Caenorhabditis elegans

43 known processes

rle-1 (CELE_M142.6)

Protein RLE-1

rle-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development GO:0009790 3052 0.295
embryo development ending in birth or egg hatching GO:0009792 2992 0.288
post embryonic development GO:0009791 2152 0.270
locomotion GO:0040011 1634 0.132
development of primary sexual characteristics GO:0045137 840 0.118
multicellular organism reproduction GO:0032504 819 0.114
organelle organization GO:0006996 783 0.111
Mouse
oviposition GO:0018991 364 0.105
single organism reproductive process GO:0044702 1196 0.104
developmental process involved in reproduction GO:0003006 1165 0.092
organ development GO:0048513 1102 0.089
Mouse
multicellular organismal reproductive process GO:0048609 815 0.088
multi organism reproductive process GO:0044703 867 0.085
regulation of multicellular organismal process GO:0051239 726 0.084
Mouse
vesicle mediated transport GO:0016192 852 0.084
gene expression GO:0010467 412 0.080
Mouse
hermaphrodite genitalia development GO:0040035 734 0.079
single organism organelle organization GO:1902589 501 0.079
gonad development GO:0008406 840 0.074
body morphogenesis GO:0010171 620 0.074
nucleobase containing compound metabolic process GO:0006139 406 0.074
Mouse
macromolecule localization GO:0033036 771 0.072
regulation of cellular metabolic process GO:0031323 305 0.072
regulation of biological quality GO:0065008 741 0.071
Mouse
aging GO:0007568 812 0.070
reproductive structure development GO:0048608 850 0.070
genitalia development GO:0048806 741 0.070
determination of adult lifespan GO:0008340 812 0.069
death GO:0016265 547 0.067
sex differentiation GO:0007548 909 0.067
establishment of localization GO:0051234 1171 0.066
cell death GO:0008219 547 0.065
cellular protein metabolic process GO:0044267 279 0.065
multicellular organism growth GO:0035264 385 0.064
reproductive system development GO:0061458 850 0.064
multicellular organismal aging GO:0010259 812 0.064
cell cycle GO:0007049 526 0.064
regulation of gene expression GO:0010468 366 0.064
Mouse
receptor mediated endocytosis GO:0006898 715 0.063
growth GO:0040007 562 0.062
regulation of developmental process GO:0050793 684 0.061
Mouse
regulation of macromolecule metabolic process GO:0060255 421 0.060
Mouse
maintenance of location GO:0051235 580 0.060
multicellular organismal reproductive behavior GO:0033057 384 0.060
regulation of growth GO:0040008 409 0.059
transport GO:0006810 1093 0.059
single organism localization GO:1902578 518 0.058
cell development GO:0048468 696 0.057
endocytosis GO:0006897 819 0.057
protein metabolic process GO:0019538 422 0.056
signaling GO:0023052 401 0.055
Mouse
lipid storage GO:0019915 565 0.055
lipid localization GO:0010876 573 0.055
multi multicellular organism process GO:0044706 390 0.055
multi organism reproductive behavior GO:0044705 387 0.055
germ cell development GO:0007281 351 0.053
reproductive behavior GO:0019098 387 0.052
negative regulation of vulval development GO:0040027 206 0.051
organic substance biosynthetic process GO:1901576 323 0.051
multi organism behavior GO:0051705 389 0.050
regulation of cellular component organization GO:0051128 248 0.050
cellular component movement GO:0006928 388 0.050
programmed cell death GO:0012501 500 0.050
behavior GO:0007610 527 0.050
apoptotic process GO:0006915 478 0.048
single organism signaling GO:0044700 401 0.048
Mouse
cell motility GO:0048870 313 0.046
cellular localization GO:0051641 360 0.046
macromolecular complex subunit organization GO:0043933 320 0.045
Mouse
vulval development GO:0040025 333 0.045
localization of cell GO:0051674 313 0.045
positive regulation of growth GO:0045927 369 0.044
post embryonic organ development GO:0048569 336 0.043
rna metabolic process GO:0016070 228 0.043
Mouse
nucleobase containing compound biosynthetic process GO:0034654 184 0.043
cytoskeleton organization GO:0007010 339 0.043
muscle tissue development GO:0060537 1 0.042
biosynthetic process GO:0009058 323 0.042
regulation of metabolic process GO:0019222 478 0.042
Mouse
cellular biosynthetic process GO:0044249 315 0.042
positive regulation of developmental growth GO:0048639 354 0.042
negative regulation of macromolecule metabolic process GO:0010605 229 0.041
