Caenorhabditis elegans

10 known processes

sip-1 (CELE_F43D9.4)

Protein SIP-1

sip-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development ending in birth or egg hatching GO:0009792 2992 0.746
embryo development GO:0009790 3052 0.561
multicellular organism reproduction GO:0032504 819 0.508
multi organism reproductive process GO:0044703 867 0.437
organelle organization GO:0006996 783 0.400
locomotion GO:0040011 1634 0.395
cell cycle process GO:0022402 482 0.322
multicellular organismal reproductive process GO:0048609 815 0.305
oviposition GO:0018991 364 0.297
hermaphrodite genitalia development GO:0040035 734 0.288
cell division GO:0051301 262 0.250
multicellular organismal reproductive behavior GO:0033057 384 0.249
gamete generation GO:0007276 461 0.248
multi organism reproductive behavior GO:0044705 387 0.219
single organism organelle organization GO:1902589 501 0.199
behavior GO:0007610 527 0.188
regulation of developmental process GO:0050793 684 0.182
sexual reproduction GO:0019953 546 0.182
mitotic cell cycle process GO:1903047 194 0.181
post embryonic development GO:0009791 2152 0.179
Worm
regulation of biological quality GO:0065008 741 0.176
cellular component movement GO:0006928 388 0.172
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.171
cellular localization GO:0051641 360 0.164
organ development GO:0048513 1102 0.159
cell cycle GO:0007049 526 0.146
immune response GO:0006955 192 0.145
multi multicellular organism process GO:0044706 390 0.142
single organism reproductive process GO:0044702 1196 0.140
developmental process involved in reproduction GO:0003006 1165 0.140
reproductive behavior GO:0019098 387 0.137
multi organism behavior GO:0051705 389 0.137
macromolecular complex subunit organization GO:0043933 320 0.134
macromolecule modification GO:0043412 218 0.128
regulation of signal transduction GO:0009966 135 0.126
response to chemical GO:0042221 356 0.126
Worm
cell migration GO:0016477 306 0.125
chromatin organization GO:0006325 32 0.122
cell motility GO:0048870 313 0.120
cell surface receptor signaling pathway GO:0007166 149 0.116
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.113
anatomical structure formation involved in morphogenesis GO:0048646 250 0.110
regulation of multicellular organismal process GO:0051239 726 0.109
development of primary sexual characteristics GO:0045137 840 0.108
macromolecule localization GO:0033036 771 0.106
organelle localization GO:0051640 127 0.106
regulation of macromolecule metabolic process GO:0060255 421 0.104
cell development GO:0048468 696 0.103
cellular protein metabolic process GO:0044267 279 0.101
regulation of organelle organization GO:0033043 164 0.101
reproductive system development GO:0061458 850 0.100
positive regulation of cellular process GO:0048522 332 0.097
protein complex subunit organization GO:0071822 280 0.097
histone modification GO:0016570 30 0.095
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.092
nervous system development GO:0007399 253 0.092
germ cell development GO:0007281 351 0.091
body morphogenesis GO:0010171 620 0.091
chromatin modification GO:0016568 32 0.091
cytokinesis GO:0000910 80 0.089
neuron differentiation GO:0030182 217 0.089
genitalia development GO:0048806 741 0.082
regulation of nucleic acid templated transcription GO:1903506 165 0.082
meiotic cell cycle GO:0051321 335 0.081
lipid localization GO:0010876 573 0.074
localization of cell GO:0051674 313 0.074
regulation of nematode larval development GO:0061062 260 0.074
maintenance of location GO:0051235 580 0.072
lipid storage GO:0019915 565 0.070
female gamete generation GO:0007292 254 0.069
negative regulation of biological process GO:0048519 567 0.069
organelle fission GO:0048285 363 0.069
vulval development GO:0040025 333 0.068
regulation of cell division GO:0051302 142 0.068
regulation of gene expression GO:0010468 366 0.068
cell fate commitment GO:0045165 139 0.068
death GO:0016265 547 0.066
protein metabolic process GO:0019538 422 0.065
cellular component biogenesis GO:0044085 297 0.063
regulation of metabolic process GO:0019222 478 0.061
phosphorylation GO:0016310 116 0.060
regulation of cellular metabolic process GO:0031323 305 0.058
chromosome organization GO:0051276 104 0.058
cellular biosynthetic process GO:0044249 315 0.058
