Caenorhabditis elegans

51 known processes

pqn-59 (CELE_R119.4)

Protein PQN-59

pqn-59 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development GO:0009790 3052 0.953
embryo development ending in birth or egg hatching GO:0009792 2992 0.944
multicellular organism reproduction GO:0032504 819 0.900
locomotion GO:0040011 1634 0.890
protein complex subunit organization GO:0071822 280 0.790
macromolecular complex subunit organization GO:0043933 320 0.651
nucleobase containing compound biosynthetic process GO:0034654 184 0.619
meiotic chromosome segregation GO:0045132 139 0.617
cellular component assembly GO:0022607 293 0.600
gene expression GO:0010467 412 0.599
cellular component morphogenesis GO:0032989 318 0.592
organic substance biosynthetic process GO:1901576 323 0.576
macromolecule biosynthetic process GO:0009059 250 0.573
multicellular organismal reproductive process GO:0048609 815 0.570
gamete generation GO:0007276 461 0.563
cellular macromolecular complex assembly GO:0034622 184 0.562
cell cycle GO:0007049 526 0.530
regulation of macromolecule metabolic process GO:0060255 421 0.522
cellular macromolecule biosynthetic process GO:0034645 247 0.518
germ cell development GO:0007281 351 0.514
catabolic process GO:0009056 318 0.486
meiotic cell cycle GO:0051321 335 0.480
post embryonic development GO:0009791 2152 0.455
meiotic nuclear division GO:0007126 300 0.443
biosynthetic process GO:0009058 323 0.441
cellular nitrogen compound biosynthetic process GO:0044271 192 0.413
protein metabolic process GO:0019538 422 0.409
cellular protein modification process GO:0006464 207 0.402
meiotic cell cycle process GO:1903046 170 0.400
female gamete generation GO:0007292 254 0.390
body morphogenesis GO:0010171 620 0.390
nucleic acid metabolic process GO:0090304 299 0.388
genitalia development GO:0048806 741 0.388
regulation of rna biosynthetic process GO:2001141 165 0.384
aromatic compound biosynthetic process GO:0019438 192 0.368
nucleic acid templated transcription GO:0097659 169 0.367
developmental process involved in reproduction GO:0003006 1165 0.363
protein modification process GO:0036211 207 0.363
positive regulation of transcription dna templated GO:0045893 102 0.361
organelle organization GO:0006996 783 0.357
single organism reproductive process GO:0044702 1196 0.355
Human
regulation of cellular metabolic process GO:0031323 305 0.343
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.323
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.313
cellular protein metabolic process GO:0044267 279 0.304
multicellular organismal aging GO:0010259 812 0.297
chromosome segregation GO:0007059 180 0.290
macromolecular complex assembly GO:0065003 193 0.289
protein complex assembly GO:0006461 186 0.287
regulation of macromolecule biosynthetic process GO:0010556 189 0.287
macromolecule modification GO:0043412 218 0.282
microtubule based process GO:0007017 182 0.267
cellular component biogenesis GO:0044085 297 0.263
transcription from rna polymerase ii promoter GO:0006366 149 0.261
sexual reproduction GO:0019953 546 0.259
Human
positive regulation of gene expression GO:0010628 112 0.253
organic cyclic compound biosynthetic process GO:1901362 195 0.249
heterocycle biosynthetic process GO:0018130 187 0.247
negative regulation of biological process GO:0048519 567 0.242
regulation of nitrogen compound metabolic process GO:0051171 222 0.242
gonad development GO:0008406 840 0.239
regulation of nucleic acid templated transcription GO:1903506 165 0.238
determination of adult lifespan GO:0008340 812 0.224
multi organism reproductive process GO:0044703 867 0.223
Human
oviposition GO:0018991 364 0.223
cell death GO:0008219 547 0.218
regulation of metabolic process GO:0019222 478 0.216
regulation of cellular biosynthetic process GO:0031326 189 0.215
regulation of transcription dna templated GO:0006355 164 0.212
multicellular organismal reproductive behavior GO:0033057 384 0.205
regulation of biosynthetic process GO:0009889 189 0.195
