Caenorhabditis elegans

85 known processes

ref-2 (CELE_C47C12.3)

Protein REF-2

ref-2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
neuron projection guidance GO:0097485 82 0.672
Mouse
locomotion GO:0040011 1634 0.451
post embryonic development GO:0009791 2152 0.407
taxis GO:0042330 128 0.394
Mouse
chemotaxis GO:0006935 120 0.369
Mouse
rna biosynthetic process GO:0032774 169 0.349
organ development GO:0048513 1102 0.338
positive regulation of nucleic acid templated transcription GO:1903508 102 0.304
Mouse Fly
cell development GO:0048468 696 0.302
Zebrafish Mouse
developmental process involved in reproduction GO:0003006 1165 0.286
axonogenesis GO:0007409 102 0.282
Mouse
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.279
Mouse Fly
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.274
Mouse Fly
positive regulation of rna biosynthetic process GO:1902680 102 0.270
Mouse Fly
cell migration GO:0016477 306 0.269
Fly
embryo development GO:0009790 3052 0.258
Zebrafish Mouse
cellular component morphogenesis GO:0032989 318 0.258
Mouse
nucleobase containing compound biosynthetic process GO:0034654 184 0.255
axon guidance GO:0007411 82 0.254
Mouse
gonad development GO:0008406 840 0.247
cellular component movement GO:0006928 388 0.244
Mouse Fly
embryo development ending in birth or egg hatching GO:0009792 2992 0.241
Zebrafish Mouse
regulation of developmental process GO:0050793 684 0.231
gene expression GO:0010467 412 0.220
head development GO:0060322 1 0.211
Human Zebrafish Mouse
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.207
Zebrafish Mouse Fly
establishment of localization GO:0051234 1171 0.202
Mouse
cellular macromolecule biosynthetic process GO:0034645 247 0.201
regulation of transcription dna templated GO:0006355 164 0.200
Zebrafish Mouse Fly
nucleic acid metabolic process GO:0090304 299 0.200
reproductive structure development GO:0048608 850 0.199
response to chemical GO:0042221 356 0.195
Mouse
neuron projection morphogenesis GO:0048812 114 0.194
Mouse
positive regulation of metabolic process GO:0009893 187 0.191
Mouse Fly
transport GO:0006810 1093 0.191
Mouse
aromatic compound biosynthetic process GO:0019438 192 0.185
positive regulation of cellular biosynthetic process GO:0031328 109 0.183
Mouse Fly
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.183
Mouse Fly
single organism reproductive process GO:0044702 1196 0.182
positive regulation of transcription dna templated GO:0045893 102 0.182
Mouse Fly
positive regulation of rna metabolic process GO:0051254 103 0.181
Mouse Fly
generation of neurons GO:0048699 235 0.177
cell part morphogenesis GO:0032990 152 0.176
Mouse
heterocycle biosynthetic process GO:0018130 187 0.174
negative regulation of biological process GO:0048519 567 0.171
Zebrafish Mouse
regulation of gene expression GO:0010468 366 0.170
Zebrafish Mouse Fly
receptor mediated endocytosis GO:0006898 715 0.164
development of primary sexual characteristics GO:0045137 840 0.163
organic cyclic compound biosynthetic process GO:1901362 195 0.162
anatomical structure formation involved in morphogenesis GO:0048646 250 0.161
Zebrafish Mouse
neuron projection development GO:0031175 187 0.161
Mouse
regulation of primary metabolic process GO:0080090 292 0.161
Zebrafish Mouse Fly
reproductive system development GO:0061458 850 0.161
cell fate commitment GO:0045165 139 0.160
biosynthetic process GO:0009058 323 0.157
regulation of cellular biosynthetic process GO:0031326 189 0.157
Zebrafish Mouse Fly
nucleic acid templated transcription GO:0097659 169 0.155
regulation of rna biosynthetic process GO:2001141 165 0.155
Zebrafish Mouse Fly
transcription dna templated GO:0006351 168 0.154
regulation of nitrogen compound metabolic process GO:0051171 222 0.154
Zebrafish Mouse Fly
cellular nitrogen compound biosynthetic process GO:0044271 192 0.154
cell motility GO:0048870 313 0.153
Fly
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.153
