Caenorhabditis elegans

159 known processes

bar-1 (CELE_C54D1.6)

Protein BAR-1

bar-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to fibroblast growth factor GO:0071774 5 0.943
Mouse
cell migration GO:0016477 306 0.928
cell morphogenesis GO:0000902 163 0.912
Human Mouse Fly
positive regulation of epithelial cell proliferation GO:0050679 1 0.892
Mouse
cell motility GO:0048870 313 0.883
positive regulation of locomotion GO:0040017 42 0.871
reproductive system development GO:0061458 850 0.869
locomotion GO:0040011 1634 0.863
signaling GO:0023052 401 0.830
mitotic cell cycle process GO:1903047 194 0.821
Worm
localization of cell GO:0051674 313 0.812
neuron projection guidance GO:0097485 82 0.809
specification of axis polarity GO:0065001 13 0.803
Worm
tube morphogenesis GO:0035239 79 0.802
Human Mouse Worm Fly
digestive system development GO:0055123 122 0.798
Mouse Worm Fly
tissue development GO:0009888 112 0.789
neuron development GO:0048666 199 0.783
cell projection organization GO:0030030 231 0.779
regulation of cellular metabolic process GO:0031323 305 0.777
regulation of cell fate commitment GO:0010453 22 0.771
proximal distal pattern formation GO:0009954 6 0.760
Mouse Worm
transcription dna templated GO:0006351 168 0.757
single organism signaling GO:0044700 401 0.752
sex differentiation GO:0007548 909 0.741
cell projection morphogenesis GO:0048858 148 0.732
signal transduction GO:0007165 317 0.731
embryo development GO:0009790 3052 0.728
Zebrafish Mouse Worm Fly
positive regulation of metabolic process GO:0009893 187 0.728
generation of neurons GO:0048699 235 0.724
Mouse Fly
organ development GO:0048513 1102 0.692
immune response GO:0006955 192 0.690
neuron projection development GO:0031175 187 0.686
axon guidance GO:0007411 82 0.678
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.674
tube development GO:0035295 126 0.671
Human Mouse Worm Fly
neurogenesis GO:0022008 236 0.661
Mouse Fly
cell fate commitment involved in formation of primary germ layer GO:0060795 33 0.650
Mouse Worm
regulation of cell morphogenesis GO:0022604 40 0.644
Human Fly
regulation of signal transduction GO:0009966 135 0.636
Zebrafish Mouse
mapk cascade GO:0000165 31 0.631
Mouse
wnt signaling pathway GO:0016055 27 0.626
cellular component movement GO:0006928 388 0.611
nucleic acid metabolic process GO:0090304 299 0.608
positive regulation of stem cell differentiation GO:2000738 1 0.604
Human
regulation of mapk cascade GO:0043408 23 0.603
Mouse
regulation of cell fate specification GO:0042659 22 0.601
gamete generation GO:0007276 461 0.595
Mouse Fly
positive regulation of biosynthetic process GO:0009891 109 0.588
reproductive structure development GO:0048608 850 0.586
positive regulation of transcription dna templated GO:0045893 102 0.583
positive regulation of multicellular organismal process GO:0051240 417 0.582
positive regulation of neurogenesis GO:0050769 4 0.572
Mouse
gastrulation GO:0007369 58 0.567
Mouse Worm Fly
regulation of rna biosynthetic process GO:2001141 165 0.566
positive regulation of rna biosynthetic process GO:1902680 102 0.562
response to chemical GO:0042221 356 0.559
Human Mouse
tissue morphogenesis GO:0048729 65 0.558
head development GO:0060322 1 0.557
Mouse
digestive tract development GO:0048565 122 0.549
Mouse Worm Fly
positive regulation of gene expression GO:0010628 112 0.543
single organism localization GO:1902578 518 0.542
Human Mouse Fly
single organism organelle organization GO:1902589 501 0.541
Human Mouse Worm
nucleic acid templated transcription GO:0097659 169 0.541
regulation of nucleic acid templated transcription GO:1903506 165 0.538
