Caenorhabditis elegans

15 known processes

his-4 (CELE_T10C6.11)

Protein HIS-4

his-4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
gonad development GO:0008406 840 0.797
Worm
sex differentiation GO:0007548 909 0.779
Worm
development of primary sexual characteristics GO:0045137 840 0.778
Worm
post embryonic development GO:0009791 2152 0.772
hermaphrodite genitalia development GO:0040035 734 0.753
Worm
chromatin assembly or disassembly GO:0006333 1 0.737
reproductive structure development GO:0048608 850 0.725
Worm
genitalia development GO:0048806 741 0.712
Worm
organ development GO:0048513 1102 0.666
Worm
embryo development GO:0009790 3052 0.644
multicellular organismal reproductive behavior GO:0033057 384 0.622
Worm
developmental process involved in reproduction GO:0003006 1165 0.621
Worm
embryo development ending in birth or egg hatching GO:0009792 2992 0.616
reproductive system development GO:0061458 850 0.616
Worm
innate immune response GO:0045087 190 0.615
Worm
locomotion GO:0040011 1634 0.593
multicellular organism reproduction GO:0032504 819 0.508
Worm
tube development GO:0035295 126 0.497
Worm
single organism reproductive process GO:0044702 1196 0.455
Worm
immune response GO:0006955 192 0.428
Worm
behavior GO:0007610 527 0.401
Worm
oviposition GO:0018991 364 0.392
Worm
multicellular organismal reproductive process GO:0048609 815 0.386
Worm
digestive system development GO:0055123 122 0.380
Worm
regulation of transcription dna templated GO:0006355 164 0.377
multi multicellular organism process GO:0044706 390 0.359
Worm
organelle organization GO:0006996 783 0.339
pharynx development GO:0060465 51 0.324
Worm
multi organism reproductive behavior GO:0044705 387 0.321
Worm
reproductive behavior GO:0019098 387 0.313
Worm
digestive tract development GO:0048565 122 0.312
Worm
meiotic cell cycle GO:0051321 335 0.303
multi organism reproductive process GO:0044703 867 0.299
Worm
chromosome organization GO:0051276 104 0.297
meiotic cell cycle process GO:1903046 170 0.296
defense response GO:0006952 296 0.287
Worm
sexual reproduction GO:0019953 546 0.283
cellular macromolecule biosynthetic process GO:0034645 247 0.272
macromolecular complex subunit organization GO:0043933 320 0.252
multi organism behavior GO:0051705 389 0.247
Worm
organic substance biosynthetic process GO:1901576 323 0.232
regulation of macromolecule metabolic process GO:0060255 421 0.230
rna biosynthetic process GO:0032774 169 0.224
regulation of rna biosynthetic process GO:2001141 165 0.223
regulation of cellular biosynthetic process GO:0031326 189 0.215
regulation of metabolic process GO:0019222 478 0.211
negative regulation of biosynthetic process GO:0009890 65 0.209
nucleobase containing compound metabolic process GO:0006139 406 0.205
macromolecule biosynthetic process GO:0009059 250 0.202
negative regulation of biological process GO:0048519 567 0.197
negative regulation of metabolic process GO:0009892 240 0.193
regulation of nitrogen compound metabolic process GO:0051171 222 0.191
biosynthetic process GO:0009058 323 0.183
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.181
dna metabolic process GO:0006259 74 0.177
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.171
regulation of gene expression GO:0010468 366 0.170
gene expression GO:0010467 412 0.170
transcription from rna polymerase ii promoter GO:0006366 149 0.166
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.166
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.154
transcription dna templated GO:0006351 168 0.151
regulation of cellular metabolic process GO:0031323 305 0.148
regulation of macromolecule biosynthetic process GO:0010556 189 0.147
cellular response to dna damage stimulus GO:0006974 41 0.144
cellular response to stress GO:0033554 162 0.134
regulation of biosynthetic process GO:0009889 189 0.134
regulation of rna metabolic process GO:0051252 173 0.132
nucleic acid metabolic process GO:0090304 299 0.130
cellular nitrogen compound biosynthetic process GO:0044271 192 0.129
negative regulation of macromolecule metabolic process GO:0010605 229 0.128
negative regulation of cellular biosynthetic process GO:0031327 65 0.125
negative regulation of gene expression GO:0010629 217 0.124
gene silencing GO:0016458 143 0.121
negative regulation of transcription from rna polymerase ii promoter GO:0000122 45 0.118
nucleic acid templated transcription GO:0097659 169 0.117
cell death GO:0008219 547 0.116
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.114
aromatic compound biosynthetic process GO:0019438 192 0.113
apoptotic process GO:0006915 478 0.112
regulation of nucleic acid templated transcription GO:1903506 165 0.110
negative regulation of transcription dna templated GO:0045892 53 0.108
