Caenorhabditis elegans

39 known processes

map-2 (CELE_Y116A8A.9)

Protein MAP-2

map-2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development ending in birth or egg hatching GO:0009792 2992 0.680
embryo development GO:0009790 3052 0.588
organ development GO:0048513 1102 0.439
post embryonic development GO:0009791 2152 0.306
developmental process involved in reproduction GO:0003006 1165 0.262
locomotion GO:0040011 1634 0.249
gene expression GO:0010467 412 0.245
Human
reproductive structure development GO:0048608 850 0.240
chromatin modification GO:0016568 32 0.228
gonad development GO:0008406 840 0.212
regulation of gene expression GO:0010468 366 0.208
negative regulation of biological process GO:0048519 567 0.195
genitalia development GO:0048806 741 0.192
chromosome organization GO:0051276 104 0.179
meiotic chromosome segregation GO:0045132 139 0.178
dna metabolic process GO:0006259 74 0.163
gene silencing GO:0016458 143 0.154
organelle organization GO:0006996 783 0.150
meiotic cell cycle GO:0051321 335 0.147
organelle fission GO:0048285 363 0.140
meiotic cell cycle process GO:1903046 170 0.138
meiotic nuclear division GO:0007126 300 0.127
chromatin organization GO:0006325 32 0.127
cell cycle GO:0007049 526 0.127
gamete generation GO:0007276 461 0.126
regulation of gene expression epigenetic GO:0040029 163 0.113
reproductive system development GO:0061458 850 0.111
mitotic nuclear division GO:0007067 89 0.107
aging GO:0007568 812 0.106
regulation of vulval development GO:0040028 248 0.105
catabolic process GO:0009056 318 0.101
cell cycle process GO:0022402 482 0.100
macromolecule modification GO:0043412 218 0.099
Human
cellular component morphogenesis GO:0032989 318 0.099
mitotic spindle organization GO:0007052 81 0.098
macromolecule localization GO:0033036 771 0.097
protein metabolic process GO:0019538 422 0.097
single organism organelle organization GO:1902589 501 0.096
multicellular organismal aging GO:0010259 812 0.094
hermaphrodite genitalia development GO:0040035 734 0.091
multicellular organism reproduction GO:0032504 819 0.090
macromolecular complex subunit organization GO:0043933 320 0.090
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.089
negative regulation of macromolecule metabolic process GO:0010605 229 0.088
nucleic acid metabolic process GO:0090304 299 0.083
aromatic compound biosynthetic process GO:0019438 192 0.082
heterocycle biosynthetic process GO:0018130 187 0.081
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.079
molting cycle GO:0042303 281 0.078
single organism reproductive process GO:0044702 1196 0.078
regulation of metabolic process GO:0019222 478 0.076
regulation of macromolecule metabolic process GO:0060255 421 0.075
multicellular organismal reproductive process GO:0048609 815 0.072
sexual reproduction GO:0019953 546 0.071
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.070
negative regulation of gene expression GO:0010629 217 0.070
sex differentiation GO:0007548 909 0.070
posttranscriptional regulation of gene expression GO:0010608 166 0.069
rrna metabolic process GO:0016072 3 0.068
protein complex subunit organization GO:0071822 280 0.065
regulation of macromolecule biosynthetic process GO:0010556 189 0.065
post embryonic organ development GO:0048569 336 0.064
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.063
transport GO:0006810 1093 0.062
negative regulation of gene expression epigenetic GO:0045814 2 0.061
development of primary sexual characteristics GO:0045137 840 0.061
lipid localization GO:0010876 573 0.060
maintenance of location GO:0051235 580 0.060
lipid storage GO:0019915 565 0.059
nucleobase containing compound biosynthetic process GO:0034654 184 0.059
gene silencing by rna GO:0031047 143 0.059
protein modification process GO:0036211 207 0.059
Human
organic substance catabolic process GO:1901575 294 0.057
regulation of nitrogen compound metabolic process GO:0051171 222 0.057
sister chromatid segregation GO:0000819 46 0.057
cellular protein metabolic process GO:0044267 279 0.057
