Caenorhabditis elegans

17 known processes

smf-2 (CELE_K11G12.3)

Protein SMF-2

smf-2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
phosphorus metabolic process GO:0006793 232 0.153
Mouse
vesicle mediated transport GO:0016192 852 0.147
Mouse
endocytosis GO:0006897 819 0.145
Mouse
death GO:0016265 547 0.130
Human
response to wounding GO:0009611 4 0.124
Mouse
generation of neurons GO:0048699 235 0.115
Mouse
apoptotic process GO:0006915 478 0.114
Human
cell death GO:0008219 547 0.113
Human
cell development GO:0048468 696 0.106
Mouse
behavior GO:0007610 527 0.105
Mouse
establishment of localization GO:0051234 1171 0.104
Human Mouse
macromolecule localization GO:0033036 771 0.103
Mouse
single organism transport GO:0044765 447 0.103
Human Mouse
transport GO:0006810 1093 0.099
Human Mouse
organ development GO:0048513 1102 0.098
Mouse
regulation of biological quality GO:0065008 741 0.096
cell morphogenesis GO:0000902 163 0.094
Mouse
anion transport GO:0006820 30 0.092
Mouse
cell projection morphogenesis GO:0048858 148 0.086
Mouse
phosphorylation GO:0016310 116 0.086
Mouse
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.085
Mouse
embryo development ending in birth or egg hatching GO:0009792 2992 0.085
nervous system development GO:0007399 253 0.082
Mouse
ion transmembrane transport GO:0034220 91 0.081
Human Mouse
regulation of multicellular organismal process GO:0051239 726 0.080
Mouse
regulation of macromolecule metabolic process GO:0060255 421 0.078
Human Mouse
embryo development GO:0009790 3052 0.078
neurogenesis GO:0022008 236 0.074
Mouse
neuron differentiation GO:0030182 217 0.073
Mouse
neuron projection morphogenesis GO:0048812 114 0.073
Mouse
regulation of metabolic process GO:0019222 478 0.071
Human Mouse
positive regulation of multicellular organismal process GO:0051240 417 0.071
Mouse
defense response to other organism GO:0098542 100 0.070
Mouse
protein modification process GO:0036211 207 0.070
Mouse
regulation of cellular component organization GO:0051128 248 0.069
Mouse
negative regulation of multicellular organismal process GO:0051241 236 0.069
Mouse
protein metabolic process GO:0019538 422 0.067
Human Mouse
cellular component morphogenesis GO:0032989 318 0.067
Mouse
locomotion GO:0040011 1634 0.066
lipid localization GO:0010876 573 0.066
maintenance of location GO:0051235 580 0.065
organonitrogen compound metabolic process GO:1901564 151 0.064
Mouse
single organism localization GO:1902578 518 0.064
Human Mouse
defense response to gram negative bacterium GO:0050829 64 0.064
Mouse
protein localization GO:0008104 205 0.063
Mouse
lipid storage GO:0019915 565 0.062
positive regulation of cellular process GO:0048522 332 0.061
Human Mouse
regulation of phosphate metabolic process GO:0019220 81 0.061
Mouse
establishment of localization in cell GO:0051649 318 0.061
Mouse
defense response to bacterium GO:0042742 86 0.061
Mouse
cellular localization GO:0051641 360 0.060
Mouse
cell projection organization GO:0030030 231 0.060
Mouse
gene expression GO:0010467 412 0.060
Human Mouse
cell morphogenesis involved in differentiation GO:0000904 112 0.059
Mouse
multicellular organismal aging GO:0010259 812 0.059
system process GO:0003008 136 0.058
Mouse
regulation of cellular metabolic process GO:0031323 305 0.057
Human Mouse
determination of adult lifespan GO:0008340 812 0.057
aging GO:0007568 812 0.053
regulation of phosphorus metabolic process GO:0051174 81 0.053
Mouse
posttranscriptional regulation of gene expression GO:0010608 166 0.050
Mouse
response to other organism GO:0051707 101 0.050
Mouse
post embryonic development GO:0009791 2152 0.050
protein phosphorylation GO:0006468 85 0.050
Mouse
cellular response to stress GO:0033554 162 0.049
Human
single organism biosynthetic process GO:0044711 91 0.049
Mouse
defense response GO:0006952 296 0.048
Mouse
cellular protein modification process GO:0006464 207 0.048
Mouse
neuron development GO:0048666 199 0.047
Mouse
positive regulation of catalytic activity GO:0043085 59 0.046