Zebrafish Mouse Fly
regulation of macromolecule metabolic process GO:0060255 421 0.153
Zebrafish Mouse Fly
regulation of multicellular organismal process GO:0051239 726 0.151
sensory organ morphogenesis GO:0090596 2 0.150
Zebrafish
multi organism reproductive process GO:0044703 867 0.147
embryonic morphogenesis GO:0048598 152 0.145
Zebrafish Mouse
cell projection morphogenesis GO:0048858 148 0.144
Mouse
positive regulation of macromolecule metabolic process GO:0010604 149 0.143
Mouse Fly
body morphogenesis GO:0010171 620 0.140
multi organism reproductive behavior GO:0044705 387 0.138
multicellular organismal aging GO:0010259 812 0.137
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.137
Mouse
organelle organization GO:0006996 783 0.136
axon development GO:0061564 163 0.136
Mouse
nucleobase containing compound metabolic process GO:0006139 406 0.136
signaling GO:0023052 401 0.134
Zebrafish Mouse Fly
nervous system development GO:0007399 253 0.133
neurogenesis GO:0022008 236 0.131
regulation of rna metabolic process GO:0051252 173 0.130
Zebrafish Mouse Fly
positive regulation of cellular process GO:0048522 332 0.130
Mouse Fly
multicellular organism reproduction GO:0032504 819 0.129
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.129
Mouse Fly
growth GO:0040007 562 0.126
endocytosis GO:0006897 819 0.126
multicellular organismal reproductive process GO:0048609 815 0.116
single organism localization GO:1902578 518 0.116
Mouse
response to external stimulus GO:0009605 289 0.114
Mouse
cell morphogenesis involved in differentiation GO:0000904 112 0.113
Mouse
positive regulation of multicellular organismal process GO:0051240 417 0.112
oviposition GO:0018991 364 0.112
aging GO:0007568 812 0.112
cell projection organization GO:0030030 231 0.111
Mouse
transcription from rna polymerase ii promoter GO:0006366 149 0.111
Mouse Fly
sex differentiation GO:0007548 909 0.110
cell cycle GO:0007049 526 0.109
rna metabolic process GO:0016070 228 0.108
macromolecule localization GO:0033036 771 0.107
meiotic nuclear division GO:0007126 300 0.105
regulation of metabolic process GO:0019222 478 0.104
Zebrafish Mouse Fly
negative regulation of metabolic process GO:0009892 240 0.103
Zebrafish Mouse
developmental growth GO:0048589 412 0.103
multi organism behavior GO:0051705 389 0.102
regulation of macromolecule biosynthetic process GO:0010556 189 0.102
Zebrafish Mouse Fly
regulation of biosynthetic process GO:0009889 189 0.102
Zebrafish Mouse Fly
neuron development GO:0048666 199 0.102
Mouse
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.101
Mouse Fly
regulation of nucleic acid templated transcription GO:1903506 165 0.101
Zebrafish Mouse Fly
organic substance biosynthetic process GO:1901576 323 0.101
single organism signaling GO:0044700 401 0.101
Zebrafish Mouse Fly
cellular biosynthetic process GO:0044249 315 0.101
regulation of cellular metabolic process GO:0031323 305 0.099
Zebrafish Mouse Fly
regulation of biological quality GO:0065008 741 0.099
single organism organelle organization GO:1902589 501 0.098
programmed cell death GO:0012501 500 0.098
vesicle mediated transport GO:0016192 852 0.098
signal transduction GO:0007165 317 0.097
Zebrafish Mouse Fly
determination of adult lifespan GO:0008340 812 0.097
digestive tract morphogenesis GO:0048546 76 0.097
vulval development GO:0040025 333 0.096
cell morphogenesis GO:0000902 163 0.096
Mouse
behavior GO:0007610 527 0.096
regionalization GO:0003002 31 0.093
Zebrafish Mouse
macromolecule biosynthetic process GO:0009059 250 0.091
apoptotic process GO:0006915 478 0.090
negative regulation of multicellular organismal process GO:0051241 236 0.090
neuron differentiation GO:0030182 217 0.089
epithelium development GO:0060429 68 0.088
Zebrafish Mouse
inductive cell migration GO:0040039 145 0.087
mesoderm development GO:0007498 27 0.085
tube morphogenesis GO:0035239 79 0.084
Zebrafish Mouse
cell death GO:0008219 547 0.084
