Caenorhabditis elegans

38 known processes

exp-2 (CELE_F12F3.1)

Protein EXP-2

exp-2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of nucleic acid templated transcription GO:1903508 102 0.208
post embryonic development GO:0009791 2152 0.203
transport GO:0006810 1093 0.175
behavior GO:0007610 527 0.172
Worm
embryo development GO:0009790 3052 0.169
embryo development ending in birth or egg hatching GO:0009792 2992 0.165
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.150
regulation of nitrogen compound metabolic process GO:0051171 222 0.143
signal transduction GO:0007165 317 0.140
positive regulation of rna biosynthetic process GO:1902680 102 0.124
multi organism reproductive process GO:0044703 867 0.113
single organism signaling GO:0044700 401 0.112
regulation of macromolecule metabolic process GO:0060255 421 0.110
regulation of multicellular organismal process GO:0051239 726 0.106
macromolecule localization GO:0033036 771 0.106
Worm
positive regulation of transcription dna templated GO:0045893 102 0.104
signaling GO:0023052 401 0.104
regulation of biological quality GO:0065008 741 0.100
Worm
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.097
muscle tissue development GO:0060537 1 0.097
regulation of neurogenesis GO:0050767 40 0.097
regulation of cellular metabolic process GO:0031323 305 0.095
organ development GO:0048513 1102 0.094
regulation of response to stimulus GO:0048583 243 0.086
Worm
positive regulation of macromolecule metabolic process GO:0010604 149 0.084
head development GO:0060322 1 0.084
cell death GO:0008219 547 0.083
positive regulation of cellular metabolic process GO:0031325 178 0.082
organic cyclic compound biosynthetic process GO:1901362 195 0.081
regulation of rna biosynthetic process GO:2001141 165 0.079
neuron development GO:0048666 199 0.078
regulation of gene expression GO:0010468 366 0.078
locomotion GO:0040011 1634 0.077
Worm
muscle organ development GO:0007517 26 0.075
negative regulation of gene expression GO:0010629 217 0.074
negative regulation of biological process GO:0048519 567 0.074
sex differentiation GO:0007548 909 0.074
response to chemical GO:0042221 356 0.073
Worm
nucleic acid templated transcription GO:0097659 169 0.073
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.072
cell surface receptor signaling pathway GO:0007166 149 0.072
lipid localization GO:0010876 573 0.070
Worm
rna metabolic process GO:0016070 228 0.069
cell development GO:0048468 696 0.069
cellular component assembly GO:0022607 293 0.068
positive regulation of multicellular organismal process GO:0051240 417 0.066
negative regulation of developmental process GO:0051093 227 0.065
single organism reproductive process GO:0044702 1196 0.065
transcription dna templated GO:0006351 168 0.065
regulation of multicellular organismal development GO:2000026 317 0.064
multi organism reproductive behavior GO:0044705 387 0.063
positive regulation of gene expression GO:0010628 112 0.062
lipid storage GO:0019915 565 0.061
Worm
regulation of metabolic process GO:0019222 478 0.061
hermaphrodite genitalia development GO:0040035 734 0.061
positive regulation of metabolic process GO:0009893 187 0.060
regulation of primary metabolic process GO:0080090 292 0.060
regulation of cellular biosynthetic process GO:0031326 189 0.059
multicellular organismal reproductive process GO:0048609 815 0.059
regulation of signaling GO:0023051 172 0.058
protein complex subunit organization GO:0071822 280 0.058
maintenance of location GO:0051235 580 0.058
Worm
rna biosynthetic process GO:0032774 169 0.056
macromolecule biosynthetic process GO:0009059 250 0.054
response to abiotic stimulus GO:0009628 152 0.054
Worm
body morphogenesis GO:0010171 620 0.054
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.053
muscle structure development GO:0061061 191 0.053
positive regulation of cellular biosynthetic process GO:0031328 109 0.052
regulation of cell differentiation GO:0045595 81 0.051
multicellular organismal aging GO:0010259 812 0.051
cytoskeleton organization GO:0007010 339 0.050
cell migration GO:0016477 306 0.049
defense response GO:0006952 296 0.049
multicellular organism reproduction GO:0032504 819 0.049
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.048
developmental process involved in reproduction GO:0003006 1165 0.048