Human Mouse
single organism behavior GO:0044708 83 0.046
Mouse
response to abiotic stimulus GO:0009628 152 0.045
Human
organelle organization GO:0006996 783 0.045
cellular response to chemical stimulus GO:0070887 129 0.045
Human
cation transmembrane transport GO:0098655 59 0.045
Human Mouse
regulation of protein metabolic process GO:0051246 81 0.044
Human Mouse
multicellular organismal reproductive process GO:0048609 815 0.044
cognition GO:0050890 27 0.044
Mouse
multi organism reproductive process GO:0044703 867 0.044
organonitrogen compound biosynthetic process GO:1901566 44 0.044
Mouse
hermaphrodite genitalia development GO:0040035 734 0.044
biosynthetic process GO:0009058 323 0.044
Mouse
regulation of developmental process GO:0050793 684 0.042
carboxylic acid transport GO:0046942 15 0.041
Mouse
nucleobase containing compound metabolic process GO:0006139 406 0.041
Mouse
cell proliferation GO:0008283 116 0.041
Mouse
receptor mediated endocytosis GO:0006898 715 0.040
positive regulation of phosphate metabolic process GO:0045937 56 0.040
Mouse
regulation of localization GO:0032879 194 0.040
Mouse
cation transport GO:0006812 78 0.040
Human Mouse
catabolic process GO:0009056 318 0.040
regulation of growth GO:0040008 409 0.040
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.039
Mouse
response to organic substance GO:0010033 131 0.039
Mouse
positive regulation of cellular metabolic process GO:0031325 178 0.038
Human Mouse
phagocytosis GO:0006909 115 0.038
Mouse
regulation of phosphorylation GO:0042325 45 0.038
Mouse
organic substance biosynthetic process GO:1901576 323 0.037
Mouse
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.037
Mouse
growth GO:0040007 562 0.036
cellular biosynthetic process GO:0044249 315 0.035
Mouse
programmed cell death GO:0012501 500 0.035
Human
developmental growth GO:0048589 412 0.035
response to external biotic stimulus GO:0043207 101 0.034
Mouse
negative regulation of biological process GO:0048519 567 0.034
Mouse
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.033
Mouse
response to bacterium GO:0009617 86 0.033
Mouse
reproductive behavior GO:0019098 387 0.033
single organism signaling GO:0044700 401 0.033
regulation of catalytic activity GO:0050790 78 0.032
Human Mouse
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.031
Mouse
dendrite development GO:0016358 42 0.031
Mouse
regulation of primary metabolic process GO:0080090 292 0.031
Human Mouse
multi organism behavior GO:0051705 389 0.031
cellular protein localization GO:0034613 75 0.030
Mouse
multi organism reproductive behavior GO:0044705 387 0.030
multicellular organism reproduction GO:0032504 819 0.030
response to oxygen levels GO:0070482 22 0.030
Human
organic substance transport GO:0071702 113 0.030
Mouse
aromatic compound biosynthetic process GO:0019438 192 0.029
Mouse
positive regulation of molecular function GO:0044093 61 0.029
Human Mouse
organic substance catabolic process GO:1901575 294 0.029
gonad development GO:0008406 840 0.029
response to chemical GO:0042221 356 0.029
reproductive system development GO:0061458 850 0.029
reproductive structure development GO:0048608 850 0.029
regulation of cellular protein metabolic process GO:0032268 75 0.028
Human Mouse
regulation of multicellular organism growth GO:0040014 373 0.028
positive regulation of cellular biosynthetic process GO:0031328 109 0.028
Mouse
divalent inorganic cation transport GO:0072511 17 0.028
Human Mouse
genitalia development GO:0048806 741 0.028
regulation of transport GO:0051049 91 0.028
Mouse
cellular component assembly GO:0022607 293 0.027
positive regulation of gene expression GO:0010628 112 0.027
Mouse
single organism organelle organization GO:1902589 501 0.027
single organism reproductive process GO:0044702 1196 0.027
developmental process involved in reproduction GO:0003006 1165 0.027
regulation of endocytosis GO:0030100 25 0.027
Mouse
sex differentiation GO:0007548 909 0.027
regulation of molecular function GO:0065009 89 0.027
