Caenorhabditis elegans

64 known processes

ptr-2 (CELE_C32E8.8)

Protein PTR-2

ptr-2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development GO:0009790 3052 0.952
embryo development ending in birth or egg hatching GO:0009792 2992 0.833
cell motility GO:0048870 313 0.722
post embryonic development GO:0009791 2152 0.526
transcription dna templated GO:0006351 168 0.468
Worm
multicellular organism reproduction GO:0032504 819 0.401
positive regulation of transcription dna templated GO:0045893 102 0.399
cellular component movement GO:0006928 388 0.386
localization of cell GO:0051674 313 0.370
cell migration GO:0016477 306 0.356
transcription from rna polymerase ii promoter GO:0006366 149 0.343
Worm
development of primary sexual characteristics GO:0045137 840 0.320
positive regulation of cellular process GO:0048522 332 0.279
cell development GO:0048468 696 0.270
hermaphrodite genitalia development GO:0040035 734 0.269
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.265
receptor mediated endocytosis GO:0006898 715 0.263
establishment of localization GO:0051234 1171 0.261
Worm
positive regulation of rna biosynthetic process GO:1902680 102 0.252
cellular biosynthetic process GO:0044249 315 0.247
Worm
organ development GO:0048513 1102 0.245
Worm
determination of adult lifespan GO:0008340 812 0.238
Worm
heterocycle biosynthetic process GO:0018130 187 0.238
Worm
developmental process involved in reproduction GO:0003006 1165 0.237
regulation of metabolic process GO:0019222 478 0.236
Worm
cellular protein modification process GO:0006464 207 0.233
aromatic compound biosynthetic process GO:0019438 192 0.226
Worm
vesicle mediated transport GO:0016192 852 0.223
Worm
phosphorus metabolic process GO:0006793 232 0.220
gonad development GO:0008406 840 0.218
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.207
tissue development GO:0009888 112 0.202
protein modification process GO:0036211 207 0.196
endocytosis GO:0006897 819 0.182
Worm
nucleic acid templated transcription GO:0097659 169 0.179
Worm
organic cyclic compound biosynthetic process GO:1901362 195 0.175
Worm
germ cell development GO:0007281 351 0.171
regulation of gene expression GO:0010468 366 0.169
Worm
cell projection organization GO:0030030 231 0.168
positive regulation of metabolic process GO:0009893 187 0.165
regulation of nucleic acid templated transcription GO:1903506 165 0.162
Worm
nucleobase containing compound metabolic process GO:0006139 406 0.157
Worm
aging GO:0007568 812 0.152
Worm
genitalia development GO:0048806 741 0.151
neuron development GO:0048666 199 0.147
single organism transport GO:0044765 447 0.146
Worm
neuron projection development GO:0031175 187 0.141
regulation of cell cycle GO:0051726 194 0.141
multicellular organismal aging GO:0010259 812 0.140
Worm
regulation of cellular component size GO:0032535 40 0.137
reproductive system development GO:0061458 850 0.137
phosphate containing compound metabolic process GO:0006796 232 0.133
nucleobase containing compound biosynthetic process GO:0034654 184 0.132
Worm
sexual reproduction GO:0019953 546 0.131
cellular protein metabolic process GO:0044267 279 0.130
organelle organization GO:0006996 783 0.128
regulation of locomotion GO:0040012 161 0.127
multicellular organismal reproductive process GO:0048609 815 0.127
biosynthetic process GO:0009058 323 0.126
Worm
regulation of macromolecule metabolic process GO:0060255 421 0.123
Worm
cellular nitrogen compound biosynthetic process GO:0044271 192 0.123
Worm
inductive cell migration GO:0040039 145 0.119
macromolecule localization GO:0033036 771 0.117
Worm
negative regulation of cellular process GO:0048523 239 0.116
Worm
macromolecule modification GO:0043412 218 0.116
locomotion GO:0040011 1634 0.115
single organism signaling GO:0044700 401 0.114
Worm
pronuclear migration GO:0035046 51 0.113
regulation of response to stimulus GO:0048583 243 0.113
Worm
cellular macromolecule biosynthetic process GO:0034645 247 0.112
Worm
sex differentiation GO:0007548 909 0.110
single fertilization GO:0007338 61 0.109
regulation of developmental process GO:0050793 684 0.108
single organism reproductive process GO:0044702 1196 0.107