cellular protein metabolic process GO:0044267 279 0.047
negative regulation of multicellular organismal process GO:0051241 236 0.047
neuron differentiation GO:0030182 217 0.047
nucleobase containing compound metabolic process GO:0006139 406 0.046
regulation of developmental process GO:0050793 684 0.045
organic substance biosynthetic process GO:1901576 323 0.045
cell cell signaling GO:0007267 118 0.044
ras protein signal transduction GO:0007265 31 0.043
negative regulation of neuron differentiation GO:0045665 4 0.043
developmental growth GO:0048589 412 0.042
regulation of macromolecule biosynthetic process GO:0010556 189 0.042
positive regulation of cellular process GO:0048522 332 0.042
regulation of behavior GO:0050795 97 0.042
Worm
vesicle mediated transport GO:0016192 852 0.042
molting cycle GO:0042303 281 0.042
multicellular organism growth GO:0035264 385 0.041
gene expression GO:0010467 412 0.041
multicellular organismal reproductive behavior GO:0033057 384 0.041
regulation of cell cycle GO:0051726 194 0.040
single organism organelle organization GO:1902589 501 0.040
single organism localization GO:1902578 518 0.039
cellular component movement GO:0006928 388 0.039
regulation of rna metabolic process GO:0051252 173 0.038
cellular component morphogenesis GO:0032989 318 0.038
negative regulation of metabolic process GO:0009892 240 0.038
regulation of developmental growth GO:0048638 389 0.038
cellular component biogenesis GO:0044085 297 0.037
sensory organ morphogenesis GO:0090596 2 0.037
mechanosensory behavior GO:0007638 25 0.036
Worm
reproductive behavior GO:0019098 387 0.036
canonical wnt signaling pathway GO:0060070 3 0.036
biosynthetic process GO:0009058 323 0.036
intracellular signal transduction GO:0035556 96 0.036
cellular protein complex assembly GO:0043623 178 0.035
protein complex biogenesis GO:0070271 186 0.035
genitalia development GO:0048806 741 0.035
response to external stimulus GO:0009605 289 0.035
Worm
multi organism behavior GO:0051705 389 0.035
endocytosis GO:0006897 819 0.035
positive regulation of multicellular organism growth GO:0040018 352 0.034
response to wounding GO:0009611 4 0.034
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.034
immune response GO:0006955 192 0.034
neurological system process GO:0050877 53 0.034
regulation of multicellular organism growth GO:0040014 373 0.034
negative regulation of neurogenesis GO:0050768 4 0.033
development of primary sexual characteristics GO:0045137 840 0.033
regulation of cell development GO:0060284 49 0.033
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.033
heterocycle biosynthetic process GO:0018130 187 0.032
cellular biosynthetic process GO:0044249 315 0.032
reproductive structure development GO:0048608 850 0.032
post embryonic organ development GO:0048569 336 0.032
memory GO:0007613 3 0.032
regulation of transcription dna templated GO:0006355 164 0.032
transcription from rna polymerase ii promoter GO:0006366 149 0.032
positive regulation of growth GO:0045927 369 0.031
death GO:0016265 547 0.031
oviposition GO:0018991 364 0.031
rho protein signal transduction GO:0007266 2 0.031
neuron projection development GO:0031175 187 0.030
aromatic compound biosynthetic process GO:0019438 192 0.030
nucleic acid metabolic process GO:0090304 299 0.030
gamete generation GO:0007276 461 0.030
regulation of cell communication GO:0010646 176 0.030
wnt signaling pathway GO:0016055 27 0.030
reproductive system development GO:0061458 850 0.030
nucleobase containing compound biosynthetic process GO:0034654 184 0.030
generation of neurons GO:0048699 235 0.030
cell type specific apoptotic process GO:0097285 4 0.030
aging GO:0007568 812 0.030
protein modification process GO:0036211 207 0.030
phosphate containing compound metabolic process GO:0006796 232 0.030
negative regulation of macromolecule metabolic process GO:0010605 229 0.029
negative regulation of nucleic acid templated transcription GO:1903507 53 0.029
vulval development GO:0040025 333 0.029
establishment of localization GO:0051234 1171 0.029
skeletal muscle organ development GO:0060538 3 0.029
cellular protein modification process GO:0006464 207 0.029
myofibril assembly GO:0030239 154 0.029
regulation of cell proliferation GO:0042127 105 0.028
protein metabolic process GO:0019538 422 0.028
cellular localization GO:0051641 360 0.028
