Caenorhabditis elegans

60 known processes

pab-1 (CELE_Y106G6H.2)

Protein PAB-1

pab-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development ending in birth or egg hatching GO:0009792 2992 0.988
embryo development GO:0009790 3052 0.968
post embryonic development GO:0009791 2152 0.881
multicellular organismal reproductive process GO:0048609 815 0.650
gamete generation GO:0007276 461 0.524
sexual reproduction GO:0019953 546 0.497
establishment of localization GO:0051234 1171 0.455
mitotic spindle organization GO:0007052 81 0.423
organ development GO:0048513 1102 0.423
multicellular organism reproduction GO:0032504 819 0.393
reproductive system development GO:0061458 850 0.381
apoptotic process GO:0006915 478 0.378
cell death GO:0008219 547 0.373
reproductive structure development GO:0048608 850 0.350
ribosome biogenesis GO:0042254 4 0.309
cell cycle process GO:0022402 482 0.296
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.292
nucleotide metabolic process GO:0009117 108 0.279
developmental process involved in reproduction GO:0003006 1165 0.274
cell cycle GO:0007049 526 0.271
germ cell development GO:0007281 351 0.263
meiotic nuclear division GO:0007126 300 0.261
locomotion GO:0040011 1634 0.260
single organism reproductive process GO:0044702 1196 0.250
protein metabolic process GO:0019538 422 0.247
Yeast
sex differentiation GO:0007548 909 0.240
regulation of meiotic cell cycle GO:0051445 136 0.235
mitotic cell cycle process GO:1903047 194 0.234
endocytosis GO:0006897 819 0.223
biosynthetic process GO:0009058 323 0.223
Yeast
development of primary sexual characteristics GO:0045137 840 0.222
microtubule based process GO:0007017 182 0.210
oogenesis GO:0048477 229 0.210
regulation of cell cycle process GO:0010564 145 0.203
organelle organization GO:0006996 783 0.202
gene expression GO:0010467 412 0.176
Yeast Mouse
axon guidance GO:0007411 82 0.151
cellular biosynthetic process GO:0044249 315 0.150
Yeast
programmed cell death GO:0012501 500 0.150
cytoskeleton organization GO:0007010 339 0.149
female gamete generation GO:0007292 254 0.147
purine ribonucleotide metabolic process GO:0009150 95 0.146
macromolecule biosynthetic process GO:0009059 250 0.146
Yeast
negative regulation of biological process GO:0048519 567 0.141
Human Yeast Mouse
regulation of metabolic process GO:0019222 478 0.140
Human Yeast Mouse
nucleoside phosphate metabolic process GO:0006753 108 0.134
death GO:0016265 547 0.133
vesicle mediated transport GO:0016192 852 0.130
hermaphrodite genitalia development GO:0040035 734 0.129
single organism organelle organization GO:1902589 501 0.126
macromolecule localization GO:0033036 771 0.123
regulation of cell cycle GO:0051726 194 0.115
meiotic cell cycle GO:0051321 335 0.110
gonad development GO:0008406 840 0.110
purine ribonucleoside metabolic process GO:0046128 92 0.105
establishment of localization in cell GO:0051649 318 0.104
nucleobase containing compound metabolic process GO:0006139 406 0.104
transport GO:0006810 1093 0.103
aging GO:0007568 812 0.103
glycosyl compound metabolic process GO:1901657 100 0.098
oviposition GO:0018991 364 0.094
spindle organization GO:0007051 92 0.091
organic substance biosynthetic process GO:1901576 323 0.091
Yeast
cellular macromolecule biosynthetic process GO:0034645 247 0.089
Yeast
regulation of nitrogen compound metabolic process GO:0051171 222 0.089
Human Yeast Mouse
response to chemical GO:0042221 356 0.088
organonitrogen compound metabolic process GO:1901564 151 0.088
organelle fission GO:0048285 363 0.085
negative regulation of cellular process GO:0048523 239 0.085
Human
multicellular organismal reproductive behavior GO:0033057 384 0.084
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.081
regulation of biological quality GO:0065008 741 0.080
negative regulation of gene expression GO:0010629 217 0.080
Mouse
rna localization GO:0006403 3 0.080
rrna metabolic process GO:0016072 3 0.079
single organism localization GO:1902578 518 0.078
single organism catabolic process GO:0044712 129 0.077
ribose phosphate metabolic process GO:0019693 99 0.076
cell development GO:0048468 696 0.074
maintenance of location GO:0051235 580 0.074
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.073
rna metabolic process GO:0016070 228 0.073
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.072
Yeast
pole plasm assembly GO:0007315 2 0.071
molting cycle GO:0042303 281 0.071
ribonucleoprotein complex assembly GO:0022618 4 0.070
positive regulation of cellular process GO:0048522 332 0.069
