Mouse
regulation of cell cycle process GO:0010564 145 0.010
peptidyl amino acid modification GO:0018193 58 0.010
response to oxidative stress GO:0006979 42 0.010
regulation of transport GO:0051049 91 0.010
Mouse
response to oxygen containing compound GO:1901700 44 0.010
Mouse Rat Fly
male anatomical structure morphogenesis GO:0090598 78 0.010
regulation of nucleocytoplasmic transport GO:0046822 3 0.010

nhr-8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.020
nervous system disease DOID:863 0 0.011