Caenorhabditis elegans

49 known processes

let-502 (CELE_C10H11.9)

Protein LET-502

let-502 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
gamete generation GO:0007276 461 0.966
Fly
embryo development ending in birth or egg hatching GO:0009792 2992 0.906
aromatic compound biosynthetic process GO:0019438 192 0.900
sexual reproduction GO:0019953 546 0.893
Fly
multicellular organism reproduction GO:0032504 819 0.881
Fly
development of primary sexual characteristics GO:0045137 840 0.861
genitalia development GO:0048806 741 0.829
regulation of cellular metabolic process GO:0031323 305 0.824
Fly
negative regulation of cellular metabolic process GO:0031324 95 0.771
regulation of transcription dna templated GO:0006355 164 0.760
sex differentiation GO:0007548 909 0.744
heterocycle biosynthetic process GO:0018130 187 0.736
multicellular organismal reproductive process GO:0048609 815 0.736
Fly
hermaphrodite genitalia development GO:0040035 734 0.720
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.692
Fly
post embryonic development GO:0009791 2152 0.688
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.683
developmental process involved in reproduction GO:0003006 1165 0.679
Fly
transport GO:0006810 1093 0.656
Fly
organ development GO:0048513 1102 0.622
Human Zebrafish Fly
cellular macromolecule biosynthetic process GO:0034645 247 0.621
nucleic acid metabolic process GO:0090304 299 0.620
locomotion GO:0040011 1634 0.616
germ cell development GO:0007281 351 0.604
Fly
single organism reproductive process GO:0044702 1196 0.584
Fly
negative regulation of macromolecule metabolic process GO:0010605 229 0.578
regulation of gene expression GO:0010468 366 0.577
organic cyclic compound biosynthetic process GO:1901362 195 0.571
establishment of localization GO:0051234 1171 0.554
Fly
reproductive system development GO:0061458 850 0.548
multi organism reproductive process GO:0044703 867 0.547
Fly
gonad development GO:0008406 840 0.533
rna biosynthetic process GO:0032774 169 0.514
reproductive structure development GO:0048608 850 0.513
cellular biosynthetic process GO:0044249 315 0.510
regulation of biosynthetic process GO:0009889 189 0.502
regulation of nucleic acid templated transcription GO:1903506 165 0.484
nervous system development GO:0007399 253 0.475
Mouse Fly
negative regulation of transcription dna templated GO:0045892 53 0.426
negative regulation of cellular process GO:0048523 239 0.424
Mouse
transcription dna templated GO:0006351 168 0.420
negative regulation of nucleic acid templated transcription GO:1903507 53 0.415
cell development GO:0048468 696 0.411
Mouse Fly
gene expression GO:0010467 412 0.400
cell morphogenesis GO:0000902 163 0.394
regulation of rna biosynthetic process GO:2001141 165 0.389
meiotic cell cycle GO:0051321 335 0.387
macromolecular complex subunit organization GO:0043933 320 0.380
Fly
nucleic acid templated transcription GO:0097659 169 0.377
neuron projection guidance GO:0097485 82 0.377
meiotic nuclear division GO:0007126 300 0.374
organelle fission GO:0048285 363 0.370
Fly
body morphogenesis GO:0010171 620 0.363
cellular response to stress GO:0033554 162 0.353
macromolecule biosynthetic process GO:0009059 250 0.336
biosynthetic process GO:0009058 323 0.323
organic substance biosynthetic process GO:1901576 323 0.315
negative regulation of biological process GO:0048519 567 0.312
Human Mouse Fly
endocytosis GO:0006897 819 0.311
regulation of macromolecule biosynthetic process GO:0010556 189 0.311
nucleobase containing compound metabolic process GO:0006139 406 0.307
protein metabolic process GO:0019538 422 0.303
Human Zebrafish Fly
cellular protein modification process GO:0006464 207 0.302
Human Fly
embryo development GO:0009790 3052 0.300
regulation of rna metabolic process GO:0051252 173 0.299
rna metabolic process GO:0016070 228 0.292
regulation of metabolic process GO:0019222 478 0.267
