Caenorhabditis elegans

89 known processes

klc-2 (CELE_C18C4.10)

Protein KLC-2

klc-2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
multicellular organism reproduction GO:0032504 819 0.665
Fly
protein metabolic process GO:0019538 422 0.525
multicellular organismal reproductive behavior GO:0033057 384 0.411
embryo development GO:0009790 3052 0.364
protein modification process GO:0036211 207 0.362
sexual reproduction GO:0019953 546 0.353
Fly
post embryonic development GO:0009791 2152 0.351
cellular protein metabolic process GO:0044267 279 0.328
genitalia development GO:0048806 741 0.307
organ development GO:0048513 1102 0.298
macromolecule modification GO:0043412 218 0.290
establishment of localization GO:0051234 1171 0.264
cell cell signaling GO:0007267 118 0.263
receptor mediated endocytosis GO:0006898 715 0.254
defense response GO:0006952 296 0.230
single organism reproductive process GO:0044702 1196 0.225
Fly
cellular protein modification process GO:0006464 207 0.215
positive regulation of cellular process GO:0048522 332 0.203
single fertilization GO:0007338 61 0.192
single organism signaling GO:0044700 401 0.189
locomotion GO:0040011 1634 0.185
development of primary sexual characteristics GO:0045137 840 0.184
establishment of localization in cell GO:0051649 318 0.181
signaling GO:0023052 401 0.176
cytoskeleton organization GO:0007010 339 0.169
regulation of multicellular organismal development GO:2000026 317 0.165
gonad development GO:0008406 840 0.164
multicellular organismal reproductive process GO:0048609 815 0.162
Fly
oviposition GO:0018991 364 0.157
neuron differentiation GO:0030182 217 0.152
protein localization GO:0008104 205 0.150
protein phosphorylation GO:0006468 85 0.146
reproductive structure development GO:0048608 850 0.146
developmental process involved in reproduction GO:0003006 1165 0.145
Fly
endocytosis GO:0006897 819 0.144
multi organism reproductive process GO:0044703 867 0.140
Fly
multicellular organismal aging GO:0010259 812 0.137
cellular response to organic substance GO:0071310 119 0.137
negative regulation of vulval development GO:0040027 206 0.136
sex differentiation GO:0007548 909 0.130
aging GO:0007568 812 0.127
transport GO:0006810 1093 0.123
cell motility GO:0048870 313 0.118
generation of neurons GO:0048699 235 0.117
establishment of nucleus localization GO:0040023 55 0.116
regulation of developmental process GO:0050793 684 0.112
macromolecule localization GO:0033036 771 0.109
phosphorylation GO:0016310 116 0.108
multi organism behavior GO:0051705 389 0.107
fertilization GO:0009566 63 0.106
nervous system development GO:0007399 253 0.106
body morphogenesis GO:0010171 620 0.102
regulation of cellular component organization GO:0051128 248 0.100
multi organism reproductive behavior GO:0044705 387 0.100
reproductive behavior GO:0019098 387 0.099
embryo development ending in birth or egg hatching GO:0009792 2992 0.098
cell development GO:0048468 696 0.096
positive regulation of cell communication GO:0010647 69 0.095
single organism transport GO:0044765 447 0.095
pronuclear migration GO:0035046 51 0.093
immune response GO:0006955 192 0.093
synaptic transmission GO:0007268 106 0.091
neuron projection development GO:0031175 187 0.090
multi multicellular organism process GO:0044706 390 0.088
anatomical structure formation involved in morphogenesis GO:0048646 250 0.084
Fly
neuron development GO:0048666 199 0.082
cellular response to stress GO:0033554 162 0.079
death GO:0016265 547 0.078
behavior GO:0007610 527 0.078
organ morphogenesis GO:0009887 67 0.076
actin filament based process GO:0030029 191 0.076
gamete generation GO:0007276 461 0.075
Fly
negative regulation of post embryonic development GO:0048581 208 0.073
organic substance biosynthetic process GO:1901576 323 0.073
tube development GO:0035295 126 0.072
establishment of vesicle localization GO:0051650 23 0.071
organelle localization GO:0051640 127 0.068
response to biotic stimulus GO:0009607 101 0.067
establishment of organelle localization GO:0051656 123 0.067
lipid storage GO:0019915 565 0.066
cell fate commitment GO:0045165 139 0.064
nucleus localization GO:0051647 55 0.063
regulation of epithelial cell proliferation GO:0050678 1 0.062
head development GO:0060322 1 0.062
lipid localization GO:0010876 573 0.061
regulation of multicellular organismal process GO:0051239 726 0.061
