Caenorhabditis elegans

121 known processes

pie-1 (CELE_Y49E10.14)

Protein PIE-1

pie-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development ending in birth or egg hatching GO:0009792 2992 0.622
post embryonic development GO:0009791 2152 0.555
cell cycle process GO:0022402 482 0.463
developmental process involved in reproduction GO:0003006 1165 0.386
macromolecule biosynthetic process GO:0009059 250 0.365
organelle organization GO:0006996 783 0.324
embryo development GO:0009790 3052 0.320
meiotic chromosome segregation GO:0045132 139 0.319
meiotic cell cycle GO:0051321 335 0.314
regulation of nematode larval development GO:0061062 260 0.300
cell death GO:0008219 547 0.281
meiotic nuclear division GO:0007126 300 0.275
cell cycle GO:0007049 526 0.265
rna metabolic process GO:0016070 228 0.262
death GO:0016265 547 0.252
organelle fission GO:0048285 363 0.251
regulation of vulval development GO:0040028 248 0.249
regulation of macromolecule metabolic process GO:0060255 421 0.229
meiotic cell cycle process GO:1903046 170 0.227
gonad development GO:0008406 840 0.217
establishment of localization GO:0051234 1171 0.197
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.195
multi organism reproductive process GO:0044703 867 0.192
multicellular organismal reproductive process GO:0048609 815 0.182
regulation of gene expression GO:0010468 366 0.180
organic substance biosynthetic process GO:1901576 323 0.180
reproductive system development GO:0061458 850 0.178
oviposition GO:0018991 364 0.169
response to chemical GO:0042221 356 0.166
sex differentiation GO:0007548 909 0.165
chromosome segregation GO:0007059 180 0.157
apoptotic process GO:0006915 478 0.157
gene expression GO:0010467 412 0.155
establishment of organelle localization GO:0051656 123 0.154
negative regulation of biological process GO:0048519 567 0.150
regulation of cell cycle GO:0051726 194 0.146
cellular biosynthetic process GO:0044249 315 0.145
genitalia development GO:0048806 741 0.140
regulation of mitotic cell cycle GO:0007346 76 0.135
cell fate commitment GO:0045165 139 0.134
development of primary sexual characteristics GO:0045137 840 0.134
locomotion GO:0040011 1634 0.129
regulation of cell division GO:0051302 142 0.126
post embryonic organ development GO:0048569 336 0.123
multicellular organism reproduction GO:0032504 819 0.122
organ development GO:0048513 1102 0.120
negative regulation of macromolecule metabolic process GO:0010605 229 0.117
cellular protein metabolic process GO:0044267 279 0.113
negative regulation of gene expression GO:0010629 217 0.103
regulation of developmental process GO:0050793 684 0.099
regulation of multicellular organismal development GO:2000026 317 0.098
single organism reproductive process GO:0044702 1196 0.097
negative regulation of metabolic process GO:0009892 240 0.096
negative regulation of vulval development GO:0040027 206 0.094
single organism signaling GO:0044700 401 0.093
regulation of post embryonic development GO:0048580 260 0.090
biosynthetic process GO:0009058 323 0.089
determination of adult lifespan GO:0008340 812 0.089
reproductive structure development GO:0048608 850 0.087
female meiotic division GO:0007143 17 0.087
sexual reproduction GO:0019953 546 0.086
aging GO:0007568 812 0.081
regulation of metabolic process GO:0019222 478 0.078
fertilization GO:0009566 63 0.076
regulation of multicellular organismal process GO:0051239 726 0.075
regulation of macromolecule biosynthetic process GO:0010556 189 0.073
regulation of meiotic cell cycle GO:0051445 136 0.073
regulation of cell cycle process GO:0010564 145 0.073
negative regulation of developmental process GO:0051093 227 0.072
cell division GO:0051301 262 0.072
gamete generation GO:0007276 461 0.072
body morphogenesis GO:0010171 620 0.072
negative regulation of post embryonic development GO:0048581 208 0.070
negative regulation of nematode larval development GO:0061064 208 0.070
cell development GO:0048468 696 0.069
behavior GO:0007610 527 0.067
multicellular organismal aging GO:0010259 812 0.067
chromosome organization GO:0051276 104 0.066
reproductive behavior GO:0019098 387 0.066
gene silencing GO:0016458 143 0.066
regulation of rna biosynthetic process GO:2001141 165 0.065
cellular localization GO:0051641 360 0.064
