Caenorhabditis elegans

19 known processes

zig-4 (CELE_C09C7.1)

Protein ZIG-4

zig-4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development ending in birth or egg hatching GO:0009792 2992 0.210
Worm
embryo development GO:0009790 3052 0.140
Worm
transport GO:0006810 1093 0.121
post embryonic development GO:0009791 2152 0.107
Worm
negative regulation of biological process GO:0048519 567 0.099
Fly
establishment of localization GO:0051234 1171 0.098
locomotion GO:0040011 1634 0.098
multicellular organismal reproductive process GO:0048609 815 0.097
single organism reproductive process GO:0044702 1196 0.089
developmental process involved in reproduction GO:0003006 1165 0.089
multicellular organismal aging GO:0010259 812 0.083
Fly
multi organism reproductive process GO:0044703 867 0.080
macromolecule localization GO:0033036 771 0.071
organ development GO:0048513 1102 0.071
determination of adult lifespan GO:0008340 812 0.067
Fly
single organism localization GO:1902578 518 0.064
regulation of multicellular organismal process GO:0051239 726 0.064
reproductive system development GO:0061458 850 0.062
gonad development GO:0008406 840 0.062
multicellular organism reproduction GO:0032504 819 0.060
maintenance of location GO:0051235 580 0.059
development of primary sexual characteristics GO:0045137 840 0.059
single organism transport GO:0044765 447 0.058
cell death GO:0008219 547 0.058
receptor mediated endocytosis GO:0006898 715 0.058
genitalia development GO:0048806 741 0.057
vesicle mediated transport GO:0016192 852 0.057
lipid storage GO:0019915 565 0.055
lipid localization GO:0010876 573 0.055
regulation of biological quality GO:0065008 741 0.054
signaling GO:0023052 401 0.053
Fly
head development GO:0060322 1 0.052
regulation of developmental process GO:0050793 684 0.052
positive regulation of developmental process GO:0051094 408 0.052
reproductive structure development GO:0048608 850 0.050
sex differentiation GO:0007548 909 0.050
regulation of macromolecule metabolic process GO:0060255 421 0.050
programmed cell death GO:0012501 500 0.050
death GO:0016265 547 0.049
hermaphrodite genitalia development GO:0040035 734 0.048
growth GO:0040007 562 0.048
cell cycle process GO:0022402 482 0.047
multi multicellular organism process GO:0044706 390 0.047
endocytosis GO:0006897 819 0.047
cell development GO:0048468 696 0.047
multi organism reproductive behavior GO:0044705 387 0.046
cellular component movement GO:0006928 388 0.044
establishment of localization in cell GO:0051649 318 0.043
aging GO:0007568 812 0.043
Fly
cellular biosynthetic process GO:0044249 315 0.040
behavior GO:0007610 527 0.040
multi organism behavior GO:0051705 389 0.040
single organism signaling GO:0044700 401 0.039
Fly
regulation of macromolecule biosynthetic process GO:0010556 189 0.039
multicellular organismal reproductive behavior GO:0033057 384 0.038
organelle organization GO:0006996 783 0.037
positive regulation of multicellular organismal process GO:0051240 417 0.037
regulation of metabolic process GO:0019222 478 0.037
cell cycle GO:0007049 526 0.037
reproductive behavior GO:0019098 387 0.036
regulation of post embryonic development GO:0048580 260 0.035
generation of neurons GO:0048699 235 0.034
positive regulation of developmental growth GO:0048639 354 0.034
regulation of multicellular organismal development GO:2000026 317 0.034
regulation of multicellular organism growth GO:0040014 373 0.034
organic substance biosynthetic process GO:1901576 323 0.034
post embryonic organ development GO:0048569 336 0.034
nucleobase containing compound metabolic process GO:0006139 406 0.033
regulation of nitrogen compound metabolic process GO:0051171 222 0.033
developmental growth GO:0048589 412 0.032
sexual reproduction GO:0019953 546 0.032
regulation of vulval development GO:0040028 248 0.032
gene expression GO:0010467 412 0.032
response to chemical GO:0042221 356 0.032
Fly
apoptotic process GO:0006915 478 0.032
regulation of developmental growth GO:0048638 389 0.031
heterocycle biosynthetic process GO:0018130 187 0.031
cellular component biogenesis GO:0044085 297 0.031
positive regulation of growth GO:0045927 369 0.030
positive regulation of multicellular organism growth GO:0040018 352 0.030
negative regulation of post embryonic development GO:0048581 208 0.030
regulation of gene expression GO:0010468 366 0.030
localization of cell GO:0051674 313 0.030
body morphogenesis GO:0010171 620 0.030
protein metabolic process GO:0019538 422 0.029
cellular component assembly GO:0022607 293 0.029
multicellular organism growth GO:0035264 385 0.029
oviposition GO:0018991 364 0.029
nucleic acid metabolic process GO:0090304 299 0.029
regulation of nematode larval development GO:0061062 260 0.029
biosynthetic process GO:0009058 323 0.029
macromolecular complex subunit organization GO:0043933 320 0.028
negative regulation of gene expression GO:0010629 217 0.028
vulval development GO:0040025 333 0.028