regulation of growth GO:0040008 409 0.061
developmental growth GO:0048589 412 0.061
response to chemical GO:0042221 356 0.060
gene expression GO:0010467 412 0.059
growth GO:0040007 562 0.059
reproductive system development GO:0061458 850 0.059
regulation of vulval development GO:0040028 248 0.057
vesicle mediated transport GO:0016192 852 0.057
determination of adult lifespan GO:0008340 812 0.057
cellular macromolecule biosynthetic process GO:0034645 247 0.056
intracellular signal transduction GO:0035556 96 0.056
cellular protein localization GO:0034613 75 0.056
actin cytoskeleton organization GO:0030036 184 0.056
pole plasm assembly GO:0007315 2 0.055
cellular biosynthetic process GO:0044249 315 0.055
phosphorus metabolic process GO:0006793 232 0.054
cell migration GO:0016477 306 0.053
maintenance of location GO:0051235 580 0.053
regulation of biological quality GO:0065008 741 0.052
positive regulation of metabolic process GO:0009893 187 0.052
regulation of cellular biosynthetic process GO:0031326 189 0.052
regulation of multi organism process GO:0043900 69 0.051
regulation of protein localization GO:0032880 50 0.051
germ cell development GO:0007281 351 0.051
Fly
regulation of localization GO:0032879 194 0.050
hermaphrodite genitalia development GO:0040035 734 0.050
single organism organelle organization GO:1902589 501 0.050
negative regulation of biological process GO:0048519 567 0.050
biosynthetic process GO:0009058 323 0.050
innate immune response GO:0045087 190 0.050
phosphate containing compound metabolic process GO:0006796 232 0.049
negative regulation of multicellular organismal process GO:0051241 236 0.049
regulation of signaling GO:0023051 172 0.048
signal transduction GO:0007165 317 0.048
muscle tissue development GO:0060537 1 0.047
organic substance catabolic process GO:1901575 294 0.046
sensory organ morphogenesis GO:0090596 2 0.046
nuclear migration GO:0007097 54 0.046
nucleobase containing compound metabolic process GO:0006139 406 0.046
single organism localization GO:1902578 518 0.046
positive regulation of response to stimulus GO:0048584 55 0.046
protein complex subunit organization GO:0071822 280 0.046
cell projection organization GO:0030030 231 0.046
nucleic acid metabolic process GO:0090304 299 0.045
cellular response to chemical stimulus GO:0070887 129 0.043
positive regulation of signaling GO:0023056 66 0.043
regulation of developmental growth GO:0048638 389 0.043
muscle structure development GO:0061061 191 0.042
cellular localization GO:0051641 360 0.042
regulation of signal transduction GO:0009966 135 0.042
post embryonic organ development GO:0048569 336 0.040
regulation of cellular protein metabolic process GO:0032268 75 0.040
regulation of primary metabolic process GO:0080090 292 0.039
positive regulation of multicellular organismal process GO:0051240 417 0.038
vesicle localization GO:0051648 24 0.038
macromolecule biosynthetic process GO:0009059 250 0.035
vulval development GO:0040025 333 0.034
positive regulation of cellular metabolic process GO:0031325 178 0.034
cellular macromolecular complex assembly GO:0034622 184 0.034
rna localization GO:0006403 3 0.033
regulation of nervous system development GO:0051960 41 0.033
chromosome organization GO:0051276 104 0.032
cellular protein complex assembly GO:0043623 178 0.032
positive regulation of developmental process GO:0051094 408 0.032
organelle organization GO:0006996 783 0.032
regulation of molecular function GO:0065009 89 0.031
regulation of neurogenesis GO:0050767 40 0.031
striated muscle cell differentiation GO:0051146 158 0.031
cellular component biogenesis GO:0044085 297 0.031
protein catabolic process GO:0030163 162 0.030
multicellular organism growth GO:0035264 385 0.030
cellular component morphogenesis GO:0032989 318 0.029
cell surface receptor signaling pathway GO:0007166 149 0.029
cellular response to endogenous stimulus GO:0071495 32 0.029
muscle cell differentiation GO:0042692 171 0.029
negative regulation of nematode larval development GO:0061064 208 0.028
regulation of protein metabolic process GO:0051246 81 0.028
positive regulation of macromolecule metabolic process GO:0010604 149 0.028
tissue development GO:0009888 112 0.027
Fly
cellular component assembly GO:0022607 293 0.026
regulation of macromolecule biosynthetic process GO:0010556 189 0.026