negative regulation of macromolecule metabolic process GO:0010605 229 0.084
Zebrafish Mouse
positive regulation of developmental process GO:0051094 408 0.083
negative regulation of gene expression GO:0010629 217 0.082
Zebrafish Mouse
regulation of vulval development GO:0040028 248 0.081
positive regulation of cellular metabolic process GO:0031325 178 0.080
Mouse Fly
sexual reproduction GO:0019953 546 0.077
Fly
cell cycle process GO:0022402 482 0.077
positive regulation of biosynthetic process GO:0009891 109 0.077
Mouse Fly
neuroblast fate determination GO:0007400 1 0.075
negative regulation of cellular process GO:0048523 239 0.074
Zebrafish Mouse
gamete generation GO:0007276 461 0.074
Fly
maintenance of location GO:0051235 580 0.073
single organism transport GO:0044765 447 0.072
Mouse
lipid localization GO:0010876 573 0.071
regulation of post embryonic development GO:0048580 260 0.071
multi multicellular organism process GO:0044706 390 0.071
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.069
Zebrafish Mouse
reproductive behavior GO:0019098 387 0.069
cell division GO:0051301 262 0.067
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.067
Fly
pattern specification process GO:0007389 59 0.066
Zebrafish Mouse
gastrulation GO:0007369 58 0.066
embryonic body morphogenesis GO:0010172 49 0.066
lipid storage GO:0019915 565 0.066
regulation of developmental growth GO:0048638 389 0.065
cell fate commitment involved in formation of primary germ layer GO:0060795 33 0.065
regulation of nematode larval development GO:0061062 260 0.065
regulation of locomotion GO:0040012 161 0.064
membrane organization GO:0061024 135 0.063
negative regulation of cellular biosynthetic process GO:0031327 65 0.063
Zebrafish Mouse
response to wounding GO:0009611 4 0.063
regulation of multicellular organism growth GO:0040014 373 0.063
post embryonic organ development GO:0048569 336 0.062
Fly
hermaphrodite genitalia development GO:0040035 734 0.061
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.061
Zebrafish Mouse
regulation of cell division GO:0051302 142 0.061
cell surface receptor signaling pathway GO:0007166 149 0.060
Zebrafish Mouse Fly
multicellular organismal reproductive behavior GO:0033057 384 0.060
establishment of localization in cell GO:0051649 318 0.059
Mouse
muscle tissue development GO:0060537 1 0.059
regulation of multicellular organismal development GO:2000026 317 0.058
positive regulation of multicellular organism growth GO:0040018 352 0.058
positive regulation of growth GO:0045927 369 0.058
negative regulation of transcription from rna polymerase ii promoter GO:0000122 45 0.057
positive regulation of developmental growth GO:0048639 354 0.057
female gamete generation GO:0007292 254 0.056
tube development GO:0035295 126 0.055
Zebrafish Mouse Fly
regulation of meiosis GO:0040020 94 0.055
regulation of response to stimulus GO:0048583 243 0.055
Zebrafish Mouse
regulation of neuron differentiation GO:0045664 40 0.054
mesodermal cell fate specification GO:0007501 13 0.054
defense response GO:0006952 296 0.054
mesodermal cell differentiation GO:0048333 15 0.053
regulation of cellular component organization GO:0051128 248 0.053
response to other organism GO:0051707 101 0.052
muscle structure development GO:0061061 191 0.051
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.051
Zebrafish Mouse
mitotic cell cycle process GO:1903047 194 0.051
single organism behavior GO:0044708 83 0.050
Mouse
cellular localization GO:0051641 360 0.049
Mouse
response to biotic stimulus GO:0009607 101 0.049
genitalia development GO:0048806 741 0.049
positive regulation of gene expression GO:0010628 112 0.049
Mouse Fly
negative regulation of developmental process GO:0051093 227 0.048
negative regulation of transcription dna templated GO:0045892 53 0.048
Zebrafish Mouse
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.048
Zebrafish Mouse
