Caenorhabditis elegans

19 known processes

ape-1 (CELE_F46F3.4)

Protein APE-1

ape-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organic substance catabolic process GO:1901575 294 0.560
body morphogenesis GO:0010171 620 0.515
phosphorus metabolic process GO:0006793 232 0.403
locomotion GO:0040011 1634 0.336
single organism organelle organization GO:1902589 501 0.322
organelle organization GO:0006996 783 0.320
phosphate containing compound metabolic process GO:0006796 232 0.304
organ development GO:0048513 1102 0.267
Mouse
response to anesthetic GO:0072347 1 0.212
protein complex subunit organization GO:0071822 280 0.186
embryo development GO:0009790 3052 0.168
Mouse
signal transduction GO:0007165 317 0.164
death GO:0016265 547 0.160
multicellular organismal reproductive process GO:0048609 815 0.158
catabolic process GO:0009056 318 0.153
establishment of localization GO:0051234 1171 0.150
macromolecule catabolic process GO:0009057 202 0.148
positive regulation of macromolecule metabolic process GO:0010604 149 0.143
embryo development ending in birth or egg hatching GO:0009792 2992 0.138
Mouse
intercellular transport GO:0010496 1 0.134
localization of cell GO:0051674 313 0.133
transport GO:0006810 1093 0.131
signaling GO:0023052 401 0.130
single organism transport GO:0044765 447 0.127
cell division GO:0051301 262 0.127
protein phosphorylation GO:0006468 85 0.125
cell death GO:0008219 547 0.124
actin filament based process GO:0030029 191 0.121
vesicle mediated transport GO:0016192 852 0.120
regulation of cell migration GO:0030334 55 0.119
actin cytoskeleton organization GO:0030036 184 0.118
cell cycle process GO:0022402 482 0.117
nervous system development GO:0007399 253 0.115
Mouse
cellular component morphogenesis GO:0032989 318 0.110
regulation of multicellular organismal process GO:0051239 726 0.108
protein complex assembly GO:0006461 186 0.107
positive regulation of cellular process GO:0048522 332 0.106
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.105
macromolecule localization GO:0033036 771 0.098
regulation of phosphate metabolic process GO:0019220 81 0.097
inactivation of mapkkk activity GO:0051390 2 0.096
multicellular organism reproduction GO:0032504 819 0.095
cellular component movement GO:0006928 388 0.095
single organism signaling GO:0044700 401 0.092
positive regulation of locomotion GO:0040017 42 0.088
phosphorylation GO:0016310 116 0.088
enzyme linked receptor protein signaling pathway GO:0007167 50 0.086
regulation of catabolic process GO:0009894 57 0.085
cellular localization GO:0051641 360 0.084
single organism localization GO:1902578 518 0.084
cellular macromolecular complex assembly GO:0034622 184 0.083
aging GO:0007568 812 0.083
post embryonic development GO:0009791 2152 0.081
response to external stimulus GO:0009605 289 0.081
lipid localization GO:0010876 573 0.081
apoptotic process GO:0006915 478 0.081
multi organism reproductive process GO:0044703 867 0.080
positive regulation of cell migration GO:0030335 3 0.078
regulation of organelle organization GO:0033043 164 0.077
receptor mediated endocytosis GO:0006898 715 0.077
organelle fission GO:0048285 363 0.075
endocytosis GO:0006897 819 0.075
sister chromatid segregation GO:0000819 46 0.074
positive regulation of developmental process GO:0051094 408 0.073
cellular component biogenesis GO:0044085 297 0.073
regulation of response to stimulus GO:0048583 243 0.073
nucleobase containing compound catabolic process GO:0034655 114 0.073
protein catabolic process GO:0030163 162 0.072
regulation of biological quality GO:0065008 741 0.072
multi organism behavior GO:0051705 389 0.072
regulation of phosphorus metabolic process GO:0051174 81 0.070
lipid storage GO:0019915 565 0.070
regulation of cellular component organization GO:0051128 248 0.069
cell migration GO:0016477 306 0.068