macromolecular complex subunit organization GO:0043933 320 0.026
Mouse
regulation of macromolecule metabolic process GO:0060255 421 0.026
jnk cascade GO:0007254 8 0.025
enzyme linked receptor protein signaling pathway GO:0007167 50 0.025
organonitrogen compound metabolic process GO:1901564 151 0.025
digestive tract development GO:0048565 122 0.024
muscle cell development GO:0055001 158 0.024
regulation of gene expression GO:0010468 366 0.024
positive regulation of developmental growth GO:0048639 354 0.024
regulation of canonical wnt signaling pathway GO:0060828 1 0.024
actin filament organization GO:0007015 21 0.024
meiotic cell cycle GO:0051321 335 0.024
regulation of phosphorylation GO:0042325 45 0.023
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.023
neurogenesis GO:0022008 236 0.023
epithelial tube morphogenesis GO:0060562 1 0.023
stress activated mapk cascade GO:0051403 10 0.022
regulation of cellular metabolic process GO:0031323 305 0.022
positive regulation of growth GO:0045927 369 0.022
response to abiotic stimulus GO:0009628 152 0.022
protein complex biogenesis GO:0070271 186 0.022
small molecule metabolic process GO:0044281 186 0.021
regulation of nitrogen compound metabolic process GO:0051171 222 0.021
protein transport GO:0015031 45 0.021
negative regulation of developmental process GO:0051093 227 0.021
regulation of oviposition GO:0046662 43 0.021
regulation of multicellular organism growth GO:0040014 373 0.020
response to external stimulus GO:0009605 289 0.020
regulation of nematode larval development GO:0061062 260 0.020
apoptotic process GO:0006915 478 0.020
macromolecule catabolic process GO:0009057 202 0.020
striated muscle cell development GO:0055002 157 0.020
oocyte axis specification GO:0007309 2 0.020
peptidyl amino acid modification GO:0018193 58 0.020
regulation of metabolic process GO:0019222 478 0.020
regulation of phosphorus metabolic process GO:0051174 81 0.019
cell death GO:0008219 547 0.019
positive regulation of multicellular organism growth GO:0040018 352 0.019
regulation of meiotic cell cycle GO:0051445 136 0.019
regulation of transcription dna templated GO:0006355 164 0.019
single organism cellular localization GO:1902580 72 0.019
muscle organ development GO:0007517 26 0.019
synaptic vesicle recycling GO:0036465 3 0.019
cell growth GO:0016049 44 0.019
defense response to fungus GO:0050832 19 0.019
organic substance transport GO:0071702 113 0.018
oxidation reduction process GO:0055114 59 0.018
positive regulation of stem cell differentiation GO:2000738 1 0.018
positive regulation of phosphorus metabolic process GO:0010562 56 0.018
male gamete generation GO:0048232 41 0.018
secretion GO:0046903 147 0.018
cellular macromolecule localization GO:0070727 75 0.018
glycoprotein metabolic process GO:0009100 29 0.018
positive regulation of signal transduction GO:0009967 40 0.018
organelle fission GO:0048285 363 0.018
defense response to bacterium GO:0042742 86 0.017
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.017
positive regulation of gene expression GO:0010628 112 0.017
response to external biotic stimulus GO:0043207 101 0.017
regulation of post embryonic development GO:0048580 260 0.017
cell cycle process GO:0022402 482 0.017
macromolecular complex assembly GO:0065003 193 0.017
regulation of cell cycle GO:0051726 194 0.017
Fly
oocyte construction GO:0007308 2 0.017
meiotic nuclear division GO:0007126 300 0.017
negative regulation of cellular process GO:0048523 239 0.016
negative regulation of macromolecule metabolic process GO:0010605 229 0.016
response to endogenous stimulus GO:0009719 33 0.016
defense response to other organism GO:0098542 100 0.016
regulation of cellular component movement GO:0051270 62 0.016
transcription dna templated GO:0006351 168 0.016
oxoacid metabolic process GO:0043436 47 0.016
membrane organization GO:0061024 135 0.016
positive regulation of phosphate metabolic process GO:0045937 56 0.016
response to wounding GO:0009611 4 0.016
synaptic vesicle endocytosis GO:0048488 3 0.016
lipid metabolic process GO:0006629 77 0.016
molting cycle GO:0042303 281 0.015
digestive system development GO:0055123 122 0.015
regulation of cytoplasmic transport GO:1903649 3 0.015
regulation of behavior GO:0050795 97 0.015
protein complex assembly GO:0006461 186 0.015