negative regulation of vulval development GO:0040027 206 0.048
tissue development GO:0009888 112 0.048
Zebrafish Mouse
germ cell development GO:0007281 351 0.047
cellular response to chemical stimulus GO:0070887 129 0.047
cellular response to organic substance GO:0071310 119 0.047
response to organic substance GO:0010033 131 0.047
protein localization GO:0008104 205 0.047
Mouse
organelle fission GO:0048285 363 0.046
dauer larval development GO:0040024 92 0.045
localization of cell GO:0051674 313 0.045
Fly
regulation of localization GO:0032879 194 0.045
Mouse
muscle cell differentiation GO:0042692 171 0.044
regulation of growth GO:0040008 409 0.044
macromolecule modification GO:0043412 218 0.043
negative regulation of rna biosynthetic process GO:1902679 53 0.042
Zebrafish Mouse
epidermis development GO:0008544 24 0.042
negative regulation of nematode larval development GO:0061064 208 0.041
anterior posterior pattern specification GO:0009952 27 0.041
Zebrafish Mouse
protein modification process GO:0036211 207 0.041
cellular component biogenesis GO:0044085 297 0.040
response to external biotic stimulus GO:0043207 101 0.040
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.040
oogenesis GO:0048477 229 0.039
response to abiotic stimulus GO:0009628 152 0.039
striated muscle cell differentiation GO:0051146 158 0.039
regulation of organ morphogenesis GO:2000027 4 0.039
regulation of cell differentiation GO:0045595 81 0.039
regulation of reproductive process GO:2000241 66 0.039
positive regulation of neurogenesis GO:0050769 4 0.038
molting cycle GO:0042303 281 0.038
cellular protein metabolic process GO:0044267 279 0.038
protein complex subunit organization GO:0071822 280 0.037
mesoderm morphogenesis GO:0048332 24 0.037
epithelial cell proliferation GO:0050673 1 0.037
negative regulation of post embryonic development GO:0048581 208 0.036
digestive system development GO:0055123 122 0.036
Fly
death GO:0016265 547 0.036
organelle assembly GO:0070925 214 0.036
protein complex assembly GO:0006461 186 0.035
protein metabolic process GO:0019538 422 0.035
immune response GO:0006955 192 0.035
defense response to fungus GO:0050832 19 0.035
phosphate containing compound metabolic process GO:0006796 232 0.034
regulation of cell cycle process GO:0010564 145 0.034
cell type specific apoptotic process GO:0097285 4 0.034
macromolecular complex subunit organization GO:0043933 320 0.034
digestive tract development GO:0048565 122 0.033
Fly
canonical wnt signaling pathway GO:0060070 3 0.033
Zebrafish
cytoskeleton organization GO:0007010 339 0.032
negative regulation of nucleic acid templated transcription GO:1903507 53 0.032
Zebrafish Mouse
striated muscle cell development GO:0055002 157 0.032
multicellular organism growth GO:0035264 385 0.032
regulation of neurogenesis GO:0050767 40 0.031
actin cytoskeleton organization GO:0030036 184 0.030
positive regulation of neuron differentiation GO:0045666 4 0.030
muscle cell development GO:0055001 158 0.030
regulation of meiotic cell cycle GO:0051445 136 0.030
dendrite development GO:0016358 42 0.030
regulation of signaling GO:0023051 172 0.030
Zebrafish Mouse
cellular protein modification process GO:0006464 207 0.030
negative regulation of biosynthetic process GO:0009890 65 0.030
Zebrafish Mouse
bmp signaling pathway GO:0030509 3 0.029
regulation of cell cycle GO:0051726 194 0.029
cell proliferation GO:0008283 116 0.029
Zebrafish
myofibril assembly GO:0030239 154 0.029
actin filament based process GO:0030029 191 0.029
epidermal cell fate specification GO:0009957 5 0.028
proximal distal pattern formation GO:0009954 6 0.028
protein phosphorylation GO:0006468 85 0.028
regulation of epithelial cell proliferation GO:0050678 1 0.028
cellular component assembly involved in morphogenesis GO:0010927 183 0.028
organic substance transport GO:0071702 113 0.028
Mouse
regulation of nervous system development GO:0051960 41 0.028
regulation of organelle organization GO:0033043 164 0.028
