Caenorhabditis elegans

11 known processes

perm-2 (CELE_C44B12.1)

Protein PERM-2

perm-2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development GO:0009790 3052 0.506
embryo development ending in birth or egg hatching GO:0009792 2992 0.479
developmental process involved in reproduction GO:0003006 1165 0.305
post embryonic development GO:0009791 2152 0.267
single organism reproductive process GO:0044702 1196 0.231
multicellular organismal aging GO:0010259 812 0.220
determination of adult lifespan GO:0008340 812 0.201
gamete generation GO:0007276 461 0.184
multicellular organismal reproductive process GO:0048609 815 0.171
multicellular organism reproduction GO:0032504 819 0.160
regulation of biological quality GO:0065008 741 0.158
germ cell development GO:0007281 351 0.153
organ development GO:0048513 1102 0.152
death GO:0016265 547 0.150
sexual reproduction GO:0019953 546 0.135
aging GO:0007568 812 0.123
cell death GO:0008219 547 0.114
behavior GO:0007610 527 0.113
multi organism reproductive process GO:0044703 867 0.113
vesicle mediated transport GO:0016192 852 0.108
macromolecule localization GO:0033036 771 0.102
locomotion GO:0040011 1634 0.098
transport GO:0006810 1093 0.097
single organism signaling GO:0044700 401 0.094
cell development GO:0048468 696 0.093
multi organism reproductive behavior GO:0044705 387 0.088
establishment of localization GO:0051234 1171 0.088
signaling GO:0023052 401 0.086
oviposition GO:0018991 364 0.083
lipid localization GO:0010876 573 0.082
development of primary sexual characteristics GO:0045137 840 0.080
growth GO:0040007 562 0.080
multi multicellular organism process GO:0044706 390 0.077
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.074
receptor mediated endocytosis GO:0006898 715 0.074
response to chemical GO:0042221 356 0.071
apoptotic process GO:0006915 478 0.069
lipid storage GO:0019915 565 0.067
maintenance of location GO:0051235 580 0.067
multi organism behavior GO:0051705 389 0.062
catabolic process GO:0009056 318 0.059
multicellular organismal reproductive behavior GO:0033057 384 0.057
regulation of multicellular organismal process GO:0051239 726 0.057
lipid metabolic process GO:0006629 77 0.056
endocytosis GO:0006897 819 0.056
reproductive behavior GO:0019098 387 0.055
cellular response to organic substance GO:0071310 119 0.055
female gamete generation GO:0007292 254 0.052
homeostatic process GO:0042592 51 0.049
sex differentiation GO:0007548 909 0.048
positive regulation of multicellular organismal process GO:0051240 417 0.047
post embryonic organ development GO:0048569 336 0.047
regulation of developmental process GO:0050793 684 0.047
positive regulation of growth GO:0045927 369 0.047
negative regulation of developmental process GO:0051093 227 0.046
developmental growth GO:0048589 412 0.045
negative regulation of nematode larval development GO:0061064 208 0.045
organelle assembly GO:0070925 214 0.044
regulation of developmental growth GO:0048638 389 0.044
cellular component movement GO:0006928 388 0.043
reproductive structure development GO:0048608 850 0.043
defense response GO:0006952 296 0.041
genitalia development GO:0048806 741 0.041
multicellular organism growth GO:0035264 385 0.041
hermaphrodite genitalia development GO:0040035 734 0.040
regulation of growth GO:0040008 409 0.040
cell migration GO:0016477 306 0.039
regulation of multicellular organism growth GO:0040014 373 0.039
oogenesis GO:0048477 229 0.037
cellular localization GO:0051641 360 0.036
aromatic compound catabolic process GO:0019439 116 0.036
positive regulation of developmental process GO:0051094 408 0.035
body morphogenesis GO:0010171 620 0.034
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.033
organelle organization GO:0006996 783 0.033
positive regulation of multicellular organism growth GO:0040018 352 0.033
single organism localization GO:1902578 518 0.032
macromolecule catabolic process GO:0009057 202 0.030
head development GO:0060322 1 0.030
cell surface receptor signaling pathway GO:0007166 149 0.029
cellular component biogenesis GO:0044085 297 0.029
myosin filament assembly GO:0031034 138 0.028
cell motility GO:0048870 313 0.028
cellular component assembly involved in morphogenesis GO:0010927 183 0.028
myosin filament organization GO:0031033 138 0.027
cellular response to chemical stimulus GO:0070887 129 0.027
system process GO:0003008 136 0.027
positive regulation of developmental growth GO:0048639 354 0.026
programmed cell death GO:0012501 500 0.026
muscle structure development GO:0061061 191 0.025
localization of cell GO:0051674 313 0.025
organonitrogen compound metabolic process GO:1901564 151 0.025
muscle tissue development GO:0060537 1 0.024
myofibril assembly GO:0030239 154 0.023
striated muscle myosin thick filament assembly GO:0071688 138 0.023
regulation of response to stimulus GO:0048583 243 0.022
establishment of localization in cell GO:0051649 318 0.022
regulation of signal transduction GO:0009966 135 0.022