negative regulation of biological process GO:0048519 567 0.041
Mouse
microtubule based process GO:0007017 182 0.041
regulation of developmental growth GO:0048638 389 0.040
positive regulation of developmental process GO:0051094 408 0.040
regulation of nitrogen compound metabolic process GO:0051171 222 0.040
positive regulation of metabolic process GO:0009893 187 0.039
developmental growth GO:0048589 412 0.039
negative regulation of nematode larval development GO:0061064 208 0.039
positive regulation of multicellular organism growth GO:0040018 352 0.039
cell cycle process GO:0022402 482 0.038
positive regulation of multicellular organismal process GO:0051240 417 0.038
regulation of primary metabolic process GO:0080090 292 0.038
head development GO:0060322 1 0.038
negative regulation of post embryonic development GO:0048581 208 0.038
regulation of organelle organization GO:0033043 164 0.037
cellular nitrogen compound biosynthetic process GO:0044271 192 0.037
heterocycle biosynthetic process GO:0018130 187 0.037
protein complex subunit organization GO:0071822 280 0.037
rna biosynthetic process GO:0032774 169 0.037
regulation of multicellular organism growth GO:0040014 373 0.037
response to external stimulus GO:0009605 289 0.036
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.036
skeletal muscle organ development GO:0060538 3 0.036
negative regulation of metabolic process GO:0009892 240 0.036
positive regulation of macromolecule metabolic process GO:0010604 149 0.036
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.036
defense response GO:0006952 296 0.035
cell migration GO:0016477 306 0.034
negative regulation of gene expression GO:0010629 217 0.034
small molecule metabolic process GO:0044281 186 0.034
signal transduction GO:0007165 317 0.034
Mouse
protein localization GO:0008104 205 0.034
regulation of gene expression epigenetic GO:0040029 163 0.034
protein modification process GO:0036211 207 0.034
regulation of nematode larval development GO:0061062 260 0.033
nucleic acid metabolic process GO:0090304 299 0.033
Mouse
regulation of multicellular organismal development GO:2000026 317 0.033
Mouse
gamete generation GO:0007276 461 0.033
regulation of vulval development GO:0040028 248 0.033
cellular component morphogenesis GO:0032989 318 0.032
nervous system development GO:0007399 253 0.032
catabolic process GO:0009056 318 0.032
aromatic compound biosynthetic process GO:0019438 192 0.032
immune response GO:0006955 192 0.032
Mouse
regulation of cellular biosynthetic process GO:0031326 189 0.032
macromolecule biosynthetic process GO:0009059 250 0.032
positive regulation of nucleic acid templated transcription GO:1903508 102 0.031
single organism transport GO:0044765 447 0.031
transcription dna templated GO:0006351 168 0.030
cellular component biogenesis GO:0044085 297 0.030
Mouse
macromolecule catabolic process GO:0009057 202 0.030
cell division GO:0051301 262 0.030
sexual reproduction GO:0019953 546 0.030
molting cycle GO:0042303 281 0.030
cellular component assembly GO:0022607 293 0.029
Mouse
positive regulation of cellular biosynthetic process GO:0031328 109 0.029
regulation of protein metabolic process GO:0051246 81 0.029
organelle localization GO:0051640 127 0.029
negative regulation of developmental process GO:0051093 227 0.029
Mouse
muscle cell differentiation GO:0042692 171 0.029
response to wounding GO:0009611 4 0.029
anatomical structure formation involved in morphogenesis GO:0048646 250 0.029
cellular macromolecule biosynthetic process GO:0034645 247 0.028
regulation of rna metabolic process GO:0051252 173 0.028
striated muscle cell development GO:0055002 157 0.028
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.028
organelle fission GO:0048285 363 0.028
regulation of cell cycle GO:0051726 194 0.028
regulation of biosynthetic process GO:0009889 189 0.028
cellular protein complex assembly GO:0043623 178 0.027
striated muscle cell differentiation GO:0051146 158 0.027
response to abiotic stimulus GO:0009628 152 0.027
regulation of post embryonic development GO:0048580 260 0.027
cellular response to stress GO:0033554 162 0.027
negative regulation of cellular process GO:0048523 239 0.027