actomyosin structure organization GO:0031032 154 0.027
regulation of bmp signaling pathway GO:0030510 3 0.027
phosphorus metabolic process GO:0006793 232 0.027
regulation of cell migration GO:0030334 55 0.026
system process GO:0003008 136 0.026
Mouse
cellular component assembly GO:0022607 293 0.026
epithelial tube morphogenesis GO:0060562 1 0.025
Zebrafish Mouse
regeneration GO:0031099 4 0.025
skeletal muscle organ development GO:0060538 3 0.025
organ morphogenesis GO:0009887 67 0.025
Zebrafish Mouse Fly
phagocytosis GO:0006909 115 0.025
neuron recognition GO:0008038 83 0.025
cellular macromolecular complex assembly GO:0034622 184 0.024
oxoacid metabolic process GO:0043436 47 0.024
regulation of cell communication GO:0010646 176 0.024
Zebrafish Mouse
defense response to other organism GO:0098542 100 0.024
nematode male tail tip morphogenesis GO:0045138 77 0.024
macromolecular complex assembly GO:0065003 193 0.023
negative regulation of neurogenesis GO:0050768 4 0.023
cellular response to stress GO:0033554 162 0.023
small molecule metabolic process GO:0044281 186 0.022
asymmetric cell division GO:0008356 36 0.022
regulation of cell fate commitment GO:0010453 22 0.022
male sex differentiation GO:0046661 86 0.022
myosin filament assembly GO:0031034 138 0.022
regulation of cell proliferation GO:0042127 105 0.022
Zebrafish
regulation of transport GO:0051049 91 0.021
Mouse
organelle localization GO:0051640 127 0.021
intracellular receptor signaling pathway GO:0030522 2 0.021
spindle organization GO:0007051 92 0.021
regulation of cell motility GO:2000145 57 0.021
cellular protein complex assembly GO:0043623 178 0.021
regulation of cell fate specification GO:0042659 22 0.021
single organism cellular localization GO:1902580 72 0.021
Mouse
male anatomical structure morphogenesis GO:0090598 78 0.021
negative regulation of cellular metabolic process GO:0031324 95 0.020
Zebrafish Mouse
secretion GO:0046903 147 0.020
collagen and cuticulin based cuticle development GO:0040002 99 0.020
skin development GO:0043588 24 0.020
protein complex biogenesis GO:0070271 186 0.020
chemosensory behavior GO:0007635 33 0.019
regulation of signal transduction GO:0009966 135 0.019
Zebrafish Mouse
regulation of cellular ketone metabolic process GO:0010565 3 0.019
ovulation GO:0030728 33 0.019
carboxylic acid metabolic process GO:0019752 34 0.019
cellular response to abiotic stimulus GO:0071214 4 0.019
regulation of cellular component movement GO:0051270 62 0.019
regulation of nuclear division GO:0051783 115 0.019
neurological system process GO:0050877 53 0.019
Mouse
embryonic pattern specification GO:0009880 21 0.018
stem cell fate commitment GO:0048865 5 0.018
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.018
Mouse
meiotic cell cycle GO:0051321 335 0.018
adult behavior GO:0030534 3 0.018
Mouse
organic acid metabolic process GO:0006082 47 0.018
cellular amine metabolic process GO:0044106 15 0.018
striated muscle myosin thick filament assembly GO:0071688 138 0.018
apoptotic cell clearance GO:0043277 111 0.018
secretion by cell GO:0032940 138 0.018
mitotic nuclear division GO:0007067 89 0.018
negative regulation of rna metabolic process GO:0051253 53 0.018
Zebrafish Mouse
intracellular transport GO:0046907 77 0.018
Mouse
phosphorylation GO:0016310 116 0.018
axon extension GO:0048675 37 0.017
positive regulation of intracellular transport GO:0032388 2 0.017
Mouse
regulation of cytoplasmic transport GO:1903649 3 0.017
Mouse
neuromuscular junction development GO:0007528 2 0.017
regulation of multi organism process GO:0043900 69 0.017
regulation of cellular amino acid metabolic process GO:0006521 0 0.017
cuticle development GO:0042335 100 0.017
intracellular signal transduction GO:0035556 96 0.016
posttranscriptional regulation of gene expression GO:0010608 166 0.016
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 2 0.016
motor neuron axon guidance GO:0008045 13 0.016