hermaphrodite genitalia development GO:0040035 734 0.063
regulation of biological quality GO:0065008 741 0.063
regulation of response to stimulus GO:0048583 243 0.063
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.062
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.062
axon development GO:0061564 163 0.060
programmed cell death GO:0012501 500 0.060
multi organism reproductive behavior GO:0044705 387 0.059
receptor mediated endocytosis GO:0006898 715 0.059
single fertilization GO:0007338 61 0.058
protein metabolic process GO:0019538 422 0.058
signal transduction GO:0007165 317 0.057
maintenance of location GO:0051235 580 0.057
multicellular organismal reproductive behavior GO:0033057 384 0.056
negative regulation of cellular process GO:0048523 239 0.056
phosphorus metabolic process GO:0006793 232 0.055
single organism organelle organization GO:1902589 501 0.054
positive regulation of biosynthetic process GO:0009891 109 0.053
nucleic acid metabolic process GO:0090304 299 0.051
macromolecule localization GO:0033036 771 0.051
organelle localization GO:0051640 127 0.051
homeostatic process GO:0042592 51 0.051
lipid localization GO:0010876 573 0.050
multi organism behavior GO:0051705 389 0.050
small gtpase mediated signal transduction GO:0007264 32 0.050
growth GO:0040007 562 0.049
regulation of locomotion GO:0040012 161 0.049
endocytosis GO:0006897 819 0.049
germ cell development GO:0007281 351 0.049
vulval development GO:0040025 333 0.048
cellular macromolecule biosynthetic process GO:0034645 247 0.048
positive regulation of multicellular organismal process GO:0051240 417 0.046
transport GO:0006810 1093 0.046
lipid storage GO:0019915 565 0.046
small molecule metabolic process GO:0044281 186 0.044
positive regulation of cellular biosynthetic process GO:0031328 109 0.044
cell surface receptor signaling pathway GO:0007166 149 0.043
regulation of cellular metabolic process GO:0031323 305 0.042
posttranscriptional regulation of gene expression GO:0010608 166 0.041
multi multicellular organism process GO:0044706 390 0.041
single organism behavior GO:0044708 83 0.041
posttranscriptional gene silencing by rna GO:0035194 143 0.040
signaling GO:0023052 401 0.040
nucleoside triphosphate catabolic process GO:0009143 72 0.039
regulation of primary metabolic process GO:0080090 292 0.038
transcription dna templated GO:0006351 168 0.037
female gamete generation GO:0007292 254 0.037
regulation of meiosis GO:0040020 94 0.036
positive regulation of cellular process GO:0048522 332 0.036
regulation of nucleic acid templated transcription GO:1903506 165 0.036
regulation of cell communication GO:0010646 176 0.036
protein modification process GO:0036211 207 0.035
dauer larval development GO:0040024 92 0.035
heterocycle biosynthetic process GO:0018130 187 0.034
cellular nitrogen compound biosynthetic process GO:0044271 192 0.034
nucleic acid templated transcription GO:0097659 169 0.033
spermatogenesis GO:0007283 41 0.033
neuron development GO:0048666 199 0.033
digestive system development GO:0055123 122 0.033
protein complex biogenesis GO:0070271 186 0.033
cell proliferation GO:0008283 116 0.032
nucleobase containing compound biosynthetic process GO:0034654 184 0.032
positive regulation of macromolecule metabolic process GO:0010604 149 0.031
protein complex assembly GO:0006461 186 0.031
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.031
regulation of growth GO:0040008 409 0.030
positive regulation of rna biosynthetic process GO:1902680 102 0.030
oogenesis GO:0048477 229 0.030
response to external stimulus GO:0009605 289 0.030
regulation of apoptotic signaling pathway GO:2001233 1 0.030
pronuclear migration GO:0035046 51 0.030
multicellular organism growth GO:0035264 385 0.029
molting cycle GO:0042303 281 0.029
regulation of rna metabolic process GO:0051252 173 0.029
regulation of cellular component organization GO:0051128 248 0.029
negative regulation of mitotic cell cycle GO:0045930 42 0.029
localization of cell GO:0051674 313 0.028
regulation of multicellular organism growth GO:0040014 373 0.028
regulation of signal transduction GO:0009966 135 0.028
regulation of cell proliferation GO:0042127 105 0.028
regulation of transcription dna templated GO:0006355 164 0.028
catabolic process GO:0009056 318 0.028
