Caenorhabditis elegans

109 known processes

mca-1 (CELE_W09C2.3)

Protein MCA-1

mca-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
aromatic compound biosynthetic process GO:0019438 192 0.390
Human
regulation of nucleic acid templated transcription GO:1903506 165 0.366
Human
rna biosynthetic process GO:0032774 169 0.331
Human
nucleobase containing compound biosynthetic process GO:0034654 184 0.331
Human
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.323
Human
heterocycle biosynthetic process GO:0018130 187 0.316
Human
regulation of rna biosynthetic process GO:2001141 165 0.311
Human
nucleic acid templated transcription GO:0097659 169 0.308
Human
organic substance biosynthetic process GO:1901576 323 0.302
Human
cellular biosynthetic process GO:0044249 315 0.290
Human
biosynthetic process GO:0009058 323 0.289
Human
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.289
Human
regulation of biosynthetic process GO:0009889 189 0.286
Human
regulation of cellular metabolic process GO:0031323 305 0.272
Human
embryo development GO:0009790 3052 0.269
Mouse Worm
gene expression GO:0010467 412 0.268
Human
establishment of localization GO:0051234 1171 0.254
organic cyclic compound biosynthetic process GO:1901362 195 0.245
Human
signaling GO:0023052 401 0.209
Human Mouse
positive regulation of gene expression GO:0010628 112 0.203
regulation of metabolic process GO:0019222 478 0.197
Human
regulation of primary metabolic process GO:0080090 292 0.193
Human
transcription dna templated GO:0006351 168 0.191
Human
organ development GO:0048513 1102 0.187
Zebrafish Mouse Rat
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.186
regulation of cellular biosynthetic process GO:0031326 189 0.184
Human
nucleobase containing compound metabolic process GO:0006139 406 0.183
positive regulation of biosynthetic process GO:0009891 109 0.179
cellular macromolecule biosynthetic process GO:0034645 247 0.175
Human
positive regulation of cellular metabolic process GO:0031325 178 0.169
Human
regulation of transcription dna templated GO:0006355 164 0.166
Human
regulation of nitrogen compound metabolic process GO:0051171 222 0.162
Human
regulation of gene expression GO:0010468 366 0.162
Human
rna metabolic process GO:0016070 228 0.160
Human
macromolecule biosynthetic process GO:0009059 250 0.159
Human
single organism transport GO:0044765 447 0.155
transport GO:0006810 1093 0.154
multicellular organismal aging GO:0010259 812 0.151
nucleic acid metabolic process GO:0090304 299 0.147
Human
gonad development GO:0008406 840 0.143
organonitrogen compound metabolic process GO:1901564 151 0.142
determination of adult lifespan GO:0008340 812 0.141
embryo development ending in birth or egg hatching GO:0009792 2992 0.128
Worm
regulation of macromolecule biosynthetic process GO:0010556 189 0.126
Human
reproductive structure development GO:0048608 850 0.126
regulation of rna metabolic process GO:0051252 173 0.125
Human
negative regulation of biological process GO:0048519 567 0.124
Human Mouse
molting cycle GO:0042303 281 0.118
cellular nitrogen compound biosynthetic process GO:0044271 192 0.115
Human
negative regulation of cellular process GO:0048523 239 0.113
Human
positive regulation of developmental process GO:0051094 408 0.112
Worm
regulation of macromolecule metabolic process GO:0060255 421 0.108
Human
regulation of biological quality GO:0065008 741 0.107
phosphorylation GO:0016310 116 0.102
Human
negative regulation of macromolecule metabolic process GO:0010605 229 0.102
regulation of growth GO:0040008 409 0.101
Worm
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.100
Human
protein modification process GO:0036211 207 0.099
Human
cellular protein modification process GO:0006464 207 0.099
Human
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.095
Human
ion transport GO:0006811 113 0.094
homeostatic process GO:0042592 51 0.094
regulation of multicellular organismal development GO:2000026 317 0.094
positive regulation of rna biosynthetic process GO:1902680 102 0.092
negative regulation of cellular metabolic process GO:0031324 95 0.091
Human
protein metabolic process GO:0019538 422 0.091
Human
cellular response to chemical stimulus GO:0070887 129 0.090
Human
cellular localization GO:0051641 360 0.089
Worm
signal transduction GO:0007165 317 0.087
Human
locomotion GO:0040011 1634 0.087