axonal fasciculation GO:0007413 79 0.016
microtubule based process GO:0007017 182 0.016
regulation of cellular amine metabolic process GO:0033238 0 0.016
response to fungus GO:0009620 20 0.016
regulation of epithelial cell differentiation GO:0030856 4 0.016
muscle organ morphogenesis GO:0048644 4 0.016
gene silencing by rna GO:0031047 143 0.016
cellular response to oxygen containing compound GO:1901701 21 0.015
regulation of molecular function GO:0065009 89 0.015
Mouse
pharynx development GO:0060465 51 0.015
cellular ketone metabolic process GO:0042180 14 0.015
cellular amino acid metabolic process GO:0006520 15 0.015
amine metabolic process GO:0009308 15 0.015
hormone transport GO:0009914 2 0.015
neuroblast fate commitment GO:0014017 5 0.015
regulation of apoptotic signaling pathway GO:2001233 1 0.015
homeostatic process GO:0042592 51 0.015
peptidyl tyrosine phosphorylation GO:0018108 2 0.015
endodermal cell differentiation GO:0035987 18 0.014
neuron fate specification GO:0048665 8 0.014
cell recognition GO:0008037 85 0.014
posttranscriptional gene silencing by rna GO:0035194 143 0.014
single organism biosynthetic process GO:0044711 91 0.014
positive regulation of cell morphogenesis involved in differentiation GO:0010770 4 0.014
formation of anatomical boundary GO:0048859 1 0.014
myosin filament organization GO:0031033 138 0.014
regulation of anatomical structure morphogenesis GO:0022603 51 0.014
regulation of cell morphogenesis involved in differentiation GO:0010769 29 0.014
positive regulation of epithelial cell proliferation GO:0050679 1 0.014
positive regulation of response to stimulus GO:0048584 55 0.014
regulation of neuron projection development GO:0010975 31 0.014
phagocytosis engulfment GO:0006911 98 0.014
organonitrogen compound metabolic process GO:1901564 151 0.014
response to endogenous stimulus GO:0009719 33 0.014
positive regulation of transcription from rna polymerase ii promoter in response to salt stress GO:0036251 1 0.014
positive regulation of transcription from rna polymerase ii promoter in response to osmotic stress GO:0061393 1 0.014
membrane invagination GO:0010324 98 0.014
response to acid chemical GO:0001101 4 0.014
gene silencing GO:0016458 143 0.014
positive regulation of transcription from rna polymerase ii promoter in response to stress GO:0036003 2 0.014
single organism membrane fusion GO:0044801 13 0.014
regulation of cell development GO:0060284 49 0.014
carbohydrate derivative metabolic process GO:1901135 141 0.013
positive regulation of protein transport GO:0051222 4 0.013
Mouse
endoderm development GO:0007492 20 0.013
innate immune response GO:0045087 190 0.013
muscle fiber development GO:0048747 2 0.013
posttranscriptional gene silencing GO:0016441 143 0.013
positive regulation of transcription from rna polymerase ii promoter involved in defense response to gram negative bacterium GO:1902097 4 0.013
positive regulation of transcription from rna polymerase ii promoter involved in defense response to fungus GO:1901244 1 0.013
negative regulation of response to stimulus GO:0048585 73 0.013
regulation of cell projection organization GO:0031344 38 0.013
epithelial cell differentiation GO:0030855 17 0.013
positive regulation of stress activated mapk cascade GO:0032874 3 0.013
regulation of gene expression epigenetic GO:0040029 163 0.013
establishment of organelle localization GO:0051656 123 0.013
membrane fusion GO:0061025 16 0.013
protein oligomerization GO:0051259 4 0.013
apical junction assembly GO:0043297 1 0.013
regulation of hormone secretion GO:0046883 2 0.013
cell substrate adhesion GO:0031589 1 0.013
chemical homeostasis GO:0048878 29 0.013
olfactory behavior GO:0042048 27 0.012
cell cell signaling GO:0007267 118 0.012
regulation of cell morphogenesis GO:0022604 40 0.012
positive regulation of nematode larval development GO:0061063 54 0.012
engulfment of apoptotic cell GO:0043652 94 0.012
