Caenorhabditis elegans

56 known processes

egl-9 (CELE_F22E12.4)

Protein EGL-9

egl-9 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
locomotion GO:0040011 1634 0.237
glycosyl compound metabolic process GO:1901657 100 0.146
ribonucleoside triphosphate metabolic process GO:0009199 87 0.145
purine nucleotide catabolic process GO:0006195 75 0.131
purine nucleoside metabolic process GO:0042278 92 0.109
embryo development GO:0009790 3052 0.107
Mouse
purine nucleoside triphosphate metabolic process GO:0009144 87 0.105
monocarboxylic acid metabolic process GO:0032787 22 0.102
phosphate containing compound metabolic process GO:0006796 232 0.102
multicellular organismal aging GO:0010259 812 0.094
nucleobase containing small molecule metabolic process GO:0055086 115 0.094
system process GO:0003008 136 0.093
cell motility GO:0048870 313 0.089
ribonucleoside triphosphate catabolic process GO:0009203 72 0.085
post embryonic development GO:0009791 2152 0.082
embryo development ending in birth or egg hatching GO:0009792 2992 0.082
Mouse
ribose phosphate metabolic process GO:0019693 99 0.081
nucleotide metabolic process GO:0009117 108 0.079
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.076
regulation of biological quality GO:0065008 741 0.076
Human
organonitrogen compound catabolic process GO:1901565 90 0.076
nucleoside triphosphate metabolic process GO:0009141 87 0.075
positive regulation of multicellular organismal process GO:0051240 417 0.074
establishment of localization GO:0051234 1171 0.071
Fly
behavior GO:0007610 527 0.071
ribonucleoside metabolic process GO:0009119 98 0.071
purine nucleotide metabolic process GO:0006163 95 0.069
purine ribonucleotide catabolic process GO:0009154 75 0.068
vesicle mediated transport GO:0016192 852 0.066
regulation of multicellular organismal process GO:0051239 726 0.065
Mouse
cell migration GO:0016477 306 0.065
purine ribonucleotide metabolic process GO:0009150 95 0.065
nucleoside metabolic process GO:0009116 99 0.064
head development GO:0060322 1 0.063
organic substance catabolic process GO:1901575 294 0.063
catabolic process GO:0009056 318 0.061
phosphorus metabolic process GO:0006793 232 0.060
positive regulation of cellular process GO:0048522 332 0.059
Fly
organ development GO:0048513 1102 0.058
Mouse Fly
purine ribonucleoside metabolic process GO:0046128 92 0.058
apoptotic process GO:0006915 478 0.055
Mouse
maintenance of location GO:0051235 580 0.055
purine nucleoside triphosphate catabolic process GO:0009146 72 0.055
nucleoside catabolic process GO:0009164 78 0.054
secretion GO:0046903 147 0.054
macromolecule localization GO:0033036 771 0.054
endocytosis GO:0006897 819 0.053
carbohydrate derivative metabolic process GO:1901135 141 0.053
lipid storage GO:0019915 565 0.053
single organism catabolic process GO:0044712 129 0.052
lipid localization GO:0010876 573 0.052
regulation of metabolic process GO:0019222 478 0.052
Human
signaling GO:0023052 401 0.051
purine containing compound metabolic process GO:0072521 95 0.050
purine nucleoside catabolic process GO:0006152 75 0.049
growth GO:0040007 562 0.049
Fly
transport GO:0006810 1093 0.049
Fly
cellular component movement GO:0006928 388 0.048
ion transport GO:0006811 113 0.048
aromatic compound catabolic process GO:0019439 116 0.048
nucleoside triphosphate catabolic process GO:0009143 72 0.048
body morphogenesis GO:0010171 620 0.047
establishment of localization in cell GO:0051649 318 0.046
Fly
cellular catabolic process GO:0044248 199 0.046
death GO:0016265 547 0.046
Mouse
localization of cell GO:0051674 313 0.046
nucleoside phosphate metabolic process GO:0006753 108 0.046
multi organism behavior GO:0051705 389 0.045
secretion by cell GO:0032940 138 0.044
aging GO:0007568 812 0.044
regulation of gene expression GO:0010468 366 0.044
