Caenorhabditis elegans

24 known processes

unc-68 (CELE_K11C4.5)

Protein UNC-68

unc-68 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development ending in birth or egg hatching GO:0009792 2992 0.862
embryo development GO:0009790 3052 0.606
Mouse
endocytosis GO:0006897 819 0.557
single organism organelle organization GO:1902589 501 0.542
skeletal muscle organ development GO:0060538 3 0.536
Mouse
regulation of developmental process GO:0050793 684 0.472
Fly
protein complex subunit organization GO:0071822 280 0.465
vesicle mediated transport GO:0016192 852 0.437
post embryonic development GO:0009791 2152 0.421
cell death GO:0008219 547 0.380
growth GO:0040007 562 0.361
organelle organization GO:0006996 783 0.360
organ development GO:0048513 1102 0.343
Mouse
regulation of growth GO:0040008 409 0.332
cell substrate adhesion GO:0031589 1 0.287
single organism reproductive process GO:0044702 1196 0.280
axonal defasciculation GO:0007414 1 0.279
cellular component biogenesis GO:0044085 297 0.271
organelle assembly GO:0070925 214 0.262
positive regulation of multicellular organismal process GO:0051240 417 0.258
Mouse
multicellular organismal reproductive process GO:0048609 815 0.256
sarcomere organization GO:0045214 10 0.251
positive regulation of locomotion GO:0040017 42 0.238
cell cycle process GO:0022402 482 0.237
protein complex biogenesis GO:0070271 186 0.230
membrane organization GO:0061024 135 0.227
regulation of developmental growth GO:0048638 389 0.225
determination of adult lifespan GO:0008340 812 0.222
macromolecular complex subunit organization GO:0043933 320 0.215
muscle tissue development GO:0060537 1 0.213
Mouse
regulation of multicellular organismal process GO:0051239 726 0.212
Mouse Fly
developmental growth GO:0048589 412 0.207
transport GO:0006810 1093 0.205
Zebrafish Mouse
organic substance catabolic process GO:1901575 294 0.201
developmental process involved in reproduction GO:0003006 1165 0.190
regulation of synapse assembly GO:0051963 2 0.185
integrin mediated signaling pathway GO:0007229 1 0.184
death GO:0016265 547 0.183
post embryonic organ development GO:0048569 336 0.180
synaptic vesicle endocytosis GO:0048488 3 0.179
multicellular organism reproduction GO:0032504 819 0.174
cell cycle GO:0007049 526 0.169
signaling GO:0023052 401 0.167
Mouse
cellular component movement GO:0006928 388 0.166
locomotion GO:0040011 1634 0.166
cellular component assembly involved in morphogenesis GO:0010927 183 0.165
body morphogenesis GO:0010171 620 0.158
ion transport GO:0006811 113 0.157
Zebrafish Mouse
cell projection assembly GO:0030031 35 0.157
positive regulation of developmental process GO:0051094 408 0.155
cilium organization GO:0044782 32 0.154
multicellular organism growth GO:0035264 385 0.154
cellular component assembly GO:0022607 293 0.149
sex differentiation GO:0007548 909 0.147
regulation of multicellular organismal development GO:2000026 317 0.145
muscle organ development GO:0007517 26 0.142
Mouse
sexual reproduction GO:0019953 546 0.137
positive regulation of developmental growth GO:0048639 354 0.137
establishment of localization GO:0051234 1171 0.134
Zebrafish Mouse
receptor mediated endocytosis GO:0006898 715 0.129
programmed cell death GO:0012501 500 0.129
response to external stimulus GO:0009605 289 0.129
cytoskeleton organization GO:0007010 339 0.128
regulation of vulval development GO:0040028 248 0.128
cell projection organization GO:0030030 231 0.126
gamete generation GO:0007276 461 0.124
defense response GO:0006952 296 0.120
female gamete generation GO:0007292 254 0.120
cell development GO:0048468 696 0.119