single organism transport GO:0044765 447 0.028
cell motility GO:0048870 313 0.028
digestive system development GO:0055123 122 0.028
growth GO:0040007 562 0.028
positive regulation of developmental growth GO:0048639 354 0.028
muscle organ morphogenesis GO:0048644 4 0.028
positive regulation of rna metabolic process GO:0051254 103 0.028
protein complex assembly GO:0006461 186 0.027
positive regulation of biosynthetic process GO:0009891 109 0.027
negative regulation of cellular process GO:0048523 239 0.027
sexual reproduction GO:0019953 546 0.027
establishment of localization in cell GO:0051649 318 0.027
purine nucleoside metabolic process GO:0042278 92 0.027
cellular macromolecule biosynthetic process GO:0034645 247 0.027
organelle organization GO:0006996 783 0.027
determination of adult lifespan GO:0008340 812 0.026
regulation of nervous system development GO:0051960 41 0.026
striated muscle cell differentiation GO:0051146 158 0.026
gonad development GO:0008406 840 0.026
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.025
macromolecular complex subunit organization GO:0043933 320 0.025
taxis GO:0042330 128 0.025
Worm
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.025
tissue development GO:0009888 112 0.024
neuron recognition GO:0008038 83 0.024
protein localization GO:0008104 205 0.024
regulation of signal transduction GO:0009966 135 0.024
actin filament based process GO:0030029 191 0.024
cell projection organization GO:0030030 231 0.024
cell cycle process GO:0022402 482 0.024
macromolecular complex assembly GO:0065003 193 0.024
cell fate commitment GO:0045165 139 0.023
negative regulation of biosynthetic process GO:0009890 65 0.023
positive regulation of developmental process GO:0051094 408 0.023
regulation of organ morphogenesis GO:2000027 4 0.023
response to heat GO:0009408 50 0.023
negative regulation of cellular biosynthetic process GO:0031327 65 0.023
regulation of post embryonic development GO:0048580 260 0.023
macromolecule modification GO:0043412 218 0.023
microtubule based process GO:0007017 182 0.023
germ cell development GO:0007281 351 0.023
programmed cell death GO:0012501 500 0.022
positive regulation of intracellular transport GO:0032388 2 0.022
striated muscle cell development GO:0055002 157 0.022
cell morphogenesis GO:0000902 163 0.022
positive regulation of catalytic activity GO:0043085 59 0.022
response to osmotic stress GO:0006970 29 0.022
Worm
nervous system development GO:0007399 253 0.022
cellular macromolecular complex assembly GO:0034622 184 0.021
regulation of growth GO:0040008 409 0.021
epithelial tube morphogenesis GO:0060562 1 0.021
regulation of biosynthetic process GO:0009889 189 0.021
microtubule polymerization or depolymerization GO:0031109 22 0.021
response to mechanical stimulus GO:0009612 28 0.021
Worm
positive regulation of molecular function GO:0044093 61 0.021
organophosphate metabolic process GO:0019637 125 0.021
female gamete generation GO:0007292 254 0.021
regulation of mitotic cell cycle GO:0007346 76 0.021
multi multicellular organism process GO:0044706 390 0.021
tissue morphogenesis GO:0048729 65 0.020
axon development GO:0061564 163 0.020
regulation of localization GO:0032879 194 0.020
positive regulation of ras gtpase activity GO:0032320 19 0.020
cell cycle GO:0007049 526 0.020
cell projection morphogenesis GO:0048858 148 0.019
cellular protein localization GO:0034613 75 0.019
organelle assembly GO:0070925 214 0.019
chemosensory behavior GO:0007635 33 0.019
regulation of cell death GO:0010941 65 0.019
negative regulation of transcription from rna polymerase ii promoter GO:0000122 45 0.019
neuron projection morphogenesis GO:0048812 114 0.019
regulation of ras protein signal transduction GO:0046578 41 0.019
positive regulation of neuron differentiation GO:0045666 4 0.019
actomyosin structure organization GO:0031032 154 0.019
regulation of programmed cell death GO:0043067 50 0.018
regulation of nucleic acid templated transcription GO:1903506 165 0.018
nucleoside triphosphate metabolic process GO:0009141 87 0.018
single organism behavior GO:0044708 83 0.018
Worm
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.018
catabolic process GO:0009056 318 0.018
small gtpase mediated signal transduction GO:0007264 32 0.018
vesicle localization GO:0051648 24 0.018
