Caenorhabditis elegans

11 known processes

shn-1 (CELE_C33B4.3)

Protein SHN-1

shn-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
locomotion GO:0040011 1634 0.502
regulation of rna biosynthetic process GO:2001141 165 0.438
neuron development GO:0048666 199 0.370
Mouse Rat
response to chemical GO:0042221 356 0.369
Mouse Rat
regulation of signal transduction GO:0009966 135 0.333
Mouse Rat
regulation of nitrogen compound metabolic process GO:0051171 222 0.322
embryo development ending in birth or egg hatching GO:0009792 2992 0.313
organ development GO:0048513 1102 0.295
Mouse Rat
neuron differentiation GO:0030182 217 0.292
Mouse Rat
multicellular organismal aging GO:0010259 812 0.275
post embryonic development GO:0009791 2152 0.252
cell development GO:0048468 696 0.246
Mouse Rat
cell cycle process GO:0022402 482 0.233
single organism organelle organization GO:1902589 501 0.231
Mouse
signal transduction GO:0007165 317 0.224
Mouse Rat
negative regulation of transcription dna templated GO:0045892 53 0.214
regulation of biological quality GO:0065008 741 0.207
Mouse
vulval development GO:0040025 333 0.202
sex differentiation GO:0007548 909 0.193
macromolecule localization GO:0033036 771 0.183
Mouse
single organism reproductive process GO:0044702 1196 0.180
post embryonic organ development GO:0048569 336 0.177
regulation of developmental process GO:0050793 684 0.172
Mouse Rat
molting cycle GO:0042303 281 0.165
positive regulation of developmental process GO:0051094 408 0.162
Mouse Rat
reproductive structure development GO:0048608 850 0.158
axon development GO:0061564 163 0.157
determination of adult lifespan GO:0008340 812 0.153
positive regulation of multicellular organismal process GO:0051240 417 0.149
Mouse Rat
gene expression GO:0010467 412 0.146
cellular component biogenesis GO:0044085 297 0.144
Mouse Rat
cell migration GO:0016477 306 0.142
regulation of metabolic process GO:0019222 478 0.139
aging GO:0007568 812 0.137
cellular macromolecule biosynthetic process GO:0034645 247 0.136
nucleic acid metabolic process GO:0090304 299 0.136
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.135
multicellular organismal reproductive process GO:0048609 815 0.132
cellular component assembly GO:0022607 293 0.131
Mouse Rat
sexual reproduction GO:0019953 546 0.130
multicellular organism reproduction GO:0032504 819 0.128
regulation of multicellular organismal process GO:0051239 726 0.126
Mouse Rat
embryo development GO:0009790 3052 0.126
Mouse
cellular component morphogenesis GO:0032989 318 0.123
Mouse
gamete generation GO:0007276 461 0.122
regulation of cellular metabolic process GO:0031323 305 0.120
establishment of localization GO:0051234 1171 0.116
Mouse
developmental process involved in reproduction GO:0003006 1165 0.115
positive regulation of growth GO:0045927 369 0.110
reproductive system development GO:0061458 850 0.110
positive regulation of phosphate metabolic process GO:0045937 56 0.109
heterocycle biosynthetic process GO:0018130 187 0.109
regulation of developmental growth GO:0048638 389 0.108
neurogenesis GO:0022008 236 0.107
Mouse Rat
organelle organization GO:0006996 783 0.105
Mouse
multicellular organism growth GO:0035264 385 0.101
meiotic cell cycle GO:0051321 335 0.099
nucleobase containing compound metabolic process GO:0006139 406 0.098
regulation of growth GO:0040008 409 0.098
negative regulation of biological process GO:0048519 567 0.096
Mouse
vesicle mediated transport GO:0016192 852 0.096
regulation of response to stimulus GO:0048583 243 0.096
Mouse Rat
phosphate containing compound metabolic process GO:0006796 232 0.095
Mouse
developmental growth GO:0048589 412 0.095
nervous system development GO:0007399 253 0.095
Mouse Rat
positive regulation of macromolecule metabolic process GO:0010604 149 0.093
female gamete generation GO:0007292 254 0.093
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.092
Mouse
growth GO:0040007 562 0.092
cell motility GO:0048870 313 0.091
apoptotic process GO:0006915 478 0.091
multi organism reproductive process GO:0044703 867 0.089
regulation of phosphorus metabolic process GO:0051174 81 0.087
axonogenesis GO:0007409 102 0.087
single organism signaling GO:0044700 401 0.087
Mouse Rat