Mouse
single organism signaling GO:0044700 401 0.119
Mouse
positive regulation of multicellular organism growth GO:0040018 352 0.117
aging GO:0007568 812 0.116
actomyosin structure organization GO:0031032 154 0.116
regulation of post embryonic development GO:0048580 260 0.114
gonad development GO:0008406 840 0.114
macromolecule catabolic process GO:0009057 202 0.114
response to abiotic stimulus GO:0009628 152 0.111
Mouse
macromolecular complex assembly GO:0065003 193 0.110
myofibril assembly GO:0030239 154 0.110
muscle cell development GO:0055001 158 0.110
Mouse
regulation of locomotion GO:0040012 161 0.108
anatomical structure formation involved in morphogenesis GO:0048646 250 0.103
multicellular organismal aging GO:0010259 812 0.103
regulation of multicellular organism growth GO:0040014 373 0.102
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.099
response to wounding GO:0009611 4 0.099
striated muscle cell differentiation GO:0051146 158 0.099
Mouse
head development GO:0060322 1 0.097
defense response to other organism GO:0098542 100 0.097
cellular macromolecular complex assembly GO:0034622 184 0.097
apoptotic process GO:0006915 478 0.096
Mouse
regulation of nematode larval development GO:0061062 260 0.096
multi organism behavior GO:0051705 389 0.094
regulation of biological quality GO:0065008 741 0.094
Mouse
muscle attachment GO:0016203 3 0.092
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.092
regulation of filopodium assembly GO:0051489 2 0.092
muscle structure development GO:0061061 191 0.092
Mouse
protein metabolic process GO:0019538 422 0.091
organonitrogen compound metabolic process GO:1901564 151 0.090
striated muscle cell development GO:0055002 157 0.086
Mouse
oviposition GO:0018991 364 0.084
cell part morphogenesis GO:0032990 152 0.081
catabolic process GO:0009056 318 0.080
organelle fission GO:0048285 363 0.080
multi organism reproductive process GO:0044703 867 0.078
cellular component morphogenesis GO:0032989 318 0.077
divalent metal ion transport GO:0070838 17 0.077
Zebrafish Mouse
cellular localization GO:0051641 360 0.076
muscle system process GO:0003012 43 0.076
Zebrafish Mouse Fly
actin cytoskeleton organization GO:0030036 184 0.076
single organism transport GO:0044765 447 0.075
Zebrafish Mouse
macromolecule localization GO:0033036 771 0.075
response to external biotic stimulus GO:0043207 101 0.075
positive regulation of growth GO:0045927 369 0.075
meiotic cell cycle GO:0051321 335 0.075
negative regulation of nematode larval development GO:0061064 208 0.073
neurological system process GO:0050877 53 0.073
protein localization to basolateral plasma membrane GO:1903361 7 0.072
cell projection morphogenesis GO:0048858 148 0.071
localization of cell GO:0051674 313 0.070
reproductive structure development GO:0048608 850 0.069
negative regulation of biological process GO:0048519 567 0.069
Mouse
genitalia development GO:0048806 741 0.065
negative regulation of post embryonic development GO:0048581 208 0.065
reproductive behavior GO:0019098 387 0.064
regulation of rna biosynthetic process GO:2001141 165 0.062
Mouse
actin filament based process GO:0030029 191 0.062
reproductive system development GO:0061458 850 0.062
regulation of actin filament based process GO:0032970 22 0.062
Mouse
regulation of nucleoside metabolic process GO:0009118 37 0.060
behavior GO:0007610 527 0.059
Zebrafish
cell matrix adhesion GO:0007160 1 0.058
inductive cell migration GO:0040039 145 0.057
organic substance transport GO:0071702 113 0.056
cellular protein complex assembly GO:0043623 178 0.056
response to biotic stimulus GO:0009607 101 0.055