positive regulation of cellular process GO:0048522 332 0.028
Fly
response to external stimulus GO:0009605 289 0.027
regulation of growth GO:0040008 409 0.027
gamete generation GO:0007276 461 0.027
cellular localization GO:0051641 360 0.027
epithelial tube morphogenesis GO:0060562 1 0.027
regulation of primary metabolic process GO:0080090 292 0.026
negative regulation of metabolic process GO:0009892 240 0.026
negative regulation of multicellular organismal process GO:0051241 236 0.026
cell motility GO:0048870 313 0.025
female gamete generation GO:0007292 254 0.025
sensory organ morphogenesis GO:0090596 2 0.025
neuron development GO:0048666 199 0.025
cellular macromolecule biosynthetic process GO:0034645 247 0.025
regulation of signaling GO:0023051 172 0.024
Fly
neurogenesis GO:0022008 236 0.024
single organism organelle organization GO:1902589 501 0.024
germ cell development GO:0007281 351 0.024
regulation of biosynthetic process GO:0009889 189 0.024
protein complex subunit organization GO:0071822 280 0.023
neuron differentiation GO:0030182 217 0.023
response to wounding GO:0009611 4 0.023
organic cyclic compound biosynthetic process GO:1901362 195 0.023
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.023
negative regulation of macromolecule metabolic process GO:0010605 229 0.023
molting cycle GO:0042303 281 0.022
protein localization GO:0008104 205 0.022
signal transduction GO:0007165 317 0.022
Fly
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.022
anatomical structure formation involved in morphogenesis GO:0048646 250 0.021
rna metabolic process GO:0016070 228 0.021
oogenesis GO:0048477 229 0.021
small molecule metabolic process GO:0044281 186 0.021
catabolic process GO:0009056 318 0.021
nucleic acid templated transcription GO:0097659 169 0.021
negative regulation of cellular process GO:0048523 239 0.021
Fly
transcription from rna polymerase ii promoter GO:0006366 149 0.021
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.020
regulation of localization GO:0032879 194 0.020
cell division GO:0051301 262 0.020
transcription dna templated GO:0006351 168 0.020
system process GO:0003008 136 0.019
cytoskeleton organization GO:0007010 339 0.019
cellular nitrogen compound biosynthetic process GO:0044271 192 0.019
negative regulation of developmental process GO:0051093 227 0.019
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.019
regulation of cellular metabolic process GO:0031323 305 0.019
cellular component morphogenesis GO:0032989 318 0.019
cellular protein metabolic process GO:0044267 279 0.018
secretion GO:0046903 147 0.018
aromatic compound biosynthetic process GO:0019438 192 0.018
regulation of rna metabolic process GO:0051252 173 0.018
organonitrogen compound metabolic process GO:1901564 151 0.018
macromolecule biosynthetic process GO:0009059 250 0.018
negative regulation of vulval development GO:0040027 206 0.017
neuron projection development GO:0031175 187 0.017
macromolecule modification GO:0043412 218 0.017
cell type specific apoptotic process GO:0097285 4 0.017
cell projection organization GO:0030030 231 0.017
response to organic substance GO:0010033 131 0.017
Fly
nervous system development GO:0007399 253 0.016
regulation of cellular biosynthetic process GO:0031326 189 0.016
regulation of cell communication GO:0010646 176 0.016
Fly
canonical wnt signaling pathway GO:0060070 3 0.016
negative regulation of nematode larval development GO:0061064 208 0.016
protein complex biogenesis GO:0070271 186 0.016
oxoacid metabolic process GO:0043436 47 0.016
regulation of response to stimulus GO:0048583 243 0.016
Fly
organelle fission GO:0048285 363 0.016
regulation of rna biosynthetic process GO:2001141 165 0.016
regulation of cellular component organization GO:0051128 248 0.016
regulation of nucleic acid templated transcription GO:1903506 165 0.016
establishment of organelle localization GO:0051656 123 0.016
dauer larval development GO:0040024 92 0.016
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.016
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.015
phagocytosis engulfment GO:0006911 98 0.015
regulation of organelle organization GO:0033043 164 0.015
regulation of epithelial cell proliferation GO:0050678 1 0.015
regulation of cell cycle GO:0051726 194 0.015
organic substance transport GO:0071702 113 0.015
regulation of transcription dna templated GO:0006355 164 0.015
cellular protein complex assembly GO:0043623 178 0.015
cellular protein modification process GO:0006464 207 0.015
response to temperature stimulus GO:0009266 66 0.015
apoptotic cell clearance GO:0043277 111 0.015
organic acid metabolic process GO:0006082 47 0.015
rna biosynthetic process GO:0032774 169 0.015
protein complex assembly GO:0006461 186 0.015
positive regulation of cellular metabolic process GO:0031325 178 0.015
membrane invagination GO:0010324 98 0.015
regulation of cytoplasmic transport GO:1903649 3 0.014
macromolecular complex assembly GO:0065003 193 0.014
muscle organ morphogenesis GO:0048644 4 0.014