gonad development GO:0008406 840 0.057
nucleic acid templated transcription GO:0097659 169 0.056
oocyte development GO:0048599 44 0.056
cellular protein modification process GO:0006464 207 0.055
defense response GO:0006952 296 0.055
Worm
positive regulation of macromolecule metabolic process GO:0010604 149 0.054
reproductive structure development GO:0048608 850 0.054
post embryonic organ development GO:0048569 336 0.054
nucleic acid metabolic process GO:0090304 299 0.054
negative regulation of metabolic process GO:0009892 240 0.053
single organism signaling GO:0044700 401 0.053
Worm
carbohydrate derivative metabolic process GO:1901135 141 0.053
protein modification process GO:0036211 207 0.052
organophosphate metabolic process GO:0019637 125 0.052
cellular nitrogen compound biosynthetic process GO:0044271 192 0.051
regulation of cellular component organization GO:0051128 248 0.051
regulation of transcription dna templated GO:0006355 164 0.049
cell death GO:0008219 547 0.048
cellular component assembly GO:0022607 293 0.048
macromolecular complex assembly GO:0065003 193 0.047
cellular macromolecular complex assembly GO:0034622 184 0.047
ribonucleoside catabolic process GO:0042454 77 0.046
organonitrogen compound metabolic process GO:1901564 151 0.046
cytoskeleton organization GO:0007010 339 0.045
multicellular organism growth GO:0035264 385 0.045
muscle cell differentiation GO:0042692 171 0.044
establishment of localization in cell GO:0051649 318 0.044
negative regulation of cellular process GO:0048523 239 0.043
oogenesis GO:0048477 229 0.043
regulation of developmental growth GO:0048638 389 0.041
meiotic nuclear division GO:0007126 300 0.041
developmental growth GO:0048589 412 0.041
microtubule based process GO:0007017 182 0.041
growth GO:0040007 562 0.041
regulation of signaling GO:0023051 172 0.041
regulation of growth GO:0040008 409 0.041
epithelial cell proliferation GO:0050673 1 0.040
gene expression GO:0010467 412 0.040
organelle assembly GO:0070925 214 0.040
cellular macromolecule localization GO:0070727 75 0.039
meiotic chromosome segregation GO:0045132 139 0.039
meiotic cell cycle process GO:1903046 170 0.039
regulation of cell cycle process GO:0010564 145 0.039
aging GO:0007568 812 0.038
phosphate containing compound metabolic process GO:0006796 232 0.038
purine ribonucleotide metabolic process GO:0009150 95 0.037
transport GO:0006810 1093 0.036
purine ribonucleoside metabolic process GO:0046128 92 0.036
positive regulation of multicellular organismal process GO:0051240 417 0.034
regulation of rna biosynthetic process GO:2001141 165 0.034
positive regulation of developmental growth GO:0048639 354 0.034
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.033
ribose phosphate metabolic process GO:0019693 99 0.033
protein localization GO:0008104 205 0.033
negative regulation of macromolecule metabolic process GO:0010605 229 0.032
regulation of locomotion GO:0040012 161 0.032
regulation of macromolecule biosynthetic process GO:0010556 189 0.032
vesicle mediated transport GO:0016192 852 0.032
ribonucleoside metabolic process GO:0009119 98 0.032
cytoskeleton dependent cytokinesis GO:0061640 35 0.032
endocytosis GO:0006897 819 0.031
neurogenesis GO:0022008 236 0.031
innate immune response GO:0045087 190 0.031
negative regulation of cellular metabolic process GO:0031324 95 0.031
regulation of cell communication GO:0010646 176 0.030
signaling GO:0023052 401 0.030
Worm
cellular protein complex assembly GO:0043623 178 0.030
cellular component morphogenesis GO:0032989 318 0.030
positive regulation of developmental process GO:0051094 408 0.030
receptor mediated endocytosis GO:0006898 715 0.030
oocyte differentiation GO:0009994 45 0.029
cell projection morphogenesis GO:0048858 148 0.029
negative regulation of nematode larval development GO:0061064 208 0.029
nucleobase containing compound metabolic process GO:0006139 406 0.029
neuron projection development GO:0031175 187 0.029
cell projection organization GO:0030030 231 0.029
taxis GO:0042330 128 0.029
rna biosynthetic process GO:0032774 169 0.028
axon development GO:0061564 163 0.028
female meiotic division GO:0007143 17 0.027
sex differentiation GO:0007548 909 0.027
cellular protein localization GO:0034613 75 0.027