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.533
embryo development ending in birth or egg hatching GO:0009792 2992 0.533
Mouse Worm Fly
nervous system development GO:0007399 253 0.527
Mouse Fly
axon development GO:0061564 163 0.523
regulation of response to stimulus GO:0048583 243 0.522
Zebrafish Mouse
digestive tract morphogenesis GO:0048546 76 0.520
Mouse Worm Fly
epithelium development GO:0060429 68 0.516
rna biosynthetic process GO:0032774 169 0.515
sensory organ morphogenesis GO:0090596 2 0.513
Mouse Fly
pattern specification process GO:0007389 59 0.512
Zebrafish Mouse Worm Fly
anatomical structure formation involved in morphogenesis GO:0048646 250 0.510
Mouse Worm Fly
post embryonic development GO:0009791 2152 0.510
female gamete generation GO:0007292 254 0.501
Mouse Fly
cell fate commitment GO:0045165 139 0.498
regulation of transcription dna templated GO:0006355 164 0.495
axonogenesis GO:0007409 102 0.491
positive regulation of cellular process GO:0048522 332 0.488
regulation of cell migration GO:0030334 55 0.483
cell part morphogenesis GO:0032990 152 0.477
intracellular signal transduction GO:0035556 96 0.475
positive regulation of cellular biosynthetic process GO:0031328 109 0.473
cell development GO:0048468 696 0.470
Human Mouse Fly
cell cycle GO:0007049 526 0.460
Human Mouse Worm
epithelial cell proliferation GO:0050673 1 0.458
Mouse
enzyme linked receptor protein signaling pathway GO:0007167 50 0.453
Mouse
negative regulation of cellular process GO:0048523 239 0.452
Human Zebrafish Mouse Fly
developmental process involved in reproduction GO:0003006 1165 0.451
regulation of cellular component organization GO:0051128 248 0.444
Human Mouse Worm Fly
genitalia development GO:0048806 741 0.443
positive regulation of cell communication GO:0010647 69 0.433
Mouse
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.431
organelle organization GO:0006996 783 0.428
Human Mouse Worm
chromosome organization GO:0051276 104 0.426
Human Mouse
gonad development GO:0008406 840 0.426
regulation of intracellular signal transduction GO:1902531 77 0.424
Mouse
regulation of metabolic process GO:0019222 478 0.422
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.411
neuron projection morphogenesis GO:0048812 114 0.411
regulation of developmental process GO:0050793 684 0.410
cellular response to organic substance GO:0071310 119 0.407
Human Mouse
positive regulation of nematode larval development GO:0061063 54 0.405
regulation of macromolecule biosynthetic process GO:0010556 189 0.405
regulation of cell cycle process GO:0010564 145 0.402
Human Mouse
taxis GO:0042330 128 0.402
behavior GO:0007610 527 0.399
regulation of programmed cell death GO:0043067 50 0.393
Human Mouse
chemotaxis GO:0006935 120 0.391
regulation of macromolecule metabolic process GO:0060255 421 0.381
response to wounding GO:0009611 4 0.381
embryonic morphogenesis GO:0048598 152 0.381
Mouse Worm Fly
transport GO:0006810 1093 0.377
cellular component morphogenesis GO:0032989 318 0.376
Human Mouse Fly
regulation of mitotic cell cycle GO:0007346 76 0.370
Mouse
positive regulation of mapk cascade GO:0043410 14 0.369
Mouse
regulation of cellular component size GO:0032535 40 0.369
single organism reproductive process GO:0044702 1196 0.368
development of primary sexual characteristics GO:0045137 840 0.365
developmental growth GO:0048589 412 0.352
Fly
cell surface receptor signaling pathway GO:0007166 149 0.352
regulation of cell motility GO:2000145 57 0.351
regulation of epithelial cell proliferation GO:0050678 1 0.349
Mouse
single organism transport GO:0044765 447 0.347
Human Mouse