Human
determination of adult lifespan GO:0008340 812 0.056
death GO:0016265 547 0.055
nucleic acid templated transcription GO:0097659 169 0.054
transcription dna templated GO:0006351 168 0.053
negative regulation of metabolic process GO:0009892 240 0.053
nucleobase containing compound metabolic process GO:0006139 406 0.053
cellular biosynthetic process GO:0044249 315 0.052
vesicle mediated transport GO:0016192 852 0.051
regulation of cellular component organization GO:0051128 248 0.049
regulation of biological quality GO:0065008 741 0.049
cellular nitrogen compound biosynthetic process GO:0044271 192 0.048
negative regulation of transcription dna templated GO:0045892 53 0.048
rna metabolic process GO:0016070 228 0.047
protein complex assembly GO:0006461 186 0.046
vulval development GO:0040025 333 0.045
regulation of multicellular organismal development GO:2000026 317 0.045
behavior GO:0007610 527 0.045
cell death GO:0008219 547 0.044
cellular protein complex assembly GO:0043623 178 0.044
cellular component assembly involved in morphogenesis GO:0010927 183 0.044
multi organism reproductive process GO:0044703 867 0.044
phosphorus metabolic process GO:0006793 232 0.044
regulation of nuclear division GO:0051783 115 0.043
organic cyclic compound catabolic process GO:1901361 119 0.043
cell development GO:0048468 696 0.043
cytoskeleton organization GO:0007010 339 0.042
regulation of meiotic cell cycle GO:0051445 136 0.041
neuron projection development GO:0031175 187 0.041
regulation of rna biosynthetic process GO:2001141 165 0.041
regulation of cell cycle process GO:0010564 145 0.040
head development GO:0060322 1 0.040
regulation of rna metabolic process GO:0051252 173 0.040
cellular macromolecular complex assembly GO:0034622 184 0.040
multi organism reproductive behavior GO:0044705 387 0.040
single organism localization GO:1902578 518 0.040
growth GO:0040007 562 0.040
macromolecule catabolic process GO:0009057 202 0.039
aromatic compound catabolic process GO:0019439 116 0.039
transcription from rna polymerase ii promoter GO:0006366 149 0.039
developmental growth GO:0048589 412 0.039
body morphogenesis GO:0010171 620 0.038
negative regulation of rna biosynthetic process GO:1902679 53 0.038
regulation of nucleic acid templated transcription GO:1903506 165 0.038
regulation of multicellular organismal process GO:0051239 726 0.038
macromolecule biosynthetic process GO:0009059 250 0.038
posttranscriptional gene silencing GO:0016441 143 0.038
programmed cell death GO:0012501 500 0.038
single organism transport GO:0044765 447 0.037
regulation of mitotic cell cycle GO:0007346 76 0.037
regulation of mitosis GO:0007088 18 0.037
protein complex biogenesis GO:0070271 186 0.037
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.036
regulation of cell cycle GO:0051726 194 0.036
cellular component assembly GO:0022607 293 0.035
negative regulation of multicellular organismal process GO:0051241 236 0.035
regulation of chromosome organization GO:0033044 20 0.035
germ cell development GO:0007281 351 0.035
chromosome segregation GO:0007059 180 0.035
positive regulation of developmental growth GO:0048639 354 0.034
regulation of developmental growth GO:0048638 389 0.034
oviposition GO:0018991 364 0.034
covalent chromatin modification GO:0016569 30 0.034
regulation of organelle organization GO:0033043 164 0.033
multicellular organismal reproductive behavior GO:0033057 384 0.033
endocytosis GO:0006897 819 0.033
reproductive behavior GO:0019098 387 0.033
axon guidance GO:0007411 82 0.033
neuron projection guidance GO:0097485 82 0.033
response to wounding GO:0009611 4 0.032
phagocytosis GO:0006909 115 0.032
posttranscriptional gene silencing by rna GO:0035194 143 0.032
macromolecular complex assembly GO:0065003 193 0.032
rho protein signal transduction GO:0007266 2 0.032
cellular component movement GO:0006928 388 0.032
digestive tract development GO:0048565 122 0.032
female gamete generation GO:0007292 254 0.031
rna interference GO:0016246 137 0.031
