Caenorhabditis elegans

33 known processes

pde-1 (CELE_T04D3.3)

Protein PDE-1

pde-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
establishment of localization GO:0051234 1171 0.331
transport GO:0006810 1093 0.196
embryo development GO:0009790 3052 0.162
system process GO:0003008 136 0.145
single organism localization GO:1902578 518 0.136
regulation of multicellular organismal process GO:0051239 726 0.128
regulation of biological quality GO:0065008 741 0.120
post embryonic development GO:0009791 2152 0.119
body morphogenesis GO:0010171 620 0.116
regulation of metabolic process GO:0019222 478 0.109
organ development GO:0048513 1102 0.104
developmental process involved in reproduction GO:0003006 1165 0.104
macromolecule localization GO:0033036 771 0.097
sex differentiation GO:0007548 909 0.096
locomotion GO:0040011 1634 0.096
regulation of developmental process GO:0050793 684 0.094
single organism transport GO:0044765 447 0.094
gene expression GO:0010467 412 0.093
cellular localization GO:0051641 360 0.088
secretion GO:0046903 147 0.087
regulation of response to stimulus GO:0048583 243 0.086
biosynthetic process GO:0009058 323 0.086
cell cell signaling GO:0007267 118 0.083
determination of adult lifespan GO:0008340 812 0.082
regulation of multicellular organismal development GO:2000026 317 0.080
vesicle mediated transport GO:0016192 852 0.079
regulation of gene expression GO:0010468 366 0.079
behavior GO:0007610 527 0.078
multicellular organismal aging GO:0010259 812 0.076
lipid localization GO:0010876 573 0.073
embryo development ending in birth or egg hatching GO:0009792 2992 0.073
cation transport GO:0006812 78 0.070
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.068
cellular biosynthetic process GO:0044249 315 0.068
maintenance of location GO:0051235 580 0.067
growth GO:0040007 562 0.066
organic cyclic compound biosynthetic process GO:1901362 195 0.065
regulation of developmental growth GO:0048638 389 0.064
endocytosis GO:0006897 819 0.064
development of primary sexual characteristics GO:0045137 840 0.063
organelle localization GO:0051640 127 0.062
multicellular organism growth GO:0035264 385 0.062
lipid storage GO:0019915 565 0.061
single organism reproductive process GO:0044702 1196 0.059
multi organism reproductive process GO:0044703 867 0.058
nucleobase containing compound metabolic process GO:0006139 406 0.058
multicellular organism reproduction GO:0032504 819 0.057
regulation of cellular biosynthetic process GO:0031326 189 0.057
regulation of localization GO:0032879 194 0.055
regulation of growth GO:0040008 409 0.055
gonad development GO:0008406 840 0.053
muscle tissue development GO:0060537 1 0.053
reproductive structure development GO:0048608 850 0.053
cell fate commitment GO:0045165 139 0.052
heterocycle biosynthetic process GO:0018130 187 0.052
regulation of biosynthetic process GO:0009889 189 0.050
cellular macromolecule biosynthetic process GO:0034645 247 0.050
regulation of macromolecule metabolic process GO:0060255 421 0.049
head development GO:0060322 1 0.049
receptor mediated endocytosis GO:0006898 715 0.049
nucleic acid templated transcription GO:0097659 169 0.049
transcription dna templated GO:0006351 168 0.048
cell cycle process GO:0022402 482 0.048
aging GO:0007568 812 0.048
cell death GO:0008219 547 0.048
single organism behavior GO:0044708 83 0.047
catabolic process GO:0009056 318 0.047
reproductive system development GO:0061458 850 0.047
positive regulation of cellular process GO:0048522 332 0.047
ion transport GO:0006811 113 0.046
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.046
macromolecular complex subunit organization GO:0043933 320 0.046
positive regulation of developmental process GO:0051094 408 0.046
protein metabolic process GO:0019538 422 0.045
cytoskeleton organization GO:0007010 339 0.044
response to mechanical stimulus GO:0009612 28 0.044
response to abiotic stimulus GO:0009628 152 0.044
nucleic acid metabolic process GO:0090304 299 0.043
developmental growth GO:0048589 412 0.042