Fly
single organism signaling GO:0044700 401 0.265
Zebrafish Mouse Fly
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.265
nucleobase containing compound biosynthetic process GO:0034654 184 0.264
receptor mediated endocytosis GO:0006898 715 0.262
regulation of meiosis GO:0040020 94 0.258
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.254
cellular component morphogenesis GO:0032989 318 0.254
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.241
positive regulation of cellular metabolic process GO:0031325 178 0.240
death GO:0016265 547 0.239
cellular component biogenesis GO:0044085 297 0.238
Mouse Fly
regulation of cellular component organization GO:0051128 248 0.233
negative regulation of rna metabolic process GO:0051253 53 0.224
negative regulation of biosynthetic process GO:0009890 65 0.220
axon guidance GO:0007411 82 0.220
cell death GO:0008219 547 0.213
regulation of developmental process GO:0050793 684 0.210
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.207
response to external stimulus GO:0009605 289 0.207
negative regulation of gene expression GO:0010629 217 0.204
neurogenesis GO:0022008 236 0.199
Mouse Fly
regulation of primary metabolic process GO:0080090 292 0.196
Fly
single organism organelle organization GO:1902589 501 0.195
Human Zebrafish Mouse Fly
negative regulation of cellular biosynthetic process GO:0031327 65 0.190
macromolecule modification GO:0043412 218 0.190
Human Fly
head development GO:0060322 1 0.188
regulation of cellular biosynthetic process GO:0031326 189 0.188
spindle organization GO:0007051 92 0.188
Fly
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.184
signal transduction GO:0007165 317 0.184
Zebrafish Mouse Fly
programmed cell death GO:0012501 500 0.182
regulation of nitrogen compound metabolic process GO:0051171 222 0.180
regulation of cell communication GO:0010646 176 0.178
Fly
negative regulation of metabolic process GO:0009892 240 0.176
positive regulation of cellular process GO:0048522 332 0.172
Mouse Fly
muscle cell differentiation GO:0042692 171 0.162
regulation of cellular protein metabolic process GO:0032268 75 0.159
Fly
negative regulation of rna biosynthetic process GO:1902679 53 0.156
protein complex subunit organization GO:0071822 280 0.155
Fly
multi organism behavior GO:0051705 389 0.153
cellular localization GO:0051641 360 0.152
Fly
axonogenesis GO:0007409 102 0.151
Fly
regulation of vulval development GO:0040028 248 0.149
regulation of multicellular organismal development GO:2000026 317 0.145
Human Zebrafish Fly
cellular response to dna damage stimulus GO:0006974 41 0.145
multicellular organismal reproductive behavior GO:0033057 384 0.144
tube development GO:0035295 126 0.142
Zebrafish Mouse Fly
apoptotic process GO:0006915 478 0.141
cellular nitrogen compound biosynthetic process GO:0044271 192 0.140
cell morphogenesis involved in differentiation GO:0000904 112 0.140
Mouse Fly
regulation of protein metabolic process GO:0051246 81 0.138
Fly
cellular component movement GO:0006928 388 0.137
vesicle mediated transport GO:0016192 852 0.136
cytoskeleton organization GO:0007010 339 0.136
Human Zebrafish Mouse Fly
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.135
Mouse Fly
regulation of signaling GO:0023051 172 0.134
Fly
regulation of biological quality GO:0065008 741 0.132
organelle organization GO:0006996 783 0.132
Human Zebrafish Mouse Fly
negative regulation of vulval development GO:0040027 206 0.130
cellular protein metabolic process GO:0044267 279 0.127
Human Zebrafish Fly
cellular macromolecular complex assembly GO:0034622 184 0.120
response to chemical GO:0042221 356 0.119
cellular component assembly GO:0022607 293 0.118
Mouse Fly
oviposition GO:0018991 364 0.118
phosphorus metabolic process GO:0006793 232 0.114
Human Fly
regulation of multicellular organismal process GO:0051239 726 0.113
Human Zebrafish Fly