Mouse
nucleoside metabolic process GO:0009116 99 0.067
regulation of multicellular organismal process GO:0051239 726 0.065
genitalia development GO:0048806 741 0.065
lipid storage GO:0019915 565 0.065
small molecule metabolic process GO:0044281 186 0.065
regulation of biosynthetic process GO:0009889 189 0.065
Yeast
meiotic cell cycle process GO:1903046 170 0.064
nucleoside triphosphate catabolic process GO:0009143 72 0.064
carbohydrate derivative metabolic process GO:1901135 141 0.063
lipid localization GO:0010876 573 0.062
oocyte axis specification GO:0007309 2 0.061
macromolecular complex subunit organization GO:0043933 320 0.059
ribonucleoside metabolic process GO:0009119 98 0.059
protein catabolic process GO:0030163 162 0.059
nucleobase containing small molecule metabolic process GO:0055086 115 0.059
developmental growth GO:0048589 412 0.059
purine containing compound catabolic process GO:0072523 75 0.058
single organism transport GO:0044765 447 0.058
cellular component movement GO:0006928 388 0.056
nucleoside phosphate catabolic process GO:1901292 77 0.054
receptor mediated endocytosis GO:0006898 715 0.054
cellular protein metabolic process GO:0044267 279 0.054
Yeast
response to external stimulus GO:0009605 289 0.053
chemotaxis GO:0006935 120 0.053
cell motility GO:0048870 313 0.053
purine ribonucleoside catabolic process GO:0046130 75 0.052
behavior GO:0007610 527 0.052
regulation of macromolecule biosynthetic process GO:0010556 189 0.051
Yeast
organic substance catabolic process GO:1901575 294 0.051
Human Yeast Mouse
purine containing compound metabolic process GO:0072521 95 0.051
regulation of growth GO:0040008 409 0.050
phosphorylation GO:0016310 116 0.049
positive regulation of developmental growth GO:0048639 354 0.048
positive regulation of multicellular organismal process GO:0051240 417 0.048
macromolecule catabolic process GO:0009057 202 0.047
Human Yeast Mouse
cellular response to chemical stimulus GO:0070887 129 0.047
multicellular organismal aging GO:0010259 812 0.047
organophosphate metabolic process GO:0019637 125 0.047
positive regulation of growth GO:0045927 369 0.047
regulation of cellular biosynthetic process GO:0031326 189 0.045
Yeast
aromatic compound catabolic process GO:0019439 116 0.045
Human Yeast Mouse
growth GO:0040007 562 0.044
multicellular organism growth GO:0035264 385 0.044
macromolecular complex assembly GO:0065003 193 0.044
positive regulation of developmental process GO:0051094 408 0.044
regulation of developmental process GO:0050793 684 0.043
response to organic substance GO:0010033 131 0.043
multi organism reproductive process GO:0044703 867 0.042
purine nucleoside metabolic process GO:0042278 92 0.042
regulation of multicellular organism growth GO:0040014 373 0.042
regulation of cell division GO:0051302 142 0.042
regulation of vulval development GO:0040028 248 0.042
negative regulation of metabolic process GO:0009892 240 0.041
Human Yeast Mouse
posttranscriptional regulation of gene expression GO:0010608 166 0.040
Yeast
ribonucleoside triphosphate metabolic process GO:0009199 87 0.040
ribonucleoside monophosphate metabolic process GO:0009161 45 0.040
negative regulation of nematode larval development GO:0061064 208 0.039
reproductive behavior GO:0019098 387 0.039
localization of cell GO:0051674 313 0.038
regulation of mitotic cell cycle GO:0007346 76 0.038
rrna processing GO:0006364 3 0.038
response to other organism GO:0051707 101 0.037
regulation of meiosis GO:0040020 94 0.037
determination of adult lifespan GO:0008340 812 0.037
establishment of protein localization to membrane GO:0090150 3 0.036
dna metabolic process GO:0006259 74 0.036
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.036
Human Yeast Mouse
taxis GO:0042330 128 0.035
regulation of gene expression GO:0010468 366 0.035
Yeast Mouse
inductive cell migration GO:0040039 145 0.035
nucleoside catabolic process GO:0009164 78 0.034
mitotic nuclear division GO:0007067 89 0.034
regulation of cellular metabolic process GO:0031323 305 0.034
Human Yeast Mouse
regulation of developmental growth GO:0048638 389 0.034
cellular component assembly GO:0022607 293 0.033
regulation of localization GO:0032879 194 0.033
cellular response to stress GO:0033554 162 0.033
multi organism behavior GO:0051705 389 0.033
multi multicellular organism process GO:0044706 390 0.033
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.032
Human
nucleotide catabolic process GO:0009166 77 0.032
purine nucleoside catabolic process GO:0006152 75 0.031