Human Mouse
heterocycle biosynthetic process GO:0018130 187 0.026
Mouse
positive regulation of growth GO:0045927 369 0.026
cellular component biogenesis GO:0044085 297 0.026
macromolecular complex subunit organization GO:0043933 320 0.026
multicellular organism growth GO:0035264 385 0.026
positive regulation of protein metabolic process GO:0051247 45 0.026
Human Mouse
body morphogenesis GO:0010171 620 0.026
cellular macromolecule biosynthetic process GO:0034645 247 0.026
Mouse
cellular protein metabolic process GO:0044267 279 0.026
Human Mouse
multi multicellular organism process GO:0044706 390 0.026
cytoskeleton organization GO:0007010 339 0.026
development of primary sexual characteristics GO:0045137 840 0.025
positive regulation of metabolic process GO:0009893 187 0.025
Human Mouse
regulation of developmental growth GO:0048638 389 0.025
positive regulation of developmental growth GO:0048639 354 0.024
immune response GO:0006955 192 0.024
Mouse
positive regulation of biosynthetic process GO:0009891 109 0.024
Mouse
positive regulation of nucleic acid templated transcription GO:1903508 102 0.024
Mouse
inorganic cation transmembrane transport GO:0098662 46 0.024
Human Mouse
small molecule metabolic process GO:0044281 186 0.024
cellular macromolecule localization GO:0070727 75 0.024
Mouse
localization of cell GO:0051674 313 0.024
macromolecule modification GO:0043412 218 0.023
Mouse
nucleobase containing compound biosynthetic process GO:0034654 184 0.023
Mouse
single organism cellular localization GO:1902580 72 0.023
Mouse
oviposition GO:0018991 364 0.023
positive regulation of multicellular organism growth GO:0040018 352 0.022
cell motility GO:0048870 313 0.022
macromolecule catabolic process GO:0009057 202 0.022
phosphate containing compound metabolic process GO:0006796 232 0.022
Mouse
learning or memory GO:0007611 27 0.022
Mouse
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.022
Mouse
positive regulation of transcription dna templated GO:0045893 102 0.022
Mouse
regulation of multicellular organismal development GO:2000026 317 0.022
monovalent inorganic cation transport GO:0015672 33 0.022
Human Mouse
cell migration GO:0016477 306 0.021
positive regulation of hydrolase activity GO:0051345 38 0.021
Human
sensory organ morphogenesis GO:0090596 2 0.021
cell cycle process GO:0022402 482 0.021
cell cycle GO:0007049 526 0.020
nucleobase containing compound catabolic process GO:0034655 114 0.020
ribose phosphate metabolic process GO:0019693 99 0.020
cellular catabolic process GO:0044248 199 0.020
response to external stimulus GO:0009605 289 0.020
Mouse
multicellular organismal reproductive behavior GO:0033057 384 0.020
positive regulation of cell death GO:0010942 38 0.019
Human
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.019
Mouse
cellular component movement GO:0006928 388 0.019
positive regulation of developmental process GO:0051094 408 0.019
pigment metabolic process GO:0042440 2 0.019
Mouse
signaling GO:0023052 401 0.019
cellular nitrogen compound catabolic process GO:0044270 119 0.019
carbohydrate derivative metabolic process GO:1901135 141 0.019
single organism intracellular transport GO:1902582 70 0.019
Mouse
gamete generation GO:0007276 461 0.018
rna metabolic process GO:0016070 228 0.018
Mouse
response to oxygen containing compound GO:1901700 44 0.018
Mouse
regulation of cellular biosynthetic process GO:0031326 189 0.018
Mouse
innate immune response GO:0045087 190 0.018
Mouse
positive regulation of protein modification process GO:0031401 29 0.018
Mouse
organelle fission GO:0048285 363 0.017
protein complex subunit organization GO:0071822 280 0.017
inductive cell migration GO:0040039 145 0.017
nucleoside phosphate metabolic process GO:0006753 108 0.017
inorganic ion transmembrane transport GO:0098660 54 0.017
Human Mouse
macromolecular complex assembly GO:0065003 193 0.017
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.017
nucleotide metabolic process GO:0009117 108 0.017