organic cyclic compound biosynthetic process GO:1901362 195 0.031
anatomical structure formation involved in morphogenesis GO:0048646 250 0.031
apoptotic process GO:0006915 478 0.031
establishment of localization in cell GO:0051649 318 0.030
regulation of multicellular organism growth GO:0040014 373 0.030
microtubule based process GO:0007017 182 0.029
actin filament based process GO:0030029 191 0.029
positive regulation of developmental process GO:0051094 408 0.029
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.029
negative regulation of developmental process GO:0051093 227 0.029
cellular response to stress GO:0033554 162 0.029
positive regulation of neurogenesis GO:0050769 4 0.029
positive regulation of cellular process GO:0048522 332 0.029
cellular protein modification process GO:0006464 207 0.028
Human
cell projection organization GO:0030030 231 0.028
cellular component biogenesis GO:0044085 297 0.028
histone modification GO:0016570 30 0.028
negative regulation of cellular process GO:0048523 239 0.028
establishment of localization GO:0051234 1171 0.028
cellular localization GO:0051641 360 0.027
cellular response to dna damage stimulus GO:0006974 41 0.027
ribosome biogenesis GO:0042254 4 0.027
nucleobase containing compound catabolic process GO:0034655 114 0.027
regulation of post embryonic development GO:0048580 260 0.027
regulation of biosynthetic process GO:0009889 189 0.027
engulfment of apoptotic cell GO:0043652 94 0.026
regulation of developmental process GO:0050793 684 0.026
positive regulation of growth GO:0045927 369 0.026
regulation of cellular biosynthetic process GO:0031326 189 0.025
protein catabolic process GO:0030163 162 0.025
positive regulation of macromolecule metabolic process GO:0010604 149 0.025
neuron projection morphogenesis GO:0048812 114 0.024
heterocycle catabolic process GO:0046700 119 0.024
regulation of growth GO:0040008 409 0.024
regulation of cell division GO:0051302 142 0.024
pronuclear migration GO:0035046 51 0.024
negative regulation of rna metabolic process GO:0051253 53 0.024
spermatogenesis GO:0007283 41 0.023
cellular catabolic process GO:0044248 199 0.023
negative regulation of nucleic acid templated transcription GO:1903507 53 0.023
multicellular organism growth GO:0035264 385 0.023
small molecule metabolic process GO:0044281 186 0.023
ribose phosphate metabolic process GO:0019693 99 0.022
regulation of transcription dna templated GO:0006355 164 0.022
single fertilization GO:0007338 61 0.022
actin cytoskeleton organization GO:0030036 184 0.022
rna biosynthetic process GO:0032774 169 0.022
cell morphogenesis involved in differentiation GO:0000904 112 0.022
organonitrogen compound metabolic process GO:1901564 151 0.022
neuron development GO:0048666 199 0.022
rna localization GO:0006403 3 0.022
gastrulation GO:0007369 58 0.022
response to chemical GO:0042221 356 0.022
mitotic cell cycle process GO:1903047 194 0.022
negative regulation of cellular metabolic process GO:0031324 95 0.021
neuron differentiation GO:0030182 217 0.021
receptor mediated endocytosis GO:0006898 715 0.021
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.021
ribonucleoside monophosphate metabolic process GO:0009161 45 0.021
rrna processing GO:0006364 3 0.021
chromatin remodeling GO:0006338 2 0.021
fertilization GO:0009566 63 0.021
glycosyl compound metabolic process GO:1901657 100 0.020
organelle assembly GO:0070925 214 0.020
nervous system development GO:0007399 253 0.020
nucleoside metabolic process GO:0009116 99 0.020
positive regulation of multicellular organismal process GO:0051240 417 0.020
taxis GO:0042330 128 0.020
cell cycle switching mitotic to meiotic cell cycle GO:0051728 35 0.020
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.020
cell division GO:0051301 262 0.020
multi multicellular organism process GO:0044706 390 0.020
oocyte construction GO:0007308 2 0.020
cellular macromolecule biosynthetic process GO:0034645 247 0.019
biosynthetic process GO:0009058 323 0.019