regulation of vulval development GO:0040028 248 0.027
regulation of multicellular organism growth GO:0040014 373 0.027
gene silencing GO:0016458 143 0.027
biosynthetic process GO:0009058 323 0.026
cellular macromolecule biosynthetic process GO:0034645 247 0.026
positive regulation of multicellular organism growth GO:0040018 352 0.026
digestive tract development GO:0048565 122 0.026
regulation of gene expression epigenetic GO:0040029 163 0.026
organic substance biosynthetic process GO:1901576 323 0.025
phosphorus metabolic process GO:0006793 232 0.025
regulation of post embryonic development GO:0048580 260 0.025
positive regulation of growth GO:0045927 369 0.024
regulation of nitrogen compound metabolic process GO:0051171 222 0.024
regulation of primary metabolic process GO:0080090 292 0.024
nucleobase containing compound biosynthetic process GO:0034654 184 0.023
establishment of localization GO:0051234 1171 0.023
generation of neurons GO:0048699 235 0.023
oxoacid metabolic process GO:0043436 47 0.023
positive regulation of cellular metabolic process GO:0031325 178 0.023
glycosyl compound metabolic process GO:1901657 100 0.022
nucleobase containing small molecule metabolic process GO:0055086 115 0.022
enzyme linked receptor protein signaling pathway GO:0007167 50 0.022
regulation of apoptotic signaling pathway GO:2001233 1 0.022
signal transduction GO:0007165 317 0.022
Worm
aromatic compound catabolic process GO:0019439 116 0.021
striated muscle cell differentiation GO:0051146 158 0.021
catabolic process GO:0009056 318 0.021
negative regulation of developmental process GO:0051093 227 0.021
small molecule metabolic process GO:0044281 186 0.021
nucleotide metabolic process GO:0009117 108 0.021
macromolecule catabolic process GO:0009057 202 0.020
positive regulation of cell projection organization GO:0031346 4 0.020
positive regulation of protein metabolic process GO:0051247 45 0.020
membrane depolarization GO:0051899 1 0.020
multicellular organismal aging GO:0010259 812 0.020
carboxylic acid metabolic process GO:0019752 34 0.019
heterocycle biosynthetic process GO:0018130 187 0.019
protein catabolic process GO:0030163 162 0.019
organic cyclic compound biosynthetic process GO:1901362 195 0.019
regulation of molecular function GO:0065009 89 0.019
cellular ketone metabolic process GO:0042180 14 0.019
programmed cell death GO:0012501 500 0.019
chemotaxis GO:0006935 120 0.019
cell proliferation GO:0008283 116 0.019
cellular component assembly involved in morphogenesis GO:0010927 183 0.018
regulation of multicellular organismal development GO:2000026 317 0.018
developmental maturation GO:0021700 26 0.018
posttranscriptional regulation of gene expression GO:0010608 166 0.018
determination of adult lifespan GO:0008340 812 0.018
digestive system development GO:0055123 122 0.018
regulation of meiotic cell cycle GO:0051445 136 0.018
protein complex biogenesis GO:0070271 186 0.018
macromolecule biosynthetic process GO:0009059 250 0.018
positive regulation of neurogenesis GO:0050769 4 0.018
purine ribonucleoside catabolic process GO:0046130 75 0.018
organonitrogen compound catabolic process GO:1901565 90 0.017
positive regulation of locomotion GO:0040017 42 0.017
cell part morphogenesis GO:0032990 152 0.017
dna metabolic process GO:0006259 74 0.017
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.017
regulation of cellular ketone metabolic process GO:0010565 3 0.017
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.017
organic acid metabolic process GO:0006082 47 0.017
cellular amine metabolic process GO:0044106 15 0.017
cellular catabolic process GO:0044248 199 0.017
homeostatic process GO:0042592 51 0.017
organic cyclic compound catabolic process GO:1901361 119 0.017
regulation of epithelial cell proliferation GO:0050678 1 0.016
negative regulation of gene expression GO:0010629 217 0.016
transcription dna templated GO:0006351 168 0.016
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.016
inductive cell migration GO:0040039 145 0.016
response to wounding GO:0009611 4 0.016
spindle organization GO:0007051 92 0.016
single organism localization GO:1902578 518 0.016
cell maturation GO:0048469 26 0.016
regulation of response to stimulus GO:0048583 243 0.016
cellular response to dna damage stimulus GO:0006974 41 0.016
