Caenorhabditis elegans

32 known processes

his-61 (CELE_F55G1.10)

Protein HIS-61

his-61 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
gonad development GO:0008406 840 0.994
hermaphrodite genitalia development GO:0040035 734 0.987
genitalia development GO:0048806 741 0.987
development of primary sexual characteristics GO:0045137 840 0.986
reproductive system development GO:0061458 850 0.986
meiotic cell cycle process GO:1903046 170 0.972
developmental process involved in reproduction GO:0003006 1165 0.971
reproductive structure development GO:0048608 850 0.969
digestive system development GO:0055123 122 0.965
Worm
embryo development ending in birth or egg hatching GO:0009792 2992 0.961
meiotic cell cycle GO:0051321 335 0.960
locomotion GO:0040011 1634 0.959
Worm
post embryonic development GO:0009791 2152 0.957
pharynx development GO:0060465 51 0.956
Worm
sexual reproduction GO:0019953 546 0.942
digestive tract development GO:0048565 122 0.937
Worm
single organism reproductive process GO:0044702 1196 0.934
embryo development GO:0009790 3052 0.923
sex differentiation GO:0007548 909 0.920
organ development GO:0048513 1102 0.915
tube development GO:0035295 126 0.909
Worm
multicellular organism reproduction GO:0032504 819 0.853
Worm
oviposition GO:0018991 364 0.841
Worm
transcription dna templated GO:0006351 168 0.803
negative regulation of rna biosynthetic process GO:1902679 53 0.801
multicellular organismal reproductive process GO:0048609 815 0.796
Worm
multicellular organismal reproductive behavior GO:0033057 384 0.795
Worm
defense response GO:0006952 296 0.774
Worm
transcription from rna polymerase ii promoter GO:0006366 149 0.697
regulation of transcription dna templated GO:0006355 164 0.692
regulation of rna biosynthetic process GO:2001141 165 0.690
organic cyclic compound biosynthetic process GO:1901362 195 0.682
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.607
nucleobase containing compound metabolic process GO:0006139 406 0.589
Yeast
regulation of nucleic acid templated transcription GO:1903506 165 0.583
aromatic compound biosynthetic process GO:0019438 192 0.571
rna biosynthetic process GO:0032774 169 0.566
nucleic acid templated transcription GO:0097659 169 0.548
regulation of rna metabolic process GO:0051252 173 0.532
nucleobase containing compound biosynthetic process GO:0034654 184 0.526
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.522
regulation of cellular metabolic process GO:0031323 305 0.519
rna metabolic process GO:0016070 228 0.518
cellular nitrogen compound biosynthetic process GO:0044271 192 0.511
negative regulation of transcription from rna polymerase ii promoter GO:0000122 45 0.509
regulation of cellular biosynthetic process GO:0031326 189 0.490
negative regulation of gene expression epigenetic GO:0045814 2 0.479
regulation of gene expression GO:0010468 366 0.476
negative regulation of nucleic acid templated transcription GO:1903507 53 0.451
gene expression GO:0010467 412 0.433
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.429
heterocycle biosynthetic process GO:0018130 187 0.426
fertilization GO:0009566 63 0.416
nucleic acid metabolic process GO:0090304 299 0.400
Yeast
negative regulation of transcription dna templated GO:0045892 53 0.391
cellular macromolecule biosynthetic process GO:0034645 247 0.390
regulation of primary metabolic process GO:0080090 292 0.385
innate immune response GO:0045087 190 0.384
multi organism reproductive process GO:0044703 867 0.375
Worm
regulation of nitrogen compound metabolic process GO:0051171 222 0.366
gamete generation GO:0007276 461 0.349
regulation of biosynthetic process GO:0009889 189 0.343
organic substance biosynthetic process GO:1901576 323 0.337
regulation of metabolic process GO:0019222 478 0.332
regulation of macromolecule metabolic process GO:0060255 421 0.320
negative regulation of biological process GO:0048519 567 0.314
macromolecule biosynthetic process GO:0009059 250 0.312
pronuclear migration GO:0035046 51 0.293
organelle organization GO:0006996 783 0.292
Worm
cellular biosynthetic process GO:0044249 315 0.277
meiotic nuclear division GO:0007126 300 0.252
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.252
multi organism behavior GO:0051705 389 0.242
Worm
negative regulation of gene expression GO:0010629 217 0.238