organic cyclic compound biosynthetic process GO:1901362 195 0.107
nucleobase containing compound biosynthetic process GO:0034654 184 0.107
aging GO:0007568 812 0.106
rna metabolic process GO:0016070 228 0.102
regulation of primary metabolic process GO:0080090 292 0.099
multicellular organismal aging GO:0010259 812 0.088
negative regulation of cellular process GO:0048523 239 0.087
determination of adult lifespan GO:0008340 812 0.087
receptor mediated endocytosis GO:0006898 715 0.083
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.083
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.082
vesicle mediated transport GO:0016192 852 0.081
establishment of localization GO:0051234 1171 0.081
regulation of multicellular organismal process GO:0051239 726 0.079
germ cell development GO:0007281 351 0.077
cellular biosynthetic process GO:0044249 315 0.076
macromolecule localization GO:0033036 771 0.075
heterocycle biosynthetic process GO:0018130 187 0.075
negative regulation of nucleic acid templated transcription GO:1903507 53 0.075
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.073
cell development GO:0048468 696 0.072
regulation of biological quality GO:0065008 741 0.071
dna repair GO:0006281 23 0.071
transport GO:0006810 1093 0.065
lipid localization GO:0010876 573 0.065
lipid storage GO:0019915 565 0.065
maintenance of location GO:0051235 580 0.064
single organism localization GO:1902578 518 0.064
gamete generation GO:0007276 461 0.064
negative regulation of cellular metabolic process GO:0031324 95 0.064
death GO:0016265 547 0.062
endocytosis GO:0006897 819 0.061
chromatin organization GO:0006325 32 0.058
negative regulation of rna biosynthetic process GO:1902679 53 0.057
negative regulation of rna metabolic process GO:0051253 53 0.056
body morphogenesis GO:0010171 620 0.056
cellular component assembly involved in morphogenesis GO:0010927 183 0.055
programmed cell death GO:0012501 500 0.052
fertilization GO:0009566 63 0.048
cell cycle GO:0007049 526 0.046
vulval development GO:0040025 333 0.045
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.044
single organism transport GO:0044765 447 0.044
anatomical structure formation involved in morphogenesis GO:0048646 250 0.042
cellular protein complex assembly GO:0043623 178 0.042
female gamete generation GO:0007292 254 0.041
organelle assembly GO:0070925 214 0.040
oogenesis GO:0048477 229 0.039
muscle cell differentiation GO:0042692 171 0.038
single organism organelle organization GO:1902589 501 0.038
protein metabolic process GO:0019538 422 0.037
protein complex assembly GO:0006461 186 0.037
cellular localization GO:0051641 360 0.037
molting cycle GO:0042303 281 0.036
muscle structure development GO:0061061 191 0.036
cellular protein modification process GO:0006464 207 0.035
protein complex subunit organization GO:0071822 280 0.034
meiotic chromosome segregation GO:0045132 139 0.034
cell motility GO:0048870 313 0.034
inductive cell migration GO:0040039 145 0.033
cellular component biogenesis GO:0044085 297 0.033
positive regulation of cellular process GO:0048522 332 0.031
multicellular organism growth GO:0035264 385 0.031
single fertilization GO:0007338 61 0.031
organelle fission GO:0048285 363 0.030
myofibril assembly GO:0030239 154 0.030
actin cytoskeleton organization GO:0030036 184 0.029
cytoskeleton organization GO:0007010 339 0.029
regulation of developmental process GO:0050793 684 0.029
regulation of vulval development GO:0040028 248 0.029
regulation of gene expression epigenetic GO:0040029 163 0.028
negative regulation of nematode larval development GO:0061064 208 0.028
cellular component assembly GO:0022607 293 0.027
positive regulation of developmental growth GO:0048639 354 0.027
cellular macromolecular complex assembly GO:0034622 184 0.027
regulation of multicellular organism growth GO:0040014 373 0.027
negative regulation of gene expression epigenetic GO:0045814 2 0.027
positive regulation of multicellular organism growth GO:0040018 352 0.026
cellular component movement GO:0006928 388 0.026
myosin filament organization GO:0031033 138 0.026
regulation of nematode larval development GO:0061062 260 0.026
regulation of meiotic cell cycle GO:0051445 136 0.026
regulation of cell cycle GO:0051726 194 0.026
actin filament based process GO:0030029 191 0.026
meiotic nuclear division GO:0007126 300 0.025
cellular protein metabolic process GO:0044267 279 0.025
muscle cell development GO:0055001 158 0.025
cell migration GO:0016477 306 0.025
growth GO:0040007 562 0.024
protein complex biogenesis GO:0070271 186 0.024
actomyosin structure organization GO:0031032 154 0.024
negative regulation of multicellular organismal process GO:0051241 236 0.024