positive regulation of developmental growth GO:0048639 354 0.085
generation of neurons GO:0048699 235 0.085
Mouse Rat
positive regulation of cellular metabolic process GO:0031325 178 0.085
organic substance biosynthetic process GO:1901576 323 0.083
signaling GO:0023052 401 0.083
Mouse Rat
positive regulation of multicellular organism growth GO:0040018 352 0.083
lipid localization GO:0010876 573 0.083
phosphorylation GO:0016310 116 0.082
Mouse
hermaphrodite genitalia development GO:0040035 734 0.079
macromolecule biosynthetic process GO:0009059 250 0.078
biosynthetic process GO:0009058 323 0.078
response to external stimulus GO:0009605 289 0.077
Mouse Rat
regulation of neuron differentiation GO:0045664 40 0.077
Mouse Rat
genitalia development GO:0048806 741 0.076
development of primary sexual characteristics GO:0045137 840 0.076
rna metabolic process GO:0016070 228 0.076
regulation of multicellular organism growth GO:0040014 373 0.074
maintenance of location GO:0051235 580 0.073
cytoskeleton organization GO:0007010 339 0.072
Mouse
regulation of biosynthetic process GO:0009889 189 0.072
cellular response to organic substance GO:0071310 119 0.071
lipid storage GO:0019915 565 0.071
cellular biosynthetic process GO:0044249 315 0.069
rna biosynthetic process GO:0032774 169 0.067
phosphorus metabolic process GO:0006793 232 0.066
Mouse
positive regulation of cell morphogenesis involved in differentiation GO:0010770 4 0.065
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.064
neuron projection development GO:0031175 187 0.064
Mouse Rat
transport GO:0006810 1093 0.059
Mouse
cell division GO:0051301 262 0.058
single organism localization GO:1902578 518 0.058
Mouse
nucleobase containing compound biosynthetic process GO:0034654 184 0.057
positive regulation of signaling GO:0023056 66 0.055
Mouse Rat
transcription dna templated GO:0006351 168 0.053
localization of cell GO:0051674 313 0.053
negative regulation of cellular metabolic process GO:0031324 95 0.053
regulation of primary metabolic process GO:0080090 292 0.052
negative regulation of nematode larval development GO:0061064 208 0.052
phagocytosis engulfment GO:0006911 98 0.052
organelle fission GO:0048285 363 0.052
regulation of nervous system development GO:0051960 41 0.051
Mouse Rat
regulation of cell projection organization GO:0031344 38 0.051
Mouse Rat
regulation of nematode larval development GO:0061062 260 0.050
negative regulation of developmental process GO:0051093 227 0.050
cellular nitrogen compound biosynthetic process GO:0044271 192 0.050
cellular response to chemical stimulus GO:0070887 129 0.049
nucleobase containing compound catabolic process GO:0034655 114 0.049
epithelium development GO:0060429 68 0.049
Mouse
chemotaxis GO:0006935 120 0.048
transcription from rna polymerase ii promoter GO:0006366 149 0.048
positive regulation of metabolic process GO:0009893 187 0.048
regulation of phosphate metabolic process GO:0019220 81 0.048
actin cytoskeleton organization GO:0030036 184 0.045
Mouse
negative regulation of rna metabolic process GO:0051253 53 0.045
regulation of cell communication GO:0010646 176 0.045
Mouse Rat
endocytosis GO:0006897 819 0.044
cell surface receptor signaling pathway GO:0007166 149 0.044
Mouse Rat
regulation of macromolecule metabolic process GO:0060255 421 0.043
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.043
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.043
negative regulation of biosynthetic process GO:0009890 65 0.042
regulation of cellular protein metabolic process GO:0032268 75 0.042
taxis GO:0042330 128 0.042
ribonucleoside triphosphate metabolic process GO:0009199 87 0.042
cellular protein metabolic process GO:0044267 279 0.041
nucleic acid templated transcription GO:0097659 169 0.041
regulation of macromolecule biosynthetic process GO:0010556 189 0.041
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.041
negative regulation of macromolecule metabolic process GO:0010605 229 0.040
organic cyclic compound biosynthetic process GO:1901362 195 0.039
multi organism behavior GO:0051705 389 0.039
Human Mouse
macromolecule modification GO:0043412 218 0.039
positive regulation of cellular process GO:0048522 332 0.039
Mouse Rat