Human
detection of external stimulus GO:0009581 4 0.043
programmed cell death GO:0012501 500 0.043
Mouse
carbohydrate derivative catabolic process GO:1901136 82 0.043
regulation of growth GO:0040008 409 0.043
Fly
organophosphate metabolic process GO:0019637 125 0.043
protein complex subunit organization GO:0071822 280 0.042
receptor mediated endocytosis GO:0006898 715 0.042
cell cell signaling GO:0007267 118 0.041
muscle cell differentiation GO:0042692 171 0.041
cation transport GO:0006812 78 0.040
cell death GO:0008219 547 0.040
Mouse
negative regulation of post embryonic development GO:0048581 208 0.040
cellular response to chemical stimulus GO:0070887 129 0.040
Fly
multi organism reproductive process GO:0044703 867 0.039
multi multicellular organism process GO:0044706 390 0.039
positive regulation of cell communication GO:0010647 69 0.039
ribonucleotide catabolic process GO:0009261 75 0.039
response to external stimulus GO:0009605 289 0.039
regulation of nematode larval development GO:0061062 260 0.039
cellular nitrogen compound catabolic process GO:0044270 119 0.039
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.039
purine containing compound catabolic process GO:0072523 75 0.038
organic cyclic compound catabolic process GO:1901361 119 0.038
protein complex assembly GO:0006461 186 0.038
determination of adult lifespan GO:0008340 812 0.038
ribonucleotide metabolic process GO:0009259 99 0.037
purine ribonucleoside catabolic process GO:0046130 75 0.037
response to abiotic stimulus GO:0009628 152 0.036
regulation of response to stimulus GO:0048583 243 0.036
regulation of primary metabolic process GO:0080090 292 0.036
Human
reproductive behavior GO:0019098 387 0.036
multi organism reproductive behavior GO:0044705 387 0.036
ribonucleoside catabolic process GO:0042454 77 0.035
macromolecule modification GO:0043412 218 0.035
negative regulation of multicellular organismal process GO:0051241 236 0.034
vulval development GO:0040025 333 0.034
single organism localization GO:1902578 518 0.034
Fly
regulation of phosphorus metabolic process GO:0051174 81 0.034
oxoacid metabolic process GO:0043436 47 0.034
phosphorylation GO:0016310 116 0.034
neurological system process GO:0050877 53 0.034
small molecule metabolic process GO:0044281 186 0.033
organophosphate catabolic process GO:0046434 81 0.033
cellular protein metabolic process GO:0044267 279 0.033
protein metabolic process GO:0019538 422 0.032
nucleotide catabolic process GO:0009166 77 0.032
regulation of localization GO:0032879 194 0.032
reproductive structure development GO:0048608 850 0.032
Mouse
single organism transport GO:0044765 447 0.032
Fly
single organism biosynthetic process GO:0044711 91 0.032
metal ion transport GO:0030001 49 0.032
regulation of multicellular organism growth GO:0040014 373 0.031
developmental process involved in reproduction GO:0003006 1165 0.030
Mouse
muscle structure development GO:0061061 191 0.030
Mouse
calcium mediated signaling GO:0019722 3 0.030
meiotic cell cycle GO:0051321 335 0.030
cell cycle process GO:0022402 482 0.029
positive regulation of developmental process GO:0051094 408 0.029
protein oligomerization GO:0051259 4 0.029
negative regulation of biological process GO:0048519 567 0.029
Human
macromolecular complex subunit organization GO:0043933 320 0.029
regulation of cell communication GO:0010646 176 0.029
positive regulation of growth GO:0045927 369 0.029
Fly
regulation of multicellular organismal development GO:2000026 317 0.029
Mouse
cell development GO:0048468 696 0.028
multicellular organism growth GO:0035264 385 0.028
regulation of developmental process GO:0050793 684 0.028
Mouse
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.028
post embryonic organ development GO:0048569 336 0.027
protein complex biogenesis GO:0070271 186 0.027