regulation of developmental growth GO:0048638 389 0.023
negative regulation of vulval development GO:0040027 206 0.023
small molecule metabolic process GO:0044281 186 0.023
macromolecular complex assembly GO:0065003 193 0.023
striated muscle cell differentiation GO:0051146 158 0.023
developmental growth GO:0048589 412 0.022
cell division GO:0051301 262 0.022
negative regulation of post embryonic development GO:0048581 208 0.022
oocyte differentiation GO:0009994 45 0.021
ion transport GO:0006811 113 0.021
myosin filament assembly GO:0031034 138 0.021
striated muscle cell development GO:0055002 157 0.021
muscle tissue development GO:0060537 1 0.021
posttranscriptional gene silencing by rna GO:0035194 143 0.021
oocyte axis specification GO:0007309 2 0.021
posttranscriptional regulation of gene expression GO:0010608 166 0.020
positive regulation of multicellular organismal process GO:0051240 417 0.020
cellular component morphogenesis GO:0032989 318 0.020
defense response to gram negative bacterium GO:0050829 64 0.020
cellular response to abiotic stimulus GO:0071214 4 0.020
gene silencing by rna GO:0031047 143 0.020
negative regulation of developmental process GO:0051093 227 0.020
mitotic nuclear division GO:0007067 89 0.019
sensory organ morphogenesis GO:0090596 2 0.019
oocyte development GO:0048599 44 0.019
regulation of growth GO:0040008 409 0.019
ribosome biogenesis GO:0042254 4 0.019
cell cycle process GO:0022402 482 0.019
positive regulation of growth GO:0045927 369 0.018
rna interference GO:0016246 137 0.018
localization of cell GO:0051674 313 0.018
secretion by cell GO:0032940 138 0.018
oocyte construction GO:0007308 2 0.018
pronuclear migration GO:0035046 51 0.018
organic substance catabolic process GO:1901575 294 0.018
establishment of localization in cell GO:0051649 318 0.017
phosphate containing compound metabolic process GO:0006796 232 0.017
secretion GO:0046903 147 0.017
striated muscle myosin thick filament assembly GO:0071688 138 0.017
post embryonic organ development GO:0048569 336 0.017
catabolic process GO:0009056 318 0.017
positive regulation of cellular metabolic process GO:0031325 178 0.016
regulation of post embryonic development GO:0048580 260 0.016
ribonucleoprotein complex assembly GO:0022618 4 0.016
skeletal muscle organ development GO:0060538 3 0.016
protein localization GO:0008104 205 0.015
protein modification process GO:0036211 207 0.015
regulation of multicellular organismal development GO:2000026 317 0.014
regulation of localization GO:0032879 194 0.014
macromolecule catabolic process GO:0009057 202 0.014
positive regulation of developmental process GO:0051094 408 0.014
transmembrane transport GO:0055085 110 0.013
regulation of cell division GO:0051302 142 0.013
chromosome segregation GO:0007059 180 0.013
phosphorus metabolic process GO:0006793 232 0.013
regulation of organelle organization GO:0033043 164 0.013
posttranscriptional gene silencing GO:0016441 143 0.013
synaptic growth at neuromuscular junction GO:0051124 1 0.012
embryonic morphogenesis GO:0048598 152 0.012
cation transport GO:0006812 78 0.012
signaling GO:0023052 401 0.012
purine nucleoside metabolic process GO:0042278 92 0.012
regulation of cellular component organization GO:0051128 248 0.012
regulation of organ morphogenesis GO:2000027 4 0.012
defense response to other organism GO:0098542 100 0.012
regulation of epithelial cell proliferation GO:0050678 1 0.012
cell type specific apoptotic process GO:0097285 4 0.012
response to wounding GO:0009611 4 0.012
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.012
neuromuscular junction development GO:0007528 2 0.011
carbohydrate derivative metabolic process GO:1901135 141 0.011
organonitrogen compound metabolic process GO:1901564 151 0.011
ion transmembrane transport GO:0034220 91 0.011
regulation of apoptotic signaling pathway GO:2001233 1 0.011
protein oligomerization GO:0051259 4 0.011
regulation of cytoplasmic transport GO:1903649 3 0.011
organic acid metabolic process GO:0006082 47 0.011
rrna metabolic process GO:0016072 3 0.011
response to abiotic stimulus GO:0009628 152 0.011
regulation of nuclear division GO:0051783 115 0.011
organic substance transport GO:0071702 113 0.011
positive regulation of protein transport GO:0051222 4 0.011
system process GO:0003008 136 0.010
regulation of meiosis GO:0040020 94 0.010
rrna processing GO:0006364 3 0.010
mitotic cell cycle process GO:1903047 194 0.010
protein catabolic process GO:0030163 162 0.010

his-4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.018
immune system disease DOID:2914 0 0.011
bone marrow disease DOID:4961 0 0.011
hematopoietic system disease DOID:74 0 0.011
nervous system disease DOID:863 0 0.011