negative regulation of signaling GO:0023057 61 0.012
negative regulation of neuron differentiation GO:0045665 4 0.012
spindle localization GO:0051653 51 0.012
cellular response to hormone stimulus GO:0032870 14 0.012
positive regulation of vulval development GO:0040026 52 0.012
organic substance catabolic process GO:1901575 294 0.012
regulation of cell death GO:0010941 65 0.012
tissue morphogenesis GO:0048729 65 0.012
Zebrafish Mouse
response to temperature stimulus GO:0009266 66 0.012
regulation of gastrulation GO:0010470 4 0.012
negative regulation of cell communication GO:0010648 61 0.012
cellular hyperosmotic salinity response GO:0071475 1 0.012
epidermal cell differentiation GO:0009913 7 0.012
regulation of nucleocytoplasmic transport GO:0046822 3 0.012
Mouse
single organism catabolic process GO:0044712 129 0.011
synaptic growth at neuromuscular junction GO:0051124 1 0.011
g1 s transition of mitotic cell cycle GO:0000082 2 0.011
rna interference GO:0016246 137 0.011
positive regulation of transcription from rna polymerase ii promoter in response to increased salt GO:0061404 1 0.011
developmental maturation GO:0021700 26 0.011
establishment of spindle localization GO:0051293 51 0.011
regulation of protein metabolic process GO:0051246 81 0.011
mitotic spindle organization GO:0007052 81 0.011
positive regulation of cell migration GO:0030335 3 0.011
establishment of spindle orientation GO:0051294 34 0.011
neuron fate commitment GO:0048663 8 0.011
catabolic process GO:0009056 318 0.011
meiotic cell cycle process GO:1903046 170 0.011
regulation of behavior GO:0050795 97 0.011
regulation of cellular protein metabolic process GO:0032268 75 0.011
negative regulation of bmp signaling pathway GO:0030514 1 0.011
small gtpase mediated signal transduction GO:0007264 32 0.011
regulation of programmed cell death GO:0043067 50 0.011
cell cycle g1 s phase transition GO:0044843 2 0.011
regulation of transcription from rna polymerase ii promoter in response to salt stress GO:0061416 1 0.011
cilium morphogenesis GO:0060271 33 0.011
enzyme linked receptor protein signaling pathway GO:0007167 50 0.011
Fly
response to oxygen containing compound GO:1901700 44 0.011
detection of external stimulus GO:0009581 4 0.011
positive regulation of cell communication GO:0010647 69 0.011
cell growth GO:0016049 44 0.011
cell maturation GO:0048469 26 0.011
cell projection assembly GO:0030031 35 0.011
regulation of mitotic cell cycle GO:0007346 76 0.011
lipid metabolic process GO:0006629 77 0.011
nucleotide catabolic process GO:0009166 77 0.011
regulation of catalytic activity GO:0050790 78 0.011
regulation of chromatin modification GO:1903308 2 0.010
cellular catabolic process GO:0044248 199 0.010
neuron projection extension GO:1990138 37 0.010
cellular protein localization GO:0034613 75 0.010
Mouse
neuron apoptotic process GO:0051402 4 0.010
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.010
response to bacterium GO:0009617 86 0.010
purine nucleoside triphosphate metabolic process GO:0009144 87 0.010
regulation of phosphorus metabolic process GO:0051174 81 0.010
single organism membrane organization GO:0044802 35 0.010
developmental cell growth GO:0048588 39 0.010
negative regulation of gene expression epigenetic GO:0045814 2 0.010
positive regulation of post embryonic development GO:0048582 54 0.010
memory GO:0007613 3 0.010
regulation of phosphate metabolic process GO:0019220 81 0.010
single organism intracellular transport GO:1902582 70 0.010
Mouse
hormone metabolic process GO:0042445 3 0.010
cytokinesis GO:0000910 80 0.010
regulation of transcription from rna polymerase ii promoter in response to osmotic stress GO:0061392 1 0.010
chromosome organization GO:0051276 104 0.010

ref-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.036
nervous system disease DOID:863 0 0.016
cancer DOID:162 0 0.014
disease of cellular proliferation DOID:14566 0 0.014
organ system cancer DOID:0050686 0 0.012