endocytosis GO:0006897 819 0.188
phosphorus metabolic process GO:0006793 232 0.183
neurogenesis GO:0022008 236 0.178
rna metabolic process GO:0016070 228 0.175
regulation of multicellular organismal process GO:0051239 726 0.172
protein complex biogenesis GO:0070271 186 0.170
anatomical structure formation involved in morphogenesis GO:0048646 250 0.167
cellular response to organic substance GO:0071310 119 0.166
oogenesis GO:0048477 229 0.166
spermatogenesis GO:0007283 41 0.166
regulation of primary metabolic process GO:0080090 292 0.166
programmed cell death GO:0012501 500 0.164
protein import GO:0017038 9 0.158
regulation of response to stimulus GO:0048583 243 0.154
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.154
positive regulation of cellular metabolic process GO:0031325 178 0.150
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.150
generation of neurons GO:0048699 235 0.147
protein import into nucleus GO:0006606 6 0.146
response to organic substance GO:0010033 131 0.143
reproductive system development GO:0061458 850 0.141
chromosome organization GO:0051276 104 0.140
single organism signaling GO:0044700 401 0.139
organ development GO:0048513 1102 0.139
skeletal muscle organ development GO:0060538 3 0.134
cell division GO:0051301 262 0.131
aging GO:0007568 812 0.130
establishment of mitotic spindle orientation GO:0000132 28 0.130
transcription dna templated GO:0006351 168 0.129
signal transduction GO:0007165 317 0.127
positive regulation of metabolic process GO:0009893 187 0.126
positive regulation of cellular process GO:0048522 332 0.125
cell cycle process GO:0022402 482 0.120
hermaphrodite genitalia development GO:0040035 734 0.119
chromatin organization GO:0006325 32 0.117
negative regulation of cellular process GO:0048523 239 0.117
regulation of gene expression GO:0010468 366 0.114
signaling GO:0023052 401 0.113
sex differentiation GO:0007548 909 0.113
positive regulation of nucleic acid templated transcription GO:1903508 102 0.112
cellular biosynthetic process GO:0044249 315 0.111
regulation of nucleocytoplasmic transport GO:0046822 3 0.111
response to external stimulus GO:0009605 289 0.110
negative regulation of macromolecule metabolic process GO:0010605 229 0.109
mitotic cell cycle process GO:1903047 194 0.108
organelle fission GO:0048285 363 0.108
behavior GO:0007610 527 0.106
rna biosynthetic process GO:0032774 169 0.106
response to chemical GO:0042221 356 0.105
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.104
histone modification GO:0016570 30 0.102
nucleobase containing compound metabolic process GO:0006139 406 0.101
protein localization GO:0008104 205 0.100
transport GO:0006810 1093 0.096
receptor mediated endocytosis GO:0006898 715 0.096
cellular catabolic process GO:0044248 199 0.096
vesicle mediated transport GO:0016192 852 0.095
nucleus organization GO:0006997 38 0.095
establishment of localization GO:0051234 1171 0.094
macromolecule localization GO:0033036 771 0.094
oocyte differentiation GO:0009994 45 0.093
reproductive structure development GO:0048608 850 0.092
nervous system development GO:0007399 253 0.092
cellular response to stress GO:0033554 162 0.092
multi multicellular organism process GO:0044706 390 0.090
development of primary sexual characteristics GO:0045137 840 0.088
cell cycle switching mitotic to meiotic cell cycle GO:0051728 35 0.087
response to heat GO:0009408 50 0.086
regulation of cell cycle process GO:0010564 145 0.085
neuron projection development GO:0031175 187 0.085
intracellular signal transduction GO:0035556 96 0.083
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.083
chromatin modification GO:0016568 32 0.082
regulation of rna metabolic process GO:0051252 173 0.081
regulation of locomotion GO:0040012 161 0.080
regulation of protein metabolic process GO:0051246 81 0.079
lipid localization GO:0010876 573 0.078
male gamete generation GO:0048232 41 0.078
regulation of meiotic cell cycle GO:0051445 136 0.076