regulation of neurotransmitter levels GO:0001505 36 0.041
organelle organization GO:0006996 783 0.041
sexual reproduction GO:0019953 546 0.040
establishment of organelle localization GO:0051656 123 0.040
establishment of localization in cell GO:0051649 318 0.039
nervous system development GO:0007399 253 0.039
negative regulation of gene expression GO:0010629 217 0.039
multi multicellular organism process GO:0044706 390 0.039
regulation of nitrogen compound metabolic process GO:0051171 222 0.038
macromolecule biosynthetic process GO:0009059 250 0.038
positive regulation of developmental growth GO:0048639 354 0.038
regulation of multicellular organism growth GO:0040014 373 0.038
negative regulation of biological process GO:0048519 567 0.038
organic substance biosynthetic process GO:1901576 323 0.038
regulation of signaling GO:0023051 172 0.037
negative regulation of multicellular organismal process GO:0051241 236 0.036
cellular nitrogen compound biosynthetic process GO:0044271 192 0.036
cellular component movement GO:0006928 388 0.036
cell development GO:0048468 696 0.036
eating behavior GO:0042755 59 0.036
sensory organ morphogenesis GO:0090596 2 0.036
regulation of cell differentiation GO:0045595 81 0.035
protein complex subunit organization GO:0071822 280 0.035
cellular component assembly GO:0022607 293 0.034
organ morphogenesis GO:0009887 67 0.034
positive regulation of growth GO:0045927 369 0.034
regulation of cell communication GO:0010646 176 0.034
axon development GO:0061564 163 0.033
transcription from rna polymerase ii promoter GO:0006366 149 0.033
synaptic transmission GO:0007268 106 0.033
protein catabolic process GO:0030163 162 0.033
negative regulation of developmental process GO:0051093 227 0.033
regulation of locomotion GO:0040012 161 0.033
regulation of cellular metabolic process GO:0031323 305 0.032
cellular component biogenesis GO:0044085 297 0.032
cell cycle GO:0007049 526 0.032
macromolecule catabolic process GO:0009057 202 0.031
negative regulation of metabolic process GO:0009892 240 0.031
anatomical structure formation involved in morphogenesis GO:0048646 250 0.031
single organism signaling GO:0044700 401 0.031
aromatic compound biosynthetic process GO:0019438 192 0.031
ion transmembrane transport GO:0034220 91 0.031
regulation of pharyngeal pumping GO:0043051 36 0.031
positive regulation of multicellular organismal process GO:0051240 417 0.031
feeding behavior GO:0007631 70 0.030
cell division GO:0051301 262 0.030
neurotransmitter secretion GO:0007269 26 0.030
signaling GO:0023052 401 0.030
positive regulation of multicellular organism growth GO:0040018 352 0.030
single organism organelle organization GO:1902589 501 0.030
cellular component morphogenesis GO:0032989 318 0.030
protein complex biogenesis GO:0070271 186 0.030
fertilization GO:0009566 63 0.029
rna metabolic process GO:0016070 228 0.029
genitalia development GO:0048806 741 0.028
neuron development GO:0048666 199 0.028
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.028
negative regulation of macromolecule metabolic process GO:0010605 229 0.028
regulation of primary metabolic process GO:0080090 292 0.028
muscle cell differentiation GO:0042692 171 0.027
death GO:0016265 547 0.027
macromolecular complex assembly GO:0065003 193 0.027
regulation of nucleic acid templated transcription GO:1903506 165 0.027
striated muscle cell differentiation GO:0051146 158 0.026
neurotransmitter transport GO:0006836 32 0.026
small molecule metabolic process GO:0044281 186 0.026
neuron projection development GO:0031175 187 0.026
muscle cell development GO:0055001 158 0.026
organic substance catabolic process GO:1901575 294 0.026
cell surface receptor signaling pathway GO:0007166 149 0.025
positive regulation of neurogenesis GO:0050769 4 0.025
cell migration GO:0016477 306 0.025
positive regulation of neuron differentiation GO:0045666 4 0.025
g protein coupled receptor signaling pathway GO:0007186 46 0.025
oviposition GO:0018991 364 0.024