tube development GO:0035295 126 0.106
multi organism reproductive process GO:0044703 867 0.101
cellular component morphogenesis GO:0032989 318 0.100
rna biosynthetic process GO:0032774 169 0.098
Worm
vulval development GO:0040025 333 0.097
Worm
rna metabolic process GO:0016070 228 0.095
Worm
regulation of nitrogen compound metabolic process GO:0051171 222 0.094
Worm
establishment of nucleus localization GO:0040023 55 0.092
gamete generation GO:0007276 461 0.092
negative regulation of metabolic process GO:0009892 240 0.091
Worm
negative regulation of macromolecule metabolic process GO:0010605 229 0.090
Worm
body morphogenesis GO:0010171 620 0.089
Worm
tube morphogenesis GO:0035239 79 0.088
negative regulation of biological process GO:0048519 567 0.088
Worm
programmed cell death GO:0012501 500 0.085
neuron differentiation GO:0030182 217 0.084
death GO:0016265 547 0.082
gastrulation GO:0007369 58 0.082
female gamete generation GO:0007292 254 0.078
gene expression GO:0010467 412 0.078
Worm
reproductive structure development GO:0048608 850 0.076
signal transduction GO:0007165 317 0.076
Worm
regulation of biological quality GO:0065008 741 0.076
Worm
organic substance biosynthetic process GO:1901576 323 0.075
Worm
oviposition GO:0018991 364 0.075
regulation of phosphorus metabolic process GO:0051174 81 0.075
positive regulation of macromolecule metabolic process GO:0010604 149 0.074
protein complex assembly GO:0006461 186 0.073
cell division GO:0051301 262 0.073
protein phosphorylation GO:0006468 85 0.073
regulation of cellular protein metabolic process GO:0032268 75 0.073
membrane organization GO:0061024 135 0.072
Worm
meiotic cell cycle GO:0051321 335 0.072
anatomical structure formation involved in morphogenesis GO:0048646 250 0.070
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.070
digestive tract morphogenesis GO:0048546 76 0.070
positive regulation of developmental growth GO:0048639 354 0.069
maintenance of location GO:0051235 580 0.068
Worm
reproductive behavior GO:0019098 387 0.068
regulation of phosphorylation GO:0042325 45 0.067
protein metabolic process GO:0019538 422 0.066
protein complex subunit organization GO:0071822 280 0.066
developmental growth GO:0048589 412 0.066
regulation of biosynthetic process GO:0009889 189 0.065
Worm
phosphorylation GO:0016310 116 0.065
multicellular organismal reproductive behavior GO:0033057 384 0.065
head development GO:0060322 1 0.064
growth GO:0040007 562 0.064
embryonic morphogenesis GO:0048598 152 0.064
regulation of rna biosynthetic process GO:2001141 165 0.063
Worm
nucleus localization GO:0051647 55 0.061
lipid localization GO:0010876 573 0.061
Worm
regulation of localization GO:0032879 194 0.059
mitotic cell cycle process GO:1903047 194 0.059
regulation of primary metabolic process GO:0080090 292 0.059
Worm
lipid storage GO:0019915 565 0.059
Worm
cytoskeleton organization GO:0007010 339 0.058
tissue morphogenesis GO:0048729 65 0.058
positive regulation of multicellular organismal process GO:0051240 417 0.057
regulation of phosphate metabolic process GO:0019220 81 0.057
single organism localization GO:1902578 518 0.057
Worm
positive regulation of nucleic acid templated transcription GO:1903508 102 0.056
negative regulation of neurogenesis GO:0050768 4 0.054
positive regulation of rna metabolic process GO:0051254 103 0.054
macromolecule biosynthetic process GO:0009059 250 0.054
Worm
regulation of organelle organization GO:0033043 164 0.054
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.053
cellular localization GO:0051641 360 0.053
oogenesis GO:0048477 229 0.053
positive regulation of cellular catabolic process GO:0031331 35 0.052
macromolecular complex assembly GO:0065003 193 0.052
transport GO:0006810 1093 0.052
Worm
protein complex biogenesis GO:0070271 186 0.051
multicellular organism growth GO:0035264 385 0.051
positive regulation of cellular metabolic process GO:0031325 178 0.050
regulation of post embryonic development GO:0048580 260 0.048
cellular ketone metabolic process GO:0042180 14 0.048
macromolecular complex subunit organization GO:0043933 320 0.048
cell part morphogenesis GO:0032990 152 0.048
nucleic acid metabolic process GO:0090304 299 0.047