positive regulation of macromolecule metabolic process GO:0010604 149 0.076
reproductive behavior GO:0019098 387 0.076
protein phosphorylation GO:0006468 85 0.075
regulation of nematode larval development GO:0061062 260 0.073
defense response GO:0006952 296 0.072
cellular protein complex assembly GO:0043623 178 0.071
tissue development GO:0009888 112 0.070
maintenance of location GO:0051235 580 0.069
organelle assembly GO:0070925 214 0.069
regulation of biological quality GO:0065008 741 0.068
response to acid chemical GO:0001101 4 0.068
cell development GO:0048468 696 0.068
mitotic spindle organization GO:0007052 81 0.067
positive regulation of rna metabolic process GO:0051254 103 0.065
phosphate containing compound metabolic process GO:0006796 232 0.065
negative regulation of cellular catabolic process GO:0031330 9 0.064
lipid storage GO:0019915 565 0.063
phagocytosis GO:0006909 115 0.063
establishment of localization in cell GO:0051649 318 0.063
regulation of developmental process GO:0050793 684 0.062
multi organism reproductive behavior GO:0044705 387 0.062
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.062
molting cycle GO:0042303 281 0.062
positive regulation of biosynthetic process GO:0009891 109 0.061
positive regulation of developmental growth GO:0048639 354 0.061
multi organism behavior GO:0051705 389 0.061
regulation of organelle organization GO:0033043 164 0.060
apoptotic process GO:0006915 478 0.059
positive regulation of intracellular transport GO:0032388 2 0.059
positive regulation of growth GO:0045927 369 0.058
system process GO:0003008 136 0.057
sister chromatid segregation GO:0000819 46 0.056
regulation of cellular component organization GO:0051128 248 0.055
chromosome organization involved in meiosis GO:0070192 25 0.054
regulation of molecular function GO:0065009 89 0.054
single organism nuclear import GO:1902593 6 0.053
regulation of signaling GO:0023051 172 0.053
organic substance catabolic process GO:1901575 294 0.053
autophagy GO:0006914 29 0.052
regulation of vulval development GO:0040028 248 0.052
phosphorylation GO:0016310 116 0.051
negative regulation of rna biosynthetic process GO:1902679 53 0.050
dna templated transcription initiation GO:0006352 3 0.049
positive regulation of cellular biosynthetic process GO:0031328 109 0.049
transcription initiation from rna polymerase ii promoter GO:0006367 2 0.048
regulation of cytoplasmic transport GO:1903649 3 0.048
cell motility GO:0048870 313 0.048
regulation of growth GO:0040008 409 0.047
regulation of stem cell differentiation GO:2000736 1 0.047
positive regulation of signaling GO:0023056 66 0.046
developmental growth GO:0048589 412 0.046
negative regulation of gene expression GO:0010629 217 0.046
cellular protein localization GO:0034613 75 0.046
small molecule metabolic process GO:0044281 186 0.046
growth GO:0040007 562 0.045
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.045
positive regulation of signal transduction GO:0009967 40 0.045
protein modification by small protein conjugation or removal GO:0070647 40 0.045
positive regulation of multicellular organismal process GO:0051240 417 0.045
regulation of protein import into nucleus GO:0042306 3 0.045
multicellular organism growth GO:0035264 385 0.044
regulation of cell communication GO:0010646 176 0.043
vulval development GO:0040025 333 0.043
localization of cell GO:0051674 313 0.043
regulation of meiosis GO:0040020 94 0.043
negative regulation of metabolic process GO:0009892 240 0.042
regulation of protein localization GO:0032880 50 0.041
negative regulation of developmental process GO:0051093 227 0.041
regulation of cell cycle GO:0051726 194 0.041
intracellular transport GO:0046907 77 0.041
regulation of organ morphogenesis GO:2000027 4 0.041
negative regulation of cellular metabolic process GO:0031324 95 0.040
protein catabolic process GO:0030163 162 0.039
single organism cellular localization GO:1902580 72 0.039
axon development GO:0061564 163 0.039
muscle tissue development GO:0060537 1 0.039
