Caenorhabditis elegans

15 known processes

tni-4 (CELE_W03F8.1)

Protein TNI-4

tni-4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
post embryonic development GO:0009791 2152 0.398
Worm
organelle organization GO:0006996 783 0.337
Zebrafish Worm Fly
organ development GO:0048513 1102 0.303
Mouse Worm Fly
regulation of developmental process GO:0050793 684 0.218
embryo development GO:0009790 3052 0.218
locomotion GO:0040011 1634 0.178
Worm
regulation of multicellular organismal development GO:2000026 317 0.177
cell development GO:0048468 696 0.172
Zebrafish Worm Fly
positive regulation of growth GO:0045927 369 0.168
multicellular organism reproduction GO:0032504 819 0.158
Worm
multi organism reproductive process GO:0044703 867 0.155
Worm
regulation of multicellular organismal process GO:0051239 726 0.154
Mouse
regulation of biological quality GO:0065008 741 0.146
Mouse Fly
transport GO:0006810 1093 0.140
protein metabolic process GO:0019538 422 0.121
apoptotic process GO:0006915 478 0.121
programmed cell death GO:0012501 500 0.120
cell projection organization GO:0030030 231 0.117
Worm
organic substance catabolic process GO:1901575 294 0.113
embryo development ending in birth or egg hatching GO:0009792 2992 0.112
receptor mediated endocytosis GO:0006898 715 0.111
cellular component biogenesis GO:0044085 297 0.106
Zebrafish Worm Fly
biosynthetic process GO:0009058 323 0.101
positive regulation of multicellular organismal process GO:0051240 417 0.101
single organism organelle organization GO:1902589 501 0.101
Zebrafish Worm Fly
establishment of localization GO:0051234 1171 0.099
death GO:0016265 547 0.098
signal transduction GO:0007165 317 0.097
neuron projection development GO:0031175 187 0.093
Worm
response to topologically incorrect protein GO:0035966 82 0.090
cytoskeleton organization GO:0007010 339 0.090
Zebrafish Worm Fly
endocytosis GO:0006897 819 0.089
cellular response to topologically incorrect protein GO:0035967 76 0.089
catabolic process GO:0009056 318 0.088
cell death GO:0008219 547 0.088
cellular component movement GO:0006928 388 0.087
single organism signaling GO:0044700 401 0.086
negative regulation of biological process GO:0048519 567 0.086
regulation of developmental growth GO:0048638 389 0.084
nervous system development GO:0007399 253 0.083
Worm Fly
regulation of metabolic process GO:0019222 478 0.081
cell migration GO:0016477 306 0.079
positive regulation of developmental growth GO:0048639 354 0.075
nucleobase containing compound metabolic process GO:0006139 406 0.075
macromolecule localization GO:0033036 771 0.075
developmental process involved in reproduction GO:0003006 1165 0.075
Worm
generation of neurons GO:0048699 235 0.075
Worm
developmental growth GO:0048589 412 0.075
determination of adult lifespan GO:0008340 812 0.074
multicellular organism growth GO:0035264 385 0.074
regulation of response to stimulus GO:0048583 243 0.074
Mouse
neuron development GO:0048666 199 0.073
Worm
growth GO:0040007 562 0.072
multicellular organismal aging GO:0010259 812 0.071
axon development GO:0061564 163 0.070
Worm
cell motility GO:0048870 313 0.068
cellular protein metabolic process GO:0044267 279 0.065
cell morphogenesis GO:0000902 163 0.064
Worm
multicellular organismal reproductive behavior GO:0033057 384 0.063
Worm
post embryonic organ development GO:0048569 336 0.063
chemotaxis GO:0006935 120 0.061
maintenance of location GO:0051235 580 0.060
cellular response to unfolded protein GO:0034620 71 0.060
sexual reproduction GO:0019953 546 0.059
cellular biosynthetic process GO:0044249 315 0.059
macromolecule modification GO:0043412 218 0.059
single organism transport GO:0044765 447 0.059
aging GO:0007568 812 0.058
reproductive behavior GO:0019098 387 0.057
Worm
regulation of macromolecule metabolic process GO:0060255 421 0.057
lipid localization GO:0010876 573 0.056
single organism localization GO:1902578 518 0.055
phosphorus metabolic process GO:0006793 232 0.054
cellular component assembly GO:0022607 293 0.054
Zebrafish Worm Fly
gene expression GO:0010467 412 0.054
response to chemical GO:0042221 356 0.053
positive regulation of multicellular organism growth GO:0040018 352 0.053
signaling GO:0023052 401 0.053
response to wounding GO:0009611 4 0.053
regulation of multicellular organism growth GO:0040014 373 0.052
