Caenorhabditis elegans

83 known processes

spd-5 (CELE_F56A3.4)

Protein SPD-5

spd-5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cell cycle process GO:0022402 482 0.851
embryo development ending in birth or egg hatching GO:0009792 2992 0.851
organelle organization GO:0006996 783 0.839
organ development GO:0048513 1102 0.811
embryo development GO:0009790 3052 0.794
mitotic cell cycle process GO:1903047 194 0.769
sex differentiation GO:0007548 909 0.760
post embryonic development GO:0009791 2152 0.706
establishment of localization GO:0051234 1171 0.696
development of primary sexual characteristics GO:0045137 840 0.681
reproductive system development GO:0061458 850 0.675
reproductive structure development GO:0048608 850 0.669
gonad development GO:0008406 840 0.590
locomotion GO:0040011 1634 0.563
cell cycle GO:0007049 526 0.550
hermaphrodite genitalia development GO:0040035 734 0.538
organic substance catabolic process GO:1901575 294 0.501
multicellular organism reproduction GO:0032504 819 0.453
germ cell development GO:0007281 351 0.448
regulation of developmental process GO:0050793 684 0.436
developmental process involved in reproduction GO:0003006 1165 0.420
single organism reproductive process GO:0044702 1196 0.397
microtubule based process GO:0007017 182 0.391
meiotic cell cycle GO:0051321 335 0.379
transport GO:0006810 1093 0.364
spindle organization GO:0007051 92 0.339
genitalia development GO:0048806 741 0.332
macromolecular complex subunit organization GO:0043933 320 0.331
receptor mediated endocytosis GO:0006898 715 0.329
cytoskeleton organization GO:0007010 339 0.324
single organism organelle organization GO:1902589 501 0.323
regulation of transcription dna templated GO:0006355 164 0.310
multicellular organismal reproductive process GO:0048609 815 0.302
cell death GO:0008219 547 0.301
signaling GO:0023052 401 0.276
regulation of phosphorus metabolic process GO:0051174 81 0.275
single organism signaling GO:0044700 401 0.270
single organism localization GO:1902578 518 0.268
regulation of cell cycle GO:0051726 194 0.261
negative regulation of biological process GO:0048519 567 0.261
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.257
cellular protein modification process GO:0006464 207 0.250
vulval development GO:0040025 333 0.250
macromolecule modification GO:0043412 218 0.245
multicellular organismal reproductive behavior GO:0033057 384 0.240
gamete generation GO:0007276 461 0.239
multi organism reproductive process GO:0044703 867 0.237
cellular localization GO:0051641 360 0.235
meiotic nuclear division GO:0007126 300 0.226
regulation of multicellular organismal process GO:0051239 726 0.223
regulation of response to stimulus GO:0048583 243 0.215
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.214
regulation of metabolic process GO:0019222 478 0.207
rna biosynthetic process GO:0032774 169 0.202
positive regulation of multicellular organismal process GO:0051240 417 0.201
programmed cell death GO:0012501 500 0.198
establishment of localization in cell GO:0051649 318 0.197
female gamete generation GO:0007292 254 0.191
regulation of cellular metabolic process GO:0031323 305 0.189
phosphorylation GO:0016310 116 0.185
positive regulation of developmental process GO:0051094 408 0.183
phosphate containing compound metabolic process GO:0006796 232 0.173
oviposition GO:0018991 364 0.171
determination of adult lifespan GO:0008340 812 0.171
aromatic compound biosynthetic process GO:0019438 192 0.170
nucleic acid templated transcription GO:0097659 169 0.170
cell motility GO:0048870 313 0.170
neuron differentiation GO:0030182 217 0.166
phosphorus metabolic process GO:0006793 232 0.162
meiotic cell cycle process GO:1903046 170 0.150
regulation of macromolecule metabolic process GO:0060255 421 0.148
regulation of intracellular signal transduction GO:1902531 77 0.147
macromolecular complex assembly GO:0065003 193 0.147
negative regulation of cell cycle GO:0045786 53 0.147
negative regulation of metabolic process GO:0009892 240 0.147
apoptotic process GO:0006915 478 0.145
multi multicellular organism process GO:0044706 390 0.139
multicellular organism growth GO:0035264 385 0.137
growth GO:0040007 562 0.137
gene expression GO:0010467 412 0.137
protein catabolic process GO:0030163 162 0.134
aging GO:0007568 812 0.131
body morphogenesis GO:0010171 620 0.129
regulation of gene expression GO:0010468 366 0.127
immune response GO:0006955 192 0.126
oogenesis GO:0048477 229 0.125
death GO:0016265 547 0.124
developmental growth GO:0048589 412 0.124