regulation of rna biosynthetic process GO:2001141 165 0.024
negative regulation of cellular process GO:0048523 239 0.024
embryonic morphogenesis GO:0048598 152 0.024
multi organism behavior GO:0051705 389 0.024
regulation of molecular function GO:0065009 89 0.024
localization of cell GO:0051674 313 0.024
cellular macromolecular complex assembly GO:0034622 184 0.024
regulation of intracellular signal transduction GO:1902531 77 0.023
protein complex assembly GO:0006461 186 0.023
signal transduction GO:0007165 317 0.023
regulation of epithelial cell proliferation GO:0050678 1 0.023
cation transmembrane transport GO:0098655 59 0.023
muscle structure development GO:0061061 191 0.023
secretion by cell GO:0032940 138 0.023
regulation of catalytic activity GO:0050790 78 0.023
negative regulation of post embryonic development GO:0048581 208 0.022
regulation of macromolecule biosynthetic process GO:0010556 189 0.022
tube development GO:0035295 126 0.022
rna biosynthetic process GO:0032774 169 0.022
generation of neurons GO:0048699 235 0.022
regulation of post embryonic development GO:0048580 260 0.022
mitotic cell cycle process GO:1903047 194 0.021
regulation of behavior GO:0050795 97 0.021
neurogenesis GO:0022008 236 0.021
regulation of transcription dna templated GO:0006355 164 0.021
phosphorus metabolic process GO:0006793 232 0.021
negative regulation of biosynthetic process GO:0009890 65 0.021
cellular protein complex assembly GO:0043623 178 0.021
neurological system process GO:0050877 53 0.021
heterocycle catabolic process GO:0046700 119 0.021
regulation of gene expression epigenetic GO:0040029 163 0.020
organonitrogen compound metabolic process GO:1901564 151 0.020
aromatic compound catabolic process GO:0019439 116 0.020
positive regulation of cellular metabolic process GO:0031325 178 0.020
reproductive behavior GO:0019098 387 0.020
neuron projection morphogenesis GO:0048812 114 0.020
response to external stimulus GO:0009605 289 0.020
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.019
establishment of spindle localization GO:0051293 51 0.019
actomyosin structure organization GO:0031032 154 0.019
purine ribonucleoside catabolic process GO:0046130 75 0.019
cell motility GO:0048870 313 0.019
multi organism reproductive behavior GO:0044705 387 0.019
negative regulation of cellular biosynthetic process GO:0031327 65 0.019
tissue morphogenesis GO:0048729 65 0.019
positive regulation of gtp catabolic process GO:0033126 28 0.019
skeletal muscle organ development GO:0060538 3 0.019
metal ion transport GO:0030001 49 0.018
organonitrogen compound catabolic process GO:1901565 90 0.018
regulation of transport GO:0051049 91 0.018
transmembrane transport GO:0055085 110 0.018
protein localization GO:0008104 205 0.018
regulation of feeding behavior GO:0060259 38 0.018
organelle assembly GO:0070925 214 0.018
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.018
regulation of cell fate specification GO:0042659 22 0.018
striated muscle myosin thick filament assembly GO:0071688 138 0.018
muscle contraction GO:0006936 43 0.018
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.018
macromolecule modification GO:0043412 218 0.017
epithelial tube morphogenesis GO:0060562 1 0.017
posttranscriptional regulation of gene expression GO:0010608 166 0.017
response to wounding GO:0009611 4 0.017
tissue development GO:0009888 112 0.017
positive regulation of signaling GO:0023056 66 0.017
cellular protein metabolic process GO:0044267 279 0.017
organic substance transport GO:0071702 113 0.017
nucleobase containing compound biosynthetic process GO:0034654 184 0.017
positive regulation of neurotransmitter transport GO:0051590 11 0.017
cellular nitrogen compound catabolic process GO:0044270 119 0.017
regulation of cellular component organization GO:0051128 248 0.017
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.017
cell proliferation GO:0008283 116 0.017
protein modification process GO:0036211 207 0.017
cellular response to abiotic stimulus GO:0071214 4 0.016