response to chemical GO:0042221 356 0.055
Zebrafish Mouse Fly
regulation of cell projection assembly GO:0060491 3 0.055
cellular response to organic substance GO:0071310 119 0.055
Mouse
organ morphogenesis GO:0009887 67 0.053
Mouse
axon guidance GO:0007411 82 0.053
defense response to bacterium GO:0042742 86 0.053
regulation of cellular metabolic process GO:0031323 305 0.052
Mouse
response to other organism GO:0051707 101 0.052
cellular biosynthetic process GO:0044249 315 0.052
Mouse
multicellular organismal reproductive behavior GO:0033057 384 0.051
regulation of cellular component organization GO:0051128 248 0.051
hermaphrodite genitalia development GO:0040035 734 0.049
meiotic nuclear division GO:0007126 300 0.048
lipid localization GO:0010876 573 0.048
cation transport GO:0006812 78 0.046
Zebrafish Mouse
maintenance of location GO:0051235 580 0.045
Mouse
negative regulation of vulval development GO:0040027 206 0.045
regulation of gene expression epigenetic GO:0040029 163 0.045
rna localization GO:0006403 3 0.044
regulation of nitrogen compound metabolic process GO:0051171 222 0.044
Mouse
cellular catabolic process GO:0044248 199 0.041
response to endogenous stimulus GO:0009719 33 0.041
Mouse
positive regulation of cellular process GO:0048522 332 0.040
protein complex assembly GO:0006461 186 0.040
embryonic body morphogenesis GO:0010172 49 0.039
lipid storage GO:0019915 565 0.039
immune response GO:0006955 192 0.039
regulation of cell cell adhesion GO:0022407 1 0.038
microtubule based process GO:0007017 182 0.038
apoptotic cell clearance GO:0043277 111 0.037
muscle cell differentiation GO:0042692 171 0.037
Mouse
development of primary sexual characteristics GO:0045137 840 0.037
positive regulation of molecular function GO:0044093 61 0.036
Mouse
molting cycle GO:0042303 281 0.036
carbohydrate derivative metabolic process GO:1901135 141 0.036
establishment of localization in cell GO:0051649 318 0.036
Mouse
negative regulation of cellular process GO:0048523 239 0.035
Mouse
mesodermal cell migration GO:0008078 9 0.035
fertilization GO:0009566 63 0.035
nucleobase containing compound metabolic process GO:0006139 406 0.035
Mouse
germ cell development GO:0007281 351 0.035
regulation of cellular component biogenesis GO:0044087 26 0.035
ribonucleoside metabolic process GO:0009119 98 0.034
neurogenesis GO:0022008 236 0.034
cilium assembly GO:0042384 28 0.034
single organism localization GO:1902578 518 0.034
Zebrafish Mouse
regulation of cytoskeleton organization GO:0051493 41 0.034
actin filament organization GO:0007015 21 0.034
myosin filament assembly GO:0031034 138 0.033
small molecule metabolic process GO:0044281 186 0.032
cell morphogenesis involved in differentiation GO:0000904 112 0.032
purine ribonucleotide metabolic process GO:0009150 95 0.032
negative regulation of developmental process GO:0051093 227 0.031
positive regulation of catalytic activity GO:0043085 59 0.031
regulation of lamellipodium organization GO:1902743 1 0.031
aromatic compound catabolic process GO:0019439 116 0.030
cell migration GO:0016477 306 0.030
synapse organization GO:0050808 24 0.030
regulation of anatomical structure size GO:0090066 46 0.030
lamellipodium assembly GO:0030032 2 0.030
regulation of organelle organization GO:0033043 164 0.029
cellular protein metabolic process GO:0044267 279 0.029
cellular response to chemical stimulus GO:0070887 129 0.029
Zebrafish Mouse
filopodium assembly GO:0046847 2 0.029
protein catabolic process GO:0030163 162 0.029
dorsal ventral axon guidance GO:0033563 19 0.029
regulation of response to stimulus GO:0048583 243 0.029