regulation of nucleic acid templated transcription GO:1903506 165 0.123
defense response GO:0006952 296 0.123
negative regulation of cellular process GO:0048523 239 0.121
sexual reproduction GO:0019953 546 0.120
multi organism behavior GO:0051705 389 0.119
vesicle mediated transport GO:0016192 852 0.118
macromolecule localization GO:0033036 771 0.118
localization of cell GO:0051674 313 0.118
negative regulation of cellular metabolic process GO:0031324 95 0.117
molting cycle GO:0042303 281 0.114
regulation of mitotic cell cycle GO:0007346 76 0.112
protein modification process GO:0036211 207 0.110
regulation of gene expression epigenetic GO:0040029 163 0.109
positive regulation of multicellular organism growth GO:0040018 352 0.109
regulation of biological quality GO:0065008 741 0.107
maintenance of location in cell GO:0051651 12 0.106
regulation of macromolecule biosynthetic process GO:0010556 189 0.103
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.103
multicellular organismal aging GO:0010259 812 0.102
regulation of cellular biosynthetic process GO:0031326 189 0.101
organelle assembly GO:0070925 214 0.101
endocytosis GO:0006897 819 0.100
regulation of nematode larval development GO:0061062 260 0.098
response to external stimulus GO:0009605 289 0.095
transcription dna templated GO:0006351 168 0.094
chromosome organization GO:0051276 104 0.094
negative regulation of cellular biosynthetic process GO:0031327 65 0.094
reproductive behavior GO:0019098 387 0.093
regulation of multicellular organismal development GO:2000026 317 0.093
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.092
positive regulation of growth GO:0045927 369 0.089
regulation of biosynthetic process GO:0009889 189 0.088
actin cytoskeleton organization GO:0030036 184 0.088
negative regulation of macromolecule metabolic process GO:0010605 229 0.087
cell migration GO:0016477 306 0.087
regulation of signaling GO:0023051 172 0.085
behavior GO:0007610 527 0.085
intracellular signal transduction GO:0035556 96 0.084
regulation of multicellular organism growth GO:0040014 373 0.084
negative regulation of gene expression GO:0010629 217 0.082
single organism transport GO:0044765 447 0.082
positive regulation of cellular metabolic process GO:0031325 178 0.081
regulation of primary metabolic process GO:0080090 292 0.081
regulation of cell cycle process GO:0010564 145 0.080
transcription from rna polymerase ii promoter GO:0006366 149 0.080
organelle fission GO:0048285 363 0.079
regulation of rna biosynthetic process GO:2001141 165 0.076
heterocycle biosynthetic process GO:0018130 187 0.073
purine containing compound catabolic process GO:0072523 75 0.072
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.072
response to chemical GO:0042221 356 0.071
cellular protein complex assembly GO:0043623 178 0.070
regulation of developmental growth GO:0048638 389 0.070
response to wounding GO:0009611 4 0.069
cellular macromolecule localization GO:0070727 75 0.069
regulation of cellular component organization GO:0051128 248 0.068
regulation of signal transduction GO:0009966 135 0.067
negative regulation of multicellular organismal process GO:0051241 236 0.067
maintenance of location GO:0051235 580 0.066
cell division GO:0051301 262 0.066
cellular component movement GO:0006928 388 0.064
response to oxygen containing compound GO:1901700 44 0.064
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.064
chromosome segregation GO:0007059 180 0.064
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.063
cell development GO:0048468 696 0.063
regulation of growth GO:0040008 409 0.062
catabolic process GO:0009056 318 0.062
regulation of cell communication GO:0010646 176 0.060
response to organic substance GO:0010033 131 0.060
protein metabolic process GO:0019538 422 0.059
cellular response to stress GO:0033554 162 0.058
negative regulation of biosynthetic process GO:0009890 65 0.058
regulation of catalytic activity GO:0050790 78 0.058
cellular protein metabolic process GO:0044267 279 0.058
negative regulation of transcription from rna polymerase ii promoter GO:0000122 45 0.057
nucleobase containing compound metabolic process GO:0006139 406 0.057
nucleic acid metabolic process GO:0090304 299 0.057
cellular biosynthetic process GO:0044249 315 0.057
generation of neurons GO:0048699 235 0.057
purine nucleoside metabolic process GO:0042278 92 0.056
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.056
head development GO:0060322 1 0.056
positive regulation of rna metabolic process GO:0051254 103 0.056
lipid localization GO:0010876 573 0.056