regulation of bmp signaling pathway GO:0030510 3 0.019
positive regulation of multicellular organism growth GO:0040018 352 0.019
regulation of primary metabolic process GO:0080090 292 0.019
nucleoside phosphate metabolic process GO:0006753 108 0.019
striated muscle cell development GO:0055002 157 0.019
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.019
purine containing compound metabolic process GO:0072521 95 0.019
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.019
regulation of nematode larval development GO:0061062 260 0.018
positive regulation of gene expression GO:0010628 112 0.018
secretion by cell GO:0032940 138 0.018
regulation of cellular metabolic process GO:0031323 305 0.018
tube morphogenesis GO:0035239 79 0.018
myofibril assembly GO:0030239 154 0.018
myosin filament organization GO:0031033 138 0.018
embryonic morphogenesis GO:0048598 152 0.017
actomyosin structure organization GO:0031032 154 0.017
multi organism behavior GO:0051705 389 0.017
ribonucleoside metabolic process GO:0009119 98 0.017
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.017
positive regulation of cell morphogenesis involved in differentiation GO:0010770 4 0.017
positive regulation of intracellular transport GO:0032388 2 0.017
striated muscle cell differentiation GO:0051146 158 0.017
myosin filament assembly GO:0031034 138 0.017
regulation of catalytic activity GO:0050790 78 0.017
phosphate containing compound metabolic process GO:0006796 232 0.017
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.017
ribonucleoside triphosphate metabolic process GO:0009199 87 0.017
negative regulation of vulval development GO:0040027 206 0.017
organic acid metabolic process GO:0006082 47 0.016
negative regulation of nematode larval development GO:0061064 208 0.016
negative regulation of neurogenesis GO:0050768 4 0.016
response to external biotic stimulus GO:0043207 101 0.016
regulation of molecular function GO:0065009 89 0.016
inductive cell migration GO:0040039 145 0.016
bmp signaling pathway GO:0030509 3 0.016
cellular macromolecule catabolic process GO:0044265 73 0.016
microtubule based movement GO:0007018 33 0.016
neurogenesis GO:0022008 236 0.016
spindle organization GO:0007051 92 0.016
generation of neurons GO:0048699 235 0.016
organophosphate catabolic process GO:0046434 81 0.016
regulation of axon extension GO:0030516 20 0.016
carbohydrate derivative metabolic process GO:1901135 141 0.015
striated muscle myosin thick filament assembly GO:0071688 138 0.015
axon development GO:0061564 163 0.015
organophosphate metabolic process GO:0019637 125 0.015
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.015
muscle structure development GO:0061061 191 0.015
ribonucleoprotein complex assembly GO:0022618 4 0.015
positive regulation of chromosome organization GO:2001252 2 0.015
negative regulation of cellular biosynthetic process GO:0031327 65 0.015
nucleotide metabolic process GO:0009117 108 0.015
organic substance biosynthetic process GO:1901576 323 0.015
positive regulation of neuron differentiation GO:0045666 4 0.015
response to external stimulus GO:0009605 289 0.015
axon extension GO:0048675 37 0.015
positive regulation of cellular biosynthetic process GO:0031328 109 0.015
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.015
adult behavior GO:0030534 3 0.015
response to abiotic stimulus GO:0009628 152 0.015
ras protein signal transduction GO:0007265 31 0.015
regulation of cellular ketone metabolic process GO:0010565 3 0.015
oogenesis GO:0048477 229 0.015
membrane invagination GO:0010324 98 0.015
phosphorylation GO:0016310 116 0.014
tube development GO:0035295 126 0.014
hermaphrodite germ line sex determination GO:0040021 48 0.014
carboxylic acid metabolic process GO:0019752 34 0.014
single organism catabolic process GO:0044712 129 0.014
sensory organ morphogenesis GO:0090596 2 0.014
response to acid chemical GO:0001101 4 0.014
muscle cell differentiation GO:0042692 171 0.014
regulation of cytoplasmic transport GO:1903649 3 0.014
organic substance transport GO:0071702 113 0.014