positive regulation of signal transduction GO:0009967 40 0.342
Mouse
regulation of nitrogen compound metabolic process GO:0051171 222 0.341
regulation of primary metabolic process GO:0080090 292 0.337
aromatic compound biosynthetic process GO:0019438 192 0.335
neuron differentiation GO:0030182 217 0.334
Fly
regulation of multicellular organismal development GO:2000026 317 0.332
multicellular organism reproduction GO:0032504 819 0.332
sexual reproduction GO:0019953 546 0.330
organic substance catabolic process GO:1901575 294 0.329
cell cycle process GO:0022402 482 0.329
Human Mouse Worm
positive regulation of intracellular signal transduction GO:1902533 24 0.325
Mouse
multi organism reproductive process GO:0044703 867 0.322
regulation of biosynthetic process GO:0009889 189 0.321
positive regulation of developmental process GO:0051094 408 0.318
mesoderm morphogenesis GO:0048332 24 0.317
multicellular organismal reproductive behavior GO:0033057 384 0.312
regulation of anatomical structure morphogenesis GO:0022603 51 0.311
Human Mouse Fly
establishment of localization GO:0051234 1171 0.310
positive regulation of cellular metabolic process GO:0031325 178 0.310
regulation of cell cycle GO:0051726 194 0.309
Human Mouse
regulation of multicellular organismal process GO:0051239 726 0.304
organ morphogenesis GO:0009887 67 0.299
Mouse Fly
regulation of phosphorus metabolic process GO:0051174 81 0.298
Mouse Worm
synaptic transmission GO:0007268 106 0.298
Mouse
reproductive behavior GO:0019098 387 0.296
mesoderm development GO:0007498 27 0.293
negative regulation of biological process GO:0048519 567 0.292
Human Zebrafish Mouse Worm Fly
positive regulation of cell cycle GO:0045787 55 0.290
regulation of cell division GO:0051302 142 0.289
oogenesis GO:0048477 229 0.288
Mouse Fly
muscle tissue development GO:0060537 1 0.288
response to endogenous stimulus GO:0009719 33 0.287
Human Mouse
transmembrane transport GO:0055085 110 0.285
Human
regulation of locomotion GO:0040012 161 0.284
positive regulation of phosphate metabolic process GO:0045937 56 0.283
Mouse Worm
single organism catabolic process GO:0044712 129 0.282
regulation of molecular function GO:0065009 89 0.282
Human Mouse Worm
positive regulation of organ growth GO:0046622 4 0.280
response to organic substance GO:0010033 131 0.276
Human Mouse
positive regulation of cell migration GO:0030335 3 0.275
positive regulation of rna metabolic process GO:0051254 103 0.267
cell death GO:0008219 547 0.266
Human Mouse Fly
rna metabolic process GO:0016070 228 0.265
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.265
protein catabolic process GO:0030163 162 0.263
positive regulation of neuron differentiation GO:0045666 4 0.262
regionalization GO:0003002 31 0.262
Zebrafish Mouse Worm Fly
positive regulation of phosphorylation GO:0042327 27 0.262
Mouse Worm
regulation of signaling GO:0023051 172 0.256
Zebrafish Mouse Fly
mitotic nuclear division GO:0007067 89 0.254
negative regulation of transcription from rna polymerase ii promoter GO:0000122 45 0.254
Mouse
ion transport GO:0006811 113 0.253
Human
positive regulation of macromolecule metabolic process GO:0010604 149 0.250
cell morphogenesis involved in differentiation GO:0000904 112 0.247
Human Mouse
negative regulation of multicellular organismal process GO:0051241 236 0.247
Zebrafish Mouse Fly
regulation of development heterochronic GO:0040034 18 0.247
positive regulation of molecular function GO:0044093 61 0.242
Human Mouse Worm
death GO:0016265 547 0.241
Human Mouse Fly
positive regulation of signaling GO:0023056 66 0.238
Mouse
protein phosphorylation GO:0006468 85 0.237
Worm
developmental induction GO:0031128 1 0.234