organic substance biosynthetic process GO:1901576 323 0.055
post embryonic organ development GO:0048569 336 0.054
mitotic spindle organization GO:0007052 81 0.054
lipid storage GO:0019915 565 0.054
signal transduction GO:0007165 317 0.054
regulation of molecular function GO:0065009 89 0.053
regulation of organelle organization GO:0033043 164 0.052
positive regulation of signaling GO:0023056 66 0.052
posttranscriptional regulation of gene expression GO:0010608 166 0.050
regulation of protein metabolic process GO:0051246 81 0.049
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 20 0.049
small molecule metabolic process GO:0044281 186 0.049
cellular component assembly GO:0022607 293 0.049
regulation of post embryonic development GO:0048580 260 0.047
neuron projection development GO:0031175 187 0.047
neurogenesis GO:0022008 236 0.046
chromatin organization GO:0006325 32 0.046
neuron development GO:0048666 199 0.046
negative regulation of vulval development GO:0040027 206 0.045
regulation of phosphorylation GO:0042325 45 0.045
purine nucleotide metabolic process GO:0006163 95 0.045
response to abiotic stimulus GO:0009628 152 0.044
nucleobase containing compound biosynthetic process GO:0034654 184 0.044
spindle localization GO:0051653 51 0.043
cellular macromolecular complex assembly GO:0034622 184 0.043
organelle localization GO:0051640 127 0.043
positive regulation of cellular biosynthetic process GO:0031328 109 0.042
cellular response to chemical stimulus GO:0070887 129 0.042
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.041
cellular catabolic process GO:0044248 199 0.041
anatomical structure formation involved in morphogenesis GO:0048646 250 0.041
cellular component morphogenesis GO:0032989 318 0.041
cellular protein localization GO:0034613 75 0.040
positive regulation of developmental growth GO:0048639 354 0.040
carbohydrate derivative metabolic process GO:1901135 141 0.040
regulation of phosphate metabolic process GO:0019220 81 0.039
regulation of protein localization GO:0032880 50 0.038
innate immune response GO:0045087 190 0.038
cellular component assembly involved in morphogenesis GO:0010927 183 0.038
negative regulation of developmental process GO:0051093 227 0.038
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.037
macromolecule catabolic process GO:0009057 202 0.037
actin filament based process GO:0030029 191 0.037
system process GO:0003008 136 0.037
positive regulation of transcription dna templated GO:0045893 102 0.037
cellular macromolecule biosynthetic process GO:0034645 247 0.036
modification dependent protein catabolic process GO:0019941 32 0.036
female meiotic division GO:0007143 17 0.035
posttranscriptional gene silencing GO:0016441 143 0.035
cellular response to organic substance GO:0071310 119 0.035
organic acid metabolic process GO:0006082 47 0.034
ribonucleoside metabolic process GO:0009119 98 0.034
nervous system development GO:0007399 253 0.034
protein complex subunit organization GO:0071822 280 0.033
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.033
positive regulation of response to stimulus GO:0048584 55 0.033
organic cyclic compound biosynthetic process GO:1901362 195 0.033
single organism catabolic process GO:0044712 129 0.032
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.032
protein complex biogenesis GO:0070271 186 0.032
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.032
cell projection morphogenesis GO:0048858 148 0.032
myofibril assembly GO:0030239 154 0.031
single fertilization GO:0007338 61 0.031
regulation of vulval development GO:0040028 248 0.031
protein complex assembly GO:0006461 186 0.031
mitotic g2 m transition checkpoint GO:0044818 1 0.030
regulation of rna metabolic process GO:0051252 173 0.030
striated muscle cell differentiation GO:0051146 158 0.030
carboxylic acid metabolic process GO:0019752 34 0.030
organic cyclic compound catabolic process GO:1901361 119 0.030
purine nucleoside triphosphate metabolic process GO:0009144 87 0.030
modification dependent macromolecule catabolic process GO:0043632 32 0.030
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.029
posttranscriptional gene silencing by rna GO:0035194 143 0.029
biosynthetic process GO:0009058 323 0.029
ribonucleoside triphosphate metabolic process GO:0009199 87 0.029
ubiquitin dependent protein catabolic process GO:0006511 32 0.028
gene silencing GO:0016458 143 0.028
covalent chromatin modification GO:0016569 30 0.028
purine ribonucleoside metabolic process GO:0046128 92 0.028
rna metabolic process GO:0016070 228 0.028
