Caenorhabditis elegans

0 known processes

sms-2 (CELE_F53H8.4)

Protein SMS-2

sms-2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development GO:0009790 3052 0.614
embryo development ending in birth or egg hatching GO:0009792 2992 0.404
locomotion GO:0040011 1634 0.359
single organism reproductive process GO:0044702 1196 0.327
post embryonic development GO:0009791 2152 0.249
developmental process involved in reproduction GO:0003006 1165 0.241
gamete generation GO:0007276 461 0.218
regulation of multicellular organismal process GO:0051239 726 0.209
cell motility GO:0048870 313 0.196
regulation of gene expression GO:0010468 366 0.195
neurogenesis GO:0022008 236 0.190
cell development GO:0048468 696 0.179
gonad development GO:0008406 840 0.173
organ development GO:0048513 1102 0.169
molting cycle GO:0042303 281 0.162
regulation of transcription dna templated GO:0006355 164 0.158
regulation of developmental process GO:0050793 684 0.155
rna biosynthetic process GO:0032774 169 0.152
cell migration GO:0016477 306 0.149
reproductive system development GO:0061458 850 0.143
positive regulation of gene expression GO:0010628 112 0.140
localization of cell GO:0051674 313 0.139
sex differentiation GO:0007548 909 0.134
endocytosis GO:0006897 819 0.133
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.132
regulation of macromolecule metabolic process GO:0060255 421 0.131
cell cycle GO:0007049 526 0.130
regulation of cell differentiation GO:0045595 81 0.122
vulval development GO:0040025 333 0.122
transcription dna templated GO:0006351 168 0.122
regulation of vulval development GO:0040028 248 0.122
gene expression GO:0010467 412 0.121
negative regulation of vulval development GO:0040027 206 0.118
nucleobase containing compound metabolic process GO:0006139 406 0.113
single organism organelle organization GO:1902589 501 0.112
signaling GO:0023052 401 0.112
neuron development GO:0048666 199 0.110
female gamete generation GO:0007292 254 0.108
cell projection organization GO:0030030 231 0.107
body morphogenesis GO:0010171 620 0.106
multicellular organism reproduction GO:0032504 819 0.105
aromatic compound biosynthetic process GO:0019438 192 0.105
regulation of metabolic process GO:0019222 478 0.102
regulation of multicellular organismal development GO:2000026 317 0.101
growth GO:0040007 562 0.100
hermaphrodite genitalia development GO:0040035 734 0.097
regulation of nucleic acid templated transcription GO:1903506 165 0.097
receptor mediated endocytosis GO:0006898 715 0.096
cell cycle process GO:0022402 482 0.096
transport GO:0006810 1093 0.091
death GO:0016265 547 0.091
transcription from rna polymerase ii promoter GO:0006366 149 0.090
multi organism reproductive process GO:0044703 867 0.090
axon development GO:0061564 163 0.090
neuron projection development GO:0031175 187 0.090
reproductive structure development GO:0048608 850 0.088
organelle organization GO:0006996 783 0.088
post embryonic organ development GO:0048569 336 0.088
development of primary sexual characteristics GO:0045137 840 0.088
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.086
cellular nitrogen compound biosynthetic process GO:0044271 192 0.085
generation of neurons GO:0048699 235 0.084
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.084
aging GO:0007568 812 0.082
regulation of biological quality GO:0065008 741 0.081
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.081
positive regulation of transcription dna templated GO:0045893 102 0.081
negative regulation of multicellular organismal process GO:0051241 236 0.080
regulation of nematode larval development GO:0061062 260 0.080
cellular macromolecule biosynthetic process GO:0034645 247 0.080
sexual reproduction GO:0019953 546 0.078
regulation of nitrogen compound metabolic process GO:0051171 222 0.078
response to external stimulus GO:0009605 289 0.076
response to chemical GO:0042221 356 0.075
vesicle mediated transport GO:0016192 852 0.074
single organism transport GO:0044765 447 0.074
nucleobase containing compound biosynthetic process GO:0034654 184 0.073
heterocycle biosynthetic process GO:0018130 187 0.073
multicellular organismal reproductive process GO:0048609 815 0.073
macromolecule localization GO:0033036 771 0.072
digestive tract development GO:0048565 122 0.072
mitotic nuclear division GO:0007067 89 0.070
genitalia development GO:0048806 741 0.070
regulation of multicellular organism growth GO:0040014 373 0.070