cytoskeleton organization GO:0007010 339 0.068
regulation of primary metabolic process GO:0080090 292 0.067
cellular component assembly GO:0022607 293 0.066
maintenance of location GO:0051235 580 0.065
neuron differentiation GO:0030182 217 0.064
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 34 0.063
regulation of developmental process GO:0050793 684 0.063
positive regulation of rna metabolic process GO:0051254 103 0.061
cellular biosynthetic process GO:0044249 315 0.061
generation of neurons GO:0048699 235 0.060
behavior GO:0007610 527 0.060
cellular catabolic process GO:0044248 199 0.058
response to biotic stimulus GO:0009607 101 0.057
growth GO:0040007 562 0.056
protein complex biogenesis GO:0070271 186 0.055
nucleotide metabolic process GO:0009117 108 0.055
chromosome segregation GO:0007059 180 0.055
cell motility GO:0048870 313 0.054
immune response GO:0006955 192 0.054
tissue development GO:0009888 112 0.053
cellular component assembly involved in morphogenesis GO:0010927 183 0.052
calcium mediated signaling GO:0019722 3 0.052
regulation of cellular metabolic process GO:0031323 305 0.052
single organism catabolic process GO:0044712 129 0.052
cellular protein metabolic process GO:0044267 279 0.051
head development GO:0060322 1 0.051
cell part morphogenesis GO:0032990 152 0.051
multi multicellular organism process GO:0044706 390 0.050
single organism intracellular transport GO:1902582 70 0.050
regulation of defecation rhythm GO:2000746 3 0.049
negative regulation of biological process GO:0048519 567 0.048
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.047
regulation of metabolic process GO:0019222 478 0.047
programmed cell death GO:0012501 500 0.047
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.046
gastrulation GO:0007369 58 0.046
multicellular organismal aging GO:0010259 812 0.045
organophosphate catabolic process GO:0046434 81 0.045
regulation of cell motility GO:2000145 57 0.045
muscle cell differentiation GO:0042692 171 0.044
purine ribonucleoside metabolic process GO:0046128 92 0.044
cell cell signaling GO:0007267 118 0.044
macromolecular complex subunit organization GO:0043933 320 0.043
carbohydrate derivative catabolic process GO:1901136 82 0.043
regulation of signaling GO:0023051 172 0.043
sexual reproduction GO:0019953 546 0.043
multi organism reproductive behavior GO:0044705 387 0.042
regulation of cellular catabolic process GO:0031329 51 0.042
cellular protein complex assembly GO:0043623 178 0.041
regulation of catalytic activity GO:0050790 78 0.041
defecation rhythm GO:0035882 3 0.041
cell cycle GO:0007049 526 0.041
negative regulation of protein serine threonine kinase activity GO:0071901 6 0.040
macromolecule modification GO:0043412 218 0.039
regulation of gene expression GO:0010468 366 0.039
determination of adult lifespan GO:0008340 812 0.038
regulation of macromolecule metabolic process GO:0060255 421 0.038
development of primary sexual characteristics GO:0045137 840 0.038
regulation of molecular function GO:0065009 89 0.038
response to chemical GO:0042221 356 0.037
negative regulation of cation channel activity GO:2001258 2 0.037
organophosphate metabolic process GO:0019637 125 0.036
endosomal transport GO:0016197 26 0.036
actomyosin structure organization GO:0031032 154 0.036
ribonucleoside metabolic process GO:0009119 98 0.036
regulation of locomotion GO:0040012 161 0.035
peptidyl serine modification GO:0018209 20 0.034
positive regulation of multicellular organismal process GO:0051240 417 0.034
ion transport GO:0006811 113 0.034
negative regulation of transmembrane transport GO:0034763 3 0.034
glycosyl compound metabolic process GO:1901657 100 0.034
regulation of organ morphogenesis GO:2000027 4 0.033
positive regulation of transcription dna templated GO:0045893 102 0.033
regulation of localization GO:0032879 194 0.032