organophosphate metabolic process GO:0019637 125 0.027
protein phosphorylation GO:0006468 85 0.027
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.027
regulation of nitrogen compound metabolic process GO:0051171 222 0.027
negative regulation of nucleic acid templated transcription GO:1903507 53 0.026
multi organism reproductive behavior GO:0044705 387 0.026
regulation of cellular catabolic process GO:0031329 51 0.026
neurological system process GO:0050877 53 0.026
muscle cell development GO:0055001 158 0.026
defense response to other organism GO:0098542 100 0.025
positive regulation of metabolic process GO:0009893 187 0.025
oxoacid metabolic process GO:0043436 47 0.025
regulation of localization GO:0032879 194 0.025
muscle cell differentiation GO:0042692 171 0.024
protein localization to organelle GO:0033365 37 0.024
dna metabolic process GO:0006259 74 0.024
rna interference GO:0016246 137 0.024
striated muscle cell development GO:0055002 157 0.024
negative regulation of mitotic cell cycle GO:0045930 42 0.024
signal transduction by phosphorylation GO:0023014 31 0.024
cellular nitrogen compound biosynthetic process GO:0044271 192 0.023
regulation of cytoplasmic transport GO:1903649 3 0.023
negative regulation of signal transduction GO:0009968 60 0.023
striated muscle myosin thick filament assembly GO:0071688 138 0.023
ribose phosphate metabolic process GO:0019693 99 0.023
response to endogenous stimulus GO:0009719 33 0.022
meiotic chromosome segregation GO:0045132 139 0.022
negative regulation of rna biosynthetic process GO:1902679 53 0.022
proteolysis involved in cellular protein catabolic process GO:0051603 32 0.022
macromolecule biosynthetic process GO:0009059 250 0.022
regulation of cellular response to stress GO:0080135 19 0.022
regulation of cellular protein metabolic process GO:0032268 75 0.022
positive regulation of signal transduction GO:0009967 40 0.022
aromatic compound catabolic process GO:0019439 116 0.021
nucleobase containing small molecule metabolic process GO:0055086 115 0.021
peptidyl tyrosine phosphorylation GO:0018108 2 0.021
positive regulation of biosynthetic process GO:0009891 109 0.021
myosin filament organization GO:0031033 138 0.021
regulation of cell death GO:0010941 65 0.021
positive regulation of intracellular signal transduction GO:1902533 24 0.021
regulation of catabolic process GO:0009894 57 0.021
single organism cellular localization GO:1902580 72 0.021
purine containing compound metabolic process GO:0072521 95 0.021
inductive cell migration GO:0040039 145 0.020
cell type specific apoptotic process GO:0097285 4 0.020
positive regulation of cell morphogenesis involved in differentiation GO:0010770 4 0.020
cell proliferation GO:0008283 116 0.020
actomyosin structure organization GO:0031032 154 0.020
organonitrogen compound catabolic process GO:1901565 90 0.019
positive regulation of cell communication GO:0010647 69 0.019
protein modification by small protein conjugation or removal GO:0070647 40 0.019
organonitrogen compound metabolic process GO:1901564 151 0.019
ras protein signal transduction GO:0007265 31 0.019
carbohydrate derivative catabolic process GO:1901136 82 0.019
cytokinesis GO:0000910 80 0.019
positive regulation of neuron projection development GO:0010976 4 0.019
cell morphogenesis involved in differentiation GO:0000904 112 0.019
nucleoside triphosphate metabolic process GO:0009141 87 0.018
positive regulation of gene expression GO:0010628 112 0.018
histone modification GO:0016570 30 0.018
gene silencing by rna GO:0031047 143 0.018
proteolysis GO:0006508 61 0.018
protein localization GO:0008104 205 0.018
cell morphogenesis GO:0000902 163 0.017
cellular response to oxygen containing compound GO:1901701 21 0.017
intracellular receptor signaling pathway GO:0030522 2 0.017
cellular macromolecule catabolic process GO:0044265 73 0.017
heterocycle catabolic process GO:0046700 119 0.017
mitotic sister chromatid segregation GO:0000070 38 0.016
chemotaxis GO:0006935 120 0.016
negative regulation of post embryonic development GO:0048581 208 0.016
locomotory behavior GO:0007626 40 0.016
response to external biotic stimulus GO:0043207 101 0.016
cell maturation GO:0048469 26 0.016
regulation of hydrolase activity GO:0051336 45 0.016
purine ribonucleotide catabolic process GO:0009154 75 0.016
regulation of cellular ketone metabolic process GO:0010565 3 0.016
nucleoside phosphate metabolic process GO:0006753 108 0.016
homeostatic process GO:0042592 51 0.016
negative regulation of cellular protein metabolic process GO:0032269 27 0.016