negative regulation of metabolic process GO:0009892 240 0.039
regulation of multicellular organismal development GO:2000026 317 0.039
Mouse Rat
death GO:0016265 547 0.038
oviposition GO:0018991 364 0.038
tissue development GO:0009888 112 0.038
Mouse
regulation of signaling GO:0023051 172 0.038
Mouse Rat
cellular component movement GO:0006928 388 0.038
neuron projection guidance GO:0097485 82 0.037
response to organic substance GO:0010033 131 0.037
vesicle localization GO:0051648 24 0.037
regulation of neuron projection development GO:0010975 31 0.037
Mouse Rat
multi organism reproductive behavior GO:0044705 387 0.037
regulation of cell development GO:0060284 49 0.036
Mouse Rat
cell cycle GO:0007049 526 0.036
positive regulation of cell projection organization GO:0031346 4 0.035
Mouse Rat
negative regulation of gene expression GO:0010629 217 0.035
regulation of transcription dna templated GO:0006355 164 0.035
regulation of cellular biosynthetic process GO:0031326 189 0.035
regulation of gene expression GO:0010468 366 0.035
apoptotic cell clearance GO:0043277 111 0.035
regulation of cell size GO:0008361 30 0.034
cellular localization GO:0051641 360 0.033
Mouse
organelle localization GO:0051640 127 0.033
protein metabolic process GO:0019538 422 0.032
receptor mediated endocytosis GO:0006898 715 0.032
anatomical structure formation involved in morphogenesis GO:0048646 250 0.032
Mouse
negative regulation of vulval development GO:0040027 206 0.032
reproductive behavior GO:0019098 387 0.031
regulation of ras gtpase activity GO:0032318 21 0.031
establishment of organelle localization GO:0051656 123 0.031
purine ribonucleotide catabolic process GO:0009154 75 0.031
collagen and cuticulin based cuticle development GO:0040002 99 0.031
cell projection organization GO:0030030 231 0.030
Mouse Rat
negative regulation of post embryonic development GO:0048581 208 0.030
body morphogenesis GO:0010171 620 0.030
enzyme linked receptor protein signaling pathway GO:0007167 50 0.029
cellular component assembly involved in morphogenesis GO:0010927 183 0.029
microtubule based process GO:0007017 182 0.028
positive regulation of rna metabolic process GO:0051254 103 0.028
mitotic cell cycle process GO:1903047 194 0.028
membrane organization GO:0061024 135 0.028
Mouse
behavior GO:0007610 527 0.028
membrane invagination GO:0010324 98 0.027
negative regulation of cellular biosynthetic process GO:0031327 65 0.027
regulation of protein metabolic process GO:0051246 81 0.027
protein localization GO:0008104 205 0.027
Mouse
ribonucleotide metabolic process GO:0009259 99 0.027
ras protein signal transduction GO:0007265 31 0.027
head development GO:0060322 1 0.026
Mouse Rat
regulation of neurogenesis GO:0050767 40 0.026
Mouse Rat
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.026
macromolecular complex assembly GO:0065003 193 0.026
Rat
macromolecule catabolic process GO:0009057 202 0.026
negative regulation of transcription from rna polymerase ii promoter GO:0000122 45 0.025
gonad development GO:0008406 840 0.025
cellular protein modification process GO:0006464 207 0.025
neuron projection morphogenesis GO:0048812 114 0.025
Mouse
positive regulation of neurogenesis GO:0050769 4 0.025
Mouse Rat
dna metabolic process GO:0006259 74 0.025
establishment of localization in cell GO:0051649 318 0.025
single organism behavior GO:0044708 83 0.025
Human Mouse
regulation of nucleotide catabolic process GO:0030811 35 0.025
striated muscle cell development GO:0055002 157 0.024
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.024
organelle assembly GO:0070925 214 0.024
positive regulation of gtpase activity GO:0043547 28 0.024
homeostatic process GO:0042592 51 0.024
Mouse
muscle cell development GO:0055001 158 0.024
adult behavior GO:0030534 3 0.023
Human Mouse
carboxylic acid transport GO:0046942 15 0.023
meiotic cell cycle process GO:1903046 170 0.023
regulation of rna metabolic process GO:0051252 173 0.022
cell projection morphogenesis GO:0048858 148 0.022
Mouse
catabolic process GO:0009056 318 0.022
positive regulation of nucleotide metabolic process GO:0045981 28 0.022
negative regulation of cellular process GO:0048523 239 0.022
Mouse
small molecule metabolic process GO:0044281 186 0.022