oviposition GO:0018991 364 0.032
macromolecular complex assembly GO:0065003 193 0.031
positive regulation of multicellular organism growth GO:0040018 352 0.031
establishment of localization in cell GO:0051649 318 0.031
reproductive behavior GO:0019098 387 0.031
negative regulation of ion transmembrane transport GO:0034766 3 0.031
regulation of multicellular organism growth GO:0040014 373 0.031
organic substance biosynthetic process GO:1901576 323 0.031
striated muscle cell differentiation GO:0051146 158 0.031
positive regulation of rna biosynthetic process GO:1902680 102 0.031
ribonucleoside triphosphate catabolic process GO:0009203 72 0.031
ribonucleoside catabolic process GO:0042454 77 0.031
regulation of transferase activity GO:0051338 31 0.030
system process GO:0003008 136 0.030
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.030
cellular protein modification process GO:0006464 207 0.030
neurogenesis GO:0022008 236 0.030
regulation of cell cycle process GO:0010564 145 0.029
regulation of ras gtpase activity GO:0032318 21 0.029
nucleic acid templated transcription GO:0097659 169 0.029
defense response to bacterium GO:0042742 86 0.029
regulation of cell communication GO:0010646 176 0.029
nucleoside triphosphate metabolic process GO:0009141 87 0.029
anatomical structure formation involved in morphogenesis GO:0048646 250 0.029
nucleobase containing small molecule metabolic process GO:0055086 115 0.028
mitotic cell cycle process GO:1903047 194 0.028
organic substance transport GO:0071702 113 0.028
multicellular organismal reproductive behavior GO:0033057 384 0.028
cell fate commitment GO:0045165 139 0.028
positive regulation of phosphate metabolic process GO:0045937 56 0.027
heterocycle catabolic process GO:0046700 119 0.027
mitotic nuclear division GO:0007067 89 0.027
regulation of purine nucleotide catabolic process GO:0033121 35 0.027
regulation of neuromuscular synaptic transmission GO:1900073 1 0.027
genitalia development GO:0048806 741 0.027
single organism reproductive process GO:0044702 1196 0.027
positive regulation of phosphorus metabolic process GO:0010562 56 0.026
neuron development GO:0048666 199 0.026
positive regulation of catabolic process GO:0009896 38 0.026
rho protein signal transduction GO:0007266 2 0.026
cytokinesis GO:0000910 80 0.026
positive regulation of growth GO:0045927 369 0.026
regulation of developmental growth GO:0048638 389 0.025
cell surface receptor signaling pathway GO:0007166 149 0.025
myofibril assembly GO:0030239 154 0.025
response to wounding GO:0009611 4 0.025
positive regulation of biosynthetic process GO:0009891 109 0.024
protein metabolic process GO:0019538 422 0.024
regulation of protein metabolic process GO:0051246 81 0.024
regulation of cell cycle GO:0051726 194 0.024
meiotic nuclear division GO:0007126 300 0.024
long term memory GO:0007616 2 0.024
cell development GO:0048468 696 0.024
purine nucleotide metabolic process GO:0006163 95 0.024
negative regulation of ion transmembrane transporter activity GO:0032413 3 0.024
multicellular organism growth GO:0035264 385 0.024
response to external biotic stimulus GO:0043207 101 0.023
chromosome organization involved in meiosis GO:0070192 25 0.023
sensory organ morphogenesis GO:0090596 2 0.023
organelle assembly GO:0070925 214 0.022
regulation of cellular component movement GO:0051270 62 0.022
cellular macromolecule catabolic process GO:0044265 73 0.022
developmental growth GO:0048589 412 0.022
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.022
directional locomotion GO:0033058 14 0.021
nucleobase containing compound metabolic process GO:0006139 406 0.021
biological adhesion GO:0022610 21 0.021
negative regulation of cellular process GO:0048523 239 0.021
organonitrogen compound metabolic process GO:1901564 151 0.021