cell projection organization GO:0030030 231 0.113
Mouse Fly
protein modification process GO:0036211 207 0.109
Human Fly
regulation of apoptotic process GO:0042981 36 0.109
Mouse
carbohydrate derivative metabolic process GO:1901135 141 0.107
mitotic cell cycle process GO:1903047 194 0.106
Fly
catabolic process GO:0009056 318 0.104
Zebrafish
rna processing GO:0006396 34 0.102
organelle assembly GO:0070925 214 0.101
cell fate commitment GO:0045165 139 0.100
determination of adult lifespan GO:0008340 812 0.100
negative regulation of nematode larval development GO:0061064 208 0.098
transcription from rna polymerase ii promoter GO:0006366 149 0.095
establishment of localization in cell GO:0051649 318 0.095
Fly
muscle cell development GO:0055001 158 0.094
macromolecular complex assembly GO:0065003 193 0.092
meiotic cell cycle process GO:1903046 170 0.092
macromolecule catabolic process GO:0009057 202 0.091
Zebrafish
purine nucleoside catabolic process GO:0006152 75 0.091
regulation of macromolecule metabolic process GO:0060255 421 0.090
Fly
signaling GO:0023052 401 0.090
Zebrafish Mouse Fly
cell cycle process GO:0022402 482 0.089
Human Mouse Fly
macromolecule localization GO:0033036 771 0.088
Fly
cellular protein complex assembly GO:0043623 178 0.086
protein catabolic process GO:0030163 162 0.086
Zebrafish
purine ribonucleotide catabolic process GO:0009154 75 0.085
single organism transport GO:0044765 447 0.084
Fly
protein complex biogenesis GO:0070271 186 0.084
positive regulation of cellular biosynthetic process GO:0031328 109 0.083
protein complex assembly GO:0006461 186 0.082
negative regulation of developmental process GO:0051093 227 0.080
Human
regulation of nematode larval development GO:0061062 260 0.080
nucleoside triphosphate catabolic process GO:0009143 72 0.077
digestive tract development GO:0048565 122 0.075
Zebrafish Fly
posttranscriptional regulation of gene expression GO:0010608 166 0.074
positive regulation of macromolecule metabolic process GO:0010604 149 0.074
cellular macromolecule localization GO:0070727 75 0.074
Fly
mrna metabolic process GO:0016071 31 0.074
regulation of nervous system development GO:0051960 41 0.073
Fly
chemotaxis GO:0006935 120 0.073
developmental growth GO:0048589 412 0.072
Fly
reproductive behavior GO:0019098 387 0.070
regulation of nuclear division GO:0051783 115 0.070
anatomical structure formation involved in morphogenesis GO:0048646 250 0.070
Human Zebrafish Mouse
multi multicellular organism process GO:0044706 390 0.070
cellular nitrogen compound catabolic process GO:0044270 119 0.070
muscle structure development GO:0061061 191 0.069
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.069
mitotic nuclear division GO:0007067 89 0.069
Fly
multi organism reproductive behavior GO:0044705 387 0.068
heterocycle catabolic process GO:0046700 119 0.068
cellular component assembly involved in morphogenesis GO:0010927 183 0.067
organic substance catabolic process GO:1901575 294 0.065
Zebrafish
purine containing compound metabolic process GO:0072521 95 0.065
lipid storage GO:0019915 565 0.065
cell proliferation GO:0008283 116 0.065
positive regulation of catalytic activity GO:0043085 59 0.065
positive regulation of metabolic process GO:0009893 187 0.064
cell part morphogenesis GO:0032990 152 0.064
Mouse Fly
actomyosin structure organization GO:0031032 154 0.063
Fly
maintenance of location GO:0051235 580 0.063
Fly
regulation of gene expression epigenetic GO:0040029 163 0.061
embryonic morphogenesis GO:0048598 152 0.061
tissue development GO:0009888 112 0.061
Human Zebrafish Mouse Fly
purine nucleoside metabolic process GO:0042278 92 0.061
glycosyl compound metabolic process GO:1901657 100 0.060
nucleobase containing compound catabolic process GO:0034655 114 0.060
single fertilization GO:0007338 61 0.059
response to organic substance GO:0010033 131 0.059
fertilization GO:0009566 63 0.059