lipid storage GO:0019915 565 0.052
vesicle mediated transport GO:0016192 852 0.050
muscle cell development GO:0055001 158 0.049
Zebrafish Worm Fly
multi organism behavior GO:0051705 389 0.048
Worm
single organism reproductive process GO:0044702 1196 0.048
Worm
regulation of catabolic process GO:0009894 57 0.048
localization of cell GO:0051674 313 0.047
protein catabolic process GO:0030163 162 0.046
regulation of growth GO:0040008 409 0.046
muscle cell differentiation GO:0042692 171 0.046
Zebrafish Worm Fly
regulation of primary metabolic process GO:0080090 292 0.045
multi organism reproductive behavior GO:0044705 387 0.045
Worm
protein modification process GO:0036211 207 0.045
organic substance biosynthetic process GO:1901576 323 0.044
neurogenesis GO:0022008 236 0.044
Worm
regulation of gene expression GO:0010468 366 0.043
single organism catabolic process GO:0044712 129 0.043
macromolecular complex subunit organization GO:0043933 320 0.042
positive regulation of developmental process GO:0051094 408 0.041
head development GO:0060322 1 0.040
organ morphogenesis GO:0009887 67 0.040
Mouse
multicellular organismal reproductive process GO:0048609 815 0.040
Worm
actin cytoskeleton organization GO:0030036 184 0.040
Zebrafish Worm Fly
gamete generation GO:0007276 461 0.040
response to abiotic stimulus GO:0009628 152 0.040
oviposition GO:0018991 364 0.040
Worm
cellular component morphogenesis GO:0032989 318 0.039
Zebrafish Worm Fly
striated muscle cell development GO:0055002 157 0.038
Zebrafish Worm Fly
anatomical structure formation involved in morphogenesis GO:0048646 250 0.038
Zebrafish Worm Fly
muscle tissue development GO:0060537 1 0.038
Mouse Fly
behavior GO:0007610 527 0.038
body morphogenesis GO:0010171 620 0.038
Worm
taxis GO:0042330 128 0.037
ion transmembrane transport GO:0034220 91 0.037
myofibril assembly GO:0030239 154 0.037
Zebrafish Worm Fly
muscle contraction GO:0006936 43 0.036
Mouse Worm
regulation of muscle system process GO:0090257 20 0.036
Mouse
multi multicellular organism process GO:0044706 390 0.036
Worm
cellular protein modification process GO:0006464 207 0.036
positive regulation of cellular process GO:0048522 332 0.036
negative regulation of gene expression GO:0010629 217 0.035
gonad development GO:0008406 840 0.034
Worm
protein complex subunit organization GO:0071822 280 0.034
negative regulation of multicellular organismal process GO:0051241 236 0.033
cell growth GO:0016049 44 0.033
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.033
organic cyclic compound catabolic process GO:1901361 119 0.033
regulation of biosynthetic process GO:0009889 189 0.032
phosphate containing compound metabolic process GO:0006796 232 0.032
regulation of cellular component organization GO:0051128 248 0.032
cellular localization GO:0051641 360 0.032
neuron recognition GO:0008038 83 0.032
cellular macromolecular complex assembly GO:0034622 184 0.031
development of primary sexual characteristics GO:0045137 840 0.031
Worm
organonitrogen compound metabolic process GO:1901564 151 0.031
neuron differentiation GO:0030182 217 0.030
Worm
feeding behavior GO:0007631 70 0.030
organelle assembly GO:0070925 214 0.030
Zebrafish Worm Fly
epithelial tube morphogenesis GO:0060562 1 0.030
regulation of cell communication GO:0010646 176 0.029
regulation of post embryonic development GO:0048580 260 0.029
positive regulation of cellular metabolic process GO:0031325 178 0.029
negative regulation of cellular process GO:0048523 239 0.028
regulation of localization GO:0032879 194 0.028
response to external stimulus GO:0009605 289 0.027
female gamete generation GO:0007292 254 0.027
protein complex assembly GO:0006461 186 0.027
negative regulation of metabolic process GO:0009892 240 0.027
epithelium development GO:0060429 68 0.027
regulation of nematode larval development GO:0061062 260 0.027
macromolecular complex assembly GO:0065003 193 0.026
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.026
positive regulation of phosphorus metabolic process GO:0010562 56 0.026
macromolecule catabolic process GO:0009057 202 0.025
posttranscriptional regulation of gene expression GO:0010608 166 0.025
eating behavior GO:0042755 59 0.025
organelle localization GO:0051640 127 0.025
regulation of behavior GO:0050795 97 0.025