negative regulation of biosynthetic process GO:0009890 65 0.039
cell migration GO:0016477 306 0.039
rna interference GO:0016246 137 0.039
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.038
cellular component movement GO:0006928 388 0.038
striated muscle cell differentiation GO:0051146 158 0.038
response to abiotic stimulus GO:0009628 152 0.038
protein dna complex subunit organization GO:0071824 7 0.038
regulation of signal transduction GO:0009966 135 0.037
regulation of developmental growth GO:0048638 389 0.037
proteolysis GO:0006508 61 0.037
regulation of cell motility GO:2000145 57 0.037
cell projection morphogenesis GO:0048858 148 0.036
negative regulation of transcription dna templated GO:0045892 53 0.036
posttranscriptional regulation of gene expression GO:0010608 166 0.036
regulation of multicellular organism growth GO:0040014 373 0.036
cell morphogenesis GO:0000902 163 0.036
internal peptidyl lysine acetylation GO:0018393 3 0.035
cellular macromolecule localization GO:0070727 75 0.035
neuron development GO:0048666 199 0.035
negative regulation of cellular biosynthetic process GO:0031327 65 0.034
neuron differentiation GO:0030182 217 0.034
single organism organelle organization GO:1902589 501 0.034
protein localization to organelle GO:0033365 37 0.034
positive regulation of rna biosynthetic process GO:1902680 102 0.033
spindle localization GO:0051653 51 0.032
positive regulation of intracellular protein transport GO:0090316 2 0.032
establishment of organelle localization GO:0051656 123 0.032
positive regulation of catalytic activity GO:0043085 59 0.032
single organism intracellular transport GO:1902582 70 0.031
response to other organism GO:0051707 101 0.031
cell projection organization GO:0030030 231 0.030
muscle structure development GO:0061061 191 0.030
regulation of multicellular organismal development GO:2000026 317 0.030
death GO:0016265 547 0.029
immune response GO:0006955 192 0.029
gene silencing GO:0016458 143 0.029
cytoplasmic transport GO:0016482 23 0.029
negative regulation of post embryonic development GO:0048581 208 0.029
cell morphogenesis involved in differentiation GO:0000904 112 0.028
covalent chromatin modification GO:0016569 30 0.028
negative regulation of vulval development GO:0040027 206 0.028
single organism transport GO:0044765 447 0.028
macromolecule catabolic process GO:0009057 202 0.028
protein targeting GO:0006605 10 0.028
regulation of cell division GO:0051302 142 0.028
regulation of cellular protein metabolic process GO:0032268 75 0.028
organic substance transport GO:0071702 113 0.027
spindle organization GO:0007051 92 0.027
post embryonic organ development GO:0048569 336 0.027
positive regulation of protein transport GO:0051222 4 0.027
regulation of protein localization to nucleus GO:1900180 5 0.027
single organism localization GO:1902578 518 0.027
positive regulation of cell cycle GO:0045787 55 0.026
head development GO:0060322 1 0.026
cell part morphogenesis GO:0032990 152 0.026
fertilization GO:0009566 63 0.026
Human
response to external biotic stimulus GO:0043207 101 0.025
positive regulation of protein metabolic process GO:0051247 45 0.025
regulation of protein targeting GO:1903533 3 0.025
myosin filament organization GO:0031033 138 0.025
dna metabolic process GO:0006259 74 0.024
collagen and cuticulin based cuticle development GO:0040002 99 0.024
negative regulation of nucleic acid templated transcription GO:1903507 53 0.024
regulation of intracellular signal transduction GO:1902531 77 0.024
regulation of cell migration GO:0030334 55 0.023
actomyosin structure organization GO:0031032 154 0.023
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.023
response to nutrient levels GO:0031667 35 0.023
organelle localization GO:0051640 127 0.023
negative regulation of rna metabolic process GO:0051253 53 0.023
striated muscle myosin thick filament assembly GO:0071688 138 0.023
axonal fasciculation GO:0007413 79 0.023