meiotic nuclear division GO:0007126 300 0.014
phosphate containing compound metabolic process GO:0006796 232 0.014
phosphorus metabolic process GO:0006793 232 0.014
tube development GO:0035295 126 0.014
cell migration GO:0016477 306 0.014
regulation of cellular ketone metabolic process GO:0010565 3 0.014
organic substance catabolic process GO:1901575 294 0.014
skeletal muscle organ development GO:0060538 3 0.014
phagocytosis GO:0006909 115 0.014
meiotic cell cycle GO:0051321 335 0.014
carboxylic acid metabolic process GO:0019752 34 0.013
regulation of reproductive process GO:2000241 66 0.013
digestive system development GO:0055123 122 0.013
response to other organism GO:0051707 101 0.013
organelle localization GO:0051640 127 0.013
cellular macromolecular complex assembly GO:0034622 184 0.013
cellular response to stress GO:0033554 162 0.013
defense response GO:0006952 296 0.013
striated muscle cell differentiation GO:0051146 158 0.013
cellular component assembly involved in morphogenesis GO:0010927 183 0.013
regulation of gene expression epigenetic GO:0040029 163 0.013
regulation of multi organism process GO:0043900 69 0.013
regulation of locomotion GO:0040012 161 0.013
regulation of nucleocytoplasmic transport GO:0046822 3 0.013
intracellular signal transduction GO:0035556 96 0.013
muscle tissue development GO:0060537 1 0.013
secretion by cell GO:0032940 138 0.013
regulation of behavior GO:0050795 97 0.013
engulfment of apoptotic cell GO:0043652 94 0.012
axon development GO:0061564 163 0.012
myosin filament organization GO:0031033 138 0.012
positive regulation of metabolic process GO:0009893 187 0.012
positive regulation of epithelial cell proliferation GO:0050679 1 0.012
myosin filament assembly GO:0031034 138 0.012
single organism biosynthetic process GO:0044711 91 0.012
organelle assembly GO:0070925 214 0.012
regulation of organ morphogenesis GO:2000027 4 0.012
actin filament based process GO:0030029 191 0.012
protein modification process GO:0036211 207 0.012
muscle structure development GO:0061061 191 0.012
response to abiotic stimulus GO:0009628 152 0.012
inductive cell migration GO:0040039 145 0.012
tissue development GO:0009888 112 0.012
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.012
muscle fiber development GO:0048747 2 0.012
striated muscle cell development GO:0055002 157 0.012
actin cytoskeleton organization GO:0030036 184 0.012
regulation of apoptotic signaling pathway GO:2001233 1 0.012
gene silencing by rna GO:0031047 143 0.012
cellular response to chemical stimulus GO:0070887 129 0.012
Fly
cytokinesis GO:0000910 80 0.012
macromolecule catabolic process GO:0009057 202 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.012
posttranscriptional gene silencing GO:0016441 143 0.011
rrna processing GO:0006364 3 0.011
rna interference GO:0016246 137 0.011
cell part morphogenesis GO:0032990 152 0.011
muscle cell development GO:0055001 158 0.011
cellular amino acid metabolic process GO:0006520 15 0.011
cellular response to abiotic stimulus GO:0071214 4 0.011
axonal fasciculation GO:0007413 79 0.011
cellular catabolic process GO:0044248 199 0.011
digestive tract development GO:0048565 122 0.011
posttranscriptional gene silencing by rna GO:0035194 143 0.011
regulation of cellular amine metabolic process GO:0033238 0 0.011
negative regulation of transcription from rna polymerase ii promoter GO:0000122 45 0.011
bmp signaling pathway GO:0030509 3 0.011
regulation of cell cycle process GO:0010564 145 0.011
neuron recognition GO:0008038 83 0.011
regulation of cell division GO:0051302 142 0.011
carbohydrate derivative metabolic process GO:1901135 141 0.011
microtubule based process GO:0007017 182 0.011
neurological system process GO:0050877 53 0.011
positive regulation of intracellular transport GO:0032388 2 0.011
cell morphogenesis involved in differentiation GO:0000904 112 0.011
muscle cell differentiation GO:0042692 171 0.011
mitotic cell cycle process GO:1903047 194 0.011
regulation of protein targeting GO:1903533 3 0.011
regulation of bmp signaling pathway GO:0030510 3 0.011
ion transport GO:0006811 113 0.011
embryonic morphogenesis GO:0048598 152 0.011
response to endoplasmic reticulum stress GO:0034976 71 0.011
protein oligomerization GO:0051259 4 0.010
neuromuscular junction development GO:0007528 2 0.010
striated muscle myosin thick filament assembly GO:0071688 138 0.010
regulation of protein import into nucleus GO:0042306 3 0.010
epithelial cell proliferation GO:0050673 1 0.010
cellular amine metabolic process GO:0044106 15 0.010
cell morphogenesis GO:0000902 163 0.010
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.010
regulation of signal transduction GO:0009966 135 0.010
Fly
chemotaxis GO:0006935 120 0.010

zig-4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.023
nervous system disease DOID:863 0 0.012
cancer DOID:162 0 0.010
disease of cellular proliferation DOID:14566 0 0.010
organ system cancer DOID:0050686 0 0.010