multicellular organism growth GO:0035264 385 0.069
organic substance biosynthetic process GO:1901576 323 0.068
establishment of localization GO:0051234 1171 0.068
cellular component movement GO:0006928 388 0.068
cellular biosynthetic process GO:0044249 315 0.068
positive regulation of multicellular organismal process GO:0051240 417 0.067
organelle fission GO:0048285 363 0.067
neuron differentiation GO:0030182 217 0.067
multicellular organismal aging GO:0010259 812 0.067
maintenance of location GO:0051235 580 0.066
developmental growth GO:0048589 412 0.066
lipid storage GO:0019915 565 0.065
regulation of macromolecule biosynthetic process GO:0010556 189 0.065
signal transduction GO:0007165 317 0.064
lipid localization GO:0010876 573 0.064
nervous system development GO:0007399 253 0.064
positive regulation of cellular process GO:0048522 332 0.064
oogenesis GO:0048477 229 0.064
positive regulation of macromolecule metabolic process GO:0010604 149 0.063
positive regulation of developmental growth GO:0048639 354 0.063
regulation of rna metabolic process GO:0051252 173 0.063
tube development GO:0035295 126 0.062
nucleic acid metabolic process GO:0090304 299 0.061
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.060
negative regulation of macromolecule metabolic process GO:0010605 229 0.059
regulation of growth GO:0040008 409 0.058
behavior GO:0007610 527 0.058
positive regulation of biosynthetic process GO:0009891 109 0.058
regulation of cellular metabolic process GO:0031323 305 0.057
organic cyclic compound biosynthetic process GO:1901362 195 0.057
multi organism behavior GO:0051705 389 0.057
positive regulation of metabolic process GO:0009893 187 0.055
neuron projection morphogenesis GO:0048812 114 0.055
negative regulation of gene expression GO:0010629 217 0.055
cellular component morphogenesis GO:0032989 318 0.055
regulation of developmental growth GO:0048638 389 0.054
rna metabolic process GO:0016070 228 0.054
negative regulation of developmental process GO:0051093 227 0.054
sensory organ morphogenesis GO:0090596 2 0.054
positive regulation of multicellular organism growth GO:0040018 352 0.054
macromolecule biosynthetic process GO:0009059 250 0.054
positive regulation of growth GO:0045927 369 0.053
tissue development GO:0009888 112 0.053
positive regulation of developmental process GO:0051094 408 0.053
regulation of primary metabolic process GO:0080090 292 0.053
nucleic acid templated transcription GO:0097659 169 0.052
meiotic nuclear division GO:0007126 300 0.052
embryonic morphogenesis GO:0048598 152 0.051
protein metabolic process GO:0019538 422 0.050
negative regulation of nematode larval development GO:0061064 208 0.049
anatomical structure formation involved in morphogenesis GO:0048646 250 0.049
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.048
regulation of cell motility GO:2000145 57 0.047
canonical wnt signaling pathway GO:0060070 3 0.047
establishment of localization in cell GO:0051649 318 0.046
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.046
cell death GO:0008219 547 0.046
cellular component biogenesis GO:0044085 297 0.046
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.045
determination of adult lifespan GO:0008340 812 0.045
cellular protein metabolic process GO:0044267 279 0.045
regulation of cellular component organization GO:0051128 248 0.044
organic substance catabolic process GO:1901575 294 0.044
carbohydrate derivative metabolic process GO:1901135 141 0.043
negative regulation of metabolic process GO:0009892 240 0.043
regulation of post embryonic development GO:0048580 260 0.043
digestive system development GO:0055123 122 0.043
regulation of biosynthetic process GO:0009889 189 0.043
head development GO:0060322 1 0.042
neuron recognition GO:0008038 83 0.042
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.042
programmed cell death GO:0012501 500 0.042
cell division GO:0051301 262 0.042
neuron projection guidance GO:0097485 82 0.042
negative regulation of post embryonic development GO:0048581 208 0.041
biosynthetic process GO:0009058 323 0.040
cell projection morphogenesis GO:0048858 148 0.040
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.040
macromolecular complex subunit organization GO:0043933 320 0.040
regulation of cellular biosynthetic process GO:0031326 189 0.040
single organism signaling GO:0044700 401 0.039