defense response to bacterium GO:0042742 86 0.015
cell projection organization GO:0030030 231 0.015
regulation of apoptotic signaling pathway GO:2001233 1 0.015
digestive system development GO:0055123 122 0.015
cellular component biogenesis GO:0044085 297 0.015
peptidyl amino acid modification GO:0018193 58 0.015
ribonucleotide metabolic process GO:0009259 99 0.015
regulation of nucleotide metabolic process GO:0006140 37 0.015
muscle structure development GO:0061061 191 0.015
positive regulation of cellular process GO:0048522 332 0.015
nucleotide metabolic process GO:0009117 108 0.015
negative regulation of signaling GO:0023057 61 0.015
organic substance transport GO:0071702 113 0.014
cellular amino acid metabolic process GO:0006520 15 0.014
purine nucleotide catabolic process GO:0006195 75 0.014
muscle tissue development GO:0060537 1 0.014
regulation of nucleocytoplasmic transport GO:0046822 3 0.014
response to biotic stimulus GO:0009607 101 0.014
cellular protein catabolic process GO:0044257 37 0.014
positive regulation of rna biosynthetic process GO:1902680 102 0.014
male anatomical structure morphogenesis GO:0090598 78 0.014
negative regulation of cell cycle process GO:0010948 12 0.014
positive regulation of phosphorus metabolic process GO:0010562 56 0.014
nucleoside triphosphate catabolic process GO:0009143 72 0.014
myosin filament assembly GO:0031034 138 0.014
response to bacterium GO:0009617 86 0.014
male gamete generation GO:0048232 41 0.014
negative regulation of nematode larval development GO:0061064 208 0.013
nucleoside metabolic process GO:0009116 99 0.013
regulation of purine nucleotide metabolic process GO:1900542 37 0.013
nucleoside catabolic process GO:0009164 78 0.013
response to ketone GO:1901654 1 0.013
positive regulation of neuron differentiation GO:0045666 4 0.013
negative regulation of mitotic cell cycle phase transition GO:1901991 5 0.013
nucleobase containing compound catabolic process GO:0034655 114 0.013
negative regulation of gene expression epigenetic GO:0045814 2 0.013
purine nucleoside triphosphate catabolic process GO:0009146 72 0.013
secretion GO:0046903 147 0.013
mitotic nuclear division GO:0007067 89 0.013
regulation of cellular localization GO:0060341 42 0.013
cytoskeleton dependent cytokinesis GO:0061640 35 0.012
response to other organism GO:0051707 101 0.012
positive regulation of nucleic acid templated transcription GO:1903508 102 0.012
response to inorganic substance GO:0010035 50 0.012
positive regulation of cellular catabolic process GO:0031331 35 0.012
dendrite development GO:0016358 42 0.012
regulation of nucleoside metabolic process GO:0009118 37 0.012
membrane invagination GO:0010324 98 0.012
purine ribonucleoside catabolic process GO:0046130 75 0.012
regulation of meiotic cell cycle GO:0051445 136 0.012
ribonucleoside triphosphate catabolic process GO:0009203 72 0.012
purine ribonucleotide metabolic process GO:0009150 95 0.012
positive regulation of neurogenesis GO:0050769 4 0.011
single organism carbohydrate metabolic process GO:0044723 29 0.011
establishment of organelle localization GO:0051656 123 0.011
small gtpase mediated signal transduction GO:0007264 32 0.011
positive regulation of cellular component organization GO:0051130 34 0.011
regulation of cell development GO:0060284 49 0.011
regulation of programmed cell death GO:0043067 50 0.011
taxis GO:0042330 128 0.011
peptidyl tyrosine modification GO:0018212 3 0.011
positive regulation of macromolecule metabolic process GO:0010604 149 0.011
regulation of small gtpase mediated signal transduction GO:0051056 41 0.011
regulation of response to stress GO:0080134 28 0.011
negative regulation of response to stimulus GO:0048585 73 0.011
nucleus organization GO:0006997 38 0.011
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.011
regulation of cellular amine metabolic process GO:0033238 0 0.011
neuromuscular junction development GO:0007528 2 0.010
regulation of protein import into nucleus GO:0042306 3 0.010
negative regulation of protein metabolic process GO:0051248 27 0.010
neuron apoptotic process GO:0051402 4 0.010
nucleus localization GO:0051647 55 0.010
apoptotic cell clearance GO:0043277 111 0.010
canonical wnt signaling pathway GO:0060070 3 0.010
regulation of cell proliferation GO:0042127 105 0.010
secretion by cell GO:0032940 138 0.010
positive regulation of catabolic process GO:0009896 38 0.010
phagocytosis engulfment GO:0006911 98 0.010

spd-5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.040
nervous system disease DOID:863 0 0.017