establishment of localization in cell GO:0051649 318 0.087
Worm
positive regulation of multicellular organismal process GO:0051240 417 0.082
Worm
macromolecule modification GO:0043412 218 0.081
Human
development of primary sexual characteristics GO:0045137 840 0.080
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.080
aging GO:0007568 812 0.077
organ morphogenesis GO:0009887 67 0.075
Mouse
reproductive system development GO:0061458 850 0.075
single organism reproductive process GO:0044702 1196 0.073
cellular protein metabolic process GO:0044267 279 0.072
Human
apoptotic process GO:0006915 478 0.072
regulation of response to stimulus GO:0048583 243 0.070
Human Mouse
negative regulation of multicellular organismal process GO:0051241 236 0.070
Human Mouse
post embryonic development GO:0009791 2152 0.070
Worm
single organism localization GO:1902578 518 0.069
macromolecule localization GO:0033036 771 0.067
response to wounding GO:0009611 4 0.066
behavior GO:0007610 527 0.064
Mouse
lipid localization GO:0010876 573 0.064
regulation of multicellular organismal process GO:0051239 726 0.062
Human Mouse Worm
regulation of phosphorylation GO:0042325 45 0.062
Human
positive regulation of metabolic process GO:0009893 187 0.061
Human
regulation of developmental process GO:0050793 684 0.061
Worm
positive regulation of nucleic acid templated transcription GO:1903508 102 0.061
organelle organization GO:0006996 783 0.060
Mouse
negative regulation of transcription from rna polymerase ii promoter GO:0000122 45 0.060
lipid storage GO:0019915 565 0.060
response to external stimulus GO:0009605 289 0.059
Mouse
positive regulation of rna metabolic process GO:0051254 103 0.058
maintenance of location GO:0051235 580 0.057
carbohydrate derivative metabolic process GO:1901135 141 0.057
endocytosis GO:0006897 819 0.057
Worm
sensory organ morphogenesis GO:0090596 2 0.056
Mouse
developmental growth GO:0048589 412 0.054
Worm
developmental process involved in reproduction GO:0003006 1165 0.054
response to chemical GO:0042221 356 0.053
Human
programmed cell death GO:0012501 500 0.051
cellular response to organic substance GO:0071310 119 0.050
Human
negative regulation of transcription dna templated GO:0045892 53 0.050
regulation of cellular amino acid metabolic process GO:0006521 0 0.050
Human
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.049
Mouse
g protein coupled receptor signaling pathway GO:0007186 46 0.048
Human
regulation of developmental growth GO:0048638 389 0.048
Worm
sex differentiation GO:0007548 909 0.048
negative regulation of cellular biosynthetic process GO:0031327 65 0.047
Human
cell cycle GO:0007049 526 0.046
intracellular signal transduction GO:0035556 96 0.046
Human
growth GO:0040007 562 0.046
Worm
positive regulation of developmental growth GO:0048639 354 0.046
Worm
death GO:0016265 547 0.046
regulation of lipid biosynthetic process GO:0046890 1 0.046
multi organism reproductive process GO:0044703 867 0.046
cell development GO:0048468 696 0.045
Zebrafish Mouse
phosphate containing compound metabolic process GO:0006796 232 0.045
ribonucleoprotein complex assembly GO:0022618 4 0.045
positive regulation of growth GO:0045927 369 0.044
Worm
negative regulation of gene expression GO:0010629 217 0.044
negative regulation of biosynthetic process GO:0009890 65 0.043
Human
skeletal muscle organ development GO:0060538 3 0.043
cell cell signaling GO:0007267 118 0.043
Mouse
vesicle mediated transport GO:0016192 852 0.042
Worm
multi multicellular organism process GO:0044706 390 0.042
axon development GO:0061564 163 0.042
negative regulation of rna metabolic process GO:0051253 53 0.042
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.040
regulation of cellular ketone metabolic process GO:0010565 3 0.040
Human
multi organism reproductive behavior GO:0044705 387 0.039
cell cycle process GO:0022402 482 0.039
response to abiotic stimulus GO:0009628 152 0.039
Human Mouse
regulation of localization GO:0032879 194 0.039
Mouse Worm
negative regulation of metabolic process GO:0009892 240 0.039
Human
phosphorus metabolic process GO:0006793 232 0.039
single organism behavior GO:0044708 83 0.039
single organism signaling GO:0044700 401 0.039
Human Mouse
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.038
secretion by cell GO:0032940 138 0.038
Worm
generation of neurons GO:0048699 235 0.038