cell surface receptor signaling pathway GO:0007166 149 0.039
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.039
protein modification process GO:0036211 207 0.038
germ cell development GO:0007281 351 0.038
regulation of locomotion GO:0040012 161 0.038
epithelial cell proliferation GO:0050673 1 0.038
defense response GO:0006952 296 0.037
cellular component assembly GO:0022607 293 0.037
regulation of response to stimulus GO:0048583 243 0.036
cellular protein modification process GO:0006464 207 0.036
regulation of protein metabolic process GO:0051246 81 0.036
cellular localization GO:0051641 360 0.036
inductive cell migration GO:0040039 145 0.036
nucleoside triphosphate metabolic process GO:0009141 87 0.035
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.034
ribonucleoprotein complex assembly GO:0022618 4 0.034
multi organism reproductive behavior GO:0044705 387 0.034
macromolecule modification GO:0043412 218 0.033
regulation of rna biosynthetic process GO:2001141 165 0.033
taxis GO:0042330 128 0.033
gastrulation GO:0007369 58 0.032
reproductive behavior GO:0019098 387 0.031
multicellular organismal reproductive behavior GO:0033057 384 0.031
intracellular receptor signaling pathway GO:0030522 2 0.031
nucleoside metabolic process GO:0009116 99 0.031
protein phosphorylation GO:0006468 85 0.031
digestive tract morphogenesis GO:0048546 76 0.031
negative regulation of transcription dna templated GO:0045892 53 0.031
pattern specification process GO:0007389 59 0.030
regulation of cell communication GO:0010646 176 0.030
oviposition GO:0018991 364 0.030
regulation of cellular component movement GO:0051270 62 0.030
positive regulation of cellular biosynthetic process GO:0031328 109 0.030
regionalization GO:0003002 31 0.030
nucleotide metabolic process GO:0009117 108 0.030
chemotaxis GO:0006935 120 0.030
mitotic cell cycle process GO:1903047 194 0.029
cell morphogenesis GO:0000902 163 0.029
multi multicellular organism process GO:0044706 390 0.029
meiotic cell cycle GO:0051321 335 0.029
cuticle development GO:0042335 100 0.028
ribonucleoside triphosphate metabolic process GO:0009199 87 0.028
single organism localization GO:1902578 518 0.028
meiotic cell cycle process GO:1903046 170 0.028
regulation of localization GO:0032879 194 0.027
nucleobase containing small molecule metabolic process GO:0055086 115 0.027
tube morphogenesis GO:0035239 79 0.027
meiotic chromosome segregation GO:0045132 139 0.027
positive regulation of cellular metabolic process GO:0031325 178 0.027
cell fate commitment GO:0045165 139 0.027
segmentation GO:0035282 7 0.027
apoptotic process GO:0006915 478 0.027
system process GO:0003008 136 0.027
axonogenesis GO:0007409 102 0.027
cellular response to stress GO:0033554 162 0.026
negative regulation of biological process GO:0048519 567 0.026
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.026
regulation of organelle organization GO:0033043 164 0.026
response to wounding GO:0009611 4 0.026
striated muscle cell differentiation GO:0051146 158 0.026
regulation of cell fate specification GO:0042659 22 0.025
regulation of molecular function GO:0065009 89 0.025
positive regulation of nucleic acid templated transcription GO:1903508 102 0.025
protein complex subunit organization GO:0071822 280 0.025
muscle structure development GO:0061061 191 0.025
epithelium development GO:0060429 68 0.024
aromatic compound catabolic process GO:0019439 116 0.024
single organism behavior GO:0044708 83 0.024
cytoskeleton organization GO:0007010 339 0.024
regulation of cellular ketone metabolic process GO:0010565 3 0.024
regulation of signaling GO:0023051 172 0.024
negative regulation of cellular metabolic process GO:0031324 95 0.024
posttranscriptional gene silencing by rna GO:0035194 143 0.024
negative regulation of nucleic acid templated transcription GO:1903507 53 0.024
regulation of phosphorus metabolic process GO:0051174 81 0.024
phosphate containing compound metabolic process GO:0006796 232 0.024
macromolecular complex assembly GO:0065003 193 0.024
organophosphate metabolic process GO:0019637 125 0.023
establishment of organelle localization GO:0051656 123 0.023
organic cyclic compound catabolic process GO:1901361 119 0.023
regulation of catalytic activity GO:0050790 78 0.023
skeletal muscle organ development GO:0060538 3 0.023
regulation of mitotic cell cycle GO:0007346 76 0.023
regulation of nuclear division GO:0051783 115 0.022