regulation of lipid metabolic process GO:0019216 4 0.018
enzyme linked receptor protein signaling pathway GO:0007167 50 0.018
neurogenesis GO:0022008 236 0.018
positive regulation of phosphorus metabolic process GO:0010562 56 0.018
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.018
small molecule metabolic process GO:0044281 186 0.018
muscle cell development GO:0055001 158 0.017
single organism catabolic process GO:0044712 129 0.017
cellular component assembly involved in morphogenesis GO:0010927 183 0.017
regulation of neuron differentiation GO:0045664 40 0.017
carbohydrate derivative metabolic process GO:1901135 141 0.017
regulation of nematode larval development GO:0061062 260 0.017
negative regulation of cellular metabolic process GO:0031324 95 0.017
sensory perception of taste GO:0050909 4 0.016
negative regulation of cell morphogenesis involved in differentiation GO:0010771 2 0.016
heterocycle catabolic process GO:0046700 119 0.016
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.016
regulation of epithelial cell proliferation GO:0050678 1 0.016
cell proliferation GO:0008283 116 0.016
regulation of cellular catabolic process GO:0031329 51 0.016
purine ribonucleotide metabolic process GO:0009150 95 0.016
cellular nitrogen compound biosynthetic process GO:0044271 192 0.016
regulation of cell cycle process GO:0010564 145 0.015
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.015
cellular catabolic process GO:0044248 199 0.015
organic substance transport GO:0071702 113 0.015
dauer larval development GO:0040024 92 0.015
negative regulation of signaling GO:0023057 61 0.015
cell division GO:0051301 262 0.015
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.015
phosphorylation GO:0016310 116 0.015
establishment of synaptic vesicle localization GO:0097480 21 0.015
system process GO:0003008 136 0.015
regulation of apoptotic process GO:0042981 36 0.015
directional locomotion GO:0033058 14 0.015
Worm
nucleobase containing compound catabolic process GO:0034655 114 0.015
regulation of intracellular signal transduction GO:1902531 77 0.015
phosphorus metabolic process GO:0006793 232 0.015
axon guidance GO:0007411 82 0.015
digestive tract morphogenesis GO:0048546 76 0.015
regulation of vulval development GO:0040028 248 0.015
organic substance catabolic process GO:1901575 294 0.015
regulation of cellular component organization GO:0051128 248 0.014
nucleoside catabolic process GO:0009164 78 0.014
synaptic transmission GO:0007268 106 0.014
purine nucleoside catabolic process GO:0006152 75 0.014
negative regulation of rna metabolic process GO:0051253 53 0.014
regulation of locomotion GO:0040012 161 0.014
Worm
muscle cell differentiation GO:0042692 171 0.014
regulation of cellular ketone metabolic process GO:0010565 3 0.014
membrane invagination GO:0010324 98 0.014
myosin filament organization GO:0031033 138 0.014
posttranscriptional regulation of gene expression GO:0010608 166 0.014
regulation of stem cell differentiation GO:2000736 1 0.014
lipid metabolic process GO:0006629 77 0.014
protein phosphorylation GO:0006468 85 0.014
aromatic compound catabolic process GO:0019439 116 0.014
pigmentation GO:0043473 2 0.013
positive regulation of response to stimulus GO:0048584 55 0.013
neuron projection guidance GO:0097485 82 0.013
nucleoside phosphate metabolic process GO:0006753 108 0.013
cell part morphogenesis GO:0032990 152 0.013
regulation of organelle organization GO:0033043 164 0.013
positive regulation of neurogenesis GO:0050769 4 0.013
response to external biotic stimulus GO:0043207 101 0.013
muscle fiber development GO:0048747 2 0.013
developmental induction GO:0031128 1 0.013
regulation of cytoplasmic transport GO:1903649 3 0.013
ectoderm development GO:0007398 3 0.013
apoptotic process GO:0006915 478 0.013
positive regulation of cell cycle GO:0045787 55 0.013
receptor mediated endocytosis GO:0006898 715 0.013
regulation of phosphate metabolic process GO:0019220 81 0.013
cellular lipid metabolic process GO:0044255 40 0.013
signal release GO:0023061 28 0.013
cellular macromolecule localization GO:0070727 75 0.013
defense response to other organism GO:0098542 100 0.013
hormone transport GO:0009914 2 0.013
glycosyl compound catabolic process GO:1901658 79 0.013
organonitrogen compound metabolic process GO:1901564 151 0.013
autophagy GO:0006914 29 0.013