negative regulation of cellular biosynthetic process GO:0031327 65 0.237
body morphogenesis GO:0010171 620 0.233
negative regulation of biosynthetic process GO:0009890 65 0.231
negative regulation of cellular process GO:0048523 239 0.231
regulation of macromolecule biosynthetic process GO:0010556 189 0.225
meiotic chromosome segregation GO:0045132 139 0.218
germ cell development GO:0007281 351 0.213
single fertilization GO:0007338 61 0.208
negative regulation of metabolic process GO:0009892 240 0.207
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.205
vesicle mediated transport GO:0016192 852 0.204
establishment of localization GO:0051234 1171 0.202
reproductive behavior GO:0019098 387 0.192
Worm
chromosome organization GO:0051276 104 0.192
chromatin assembly or disassembly GO:0006333 1 0.191
behavior GO:0007610 527 0.190
Worm
biosynthetic process GO:0009058 323 0.187
regulation of gene expression epigenetic GO:0040029 163 0.184
immune response GO:0006955 192 0.177
female gamete generation GO:0007292 254 0.175
negative regulation of macromolecule metabolic process GO:0010605 229 0.171
multi organism reproductive behavior GO:0044705 387 0.169
Worm
single organism transport GO:0044765 447 0.168
nucleus organization GO:0006997 38 0.162
Worm
single organism localization GO:1902578 518 0.157
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.156
multi multicellular organism process GO:0044706 390 0.156
Worm
cellular response to dna damage stimulus GO:0006974 41 0.154
Yeast
determination of adult lifespan GO:0008340 812 0.151
dna metabolic process GO:0006259 74 0.147
Yeast
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.145
negative regulation of rna metabolic process GO:0051253 53 0.143
macromolecular complex subunit organization GO:0043933 320 0.143
vulval development GO:0040025 333 0.142
cellular response to stress GO:0033554 162 0.142
Yeast
negative regulation of cellular metabolic process GO:0031324 95 0.138
multicellular organismal aging GO:0010259 812 0.135
endocytosis GO:0006897 819 0.135
cell development GO:0048468 696 0.134
apoptotic process GO:0006915 478 0.127
programmed cell death GO:0012501 500 0.125
regulation of biological quality GO:0065008 741 0.123
death GO:0016265 547 0.123
positive regulation of cellular metabolic process GO:0031325 178 0.122
cellular component morphogenesis GO:0032989 318 0.119
receptor mediated endocytosis GO:0006898 715 0.119
oogenesis GO:0048477 229 0.116
aging GO:0007568 812 0.115
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.114
gene silencing GO:0016458 143 0.113
macromolecule localization GO:0033036 771 0.102
cell motility GO:0048870 313 0.097
dna repair GO:0006281 23 0.095
Yeast
cell cycle process GO:0022402 482 0.094
cellular component assembly involved in morphogenesis GO:0010927 183 0.091
cell death GO:0008219 547 0.086
chromatin organization GO:0006325 32 0.086
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.082
cellular protein modification process GO:0006464 207 0.082
single organism organelle organization GO:1902589 501 0.080
positive regulation of cellular biosynthetic process GO:0031328 109 0.079
regulation of vulval development GO:0040028 248 0.078
cell cycle GO:0007049 526 0.078
secretion by cell GO:0032940 138 0.076
positive regulation of cellular process GO:0048522 332 0.075
actomyosin structure organization GO:0031032 154 0.075
maintenance of location GO:0051235 580 0.074
regulation of meiotic cell cycle GO:0051445 136 0.074
cellular component biogenesis GO:0044085 297 0.074
striated muscle cell development GO:0055002 157 0.073
transport GO:0006810 1093 0.072
muscle structure development GO:0061061 191 0.071
negative regulation of nematode larval development GO:0061064 208 0.071
inductive cell migration GO:0040039 145 0.070
positive regulation of gene expression GO:0010628 112 0.069
lipid storage GO:0019915 565 0.069
anatomical structure formation involved in morphogenesis GO:0048646 250 0.069
protein metabolic process GO:0019538 422 0.069
lipid localization GO:0010876 573 0.068
protein modification process GO:0036211 207 0.068
macromolecule modification GO:0043412 218 0.067
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.066
cellular component assembly GO:0022607 293 0.064
cellular protein complex assembly GO:0043623 178 0.063