muscle cell differentiation GO:0042692 171 0.023
single organism behavior GO:0044708 83 0.023
single organism biosynthetic process GO:0044711 91 0.023
regulation of apoptotic signaling pathway GO:2001233 1 0.023
regulation of canonical wnt signaling pathway GO:0060828 1 0.022
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.022
positive regulation of cellular component organization GO:0051130 34 0.022
protein modification by small protein conjugation GO:0032446 31 0.022
regulation of cellular component movement GO:0051270 62 0.022
mitotic nuclear division GO:0007067 89 0.022
axonogenesis GO:0007409 102 0.022
neuron projection morphogenesis GO:0048812 114 0.022
actin cytoskeleton organization GO:0030036 184 0.022
positive regulation of multicellular organism growth GO:0040018 352 0.022
positive regulation of protein complex assembly GO:0031334 6 0.021
cytoskeleton organization GO:0007010 339 0.021
protein dna complex assembly GO:0065004 7 0.021
response to topologically incorrect protein GO:0035966 82 0.021
oocyte development GO:0048599 44 0.021
regulation of phosphate metabolic process GO:0019220 81 0.021
regulation of protein stability GO:0031647 3 0.021
regulation of post embryonic development GO:0048580 260 0.021
modification dependent protein catabolic process GO:0019941 32 0.021
regulation of localization GO:0032879 194 0.021
muscle cell development GO:0055001 158 0.020
positive regulation of cell migration GO:0030335 3 0.020
organic cyclic compound catabolic process GO:1901361 119 0.020
gene silencing by rna GO:0031047 143 0.020
negative regulation of multicellular organismal process GO:0051241 236 0.020
regulation of protein complex assembly GO:0043254 12 0.020
cuticle development GO:0042335 100 0.020
striated muscle cell development GO:0055002 157 0.020
establishment of cell polarity GO:0030010 46 0.020
regulation of cellular catabolic process GO:0031329 51 0.020
protein localization to nucleus GO:0034504 11 0.020
cellular response to chemical stimulus GO:0070887 129 0.019
myofibril assembly GO:0030239 154 0.019
regulation of catalytic activity GO:0050790 78 0.019
cellular response to abiotic stimulus GO:0071214 4 0.019
transcription elongation from rna polymerase ii promoter GO:0006368 1 0.019
glycosyl compound metabolic process GO:1901657 100 0.019
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.019
canonical wnt signaling pathway GO:0060070 3 0.019
heterocycle catabolic process GO:0046700 119 0.018
positive regulation of meiotic cell cycle GO:0051446 47 0.018
translational initiation GO:0006413 2 0.018
positive regulation of molecular function GO:0044093 61 0.018
development of primary male sexual characteristics GO:0046546 4 0.018
regulation of transport GO:0051049 91 0.018
dauer larval development GO:0040024 92 0.018
regulation of gene expression epigenetic GO:0040029 163 0.017
peptidyl amino acid modification GO:0018193 58 0.017
cell surface receptor signaling pathway GO:0007166 149 0.017
single fertilization GO:0007338 61 0.017
Human
positive regulation of cell death GO:0010942 38 0.017
nucleobase containing compound catabolic process GO:0034655 114 0.016
internal protein amino acid acetylation GO:0006475 3 0.016
male sex differentiation GO:0046661 86 0.016
actomyosin contractile ring organization GO:0044837 1 0.016
cellular localization GO:0051641 360 0.016
response to amino acid GO:0043200 1 0.016
aromatic compound catabolic process GO:0019439 116 0.016
negative regulation of signaling GO:0023057 61 0.016
positive regulation of catabolic process GO:0009896 38 0.016
muscle organ development GO:0007517 26 0.015
cellular component assembly involved in morphogenesis GO:0010927 183 0.015
actin filament based process GO:0030029 191 0.015
peptidyl lysine acetylation GO:0018394 3 0.015
negative regulation of mitotic cell cycle GO:0045930 42 0.015
cell cycle g1 s phase transition GO:0044843 2 0.015
response to endoplasmic reticulum stress GO:0034976 71 0.015
microtubule polymerization or depolymerization GO:0031109 22 0.015