purine nucleoside monophosphate biosynthetic process GO:0009127 4 0.031
body morphogenesis GO:0010171 620 0.031
cellular component biogenesis GO:0044085 297 0.031
regulation of gastrulation GO:0010470 4 0.031
cellular response to topologically incorrect protein GO:0035967 76 0.031
regulation of translation GO:0006417 19 0.030
Yeast
protein complex subunit organization GO:0071822 280 0.030
regulation of macromolecule metabolic process GO:0060255 421 0.030
Human Yeast Mouse
ribonucleotide metabolic process GO:0009259 99 0.030
organic cyclic compound catabolic process GO:1901361 119 0.030
Human Yeast Mouse
positive regulation of multicellular organism growth GO:0040018 352 0.030
translation GO:0006412 37 0.030
Yeast
vulval development GO:0040025 333 0.029
oocyte construction GO:0007308 2 0.029
cellular response to organic substance GO:0071310 119 0.029
establishment of rna localization GO:0051236 3 0.029
catabolic process GO:0009056 318 0.029
Human Yeast Mouse
negative regulation of developmental process GO:0051093 227 0.029
purine nucleoside triphosphate catabolic process GO:0009146 72 0.029
negative regulation of vulval development GO:0040027 206 0.029
organophosphate catabolic process GO:0046434 81 0.029
proteolysis involved in cellular protein catabolic process GO:0051603 32 0.028
cell migration GO:0016477 306 0.028
protein transmembrane transport GO:0071806 4 0.027
negative regulation of macromolecule metabolic process GO:0010605 229 0.027
Human Mouse
regulation of primary metabolic process GO:0080090 292 0.027
Human Yeast Mouse
nucleoside monophosphate metabolic process GO:0009123 46 0.027
purine nucleotide metabolic process GO:0006163 95 0.027
phosphorus metabolic process GO:0006793 232 0.026
meiotic chromosome segregation GO:0045132 139 0.026
innate immune response GO:0045087 190 0.026
purine nucleoside triphosphate metabolic process GO:0009144 87 0.026
neuron differentiation GO:0030182 217 0.026
carbohydrate derivative catabolic process GO:1901136 82 0.025
nucleoside triphosphate metabolic process GO:0009141 87 0.025
negative regulation of biosynthetic process GO:0009890 65 0.025
cellular component morphogenesis GO:0032989 318 0.024
centrosomal and pronuclear rotation GO:0035047 6 0.024
cell projection morphogenesis GO:0048858 148 0.023
regulation of cellular protein metabolic process GO:0032268 75 0.023
Yeast
ribonucleoside catabolic process GO:0042454 77 0.023
ribonucleoside triphosphate catabolic process GO:0009203 72 0.023
purine nucleoside monophosphate metabolic process GO:0009126 43 0.023
negative regulation of translation GO:0017148 10 0.023
guanosine containing compound catabolic process GO:1901069 48 0.022
dauer larval development GO:0040024 92 0.022
purine ribonucleotide catabolic process GO:0009154 75 0.022
glycosyl compound catabolic process GO:1901658 79 0.022
nervous system development GO:0007399 253 0.022
defense response GO:0006952 296 0.021
organonitrogen compound catabolic process GO:1901565 90 0.021
nucleic acid metabolic process GO:0090304 299 0.020
cellular catabolic process GO:0044248 199 0.020
Human Yeast Mouse
purine ribonucleoside monophosphate metabolic process GO:0009167 43 0.020
cell cycle switching mitotic to meiotic cell cycle GO:0051728 35 0.019
negative regulation of response to stimulus GO:0048585 73 0.019
phagocytosis GO:0006909 115 0.019
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.019
post embryonic organ development GO:0048569 336 0.019
regulation of apoptotic signaling pathway GO:2001233 1 0.019
aromatic compound biosynthetic process GO:0019438 192 0.018
single organism biosynthetic process GO:0044711 91 0.018
regulation of cell communication GO:0010646 176 0.018
cellular macromolecular complex assembly GO:0034622 184 0.018
cellular localization GO:0051641 360 0.017
heterocycle catabolic process GO:0046700 119 0.017
Human Yeast Mouse
regulation of post embryonic development GO:0048580 260 0.017
regulation of cellular component organization GO:0051128 248 0.017
nucleobase containing compound catabolic process GO:0034655 114 0.016
Human Yeast Mouse
male gamete generation GO:0048232 41 0.016
response to external biotic stimulus GO:0043207 101 0.016
signaling GO:0023052 401 0.016
negative regulation of post embryonic development GO:0048581 208 0.016
negative regulation of cellular protein metabolic process GO:0032269 27 0.016
regulation of nuclear division GO:0051783 115 0.016
gene silencing by rna GO:0031047 143 0.016
Mouse