Worm
regulation of cellular component organization GO:0051128 248 0.047
apoptotic process GO:0006915 478 0.046
post embryonic organ development GO:0048569 336 0.046
Worm
regulation of cell motility GO:2000145 57 0.045
regulation of anatomical structure size GO:0090066 46 0.045
organ morphogenesis GO:0009887 67 0.045
cell death GO:0008219 547 0.044
positive regulation of developmental process GO:0051094 408 0.044
protein localization GO:0008104 205 0.044
system process GO:0003008 136 0.044
regulation of cellular metabolic process GO:0031323 305 0.044
Worm
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.043
Worm
negative regulation of developmental process GO:0051093 227 0.042
response to chemical GO:0042221 356 0.041
Worm
regulation of developmental growth GO:0048638 389 0.041
behavior GO:0007610 527 0.041
regulation of cell cycle process GO:0010564 145 0.040
cellular component assembly GO:0022607 293 0.040
cellular component biogenesis GO:0044085 297 0.040
small molecule metabolic process GO:0044281 186 0.040
generation of neurons GO:0048699 235 0.039
asymmetric cell division GO:0008356 36 0.039
regulation of multicellular organism growth GO:0040014 373 0.038
regulation of cell migration GO:0030334 55 0.038
cellular protein complex assembly GO:0043623 178 0.038
organelle localization GO:0051640 127 0.038
chromosome segregation GO:0007059 180 0.038
response to external stimulus GO:0009605 289 0.038
multi organism reproductive behavior GO:0044705 387 0.037
negative regulation of cellular protein metabolic process GO:0032269 27 0.037
regulation of cellular component movement GO:0051270 62 0.037
positive regulation of catabolic process GO:0009896 38 0.036
single organism cellular localization GO:1902580 72 0.036
positive regulation of neurogenesis GO:0050769 4 0.036
digestive tract development GO:0048565 122 0.036
neuron recognition GO:0008038 83 0.036
immune response GO:0006955 192 0.036
negative regulation of gene expression GO:0010629 217 0.035
Worm
catabolic process GO:0009056 318 0.035
sensory organ morphogenesis GO:0090596 2 0.035
regulation of transcription dna templated GO:0006355 164 0.035
Worm
posttranscriptional regulation of gene expression GO:0010608 166 0.035
positive regulation of multicellular organism growth GO:0040018 352 0.035
epidermis development GO:0008544 24 0.035
establishment of localization in cell GO:0051649 318 0.034
regulation of multicellular organismal process GO:0051239 726 0.034
signaling GO:0023052 401 0.033
Worm
regulation of growth GO:0040008 409 0.033
meiotic chromosome segregation GO:0045132 139 0.032
regulation of cellular ketone metabolic process GO:0010565 3 0.031
cellular macromolecular complex assembly GO:0034622 184 0.031
cell morphogenesis GO:0000902 163 0.031
nuclear migration GO:0007097 54 0.031
neurological system process GO:0050877 53 0.031
negative regulation of multicellular organismal process GO:0051241 236 0.031
positive regulation of gene expression GO:0010628 112 0.031
digestive system development GO:0055123 122 0.030
negative regulation of nematode larval development GO:0061064 208 0.030
cellular catabolic process GO:0044248 199 0.030
cell fate commitment GO:0045165 139 0.029
regulation of signal transduction GO:0009966 135 0.029
Worm
secretion by cell GO:0032940 138 0.028
single organism organelle organization GO:1902589 501 0.028
cell cycle process GO:0022402 482 0.028
posttranscriptional gene silencing by rna GO:0035194 143 0.028
organic acid metabolic process GO:0006082 47 0.028
negative regulation of post embryonic development GO:0048581 208 0.028
epithelium development GO:0060429 68 0.028
regulation of cell communication GO:0010646 176 0.028
Worm
peptidyl tyrosine phosphorylation GO:0018108 2 0.028
regulation of molecular function GO:0065009 89 0.028
fertilization GO:0009566 63 0.027
posttranscriptional gene silencing GO:0016441 143 0.027
defense response GO:0006952 296 0.027
regulation of cell division GO:0051302 142 0.026
positive regulation of cellular biosynthetic process GO:0031328 109 0.026
dauer larval development GO:0040024 92 0.026
axonogenesis GO:0007409 102 0.026
cuticle development GO:0042335 100 0.026
Worm