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.016
detection of external stimulus GO:0009581 4 0.016
small gtpase mediated signal transduction GO:0007264 32 0.016
pharyngeal pumping GO:0043050 58 0.016
germ cell development GO:0007281 351 0.016
establishment of mitotic spindle localization GO:0040001 41 0.016
microtubule based process GO:0007017 182 0.016
positive regulation of cell morphogenesis involved in differentiation GO:0010770 4 0.016
post embryonic organ development GO:0048569 336 0.016
negative regulation of cell morphogenesis involved in differentiation GO:0010771 2 0.015
membrane organization GO:0061024 135 0.015
negative regulation of rna metabolic process GO:0051253 53 0.015
regulation of organelle organization GO:0033043 164 0.015
mitotic spindle organization GO:0007052 81 0.015
nuclear migration GO:0007097 54 0.015
establishment of protein localization to membrane GO:0090150 3 0.015
regulation of cell proliferation GO:0042127 105 0.015
gamete generation GO:0007276 461 0.015
regulation of cell cycle GO:0051726 194 0.015
single organism catabolic process GO:0044712 129 0.015
cell morphogenesis GO:0000902 163 0.015
positive regulation of rna biosynthetic process GO:1902680 102 0.015
regulation of purine nucleotide catabolic process GO:0033121 35 0.015
negative regulation of nucleic acid templated transcription GO:1903507 53 0.015
spindle localization GO:0051653 51 0.015
cellular protein modification process GO:0006464 207 0.015
regulation of nematode larval development GO:0061062 260 0.015
striated muscle cell development GO:0055002 157 0.015
ribonucleoprotein complex assembly GO:0022618 4 0.015
purine nucleoside triphosphate catabolic process GO:0009146 72 0.015
positive regulation of metabolic process GO:0009893 187 0.015
vulval development GO:0040025 333 0.015
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.015
neuromuscular junction development GO:0007528 2 0.015
inorganic ion transmembrane transport GO:0098660 54 0.014
regulation of mitotic cell cycle GO:0007346 76 0.014
positive regulation of transcription dna templated GO:0045893 102 0.014
nucleoside metabolic process GO:0009116 99 0.014
myosin filament organization GO:0031033 138 0.014
positive regulation of neuron projection development GO:0010976 4 0.014
molting cycle GO:0042303 281 0.014
regulation of acetylcholine secretion neurotransmission GO:0014056 9 0.014
organelle fission GO:0048285 363 0.014
regulation of neurotransmitter transport GO:0051588 16 0.014
actin filament based process GO:0030029 191 0.014
positive regulation of ras gtpase activity GO:0032320 19 0.014
organic cyclic compound catabolic process GO:1901361 119 0.014
cell type specific apoptotic process GO:0097285 4 0.014
positive regulation of transport GO:0051050 32 0.014
adult behavior GO:0030534 3 0.014
nucleoside catabolic process GO:0009164 78 0.014
programmed cell death GO:0012501 500 0.014
myofibril assembly GO:0030239 154 0.014
regulation of cellular ketone metabolic process GO:0010565 3 0.014
ribosome biogenesis GO:0042254 4 0.014
adult locomotory behavior GO:0008344 1 0.013
regulation of neurotransmitter secretion GO:0046928 16 0.013
regulation of signal transduction GO:0009966 135 0.013
cellular amine metabolic process GO:0044106 15 0.013
myosin filament assembly GO:0031034 138 0.013
positive regulation of cell communication GO:0010647 69 0.013
multicellular organismal reproductive behavior GO:0033057 384 0.013
pattern specification process GO:0007389 59 0.013
monovalent inorganic cation transport GO:0015672 33 0.013
regulation of synaptic transmission GO:0050804 34 0.013
nucleus localization GO:0051647 55 0.013
negative regulation of cellular metabolic process GO:0031324 95 0.013
chemotaxis GO:0006935 120 0.013
protein oligomerization GO:0051259 4 0.013
phosphate containing compound metabolic process GO:0006796 232 0.013
regulation of cellular amine metabolic process GO:0033238 0 0.013
glycosyl compound catabolic process GO:1901658 79 0.013
purine containing compound metabolic process GO:0072521 95 0.013
