Caenorhabditis elegans

68 known processes

unc-44 (CELE_B0350.2)

Protein UNC-44

unc-44 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular component movement GO:0006928 388 0.428
developmental process involved in reproduction GO:0003006 1165 0.325
regulation of developmental process GO:0050793 684 0.285
sex differentiation GO:0007548 909 0.280
axon development GO:0061564 163 0.278
cellular component morphogenesis GO:0032989 318 0.275
locomotion GO:0040011 1634 0.253
signaling GO:0023052 401 0.245
regulation of locomotion GO:0040012 161 0.239
multicellular organism reproduction GO:0032504 819 0.206
body morphogenesis GO:0010171 620 0.197
embryo development ending in birth or egg hatching GO:0009792 2992 0.195
Worm
regulation of multicellular organismal process GO:0051239 726 0.188
regulation of vulval development GO:0040028 248 0.166
behavior GO:0007610 527 0.142
organelle assembly GO:0070925 214 0.136
cell morphogenesis GO:0000902 163 0.128
gonad development GO:0008406 840 0.124
macromolecule localization GO:0033036 771 0.122
Fly
neurogenesis GO:0022008 236 0.121
regulation of localization GO:0032879 194 0.120
single organism localization GO:1902578 518 0.111
Fly
cell part morphogenesis GO:0032990 152 0.109
organ development GO:0048513 1102 0.106
establishment of localization in cell GO:0051649 318 0.103
development of primary sexual characteristics GO:0045137 840 0.102
cellular component biogenesis GO:0044085 297 0.098
regulation of developmental growth GO:0048638 389 0.097
reproductive structure development GO:0048608 850 0.092
response to chemical GO:0042221 356 0.091
positive regulation of cell communication GO:0010647 69 0.091
anatomical structure formation involved in morphogenesis GO:0048646 250 0.091
generation of neurons GO:0048699 235 0.090
multi multicellular organism process GO:0044706 390 0.088
positive regulation of multicellular organism growth GO:0040018 352 0.087
regulation of biological quality GO:0065008 741 0.086
Fly
localization of cell GO:0051674 313 0.085
cell motility GO:0048870 313 0.084
neuron development GO:0048666 199 0.082
reproductive behavior GO:0019098 387 0.082
regulation of cell morphogenesis GO:0022604 40 0.081
hermaphrodite genitalia development GO:0040035 734 0.080
positive regulation of gene expression GO:0010628 112 0.080
cellular localization GO:0051641 360 0.079
Fly
positive regulation of growth GO:0045927 369 0.078
genitalia development GO:0048806 741 0.076
cell development GO:0048468 696 0.073
actomyosin structure organization GO:0031032 154 0.073
aging GO:0007568 812 0.072
organelle organization GO:0006996 783 0.072
developmental growth GO:0048589 412 0.070
positive regulation of signaling GO:0023056 66 0.070
regulation of post embryonic development GO:0048580 260 0.070
regulation of growth GO:0040008 409 0.070
protein catabolic process GO:0030163 162 0.069
oviposition GO:0018991 364 0.069
multicellular organismal aging GO:0010259 812 0.069
multicellular organismal reproductive process GO:0048609 815 0.067
multi organism behavior GO:0051705 389 0.066
cellular component assembly involved in morphogenesis GO:0010927 183 0.066
regulation of neuron projection development GO:0010975 31 0.064
neuron projection development GO:0031175 187 0.064
myosin filament assembly GO:0031034 138 0.062
myofibril assembly GO:0030239 154 0.062
cellular macromolecular complex assembly GO:0034622 184 0.061
neuron differentiation GO:0030182 217 0.061
actin cytoskeleton organization GO:0030036 184 0.060
embryo development GO:0009790 3052 0.060
Worm
neuron projection morphogenesis GO:0048812 114 0.060
striated muscle myosin thick filament assembly GO:0071688 138 0.059