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.022
negative regulation of multicellular organismal process GO:0051241 236 0.022
protein complex subunit organization GO:0071822 280 0.022
Mouse Rat
cell death GO:0008219 547 0.022
phagocytosis GO:0006909 115 0.022
chromosome segregation GO:0007059 180 0.022
regulation of post embryonic development GO:0048580 260 0.022
aromatic compound biosynthetic process GO:0019438 192 0.022
intracellular signal transduction GO:0035556 96 0.022
Mouse
protein modification process GO:0036211 207 0.022
multi multicellular organism process GO:0044706 390 0.022
positive regulation of cellular biosynthetic process GO:0031328 109 0.022
actin filament based process GO:0030029 191 0.021
Mouse
regulation of cellular component organization GO:0051128 248 0.021
Mouse Rat
cellular response to stress GO:0033554 162 0.021
heterocycle catabolic process GO:0046700 119 0.021
positive regulation of nematode larval development GO:0061063 54 0.021
regulation of purine nucleotide catabolic process GO:0033121 35 0.021
response to other organism GO:0051707 101 0.021
oogenesis GO:0048477 229 0.021
organic substance catabolic process GO:1901575 294 0.021
regulation of catabolic process GO:0009894 57 0.020
cytokinesis GO:0000910 80 0.020
cell growth GO:0016049 44 0.020
positive regulation of neuron projection development GO:0010976 4 0.020
Mouse Rat
macromolecular complex subunit organization GO:0043933 320 0.020
Mouse Rat
organophosphate catabolic process GO:0046434 81 0.020
organic substance transport GO:0071702 113 0.020
epithelial tube morphogenesis GO:0060562 1 0.020
Mouse
programmed cell death GO:0012501 500 0.020
establishment of protein localization to membrane GO:0090150 3 0.020
detection of abiotic stimulus GO:0009582 4 0.020
aromatic compound catabolic process GO:0019439 116 0.020
purine nucleoside triphosphate catabolic process GO:0009146 72 0.020
cellular response to nitrogen compound GO:1901699 24 0.020
regulation of cellular component size GO:0032535 40 0.019
regulation of phosphorylation GO:0042325 45 0.019
negative regulation of rna biosynthetic process GO:1902679 53 0.019
ovulation GO:0030728 33 0.019
nucleoside catabolic process GO:0009164 78 0.019
organic cyclic compound catabolic process GO:1901361 119 0.019
response to organonitrogen compound GO:0010243 15 0.019
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.019
nematode male tail tip morphogenesis GO:0045138 77 0.018
pigmentation GO:0043473 2 0.018
axon guidance GO:0007411 82 0.018
neuromuscular junction development GO:0007528 2 0.018
cell morphogenesis GO:0000902 163 0.018
Mouse
positive regulation of phosphorus metabolic process GO:0010562 56 0.018
positive regulation of neuron differentiation GO:0045666 4 0.018
Mouse Rat
positive regulation of catalytic activity GO:0043085 59 0.018
regulation of cell differentiation GO:0045595 81 0.017
Mouse Rat
neuromuscular process GO:0050905 1 0.017
Mouse
protein complex biogenesis GO:0070271 186 0.017
Rat
positive regulation of cellular catabolic process GO:0031331 35 0.017
protein phosphorylation GO:0006468 85 0.017
canonical wnt signaling pathway GO:0060070 3 0.017
bmp signaling pathway GO:0030509 3 0.017
multicellular organismal reproductive behavior GO:0033057 384 0.017
germ cell development GO:0007281 351 0.017
negative regulation of nucleic acid templated transcription GO:1903507 53 0.017
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.016
positive regulation of nucleoside metabolic process GO:0045979 28 0.016
positive regulation of vulval development GO:0040026 52 0.016
regulation of cellular catabolic process GO:0031329 51 0.016
negative regulation of signaling GO:0023057 61 0.016
Mouse
carboxylic acid metabolic process GO:0019752 34 0.016
regulation of intracellular signal transduction GO:1902531 77 0.016
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.016
purine nucleoside triphosphate metabolic process GO:0009144 87 0.015
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.015
regulation of nucleic acid templated transcription GO:1903506 165 0.015
regulation of cell cycle GO:0051726 194 0.015
purine ribonucleoside catabolic process GO:0046130 75 0.015