meiotic chromosome segregation GO:0045132 139 0.059
organic cyclic compound catabolic process GO:1901361 119 0.059
negative regulation of transcription from rna polymerase ii promoter GO:0000122 45 0.057
single organism catabolic process GO:0044712 129 0.057
striated muscle cell development GO:0055002 157 0.057
lipid localization GO:0010876 573 0.055
regulation of protein catabolic process GO:0042176 13 0.053
cell division GO:0051301 262 0.053
Fly
cell surface receptor signaling pathway GO:0007166 149 0.053
Zebrafish Mouse Fly
chromosome segregation GO:0007059 180 0.051
regulation of cell division GO:0051302 142 0.050
multicellular organismal aging GO:0010259 812 0.050
behavior GO:0007610 527 0.049
membrane organization GO:0061024 135 0.049
negative regulation of multicellular organismal process GO:0051241 236 0.047
Human
protein phosphorylation GO:0006468 85 0.046
Human Fly
regulation of mitotic metaphase anaphase transition GO:0030071 5 0.046
regulation of response to stimulus GO:0048583 243 0.046
Fly
spindle assembly GO:0051225 8 0.046
regulation of response to wounding GO:1903034 1 0.045
Fly
oogenesis GO:0048477 229 0.045
Fly
purine ribonucleoside catabolic process GO:0046130 75 0.044
male gamete generation GO:0048232 41 0.044
organonitrogen compound metabolic process GO:1901564 151 0.044
vulval development GO:0040025 333 0.043
cellular response to chemical stimulus GO:0070887 129 0.043
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.043
small molecule metabolic process GO:0044281 186 0.043
aging GO:0007568 812 0.043
myofibril assembly GO:0030239 154 0.042
spermatogenesis GO:0007283 41 0.042
sister chromatid segregation GO:0000819 46 0.042
regulation of locomotion GO:0040012 161 0.042
regulation of cell projection organization GO:0031344 38 0.041
Fly
positive regulation of developmental process GO:0051094 408 0.041
ribonucleotide catabolic process GO:0009261 75 0.041
positive regulation of nucleic acid templated transcription GO:1903508 102 0.040
regulation of cell cycle process GO:0010564 145 0.040
Mouse
regulation of post embryonic development GO:0048580 260 0.040
cell type specific apoptotic process GO:0097285 4 0.040
Mouse
phosphate containing compound metabolic process GO:0006796 232 0.040
Human Fly
nucleoside triphosphate metabolic process GO:0009141 87 0.040
growth GO:0040007 562 0.039
Fly
response to abiotic stimulus GO:0009628 152 0.039
striated muscle cell differentiation GO:0051146 158 0.038
tissue morphogenesis GO:0048729 65 0.038
Zebrafish Mouse Fly
intracellular signal transduction GO:0035556 96 0.038
Fly
ribonucleotide metabolic process GO:0009259 99 0.038
purine nucleoside triphosphate catabolic process GO:0009146 72 0.037
chromosome organization GO:0051276 104 0.037
cellular protein localization GO:0034613 75 0.037
Fly
nucleotide catabolic process GO:0009166 77 0.037
molting cycle GO:0042303 281 0.037
negative regulation of protein metabolic process GO:0051248 27 0.037
glycosyl compound catabolic process GO:1901658 79 0.037
female gamete generation GO:0007292 254 0.037
Fly
axon development GO:0061564 163 0.036
Fly
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.036
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 5 0.035
single organism localization GO:1902578 518 0.035
Fly
negative regulation of chromosome segregation GO:0051985 4 0.034
dna metabolic process GO:0006259 74 0.034
organ morphogenesis GO:0009887 67 0.033
Zebrafish Fly
metaphase anaphase transition of mitotic cell cycle GO:0007091 10 0.033
protein modification by small protein conjugation or removal GO:0070647 40 0.032
regulation of cytoplasmic transport GO:1903649 3 0.032
positive regulation of rna metabolic process GO:0051254 103 0.032
positive regulation of protein metabolic process GO:0051247 45 0.032
organonitrogen compound catabolic process GO:1901565 90 0.031
cellular response to abiotic stimulus GO:0071214 4 0.031