regulation of nematode larval development GO:0061062 260 0.058
cellular component assembly GO:0022607 293 0.057
protein complex biogenesis GO:0070271 186 0.057
multicellular organismal reproductive behavior GO:0033057 384 0.055
regulation of cell differentiation GO:0045595 81 0.054
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.053
lipid storage GO:0019915 565 0.053
cytoskeleton organization GO:0007010 339 0.052
Fly
protein complex assembly GO:0006461 186 0.052
negative regulation of biological process GO:0048519 567 0.052
multicellular organism growth GO:0035264 385 0.052
muscle cell development GO:0055001 158 0.051
regulation of cellular component organization GO:0051128 248 0.051
nucleoside triphosphate catabolic process GO:0009143 72 0.050
macromolecule catabolic process GO:0009057 202 0.049
death GO:0016265 547 0.049
positive regulation of developmental process GO:0051094 408 0.049
maintenance of location GO:0051235 580 0.048
Fly
positive regulation of developmental growth GO:0048639 354 0.048
nervous system development GO:0007399 253 0.047
multi organism reproductive behavior GO:0044705 387 0.046
macromolecular complex subunit organization GO:0043933 320 0.046
determination of adult lifespan GO:0008340 812 0.046
single organism transport GO:0044765 447 0.046
lipid localization GO:0010876 573 0.046
muscle structure development GO:0061061 191 0.045
macromolecule biosynthetic process GO:0009059 250 0.044
vesicle mediated transport GO:0016192 852 0.043
multi organism reproductive process GO:0044703 867 0.043
response to external stimulus GO:0009605 289 0.043
cell projection organization GO:0030030 231 0.043
regulation of response to stimulus GO:0048583 243 0.042
single organism organelle organization GO:1902589 501 0.042
Fly
intracellular transport GO:0046907 77 0.041
response to topologically incorrect protein GO:0035966 82 0.041
cell migration GO:0016477 306 0.041
ribonucleotide catabolic process GO:0009261 75 0.041
cell projection morphogenesis GO:0048858 148 0.040
single organism reproductive process GO:0044702 1196 0.040
actin filament based process GO:0030029 191 0.040
gamete generation GO:0007276 461 0.039
post embryonic organ development GO:0048569 336 0.038
regulation of multicellular organism growth GO:0040014 373 0.038
negative regulation of developmental process GO:0051093 227 0.038
secretion by cell GO:0032940 138 0.038
protein metabolic process GO:0019538 422 0.037
single organism intracellular transport GO:1902582 70 0.036
positive regulation of rna biosynthetic process GO:1902680 102 0.035
reproductive system development GO:0061458 850 0.035
apoptotic process GO:0006915 478 0.035
positive regulation of cellular process GO:0048522 332 0.034
developmental maturation GO:0021700 26 0.034
macromolecular complex assembly GO:0065003 193 0.033
cellular macromolecule localization GO:0070727 75 0.032
Fly
negative regulation of post embryonic development GO:0048581 208 0.032
male sex differentiation GO:0046661 86 0.032
regulation of signal transduction GO:0009966 135 0.031
growth GO:0040007 562 0.030
regulation of cell projection organization GO:0031344 38 0.030
single organism signaling GO:0044700 401 0.030
regulation of transport GO:0051049 91 0.029
purine nucleotide metabolic process GO:0006163 95 0.029
neuromuscular process GO:0050905 1 0.029
cellular protein complex assembly GO:0043623 178 0.029
chemotaxis GO:0006935 120 0.028
muscle organ morphogenesis GO:0048644 4 0.028
regulation of apoptotic signaling pathway GO:2001233 1 0.028
cilium assembly GO:0042384 28 0.028
negative regulation of nematode larval development GO:0061064 208 0.027
establishment of localization GO:0051234 1171 0.027