positive regulation of developmental growth GO:0048639 354 0.021
cellular response to organic substance GO:0071310 119 0.021
developmental process involved in reproduction GO:0003006 1165 0.020
negative regulation of macromolecule metabolic process GO:0010605 229 0.020
positive regulation of nucleic acid templated transcription GO:1903508 102 0.020
lipid metabolic process GO:0006629 77 0.020
ubiquitin dependent protein catabolic process GO:0006511 32 0.020
negative regulation of metabolic process GO:0009892 240 0.020
small gtpase mediated signal transduction GO:0007264 32 0.020
negative regulation of gene expression GO:0010629 217 0.020
signal transduction by phosphorylation GO:0023014 31 0.020
intracellular transport GO:0046907 77 0.020
striated muscle myosin thick filament assembly GO:0071688 138 0.020
regulation of gtp catabolic process GO:0033124 32 0.020
purine ribonucleoside catabolic process GO:0046130 75 0.019
ribonucleoside triphosphate metabolic process GO:0009199 87 0.019
nucleic acid metabolic process GO:0090304 299 0.019
transcription dna templated GO:0006351 168 0.019
striated muscle cell development GO:0055002 157 0.019
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.019
negative regulation of cellular component organization GO:0051129 33 0.019
regulation of cell differentiation GO:0045595 81 0.019
defense response GO:0006952 296 0.019
meiotic cell cycle GO:0051321 335 0.019
regulation of gtpase activity GO:0043087 30 0.019
regulation of growth GO:0040008 409 0.018
gonad development GO:0008406 840 0.018
epithelium development GO:0060429 68 0.018
defense response to other organism GO:0098542 100 0.018
defense response to gram negative bacterium GO:0050829 64 0.018
guanosine containing compound catabolic process GO:1901069 48 0.018
detection of external stimulus GO:0009581 4 0.018
ribose phosphate metabolic process GO:0019693 99 0.018
cellular protein catabolic process GO:0044257 37 0.018
myosin filament assembly GO:0031034 138 0.018
regulation of system process GO:0044057 27 0.018
positive regulation of cellular metabolic process GO:0031325 178 0.017
female gamete generation GO:0007292 254 0.017
gene expression GO:0010467 412 0.017
regulation of multicellular organismal development GO:2000026 317 0.017
ribonucleotide metabolic process GO:0009259 99 0.017
reproductive structure development GO:0048608 850 0.017
inductive cell migration GO:0040039 145 0.017
positive regulation of gtpase activity GO:0043547 28 0.017
regulation of signal transduction GO:0009966 135 0.017
nucleoside phosphate metabolic process GO:0006753 108 0.017
regulation of protein import into nucleus GO:0042306 3 0.017
synaptic transmission GO:0007268 106 0.017
regulation of nucleoside metabolic process GO:0009118 37 0.017
positive regulation of ras gtpase activity GO:0032320 19 0.017
positive regulation of cellular catabolic process GO:0031331 35 0.016
regulation of transport GO:0051049 91 0.016
regulation of nuclear division GO:0051783 115 0.016
muscle cell development GO:0055001 158 0.016
positive regulation of protein metabolic process GO:0051247 45 0.016
microtubule based process GO:0007017 182 0.016
positive regulation of nucleoside metabolic process GO:0045979 28 0.016
organelle localization GO:0051640 127 0.016
post embryonic organ development GO:0048569 336 0.016
regulation of protein kinase activity GO:0045859 28 0.016
purine nucleoside triphosphate metabolic process GO:0009144 87 0.016
response to bacterium GO:0009617 86 0.015
feeding behavior GO:0007631 70 0.015
memory GO:0007613 3 0.015
membrane organization GO:0061024 135 0.015
gtp metabolic process GO:0046039 46 0.015
response to other organism GO:0051707 101 0.015
purine nucleoside metabolic process GO:0042278 92 0.015
ribonucleotide catabolic process GO:0009261 75 0.015
carbohydrate derivative metabolic process GO:1901135 141 0.015