regulation of cell cycle GO:0051726 194 0.031
Mouse
striated muscle myosin thick filament assembly GO:0071688 138 0.031
purine nucleoside monophosphate metabolic process GO:0009126 43 0.030
wnt signaling pathway GO:0016055 27 0.030
Zebrafish Fly
cellular catabolic process GO:0044248 199 0.030
Zebrafish
negative regulation of gene expression epigenetic GO:0045814 2 0.030
regeneration GO:0031099 4 0.030
purine nucleoside triphosphate metabolic process GO:0009144 87 0.030
cellular macromolecule catabolic process GO:0044265 73 0.030
Zebrafish
cell recognition GO:0008037 85 0.030
positive regulation of growth GO:0045927 369 0.029
taxis GO:0042330 128 0.029
negative regulation of cellular component organization GO:0051129 33 0.028
nucleoside metabolic process GO:0009116 99 0.028
post embryonic organ development GO:0048569 336 0.028
Fly
regulation of meiotic cell cycle GO:0051445 136 0.027
localization of cell GO:0051674 313 0.027
neuron development GO:0048666 199 0.027
Mouse Fly
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.027
organic substance transport GO:0071702 113 0.027
Fly
maintenance of protein location in cell GO:0032507 12 0.026
Fly
phagocytosis GO:0006909 115 0.026
cellular protein catabolic process GO:0044257 37 0.026
Zebrafish
proteolysis GO:0006508 61 0.026
positive regulation of cell communication GO:0010647 69 0.026
pronuclear migration GO:0035046 51 0.026
positive regulation of signal transduction GO:0009967 40 0.026
regulation of growth GO:0040008 409 0.026
Fly
protein localization GO:0008104 205 0.026
Fly
positive regulation of rna biosynthetic process GO:1902680 102 0.026
organophosphate metabolic process GO:0019637 125 0.025
regulation of cell proliferation GO:0042127 105 0.025
regulation of cell migration GO:0030334 55 0.025
microtubule anchoring GO:0034453 8 0.025
modification dependent macromolecule catabolic process GO:0043632 32 0.025
carbohydrate derivative catabolic process GO:1901136 82 0.025
regulation of nucleocytoplasmic transport GO:0046822 3 0.025
myosin filament organization GO:0031033 138 0.025
mitotic spindle organization GO:0007052 81 0.024
Fly
positive regulation of protein modification process GO:0031401 29 0.024
regulation of lipid biosynthetic process GO:0046890 1 0.024
ribonucleoside triphosphate catabolic process GO:0009203 72 0.024
response to external biotic stimulus GO:0043207 101 0.024
response to other organism GO:0051707 101 0.024
pre mirna processing GO:0031054 3 0.024
meiosis i GO:0007127 19 0.024
regulation of organelle organization GO:0033043 164 0.023
Zebrafish Mouse Fly
regulation of hydrolase activity GO:0051336 45 0.023
actin filament based process GO:0030029 191 0.023
Zebrafish Mouse Fly
myosin filament assembly GO:0031034 138 0.023
protein oligomerization GO:0051259 4 0.023
positive regulation of multicellular organism growth GO:0040018 352 0.023
negative regulation of post embryonic development GO:0048581 208 0.022
nucleoside phosphate catabolic process GO:1901292 77 0.022
gene silencing by rna GO:0031047 143 0.022
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.022
negative regulation of proteasomal protein catabolic process GO:1901799 4 0.022
purine nucleoside monophosphate catabolic process GO:0009128 28 0.021
endomembrane system organization GO:0010256 22 0.021
purine nucleotide catabolic process GO:0006195 75 0.021
ribose phosphate metabolic process GO:0019693 99 0.021
negative regulation of cellular protein catabolic process GO:1903363 4 0.021
neuron projection development GO:0031175 187 0.021
Mouse Fly
response to biotic stimulus GO:0009607 101 0.021
negative regulation of organelle organization GO:0010639 20 0.021
epithelium development GO:0060429 68 0.021
Human Zebrafish Mouse Fly
actin cytoskeleton organization GO:0030036 184 0.021
Zebrafish Mouse Fly
ribonucleoside catabolic process GO:0042454 77 0.020