modification dependent macromolecule catabolic process GO:0043632 32 0.016
microtubule polymerization or depolymerization GO:0031109 22 0.016
fertilization GO:0009566 63 0.016
negative regulation of cell cycle GO:0045786 53 0.016
spermatogenesis GO:0007283 41 0.016
phosphate containing compound metabolic process GO:0006796 232 0.016
immune response GO:0006955 192 0.015
atp metabolic process GO:0046034 42 0.015
rna interference GO:0016246 137 0.015
tube morphogenesis GO:0035239 79 0.015
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.015
gtp catabolic process GO:0006184 46 0.015
neuron projection guidance GO:0097485 82 0.015
negative regulation of multicellular organismal process GO:0051241 236 0.015
translational initiation GO:0006413 2 0.015
Yeast
neuron projection development GO:0031175 187 0.015
adult behavior GO:0030534 3 0.014
apical junction assembly GO:0043297 1 0.014
cell division GO:0051301 262 0.014
cell recognition GO:0008037 85 0.014
negative regulation of signaling GO:0023057 61 0.014
multi organism reproductive behavior GO:0044705 387 0.013
protein complex biogenesis GO:0070271 186 0.013
negative regulation of mitotic cell cycle GO:0045930 42 0.013
nucleic acid transport GO:0050657 3 0.013
heterocycle biosynthetic process GO:0018130 187 0.013
negative regulation of cell communication GO:0010648 61 0.013
intracellular transport GO:0046907 77 0.013
organelle assembly GO:0070925 214 0.013
establishment of mitotic spindle localization GO:0040001 41 0.013
regulation of apoptotic process GO:0042981 36 0.013
rna biosynthetic process GO:0032774 169 0.013
intracellular protein transmembrane transport GO:0065002 4 0.012
single organism intracellular transport GO:1902582 70 0.012
posttranscriptional gene silencing by rna GO:0035194 143 0.012
axon development GO:0061564 163 0.012
neuron projection morphogenesis GO:0048812 114 0.012
muscle structure development GO:0061061 191 0.012
regulation of response to stimulus GO:0048583 243 0.012
head development GO:0060322 1 0.012
negative regulation of cellular metabolic process GO:0031324 95 0.012
Human
anatomical structure formation involved in morphogenesis GO:0048646 250 0.012
neuron development GO:0048666 199 0.012
chromatin assembly or disassembly GO:0006333 1 0.012
chromosome organization involved in meiosis GO:0070192 25 0.012
meiosis i GO:0007127 19 0.012
nitrogen compound transport GO:0071705 49 0.012
epithelial tube morphogenesis GO:0060562 1 0.012
neurotransmitter transport GO:0006836 32 0.012
positive regulation of meiotic cell cycle GO:0051446 47 0.012
cellular response to abiotic stimulus GO:0071214 4 0.011
skeletal muscle organ development GO:0060538 3 0.011
meiotic cytokinesis GO:0033206 15 0.011
neurogenesis GO:0022008 236 0.011
oxoacid metabolic process GO:0043436 47 0.011
response to abiotic stimulus GO:0009628 152 0.011
tissue development GO:0009888 112 0.011
regulation of gene silencing GO:0060968 3 0.011
regulation of protein stability GO:0031647 3 0.011
organic acid metabolic process GO:0006082 47 0.011
cellular macromolecule catabolic process GO:0044265 73 0.011
Human Yeast Mouse
macromolecule modification GO:0043412 218 0.011
regulation of multicellular organismal development GO:2000026 317 0.011
regulation of organelle organization GO:0033043 164 0.011
ribonucleotide catabolic process GO:0009261 75 0.010
cell part morphogenesis GO:0032990 152 0.010
cellular amino acid metabolic process GO:0006520 15 0.010
endoplasmic reticulum unfolded protein response GO:0030968 66 0.010
germline cell cycle switching mitotic to meiotic cell cycle GO:0051729 35 0.010
germ line sex determination GO:0018992 51 0.010
actin filament based process GO:0030029 191 0.010
rna transport GO:0050658 3 0.010
purine nucleotide catabolic process GO:0006195 75 0.010
oocyte development GO:0048599 44 0.010
cellular response to unfolded protein GO:0034620 71 0.010
guanosine containing compound metabolic process GO:1901068 49 0.010
regulation of neurotransmitter levels GO:0001505 36 0.010
carbohydrate biosynthetic process GO:0016051 4 0.010

pab-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
congenital hypoplastic anemia DOID:1342 0 0.037
immune system disease DOID:2914 0 0.037
diamond blackfan anemia DOID:1339 0 0.037
aplastic anemia DOID:12449 0 0.037
disease of anatomical entity DOID:7 0 0.037
bone marrow disease DOID:4961 0 0.037
anemia DOID:2355 0 0.037
hematopoietic system disease DOID:74 0 0.037
disease of metabolism DOID:0014667 0 0.012
inherited metabolic disorder DOID:655 0 0.012