regulation of catalytic activity GO:0050790 78 0.026
positive regulation of biosynthetic process GO:0009891 109 0.026
regulation of multicellular organismal development GO:2000026 317 0.025
cell recognition GO:0008037 85 0.025
regulation of protein kinase activity GO:0045859 28 0.025
regulation of kinase activity GO:0043549 29 0.025
multi multicellular organism process GO:0044706 390 0.025
regulation of cell proliferation GO:0042127 105 0.024
carbohydrate derivative metabolic process GO:1901135 141 0.024
regulation of macromolecule biosynthetic process GO:0010556 189 0.024
Worm
wnt signaling pathway GO:0016055 27 0.024
cell projection morphogenesis GO:0048858 148 0.023
carbohydrate derivative biosynthetic process GO:1901137 46 0.023
response to wounding GO:0009611 4 0.023
regulation of protein modification process GO:0031399 46 0.023
cell proliferation GO:0008283 116 0.023
neurogenesis GO:0022008 236 0.023
spermatogenesis GO:0007283 41 0.023
regulation of vulval development GO:0040028 248 0.023
regulation of organ morphogenesis GO:2000027 4 0.023
microtubule based process GO:0007017 182 0.022
regulation of protein metabolic process GO:0051246 81 0.022
male gamete generation GO:0048232 41 0.022
regulation of meiotic cell cycle GO:0051445 136 0.022
cellular response to stress GO:0033554 162 0.022
oxoacid metabolic process GO:0043436 47 0.022
neuron projection morphogenesis GO:0048812 114 0.022
positive regulation of cellular protein catabolic process GO:1903364 3 0.022
ectoderm development GO:0007398 3 0.021
carbohydrate metabolic process GO:0005975 34 0.021
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.021
carboxylic acid metabolic process GO:0019752 34 0.021
organic substance transport GO:0071702 113 0.021
response to other organism GO:0051707 101 0.021
cell morphogenesis involved in differentiation GO:0000904 112 0.021
pattern specification process GO:0007389 59 0.021
axon development GO:0061564 163 0.021
ribonucleoprotein complex assembly GO:0022618 4 0.020
positive regulation of growth GO:0045927 369 0.020
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.020
Worm
cell substrate adhesion GO:0031589 1 0.020
positive regulation of phosphorylation GO:0042327 27 0.020
cellular amine metabolic process GO:0044106 15 0.020
cellular macromolecule catabolic process GO:0044265 73 0.020
regulation of transferase activity GO:0051338 31 0.020
regulation of multi organism process GO:0043900 69 0.019
organonitrogen compound metabolic process GO:1901564 151 0.019
secretion GO:0046903 147 0.019
establishment of organelle localization GO:0051656 123 0.019
protein modification by small protein conjugation or removal GO:0070647 40 0.019
nervous system development GO:0007399 253 0.019
regulation of cellular amine metabolic process GO:0033238 0 0.018
axonal fasciculation GO:0007413 79 0.018
regulation of cytoplasmic transport GO:1903649 3 0.018
regulation of apoptotic signaling pathway GO:2001233 1 0.018
cell type specific apoptotic process GO:0097285 4 0.018
gene silencing by rna GO:0031047 143 0.017
organelle assembly GO:0070925 214 0.017
membrane invagination GO:0010324 98 0.017
Worm
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 1 0.017
spindle localization GO:0051653 51 0.017
actin filament based process GO:0030029 191 0.017
actomyosin structure organization GO:0031032 154 0.017
regulation of mitotic cell cycle GO:0007346 76 0.017
muscle cell development GO:0055001 158 0.017
negative regulation of signal transduction GO:0009968 60 0.017
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.017
single organism carbohydrate metabolic process GO:0044723 29 0.016
organic substance catabolic process GO:1901575 294 0.016
peptidyl amino acid modification GO:0018193 58 0.016
innate immune response GO:0045087 190 0.016
taxis GO:0042330 128 0.016
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.016
Worm
chromatin assembly or disassembly GO:0006333 1 0.016
canonical wnt signaling pathway GO:0060070 3 0.016
regulation of nematode larval development GO:0061062 260 0.016
regulation of cell size GO:0008361 30 0.016
single organism biosynthetic process GO:0044711 91 0.015
regulation of protein import into nucleus GO:0042306 3 0.015