negative regulation of post embryonic development GO:0048581 208 0.025
small molecule metabolic process GO:0044281 186 0.025
phosphorylation GO:0016310 116 0.025
protein complex biogenesis GO:0070271 186 0.025
tissue development GO:0009888 112 0.025
Mouse Fly
regulation of cellular metabolic process GO:0031323 305 0.024
regulation of atp catabolic process GO:1903289 3 0.024
genitalia development GO:0048806 741 0.024
Worm
germ cell development GO:0007281 351 0.024
cell division GO:0051301 262 0.024
cellular response to organic substance GO:0071310 119 0.024
er nucleus signaling pathway GO:0006984 66 0.024
establishment of localization in cell GO:0051649 318 0.023
nucleic acid metabolic process GO:0090304 299 0.023
hermaphrodite genitalia development GO:0040035 734 0.023
Worm
cellular catabolic process GO:0044248 199 0.023
negative regulation of macromolecule metabolic process GO:0010605 229 0.023
regulation of cellular component movement GO:0051270 62 0.023
negative regulation of vulval development GO:0040027 206 0.022
cell recognition GO:0008037 85 0.022
negative regulation of nematode larval development GO:0061064 208 0.022
cellular protein complex assembly GO:0043623 178 0.022
ribonucleotide catabolic process GO:0009261 75 0.022
cellular component assembly involved in morphogenesis GO:0010927 183 0.021
Zebrafish Worm Fly
somatic muscle development GO:0007525 1 0.021
vulval development GO:0040025 333 0.021
pharyngeal pumping GO:0043050 58 0.021
negative regulation of developmental process GO:0051093 227 0.021
cellular response to chemical stimulus GO:0070887 129 0.021
nuclear migration GO:0007097 54 0.020
regulation of phosphate metabolic process GO:0019220 81 0.020
response to temperature stimulus GO:0009266 66 0.020
nucleoside metabolic process GO:0009116 99 0.020
regulation of cell death GO:0010941 65 0.020
regulation of vulval development GO:0040028 248 0.020
actin filament based process GO:0030029 191 0.019
Zebrafish Worm Fly
positive regulation of metabolic process GO:0009893 187 0.019
reproductive structure development GO:0048608 850 0.019
Worm
cell part morphogenesis GO:0032990 152 0.019
Worm
regulation of apoptotic signaling pathway GO:2001233 1 0.019
positive regulation of cell migration GO:0030335 3 0.018
heterocycle catabolic process GO:0046700 119 0.018
protein localization GO:0008104 205 0.018
organic substance transport GO:0071702 113 0.018
embryonic morphogenesis GO:0048598 152 0.018
cell morphogenesis involved in differentiation GO:0000904 112 0.018
Worm
intracellular signal transduction GO:0035556 96 0.018
molting cycle GO:0042303 281 0.018
cellular macromolecule biosynthetic process GO:0034645 247 0.017
muscle system process GO:0003012 43 0.017
Mouse Worm
rna biosynthetic process GO:0032774 169 0.017
regulation of system process GO:0044057 27 0.017
Mouse
secretion by cell GO:0032940 138 0.017
actomyosin structure organization GO:0031032 154 0.017
Zebrafish Worm Fly
cellular nitrogen compound biosynthetic process GO:0044271 192 0.017
regulation of nitrogen compound metabolic process GO:0051171 222 0.017
establishment of organelle localization GO:0051656 123 0.016
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.016
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.016
regulation of cellular biosynthetic process GO:0031326 189 0.016
regulation of organelle organization GO:0033043 164 0.016
endoplasmic reticulum unfolded protein response GO:0030968 66 0.016
striated muscle myosin thick filament assembly GO:0071688 138 0.016
regulation of molecular function GO:0065009 89 0.016
muscle structure development GO:0061061 191 0.016
Zebrafish Mouse Worm Fly
dna metabolic process GO:0006259 74 0.016
striated muscle cell differentiation GO:0051146 158 0.016
Zebrafish Worm Fly
nucleotide metabolic process GO:0009117 108 0.016
nucleoside phosphate metabolic process GO:0006753 108 0.015
response to organic substance GO:0010033 131 0.015
regulation of hydrolase activity GO:0051336 45 0.015
organonitrogen compound catabolic process GO:1901565 90 0.015
macromolecule biosynthetic process GO:0009059 250 0.015
regulation of signal transduction GO:0009966 135 0.015
transmembrane transport GO:0055085 110 0.015
monovalent inorganic cation transport GO:0015672 33 0.015
myosin filament organization GO:0031033 138 0.015