Mouse
muscle structure development GO:0061061 191 0.027
macromolecule modification GO:0043412 218 0.026
transcription from rna polymerase ii promoter GO:0006366 149 0.026
muscle cell development GO:0055001 158 0.026
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.026
negative regulation of multicellular organismal process GO:0051241 236 0.026
Mouse
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.026
regulation of nucleic acid templated transcription GO:1903506 165 0.025
cellular protein modification process GO:0006464 207 0.025
protein catabolic process GO:0030163 162 0.025
positive regulation of cellular process GO:0048522 332 0.025
Mouse
tube development GO:0035295 126 0.025
establishment of organelle localization GO:0051656 123 0.024
organonitrogen compound metabolic process GO:1901564 151 0.024
oxoacid metabolic process GO:0043436 47 0.024
protein complex biogenesis GO:0070271 186 0.024
establishment of localization in cell GO:0051649 318 0.024
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.023
regulation of locomotion GO:0040012 161 0.023
regulation of transcription dna templated GO:0006355 164 0.023
regulation of rna biosynthetic process GO:2001141 165 0.023
phosphorus metabolic process GO:0006793 232 0.023
regulation of macromolecule biosynthetic process GO:0010556 189 0.023
organic substance catabolic process GO:1901575 294 0.023
positive regulation of cellular metabolic process GO:0031325 178 0.023
innate immune response GO:0045087 190 0.022
posttranscriptional regulation of gene expression GO:0010608 166 0.022
Mouse
regulation of cell cycle process GO:0010564 145 0.022
posttranscriptional gene silencing GO:0016441 143 0.022
regulation of cellular ketone metabolic process GO:0010565 3 0.022
regulation of apoptotic signaling pathway GO:2001233 1 0.021
collagen and cuticulin based cuticle development GO:0040002 99 0.021
positive regulation of transcription dna templated GO:0045893 102 0.021
gene silencing GO:0016458 143 0.021
meiotic nuclear division GO:0007126 300 0.021
organelle assembly GO:0070925 214 0.021
Mouse
macromolecular complex assembly GO:0065003 193 0.021
Mouse
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.020
nucleobase containing compound catabolic process GO:0034655 114 0.020
Mouse
gene silencing by rna GO:0031047 143 0.020
cell fate commitment GO:0045165 139 0.020
regulation of response to stimulus GO:0048583 243 0.020
Mouse
regulation of lipid metabolic process GO:0019216 4 0.020
regulation of localization GO:0032879 194 0.020
carbohydrate derivative metabolic process GO:1901135 141 0.020
protein complex assembly GO:0006461 186 0.020
single fertilization GO:0007338 61 0.020
nucleic acid templated transcription GO:0097659 169 0.019
female gamete generation GO:0007292 254 0.019
actin filament based process GO:0030029 191 0.019
cellular catabolic process GO:0044248 199 0.019
actomyosin structure organization GO:0031032 154 0.019
positive regulation of biosynthetic process GO:0009891 109 0.019
regulation of cytoplasmic transport GO:1903649 3 0.019
actin cytoskeleton organization GO:0030036 184 0.019
positive regulation of gene expression GO:0010628 112 0.019
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.019
cellular component assembly involved in morphogenesis GO:0010927 183 0.018
myofibril assembly GO:0030239 154 0.018
regulation of cell division GO:0051302 142 0.018
response to external biotic stimulus GO:0043207 101 0.018
membrane organization GO:0061024 135 0.018
regulation of cell communication GO:0010646 176 0.018
Mouse
organic acid metabolic process GO:0006082 47 0.018
carboxylic acid metabolic process GO:0019752 34 0.018
posttranscriptional gene silencing by rna GO:0035194 143 0.018
epithelial tube morphogenesis GO:0060562 1 0.018
meiotic cell cycle GO:0051321 335 0.017
tissue development GO:0009888 112 0.017
rna interference GO:0016246 137 0.017
chromosome organization GO:0051276 104 0.017
regulation of organ morphogenesis GO:2000027 4 0.017
response to chemical GO:0042221 356 0.017
neuron differentiation GO:0030182 217 0.017
negative regulation of cellular biosynthetic process GO:0031327 65 0.017
positive regulation of rna metabolic process GO:0051254 103 0.017