meiotic chromosome segregation GO:0045132 139 0.027
regulation of transport GO:0051049 91 0.027
regulation of locomotion GO:0040012 161 0.027
response to chemical GO:0042221 356 0.027
Human Fly
cellular component biogenesis GO:0044085 297 0.027
aromatic compound biosynthetic process GO:0019438 192 0.027
Human
oviposition GO:0018991 364 0.026
protein modification process GO:0036211 207 0.026
heterocycle catabolic process GO:0046700 119 0.026
organic acid metabolic process GO:0006082 47 0.026
cellular amino acid metabolic process GO:0006520 15 0.025
nucleobase containing compound metabolic process GO:0006139 406 0.025
Human
regulation of developmental growth GO:0048638 389 0.025
carboxylic acid metabolic process GO:0019752 34 0.025
glycosyl compound catabolic process GO:1901658 79 0.025
rna metabolic process GO:0016070 228 0.024
Human
regulation of signal transduction GO:0009966 135 0.024
positive regulation of response to stimulus GO:0048584 55 0.024
molting cycle GO:0042303 281 0.024
intracellular signal transduction GO:0035556 96 0.024
positive regulation of developmental growth GO:0048639 354 0.024
protein localization GO:0008104 205 0.024
hermaphrodite genitalia development GO:0040035 734 0.024
organic substance transport GO:0071702 113 0.024
Fly
genitalia development GO:0048806 741 0.023
cellular component assembly GO:0022607 293 0.023
organic substance biosynthetic process GO:1901576 323 0.023
Human
generation of neurons GO:0048699 235 0.023
regulation of hormone secretion GO:0046883 2 0.023
macromolecular complex assembly GO:0065003 193 0.023
gene expression GO:0010467 412 0.023
Human
regulation of nitrogen compound metabolic process GO:0051171 222 0.022
Human
signal transduction GO:0007165 317 0.022
neurogenesis GO:0022008 236 0.022
organonitrogen compound metabolic process GO:1901564 151 0.022
negative regulation of nematode larval development GO:0061064 208 0.022
regulation of nucleoside metabolic process GO:0009118 37 0.022
neuron projection morphogenesis GO:0048812 114 0.022
nucleoside phosphate catabolic process GO:1901292 77 0.021
positive regulation of cellular metabolic process GO:0031325 178 0.021
regulation of catalytic activity GO:0050790 78 0.021
nervous system development GO:0007399 253 0.021
developmental growth GO:0048589 412 0.021
sex differentiation GO:0007548 909 0.021
single organism reproductive process GO:0044702 1196 0.021
Mouse
regulation of macromolecule metabolic process GO:0060255 421 0.020
Human
muscle tissue development GO:0060537 1 0.020
Mouse
regulation of secretion GO:0051046 29 0.020
regulation of behavior GO:0050795 97 0.020
guanosine containing compound metabolic process GO:1901068 49 0.020
regulation of gene expression epigenetic GO:0040029 163 0.020
meiotic nuclear division GO:0007126 300 0.020
ribonucleoside monophosphate metabolic process GO:0009161 45 0.020
development of primary sexual characteristics GO:0045137 840 0.020
adult behavior GO:0030534 3 0.020
regulation of molecular function GO:0065009 89 0.020
Human
regulation of purine nucleotide metabolic process GO:1900542 37 0.019
positive regulation of biosynthetic process GO:0009891 109 0.019
regulation of signaling GO:0023051 172 0.019
negative regulation of vulval development GO:0040027 206 0.019
actin cytoskeleton organization GO:0030036 184 0.019
regulation of cellular ketone metabolic process GO:0010565 3 0.019
cell part morphogenesis GO:0032990 152 0.019
reproductive system development GO:0061458 850 0.019
Mouse
single organism organelle organization GO:1902589 501 0.019
rna biosynthetic process GO:0032774 169 0.018
Human
multicellular organismal reproductive process GO:0048609 815 0.018
membrane organization GO:0061024 135 0.018
regulation of cell cycle GO:0051726 194 0.018
striated muscle cell differentiation GO:0051146 158 0.018