regulation of cell motility GO:2000145 57 0.020
regulation of anatomical structure morphogenesis GO:0022603 51 0.020
proteolysis involved in cellular protein catabolic process GO:0051603 32 0.020
dsrna fragmentation GO:0031050 10 0.020
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 4 0.020
neuron recognition GO:0008038 83 0.019
gene silencing GO:0016458 143 0.019
purine ribonucleoside metabolic process GO:0046128 92 0.019
intracellular receptor signaling pathway GO:0030522 2 0.019
purine ribonucleotide metabolic process GO:0009150 95 0.019
regulation of phosphorus metabolic process GO:0051174 81 0.019
Fly
mitotic sister chromatid segregation GO:0000070 38 0.019
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.019
posttranscriptional gene silencing by rna GO:0035194 143 0.019
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.019
negative regulation of mitotic sister chromatid segregation GO:0033048 4 0.019
cell migration GO:0016477 306 0.019
collagen and cuticulin based cuticle development GO:0040002 99 0.019
positive regulation of developmental growth GO:0048639 354 0.018
negative regulation of cellular protein metabolic process GO:0032269 27 0.018
ribosome biogenesis GO:0042254 4 0.018
notch signaling pathway GO:0007219 22 0.018
maintenance of location in cell GO:0051651 12 0.018
Fly
modification dependent protein catabolic process GO:0019941 32 0.018
regulation of cellular ketone metabolic process GO:0010565 3 0.018
cellular ketone metabolic process GO:0042180 14 0.018
cell cycle GO:0007049 526 0.018
Human Mouse Fly
ribonucleoside triphosphate metabolic process GO:0009199 87 0.018
regulation of multicellular organism growth GO:0040014 373 0.018
chromatin assembly or disassembly GO:0006333 1 0.018
sex determination GO:0007530 60 0.018
negative regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032435 4 0.018
positive regulation of molecular function GO:0044093 61 0.017
cellular amino acid metabolic process GO:0006520 15 0.017
regulation of sister chromatid segregation GO:0033045 16 0.017
regulation of organ morphogenesis GO:2000027 4 0.017
Zebrafish Fly
atp metabolic process GO:0046034 42 0.017
nuclear migration GO:0007097 54 0.017
Fly
tube morphogenesis GO:0035239 79 0.016
Zebrafish Mouse Fly
oxoacid metabolic process GO:0043436 47 0.016
regulation of catalytic activity GO:0050790 78 0.016
regulation of cellular amine metabolic process GO:0033238 0 0.016
peptidyl amino acid modification GO:0018193 58 0.016
negative regulation of mitotic metaphase anaphase transition GO:0045841 4 0.016
secretion GO:0046903 147 0.016
cognition GO:0050890 27 0.016
hermaphrodite germ line sex determination GO:0040021 48 0.016
positive regulation of neurogenesis GO:0050769 4 0.015
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.015
negative regulation of signaling GO:0023057 61 0.015
sensory organ morphogenesis GO:0090596 2 0.015
Fly
organism emergence from protective structure GO:0071684 48 0.015
rna interference GO:0016246 137 0.015
negative regulation of cellular catabolic process GO:0031330 9 0.015
phosphorylation GO:0016310 116 0.015
Human Fly
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 34 0.015
inductive cell migration GO:0040039 145 0.015
neurological system process GO:0050877 53 0.015
generation of neurons GO:0048699 235 0.015
Mouse Fly
regulation of cell death GO:0010941 65 0.015
Mouse
nucleoside monophosphate metabolic process GO:0009123 46 0.015
defense response GO:0006952 296 0.015
ubiquitin dependent protein catabolic process GO:0006511 32 0.014
organophosphate catabolic process GO:0046434 81 0.014
aromatic compound catabolic process GO:0019439 116 0.014
nucleoside phosphate metabolic process GO:0006753 108 0.014
rna 3 end processing GO:0031123 7 0.014
regulation of mitotic cell cycle GO:0007346 76 0.014
regulation of neurogenesis GO:0050767 40 0.014
Fly
cell projection assembly GO:0030031 35 0.013