single organism carbohydrate metabolic process GO:0044723 29 0.015
single organism catabolic process GO:0044712 129 0.015
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.015
response to acid chemical GO:0001101 4 0.015
regulation of biosynthetic process GO:0009889 189 0.015
oogenesis GO:0048477 229 0.015
Fly
negative regulation of cellular biosynthetic process GO:0031327 65 0.015
regulation of transport GO:0051049 91 0.015
response to endoplasmic reticulum stress GO:0034976 71 0.014
cellular component assembly involved in morphogenesis GO:0010927 183 0.014
Fly
regulation of cell proliferation GO:0042127 105 0.014
response to mechanical stimulus GO:0009612 28 0.014
canonical wnt signaling pathway GO:0060070 3 0.014
transcription from rna polymerase ii promoter GO:0006366 149 0.014
regulation of apoptotic signaling pathway GO:2001233 1 0.014
modification dependent protein catabolic process GO:0019941 32 0.014
regulation of cellular component size GO:0032535 40 0.014
endoplasmic reticulum unfolded protein response GO:0030968 66 0.014
muscle organ morphogenesis GO:0048644 4 0.014
female gamete generation GO:0007292 254 0.014
Fly
localization of cell GO:0051674 313 0.014
regulation of intracellular signal transduction GO:1902531 77 0.014
negative regulation of cell cycle GO:0045786 53 0.014
hyperosmotic response GO:0006972 19 0.014
positive regulation of cell cycle GO:0045787 55 0.014
synaptic growth at neuromuscular junction GO:0051124 1 0.013
negative regulation of metabolic process GO:0009892 240 0.013
organophosphate metabolic process GO:0019637 125 0.013
regulation of cell projection organization GO:0031344 38 0.013
secretion by cell GO:0032940 138 0.013
positive regulation of biosynthetic process GO:0009891 109 0.013
positive regulation of neurogenesis GO:0050769 4 0.013
cell cycle GO:0007049 526 0.013
regulation of nucleic acid templated transcription GO:1903506 165 0.013
chromosome segregation GO:0007059 180 0.013
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.013
sleep GO:0030431 4 0.013
positive regulation of nucleic acid templated transcription GO:1903508 102 0.013
negative regulation of neurogenesis GO:0050768 4 0.013
endomembrane system organization GO:0010256 22 0.013
cell matrix adhesion GO:0007160 1 0.012
positive regulation of cellular component organization GO:0051130 34 0.012
response to organic substance GO:0010033 131 0.012
axon development GO:0061564 163 0.012
neuromuscular junction development GO:0007528 2 0.012
response to inorganic substance GO:0010035 50 0.012
actomyosin structure organization GO:0031032 154 0.012
cellular amino acid metabolic process GO:0006520 15 0.012
proteolysis GO:0006508 61 0.012
protein localization to organelle GO:0033365 37 0.012
tissue morphogenesis GO:0048729 65 0.012
negative regulation of signal transduction GO:0009968 60 0.011
synapse organization GO:0050808 24 0.011
regulation of striated muscle contraction GO:0006942 4 0.011
zinc ion transmembrane transport GO:0071577 1 0.011
male anatomical structure morphogenesis GO:0090598 78 0.011
regulation of protein modification process GO:0031399 46 0.011
rna metabolic process GO:0016070 228 0.011
regeneration GO:0031099 4 0.011
negative regulation of cellular metabolic process GO:0031324 95 0.011
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.011
epithelial cell proliferation GO:0050673 1 0.011
lamellipodium assembly GO:0030032 2 0.011
regulation of cell communication GO:0010646 176 0.011
positive regulation of molecular function GO:0044093 61 0.011
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.011
signal transduction by phosphorylation GO:0023014 31 0.011
regulation of synapse assembly GO:0051963 2 0.011
regulation of reproductive process GO:2000241 66 0.011
myofibril assembly GO:0030239 154 0.010
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.010
rna biosynthetic process GO:0032774 169 0.010
amine metabolic process GO:0009308 15 0.010
regulation of cell differentiation GO:0045595 81 0.010
negative regulation of cellular protein metabolic process GO:0032269 27 0.010
rna interference GO:0016246 137 0.010
regulation of protein targeting GO:1903533 3 0.010
organic cyclic compound catabolic process GO:1901361 119 0.010

klc-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.027
nervous system disease DOID:863 0 0.011