regulation of nervous system development GO:0051960 41 0.028
memory GO:0007613 3 0.028
ribonucleoside triphosphate metabolic process GO:0009199 87 0.028
regulation of cell projection organization GO:0031344 38 0.028
organelle localization GO:0051640 127 0.028
digestive system development GO:0055123 122 0.028
establishment of organelle localization GO:0051656 123 0.027
synaptic vesicle recycling GO:0036465 3 0.026
macromolecule biosynthetic process GO:0009059 250 0.026
Mouse
striated muscle myosin thick filament assembly GO:0071688 138 0.026
nucleobase containing small molecule metabolic process GO:0055086 115 0.026
motor neuron axon guidance GO:0008045 13 0.026
heterocycle catabolic process GO:0046700 119 0.026
protein localization GO:0008104 205 0.025
neuron development GO:0048666 199 0.025
cell type specific apoptotic process GO:0097285 4 0.025
Mouse
regulation of signal transduction GO:0009966 135 0.024
neuron projection guidance GO:0097485 82 0.024
organophosphate metabolic process GO:0019637 125 0.024
establishment of protein localization to membrane GO:0090150 3 0.024
nucleotide metabolic process GO:0009117 108 0.024
actin filament based movement GO:0030048 4 0.024
positive regulation of cell migration GO:0030335 3 0.023
regulation of multi organism process GO:0043900 69 0.023
positive regulation of nucleotide catabolic process GO:0030813 28 0.023
ribonucleotide catabolic process GO:0009261 75 0.023
actin filament bundle assembly GO:0051017 3 0.023
cell surface receptor signaling pathway GO:0007166 149 0.023
Mouse
regulation of molecular function GO:0065009 89 0.023
Mouse
protein polymerization GO:0051258 26 0.022
biosynthetic process GO:0009058 323 0.022
Mouse
protein modification process GO:0036211 207 0.022
regulation of phagocytosis engulfment GO:0060099 17 0.022
skeletal muscle thin filament assembly GO:0030240 3 0.022
posttranscriptional gene silencing GO:0016441 143 0.021
cell division GO:0051301 262 0.021
neuromuscular junction development GO:0007528 2 0.021
organic substance biosynthetic process GO:1901576 323 0.021
Mouse
generation of neurons GO:0048699 235 0.021
mitotic cell cycle process GO:1903047 194 0.021
epithelial tube morphogenesis GO:0060562 1 0.021
Mouse
myosin filament organization GO:0031033 138 0.021
cell motility GO:0048870 313 0.020
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.020
regulation of cell proliferation GO:0042127 105 0.020
Fly
meiotic cell cycle process GO:1903046 170 0.020
synaptic growth at neuromuscular junction GO:0051124 1 0.020
regulation of cell morphogenesis GO:0022604 40 0.020
anatomical structure homeostasis GO:0060249 11 0.020
regulation of purine nucleotide metabolic process GO:1900542 37 0.020
endomembrane system organization GO:0010256 22 0.020
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.020
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.020
response to organic substance GO:0010033 131 0.019
Mouse
male sex differentiation GO:0046661 86 0.019
regulation of hydrolase activity GO:0051336 45 0.019
intracellular transport GO:0046907 77 0.019
Mouse
plasma membrane organization GO:0007009 9 0.019
phagocytosis engulfment GO:0006911 98 0.019
ribonucleotide metabolic process GO:0009259 99 0.019
protein oligomerization GO:0051259 4 0.019
membrane invagination GO:0010324 98 0.018
regulation of vesicle mediated transport GO:0060627 27 0.018
single organism membrane organization GO:0044802 35 0.018
digestive tract morphogenesis GO:0048546 76 0.018
nitrogen compound transport GO:0071705 49 0.018
ribose phosphate metabolic process GO:0019693 99 0.018