Human Zebrafish Mouse
negative regulation of rna biosynthetic process GO:1902679 53 0.038
cell surface receptor signaling pathway GO:0007166 149 0.038
Human
carboxylic acid metabolic process GO:0019752 34 0.038
Human
positive regulation of multicellular organism growth GO:0040018 352 0.037
Worm
system process GO:0003008 136 0.037
Human Zebrafish Mouse
chemical homeostasis GO:0048878 29 0.037
meiotic chromosome segregation GO:0045132 139 0.037
dauer larval development GO:0040024 92 0.037
cell death GO:0008219 547 0.036
regulation of cellular amine metabolic process GO:0033238 0 0.036
Human
axon guidance GO:0007411 82 0.036
regulation of lipid metabolic process GO:0019216 4 0.035
muscle tissue development GO:0060537 1 0.035
multicellular organism growth GO:0035264 385 0.035
Worm
small molecule metabolic process GO:0044281 186 0.035
regulation of phosphate metabolic process GO:0019220 81 0.034
Human
positive regulation of transcription dna templated GO:0045893 102 0.034
synaptic transmission GO:0007268 106 0.034
Mouse
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.034
regulation of multicellular organism growth GO:0040014 373 0.033
Worm
negative regulation of nucleic acid templated transcription GO:1903507 53 0.033
multi organism behavior GO:0051705 389 0.033
cellular amine metabolic process GO:0044106 15 0.033
Human
organic acid metabolic process GO:0006082 47 0.032
Human
purine ribonucleotide metabolic process GO:0009150 95 0.032
regulation of cell cycle process GO:0010564 145 0.032
body morphogenesis GO:0010171 620 0.032
anion transport GO:0006820 30 0.032
positive regulation of macromolecule metabolic process GO:0010604 149 0.031
Human
regulation of signaling GO:0023051 172 0.031
Human Mouse
response to nutrient levels GO:0031667 35 0.031
reproductive behavior GO:0019098 387 0.030
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.030
positive regulation of signal transduction GO:0009967 40 0.029
positive regulation of cellular biosynthetic process GO:0031328 109 0.029
secretion GO:0046903 147 0.029
Mouse Worm
neuromuscular junction development GO:0007528 2 0.029
tissue development GO:0009888 112 0.029
Zebrafish Mouse Rat
organelle fission GO:0048285 363 0.029
oxoacid metabolic process GO:0043436 47 0.029
Human
hermaphrodite genitalia development GO:0040035 734 0.029
catabolic process GO:0009056 318 0.029
genitalia development GO:0048806 741 0.028
cellular response to abiotic stimulus GO:0071214 4 0.028
regulation of locomotion GO:0040012 161 0.028
Worm
macromolecular complex subunit organization GO:0043933 320 0.028
regulation of synapse assembly GO:0051963 2 0.028
regulation of post embryonic development GO:0048580 260 0.028
regulation of meiotic cell cycle GO:0051445 136 0.027
receptor mediated endocytosis GO:0006898 715 0.027
regulation of molecular function GO:0065009 89 0.027
Human
response to mechanical stimulus GO:0009612 28 0.027
Mouse
response to acid chemical GO:0001101 4 0.027
Human
histone modification GO:0016570 30 0.027
neuron differentiation GO:0030182 217 0.027
Human Zebrafish Mouse
chemosensory behavior GO:0007635 33 0.026
meiotic cell cycle GO:0051321 335 0.026
ribose phosphate metabolic process GO:0019693 99 0.026
neuron development GO:0048666 199 0.026
Zebrafish Mouse
carbohydrate derivative catabolic process GO:1901136 82 0.025
positive regulation of cellular process GO:0048522 332 0.025
Human
sexual reproduction GO:0019953 546 0.025
multicellular organismal reproductive behavior GO:0033057 384 0.025
regulation of nucleotide metabolic process GO:0006140 37 0.025
single organism organelle organization GO:1902589 501 0.024
nervous system development GO:0007399 253 0.024
Human Zebrafish Mouse Rat
regulation of purine nucleotide metabolic process GO:1900542 37 0.024
amine metabolic process GO:0009308 15 0.024
Human
regulation of synaptic transmission GO:0050804 34 0.024
Mouse
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.024
cellular response to stress GO:0033554 162 0.024
protein phosphorylation GO:0006468 85 0.023
Human
positive regulation of neuron differentiation GO:0045666 4 0.023
positive regulation of cell communication GO:0010647 69 0.023
cytoskeleton organization GO:0007010 339 0.023
cell migration GO:0016477 306 0.023
transcription from rna polymerase ii promoter GO:0006366 149 0.023
Human