Mouse Fly
organic cyclic compound biosynthetic process GO:1901362 195 0.232
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.229
negative regulation of gene expression GO:0010629 217 0.229
Human Mouse
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 5 0.228
response to external stimulus GO:0009605 289 0.228
Human
system process GO:0003008 136 0.227
Human Fly
catabolic process GO:0009056 318 0.226
regulation of vulval development GO:0040028 248 0.226
gene expression GO:0010467 412 0.224
mesodermal cell differentiation GO:0048333 15 0.223
cell division GO:0051301 262 0.220
positive regulation of cell projection organization GO:0031346 4 0.219
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.218
cellular response to chemical stimulus GO:0070887 129 0.215
Human Mouse
regulation of nematode larval development GO:0061062 260 0.215
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.212
phosphorus metabolic process GO:0006793 232 0.211
Mouse Worm
apoptotic process GO:0006915 478 0.210
Human Mouse
regeneration GO:0031099 4 0.209
signal transduction by phosphorylation GO:0023014 31 0.208
Mouse
positive regulation of transferase activity GO:0051347 21 0.208
Mouse Worm
cellular nitrogen compound biosynthetic process GO:0044271 192 0.208
positive regulation of vulval development GO:0040026 52 0.206
cation transport GO:0006812 78 0.204
Human
homeostatic process GO:0042592 51 0.204
Mouse
chromosome segregation GO:0007059 180 0.201
Human Mouse
growth GO:0040007 562 0.201
Fly
neural precursor cell proliferation GO:0061351 9 0.199
Mouse
regulation of localization GO:0032879 194 0.198
regulation of gene expression GO:0010468 366 0.198
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.192
protein metabolic process GO:0019538 422 0.191
Human Worm
negative regulation of cell communication GO:0010648 61 0.191
Zebrafish Mouse Fly
positive regulation of phosphorus metabolic process GO:0010562 56 0.185
Mouse Worm
innate immune response GO:0045087 190 0.185
regulation of neurogenesis GO:0050767 40 0.185
Mouse
skeletal muscle organ development GO:0060538 3 0.184
biosynthetic process GO:0009058 323 0.184
regulation of phosphorylation GO:0042325 45 0.183
Mouse Worm
positive regulation of catabolic process GO:0009896 38 0.182
multi organism reproductive behavior GO:0044705 387 0.181
regulation of mesoderm development GO:2000380 2 0.179
metal ion transport GO:0030001 49 0.178
Human
cellular response to growth factor stimulus GO:0071363 18 0.176
Human Mouse
muscle structure development GO:0061061 191 0.175
Mouse
negative regulation of metabolic process GO:0009892 240 0.173
Human Mouse
regulation of organ growth GO:0046620 5 0.173
post embryonic organ development GO:0048569 336 0.170
fibroblast growth factor receptor signaling pathway GO:0008543 5 0.168
Mouse
hermaphrodite genitalia development GO:0040035 734 0.168
organelle fission GO:0048285 363 0.166
rho protein signal transduction GO:0007266 2 0.165
cell proliferation GO:0008283 116 0.165
Human Mouse Fly
lipid biosynthetic process GO:0008610 28 0.165
positive regulation of response to stimulus GO:0048584 55 0.163
Mouse
body morphogenesis GO:0010171 620 0.163
Worm
oviposition GO:0018991 364 0.161
response to other organism GO:0051707 101 0.161
regulation of cellular component movement GO:0051270 62 0.160
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 34 0.160
Mouse
transcription from rna polymerase ii promoter GO:0006366 149 0.159
phagocytosis GO:0006909 115 0.157
negative regulation of rna biosynthetic process GO:1902679 53 0.155
Human Mouse
multicellular organism growth GO:0035264 385 0.154