cellular protein metabolic process GO:0044267 279 0.062
cellular localization GO:0051641 360 0.061
protein complex subunit organization GO:0071822 280 0.061
positive regulation of nucleic acid templated transcription GO:1903508 102 0.060
establishment of localization in cell GO:0051649 318 0.059
negative regulation of vulval development GO:0040027 206 0.057
cell migration GO:0016477 306 0.057
myofibril assembly GO:0030239 154 0.054
positive regulation of rna biosynthetic process GO:1902680 102 0.054
macromolecule catabolic process GO:0009057 202 0.054
actin cytoskeleton organization GO:0030036 184 0.053
cytoskeleton organization GO:0007010 339 0.053
cell division GO:0051301 262 0.052
regulation of nematode larval development GO:0061062 260 0.051
actin filament based process GO:0030029 191 0.050
histone modification GO:0016570 30 0.050
positive regulation of rna metabolic process GO:0051254 103 0.049
protein complex biogenesis GO:0070271 186 0.049
regulation of multicellular organismal process GO:0051239 726 0.049
positive regulation of biosynthetic process GO:0009891 109 0.048
positive regulation of developmental growth GO:0048639 354 0.048
positive regulation of metabolic process GO:0009893 187 0.048
secretion GO:0046903 147 0.047
macromolecular complex assembly GO:0065003 193 0.046
muscle cell development GO:0055001 158 0.046
localization of cell GO:0051674 313 0.045
cellular macromolecular complex assembly GO:0034622 184 0.044
multicellular organism growth GO:0035264 385 0.044
muscle cell differentiation GO:0042692 171 0.044
regulation of cell cycle GO:0051726 194 0.043
catabolic process GO:0009056 318 0.043
regulation of multicellular organism growth GO:0040014 373 0.042
regulation of cellular component organization GO:0051128 248 0.041
striated muscle cell differentiation GO:0051146 158 0.041
developmental growth GO:0048589 412 0.041
cellular component movement GO:0006928 388 0.038
regulation of developmental growth GO:0048638 389 0.038
striated muscle myosin thick filament assembly GO:0071688 138 0.037
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.037
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.037
positive regulation of transcription dna templated GO:0045893 102 0.036
protein complex assembly GO:0006461 186 0.036
organelle assembly GO:0070925 214 0.036
organelle fission GO:0048285 363 0.036
myosin filament assembly GO:0031034 138 0.036
chromatin modification GO:0016568 32 0.034
regulation of meiosis GO:0040020 94 0.033
post embryonic organ development GO:0048569 336 0.033
phosphorus metabolic process GO:0006793 232 0.032
signaling GO:0023052 401 0.032
myosin filament organization GO:0031033 138 0.031
regulation of nuclear division GO:0051783 115 0.030
regulation of developmental process GO:0050793 684 0.029
growth GO:0040007 562 0.029
negative regulation of multicellular organismal process GO:0051241 236 0.029
single organism signaling GO:0044700 401 0.029
oocyte axis specification GO:0007309 2 0.029
regulation of organelle organization GO:0033043 164 0.028
positive regulation of developmental process GO:0051094 408 0.028
regulation of growth GO:0040008 409 0.027
negative regulation of developmental process GO:0051093 227 0.025
oocyte development GO:0048599 44 0.025
oocyte differentiation GO:0009994 45 0.025
positive regulation of growth GO:0045927 369 0.025
positive regulation of macromolecule metabolic process GO:0010604 149 0.024
negative regulation of post embryonic development GO:0048581 208 0.023
organelle localization GO:0051640 127 0.023
organic substance catabolic process GO:1901575 294 0.023
defense response to other organism GO:0098542 100 0.022
response to wounding GO:0009611 4 0.022
cellular catabolic process GO:0044248 199 0.021
response to chemical GO:0042221 356 0.021
signal transduction GO:0007165 317 0.020
defense response to bacterium GO:0042742 86 0.020
positive regulation of multicellular organism growth GO:0040018 352 0.020
intracellular signal transduction GO:0035556 96 0.020
sensory organ morphogenesis GO:0090596 2 0.020
regulation of response to stimulus GO:0048583 243 0.019
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.019
oocyte construction GO:0007308 2 0.019
small molecule metabolic process GO:0044281 186 0.019
ovulation GO:0030728 33 0.018