nucleoside monophosphate metabolic process GO:0009123 46 0.018
positive regulation of catabolic process GO:0009896 38 0.018
protein phosphorylation GO:0006468 85 0.018
response to wounding GO:0009611 4 0.017
dauer larval development GO:0040024 92 0.017
regulation of vulval development GO:0040028 248 0.017
heterocycle biosynthetic process GO:0018130 187 0.017
Human
regulation of cellular metabolic process GO:0031323 305 0.017
Human
gamete generation GO:0007276 461 0.017
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.017
nucleobase containing compound catabolic process GO:0034655 114 0.017
response to organic substance GO:0010033 131 0.017
neuron neuron synaptic transmission GO:0007270 22 0.017
positive regulation of neurogenesis GO:0050769 4 0.016
neuron differentiation GO:0030182 217 0.016
regulation of biosynthetic process GO:0009889 189 0.016
Human
positive regulation of nucleic acid templated transcription GO:1903508 102 0.016
regulation of cellular catabolic process GO:0031329 51 0.016
atp metabolic process GO:0046034 42 0.016
inductive cell migration GO:0040039 145 0.016
regulation of cell motility GO:2000145 57 0.016
cell cycle GO:0007049 526 0.016
multicellular organismal reproductive behavior GO:0033057 384 0.016
regulation of lipid metabolic process GO:0019216 4 0.016
cellular protein modification process GO:0006464 207 0.016
biosynthetic process GO:0009058 323 0.016
Human
positive regulation of multicellular organism growth GO:0040018 352 0.015
cellular localization GO:0051641 360 0.015
Fly
phagocytosis GO:0006909 115 0.015
protein catabolic process GO:0030163 162 0.015
rna interference GO:0016246 137 0.015
meiotic cell cycle process GO:1903046 170 0.015
cellular protein complex assembly GO:0043623 178 0.015
posttranscriptional gene silencing by rna GO:0035194 143 0.015
chemical homeostasis GO:0048878 29 0.015
Human
regulation of organ morphogenesis GO:2000027 4 0.015
signal release GO:0023061 28 0.015
positive regulation of cellular catabolic process GO:0031331 35 0.015
cellular ketone metabolic process GO:0042180 14 0.015
cytoskeleton organization GO:0007010 339 0.014
cellular response to organic substance GO:0071310 119 0.014
cellular macromolecular complex assembly GO:0034622 184 0.014
organelle organization GO:0006996 783 0.014
female gamete generation GO:0007292 254 0.014
gene silencing by rna GO:0031047 143 0.014
regulation of rna metabolic process GO:0051252 173 0.014
Human
regulation of nucleotide metabolic process GO:0006140 37 0.014
myosin filament organization GO:0031033 138 0.014
embryonic morphogenesis GO:0048598 152 0.014
regulation of post embryonic development GO:0048580 260 0.014
nucleus localization GO:0051647 55 0.014
neuromuscular junction development GO:0007528 2 0.014
neuron projection development GO:0031175 187 0.014
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.014
posttranscriptional gene silencing GO:0016441 143 0.013
negative regulation of metabolic process GO:0009892 240 0.013
regulation of catabolic process GO:0009894 57 0.013
cell division GO:0051301 262 0.013
negative regulation of developmental process GO:0051093 227 0.013
cell proliferation GO:0008283 116 0.013
Mouse
cellular response to stress GO:0033554 162 0.013
Fly
purine nucleoside monophosphate metabolic process GO:0009126 43 0.013
chromosome segregation GO:0007059 180 0.013
regulation of cell migration GO:0030334 55 0.013
regulation of cellular amino acid metabolic process GO:0006521 0 0.013
intracellular receptor signaling pathway GO:0030522 2 0.012
regulation of endocytosis GO:0030100 25 0.012
regulation of intracellular signal transduction GO:1902531 77 0.012
organelle assembly GO:0070925 214 0.012
positive regulation of signal transduction GO:0009967 40 0.012