adult locomotory behavior GO:0008344 1 0.015
cell morphogenesis involved in differentiation GO:0000904 112 0.015
Mouse
regulation of nucleoside metabolic process GO:0009118 37 0.015
myosin filament organization GO:0031033 138 0.015
developmental growth involved in morphogenesis GO:0060560 37 0.014
protein complex assembly GO:0006461 186 0.014
Rat
gtp metabolic process GO:0046039 46 0.014
muscle cell differentiation GO:0042692 171 0.014
regulation of locomotion GO:0040012 161 0.014
purine nucleotide metabolic process GO:0006163 95 0.014
nucleotide catabolic process GO:0009166 77 0.014
regulation of cell division GO:0051302 142 0.014
nucleoside phosphate catabolic process GO:1901292 77 0.013
lipid metabolic process GO:0006629 77 0.013
positive regulation of axon extension GO:0045773 4 0.013
regulation of catalytic activity GO:0050790 78 0.013
small gtpase mediated signal transduction GO:0007264 32 0.013
meiotic nuclear division GO:0007126 300 0.013
cellular catabolic process GO:0044248 199 0.013
ribonucleoside triphosphate catabolic process GO:0009203 72 0.013
organonitrogen compound metabolic process GO:1901564 151 0.013
single organism transport GO:0044765 447 0.013
Mouse
negative regulation of cell morphogenesis involved in differentiation GO:0010771 2 0.013
secretion by cell GO:0032940 138 0.013
cell recognition GO:0008037 85 0.013
regulation of kinase activity GO:0043549 29 0.013
regulation of cell morphogenesis involved in differentiation GO:0010769 29 0.013
Mouse
regulation of cellular localization GO:0060341 42 0.013
purine ribonucleotide metabolic process GO:0009150 95 0.013
pattern specification process GO:0007389 59 0.013
cellular macromolecule localization GO:0070727 75 0.013
Mouse
synaptic vesicle localization GO:0097479 22 0.012
hormone transport GO:0009914 2 0.012
organic acid metabolic process GO:0006082 47 0.012
membrane depolarization GO:0051899 1 0.012
Mouse
cellular macromolecular complex assembly GO:0034622 184 0.012
single organism catabolic process GO:0044712 129 0.012
mapk cascade GO:0000165 31 0.012
Mouse
digestive tract development GO:0048565 122 0.012
response to oxygen containing compound GO:1901700 44 0.012
dendrite development GO:0016358 42 0.012
Mouse Rat
glycosyl compound catabolic process GO:1901658 79 0.012
protein targeting to membrane GO:0006612 1 0.012
positive regulation of molecular function GO:0044093 61 0.012
Mouse
myosin filament assembly GO:0031034 138 0.012
positive regulation of nucleotide catabolic process GO:0030813 28 0.012
regulation of protein ubiquitination GO:0031396 3 0.011
cellular response to nutrient levels GO:0031669 13 0.011
striated muscle myosin thick filament assembly GO:0071688 138 0.011
positive regulation of synapse assembly GO:0051965 1 0.011
organonitrogen compound catabolic process GO:1901565 90 0.011
protein catabolic process GO:0030163 162 0.011
purine containing compound catabolic process GO:0072523 75 0.011
regulation of protein targeting GO:1903533 3 0.011
purine ribonucleoside metabolic process GO:0046128 92 0.011
protein modification by small protein conjugation or removal GO:0070647 40 0.011
response to external biotic stimulus GO:0043207 101 0.011
single organism cellular localization GO:1902580 72 0.011
Mouse
regulation of cellular ketone metabolic process GO:0010565 3 0.010
cell type specific apoptotic process GO:0097285 4 0.010
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 34 0.010
intracellular transport GO:0046907 77 0.010
regulation of canonical wnt signaling pathway GO:0060828 1 0.010
regulation of meiotic cell cycle GO:0051445 136 0.010
sensory organ morphogenesis GO:0090596 2 0.010
cellular nitrogen compound catabolic process GO:0044270 119 0.010
engulfment of apoptotic cell GO:0043652 94 0.010
negative regulation of neuron differentiation GO:0045665 4 0.010
mechanosensory behavior GO:0007638 25 0.010
positive regulation of catabolic process GO:0009896 38 0.010
negative regulation of neurogenesis GO:0050768 4 0.010
carbohydrate derivative catabolic process GO:1901136 82 0.010

shn-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.030
nervous system disease DOID:863 0 0.022
disease of cellular proliferation DOID:14566 0 0.018
cancer DOID:162 0 0.013