establishment of spindle localization GO:0051293 51 0.015
posttranscriptional gene silencing by rna GO:0035194 143 0.015
proteasomal protein catabolic process GO:0010498 20 0.015
neurological system process GO:0050877 53 0.015
response to unfolded protein GO:0006986 71 0.015
nuclear import GO:0051170 8 0.015
rna catabolic process GO:0006401 21 0.014
cytokinesis GO:0000910 80 0.014
regulation of chromosome organization GO:0033044 20 0.014
positive regulation of developmental process GO:0051094 408 0.014
negative regulation of nematode larval development GO:0061064 208 0.014
nucleobase containing small molecule metabolic process GO:0055086 115 0.014
protein oligomerization GO:0051259 4 0.014
defense response to other organism GO:0098542 100 0.014
posttranscriptional gene silencing GO:0016441 143 0.014
positive regulation of phosphate metabolic process GO:0045937 56 0.014
olfactory behavior GO:0042048 27 0.014
positive regulation of chromosome organization GO:2001252 2 0.014
positive regulation of response to stimulus GO:0048584 55 0.014
protein targeting to nucleus GO:0044744 6 0.014
regulation of nuclear division GO:0051783 115 0.014
ribonucleoprotein complex assembly GO:0022618 4 0.014
female meiotic division GO:0007143 17 0.014
taxis GO:0042330 128 0.014
negative regulation of cell cycle GO:0045786 53 0.013
protein transport GO:0015031 45 0.013
positive regulation of cell communication GO:0010647 69 0.013
axon guidance GO:0007411 82 0.013
regulation of phosphorus metabolic process GO:0051174 81 0.013
learning or memory GO:0007611 27 0.013
tube development GO:0035295 126 0.013
intracellular receptor signaling pathway GO:0030522 2 0.013
establishment of protein localization GO:0045184 50 0.013
mitotic sister chromatid segregation GO:0000070 38 0.013
myosin filament assembly GO:0031034 138 0.013
germline cell cycle switching mitotic to meiotic cell cycle GO:0051729 35 0.013
regulation of cellular carbohydrate metabolic process GO:0010675 2 0.013
amine metabolic process GO:0009308 15 0.012
cellular amine metabolic process GO:0044106 15 0.012
positive regulation of mitotic sister chromatid separation GO:1901970 1 0.012
modification dependent macromolecule catabolic process GO:0043632 32 0.012
positive regulation of transport GO:0051050 32 0.012
regulation of atp catabolic process GO:1903289 3 0.012
g1 s transition of mitotic cell cycle GO:0000082 2 0.012
macromolecular complex disassembly GO:0032984 20 0.012
chromatin assembly or disassembly GO:0006333 1 0.012
chromatin remodeling GO:0006338 2 0.011
regulation of cellular ketone metabolic process GO:0010565 3 0.011
apical junction assembly GO:0043297 1 0.011
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.011
small gtpase mediated signal transduction GO:0007264 32 0.011
cellular response to unfolded protein GO:0034620 71 0.011
positive regulation of organ growth GO:0046622 4 0.011
neuron recognition GO:0008038 83 0.011
response to biotic stimulus GO:0009607 101 0.011
oxoacid metabolic process GO:0043436 47 0.011
positive regulation of cellular component biogenesis GO:0044089 9 0.011
cellular macromolecule catabolic process GO:0044265 73 0.011
endoplasmic reticulum unfolded protein response GO:0030968 66 0.011
establishment of spindle orientation GO:0051294 34 0.011
response to temperature stimulus GO:0009266 66 0.011
positive regulation of protein localization to nucleus GO:1900182 2 0.011
organonitrogen compound metabolic process GO:1901564 151 0.011
regulation of cellular amino acid metabolic process GO:0006521 0 0.011
pre mirna processing GO:0031054 3 0.011
regulation of phosphorylation GO:0042325 45 0.010
chromatin assembly GO:0031497 1 0.010
ribonucleotide catabolic process GO:0009261 75 0.010
positive regulation of ras protein signal transduction GO:0046579 7 0.010
asymmetric protein localization GO:0008105 35 0.010

pqn-59 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.035
nervous system disease DOID:863 0 0.023