regulation of purine nucleotide metabolic process GO:1900542 37 0.015
peptidyl amino acid modification GO:0018193 58 0.015
regulation of phosphorylation GO:0042325 45 0.015
hermaphrodite genitalia development GO:0040035 734 0.015
excretion GO:0007588 49 0.014
regulation of nucleocytoplasmic transport GO:0046822 3 0.014
protein localization GO:0008104 205 0.014
negative regulation of response to stimulus GO:0048585 73 0.014
myosin filament organization GO:0031033 138 0.014
secretion by cell GO:0032940 138 0.014
muscle structure development GO:0061061 191 0.014
membrane depolarization GO:0051899 1 0.014
regulation of cell division GO:0051302 142 0.014
neuron projection development GO:0031175 187 0.014
intracellular signal transduction GO:0035556 96 0.013
regulation of behavior GO:0050795 97 0.013
cell morphogenesis GO:0000902 163 0.013
positive regulation of neurogenesis GO:0050769 4 0.013
purine nucleotide catabolic process GO:0006195 75 0.013
small molecule metabolic process GO:0044281 186 0.013
sex differentiation GO:0007548 909 0.013
nucleoside metabolic process GO:0009116 99 0.013
neuron projection morphogenesis GO:0048812 114 0.013
organonitrogen compound catabolic process GO:1901565 90 0.013
purine nucleoside triphosphate catabolic process GO:0009146 72 0.013
molting cycle GO:0042303 281 0.013
ion transmembrane transport GO:0034220 91 0.013
endodermal cell differentiation GO:0035987 18 0.013
cell projection morphogenesis GO:0048858 148 0.013
proteasomal protein catabolic process GO:0010498 20 0.013
meiotic cell cycle process GO:1903046 170 0.013
hormone transport GO:0009914 2 0.013
epithelial tube morphogenesis GO:0060562 1 0.012
regulation of cellular ketone metabolic process GO:0010565 3 0.012
synaptic growth at neuromuscular junction GO:0051124 1 0.012
regulation of cation channel activity GO:2001257 3 0.012
innate immune response GO:0045087 190 0.012
transmembrane transport GO:0055085 110 0.012
cell morphogenesis involved in differentiation GO:0000904 112 0.012
neuromuscular junction development GO:0007528 2 0.012
dorsal ventral axon guidance GO:0033563 19 0.012
regulation of post embryonic development GO:0048580 260 0.012
spindle checkpoint GO:0031577 4 0.012
collagen and cuticulin based cuticle development GO:0040002 99 0.012
rna metabolic process GO:0016070 228 0.011
purine containing compound catabolic process GO:0072523 75 0.011
tissue morphogenesis GO:0048729 65 0.011
regulation of epithelial cell proliferation GO:0050678 1 0.011
positive regulation of metabolic process GO:0009893 187 0.011
regulation of cellular amino acid metabolic process GO:0006521 0 0.011
regulation of kinase activity GO:0043549 29 0.011
nucleoside catabolic process GO:0009164 78 0.011
peptidyl tyrosine phosphorylation GO:0018108 2 0.011
amine metabolic process GO:0009308 15 0.011
gtp catabolic process GO:0006184 46 0.011
regulation of cell development GO:0060284 49 0.011
negative regulation of signaling GO:0023057 61 0.011
positive regulation of molecular function GO:0044093 61 0.011
macromolecule biosynthetic process GO:0009059 250 0.010
secretion GO:0046903 147 0.010
pharyngeal pumping GO:0043050 58 0.010
protein modification process GO:0036211 207 0.010
cell projection organization GO:0030030 231 0.010
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.010
heterocycle biosynthetic process GO:0018130 187 0.010
regulation of cytoskeleton organization GO:0051493 41 0.010
negative regulation of response to dna damage stimulus GO:2001021 2 0.010
tube development GO:0035295 126 0.010
positive regulation of cell death GO:0010942 38 0.010
regulation of cytoplasmic transport GO:1903649 3 0.010
nucleoside phosphate catabolic process GO:1901292 77 0.010
regulation of nucleotide catabolic process GO:0030811 35 0.010

ape-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.040