negative regulation of multicellular organismal process GO:0051241 236 0.028
tube development GO:0035295 126 0.027
chromatin remodeling GO:0006338 2 0.027
cellular macromolecular complex assembly GO:0034622 184 0.026
positive regulation of multicellular organism growth GO:0040018 352 0.026
positive regulation of developmental growth GO:0048639 354 0.025
ribonucleoside catabolic process GO:0042454 77 0.025
vesicle mediated transport GO:0016192 852 0.025
taxis GO:0042330 128 0.024
positive regulation of vulval development GO:0040026 52 0.024
sex determination GO:0007530 60 0.024
positive regulation of transcription dna templated GO:0045893 102 0.024
axon guidance GO:0007411 82 0.024
protein localization GO:0008104 205 0.024
gastrulation GO:0007369 58 0.024
neuron projection development GO:0031175 187 0.023
neurogenesis GO:0022008 236 0.023
gene silencing by rna GO:0031047 143 0.023
positive regulation of developmental process GO:0051094 408 0.023
posttranscriptional gene silencing GO:0016441 143 0.023
intracellular signal transduction GO:0035556 96 0.023
organonitrogen compound metabolic process GO:1901564 151 0.023
macromolecule catabolic process GO:0009057 202 0.023
organic acid metabolic process GO:0006082 47 0.023
rna interference GO:0016246 137 0.022
microtubule based process GO:0007017 182 0.022
organelle assembly GO:0070925 214 0.022
organic substance catabolic process GO:1901575 294 0.022
positive regulation of growth GO:0045927 369 0.022
macromolecular complex subunit organization GO:0043933 320 0.022
cellular component biogenesis GO:0044085 297 0.022
mitotic cell cycle process GO:1903047 194 0.022
organism emergence from protective structure GO:0071684 48 0.022
positive regulation of cell communication GO:0010647 69 0.022
ras protein signal transduction GO:0007265 31 0.021
deoxyribonucleotide biosynthetic process GO:0009263 1 0.021
regulation of developmental growth GO:0048638 389 0.020
protein oligomerization GO:0051259 4 0.020
negative regulation of cell cycle GO:0045786 53 0.020
regulation of cell death GO:0010941 65 0.020
hatching GO:0035188 48 0.020
regulation of signaling GO:0023051 172 0.020
mitotic spindle organization GO:0007052 81 0.020
cellular protein complex assembly GO:0043623 178 0.019
cellular response to abiotic stimulus GO:0071214 4 0.019
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.019
phosphate containing compound metabolic process GO:0006796 232 0.019
developmental growth GO:0048589 412 0.019
single organism biosynthetic process GO:0044711 91 0.019
anatomical structure formation involved in morphogenesis GO:0048646 250 0.019
positive regulation of cellular metabolic process GO:0031325 178 0.019
negative regulation of cellular metabolic process GO:0031324 95 0.018
purine nucleoside triphosphate catabolic process GO:0009146 72 0.018
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.018
rna biosynthetic process GO:0032774 169 0.018
digestive tract development GO:0048565 122 0.018
dna metabolic process GO:0006259 74 0.018
cellular macromolecule catabolic process GO:0044265 73 0.018
muscle cell differentiation GO:0042692 171 0.017
phagocytosis engulfment GO:0006911 98 0.017
cellular ketone metabolic process GO:0042180 14 0.017
engulfment of apoptotic cell GO:0043652 94 0.017
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.017
nucleoside catabolic process GO:0009164 78 0.017
regulation of cellular ketone metabolic process GO:0010565 3 0.017
transcription from rna polymerase ii promoter GO:0006366 149 0.017
axonal fasciculation GO:0007413 79 0.017
neuron recognition GO:0008038 83 0.017
regulation of organelle organization GO:0033043 164 0.017
spindle localization GO:0051653 51 0.017
regulation of gene expression epigenetic GO:0040029 163 0.016
chemosensory behavior GO:0007635 33 0.016
cellular component assembly GO:0022607 293 0.016
cellular catabolic process GO:0044248 199 0.016
regulation of intracellular signal transduction GO:1902531 77 0.016
cellular response to stress GO:0033554 162 0.016
regulation of biosynthetic process GO:0009889 189 0.016
generation of neurons GO:0048699 235 0.016
head development GO:0060322 1 0.016
positive regulation of gene expression GO:0010628 112 0.016
hermaphrodite germ line sex determination GO:0040021 48 0.016