epithelial tube morphogenesis GO:0060562 1 0.022
nucleotide metabolic process GO:0009117 108 0.022
defense response GO:0006952 296 0.022
regulation of cellular component organization GO:0051128 248 0.022
Worm
vulval development GO:0040025 333 0.022
cation transport GO:0006812 78 0.022
fertilization GO:0009566 63 0.021
pronuclear migration GO:0035046 51 0.021
bmp signaling pathway GO:0030509 3 0.021
nitrogen compound transport GO:0071705 49 0.021
regulation of intracellular signal transduction GO:1902531 77 0.021
Human
embryonic morphogenesis GO:0048598 152 0.021
Mouse
positive regulation of response to stimulus GO:0048584 55 0.020
calcium mediated signaling GO:0019722 3 0.020
Human
synaptic growth at neuromuscular junction GO:0051124 1 0.020
peptidyl amino acid modification GO:0018193 58 0.020
Human
chromatin modification GO:0016568 32 0.020
negative regulation of developmental process GO:0051093 227 0.020
regulation of signal transduction GO:0009966 135 0.020
Human
single organism biosynthetic process GO:0044711 91 0.020
Human
single organism intracellular transport GO:1902582 70 0.020
response to inorganic substance GO:0010035 50 0.020
Human
tube development GO:0035295 126 0.020
cell type specific apoptotic process GO:0097285 4 0.020
ribosome biogenesis GO:0042254 4 0.020
regulation of catalytic activity GO:0050790 78 0.019
Human
regulation of striated muscle contraction GO:0006942 4 0.019
head development GO:0060322 1 0.019
Mouse Rat
regulation of catabolic process GO:0009894 57 0.019
Human
monovalent inorganic cation transport GO:0015672 33 0.019
Mouse
regulation of cell cycle GO:0051726 194 0.019
regulation of ion transport GO:0043269 39 0.019
Mouse
regulation of cytoplasmic transport GO:1903649 3 0.019
autophagy GO:0006914 29 0.019
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.019
post embryonic organ development GO:0048569 336 0.019
ion transmembrane transport GO:0034220 91 0.019
lipid biosynthetic process GO:0008610 28 0.018
cellular ketone metabolic process GO:0042180 14 0.018
Human
defense response to bacterium GO:0042742 86 0.018
oviposition GO:0018991 364 0.018
organophosphate metabolic process GO:0019637 125 0.018
immune response GO:0006955 192 0.018
regulation of nucleocytoplasmic transport GO:0046822 3 0.018
cellular nitrogen compound catabolic process GO:0044270 119 0.018
gamete generation GO:0007276 461 0.018
multicellular organism reproduction GO:0032504 819 0.018
regulation of hormone secretion GO:0046883 2 0.018
negative regulation of response to stimulus GO:0048585 73 0.018
Human Mouse
chromosome segregation GO:0007059 180 0.018
positive regulation of intracellular transport GO:0032388 2 0.018
regulation of cellular component size GO:0032535 40 0.017
Mouse
regulation of phosphorus metabolic process GO:0051174 81 0.017
Human
hormone transport GO:0009914 2 0.017
peptidyl serine phosphorylation GO:0018105 20 0.017
Human
regulation of cell size GO:0008361 30 0.017
Mouse
positive regulation of signaling GO:0023056 66 0.017
positive regulation of organ growth GO:0046622 4 0.016
regulation of organelle organization GO:0033043 164 0.016
small gtpase mediated signal transduction GO:0007264 32 0.016
multicellular organismal reproductive process GO:0048609 815 0.016
intracellular receptor signaling pathway GO:0030522 2 0.016
cell growth GO:0016049 44 0.016
dna metabolic process GO:0006259 74 0.016
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.016
organic substance transport GO:0071702 113 0.016
response to organic substance GO:0010033 131 0.016
Human
meiotic nuclear division GO:0007126 300 0.016
mitotic cell cycle process GO:1903047 194 0.016
ribonucleotide metabolic process GO:0009259 99 0.016
purine nucleotide metabolic process GO:0006163 95 0.016
ribonucleoside triphosphate metabolic process GO:0009199 87 0.016
muscle fiber development GO:0048747 2 0.015
neuron projection development GO:0031175 187 0.015
regulation of cellular localization GO:0060341 42 0.015
dopamine receptor signaling pathway GO:0007212 11 0.015
cell morphogenesis involved in differentiation GO:0000904 112 0.015
Mouse
establishment of protein localization to membrane GO:0090150 3 0.015
male sex differentiation GO:0046661 86 0.015
carbohydrate metabolic process GO:0005975 34 0.015
aromatic compound catabolic process GO:0019439 116 0.015
cuticle development GO:0042335 100 0.015