rho protein signal transduction GO:0007266 2 0.022
purine ribonucleoside metabolic process GO:0046128 92 0.022
regulation of epithelial cell proliferation GO:0050678 1 0.022
negative regulation of transcription from rna polymerase ii promoter GO:0000122 45 0.022
negative regulation of cellular biosynthetic process GO:0031327 65 0.022
positive regulation of rna biosynthetic process GO:1902680 102 0.022
cell proliferation GO:0008283 116 0.022
cellular macromolecular complex assembly GO:0034622 184 0.022
neuron projection extension GO:1990138 37 0.021
striated muscle cell development GO:0055002 157 0.021
secretion by cell GO:0032940 138 0.021
chromosome segregation GO:0007059 180 0.020
positive regulation of catalytic activity GO:0043085 59 0.020
positive regulation of cell cycle GO:0045787 55 0.020
negative regulation of cellular process GO:0048523 239 0.020
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.020
regulation of cell division GO:0051302 142 0.020
muscle tissue development GO:0060537 1 0.020
cytokinesis GO:0000910 80 0.020
cell morphogenesis involved in differentiation GO:0000904 112 0.020
positive regulation of rna metabolic process GO:0051254 103 0.020
rna interference GO:0016246 137 0.020
adult behavior GO:0030534 3 0.020
purine containing compound metabolic process GO:0072521 95 0.020
protein localization GO:0008104 205 0.019
membrane organization GO:0061024 135 0.019
nucleoside phosphate metabolic process GO:0006753 108 0.019
membrane invagination GO:0010324 98 0.019
organ morphogenesis GO:0009887 67 0.019
cell cell signaling GO:0007267 118 0.019
actomyosin structure organization GO:0031032 154 0.019
posttranscriptional gene silencing GO:0016441 143 0.019
regulation of cell cycle GO:0051726 194 0.019
negative regulation of biosynthetic process GO:0009890 65 0.018
intracellular signal transduction GO:0035556 96 0.018
regulation of cell proliferation GO:0042127 105 0.018
cell part morphogenesis GO:0032990 152 0.018
epithelial tube morphogenesis GO:0060562 1 0.018
axon guidance GO:0007411 82 0.018
regulation of cell cycle process GO:0010564 145 0.018
glycosyl compound metabolic process GO:1901657 100 0.018
fertilization GO:0009566 63 0.018
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.018
response to abiotic stimulus GO:0009628 152 0.018
phosphorylation GO:0016310 116 0.018
negative regulation of rna biosynthetic process GO:1902679 53 0.018
secretion GO:0046903 147 0.018
cellular response to abiotic stimulus GO:0071214 4 0.017
cell recognition GO:0008037 85 0.017
nucleoside triphosphate catabolic process GO:0009143 72 0.017
purine nucleoside catabolic process GO:0006152 75 0.017
hormone transport GO:0009914 2 0.017
ribose phosphate metabolic process GO:0019693 99 0.017
regulation of cellular amine metabolic process GO:0033238 0 0.017
positive regulation of chromosome organization GO:2001252 2 0.017
catabolic process GO:0009056 318 0.016
response to other organism GO:0051707 101 0.016
spindle organization GO:0007051 92 0.016
signal release GO:0023061 28 0.016
regulation of cellular amino acid metabolic process GO:0006521 0 0.016
purine nucleotide catabolic process GO:0006195 75 0.016
oxoacid metabolic process GO:0043436 47 0.016
regulation of nucleotide catabolic process GO:0030811 35 0.016
muscle cell differentiation GO:0042692 171 0.016
cellular catabolic process GO:0044248 199 0.015
protein complex biogenesis GO:0070271 186 0.015
wnt signaling pathway GO:0016055 27 0.015
posttranscriptional regulation of gene expression GO:0010608 166 0.015
purine nucleoside triphosphate metabolic process GO:0009144 87 0.015
collagen and cuticulin based cuticle development GO:0040002 99 0.015
heterocycle catabolic process GO:0046700 119 0.015
regulation of cell fate commitment GO:0010453 22 0.015
protein catabolic process GO:0030163 162 0.015
stem cell differentiation GO:0048863 7 0.015
positive regulation of protein metabolic process GO:0051247 45 0.015
protein complex assembly GO:0006461 186 0.015
regulation of multi organism process GO:0043900 69 0.014
sister chromatid segregation GO:0000819 46 0.014
regulation of transport GO:0051049 91 0.014
chromosome organization GO:0051276 104 0.014
phagocytosis engulfment GO:0006911 98 0.014
muscle cell development GO:0055001 158 0.014
negative regulation of gene expression epigenetic GO:0045814 2 0.014
neurological system process GO:0050877 53 0.014