negative regulation of wnt signaling pathway GO:0030178 6 0.153
Zebrafish
anterior posterior pattern specification GO:0009952 27 0.151
Mouse
regulation of organelle organization GO:0033043 164 0.151
Human Mouse Worm
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.150
Mouse Fly
negative regulation of signal transduction GO:0009968 60 0.149
Zebrafish Mouse
protein localization GO:0008104 205 0.149
Human Mouse Worm Fly
macromolecule biosynthetic process GO:0009059 250 0.148
nucleobase containing compound metabolic process GO:0006139 406 0.148
regulation of cell size GO:0008361 30 0.146
positive regulation of jnk cascade GO:0046330 3 0.146
regulation of biological quality GO:0065008 741 0.145
Human Mouse Fly
positive regulation of cell differentiation GO:0045597 8 0.145
Human Mouse
muscle organ development GO:0007517 26 0.144
regulation of rna metabolic process GO:0051252 173 0.143
cellular localization GO:0051641 360 0.142
Human Mouse Fly
regulation of gastrulation GO:0010470 4 0.135
regulation of nuclear division GO:0051783 115 0.134
vulval development GO:0040025 333 0.133
negative regulation of transcription dna templated GO:0045892 53 0.133
Human Mouse
regulation of cell communication GO:0010646 176 0.133
Zebrafish Mouse Fly
cellular component biogenesis GO:0044085 297 0.132
Human Mouse Fly
regulation of protein serine threonine kinase activity GO:0071900 18 0.131
cellular catabolic process GO:0044248 199 0.131
positive regulation of growth GO:0045927 369 0.130
multi organism behavior GO:0051705 389 0.129
organic substance biosynthetic process GO:1901576 323 0.129
nucleobase containing compound biosynthetic process GO:0034654 184 0.129
adult behavior GO:0030534 3 0.129
cellular response to hormone stimulus GO:0032870 14 0.127
epithelial tube morphogenesis GO:0060562 1 0.126
Human Mouse Fly
phosphate containing compound metabolic process GO:0006796 232 0.126
Mouse Worm
negative regulation of macromolecule metabolic process GO:0010605 229 0.125
Human Mouse
regulation of cell death GO:0010941 65 0.125
Human Mouse
positive regulation of nucleic acid templated transcription GO:1903508 102 0.125
regulation of developmental growth GO:0048638 389 0.124
regulation of phosphate metabolic process GO:0019220 81 0.124
Mouse Worm
germ cell development GO:0007281 351 0.121
Mouse Fly
regulation of protein catabolic process GO:0042176 13 0.118
regulation of cell proliferation GO:0042127 105 0.118
Human Mouse
positive regulation of protein kinase activity GO:0045860 18 0.117
Worm
regulation of catalytic activity GO:0050790 78 0.116
Mouse Worm
regulation of apoptotic process GO:0042981 36 0.115
Human Mouse
defense response GO:0006952 296 0.115
macromolecular complex subunit organization GO:0043933 320 0.115
Worm
regulation of growth GO:0040008 409 0.114
regulation of neuron differentiation GO:0045664 40 0.114
negative regulation of developmental process GO:0051093 227 0.113
Zebrafish Mouse Fly
macromolecule catabolic process GO:0009057 202 0.113
endocytosis GO:0006897 819 0.112
divalent inorganic cation transport GO:0072511 17 0.111
Human
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.111
Human Mouse
negative regulation of response to stimulus GO:0048585 73 0.109
Zebrafish Mouse
negative regulation of signaling GO:0023057 61 0.109
Zebrafish Mouse Fly
multi multicellular organism process GO:0044706 390 0.108
regulation of cellular biosynthetic process GO:0031326 189 0.108
neuron recognition GO:0008038 83 0.107
positive regulation of neuron projection development GO:0010976 4 0.107
heterocycle biosynthetic process GO:0018130 187 0.107
cellular component assembly GO:0022607 293 0.103