chemosensory behavior GO:0007635 33 0.012
peptidyl serine phosphorylation GO:0018105 20 0.012
posttranscriptional regulation of gene expression GO:0010608 166 0.012
homeostatic process GO:0042592 51 0.012
Human
epithelial tube morphogenesis GO:0060562 1 0.012
Fly
detection of abiotic stimulus GO:0009582 4 0.012
nucleic acid metabolic process GO:0090304 299 0.012
Human
inorganic ion transmembrane transport GO:0098660 54 0.012
ras protein signal transduction GO:0007265 31 0.012
myosin filament assembly GO:0031034 138 0.012
hormone transport GO:0009914 2 0.012
gene silencing GO:0016458 143 0.012
carboxylic acid catabolic process GO:0046395 3 0.012
negative regulation of neuron differentiation GO:0045665 4 0.012
actin filament based process GO:0030029 191 0.012
regulation of cellular carbohydrate metabolic process GO:0010675 2 0.012
organelle fission GO:0048285 363 0.012
response to temperature stimulus GO:0009266 66 0.012
purine ribonucleoside monophosphate metabolic process GO:0009167 43 0.012
positive regulation of neuron differentiation GO:0045666 4 0.012
striated muscle myosin thick filament assembly GO:0071688 138 0.011
regulation of ras protein signal transduction GO:0046578 41 0.011
response to nutrient levels GO:0031667 35 0.011
single organism behavior GO:0044708 83 0.011
purine ribonucleoside monophosphate catabolic process GO:0009169 28 0.011
positive regulation of post embryonic development GO:0048582 54 0.011
cell surface receptor signaling pathway GO:0007166 149 0.011
myofibril assembly GO:0030239 154 0.011
sensory perception GO:0007600 27 0.011
small gtpase mediated signal transduction GO:0007264 32 0.011
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.011
positive regulation of cell migration GO:0030335 3 0.011
tissue development GO:0009888 112 0.011
Mouse Fly
membrane invagination GO:0010324 98 0.011
sensory organ morphogenesis GO:0090596 2 0.011
establishment of nucleus localization GO:0040023 55 0.011
cellular macromolecule biosynthetic process GO:0034645 247 0.011
Human
organelle localization GO:0051640 127 0.011
cell projection organization GO:0030030 231 0.011
cell substrate adhesion GO:0031589 1 0.011
regulation of cellular component movement GO:0051270 62 0.011
engulfment of apoptotic cell GO:0043652 94 0.011
negative regulation of neurogenesis GO:0050768 4 0.011
negative regulation of gene expression GO:0010629 217 0.011
regulation of cellular amine metabolic process GO:0033238 0 0.011
positive regulation of nematode larval development GO:0061063 54 0.011
adult locomotory behavior GO:0008344 1 0.011
macromolecule biosynthetic process GO:0009059 250 0.011
Human
guanosine containing compound catabolic process GO:1901069 48 0.011
long term memory GO:0007616 2 0.011
positive regulation of catalytic activity GO:0043085 59 0.011
positive regulation of macromolecule metabolic process GO:0010604 149 0.011
regulation of phosphate metabolic process GO:0019220 81 0.011
cellular amine metabolic process GO:0044106 15 0.011
regulation of cellular component organization GO:0051128 248 0.010
Fly
nitrogen compound transport GO:0071705 49 0.010
positive regulation of signaling GO:0023056 66 0.010
positive regulation of cell projection organization GO:0031346 4 0.010
positive regulation of rna metabolic process GO:0051254 103 0.010
defense response GO:0006952 296 0.010
synaptic growth at neuromuscular junction GO:0051124 1 0.010
fertilization GO:0009566 63 0.010
muscle cell development GO:0055001 158 0.010
cell growth GO:0016049 44 0.010
Fly
neuromuscular process GO:0050905 1 0.010
cell projection assembly GO:0030031 35 0.010
regulation of apoptotic signaling pathway GO:2001233 1 0.010

egl-9 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.027
nervous system disease DOID:863 0 0.013
disease of metabolism DOID:0014667 0 0.012