positive regulation of cellular component organization GO:0051130 34 0.015
internal peptidyl lysine acetylation GO:0018393 3 0.015
regulation of cellular biosynthetic process GO:0031326 189 0.015
axon guidance GO:0007411 82 0.015
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.015
organophosphate catabolic process GO:0046434 81 0.015
positive regulation of cell communication GO:0010647 69 0.015
ribonucleotide metabolic process GO:0009259 99 0.015
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.015
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.015
purine containing compound catabolic process GO:0072523 75 0.015
apoptotic process GO:0006915 478 0.015
organic substance catabolic process GO:1901575 294 0.015
regulation of cellular amino acid metabolic process GO:0006521 0 0.015
regulation of cell proliferation GO:0042127 105 0.014
system process GO:0003008 136 0.014
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.014
cell morphogenesis involved in differentiation GO:0000904 112 0.014
negative regulation of rna metabolic process GO:0051253 53 0.014
regulation of biosynthetic process GO:0009889 189 0.014
actin cytoskeleton organization GO:0030036 184 0.014
negative regulation of cellular biosynthetic process GO:0031327 65 0.014
actin filament based process GO:0030029 191 0.013
chromosome organization involved in meiosis GO:0070192 25 0.013
amine metabolic process GO:0009308 15 0.013
meiotic cytokinesis GO:0033206 15 0.013
protein oligomerization GO:0051259 4 0.013
nucleoside metabolic process GO:0009116 99 0.013
cellular amino acid metabolic process GO:0006520 15 0.013
regulation of cell cycle GO:0051726 194 0.013
single organism cellular localization GO:1902580 72 0.013
negative regulation of multicellular organismal process GO:0051241 236 0.013
calcium mediated signaling GO:0019722 3 0.013
mitotic spindle organization GO:0007052 81 0.013
regulation of cellular amine metabolic process GO:0033238 0 0.013
protein phosphorylation GO:0006468 85 0.013
ribonucleoside triphosphate catabolic process GO:0009203 72 0.013
chromosome segregation GO:0007059 180 0.013
mitotic spindle stabilization GO:0043148 2 0.013
purine nucleoside triphosphate metabolic process GO:0009144 87 0.012
response to external stimulus GO:0009605 289 0.012
Worm
positive regulation of chromosome organization GO:2001252 2 0.012
cellular response to stress GO:0033554 162 0.012
Worm
regulation of anatomical structure morphogenesis GO:0022603 51 0.012
myofibril assembly GO:0030239 154 0.012
negative regulation of post embryonic development GO:0048581 208 0.012
spermatogenesis GO:0007283 41 0.012
regulation of cellular component movement GO:0051270 62 0.012
protein complex assembly GO:0006461 186 0.012
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.012
muscle tissue development GO:0060537 1 0.012
response to organic substance GO:0010033 131 0.012
Worm
regulation of cellular component biogenesis GO:0044087 26 0.012
establishment of cell polarity GO:0030010 46 0.012
positive regulation of metabolic process GO:0009893 187 0.012
response to heat GO:0009408 50 0.012
Worm
chromatin assembly or disassembly GO:0006333 1 0.012
rna metabolic process GO:0016070 228 0.012
regulation of nuclear division GO:0051783 115 0.012
nucleoside phosphate metabolic process GO:0006753 108 0.012
covalent chromatin modification GO:0016569 30 0.012
muscle structure development GO:0061061 191 0.011
neuromuscular junction development GO:0007528 2 0.011
glycosyl compound catabolic process GO:1901658 79 0.011
transcription from rna polymerase ii promoter GO:0006366 149 0.011
guanosine containing compound catabolic process GO:1901069 48 0.011
male gamete generation GO:0048232 41 0.011
actomyosin structure organization GO:0031032 154 0.010
nucleobase containing compound catabolic process GO:0034655 114 0.010
regulation of cell migration GO:0030334 55 0.010
g1 s transition of mitotic cell cycle GO:0000082 2 0.010
response to acid chemical GO:0001101 4 0.010
negative regulation of rna biosynthetic process GO:1902679 53 0.010
negative regulation of cellular protein metabolic process GO:0032269 27 0.010

sip-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.015
disease of anatomical entity DOID:7 0 0.011