Human Mouse Fly
ras protein signal transduction GO:0007265 31 0.102
regulation of lipid metabolic process GO:0019216 4 0.102
regulation of feeding behavior GO:0060259 38 0.102
positive regulation of catalytic activity GO:0043085 59 0.100
Mouse Worm
epidermis morphogenesis GO:0048730 7 0.100
Mouse
determination of adult lifespan GO:0008340 812 0.099
cellular macromolecule biosynthetic process GO:0034645 247 0.099
lipid metabolic process GO:0006629 77 0.098
cytoskeleton organization GO:0007010 339 0.098
Human Worm
striated muscle cell differentiation GO:0051146 158 0.097
mesodermal cell fate specification GO:0007501 13 0.097
cellular response to endogenous stimulus GO:0071495 32 0.097
Human Mouse
positive regulation of developmental growth GO:0048639 354 0.096
proximal distal axis specification GO:0009946 6 0.095
Worm
aging GO:0007568 812 0.095
negative regulation of cell death GO:0060548 21 0.093
Human Mouse
cellular biosynthetic process GO:0044249 315 0.092
multicellular organismal reproductive process GO:0048609 815 0.092
regulation of organ morphogenesis GO:2000027 4 0.091
Mouse Fly
regulation of multicellular organism growth GO:0040014 373 0.089
regulation of axon extension GO:0030516 20 0.089
establishment of localization in cell GO:0051649 318 0.089
Human Mouse
response to abiotic stimulus GO:0009628 152 0.089
Human
regulation of cell shape GO:0008360 6 0.089
Fly
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.087
Human Mouse
regulation of lipid biosynthetic process GO:0046890 1 0.087
dna metabolic process GO:0006259 74 0.087
Mouse
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.086
Human Mouse
negative regulation of programmed cell death GO:0043069 19 0.086
Human Mouse
regulation of cell differentiation GO:0045595 81 0.086
negative regulation of vulval development GO:0040027 206 0.086
regulation of stem cell differentiation GO:2000736 1 0.086
Human Fly
regulation of kinase activity GO:0043549 29 0.085
Worm
regulation of synaptic transmission GO:0050804 34 0.085
multicellular organismal aging GO:0010259 812 0.084
phosphorylation GO:0016310 116 0.084
Mouse Worm
small molecule metabolic process GO:0044281 186 0.084
Human
neurological system process GO:0050877 53 0.083
Fly
macromolecule localization GO:0033036 771 0.083
Human Mouse Worm Fly
anatomical structure homeostasis GO:0060249 11 0.082
Mouse
regulation of map kinase activity GO:0043405 13 0.082
negative regulation of cellular metabolic process GO:0031324 95 0.082
Human Mouse
lipid localization GO:0010876 573 0.082
regulation of wnt signaling pathway GO:0030111 9 0.082
Zebrafish
glycosyl compound metabolic process GO:1901657 100 0.080
positive regulation of cell morphogenesis involved in differentiation GO:0010770 4 0.080
Human
positive regulation of cell development GO:0010720 6 0.080
Human Mouse
negative regulation of apoptotic process GO:0043066 17 0.079
Human Mouse
organ growth GO:0035265 5 0.078
cellular protein modification process GO:0006464 207 0.076
Human Worm
regulation of catabolic process GO:0009894 57 0.076
negative regulation of nucleic acid templated transcription GO:1903507 53 0.076
Human Mouse
cellular lipid metabolic process GO:0044255 40 0.076
embryonic pattern specification GO:0009880 21 0.075
Zebrafish Mouse
maintenance of location GO:0051235 580 0.075
regulation of behavior GO:0050795 97 0.075
programmed cell death GO:0012501 500 0.074
Human Mouse Fly
regulation of apoptotic signaling pathway GO:2001233 1 0.073
Mouse
proteolysis GO:0006508 61 0.073
membrane organization GO:0061024 135 0.072
Human Fly
cell growth GO:0016049 44 0.072
endodermal cell differentiation GO:0035987 18 0.071