response to oxygen containing compound GO:1901700 44 0.015
Human
positive regulation of neurogenesis GO:0050769 4 0.014
cellular response to inorganic substance GO:0071241 3 0.014
ribonucleoside monophosphate metabolic process GO:0009161 45 0.014
cell part morphogenesis GO:0032990 152 0.014
covalent chromatin modification GO:0016569 30 0.014
negative regulation of nematode larval development GO:0061064 208 0.014
tube morphogenesis GO:0035239 79 0.014
response to extracellular stimulus GO:0009991 38 0.014
organelle assembly GO:0070925 214 0.014
cellular component morphogenesis GO:0032989 318 0.014
Mouse
digestive tract development GO:0048565 122 0.014
atp metabolic process GO:0046034 42 0.014
chemotaxis GO:0006935 120 0.014
cellular amino acid metabolic process GO:0006520 15 0.014
Human
peptidyl serine modification GO:0018209 20 0.014
Human
regulation of meiosis GO:0040020 94 0.014
cell proliferation GO:0008283 116 0.013
cellular component movement GO:0006928 388 0.013
cellular response to oxygen containing compound GO:1901701 21 0.013
Human
lipid metabolic process GO:0006629 77 0.013
regulation of behavior GO:0050795 97 0.013
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.013
digestive system development GO:0055123 122 0.013
regulation of cellular carbohydrate metabolic process GO:0010675 2 0.013
regeneration GO:0031099 4 0.013
ribonucleotide catabolic process GO:0009261 75 0.013
cell projection organization GO:0030030 231 0.013
Mouse
negative regulation of neurogenesis GO:0050768 4 0.013
regulation of cell communication GO:0010646 176 0.013
Human Mouse
rrna metabolic process GO:0016072 3 0.013
regulation of protein targeting GO:1903533 3 0.012
positive regulation of intracellular signal transduction GO:1902533 24 0.012
germ line sex determination GO:0018992 51 0.012
regulation of vulval development GO:0040028 248 0.012
oocyte construction GO:0007308 2 0.012
muscle cell development GO:0055001 158 0.012
protein complex biogenesis GO:0070271 186 0.012
purine containing compound metabolic process GO:0072521 95 0.012
actin cytoskeleton organization GO:0030036 184 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.012
necrotic cell death GO:0070265 29 0.012
actomyosin structure organization GO:0031032 154 0.012
cellular catabolic process GO:0044248 199 0.012
cellular component assembly GO:0022607 293 0.012
cell substrate adhesion GO:0031589 1 0.012
nucleotide catabolic process GO:0009166 77 0.012
positive regulation of chromosome organization GO:2001252 2 0.011
negative regulation of bmp signaling pathway GO:0030514 1 0.011
negative regulation of signal transduction GO:0009968 60 0.011
Human
nucleoside phosphate metabolic process GO:0006753 108 0.011
chromosome organization GO:0051276 104 0.011
regulation of bmp signaling pathway GO:0030510 3 0.011
defense response to gram negative bacterium GO:0050829 64 0.011
regulation of response to wounding GO:1903034 1 0.011
hormone secretion GO:0046879 2 0.011
regulation of muscle cell differentiation GO:0051147 1 0.011
protein localization GO:0008104 205 0.011
regulation of carbohydrate metabolic process GO:0006109 2 0.011
chromatin assembly or disassembly GO:0006333 1 0.011
regulation of protein metabolic process GO:0051246 81 0.011
Human
regulation of anatomical structure morphogenesis GO:0022603 51 0.011
regulation of gastrulation GO:0010470 4 0.011
single fertilization GO:0007338 61 0.011
anatomical structure formation involved in morphogenesis GO:0048646 250 0.011
Mouse
neuron projection extension GO:1990138 37 0.011
regulation of protein stability GO:0031647 3 0.010
cell fate commitment involved in formation of primary germ layer GO:0060795 33 0.010
cyclic nucleotide metabolic process GO:0009187 2 0.010
Mouse
muscle cell differentiation GO:0042692 171 0.010
intracellular transport GO:0046907 77 0.010
cellular component assembly involved in morphogenesis GO:0010927 183 0.010
neuron projection morphogenesis GO:0048812 114 0.010
regulation of cell proliferation GO:0042127 105 0.010
posttranscriptional regulation of gene expression GO:0010608 166 0.010
cellular protein complex assembly GO:0043623 178 0.010
locomotory behavior GO:0007626 40 0.010
Mouse

mca-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.035
Human
nervous system disease DOID:863 0 0.014
Human
disease of cellular proliferation DOID:14566 0 0.012