aromatic compound catabolic process GO:0019439 116 0.016
cell cycle switching mitotic to meiotic cell cycle GO:0051728 35 0.016
regulation of epithelial cell proliferation GO:0050678 1 0.015
system process GO:0003008 136 0.015
nucleoside triphosphate metabolic process GO:0009141 87 0.015
heterocycle catabolic process GO:0046700 119 0.015
aromatic compound biosynthetic process GO:0019438 192 0.015
establishment of spindle localization GO:0051293 51 0.015
mitotic nuclear division GO:0007067 89 0.015
mitotic metaphase plate congression GO:0007080 5 0.015
apoptotic cell clearance GO:0043277 111 0.015
inductive cell migration GO:0040039 145 0.015
cellular response to chemical stimulus GO:0070887 129 0.015
carboxylic acid metabolic process GO:0019752 34 0.015
regulation of nuclear division GO:0051783 115 0.015
positive regulation of rna metabolic process GO:0051254 103 0.014
macromolecule modification GO:0043412 218 0.014
cell recognition GO:0008037 85 0.014
organic cyclic compound biosynthetic process GO:1901362 195 0.014
nervous system development GO:0007399 253 0.014
cell type specific apoptotic process GO:0097285 4 0.014
establishment of nucleus localization GO:0040023 55 0.014
negative regulation of cellular protein metabolic process GO:0032269 27 0.014
peptidyl amino acid modification GO:0018193 58 0.014
single organism catabolic process GO:0044712 129 0.013
germ line sex determination GO:0018992 51 0.013
regulation of small gtpase mediated signal transduction GO:0051056 41 0.013
carbohydrate derivative catabolic process GO:1901136 82 0.013
membrane invagination GO:0010324 98 0.013
negative regulation of transcription dna templated GO:0045892 53 0.013
oxoacid metabolic process GO:0043436 47 0.013
developmental cell growth GO:0048588 39 0.013
negative regulation of rna biosynthetic process GO:1902679 53 0.013
cell migration GO:0016477 306 0.013
regulation of ras protein signal transduction GO:0046578 41 0.013
negative regulation of cellular biosynthetic process GO:0031327 65 0.013
feminization of hermaphroditic germ line GO:0040022 34 0.013
regulation of cellular component movement GO:0051270 62 0.013
nucleobase containing compound metabolic process GO:0006139 406 0.012
organic cyclic compound catabolic process GO:1901361 119 0.012
centromere complex assembly GO:0034508 5 0.012
nucleotide metabolic process GO:0009117 108 0.012
cytoskeleton organization GO:0007010 339 0.012
regulation of cellular amine metabolic process GO:0033238 0 0.012
defense response GO:0006952 296 0.012
nucleobase containing compound catabolic process GO:0034655 114 0.012
regulation of cellular biosynthetic process GO:0031326 189 0.012
pharynx development GO:0060465 51 0.012
cytokinesis GO:0000910 80 0.012
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.012
regulation of apoptotic process GO:0042981 36 0.012
digestive tract morphogenesis GO:0048546 76 0.012
nucleus localization GO:0051647 55 0.012
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.011
chemotaxis GO:0006935 120 0.011
neurological system process GO:0050877 53 0.011
male gamete generation GO:0048232 41 0.011
positive regulation of nucleic acid templated transcription GO:1903508 102 0.011
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.011
response to organic substance GO:0010033 131 0.011
cellular amine metabolic process GO:0044106 15 0.011
positive regulation of signaling GO:0023056 66 0.011
cell volume homeostasis GO:0006884 1 0.011
cellular nitrogen compound catabolic process GO:0044270 119 0.011
neuron differentiation GO:0030182 217 0.011
carbohydrate derivative metabolic process GO:1901135 141 0.011
single organism localization GO:1902578 518 0.011
translation GO:0006412 37 0.011
negative regulation of nucleic acid templated transcription GO:1903507 53 0.010
negative regulation of biosynthetic process GO:0009890 65 0.010
cellular response to topologically incorrect protein GO:0035967 76 0.010
oocyte development GO:0048599 44 0.010
developmental growth involved in morphogenesis GO:0060560 37 0.010
learning or memory GO:0007611 27 0.010
response to abiotic stimulus GO:0009628 152 0.010
cellular response to dna damage stimulus GO:0006974 41 0.010

pie-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org