response to biotic stimulus GO:0009607 101 0.014
actin cytoskeleton organization GO:0030036 184 0.014
organonitrogen compound metabolic process GO:1901564 151 0.014
myosin filament assembly GO:0031034 138 0.014
amine metabolic process GO:0009308 15 0.013
regulation of purine nucleotide catabolic process GO:0033121 35 0.013
microtubule based process GO:0007017 182 0.013
regulation of neuron differentiation GO:0045664 40 0.013
purine ribonucleotide metabolic process GO:0009150 95 0.013
gene silencing by rna GO:0031047 143 0.013
cell matrix adhesion GO:0007160 1 0.013
gene silencing GO:0016458 143 0.013
organic acid metabolic process GO:0006082 47 0.013
cellular protein complex assembly GO:0043623 178 0.013
cell substrate adhesion GO:0031589 1 0.013
striated muscle myosin thick filament assembly GO:0071688 138 0.013
small molecule metabolic process GO:0044281 186 0.013
regulation of meiotic cell cycle GO:0051445 136 0.013
cell type specific apoptotic process GO:0097285 4 0.013
nucleoside catabolic process GO:0009164 78 0.013
negative regulation of rna metabolic process GO:0051253 53 0.013
regulation of signal transduction GO:0009966 135 0.013
g1 s transition of mitotic cell cycle GO:0000082 2 0.012
response to organic substance GO:0010033 131 0.012
response to heat GO:0009408 50 0.012
myofibril assembly GO:0030239 154 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.012
synaptic transmission GO:0007268 106 0.012
response to external biotic stimulus GO:0043207 101 0.012
ribonucleoside triphosphate catabolic process GO:0009203 72 0.012
myosin filament organization GO:0031033 138 0.012
oocyte differentiation GO:0009994 45 0.012
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.012
regulation of epithelial cell differentiation GO:0030856 4 0.012
organonitrogen compound catabolic process GO:1901565 90 0.012
enzyme linked receptor protein signaling pathway GO:0007167 50 0.012
purine nucleoside triphosphate catabolic process GO:0009146 72 0.012
purine nucleoside metabolic process GO:0042278 92 0.012
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 2 0.012
anterior posterior pattern specification GO:0009952 27 0.012
regulation of canonical wnt signaling pathway GO:0060828 1 0.012
cellular ketone metabolic process GO:0042180 14 0.012
regulation of cell migration GO:0030334 55 0.012
ribonucleoside metabolic process GO:0009119 98 0.012
small gtpase mediated signal transduction GO:0007264 32 0.012
ribonucleoside catabolic process GO:0042454 77 0.012
immune response GO:0006955 192 0.012
negative regulation of neurogenesis GO:0050768 4 0.012
macromolecule catabolic process GO:0009057 202 0.011
adult locomotory behavior GO:0008344 1 0.011
regulation of phosphate metabolic process GO:0019220 81 0.011
regulation of small gtpase mediated signal transduction GO:0051056 41 0.011
innate immune response GO:0045087 190 0.011
carbohydrate derivative catabolic process GO:1901136 82 0.011
actin filament based process GO:0030029 191 0.011
regulation of organ morphogenesis GO:2000027 4 0.011
ovulation GO:0030728 33 0.011
axonal fasciculation GO:0007413 79 0.011
ribosome biogenesis GO:0042254 4 0.011
organelle assembly GO:0070925 214 0.011
regulation of purine nucleotide metabolic process GO:1900542 37 0.011
regulation of nucleocytoplasmic transport GO:0046822 3 0.011
metal ion transport GO:0030001 49 0.011
regulation of gene expression epigenetic GO:0040029 163 0.010
nematode male tail tip morphogenesis GO:0045138 77 0.010
single organism catabolic process GO:0044712 129 0.010
cell cycle g1 s phase transition GO:0044843 2 0.010
regulation of hormone secretion GO:0046883 2 0.010
negative regulation of response to external stimulus GO:0032102 3 0.010
phosphorus metabolic process GO:0006793 232 0.010
cellular macromolecule catabolic process GO:0044265 73 0.010
regulation of meiosis GO:0040020 94 0.010
purine containing compound catabolic process GO:0072523 75 0.010
regulation of cytoplasmic transport GO:1903649 3 0.010
organic substance transport GO:0071702 113 0.010
peptidyl tyrosine phosphorylation GO:0018108 2 0.010
cellular amine metabolic process GO:0044106 15 0.010
single organism cellular localization GO:1902580 72 0.010

sms-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.033
nervous system disease DOID:863 0 0.015
cancer DOID:162 0 0.013
disease of cellular proliferation DOID:14566 0 0.013
organ system cancer DOID:0050686 0 0.013