cell recognition GO:0008037 85 0.018
response to heat GO:0009408 50 0.017
purine nucleoside catabolic process GO:0006152 75 0.017
single organism catabolic process GO:0044712 129 0.017
system process GO:0003008 136 0.017
Zebrafish Mouse Fly
engulfment of apoptotic cell GO:0043652 94 0.017
tube development GO:0035295 126 0.017
Mouse
sensory organ morphogenesis GO:0090596 2 0.017
nucleoside phosphate catabolic process GO:1901292 77 0.017
cellular macromolecule biosynthetic process GO:0034645 247 0.017
Mouse
response to bacterium GO:0009617 86 0.017
cellular amine metabolic process GO:0044106 15 0.017
nucleic acid metabolic process GO:0090304 299 0.017
Mouse
positive regulation of hydrolase activity GO:0051345 38 0.017
amine metabolic process GO:0009308 15 0.017
negative regulation of cellular component organization GO:0051129 33 0.017
nucleoside phosphate metabolic process GO:0006753 108 0.017
homeostatic process GO:0042592 51 0.016
Mouse
organophosphate catabolic process GO:0046434 81 0.016
regulation of endocytosis GO:0030100 25 0.016
purine nucleotide metabolic process GO:0006163 95 0.016
oogenesis GO:0048477 229 0.016
ovulation GO:0030728 33 0.016
macromolecule modification GO:0043412 218 0.016
neuron projection morphogenesis GO:0048812 114 0.016
mitotic nuclear division GO:0007067 89 0.016
establishment of nucleus localization GO:0040023 55 0.016
regulation of macromolecule metabolic process GO:0060255 421 0.016
Mouse
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.016
regulation of nucleic acid templated transcription GO:1903506 165 0.015
Mouse
multi organism reproductive behavior GO:0044705 387 0.015
secretion by cell GO:0032940 138 0.015
glycosyl compound metabolic process GO:1901657 100 0.015
ion homeostasis GO:0050801 21 0.015
Mouse
neuron projection extension GO:1990138 37 0.015
cell adhesion GO:0007155 21 0.015
cellular nitrogen compound biosynthetic process GO:0044271 192 0.015
Mouse
transcription initiation from rna polymerase ii promoter GO:0006367 2 0.015
nucleoside metabolic process GO:0009116 99 0.015
regulation of nucleotide catabolic process GO:0030811 35 0.015
vulval development GO:0040025 333 0.015
nucleus localization GO:0051647 55 0.014
striated muscle contraction GO:0006941 17 0.014
Zebrafish Mouse
cellular nitrogen compound catabolic process GO:0044270 119 0.014
nucleoside triphosphate metabolic process GO:0009141 87 0.014
carboxylic acid metabolic process GO:0019752 34 0.014
nucleotide catabolic process GO:0009166 77 0.014
gene expression GO:0010467 412 0.014
Mouse
rna metabolic process GO:0016070 228 0.014
Mouse
neuron differentiation GO:0030182 217 0.014
purine nucleoside triphosphate metabolic process GO:0009144 87 0.014
purine ribonucleoside metabolic process GO:0046128 92 0.014
mesoderm development GO:0007498 27 0.014
eating behavior GO:0042755 59 0.014
taxis GO:0042330 128 0.014
spindle organization GO:0007051 92 0.014
organic cyclic compound catabolic process GO:1901361 119 0.014
nucleobase containing compound catabolic process GO:0034655 114 0.014
nucleoside catabolic process GO:0009164 78 0.014
g protein coupled receptor signaling pathway GO:0007186 46 0.014
Mouse
cellular response to nitrogen compound GO:1901699 24 0.014
Mouse
negative regulation of multicellular organismal process GO:0051241 236 0.014
negative regulation of developmental growth GO:0048640 10 0.013
ribonucleoside triphosphate catabolic process GO:0009203 72 0.013
regulation of cytoplasmic transport GO:1903649 3 0.013
Mouse
nervous system development GO:0007399 253 0.013
meiotic cytokinesis GO:0033206 15 0.013