muscle structure development GO:0061061 191 0.017
metal ion transport GO:0030001 49 0.017
Human Mouse
signal transduction GO:0007165 317 0.017
purine ribonucleoside metabolic process GO:0046128 92 0.017
actin filament based process GO:0030029 191 0.017
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.017
Mouse
regulation of macromolecule biosynthetic process GO:0010556 189 0.016
Mouse
response to transition metal nanoparticle GO:1990267 18 0.016
negative regulation of developmental process GO:0051093 227 0.016
organic cyclic compound catabolic process GO:1901361 119 0.016
aromatic compound catabolic process GO:0019439 116 0.016
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.016
regulation of vulval development GO:0040028 248 0.016
regulation of post embryonic development GO:0048580 260 0.016
ribonucleoside metabolic process GO:0009119 98 0.016
regulation of response to stimulus GO:0048583 243 0.016
Mouse
single organism catabolic process GO:0044712 129 0.016
regulation of apoptotic signaling pathway GO:2001233 1 0.015
protein complex biogenesis GO:0070271 186 0.015
glycosyl compound metabolic process GO:1901657 100 0.015
muscle tissue development GO:0060537 1 0.015
response to oxidative stress GO:0006979 42 0.015
Human Worm
protein complex assembly GO:0006461 186 0.015
sexual reproduction GO:0019953 546 0.015
positive regulation of rna biosynthetic process GO:1902680 102 0.015
Mouse
regulation of protein kinase activity GO:0045859 28 0.015
Mouse
regulation of rna metabolic process GO:0051252 173 0.015
Mouse
gene silencing by rna GO:0031047 143 0.015
female gamete generation GO:0007292 254 0.015
regulation of transferase activity GO:0051338 31 0.015
Mouse
regulation of cellular ketone metabolic process GO:0010565 3 0.015
posttranscriptional gene silencing GO:0016441 143 0.015
organophosphate metabolic process GO:0019637 125 0.015
regulation of apoptotic process GO:0042981 36 0.015
Human
heterocycle catabolic process GO:0046700 119 0.015
regulation of vesicle mediated transport GO:0060627 27 0.015
Mouse
purine nucleotide metabolic process GO:0006163 95 0.015
protein catabolic process GO:0030163 162 0.015
organic cyclic compound biosynthetic process GO:1901362 195 0.015
Mouse
ribonucleoside triphosphate metabolic process GO:0009199 87 0.014
regulation of locomotion GO:0040012 161 0.014
posttranscriptional gene silencing by rna GO:0035194 143 0.014
negative regulation of metabolic process GO:0009892 240 0.014
nucleic acid templated transcription GO:0097659 169 0.014
Mouse
purine nucleoside metabolic process GO:0042278 92 0.014
positive regulation of apoptotic process GO:0043065 17 0.014
Human
pigment biosynthetic process GO:0046148 2 0.014
Mouse
regulation of cell communication GO:0010646 176 0.014
neuron projection development GO:0031175 187 0.014
Mouse
homeostatic process GO:0042592 51 0.014
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.014
germ cell development GO:0007281 351 0.014
divalent metal ion transport GO:0070838 17 0.014
Human Mouse
post embryonic organ development GO:0048569 336 0.014
skeletal muscle organ development GO:0060538 3 0.014
nucleobase containing small molecule metabolic process GO:0055086 115 0.013
rna interference GO:0016246 137 0.013
monovalent inorganic cation homeostasis GO:0055067 6 0.013
Mouse
regulation of nematode larval development GO:0061062 260 0.013
protein transport GO:0015031 45 0.013
Mouse
head development GO:0060322 1 0.013
organonitrogen compound catabolic process GO:1901565 90 0.013
regulation of cellular amine metabolic process GO:0033238 0 0.013
regulation of gene expression epigenetic GO:0040029 163 0.013
purine ribonucleotide metabolic process GO:0009150 95 0.013
regulation of cell cycle GO:0051726 194 0.013
secretion GO:0046903 147 0.013
nucleoside triphosphate metabolic process GO:0009141 87 0.013
negative regulation of macromolecule metabolic process GO:0010605 229 0.013
microtubule based process GO:0007017 182 0.013
organelle assembly GO:0070925 214 0.013