neurogenesis GO:0022008 236 0.017
neuron development GO:0048666 199 0.017
positive regulation of rna biosynthetic process GO:1902680 102 0.017
digestive tract development GO:0048565 122 0.017
mitotic cell cycle process GO:1903047 194 0.017
positive regulation of vulval development GO:0040026 52 0.017
cellular nitrogen compound catabolic process GO:0044270 119 0.017
Mouse
cell morphogenesis involved in differentiation GO:0000904 112 0.017
sensory organ morphogenesis GO:0090596 2 0.016
regulation of meiosis GO:0040020 94 0.016
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.016
system process GO:0003008 136 0.016
inductive cell migration GO:0040039 145 0.016
neuron projection development GO:0031175 187 0.016
cellular response to dna damage stimulus GO:0006974 41 0.016
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.016
regulation of nuclear division GO:0051783 115 0.016
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.016
cellular ketone metabolic process GO:0042180 14 0.016
cuticle development GO:0042335 100 0.016
cellular response to abiotic stimulus GO:0071214 4 0.016
establishment of spindle orientation GO:0051294 34 0.016
spindle organization GO:0007051 92 0.015
organophosphate metabolic process GO:0019637 125 0.015
myosin filament assembly GO:0031034 138 0.015
positive regulation of response to stimulus GO:0048584 55 0.015
Mouse
phagocytosis GO:0006909 115 0.015
striated muscle myosin thick filament assembly GO:0071688 138 0.015
secretion by cell GO:0032940 138 0.015
negative regulation of cellular metabolic process GO:0031324 95 0.015
myosin filament organization GO:0031033 138 0.015
regulation of meiotic cell cycle GO:0051445 136 0.015
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.015
fertilization GO:0009566 63 0.015
negative regulation of nucleic acid templated transcription GO:1903507 53 0.015
positive regulation of cell migration GO:0030335 3 0.015
organic cyclic compound biosynthetic process GO:1901362 195 0.015
amine metabolic process GO:0009308 15 0.014
neuron projection morphogenesis GO:0048812 114 0.014
cell projection morphogenesis GO:0048858 148 0.014
cell part morphogenesis GO:0032990 152 0.014
ribonucleoprotein complex assembly GO:0022618 4 0.014
Mouse
regeneration GO:0031099 4 0.014
single organism catabolic process GO:0044712 129 0.014
phosphorylation GO:0016310 116 0.014
regulation of signal transduction GO:0009966 135 0.014
Mouse
intracellular receptor signaling pathway GO:0030522 2 0.014
apoptotic cell clearance GO:0043277 111 0.014
positive regulation of intracellular transport GO:0032388 2 0.014
cellular macromolecule localization GO:0070727 75 0.014
positive regulation of neurogenesis GO:0050769 4 0.014
cellular macromolecular complex assembly GO:0034622 184 0.014
Mouse
organic cyclic compound catabolic process GO:1901361 119 0.014
Mouse
cell projection organization GO:0030030 231 0.014
cell fate commitment involved in formation of primary germ layer GO:0060795 33 0.014
regulation of cellular protein metabolic process GO:0032268 75 0.014
response to biotic stimulus GO:0009607 101 0.013
nucleobase containing small molecule metabolic process GO:0055086 115 0.013
rna localization GO:0006403 3 0.013
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.013
generation of neurons GO:0048699 235 0.013
cellular amino acid metabolic process GO:0006520 15 0.013
regulation of nucleocytoplasmic transport GO:0046822 3 0.013
negative regulation of transcription dna templated GO:0045892 53 0.013
negative regulation of rna metabolic process GO:0051253 53 0.013
single organism biosynthetic process GO:0044711 91 0.013
regulation of cellular amino acid metabolic process GO:0006521 0 0.013
oogenesis GO:0048477 229 0.013
cell surface receptor signaling pathway GO:0007166 149 0.013
Mouse
nucleoside phosphate metabolic process GO:0006753 108 0.013
regulation of signaling GO:0023051 172 0.013
Mouse
response to other organism GO:0051707 101 0.013
establishment or maintenance of cell polarity GO:0007163 63 0.013
regulation of response to wounding GO:1903034 1 0.013
membrane invagination GO:0010324 98 0.013
axon development GO:0061564 163 0.013
digestive system development GO:0055123 122 0.013