posttranscriptional regulation of gene expression GO:0010608 166 0.018
regulation of cell division GO:0051302 142 0.018
establishment of nucleus localization GO:0040023 55 0.017
positive regulation of nematode larval development GO:0061063 54 0.017
organonitrogen compound metabolic process GO:1901564 151 0.017
phosphate containing compound metabolic process GO:0006796 232 0.016
ribonucleotide metabolic process GO:0009259 99 0.016
chromosome segregation GO:0007059 180 0.016
regulation of multicellular organismal development GO:2000026 317 0.016
covalent chromatin modification GO:0016569 30 0.016
establishment of organelle localization GO:0051656 123 0.016
regulation of cell cycle process GO:0010564 145 0.016
protein catabolic process GO:0030163 162 0.015
positive regulation of multicellular organismal process GO:0051240 417 0.015
phosphorylation GO:0016310 116 0.015
single organism catabolic process GO:0044712 129 0.015
adult behavior GO:0030534 3 0.014
molting cycle GO:0042303 281 0.014
regulation of localization GO:0032879 194 0.014
organophosphate metabolic process GO:0019637 125 0.014
regulation of signal transduction GO:0009966 135 0.014
positive regulation of vulval development GO:0040026 52 0.014
posttranscriptional gene silencing GO:0016441 143 0.014
nucleobase containing small molecule metabolic process GO:0055086 115 0.014
nucleus localization GO:0051647 55 0.014
nucleoside triphosphate metabolic process GO:0009141 87 0.014
regulation of cellular ketone metabolic process GO:0010565 3 0.013
regulation of apoptotic signaling pathway GO:2001233 1 0.013
mitotic cell cycle process GO:1903047 194 0.013
response to abiotic stimulus GO:0009628 152 0.013
rna interference GO:0016246 137 0.013
regulation of post embryonic development GO:0048580 260 0.013
regulation of cellular amine metabolic process GO:0033238 0 0.013
positive regulation of cell cycle GO:0045787 55 0.013
skeletal muscle organ development GO:0060538 3 0.013
mitotic sister chromatid separation GO:0051306 13 0.013
neuromuscular junction development GO:0007528 2 0.012
defense response to gram negative bacterium GO:0050829 64 0.012
generation of neurons GO:0048699 235 0.012
cytokinesis GO:0000910 80 0.012
regulation of mitotic cell cycle GO:0007346 76 0.012
negative regulation of neurogenesis GO:0050768 4 0.012
response to external biotic stimulus GO:0043207 101 0.012
cellular amine metabolic process GO:0044106 15 0.012
protein oligomerization GO:0051259 4 0.012
regulation of cytoplasmic transport GO:1903649 3 0.012
nuclear migration GO:0007097 54 0.012
aromatic compound catabolic process GO:0019439 116 0.012
ribose phosphate metabolic process GO:0019693 99 0.011
synaptic growth at neuromuscular junction GO:0051124 1 0.011
regulation of cell communication GO:0010646 176 0.011
male gamete generation GO:0048232 41 0.011
cell morphogenesis GO:0000902 163 0.011
posttranscriptional gene silencing by rna GO:0035194 143 0.011
cellular amino acid metabolic process GO:0006520 15 0.011
amine metabolic process GO:0009308 15 0.011
spermatogenesis GO:0007283 41 0.011
regeneration GO:0031099 4 0.011
metaphase anaphase transition of cell cycle GO:0044784 15 0.011
organic cyclic compound catabolic process GO:1901361 119 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 43 0.011
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.011
single organism behavior GO:0044708 83 0.011
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 1 0.011
phagocytosis GO:0006909 115 0.011
head development GO:0060322 1 0.011
regulation of response to wounding GO:1903034 1 0.011
regulation of protein stability GO:0031647 3 0.010
proteolysis involved in cellular protein catabolic process GO:0051603 32 0.010
regulation of nucleocytoplasmic transport GO:0046822 3 0.010
nucleoside phosphate metabolic process GO:0006753 108 0.010
cellular macromolecule catabolic process GO:0044265 73 0.010
canonical wnt signaling pathway GO:0060070 3 0.010
gene silencing by rna GO:0031047 143 0.010
purine nucleotide metabolic process GO:0006163 95 0.010
cell projection organization GO:0030030 231 0.010

his-61 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.028
cancer DOID:162 0 0.019
disease of cellular proliferation DOID:14566 0 0.019
organ system cancer DOID:0050686 0 0.018
nervous system disease DOID:863 0 0.011