multi organism behavior GO:0051705 389 0.015
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.015
female meiotic division GO:0007143 17 0.015
nucleus organization GO:0006997 38 0.015
organelle fission GO:0048285 363 0.015
single organism catabolic process GO:0044712 129 0.015
regulation of cellular biosynthetic process GO:0031326 189 0.015
Worm
regulation of canonical wnt signaling pathway GO:0060828 1 0.015
meiotic cell cycle process GO:1903046 170 0.015
positive regulation of chromosome organization GO:2001252 2 0.014
cell cycle GO:0007049 526 0.014
positive regulation of phosphorus metabolic process GO:0010562 56 0.014
regulation of rna metabolic process GO:0051252 173 0.014
Worm
response to organic substance GO:0010033 131 0.014
Worm
aromatic compound catabolic process GO:0019439 116 0.014
regulation of signaling GO:0023051 172 0.014
Worm
regulation of nucleocytoplasmic transport GO:0046822 3 0.014
cell maturation GO:0048469 26 0.014
negative regulation of rna biosynthetic process GO:1902679 53 0.014
Worm
muscle tissue development GO:0060537 1 0.014
negative regulation of signaling GO:0023057 61 0.014
positive regulation of phosphate metabolic process GO:0045937 56 0.014
response to external biotic stimulus GO:0043207 101 0.014
positive regulation of neuron differentiation GO:0045666 4 0.014
cytoskeleton dependent cytokinesis GO:0061640 35 0.014
actin cytoskeleton organization GO:0030036 184 0.014
regulation of catabolic process GO:0009894 57 0.014
dendrite development GO:0016358 42 0.013
response to abiotic stimulus GO:0009628 152 0.013
cellular protein localization GO:0034613 75 0.013
single organism membrane organization GO:0044802 35 0.013
regulation of jun kinase activity GO:0043506 3 0.013
cellular nitrogen compound catabolic process GO:0044270 119 0.013
molting cycle GO:0042303 281 0.013
macromolecule catabolic process GO:0009057 202 0.013
regulation of behavior GO:0050795 97 0.013
amine metabolic process GO:0009308 15 0.013
cellular amino acid metabolic process GO:0006520 15 0.013
apoptotic cell clearance GO:0043277 111 0.013
Worm
homeostatic process GO:0042592 51 0.012
mitotic cell cycle phase transition GO:0044772 13 0.012
striated muscle myosin thick filament assembly GO:0071688 138 0.012
muscle structure development GO:0061061 191 0.012
meiotic nuclear division GO:0007126 300 0.012
regulation of epithelial cell proliferation GO:0050678 1 0.012
positive regulation of protein metabolic process GO:0051247 45 0.012
regulation of cell development GO:0060284 49 0.012
negative regulation of response to external stimulus GO:0032102 3 0.012
oocyte differentiation GO:0009994 45 0.012
peptidyl tyrosine modification GO:0018212 3 0.012
intracellular transport GO:0046907 77 0.012
skeletal muscle organ development GO:0060538 3 0.012
small gtpase mediated signal transduction GO:0007264 32 0.012
response to biotic stimulus GO:0009607 101 0.012
detection of external stimulus GO:0009581 4 0.012
regulation of epithelial cell differentiation GO:0030856 4 0.012
cellular response to organic substance GO:0071310 119 0.012
Worm
positive regulation of cellular component organization GO:0051130 34 0.011
negative regulation of response to stimulus GO:0048585 73 0.011
phagocytosis GO:0006909 115 0.011
Worm
regulation of cell projection organization GO:0031344 38 0.011
ras protein signal transduction GO:0007265 31 0.011
regulation of reproductive process GO:2000241 66 0.011
nucleobase containing compound catabolic process GO:0034655 114 0.011
protein modification by small protein conjugation GO:0032446 31 0.011
organophosphate catabolic process GO:0046434 81 0.011
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 2 0.011
myosin filament organization GO:0031033 138 0.011
protein oligomerization GO:0051259 4 0.011
regulation of intracellular signal transduction GO:1902531 77 0.011
male anatomical structure morphogenesis GO:0090598 78 0.011
myofibril assembly GO:0030239 154 0.010
oocyte development GO:0048599 44 0.010
cellular component assembly involved in morphogenesis GO:0010927 183 0.010

ptr-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.018
disease of metabolism DOID:0014667 0 0.010