carbohydrate derivative metabolic process GO:1901135 141 0.015
ribonucleotide metabolic process GO:0009259 99 0.015
cell cycle process GO:0022402 482 0.015
nucleobase containing small molecule metabolic process GO:0055086 115 0.015
mitochondrion organization GO:0007005 20 0.014
myosin filament assembly GO:0031034 138 0.014
meiotic cell cycle process GO:1903046 170 0.014
sex differentiation GO:0007548 909 0.014
Worm
skeletal muscle thin filament assembly GO:0030240 3 0.014
ribonucleoside triphosphate catabolic process GO:0009203 72 0.014
inductive cell migration GO:0040039 145 0.014
regulation of cellular protein metabolic process GO:0032268 75 0.014
meiotic cell cycle GO:0051321 335 0.014
sensory organ morphogenesis GO:0090596 2 0.014
negative regulation of response to stimulus GO:0048585 73 0.014
axonal fasciculation GO:0007413 79 0.013
regulation of programmed cell death GO:0043067 50 0.013
proteolysis GO:0006508 61 0.013
sarcomere organization GO:0045214 10 0.013
Worm Fly
negative regulation of signaling GO:0023057 61 0.013
cell surface receptor signaling pathway GO:0007166 149 0.013
muscle organ morphogenesis GO:0048644 4 0.013
Mouse
nucleobase containing compound catabolic process GO:0034655 114 0.013
phagocytosis GO:0006909 115 0.013
protein oligomerization GO:0051259 4 0.013
secretion GO:0046903 147 0.013
glycosyl compound catabolic process GO:1901658 79 0.013
regulation of multi organism process GO:0043900 69 0.013
system process GO:0003008 136 0.012
Mouse Worm Fly
cellular amino acid metabolic process GO:0006520 15 0.012
response to anesthetic GO:0072347 1 0.012
regulation of atpase activity GO:0043462 3 0.012
cellular response to growth factor stimulus GO:0071363 18 0.012
response to oxygen levels GO:0070482 22 0.012
regulation of anatomical structure morphogenesis GO:0022603 51 0.012
cellular nitrogen compound catabolic process GO:0044270 119 0.012
response to heat GO:0009408 50 0.012
skeletal muscle organ development GO:0060538 3 0.012
Fly
ion transport GO:0006811 113 0.012
tube development GO:0035295 126 0.012
organophosphate catabolic process GO:0046434 81 0.012
nucleoside triphosphate catabolic process GO:0009143 72 0.012
organic cyclic compound biosynthetic process GO:1901362 195 0.012
cellular response to stress GO:0033554 162 0.012
heterocycle biosynthetic process GO:0018130 187 0.012
gene silencing GO:0016458 143 0.012
cell cycle GO:0007049 526 0.012
purine ribonucleotide catabolic process GO:0009154 75 0.011
neurological system process GO:0050877 53 0.011
Mouse
nucleoside phosphate catabolic process GO:1901292 77 0.011
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.011
single organism biosynthetic process GO:0044711 91 0.011
regulation of locomotion GO:0040012 161 0.011
purine nucleoside catabolic process GO:0006152 75 0.011
regulation of rna metabolic process GO:0051252 173 0.011
neuromuscular junction development GO:0007528 2 0.011
gene silencing by rna GO:0031047 143 0.011
organelle fission GO:0048285 363 0.011
Fly
response to other organism GO:0051707 101 0.011
positive regulation of locomotion GO:0040017 42 0.011
excretion GO:0007588 49 0.011
Worm
ribonucleoside monophosphate metabolic process GO:0009161 45 0.010
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.010
posttranscriptional gene silencing GO:0016441 143 0.010
protein phosphorylation GO:0006468 85 0.010
multicellular organismal movement GO:0050879 2 0.010
regulation of gene expression epigenetic GO:0040029 163 0.010
purine ribonucleoside catabolic process GO:0046130 75 0.010
cell projection morphogenesis GO:0048858 148 0.010
Worm
membrane invagination GO:0010324 98 0.010
regulation of muscle contraction GO:0006937 20 0.010
Mouse
aromatic compound catabolic process GO:0019439 116 0.010

tni-4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.038
neuromuscular disease DOID:440 0 0.023
charcot marie tooth disease type 2 DOID:0050539 0 0.023
charcot marie tooth disease DOID:10595 0 0.023
nervous system disease DOID:863 0 0.023
neuropathy DOID:870 0 0.023
myopathy DOID:423 0 0.015
muscular disease DOID:0080000 0 0.015
heart disease DOID:114 0 0.015
cardiomyopathy DOID:0050700 0 0.015
cardiovascular system disease DOID:1287 0 0.015
musculoskeletal system disease DOID:17 0 0.015
muscle tissue disease DOID:66 0 0.015