cellular component assembly involved in morphogenesis GO:0010927 183 0.013
actomyosin structure organization GO:0031032 154 0.013
ion transport GO:0006811 113 0.013
Human Mouse
cation homeostasis GO:0055080 20 0.013
cellular protein complex assembly GO:0043623 178 0.013
molting cycle GO:0042303 281 0.013
positive regulation of programmed cell death GO:0043068 27 0.013
Human
cellular amine metabolic process GO:0044106 15 0.012
anatomical structure formation involved in morphogenesis GO:0048646 250 0.012
regulation of nucleic acid templated transcription GO:1903506 165 0.012
Mouse
negative regulation of post embryonic development GO:0048581 208 0.012
adult behavior GO:0030534 3 0.012
protein oligomerization GO:0051259 4 0.012
ribonucleotide metabolic process GO:0009259 99 0.012
oogenesis GO:0048477 229 0.012
nucleoside metabolic process GO:0009116 99 0.012
ion homeostasis GO:0050801 21 0.012
cell type specific apoptotic process GO:0097285 4 0.012
positive regulation of transferase activity GO:0051347 21 0.012
Mouse
actin cytoskeleton organization GO:0030036 184 0.012
muscle cell differentiation GO:0042692 171 0.012
negative regulation of gene expression GO:0010629 217 0.012
neuron recognition GO:0008038 83 0.012
purine nucleoside triphosphate metabolic process GO:0009144 87 0.012
regulation of organelle organization GO:0033043 164 0.012
neuromuscular junction development GO:0007528 2 0.012
vulval development GO:0040025 333 0.012
response to acid chemical GO:0001101 4 0.012
synaptic transmission GO:0007268 106 0.012
transmembrane transport GO:0055085 110 0.012
Human Mouse
nucleoside catabolic process GO:0009164 78 0.012
regulation of behavior GO:0050795 97 0.012
regulation of signaling GO:0023051 172 0.012
amine metabolic process GO:0009308 15 0.012
myosin filament organization GO:0031033 138 0.011
cellular macromolecular complex assembly GO:0034622 184 0.011
protein localization to organelle GO:0033365 37 0.011
Mouse
purine containing compound metabolic process GO:0072521 95 0.011
cell cell signaling GO:0007267 118 0.011
negative regulation of cellular process GO:0048523 239 0.011
establishment of protein localization to membrane GO:0090150 3 0.011
rna localization GO:0006403 3 0.011
nucleoside triphosphate catabolic process GO:0009143 72 0.011
gene silencing GO:0016458 143 0.011
nucleotide catabolic process GO:0009166 77 0.011
regulation of cellular amino acid metabolic process GO:0006521 0 0.011
negative regulation of nematode larval development GO:0061064 208 0.011
ribonucleotide catabolic process GO:0009261 75 0.011
muscle cell development GO:0055001 158 0.011
carbohydrate derivative catabolic process GO:1901136 82 0.011
axonal fasciculation GO:0007413 79 0.011
cellular homeostasis GO:0019725 22 0.011
Mouse
response to biotic stimulus GO:0009607 101 0.011
Mouse
cell part morphogenesis GO:0032990 152 0.011
Mouse
cell recognition GO:0008037 85 0.011
activation of protein kinase activity GO:0032147 11 0.011
Mouse
regulation of synapse assembly GO:0051963 2 0.011
regulation of response to wounding GO:1903034 1 0.011
axon development GO:0061564 163 0.010
striated muscle cell development GO:0055002 157 0.010
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.010
cellular ketone metabolic process GO:0042180 14 0.010
positive regulation of cellular component organization GO:0051130 34 0.010
Mouse
regulation of gene expression GO:0010468 366 0.010
Mouse
regulation of multi organism process GO:0043900 69 0.010
cellular response to topologically incorrect protein GO:0035967 76 0.010
cellular response to unfolded protein GO:0034620 71 0.010
regulation of protein modification process GO:0031399 46 0.010
Mouse
cellular response to organic substance GO:0071310 119 0.010

smf-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.073
Human
immune system disease DOID:2914 0 0.021
Human
anemia DOID:2355 0 0.021
Human
hematopoietic system disease DOID:74 0 0.021
Human
nervous system disease DOID:863 0 0.010