catabolic process GO:0009056 318 0.027
striated muscle cell differentiation GO:0051146 158 0.027
cell cell signaling GO:0007267 118 0.026
muscle cell differentiation GO:0042692 171 0.026
gene expression GO:0010467 412 0.026
protein localization GO:0008104 205 0.026
Fly
regulation of nervous system development GO:0051960 41 0.026
ribonucleoside triphosphate metabolic process GO:0009199 87 0.026
cell substrate adhesion GO:0031589 1 0.026
organonitrogen compound metabolic process GO:1901564 151 0.025
transport GO:0006810 1093 0.025
negative regulation of multicellular organismal process GO:0051241 236 0.025
myosin filament organization GO:0031033 138 0.024
organic substance biosynthetic process GO:1901576 323 0.023
secretion GO:0046903 147 0.023
digestive system development GO:0055123 122 0.023
organic substance transport GO:0071702 113 0.023
cuticle development GO:0042335 100 0.023
cell fate commitment GO:0045165 139 0.022
purine nucleoside triphosphate metabolic process GO:0009144 87 0.022
germ cell development GO:0007281 351 0.022
positive regulation of rna metabolic process GO:0051254 103 0.022
microtubule based transport GO:0010970 19 0.022
cellular protein localization GO:0034613 75 0.022
Fly
ribonucleoside catabolic process GO:0042454 77 0.021
nucleobase containing compound metabolic process GO:0006139 406 0.021
sexual reproduction GO:0019953 546 0.021
regulation of signaling GO:0023051 172 0.021
purine ribonucleotide catabolic process GO:0009154 75 0.021
cell death GO:0008219 547 0.021
post embryonic development GO:0009791 2152 0.021
axon guidance GO:0007411 82 0.021
establishment of protein localization to membrane GO:0090150 3 0.020
inductive cell migration GO:0040039 145 0.020
regulation of multicellular organismal development GO:2000026 317 0.020
striated muscle cell development GO:0055002 157 0.020
regulation of cell development GO:0060284 49 0.020
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.020
peptidyl lysine trimethylation GO:0018023 2 0.020
programmed cell death GO:0012501 500 0.019
biosynthetic process GO:0009058 323 0.019
negative regulation of cellular process GO:0048523 239 0.019
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.019
response to acid chemical GO:0001101 4 0.018
cellular protein metabolic process GO:0044267 279 0.018
signal transduction GO:0007165 317 0.018
purine containing compound catabolic process GO:0072523 75 0.018
nucleoside phosphate catabolic process GO:1901292 77 0.018
negative regulation of vulval development GO:0040027 206 0.018
protein complex subunit organization GO:0071822 280 0.018
single organism behavior GO:0044708 83 0.018
positive regulation of hydrolase activity GO:0051345 38 0.017
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.017
rna biosynthetic process GO:0032774 169 0.017
regulation of organelle organization GO:0033043 164 0.017
macromolecule modification GO:0043412 218 0.017
aromatic compound biosynthetic process GO:0019438 192 0.017
nucleobase containing compound biosynthetic process GO:0034654 184 0.017
membrane invagination GO:0010324 98 0.016
cell maturation GO:0048469 26 0.016
protein transport GO:0015031 45 0.016
phagocytosis GO:0006909 115 0.016
organophosphate metabolic process GO:0019637 125 0.016
establishment of protein localization GO:0045184 50 0.016
membrane organization GO:0061024 135 0.016
positive regulation of nucleic acid templated transcription GO:1903508 102 0.016
regulation of cellular component size GO:0032535 40 0.016
positive regulation of biosynthetic process GO:0009891 109 0.016
collagen and cuticulin based cuticle development GO:0040002 99 0.016
synaptic transmission GO:0007268 106 0.016