negative regulation of biosynthetic process GO:0009890 65 0.014
regulation of purine nucleotide metabolic process GO:1900542 37 0.013
small gtpase mediated signal transduction GO:0007264 32 0.013
secretion GO:0046903 147 0.013
regeneration GO:0031099 4 0.013
regulation of small gtpase mediated signal transduction GO:0051056 41 0.013
regulation of neurogenesis GO:0050767 40 0.013
regulation of nucleocytoplasmic transport GO:0046822 3 0.013
cell proliferation GO:0008283 116 0.013
protein localization GO:0008104 205 0.013
regulation of meiosis GO:0040020 94 0.013
response to heat GO:0009408 50 0.013
chemotaxis GO:0006935 120 0.013
cell morphogenesis GO:0000902 163 0.013
cell projection morphogenesis GO:0048858 148 0.013
positive regulation of protein metabolic process GO:0051247 45 0.013
regulation of protein import into nucleus GO:0042306 3 0.013
neuromuscular junction development GO:0007528 2 0.013
transcription elongation from rna polymerase ii promoter GO:0006368 1 0.013
actin cytoskeleton reorganization GO:0031532 4 0.012
muscle cell development GO:0055001 158 0.012
purine ribonucleoside metabolic process GO:0046128 92 0.012
purine ribonucleotide metabolic process GO:0009150 95 0.012
digestive system development GO:0055123 122 0.012
regulation of protein targeting GO:1903533 3 0.012
male gamete generation GO:0048232 41 0.012
positive regulation of cell projection organization GO:0031346 4 0.012
carbohydrate derivative catabolic process GO:1901136 82 0.012
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.012
purine nucleoside triphosphate metabolic process GO:0009144 87 0.012
axonogenesis GO:0007409 102 0.012
response to biotic stimulus GO:0009607 101 0.012
sex determination GO:0007530 60 0.012
oocyte axis specification GO:0007309 2 0.012
collagen and cuticulin based cuticle development GO:0040002 99 0.012
membrane organization GO:0061024 135 0.012
guanosine containing compound metabolic process GO:1901068 49 0.012
regulation of ras protein signal transduction GO:0046578 41 0.012
regulation of catabolic process GO:0009894 57 0.012
immune response GO:0006955 192 0.011
purine nucleoside metabolic process GO:0042278 92 0.011
regulation of atp catabolic process GO:1903289 3 0.011
single organism signaling GO:0044700 401 0.011
Zebrafish
adult locomotory behavior GO:0008344 1 0.011
negative regulation of post embryonic development GO:0048581 208 0.011
germ line sex determination GO:0018992 51 0.011
cytokinesis GO:0000910 80 0.011
system process GO:0003008 136 0.011
nucleoside catabolic process GO:0009164 78 0.011
single organism behavior GO:0044708 83 0.011
canonical wnt signaling pathway GO:0060070 3 0.011
nucleoside phosphate catabolic process GO:1901292 77 0.011
cellular response to chemical stimulus GO:0070887 129 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 32 0.011
regulation of nucleotide catabolic process GO:0030811 35 0.011
cellular nitrogen compound catabolic process GO:0044270 119 0.011
organonitrogen compound catabolic process GO:1901565 90 0.011
nucleobase containing small molecule metabolic process GO:0055086 115 0.010
translational initiation GO:0006413 2 0.010
protein localization to endoplasmic reticulum GO:0070972 2 0.010
regulation of gtpase activity GO:0043087 30 0.010
positive regulation of neuron projection development GO:0010976 4 0.010
nucleoside monophosphate metabolic process GO:0009123 46 0.010
intracellular transport GO:0046907 77 0.010
proteasome assembly GO:0043248 1 0.010
innate immune response GO:0045087 190 0.010
organism emergence from protective structure GO:0071684 48 0.010
cellular response to abiotic stimulus GO:0071214 4 0.010
defense response to other organism GO:0098542 100 0.010
maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000466 1 0.010
cell motility GO:0048870 313 0.010

map-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.064
nervous system disease DOID:863 0 0.012
musculoskeletal system disease DOID:17 0 0.012
disease of metabolism DOID:0014667 0 0.011