Mouse Worm
molting cycle GO:0042303 281 0.071
Mouse Fly
activation of protein kinase activity GO:0032147 11 0.071
muscle cell differentiation GO:0042692 171 0.070
Mouse
stem cell differentiation GO:0048863 7 0.070
Human Fly
negative regulation of post embryonic development GO:0048581 208 0.069
regulation of cell morphogenesis involved in differentiation GO:0010769 29 0.069
Human
protein complex subunit organization GO:0071822 280 0.069
Worm
negative regulation of cell morphogenesis involved in differentiation GO:0010771 2 0.069
macromolecule modification GO:0043412 218 0.068
Human Worm
regulation of neurotransmitter levels GO:0001505 36 0.067
positive regulation of cell death GO:0010942 38 0.066
Human
response to growth factor GO:0070848 18 0.065
Human Mouse
cellular response to stress GO:0033554 162 0.065
regulation of transport GO:0051049 91 0.064
Human
positive regulation of kinase activity GO:0033674 19 0.064
Worm
regulation of protein metabolic process GO:0051246 81 0.064
Human Worm
lipid storage GO:0019915 565 0.064
cell type specific apoptotic process GO:0097285 4 0.062
oocyte differentiation GO:0009994 45 0.062
Mouse
negative regulation of neurogenesis GO:0050768 4 0.062
Mouse
epithelial cell differentiation GO:0030855 17 0.061
Mouse
regulation of canonical wnt signaling pathway GO:0060828 1 0.061
regulation of cytoplasmic transport GO:1903649 3 0.061
Human
regulation of cell development GO:0060284 49 0.061
Human Mouse
single organism intracellular transport GO:1902582 70 0.061
Human
cell recognition GO:0008037 85 0.061
epidermis development GO:0008544 24 0.060
Mouse
regulation of protein kinase activity GO:0045859 28 0.059
Worm
axis specification GO:0009798 23 0.059
Zebrafish Mouse Worm
regulation of cell projection organization GO:0031344 38 0.059
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.059
regulation of cellular catabolic process GO:0031329 51 0.059
regulation of post embryonic development GO:0048580 260 0.058
filopodium assembly GO:0046847 2 0.058
single organism nuclear import GO:1902593 6 0.057
Human
response to mechanical stimulus GO:0009612 28 0.057
Human
memory GO:0007613 3 0.057
Fly
positive regulation of stress activated mapk cascade GO:0032874 3 0.056
cation transmembrane transport GO:0098655 59 0.056
regulation of neuron projection development GO:0010975 31 0.056
single organism behavior GO:0044708 83 0.056
Fly
meiotic cell cycle GO:0051321 335 0.055
response to biotic stimulus GO:0009607 101 0.055
negative regulation of rna metabolic process GO:0051253 53 0.054
Human Mouse
developmental growth involved in morphogenesis GO:0060560 37 0.053
Fly
endoderm development GO:0007492 20 0.052
Mouse Worm
developmental cell growth GO:0048588 39 0.052
meiotic nuclear division GO:0007126 300 0.052
actin filament based process GO:0030029 191 0.052
Worm
skin development GO:0043588 24 0.051
Mouse
organonitrogen compound metabolic process GO:1901564 151 0.050
determination of left right symmetry GO:0007368 9 0.050
regulation of axonogenesis GO:0050770 24 0.049
secretion by cell GO:0032940 138 0.049
dauer larval development GO:0040024 92 0.049
negative regulation of bmp signaling pathway GO:0030514 1 0.048
oxoacid metabolic process GO:0043436 47 0.047
Human
positive regulation of multicellular organism growth GO:0040018 352 0.047
protein import into nucleus GO:0006606 6 0.047
Human
cell projection assembly GO:0030031 35 0.047
intracellular transport GO:0046907 77 0.047
Human
development of primary male sexual characteristics GO:0046546 4 0.047
endodermal cell fate determination GO:0007493 2 0.046