anatomical structure formation involved in morphogenesis GO:0048646 250 0.021
cytoskeleton organization GO:0007010 339 0.021
molting cycle GO:0042303 281 0.021
small molecule metabolic process GO:0044281 186 0.021
vulval development GO:0040025 333 0.021
response to endogenous stimulus GO:0009719 33 0.021
muscle cell development GO:0055001 158 0.020
cellular component morphogenesis GO:0032989 318 0.019
organic substance catabolic process GO:1901575 294 0.019
cell division GO:0051301 262 0.019
negative regulation of multicellular organismal process GO:0051241 236 0.019
protein complex biogenesis GO:0070271 186 0.018
muscle cell differentiation GO:0042692 171 0.018
ribonucleotide metabolic process GO:0009259 99 0.017
actomyosin structure organization GO:0031032 154 0.017
protein localization GO:0008104 205 0.017
protein metabolic process GO:0019538 422 0.017
cell proliferation GO:0008283 116 0.017
actin filament based process GO:0030029 191 0.016
regulation of cell proliferation GO:0042127 105 0.016
nucleotide metabolic process GO:0009117 108 0.016
response to organic substance GO:0010033 131 0.016
biosynthetic process GO:0009058 323 0.016
cellular component assembly GO:0022607 293 0.015
cellular biosynthetic process GO:0044249 315 0.015
negative regulation of biological process GO:0048519 567 0.015
regulation of apoptotic signaling pathway GO:2001233 1 0.015
reproductive system development GO:0061458 850 0.015
nervous system development GO:0007399 253 0.014
memory GO:0007613 3 0.014
organic cyclic compound catabolic process GO:1901361 119 0.014
cellular catabolic process GO:0044248 199 0.014
regulation of multicellular organismal development GO:2000026 317 0.014
engulfment of apoptotic cell GO:0043652 94 0.014
striated muscle cell development GO:0055002 157 0.014
signal transduction GO:0007165 317 0.014
protein complex subunit organization GO:0071822 280 0.014
amine metabolic process GO:0009308 15 0.014
response to oxygen containing compound GO:1901700 44 0.014
organophosphate metabolic process GO:0019637 125 0.013
negative regulation of macromolecule metabolic process GO:0010605 229 0.013
striated muscle cell differentiation GO:0051146 158 0.013
apoptotic cell clearance GO:0043277 111 0.013
regulation of post embryonic development GO:0048580 260 0.013
gastrulation GO:0007369 58 0.013
response to abiotic stimulus GO:0009628 152 0.012
regulation of catalytic activity GO:0050790 78 0.012
intracellular transport GO:0046907 77 0.012
carboxylic acid metabolic process GO:0019752 34 0.012
negative regulation of metabolic process GO:0009892 240 0.012
tissue development GO:0009888 112 0.012
nucleoside metabolic process GO:0009116 99 0.012
actin cytoskeleton organization GO:0030036 184 0.012
positive regulation of metabolic process GO:0009893 187 0.012
single organism biosynthetic process GO:0044711 91 0.012
nucleoside phosphate metabolic process GO:0006753 108 0.012
regulation of cell communication GO:0010646 176 0.012
macromolecular complex assembly GO:0065003 193 0.012
protein catabolic process GO:0030163 162 0.012
cellular amine metabolic process GO:0044106 15 0.012
protein complex assembly GO:0006461 186 0.012
regulation of lipid metabolic process GO:0019216 4 0.012
inductive cell migration GO:0040039 145 0.011
phosphorus metabolic process GO:0006793 232 0.011
posttranscriptional gene silencing GO:0016441 143 0.011
organic cyclic compound biosynthetic process GO:1901362 195 0.011
ribose phosphate metabolic process GO:0019693 99 0.011
cellular response to hormone stimulus GO:0032870 14 0.011
purine nucleotide metabolic process GO:0006163 95 0.011
posttranscriptional gene silencing by rna GO:0035194 143 0.011
response to external stimulus GO:0009605 289 0.011
glycosyl compound catabolic process GO:1901658 79 0.011
neuromuscular junction development GO:0007528 2 0.011
oocyte development GO:0048599 44 0.011
membrane invagination GO:0010324 98 0.011
nucleobase containing small molecule metabolic process GO:0055086 115 0.011
organic substance biosynthetic process GO:1901576 323 0.011
regulation of metabolic process GO:0019222 478 0.010
nucleobase containing compound metabolic process GO:0006139 406 0.010
phosphate containing compound metabolic process GO:0006796 232 0.010
organic substance transport GO:0071702 113 0.010
regulation of cellular metabolic process GO:0031323 305 0.010
organonitrogen compound catabolic process GO:1901565 90 0.010
cellular lipid metabolic process GO:0044255 40 0.010
cellular response to topologically incorrect protein GO:0035967 76 0.010
proteolysis GO:0006508 61 0.010
regulation of macromolecule metabolic process GO:0060255 421 0.010
cellular response to endogenous stimulus GO:0071495 32 0.010
defense response to bacterium GO:0042742 86 0.010

perm-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.023
disease of anatomical entity DOID:7 0 0.023
aplastic anemia DOID:12449 0 0.011
bone marrow disease DOID:4961 0 0.011
anemia DOID:2355 0 0.011
hematopoietic system disease DOID:74 0 0.011