regulation of atp catabolic process GO:1903289 3 0.013
regulation of response to wounding GO:1903034 1 0.013
microtubule based movement GO:0007018 33 0.013
defense response to fungus GO:0050832 19 0.013
regulation of cell cycle GO:0051726 194 0.013
tissue morphogenesis GO:0048729 65 0.013
Mouse
positive regulation of purine nucleotide catabolic process GO:0033123 28 0.013
regulation of gene expression GO:0010468 366 0.013
Mouse
oxoacid metabolic process GO:0043436 47 0.013
ion transmembrane transport GO:0034220 91 0.013
Zebrafish Mouse
regulation of cellular catabolic process GO:0031329 51 0.013
oocyte construction GO:0007308 2 0.012
pole plasm assembly GO:0007315 2 0.012
ribonucleoside catabolic process GO:0042454 77 0.012
calcium ion transport GO:0006816 16 0.012
Zebrafish Mouse
feeding behavior GO:0007631 70 0.012
sensory perception of smell GO:0007608 3 0.012
purine nucleoside monophosphate metabolic process GO:0009126 43 0.012
phagocytosis GO:0006909 115 0.012
cellular macromolecule localization GO:0070727 75 0.012
posttranscriptional gene silencing by rna GO:0035194 143 0.012
positive regulation of cysteine type endopeptidase activity GO:2001056 3 0.012
positive regulation of cellular metabolic process GO:0031325 178 0.012
enzyme linked receptor protein signaling pathway GO:0007167 50 0.012
Mouse
single organism behavior GO:0044708 83 0.012
Zebrafish
multi multicellular organism process GO:0044706 390 0.012
rna interference GO:0016246 137 0.012
regulation of cell death GO:0010941 65 0.012
apical junction assembly GO:0043297 1 0.012
positive regulation of catabolic process GO:0009896 38 0.012
embryonic morphogenesis GO:0048598 152 0.012
Mouse
regulation of oviposition GO:0046662 43 0.011
regulation of nucleotide metabolic process GO:0006140 37 0.011
cognition GO:0050890 27 0.011
tissue development GO:0009888 112 0.011
Mouse
regulation of cellular amino acid metabolic process GO:0006521 0 0.011
regulation of muscle contraction GO:0006937 20 0.011
Mouse
carbohydrate derivative catabolic process GO:1901136 82 0.011
peptidyl amino acid modification GO:0018193 58 0.011
phosphate containing compound metabolic process GO:0006796 232 0.011
guanosine containing compound catabolic process GO:1901069 48 0.011
tube morphogenesis GO:0035239 79 0.011
Mouse
cytoskeleton dependent cytokinesis GO:0061640 35 0.011
regulation of cellular amine metabolic process GO:0033238 0 0.011
endodermal cell differentiation GO:0035987 18 0.011
regulation of apoptotic signaling pathway GO:2001233 1 0.011
neuron projection development GO:0031175 187 0.011
purine ribonucleoside catabolic process GO:0046130 75 0.011
cell cell signaling GO:0007267 118 0.011
Mouse
actin filament bundle organization GO:0061572 3 0.010
organic acid metabolic process GO:0006082 47 0.010
neuromuscular process GO:0050905 1 0.010
metal ion transport GO:0030001 49 0.010
Zebrafish Mouse
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.010
Mouse
cuticle development GO:0042335 100 0.010
sensory perception GO:0007600 27 0.010
biological adhesion GO:0022610 21 0.010
regulation of catalytic activity GO:0050790 78 0.010
muscle contraction GO:0006936 43 0.010
Zebrafish Mouse Fly

unc-68 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.079
cardiovascular system disease DOID:1287 0 0.079
myopathy DOID:423 0 0.030
muscular disease DOID:0080000 0 0.030
heart disease DOID:114 0 0.030
cardiomyopathy DOID:0050700 0 0.030
musculoskeletal system disease DOID:17 0 0.030
muscle tissue disease DOID:66 0 0.030
nervous system disease DOID:863 0 0.010
disease of cellular proliferation DOID:14566 0 0.010