regulation of anatomical structure size GO:0090066 46 0.045
sister chromatid segregation GO:0000819 46 0.045
positive regulation of map kinase activity GO:0043406 9 0.045
defense response to other organism GO:0098542 100 0.045
response to external biotic stimulus GO:0043207 101 0.045
regulation of microtubule cytoskeleton organization GO:0070507 21 0.045
Human
locomotory behavior GO:0007626 40 0.044
regulation of system process GO:0044057 27 0.044
Human
regulation of meiotic cell cycle GO:0051445 136 0.044
mitotic spindle organization GO:0007052 81 0.043
Worm
regulation of mitosis GO:0007088 18 0.043
vesicle mediated transport GO:0016192 852 0.043
learning or memory GO:0007611 27 0.043
Fly
protein complex biogenesis GO:0070271 186 0.043
chemical homeostasis GO:0048878 29 0.042
regulation of hydrolase activity GO:0051336 45 0.042
cellular response to abiotic stimulus GO:0071214 4 0.042
phagocytosis engulfment GO:0006911 98 0.041
carbohydrate derivative metabolic process GO:1901135 141 0.041
Human
regulation of nucleocytoplasmic transport GO:0046822 3 0.041
Human
positive regulation of apoptotic process GO:0043065 17 0.041
Human
ion transmembrane transport GO:0034220 91 0.041
Human
g protein coupled receptor signaling pathway GO:0007186 46 0.040
positive regulation of hydrolase activity GO:0051345 38 0.040
protein modification process GO:0036211 207 0.040
Human Worm
organic substance transport GO:0071702 113 0.039
Human
posttranscriptional regulation of gene expression GO:0010608 166 0.039
regulation of nervous system development GO:0051960 41 0.039
Mouse
neuron fate commitment GO:0048663 8 0.039
regulation of cellular ketone metabolic process GO:0010565 3 0.039
regulation of transferase activity GO:0051338 31 0.039
Mouse Worm
positive regulation of programmed cell death GO:0043068 27 0.039
Human
protein complex assembly GO:0006461 186 0.039
cellular protein metabolic process GO:0044267 279 0.038
Human Worm
regulation of meiosis GO:0040020 94 0.038
negative regulation of cellular biosynthetic process GO:0031327 65 0.037
Human Mouse
negative regulation of nematode larval development GO:0061064 208 0.037
oocyte construction GO:0007308 2 0.037
response to acid chemical GO:0001101 4 0.037
response to oxygen containing compound GO:1901700 44 0.036
Human
adult locomotory behavior GO:0008344 1 0.036
regulation of cellular protein metabolic process GO:0032268 75 0.036
Human Worm
regulation of protein import into nucleus GO:0042306 3 0.036
Human
negative regulation of biosynthetic process GO:0009890 65 0.036
Human Mouse
positive regulation of ras protein signal transduction GO:0046579 7 0.036
calcium ion transmembrane transport GO:0070588 13 0.036
cognition GO:0050890 27 0.035
Fly
positive regulation of small gtpase mediated signal transduction GO:0051057 7 0.035
male sex differentiation GO:0046661 86 0.035
Mouse
mitotic sister chromatid segregation GO:0000070 38 0.035
regulation of cellular response to growth factor stimulus GO:0090287 11 0.035
Mouse
steroid biosynthetic process GO:0006694 2 0.034
ribonucleotide catabolic process GO:0009261 75 0.034
organophosphate metabolic process GO:0019637 125 0.034
divalent metal ion transport GO:0070838 17 0.033
Human
regulation of bmp signaling pathway GO:0030510 3 0.033
cell cell signaling GO:0007267 118 0.033
Mouse Fly
spindle organization GO:0007051 92 0.033
Worm
muscle system process GO:0003012 43 0.032

bar-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.194
Human
disease of anatomical entity DOID:7 0 0.113
Human
cancer DOID:162 0 0.087
Human
cardiovascular system disease DOID:1287 0 0.067
Human
musculoskeletal system disease DOID:17 0 0.043
Human