nucleoside metabolic process GO:0009116 99 0.013
nucleoside phosphate catabolic process GO:1901292 77 0.013
regulation of reproductive process GO:2000241 66 0.012
cuticle development GO:0042335 100 0.012
proteolysis GO:0006508 61 0.012
regulation of nucleoside metabolic process GO:0009118 37 0.012
nucleoside triphosphate catabolic process GO:0009143 72 0.012
regulation of synaptic plasticity GO:0048167 1 0.012
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 2 0.012
hormone secretion GO:0046879 2 0.012
regulation of multi organism process GO:0043900 69 0.012
chemotaxis GO:0006935 120 0.012
Worm
positive regulation of protein transport GO:0051222 4 0.012
regulation of gene expression epigenetic GO:0040029 163 0.012
oogenesis GO:0048477 229 0.012
cell morphogenesis involved in differentiation GO:0000904 112 0.012
adult behavior GO:0030534 3 0.012
establishment or maintenance of cell polarity GO:0007163 63 0.012
epithelium development GO:0060429 68 0.012
regulation of nucleocytoplasmic transport GO:0046822 3 0.012
localization of cell GO:0051674 313 0.011
cell recognition GO:0008037 85 0.011
positive regulation of stem cell differentiation GO:2000738 1 0.011
apoptotic cell clearance GO:0043277 111 0.011
regulation of apoptotic signaling pathway GO:2001233 1 0.011
regulation of development heterochronic GO:0040034 18 0.011
olfactory behavior GO:0042048 27 0.011
gene silencing GO:0016458 143 0.011
regulation of protein stability GO:0031647 3 0.011
establishment of vesicle localization GO:0051650 23 0.011
regulation of cellular protein metabolic process GO:0032268 75 0.011
negative regulation of response to stimulus GO:0048585 73 0.011
embryonic morphogenesis GO:0048598 152 0.011
nucleobase containing small molecule metabolic process GO:0055086 115 0.011
striated muscle myosin thick filament assembly GO:0071688 138 0.011
regulation of cell morphogenesis involved in differentiation GO:0010769 29 0.011
amine metabolic process GO:0009308 15 0.011
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 16 0.011
organic cyclic compound catabolic process GO:1901361 119 0.011
neurotransmitter secretion GO:0007269 26 0.011
regulation of neurotransmitter levels GO:0001505 36 0.011
protein oligomerization GO:0051259 4 0.011
nucleotide metabolic process GO:0009117 108 0.011
purine containing compound catabolic process GO:0072523 75 0.011
positive regulation of gtp catabolic process GO:0033126 28 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.011
anatomical structure formation involved in morphogenesis GO:0048646 250 0.011
positive regulation of organ growth GO:0046622 4 0.011
organophosphate catabolic process GO:0046434 81 0.011
regulation of canonical wnt signaling pathway GO:0060828 1 0.011
secretion by cell GO:0032940 138 0.011
regulation of muscle cell differentiation GO:0051147 1 0.010
ribonucleotide metabolic process GO:0009259 99 0.010
regulation of neuron projection development GO:0010975 31 0.010
rna interference GO:0016246 137 0.010
tube development GO:0035295 126 0.010
bmp signaling pathway GO:0030509 3 0.010
negative regulation of transcription dna templated GO:0045892 53 0.010
regulation of pharyngeal pumping GO:0043051 36 0.010
regeneration GO:0031099 4 0.010
actin cytoskeleton organization GO:0030036 184 0.010
regulation of catalytic activity GO:0050790 78 0.010
response to organic substance GO:0010033 131 0.010
negative regulation of cell cycle GO:0045786 53 0.010
purine containing compound metabolic process GO:0072521 95 0.010
purine nucleoside triphosphate metabolic process GO:0009144 87 0.010
peptidyl tyrosine phosphorylation GO:0018108 2 0.010
glycosyl compound metabolic process GO:1901657 100 0.010
regulation of protein import into nucleus GO:0042306 3 0.010
secretion GO:0046903 147 0.010
regulation of phosphorylation GO:0042325 45 0.010
positive regulation of purine nucleotide metabolic process GO:1900544 28 0.010
peptide hormone secretion GO:0030072 2 0.010
response to acid chemical GO:0001101 4 0.010
positive regulation of cell morphogenesis involved in differentiation GO:0010770 4 0.010

exp-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.019
disease of cellular proliferation DOID:14566 0 0.017
cancer DOID:162 0 0.014
organ system cancer DOID:0050686 0 0.012
nervous system disease DOID:863 0 0.011