Mouse
rrna processing GO:0006364 3 0.013
rrna metabolic process GO:0016072 3 0.013
dna duplex unwinding GO:0032508 3 0.013
chromatin remodeling GO:0006338 2 0.013
amine metabolic process GO:0009308 15 0.013
primary mirna processing GO:0031053 3 0.013
cellular response to organic substance GO:0071310 119 0.013
muscle tissue development GO:0060537 1 0.013
immune response GO:0006955 192 0.013
regulation of mitotic sister chromatid segregation GO:0033047 16 0.013
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 10 0.013
cell motility GO:0048870 313 0.013
dna repair GO:0006281 23 0.013
mitotic sister chromatid separation GO:0051306 13 0.013
organic acid metabolic process GO:0006082 47 0.013
single organism biosynthetic process GO:0044711 91 0.013
regulation of molecular function GO:0065009 89 0.013
ribonucleoside monophosphate metabolic process GO:0009161 45 0.013
regulation of apoptotic signaling pathway GO:2001233 1 0.013
muscle organ morphogenesis GO:0048644 4 0.013
positive regulation of signaling GO:0023056 66 0.013
membrane invagination GO:0010324 98 0.013
multicellular organism growth GO:0035264 385 0.013
nucleobase containing small molecule metabolic process GO:0055086 115 0.013
regulation of protein localization GO:0032880 50 0.013
Fly
establishment of nucleus localization GO:0040023 55 0.012
Fly
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 5 0.012
positive regulation of proteasomal protein catabolic process GO:1901800 1 0.012
neuron differentiation GO:0030182 217 0.012
Mouse Fly
purine nucleotide metabolic process GO:0006163 95 0.012
negative regulation of signal transduction GO:0009968 60 0.012
purine containing compound catabolic process GO:0072523 75 0.012
negative regulation of nuclear division GO:0051784 6 0.012
pattern specification process GO:0007389 59 0.012
Zebrafish Fly
cell projection morphogenesis GO:0048858 148 0.012
Mouse Fly
secretion by cell GO:0032940 138 0.012
positive regulation of biosynthetic process GO:0009891 109 0.012
asymmetric neuroblast division GO:0055059 8 0.012
microtubule based process GO:0007017 182 0.012
Human Zebrafish Mouse Fly
regulation of programmed cell death GO:0043067 50 0.012
Mouse
regulation of cell differentiation GO:0045595 81 0.012
Human Fly
regulation of protein ubiquitination GO:0031396 3 0.012
cellular amine metabolic process GO:0044106 15 0.011
regulation of cellular catabolic process GO:0031329 51 0.011
nucleoside catabolic process GO:0009164 78 0.011
negative regulation of cell communication GO:0010648 61 0.011
regulation of intracellular signal transduction GO:1902531 77 0.011
phagocytosis engulfment GO:0006911 98 0.011
regulation of protein modification process GO:0031399 46 0.011
Fly
response to unfolded protein GO:0006986 71 0.011
positive regulation of multicellular organismal process GO:0051240 417 0.011
regulation of cytoskeleton organization GO:0051493 41 0.011
Zebrafish Mouse Fly
spindle checkpoint GO:0031577 4 0.011
regulation of signal transduction GO:0009966 135 0.011
Fly
epithelial tube morphogenesis GO:0060562 1 0.011
Mouse
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 1 0.011
mechanosensory behavior GO:0007638 25 0.011
dna templated transcription elongation GO:0006354 1 0.011
protein transport GO:0015031 45 0.011
Fly
posttranscriptional gene silencing GO:0016441 143 0.011
synaptic growth at neuromuscular junction GO:0051124 1 0.011
positive regulation of cell migration GO:0030335 3 0.011
metaphase anaphase transition of cell cycle GO:0044784 15 0.011
atp catabolic process GO:0006200 27 0.010
ncrna metabolic process GO:0034660 14 0.010
establishment of protein localization GO:0045184 50 0.010
Fly
protein localization to organelle GO:0033365 37 0.010

let-502 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.018
nervous system disease DOID:863 0 0.016
disease of cellular proliferation DOID:14566 0 0.011