organic substance catabolic process GO:1901575 294 0.015
cellular response to unfolded protein GO:0034620 71 0.015
cell recognition GO:0008037 85 0.015
neuron projection guidance GO:0097485 82 0.015
meiotic nuclear division GO:0007126 300 0.015
posttranscriptional regulation of gene expression GO:0010608 166 0.015
regulation of cellular component movement GO:0051270 62 0.015
regulation of cell motility GO:2000145 57 0.015
phagocytosis engulfment GO:0006911 98 0.014
regulation of cell communication GO:0010646 176 0.014
receptor mediated endocytosis GO:0006898 715 0.014
neuron recognition GO:0008038 83 0.014
rna metabolic process GO:0016070 228 0.014
chromosome segregation GO:0007059 180 0.014
vulval development GO:0040025 333 0.014
positive regulation of transcription dna templated GO:0045893 102 0.013
adult locomotory behavior GO:0008344 1 0.013
purine nucleoside catabolic process GO:0006152 75 0.013
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.013
amine metabolic process GO:0009308 15 0.013
protein oligomerization GO:0051259 4 0.013
purine ribonucleoside catabolic process GO:0046130 75 0.013
chromosome organization GO:0051276 104 0.013
regulation of cellular ketone metabolic process GO:0010565 3 0.013
regulation of metabolic process GO:0019222 478 0.013
positive regulation of macromolecule metabolic process GO:0010604 149 0.013
atp catabolic process GO:0006200 27 0.012
metal ion transport GO:0030001 49 0.012
cellular biosynthetic process GO:0044249 315 0.012
carboxylic acid metabolic process GO:0019752 34 0.012
learning or memory GO:0007611 27 0.012
protein modification process GO:0036211 207 0.012
cell type specific apoptotic process GO:0097285 4 0.012
cell growth GO:0016049 44 0.012
cellular amine metabolic process GO:0044106 15 0.012
response to oxygen levels GO:0070482 22 0.012
cytoskeleton dependent intracellular transport GO:0030705 19 0.012
regulation of anatomical structure morphogenesis GO:0022603 51 0.012
locomotory behavior GO:0007626 40 0.012
ribonucleoside triphosphate catabolic process GO:0009203 72 0.011
sensory organ morphogenesis GO:0090596 2 0.011
regulation of protein metabolic process GO:0051246 81 0.011
endocytosis GO:0006897 819 0.011
regulation of gene expression GO:0010468 366 0.011
digestive tract development GO:0048565 122 0.011
response to wounding GO:0009611 4 0.011
transcription from rna polymerase ii promoter GO:0006366 149 0.011
nucleoside catabolic process GO:0009164 78 0.011
microtubule based process GO:0007017 182 0.011
ras protein signal transduction GO:0007265 31 0.011
nucleoside metabolic process GO:0009116 99 0.011
regulation of hydrolase activity GO:0051336 45 0.011
purine nucleotide catabolic process GO:0006195 75 0.011
cellular amino acid metabolic process GO:0006520 15 0.011
axonogenesis GO:0007409 102 0.010
regulation of mitotic cell cycle GO:0007346 76 0.010
negative regulation of ion transmembrane transport GO:0034766 3 0.010
organelle fission GO:0048285 363 0.010
regulation of synaptic plasticity GO:0048167 1 0.010
nucleoside triphosphate metabolic process GO:0009141 87 0.010

unc-44 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.183
cardiovascular system disease DOID:1287 0 0.183
heart disease DOID:114 0 0.024
musculoskeletal system disease DOID:17 0 0.019
nervous system disease DOID:863 0 0.018
myopathy DOID:423 0 0.016
muscular disease DOID:0080000 0 0.016
muscle tissue disease DOID:66 0 0.016
cardiomyopathy DOID:0050700 0 0.015
dilated cardiomyopathy DOID:12930 0 0.015
intrinsic cardiomyopathy DOID:0060036 0 0.015
disease of metabolism DOID:0014667 0 0.012
carbohydrate metabolic disorder DOID:2978 0 0.012
inherited metabolic disorder DOID:655 0 0.012