neuron recognition GO:0008038 83 0.013
gtp metabolic process GO:0046039 46 0.013
intracellular transport GO:0046907 77 0.013
epithelial cell proliferation GO:0050673 1 0.013
signal release GO:0023061 28 0.013
organophosphate catabolic process GO:0046434 81 0.013
positive regulation of molecular function GO:0044093 61 0.013
regulation of rna metabolic process GO:0051252 173 0.013
regulation of anatomical structure morphogenesis GO:0022603 51 0.012
nucleoside phosphate catabolic process GO:1901292 77 0.012
nucleotide catabolic process GO:0009166 77 0.012
purine nucleoside triphosphate metabolic process GO:0009144 87 0.012
establishment of nucleus localization GO:0040023 55 0.012
neuron differentiation GO:0030182 217 0.012
amine metabolic process GO:0009308 15 0.012
regulation of cell division GO:0051302 142 0.012
phagocytosis GO:0006909 115 0.012
response to chemical GO:0042221 356 0.012
regulation of cellular amino acid metabolic process GO:0006521 0 0.012
regulation of cellular localization GO:0060341 42 0.012
actin cytoskeleton organization GO:0030036 184 0.012
regulation of oviposition GO:0046662 43 0.012
regulation of apoptotic signaling pathway GO:2001233 1 0.012
positive regulation of macromolecule metabolic process GO:0010604 149 0.012
epithelium development GO:0060429 68 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.012
cellular amino acid metabolic process GO:0006520 15 0.012
phosphorylation GO:0016310 116 0.012
cellular catabolic process GO:0044248 199 0.012
positive regulation of cell projection organization GO:0031346 4 0.011
regulation of epithelial cell differentiation GO:0030856 4 0.011
apoptotic process GO:0006915 478 0.011
multicellular organismal reproductive process GO:0048609 815 0.011
nucleobase containing compound catabolic process GO:0034655 114 0.011
dna metabolic process GO:0006259 74 0.011
negative regulation of neurogenesis GO:0050768 4 0.011
positive regulation of cell migration GO:0030335 3 0.011
positive regulation of synaptic transmission GO:0050806 24 0.011
carbohydrate derivative metabolic process GO:1901135 141 0.011
cell recognition GO:0008037 85 0.011
nitrogen compound transport GO:0071705 49 0.011
mitotic nuclear division GO:0007067 89 0.011
purine ribonucleotide catabolic process GO:0009154 75 0.011
regulation of meiotic cell cycle GO:0051445 136 0.011
hormone transport GO:0009914 2 0.011
mechanosensory behavior GO:0007638 25 0.011
negative regulation of rna biosynthetic process GO:1902679 53 0.011
regulation of vulval development GO:0040028 248 0.011
purine ribonucleoside metabolic process GO:0046128 92 0.011
gene silencing by rna GO:0031047 143 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.011
positive regulation of gene expression GO:0010628 112 0.011
actin cytoskeleton reorganization GO:0031532 4 0.011
lipid metabolic process GO:0006629 77 0.011
ribose phosphate metabolic process GO:0019693 99 0.011
positive regulation of rna metabolic process GO:0051254 103 0.010
regulation of cell morphogenesis involved in differentiation GO:0010769 29 0.010
regulation of phosphate metabolic process GO:0019220 81 0.010
regulation of cellular component size GO:0032535 40 0.010
gene silencing GO:0016458 143 0.010
regulation of secretion GO:0051046 29 0.010
positive regulation of biosynthetic process GO:0009891 109 0.010
gtp catabolic process GO:0006184 46 0.010
purine nucleotide catabolic process GO:0006195 75 0.010
posttranscriptional gene silencing by rna GO:0035194 143 0.010
regulation of cell morphogenesis GO:0022604 40 0.010
protein phosphorylation GO:0006468 85 0.010
establishment of synaptic vesicle localization GO:0097480 21 0.010
rna interference GO:0016246 137 0.010
hormone metabolic process GO:0042445 3 0.010
tube morphogenesis GO:0035239 79 0.010

pde-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.028
disease of cellular proliferation DOID:14566 0 0.017
musculoskeletal system disease DOID:17 0 0.015
cancer DOID:162 0 0.012
nervous system disease DOID:863 0 0.011