cellular macromolecule catabolic process GO:0044265 73 0.013
chromatin assembly or disassembly GO:0006333 1 0.013
embryonic morphogenesis GO:0048598 152 0.013
proteolysis GO:0006508 61 0.013
defense response to other organism GO:0098542 100 0.013
epithelial cell proliferation GO:0050673 1 0.012
positive regulation of cell projection organization GO:0031346 4 0.012
development of primary male sexual characteristics GO:0046546 4 0.012
phosphate containing compound metabolic process GO:0006796 232 0.012
nucleotide metabolic process GO:0009117 108 0.012
mating behavior GO:0007617 32 0.012
negative regulation of gene expression epigenetic GO:0045814 2 0.012
tube morphogenesis GO:0035239 79 0.012
regulation of cellular amine metabolic process GO:0033238 0 0.012
phagocytosis engulfment GO:0006911 98 0.012
heterocycle catabolic process GO:0046700 119 0.012
Mouse
establishment of cell polarity GO:0030010 46 0.012
oocyte construction GO:0007308 2 0.012
regulation of cell motility GO:2000145 57 0.012
regulation of protein targeting GO:1903533 3 0.012
defense response to bacterium GO:0042742 86 0.012
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.012
regulation of cellular component movement GO:0051270 62 0.012
cell type specific apoptotic process GO:0097285 4 0.012
neuromuscular junction development GO:0007528 2 0.012
negative regulation of neurogenesis GO:0050768 4 0.012
purine nucleotide metabolic process GO:0006163 95 0.012
negative regulation of transcription from rna polymerase ii promoter GO:0000122 45 0.012
establishment of spindle localization GO:0051293 51 0.012
spindle localization GO:0051653 51 0.012
oocyte axis specification GO:0007309 2 0.011
engulfment of apoptotic cell GO:0043652 94 0.011
cell morphogenesis GO:0000902 163 0.011
regulation of mitotic cell cycle GO:0007346 76 0.011
male sex differentiation GO:0046661 86 0.011
positive regulation of cell communication GO:0010647 69 0.011
Mouse
cytokinesis GO:0000910 80 0.011
chromatin remodeling GO:0006338 2 0.011
intracellular signal transduction GO:0035556 96 0.011
Mouse
canonical wnt signaling pathway GO:0060070 3 0.011
lipid metabolic process GO:0006629 77 0.011
internal peptidyl lysine acetylation GO:0018393 3 0.011
cell proliferation GO:0008283 116 0.011
Mouse
regulation of catabolic process GO:0009894 57 0.011
localization within membrane GO:0051668 2 0.011
regulation of multi organism process GO:0043900 69 0.011
positive regulation of post embryonic development GO:0048582 54 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.011
regulation of synapse assembly GO:0051963 2 0.011
positive regulation of protein transport GO:0051222 4 0.011
regulation of protein import into nucleus GO:0042306 3 0.011
cellular protein localization GO:0034613 75 0.011
regulation of transport GO:0051049 91 0.011
cellular amine metabolic process GO:0044106 15 0.011
glycosyl compound metabolic process GO:1901657 100 0.011
response to acid chemical GO:0001101 4 0.011
positive regulation of epithelial cell proliferation GO:0050679 1 0.011
ribonucleotide metabolic process GO:0009259 99 0.011
negative regulation of biosynthetic process GO:0009890 65 0.011
negative regulation of cell cycle GO:0045786 53 0.011
single organism cellular localization GO:1902580 72 0.010
neurological system process GO:0050877 53 0.010
ribonucleoside metabolic process GO:0009119 98 0.010
dna templated transcription elongation GO:0006354 1 0.010
positive regulation of neuron differentiation GO:0045666 4 0.010
cyclic nucleotide biosynthetic process GO:0009190 2 0.010
negative regulation of rna biosynthetic process GO:1902679 53 0.010
regulation of cell proliferation GO:0042127 105 0.010
Mouse
chemotaxis GO:0006935 120 0.010
ribosome biogenesis GO:0042254 4 0.010
chromatin organization GO:0006325 32 0.010
ras protein signal transduction GO:0007265 31 0.010
detection of external stimulus GO:0009581 4 0.010
regulation of cell differentiation GO:0045595 81 0.010
Mouse
cyclic purine nucleotide metabolic process GO:0052652 2 0.010

rle-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.019
disease of cellular proliferation DOID:14566 0 0.013
cancer DOID:162 0 0.013
nervous system disease DOID:863 0 0.012
organ system cancer DOID:0050686 0 0.010